RU2336307C2 - Способ получения липидов (варианты) и липиды, полученные этим способом - Google Patents

Способ получения липидов (варианты) и липиды, полученные этим способом Download PDF

Info

Publication number
RU2336307C2
RU2336307C2 RU2002119551/13A RU2002119551A RU2336307C2 RU 2336307 C2 RU2336307 C2 RU 2336307C2 RU 2002119551/13 A RU2002119551/13 A RU 2002119551/13A RU 2002119551 A RU2002119551 A RU 2002119551A RU 2336307 C2 RU2336307 C2 RU 2336307C2
Authority
RU
Russia
Prior art keywords
lipids
microorganisms
cells
acid
fermentation medium
Prior art date
Application number
RU2002119551/13A
Other languages
English (en)
Russian (ru)
Other versions
RU2002119551A (ru
Inventor
Крайг М. РУКЕР (US)
Крайг М. РУКЕР
Свитин Патрик ЭДУ-ПЕЗАХ (US)
Свитин Патрик ЭДУ-ПЕЗАХ
Брайан С. ИНГЕЛЬГАРДТ (US)
Брайан С. ИНГЕЛЬГАРДТ
Джордж Т.Ш. ВИДЕР (US)
Джордж Т.Ш. ВИДЕР
Original Assignee
Мартек Биосайнсис Корпорейшн
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22647287&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RU2336307(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Мартек Биосайнсис Корпорейшн filed Critical Мартек Биосайнсис Корпорейшн
Publication of RU2002119551A publication Critical patent/RU2002119551A/ru
Application granted granted Critical
Publication of RU2336307C2 publication Critical patent/RU2336307C2/ru

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B3/00—Refining fats or fatty oils
    • C11B3/006—Refining fats or fatty oils by extraction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B1/00—Production of fats or fatty oils from raw materials
    • C11B1/02—Pretreatment
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B3/00—Refining fats or fatty oils
    • C11B3/001—Refining fats or fatty oils by a combination of two or more of the means hereafter
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/06—Lysis of microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P23/00—Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P25/00—Preparation of compounds containing alloxazine or isoalloxazine nucleus, e.g. riboflavin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00—Preparation of steroids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6432—Eicosapentaenoic acids [EPA]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6434—Docosahexenoic acids [DHA]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6463—Glycerides obtained from glyceride producing microorganisms, e.g. single cell oil
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6472—Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Virology (AREA)
  • Cell Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Fats And Perfumes (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Steroid Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
RU2002119551/13A 2000-01-19 2001-01-19 Способ получения липидов (варианты) и липиды, полученные этим способом RU2336307C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17712500P 2000-01-19 2000-01-19
US60/177,125 2000-01-19

Publications (2)

Publication Number Publication Date
RU2002119551A RU2002119551A (ru) 2004-02-20
RU2336307C2 true RU2336307C2 (ru) 2008-10-20

Family

ID=22647287

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2002119551/13A RU2336307C2 (ru) 2000-01-19 2001-01-19 Способ получения липидов (варианты) и липиды, полученные этим способом

Country Status (23)

Country Link
US (8) US6750048B2 (enExample)
EP (4) EP2302065A1 (enExample)
JP (5) JP4020642B2 (enExample)
KR (8) KR101180462B1 (enExample)
CN (1) CN100460513C (enExample)
AT (1) ATE485385T1 (enExample)
AU (7) AU780619B2 (enExample)
BR (1) BR0107699B1 (enExample)
CA (2) CA2397655C (enExample)
CZ (1) CZ303446B6 (enExample)
DE (1) DE60143287D1 (enExample)
DK (1) DK1252324T3 (enExample)
ES (3) ES2735987T3 (enExample)
HU (1) HUP0300556A3 (enExample)
IL (5) IL150772A0 (enExample)
MX (4) MX232239B (enExample)
NO (2) NO20023449L (enExample)
NZ (1) NZ520287A (enExample)
PL (1) PL356587A1 (enExample)
PT (1) PT1252324E (enExample)
RU (1) RU2336307C2 (enExample)
WO (1) WO2001053512A1 (enExample)
ZA (1) ZA200205790B (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2605328C2 (ru) * 2011-02-16 2016-12-20 Соликс Алгредиентс, Инк. Композиция, набор и способ извлечения целевых соединений из биомассы
RU2744913C2 (ru) * 2016-12-27 2021-03-17 Эвоник Оперейшенс ГмбХ Способ выделения липидов из липидсодержащей биомассы
RU2776914C1 (ru) * 2018-11-09 2022-07-28 Эвоник Оперейшенс ГмбХ Способ получения биомассы, которая может легко расщепляться и которая характеризуется повышенным содержанием полиненасыщенных жирных кислот

Families Citing this family (207)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2289648C (en) 1998-03-17 2004-06-01 Conlinco, Inc. Conjugated linoleic acid compositions
US7078051B1 (en) 1998-08-11 2006-07-18 Natural Asa Conjugated linoleic acid alkyl esters in feedstuffs and food
US7776353B1 (en) 1998-03-17 2010-08-17 Aker Biomarine Asa Conjugated linoleic acid compositions
US7101914B2 (en) 1998-05-04 2006-09-05 Natural Asa Isomer enriched conjugated linoleic acid compositions
RU2336307C2 (ru) 2000-01-19 2008-10-20 Мартек Биосайнсис Корпорейшн Способ получения липидов (варианты) и липиды, полученные этим способом
AU5144901A (en) 2000-04-06 2001-10-23 Conlinco Inc Conjugated linoleic acid compositions
US6756405B2 (en) 2000-04-18 2004-06-29 Natural Asa Conjugated linoleic acid powder
EP1178118A1 (en) * 2000-08-02 2002-02-06 Dsm N.V. Isolation of microbial oils
US6677470B2 (en) 2001-11-20 2004-01-13 Natural Asa Functional acylglycerides
US7419596B2 (en) * 2001-12-12 2008-09-02 Martek Biosciences Corporation Extraction and winterization of lipids from oilseed and microbial sources
WO2003092628A2 (en) 2002-05-03 2003-11-13 Martek Biosciences Corporation High-quality lipids and methods for producing by enzymatic liberation from biomass
US6743931B2 (en) 2002-09-24 2004-06-01 Natural Asa Conjugated linoleic acid compositions
EP2759599A3 (en) 2003-10-02 2014-12-10 DSM IP Assets B.V. Production of high levels of DHA in microalgae using modified amounts of chloride and potassium
AU2005209003A1 (en) 2004-01-26 2005-08-11 Martek Biosciences Corporation Method for the separation of phospholipids from phospholipid-containing materials
ES2546484T3 (es) 2005-03-18 2015-09-24 Dsm Ip Assets B.V. Producción de carotenoides en levadura y hongos oleaginosos
US8048652B2 (en) * 2005-05-12 2011-11-01 Martek Biosciences Corporation Biomass hydrolysate and uses and production thereof
EP1899453B1 (en) 2005-06-07 2013-12-18 Ocean Nutrition Canada Limited Eukaryotic microorganisms for producing lipids and antioxidants
WO2007005725A2 (en) 2005-07-01 2007-01-11 Martek Biosciences Corporation Polyunsaturated fatty acid-containing oil product and uses and production thereof
US8277849B2 (en) * 2006-01-19 2012-10-02 Solazyme, Inc. Microalgae-derived compositions for improving the health and appearance of skin
US8298548B2 (en) 2007-07-18 2012-10-30 Solazyme, Inc. Compositions for improving the health and appearance of skin
US8110670B2 (en) 2006-05-19 2012-02-07 Ls9, Inc. Enhanced production of fatty acid derivatives
US20100242345A1 (en) * 2006-05-19 2010-09-30 LS9, Inc Production of fatty acids & derivatives thereof
WO2008004900A1 (en) * 2006-07-05 2008-01-10 Photonz Corporation Limited Production of ultrapure epa and polar lipids from largely heterotrophic culture
JP4854418B2 (ja) * 2006-07-28 2012-01-18 花王株式会社 ドデカヒドロ−３ａ，６，６，９ａ−テトラメチルナフト［２，１−ｂ］フラン原料の製造方法
JP5531324B2 (ja) * 2006-08-01 2014-06-25 ディーエスエム ニュートリショナル プロダクツ アーゲー 油生産微生物およびその改変方法
US8691555B2 (en) 2006-09-28 2014-04-08 Dsm Ip Assests B.V. Production of carotenoids in oleaginous yeast and fungi
US8262776B2 (en) * 2006-10-13 2012-09-11 General Atomics Photosynthetic carbon dioxide sequestration and pollution abatement
US8088614B2 (en) * 2006-11-13 2012-01-03 Aurora Algae, Inc. Methods and compositions for production and purification of biofuel from plants and microalgae
RS20090413A (sr) * 2007-04-03 2010-06-30 E. I. Du Pont De Nemours And Company Multizimi i njihova upotreba u proizvodnji polinezasićenih masnih kiselina
US20090004715A1 (en) 2007-06-01 2009-01-01 Solazyme, Inc. Glycerol Feedstock Utilization for Oil-Based Fuel Manufacturing
WO2008155410A1 (en) * 2007-06-21 2008-12-24 Novozymes A/S Production of lipids containing poly-unsaturated fatty acids
WO2009006317A1 (en) * 2007-06-29 2009-01-08 Martek Biosciences Corporation Production and purification of esters of polyunsaturated fatty acids
BRPI0815860B1 (pt) * 2007-09-12 2021-04-20 Dsm Ip Assets B.V. métodos para produzir um óleo biológico
CA2692266C (en) * 2007-09-27 2019-04-16 Ls9, Inc. Reduction of the toxic effect of impurities from raw materials by extractive fermentation
WO2009058799A1 (en) * 2007-11-01 2009-05-07 Wake Forest University School Of Medicine Compositions and methods for prevention and treatment of mammalian diseases
US8343753B2 (en) * 2007-11-01 2013-01-01 Wake Forest University School Of Medicine Compositions, methods, and kits for polyunsaturated fatty acids from microalgae
WO2009149470A1 (en) 2008-06-06 2009-12-10 Aurora Biofuels, Inc. Vcp-based vectors for algal cell transformation
US20100022393A1 (en) * 2008-07-24 2010-01-28 Bertrand Vick Glyphosate applications in aquaculture
WO2010036334A1 (en) * 2008-09-23 2010-04-01 LiveFuels, Inc. Systems and methods for producing biofuels from algae
US20100236137A1 (en) * 2008-09-23 2010-09-23 LiveFuels, Inc. Systems and methods for producing eicosapentaenoic acid and docosahexaenoic acid from algae
US20100297331A1 (en) * 2008-10-14 2010-11-25 Solazyme, Inc. Reduced Fat Foods Containing High-Lipid Microalgae with Improved Sensory Properties
CN104770424A (zh) * 2008-10-14 2015-07-15 索拉兹米公司 微藻生物质的食品组合物
US20100297323A1 (en) * 2008-10-14 2010-11-25 Solazyme, Inc. Gluten-free Foods Containing Microalgae
US20100297325A1 (en) * 2008-10-14 2010-11-25 Solazyme, Inc. Egg Products Containing Microalgae
US9896642B2 (en) 2008-10-14 2018-02-20 Corbion Biotech, Inc. Methods of microbial oil extraction and separation
US8927522B2 (en) 2008-10-14 2015-01-06 Solazyme, Inc. Microalgal polysaccharide compositions
US20100303961A1 (en) * 2008-10-14 2010-12-02 Solazyme, Inc. Methods of Inducing Satiety
US20160324167A1 (en) 2008-10-14 2016-11-10 Terravia Holdings, Inc. Novel microalgal food compositions
US20100303990A1 (en) * 2008-10-14 2010-12-02 Solazyme, Inc. High Protein and High Fiber Algal Food Materials
US20100297295A1 (en) * 2008-10-14 2010-11-25 Solazyme, Inc. Microalgae-Based Beverages
US20100303957A1 (en) * 2008-10-14 2010-12-02 Solazyme, Inc. Edible Oil and Processes for Its Production from Microalgae
US20100303989A1 (en) * 2008-10-14 2010-12-02 Solazyme, Inc. Microalgal Flour
US8809037B2 (en) 2008-10-24 2014-08-19 Bioprocessh20 Llc Systems, apparatuses and methods for treating wastewater
US8557249B2 (en) 2008-11-07 2013-10-15 Solazyme, Inc. Cosmetic compositions comprising microalgal components
US20110239318A1 (en) * 2008-11-18 2011-09-29 LiveFuels, Inc. Methods for producing fish with high lipid content
EP2370555B1 (en) 2008-11-28 2016-04-20 Solazyme, Inc. Production of tailored oils in heterotrophic microorganisms
US20110256594A1 (en) * 2008-12-08 2011-10-20 Sapphire Energy, Inc Removal of nitrogen from a chlorophyll or pheophytin containing biomass
US8940340B2 (en) * 2009-01-22 2015-01-27 Aurora Algae, Inc. Systems and methods for maintaining the dominance of Nannochloropsis in an algae cultivation system
JP2012516852A (ja) 2009-02-02 2012-07-26 マーテック バイオサイエンシーズ コーポレーション 認知機能改善および心拍数低下のための方法
US8143051B2 (en) * 2009-02-04 2012-03-27 Aurora Algae, Inc. Systems and methods for maintaining the dominance and increasing the biomass production of nannochloropsis in an algae cultivation system
SE534278C2 (sv) * 2009-02-17 2011-06-28 Alfa Laval Corp Ab Ett kontinuerligt förfarande för isolering av oljor från alger eller mikroorganismer
PL2408922T3 (pl) 2009-03-19 2017-02-28 Dsm Ip Assets B.V. Traustochytrydy, kompozycje kwasów tłuszczowych i sposoby ich wytwarzania, i ich zastosowania
US8207363B2 (en) * 2009-03-19 2012-06-26 Martek Biosciences Corporation Thraustochytrids, fatty acid compositions, and methods of making and uses thereof
US8476060B2 (en) * 2009-04-13 2013-07-02 Board Of Regents, The University Of Texas System Process for separating lipids from a biomass
US8753851B2 (en) 2009-04-17 2014-06-17 LiveFuels, Inc. Systems and methods for culturing algae with bivalves
US20100297749A1 (en) * 2009-04-21 2010-11-25 Sapphire Energy, Inc. Methods and systems for biofuel production
WO2010124125A2 (en) 2009-04-22 2010-10-28 Robert Fulton Fluidizable algae-based powdered fuel and methods for making and using same
BRPI1015313B1 (pt) 2009-04-27 2021-06-01 Genomatica, Inc. Método fermentativo para produzir um éster de ácido graxo empregando um microorganismo geneticamente modificado e método para a produção de ésteres de ácidos graxos
US9187778B2 (en) 2009-05-04 2015-11-17 Aurora Algae, Inc. Efficient light harvesting
BRPI1012026A2 (pt) 2009-05-26 2018-07-17 Solazyme Inc fracionamento de biomassa microbiana contendo óleo
US8809046B2 (en) 2011-04-28 2014-08-19 Aurora Algae, Inc. Algal elongases
US8865468B2 (en) * 2009-10-19 2014-10-21 Aurora Algae, Inc. Homologous recombination in an algal nuclear genome
US8865452B2 (en) * 2009-06-15 2014-10-21 Aurora Algae, Inc. Systems and methods for extracting lipids from wet algal biomass
US9101942B2 (en) * 2009-06-16 2015-08-11 Aurora Algae, Inc. Clarification of suspensions
US8769867B2 (en) * 2009-06-16 2014-07-08 Aurora Algae, Inc. Systems, methods, and media for circulating fluid in an algae cultivation pond
US8747930B2 (en) * 2009-06-29 2014-06-10 Aurora Algae, Inc. Siliceous particles
US20100325948A1 (en) * 2009-06-29 2010-12-30 Mehran Parsheh Systems, methods, and media for circulating and carbonating fluid in an algae cultivation pond
CN101585759B (zh) * 2009-07-08 2012-05-23 内蒙古金达威药业有限公司 从双鞭甲藻发酵液中提取dha不饱和脂肪酸的方法
WO2011006144A1 (en) 2009-07-10 2011-01-13 Martek Biosciences Corporation Methods of treating and preventing neurological disorders using docosahexaenoic acid
US8709765B2 (en) * 2009-07-20 2014-04-29 Aurora Algae, Inc. Manipulation of an alternative respiratory pathway in photo-autotrophs
WO2011041710A2 (en) 2009-10-01 2011-04-07 Martek Biosciences Corporation Docosahexaenoic acid gel caps
US8765983B2 (en) * 2009-10-30 2014-07-01 Aurora Algae, Inc. Systems and methods for extracting lipids from and dehydrating wet algal biomass
US8748160B2 (en) * 2009-12-04 2014-06-10 Aurora Alage, Inc. Backward-facing step
US20110195449A1 (en) 2009-12-28 2011-08-11 Martek Biosciences Corporation Recombinant Thraustochytrids that Grow on Sucrose, and Compositions, Methods of Making, and Uses Thereof
ES2651313T3 (es) * 2009-12-28 2018-01-25 Dsm Ip Assets B.V. Traustoquítridos recombinantes que crecen en xilosa, y composiciones, métodos de preparación y usos de los mismos
MX343403B (es) * 2010-01-19 2016-11-03 Dsm Ip Assets B V * Microorganismos productores de acido eicosapentenoico, composiciones de acido graso, y metodos de elaboracion y usos de los mismos.
US8303818B2 (en) * 2010-06-24 2012-11-06 Streamline Automation, Llc Method and apparatus using an active ionic liquid for algae biofuel harvest and extraction
US8475660B2 (en) 2010-04-06 2013-07-02 Heliae Development, Llc Extraction of polar lipids by a two solvent method
US8273248B1 (en) 2010-04-06 2012-09-25 Heliae Development, Llc Extraction of neutral lipids by a two solvent method
WO2011127127A2 (en) 2010-04-06 2011-10-13 Arizona Board Of Regents For And On Behalf Of Arizona State University Extraction with fractionation of oil and co-products from oleaginous material
US8313648B2 (en) 2010-04-06 2012-11-20 Heliae Development, Llc Methods of and systems for producing biofuels from algal oil
US8115022B2 (en) 2010-04-06 2012-02-14 Heliae Development, Llc Methods of producing biofuels, chlorophylls and carotenoids
US8308951B1 (en) 2010-04-06 2012-11-13 Heliae Development, Llc Extraction of proteins by a two solvent method
US8202425B2 (en) 2010-04-06 2012-06-19 Heliae Development, Llc Extraction of neutral lipids by a two solvent method
BR112012025641A2 (pt) 2010-04-06 2019-09-24 Heliae Dev Llc métodos e sistemas para produzir biocombustíveis.
US8211309B2 (en) 2010-04-06 2012-07-03 Heliae Development, Llc Extraction of proteins by a two solvent method
US8211308B2 (en) 2010-04-06 2012-07-03 Heliae Development, Llc Extraction of polar lipids by a two solvent method
US10125331B2 (en) * 2010-04-29 2018-11-13 Advanced Energy Development Renewable oil refining processes
MX352746B (es) 2010-05-28 2017-12-06 Terravia Holdings Inc Aceites específicos producidos a partir de microorganismos heterótrofos recombinantes.
JP5911479B2 (ja) * 2010-06-01 2016-04-27 ディーエスエム アイピー アセッツ ビー．ブイ． 細胞からの脂質の抽出およびそれに由来する生産物
NL2004832C2 (en) * 2010-06-07 2011-12-08 Evodos B V Separating biomass from an aqueous medium.
US9023625B2 (en) 2010-06-14 2015-05-05 Io-Mega Holding Corporation Methods for production of algae derived oils
MA34468B1 (fr) 2010-07-26 2013-08-01 Sapphire Energy Inc Procédé pour récupérer des composés oléagineux à partir d'une biomasse
US9028696B2 (en) 2010-07-26 2015-05-12 Sapphire Energy, Inc. Process for the recovery of oleaginous compounds from biomass
US8906236B2 (en) 2010-07-26 2014-12-09 Sapphire Energy, Inc. Process for the recovery of oleaginous compounds and nutrients from biomass
BR112013006493A2 (pt) 2010-09-21 2016-07-26 Shell Int Research processo para separar uma mistura contendo um óleo microbiano e uma substância microbiana
SG10201509035WA (en) 2010-11-03 2015-12-30 Solazyme Inc Microbial Oils With Lowered Pour Points, Dielectric Fluids Produced Therefrom, And Related Methods
US20120329138A1 (en) 2010-12-23 2012-12-27 Shell Oil Company Process for separation of a mixture containing a microbial substance and a liquid
US8722359B2 (en) 2011-01-21 2014-05-13 Aurora Algae, Inc. Genes for enhanced lipid metabolism for accumulation of lipids
CN102617431B (zh) * 2011-01-28 2013-09-25 天津滨海索尔特生物技术中心有限公司 用无机碱提取盐藻中的β-胡萝卜素的方法
CN110066836A (zh) 2011-02-02 2019-07-30 柯碧恩生物技术公司 产自重组产油微生物的定制油
US8926844B2 (en) 2011-03-29 2015-01-06 Aurora Algae, Inc. Systems and methods for processing algae cultivation fluid
US8569530B2 (en) 2011-04-01 2013-10-29 Aurora Algae, Inc. Conversion of saponifiable lipids into fatty esters
US8440805B2 (en) 2011-04-28 2013-05-14 Aurora Algae, Inc. Algal desaturases
US8752329B2 (en) 2011-04-29 2014-06-17 Aurora Algae, Inc. Optimization of circulation of fluid in an algae cultivation pond
US9487716B2 (en) 2011-05-06 2016-11-08 LiveFuels, Inc. Sourcing phosphorus and other nutrients from the ocean via ocean thermal energy conversion systems
EP2705138B1 (en) 2011-05-06 2017-03-22 TerraVia Holdings, Inc. Genetically engineered microorganisms that metabolize xylose
US20140099684A1 (en) * 2011-05-26 2014-04-10 Council Of Scientific & Industrial Research Engine worthy fatty acid methyl ester (biodiesel) from naturally occuring marine microalgal mats and marine microalgae cultured in open salt pans together with value addition of co-products
FR2975705B1 (fr) * 2011-05-27 2014-12-26 Roquette Freres Procede d'extraction du squalene a partir de microalgues
US8365462B2 (en) 2011-05-31 2013-02-05 Heliae Development, Llc V-Trough photobioreactor systems
USD661164S1 (en) 2011-06-10 2012-06-05 Heliae Development, Llc Aquaculture vessel
USD682637S1 (en) 2011-06-10 2013-05-21 Heliae Development, Llc Aquaculture vessel
USD679965S1 (en) 2011-06-10 2013-04-16 Heliae Development, Llc Aquaculture vessel
CA2842374C (en) 2011-07-21 2019-03-05 Dsm Ip Assets B.V. Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof
BR122015020126B1 (pt) 2011-07-21 2022-03-03 Dsm Ip Assets B.V Composição contendo óleo microbiano diluído
WO2013024174A1 (en) 2011-08-18 2013-02-21 Dsm Ip Assets B.V. Dha triglyceride, dha free fatty acid, and dha ethyl ester emulsions, and methods of treating spinal cord injury
BR112014010347A2 (pt) 2011-11-01 2017-04-18 Dsm Ip Assets Bv óleo contendo ácido graxo poliinsaturado oxidativamente estável
WO2013075116A2 (en) 2011-11-17 2013-05-23 Heliae Development, Llc Omega 7 rich compositions and methods of isolating omega 7 fatty acids
CN103131529B (zh) * 2011-11-23 2016-02-24 丰益(上海)生物技术研发中心有限公司 一种提取微生物油脂的方法
SG10201702442RA (en) 2012-04-18 2017-05-30 Terravia Holdings Inc Tailored oils
WO2013166065A1 (en) 2012-04-30 2013-11-07 Aurora Algae, Inc. ACP Promoter
CN103421595A (zh) * 2012-05-25 2013-12-04 丰益(上海)生物技术研发中心有限公司 一种提取微生物油脂的方法
WO2014004999A1 (en) * 2012-06-29 2014-01-03 BP Biofuels UK Limited Process for separation of renewable materials from microorganisms
CN103589503B (zh) * 2012-08-13 2015-09-30 丰益(上海)生物技术研发中心有限公司 一种高效提取微生物油脂的方法
KR101470078B1 (ko) * 2012-08-21 2014-12-08 현대자동차주식회사 이산화탄소 포집ㆍ고정ㆍ전환을 통한 온실가스 감축 및 부가가치화 방법
US10098371B2 (en) 2013-01-28 2018-10-16 Solazyme Roquette Nutritionals, LLC Microalgal flour
US9567615B2 (en) 2013-01-29 2017-02-14 Terravia Holdings, Inc. Variant thioesterases and methods of use
US9816079B2 (en) 2013-01-29 2017-11-14 Terravia Holdings, Inc. Variant thioesterases and methods of use
WO2014122092A1 (de) * 2013-02-05 2014-08-14 Evonik Industries Ag Verbesserung der bioverfügbarkeit von wertstoffen aus mikroorganismen
EP2762009A1 (de) * 2013-02-05 2014-08-06 Evonik Industries AG Verbesserung der Bioverfügbarkeit von Wertstoffen aus Mikroorganismen
WO2014141098A1 (en) 2013-03-13 2014-09-18 Dsm Nutritional Products Ag Engineering microorganisms
US9783836B2 (en) 2013-03-15 2017-10-10 Terravia Holdings, Inc. Thioesterases and cells for production of tailored oils
US9290749B2 (en) 2013-03-15 2016-03-22 Solazyme, Inc. Thioesterases and cells for production of tailored oils
US9266973B2 (en) 2013-03-15 2016-02-23 Aurora Algae, Inc. Systems and methods for utilizing and recovering chitosan to process biological material
WO2014186395A1 (en) 2013-05-15 2014-11-20 Solazyme, Inc. Cosmetic compositions comprising microalgal oil
EP2826384A1 (de) 2013-07-16 2015-01-21 Evonik Industries AG Verfahren zur Trocknung von Biomasse
FR3009619B1 (fr) 2013-08-07 2017-12-29 Roquette Freres Compositions de biomasse de microalgues riches en proteines de qualite sensorielle optimisee
BR112016006839A8 (pt) 2013-10-04 2017-10-03 Solazyme Inc Óleos customizados
KR102143001B1 (ko) * 2013-11-01 2020-08-11 에스케이이노베이션 주식회사 초음속 분산기를 이용한 유질 미생물 파쇄 공정 및 이를 이용한 바이오 오일의 제조방법
MX383112B (es) 2013-12-20 2025-03-13 Dsm Ip Assets Bv Procedimientos para obtener aceite microbiano a partir de células microbianas.
MX391467B (es) 2013-12-20 2025-03-11 Dsm Ip Assets Bv Procedimiento para la obtención de aceite microbiano a partir de células microbianas.
KR102615285B1 (ko) 2013-12-20 2023-12-19 마라 리뉴어블즈 코퍼레이션 미생물로부터 오일을 회수하는 방법
EP3082792A4 (en) 2013-12-20 2017-08-16 DSM IP Assets B.V. Processes for obtaining microbial oil from microbial cells
CA2933995C (en) * 2013-12-20 2023-02-28 Dsm Nutritional Products Ag Methods of recovering oil from microorganisms
SG11201605066WA (en) * 2013-12-20 2016-07-28 Dsm Ip Assets Bv Processes for obtaining microbial oil from microbial cells
JP2017504318A (ja) 2013-12-20 2017-02-09 ディーエスエム アイピー アセッツ ビー．ブイ． 微生物細胞から微生物油を入手するための方法
ES2764273T3 (es) 2014-07-10 2020-06-02 Corbion Biotech Inc Nuevos genes de cetoacil ACP sintasa y uso de los mismos
CN107087416A (zh) 2014-07-24 2017-08-22 泰拉瑞亚控股公司 变体硫酯酶及使用方法
US10125382B2 (en) 2014-09-18 2018-11-13 Corbion Biotech, Inc. Acyl-ACP thioesterases and mutants thereof
CA2958439C (en) 2014-10-02 2022-09-20 Evonik Industries Ag Feedstuff of high abrasion resistance and good stability in water, containing pufas
DK3200606T3 (da) 2014-10-02 2021-06-21 Evonik Operations Gmbh Fremgangsmåde til fremstilling af et fodermiddel, der indeholder pufa'er, ved ekstrusion af en biomasse, der indeholder pufa'er, af typen labyrinthulomycetes
CN107075540A (zh) 2014-10-02 2017-08-18 赢创德固赛有限公司 用于制备具有高细胞稳定性的含pufa生物质的方法
BR112017005388B1 (pt) 2014-10-02 2022-09-13 Evonik Operations Gmbh Alimento para animais contendo biomassa de aurantiochytrium
EP3236927B1 (en) 2014-12-22 2019-11-13 Unilever PLC Hair composition
KR20160096478A (ko) * 2015-02-05 2016-08-16 주식회사 이코원 탄소 발열 모듈 및 이를 이용한 탄소 발열 튀김기
AR104042A1 (es) 2015-03-26 2017-06-21 Mara Renewables Corp Producción de alta densidad de biomasa y aceite utilizando glicerol en bruto
CN107567331A (zh) 2015-03-31 2018-01-09 费森尤斯卡比德国有限公司 用于肠胃外给药的乳液
US20160298104A1 (en) * 2015-04-07 2016-10-13 Decant Treatment Systems, Llc Method for electrical treatment of fluid medium containing biological matter and a system for its implementation
EP3297604B1 (en) 2015-05-22 2020-07-22 Fresenius Kabi Deutschland GmbH Vitamin a for parenteral administration
US10342775B2 (en) 2015-05-22 2019-07-09 Fresenius Kabi Deutschland Gmbh Vitamin A for parenteral administration
WO2017009790A1 (en) 2015-07-13 2017-01-19 MARA Renewables Corporation Enhancing microalgal metabolism of xylose
ITUB20152958A1 (it) 2015-08-06 2017-02-06 Eni Spa Metodo per concentrare una sospensione cellulare comprendente una biomassa mucillaginosa di lieviti oleaginosi.
KR102680258B1 (ko) * 2016-04-18 2024-07-02 서울바이오시스 주식회사 공기 청정기
CN109477079A (zh) 2016-05-12 2019-03-15 帝斯曼知识产权资产管理有限公司 增加微藻中ω-3多不饱和脂肪酸产量的方法
US10851395B2 (en) 2016-06-10 2020-12-01 MARA Renewables Corporation Method of making lipids with improved cold flow properties
US11419350B2 (en) 2016-07-01 2022-08-23 Corbion Biotech, Inc. Feed ingredients comprising lysed microbial cells
WO2018013670A1 (en) * 2016-07-13 2018-01-18 Dsm Ip Assets B.V. Method for extracting a microbial oil comprising polyunsaturated fatty acids from a fermentation broth containing oleaginous microorganisms
US11946017B2 (en) 2016-07-13 2024-04-02 Evonik Operations Gmbh Method of separating lipids from a lysed lipids containing biomass
WO2018069145A1 (en) 2016-10-11 2018-04-19 Fresenius Kabi Deutschland Gmbh Composition comprising epa and dha for an enhanced efficacy of anticancer agents
WO2018122057A1 (en) * 2016-12-27 2018-07-05 Evonik Degussa Gmbh Method of isolating lipids from a lipids containing biomass
WO2019034354A1 (en) 2017-08-17 2019-02-21 Evonik Degussa Gmbh ENHANCED PRODUCTION OF LIPIDS BY LIMITING AT LEAST TWO SOURCES OF NUTRIENT LIMITING
US11814665B2 (en) 2017-08-17 2023-11-14 Evonik Operations Gmbh Enhanced production of lipids by limitation of at least two limiting nutrient sources
EP3470502A1 (en) * 2017-10-13 2019-04-17 Evonik Degussa GmbH Method of separating lipids from a lysed lipids containing biomass
EP3527664A1 (en) 2018-02-15 2019-08-21 Evonik Degussa GmbH Method of isolating lipids from a lipids containing biomass
WO2019122030A1 (en) * 2017-12-22 2019-06-27 Dsm Ip Assets B.V. Method of separating lipids from a lysed lipids containing biomass
EP3775118A4 (en) * 2018-03-30 2022-03-09 DSM IP Assets B.V. Method of reducing emulsion by broth washing
WO2019191544A1 (en) * 2018-03-30 2019-10-03 Dsm Ip Assets B.V. Method of obtaining a microbial oil and a method of reducing emulsion by maintaining a low concentration of carbohydrate
WO2019219396A1 (en) 2018-05-15 2019-11-21 Evonik Operations Gmbh Method of isolating lipids from a lysed lipids containing biomass by emulsion inversion
WO2019219443A1 (en) 2018-05-15 2019-11-21 Evonik Operations Gmbh Method of isolating lipids from a lipids containing biomass with aid of hydrophobic silica
BR112020023199A2 (pt) 2018-07-03 2021-04-13 Fresenius Kabi Deutschland Gmbh Emulsão de lípidos para administração parenteral
FR3085962B1 (fr) 2018-09-14 2021-06-18 Fermentalg Procede d'extracton d'une huile riche en pufa
FR3085825B1 (fr) 2018-09-14 2021-07-16 Fermentalg Huile de microorganismes riche en acide docosahexaenoique
US20220017930A1 (en) * 2018-11-09 2022-01-20 Evonik Operations Gmbh Method for producing a biomass which can be easily broken down and which has an increased content of polyunsaturated fatty acids
CN112969796B (zh) 2018-11-09 2025-02-07 赢创运营有限公司 用于生产具有增加的多不饱和脂肪酸含量的生物质的方法
JP7550755B2 (ja) * 2018-12-14 2024-09-13 ディーエスエム アイピー アセッツ ビー．ブイ． 向上された嗜好性を有する多価不飽和脂肪酸含有食品成分及びそれを製造する方法
WO2020186128A1 (en) 2019-03-14 2020-09-17 Dsm Ip Assets B.V. Methods of obtaining lipids from a microbial cell composition
US20230054162A1 (en) 2019-12-20 2023-02-23 Fresenius Kabi Austria Gmbh Methods for producing oil-in-water emulsions
CN111235035A (zh) * 2019-12-30 2020-06-05 嘉必优生物技术（武汉）股份有限公司 一种裂殖壶菌突变株及其用于制备二十二碳六烯酸油脂的方法和应用
KR20220163979A (ko) 2020-04-03 2022-12-12 마라 리뉴어블즈 코퍼레이션 높은 수준의 오메가-3 지방산을 갖는 미생물 오일
FR3111912B1 (fr) 2020-06-24 2025-10-03 Fermentalg Procédé de culture de microorganismes pour l’accumulation de lipides
FR3130842B1 (fr) 2021-12-22 2025-06-27 CarbonWorks Procede de captation des phytotoxines dans un reacteur biologique
KR102795205B1 (ko) * 2022-01-27 2025-04-10 씨제이제일제당 (주) 냉각 공정을 이용한 오일 회수율이 향상된 바이오오일 추출 방법
EP4493707A1 (en) * 2022-03-18 2025-01-22 Purac Biochem B.V. Method for reducing fermentation broth viscosity
WO2023220060A1 (en) * 2022-05-11 2023-11-16 C16 Biosciences, Inc. Enzymatic lysis for extraction of bioproducts from yeast
US20240216321A1 (en) 2022-12-02 2024-07-04 Dsm Ip Assets B.V. Fermentatively-produced retinoid containing compositions, and the methdos of making and using the same
KR20240109876A (ko) * 2023-01-05 2024-07-12 주식회사 밤비콜라 커피박을 이용한 칸디다 봄비콜라의 배양방법 및 이로부터의 배양물
CN117210270A (zh) * 2023-09-05 2023-12-12 吴善艳 一种从微生物物质无溶剂萃取含有dha油脂的方法

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU358359A1 (ru) * Иа 1
SU362870A1 (ru) * 1971-02-25 1972-12-30 Всесоюзный научно исследовательский институт биосинтеза белковых веществ Способ получения липидов
SU839258A1 (ru) * 1979-03-22 1983-08-07 Всесоюзный научно-исследовательский институт биосинтеза белковых веществ Способ получени липидов
SU1102276A1 (ru) * 1983-01-28 1985-03-07 Всесоюзный Научно-Исследовательский Институт Биосинтеза Белковых Веществ Главного Управления Микробиологической Промышленности Способ получени липидов
US5179012A (en) * 1990-01-11 1993-01-12 Commissariat A L'energie Atomique Process for the production and extraction of antioxidants from a micro-organism culture
US5928696A (en) * 1994-08-16 1999-07-27 Dr. Frische Gmbh Process for extracting native products which are not water-soluble from native substance mixtures by centrifugal force

Family Cites Families (121)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2753362A (en) * 1951-05-18 1956-07-03 Standard Brands Inc Process of extracting lipids from plant and animal tissue
GB808128A (en) * 1955-12-01 1959-01-28 Nat Res Dev A method of increasing the fatty contents of such micro-organisms as yeasts, bacteria and moulds
US3089821A (en) * 1959-10-28 1963-05-14 Merck & Co Inc Process for the preparation of lipids
DE2056896B2 (de) * 1970-02-18 1979-12-06 Veb Schwermaschinenbau Kombinat Ernst Thaelmann Magdeburg, Ddr 3011 Magdeburg Verfahren zur gleichzeitigen Gewinnung von Fett und Protein aus pflanzlichen, ölhaltigen Rohstoffen und Zwischenprodukten
US3878232A (en) * 1970-09-28 1975-04-15 Staley Mfg Co A E Extraction process to improve the quality and yield of crude vegetable oils
US4504473A (en) * 1982-06-30 1985-03-12 Ribi Immunochem Research, Inc. Pyridine soluble extract of a microorganism
DE3248167A1 (de) * 1982-12-27 1984-06-28 Wintershall Ag, 3100 Celle Trehaloselipidtetraester
US4792418A (en) * 1985-08-14 1988-12-20 Century Laboratories, Inc. Method of extraction and purification of polyunsaturated fatty acids from natural sources
JPS6244170A (ja) 1985-08-19 1987-02-26 Agency Of Ind Science & Technol モルテイエレラ属糸状菌体の超臨界流体による抽出方法
US4680314A (en) 1985-08-30 1987-07-14 Microbio Resources, Inc. Process for producing a naturally-derived carotene/oil composition by direct extraction from algae
JPH0634730B2 (ja) * 1986-06-16 1994-05-11 鐘淵化学工業株式会社 パルミトレイン酸の製造法
DK199887D0 (da) 1987-04-15 1987-04-15 Danisco Bioteknologi As Gaerstamme
FR2621327B1 (fr) 1987-10-06 1990-01-05 Commissariat Energie Atomique Procede de production et d'extraction de polysaccharides a partir d'une culture de porphyridium cruentum et dispositif pour la mise en oeuvre du procede
JPH0198494A (ja) 1987-10-09 1989-04-17 Agency Of Ind Science & Technol バイオリアクター
US5340742A (en) 1988-09-07 1994-08-23 Omegatech Inc. Process for growing thraustochytrium and schizochytrium using non-chloride salts to produce a microfloral biomass having omega-3-highly unsaturated fatty acids
US6451567B1 (en) 1988-09-07 2002-09-17 Omegatech, Inc. Fermentation process for producing long chain omega-3 fatty acids with euryhaline microorganisms
US5340594A (en) 1988-09-07 1994-08-23 Omegatech Inc. Food product having high concentrations of omega-3 highly unsaturated fatty acids
US5130242A (en) * 1988-09-07 1992-07-14 Phycotech, Inc. Process for the heterotrophic production of microbial products with high concentrations of omega-3 highly unsaturated fatty acids
US5173409A (en) 1989-12-08 1992-12-22 Ecogen Inc. Recovery of bt endotoxin protein from lysed cell mixtures
US5407957A (en) 1990-02-13 1995-04-18 Martek Corporation Production of docosahexaenoic acid by dinoflagellates
US5658767A (en) 1991-01-24 1997-08-19 Martek Corporation Arachidonic acid and methods for the production and use thereof
US6270828B1 (en) 1993-11-12 2001-08-07 Cargrill Incorporated Canola variety producing a seed with reduced glucosinolates and linolenic acid yielding an oil with low sulfur, improved sensory characteristics and increased oxidative stability
FR2686619B1 (fr) * 1992-01-28 1995-07-13 Commissariat Energie Atomique Procede de production selective de lipides poly-insatures a partir d'une culture de micro-algues du type porphyridium et cuve utilisee dans ce procede.
US5476787A (en) 1992-04-24 1995-12-19 Director-General Of Agency Of Industrial Science And Technology Method of removing nitrogen impurities from water using hydrocarbon-producing microalga
DE4219360C2 (de) * 1992-06-12 1994-07-28 Milupa Ag Verfahren zur Gewinnung von Lipiden mit einem hohen Anteil von langkettig-hochungesättigten Fettsäuren
JPH072724A (ja) * 1993-03-24 1995-01-06 Nippon Sanso Kk １３ｃ標識アラキドン酸とその誘導体及び製造方法
JPH06340577A (ja) * 1993-03-24 1994-12-13 Nippon Sanso Kk １３ｃ標識イコサペンタエン酸とその誘導体及び製造方法
FR2719222B1 (fr) * 1994-05-02 1996-06-21 Rocher Yves Biolog Vegetale Vésicules lipidiques, leur procédé de fabrication et leurs applications.
US5583019A (en) 1995-01-24 1996-12-10 Omegatech Inc. Method for production of arachidonic acid
JP2764572B2 (ja) * 1995-04-17 1998-06-11 工業技術院長 ドコサヘキサエン酸生産能を有する新規微生物及びそれを用いたドコサヘキサエン酸の製造方法
US6582941B1 (en) 1995-04-17 2003-06-24 Japan As Represented By Director-General Of Agency Of Industrial Science And Technology Microorganisms capable of producing highly unsaturated fatty acids and process for producing highly unsaturated fatty acids by using the microorganisms
ES2130515T3 (es) * 1995-05-04 1999-07-01 Nestle Sa Procedimiento para fraccionar acidos grasos.
GB9514649D0 (en) 1995-07-18 1995-09-13 Zeneca Ltd Extraction of triglycerides from microorganisms
JP3985035B2 (ja) * 1995-09-14 2007-10-03 独立行政法人産業技術総合研究所 （ｎ−６）系ドコサペンタエン酸含有油脂ならびに該油脂の製造方法および用途
US6255505B1 (en) 1996-03-28 2001-07-03 Gist-Brocades, B.V. Microbial polyunsaturated fatty acid containing oil from pasteurised biomass
WO1998001536A1 (en) 1996-07-03 1998-01-15 Sagami Chemical Research Center Microorganisms producing docosahexaenoic acid and process for the production of docosahexaenoic acid
US6509178B1 (en) * 1996-07-23 2003-01-21 Suntory Ltd. Process for preparing docosahexaenoic acid and docosapentaenoic acid with ulkenia
US5951875A (en) 1996-12-20 1999-09-14 Eastman Chemical Company Adsorptive bubble separation methods and systems for dewatering suspensions of microalgae and extracting components therefrom
EP0972844B1 (en) * 1997-03-04 2008-09-17 Suntory Limited Process for preparing highly unsaturated fatty acid and lipid containing highly unsaturated fatty acid
DE69841382D1 (de) 1997-05-02 2010-01-28 Dsm Ip Assets Bv Isolierung von carotenoiden kristallen aus mikrobieller biomasse
US7585645B2 (en) 1997-05-27 2009-09-08 Sembiosys Genetics Inc. Thioredoxin and thioredoxin reductase containing oil body based products
EP1905309A1 (en) 1997-05-27 2008-04-02 SemBioSys Genetics Inc. Uses of oil bodies
US6566583B1 (en) 1997-06-04 2003-05-20 Daniel Facciotti Schizochytrium PKS genes
JP3836231B2 (ja) * 1997-10-17 2006-10-25 日本化学飼料株式会社 ホタテガイ中腸腺から得られる高度不飽和脂肪酸含有油及びその製造方法
US6528941B1 (en) 1997-11-12 2003-03-04 Mitsubishi Denki Kabushiki Kaisha Electroluminescent device and shield therefor
JP2000041684A (ja) 1998-07-29 2000-02-15 Daicel Chem Ind Ltd 新規なｄ−アミノアシラーゼおよびその製造方法、並びに該ｄ−アミノアシラーゼを利用したｄ−アミノ酸の製造方法
FR2782921B1 (fr) 1998-09-09 2002-09-20 Dior Christian Parfums Extrait lipidique de l'algue skeletonema, procede de preparation et utilisation dans des domaines cosmetique et pharmaceutique, notamment dermatologique
US6166231A (en) 1998-12-15 2000-12-26 Martek Biosciences Corporation Two phase extraction of oil from biomass
JP2000245492A (ja) 1999-03-02 2000-09-12 Kyowa Hakko Kogyo Co Ltd 微生物抽出脂質
US6344349B1 (en) 1999-12-06 2002-02-05 Decant Technologies Llc Process and system for electrical extraction of intracellular matter from biological matter
RU2336307C2 (ru) * 2000-01-19 2008-10-20 Мартек Биосайнсис Корпорейшн Способ получения липидов (варианты) и липиды, полученные этим способом
DE10018213A1 (de) 2000-04-12 2001-10-25 Westfalia Separator Ind Gmbh Verfahren zur Fraktionierung von öl-und lecithinhaltigen nativen Rohstoffen
EP1272049B1 (en) 2000-04-12 2009-11-04 GEA Westfalia Separator GmbH Method for the fractionation of oil and polar lipid-containing native raw materials using alcohol and centrifugation
EP1178118A1 (en) 2000-08-02 2002-02-06 Dsm N.V. Isolation of microbial oils
US20060060520A1 (en) 2001-06-25 2006-03-23 Bomberger David C Systems and methods using a solvent for the removal of lipids from fluids
WO2003017945A2 (en) 2001-08-24 2003-03-06 Martek Biosciences Boulder Corporation Products containing highly unsaturated fatty acids for use by women and their children during stages of preconception, pregnancy and lactation/post-partum
US7419596B2 (en) 2001-12-12 2008-09-02 Martek Biosciences Corporation Extraction and winterization of lipids from oilseed and microbial sources
WO2003092628A2 (en) 2002-05-03 2003-11-13 Martek Biosciences Corporation High-quality lipids and methods for producing by enzymatic liberation from biomass
KR102254453B1 (ko) 2002-06-19 2021-05-21 디에스엠 아이피 어셋츠 비.브이. 미생물 세포와 미생물 오일용 파스퇴르살균 방법
EP2759599A3 (en) 2003-10-02 2014-12-10 DSM IP Assets B.V. Production of high levels of DHA in microalgae using modified amounts of chloride and potassium
CN1954079B (zh) 2004-03-01 2012-08-08 三得利控股株式会社 含有作为构成要素的长链高不饱和脂肪酸的磷脂质的制造方法及其应用
JP2007534335A (ja) 2004-04-27 2007-11-29 バクスター・インターナショナル・インコーポレイテッド 攪拌タンク反応器システム
EP1597976B1 (en) 2004-05-21 2013-01-30 Nestec S.A. Use of polyol esters of fatty acids in aerated frozen confection with improved nutritional attributes
DE102004062141A1 (de) 2004-12-23 2006-07-06 Nutrinova Nutrition Specialties & Food Ingredients Gmbh Verfahren zur Herstellung eines Rohöls aus Gemischen von Mikroorganismen und Pflanzen, das so hergestellte Öl sowie die spezifischen Verwendungen des so hergestellten und gegebenenfalls zusätzlich raffinierten Öls
DE102005003624A1 (de) 2005-01-26 2006-07-27 Nutrinova Nutrition Specialties & Food Ingredients Gmbh Herstellung und Anwendung eines antioxidativ wirksamen Extraktes aus Crypthecodinium sp.
NZ563125A (en) 2005-06-03 2009-11-27 Mcfarlane Marketing Aust Pty L Lipid extract of mussels and method for preparation thereof
EP1899453B1 (en) 2005-06-07 2013-12-18 Ocean Nutrition Canada Limited Eukaryotic microorganisms for producing lipids and antioxidants
WO2007005725A2 (en) 2005-07-01 2007-01-11 Martek Biosciences Corporation Polyunsaturated fatty acid-containing oil product and uses and production thereof
US7527734B1 (en) 2005-11-15 2009-05-05 Shepherd Samuel L Rapid non-equilibrium decompression of microorganism-containing waste streams
US20070213298A1 (en) 2006-02-07 2007-09-13 Universitetet I Oslo Omega 3
WO2008004900A1 (en) 2006-07-05 2008-01-10 Photonz Corporation Limited Production of ultrapure epa and polar lipids from largely heterotrophic culture
EP1887011A1 (en) 2006-08-09 2008-02-13 Thermphos Trading GmbH Alpha amino acid phosphonic acid compounds, method of preparation and use thereof
EP2074214A2 (en) 2006-09-28 2009-07-01 Microbia, Inc. Production of sterols in oleaginous yeast and fungi
US20080083352A1 (en) 2006-10-10 2008-04-10 Ernest Peter Tovani Vehicle Table System
KR100810314B1 (ko) 2006-10-11 2008-03-04 삼성전자주식회사 휴대 단말기의 키 입력 장치
US8088614B2 (en) 2006-11-13 2012-01-03 Aurora Algae, Inc. Methods and compositions for production and purification of biofuel from plants and microalgae
EP2097496B1 (en) 2006-12-01 2010-12-29 The North Carolina State University Process for conversion of biomass to fuel
WO2008088489A2 (en) 2006-12-22 2008-07-24 Danisco Us, Inc., Genencor Division Enzyme-assisted de-emulsification of aqueous lipid extracts
EP2160089A1 (en) 2007-06-14 2010-03-10 Nickolaos Mitropoulos Algae growth for biofuels
US20100226977A1 (en) 2007-08-29 2010-09-09 Aker Biomarine Asa Low viscosity phospholipid compositions
BRPI0815860B1 (pt) 2007-09-12 2021-04-20 Dsm Ip Assets B.V. métodos para produzir um óleo biológico
JP4594998B2 (ja) * 2008-05-21 2010-12-08 株式会社日立製作所 エレベーターかごの速度検出装置の検査方法。
ITMI20081203A1 (it) 2008-06-30 2010-01-01 Eni Spa Procedimento per l'estrazione di acidi grassi da biomassa algale
EP2145942A1 (de) 2008-07-15 2010-01-20 Lonza Ltd. Verfahren zur Isolierung von Ölen aus Zellen und Biomasse
CN102186966A (zh) 2008-08-04 2011-09-14 凯生物能公司 光合培养物的连续培养、收获和油提取
EP2337857B1 (en) 2008-10-02 2017-02-22 Nieves Gonzalez Ramon Microalgae extract containing 3 -polyunsaturated fatty acids and method for extracting oil from micro-organisms
CN104770424A (zh) 2008-10-14 2015-07-15 索拉兹米公司 微藻生物质的食品组合物
SE534278C2 (sv) 2009-02-17 2011-06-28 Alfa Laval Corp Ab Ett kontinuerligt förfarande för isolering av oljor från alger eller mikroorganismer
US9296985B2 (en) 2009-03-10 2016-03-29 Valicor, Inc. Algae biomass fractionation
US8207363B2 (en) 2009-03-19 2012-06-26 Martek Biosciences Corporation Thraustochytrids, fatty acid compositions, and methods of making and uses thereof
US8476060B2 (en) 2009-04-13 2013-07-02 Board Of Regents, The University Of Texas System Process for separating lipids from a biomass
BRPI1012026A2 (pt) 2009-05-26 2018-07-17 Solazyme Inc fracionamento de biomassa microbiana contendo óleo
KR101659765B1 (ko) 2009-09-28 2016-09-27 삼성전자주식회사 다중 모드 휴대용 단말기에서 전력 소모를 줄이기 위한 장치 및 방법
WO2011130576A1 (en) 2010-04-14 2011-10-20 Solazyme, Inc. Oleaginous yeast food compositions
JP5911479B2 (ja) 2010-06-01 2016-04-27 ディーエスエム アイピー アセッツ ビー．ブイ． 細胞からの脂質の抽出およびそれに由来する生産物
US9023625B2 (en) 2010-06-14 2015-05-05 Io-Mega Holding Corporation Methods for production of algae derived oils
US9028696B2 (en) 2010-07-26 2015-05-12 Sapphire Energy, Inc. Process for the recovery of oleaginous compounds from biomass
MA34468B1 (fr) 2010-07-26 2013-08-01 Sapphire Energy Inc Procédé pour récupérer des composés oléagineux à partir d'une biomasse
EP2600957A4 (en) 2010-08-06 2017-11-08 ICM, Inc. Bio-oil recovery systems and methods
US20120040428A1 (en) 2010-08-13 2012-02-16 Paul Reep Procedure for extracting of lipids from algae without cell sacrifice
US20120129244A1 (en) 2010-10-17 2012-05-24 Michael Phillip Green Systems, methods and apparatuses for dewatering, flocculating and harvesting algae cells
CN101985637B (zh) 2010-11-02 2014-05-07 嘉必优生物工程（武汉）有限公司 一种微生物油脂的提取方法
PT2450425E (pt) 2010-11-08 2014-07-24 Neste Oil Oyj Um método para a extração de lípidos a partir de biomassa
AU2012214187A1 (en) 2011-02-12 2013-05-02 Phycal, Inc. Aqueous extraction methods for high lipid microorganisms
AU2012226528B2 (en) 2011-03-07 2015-08-20 Dsm Nutritional Products Ag Engineering thraustochytrid microorganisms
US20120238732A1 (en) 2011-03-15 2012-09-20 Iowa State University Research Foundation, Inc. Oil extraction from microalgae
FR2975705B1 (fr) 2011-05-27 2014-12-26 Roquette Freres Procede d'extraction du squalene a partir de microalgues
CN102433215A (zh) 2011-09-22 2012-05-02 厦门汇盛生物有限公司 一种从真菌或藻类中物理破壁提取油脂的方法
CN102388988B (zh) 2011-11-08 2013-01-23 中国农业科学院油料作物研究所 一种微生物油的分提方法
WO2013075116A2 (en) 2011-11-17 2013-05-23 Heliae Development, Llc Omega 7 rich compositions and methods of isolating omega 7 fatty acids
US9346722B2 (en) 2012-04-16 2016-05-24 Roquette Freres Method for refining squalene produced by microalgae
WO2014004999A1 (en) 2012-06-29 2014-01-03 BP Biofuels UK Limited Process for separation of renewable materials from microorganisms
KR102615285B1 (ko) 2013-12-20 2023-12-19 마라 리뉴어블즈 코퍼레이션 미생물로부터 오일을 회수하는 방법
MX383112B (es) 2013-12-20 2025-03-13 Dsm Ip Assets Bv Procedimientos para obtener aceite microbiano a partir de células microbianas.
SG11201605066WA (en) 2013-12-20 2016-07-28 Dsm Ip Assets Bv Processes for obtaining microbial oil from microbial cells
EP3082792A4 (en) 2013-12-20 2017-08-16 DSM IP Assets B.V. Processes for obtaining microbial oil from microbial cells
JP2017504318A (ja) 2013-12-20 2017-02-09 ディーエスエム アイピー アセッツ ビー．ブイ． 微生物細胞から微生物油を入手するための方法
MX391467B (es) 2013-12-20 2025-03-11 Dsm Ip Assets Bv Procedimiento para la obtención de aceite microbiano a partir de células microbianas.
CN106062160A (zh) 2013-12-20 2016-10-26 帝斯曼知识产权资产管理有限公司 提取用于生产生物燃料的脂质的方法
CA2933995C (en) 2013-12-20 2023-02-28 Dsm Nutritional Products Ag Methods of recovering oil from microorganisms
HRP20240128T1 (hr) 2014-07-07 2024-04-12 Nuseed Global Innovation Ltd Postupci za proizvodnju industrijskih proizvoda iz biljnih lipida

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU358359A1 (ru) * Иа 1
SU362870A1 (ru) * 1971-02-25 1972-12-30 Всесоюзный научно исследовательский институт биосинтеза белковых веществ Способ получения липидов
SU839258A1 (ru) * 1979-03-22 1983-08-07 Всесоюзный научно-исследовательский институт биосинтеза белковых веществ Способ получени липидов
SU1102276A1 (ru) * 1983-01-28 1985-03-07 Всесоюзный Научно-Исследовательский Институт Биосинтеза Белковых Веществ Главного Управления Микробиологической Промышленности Способ получени липидов
US5179012A (en) * 1990-01-11 1993-01-12 Commissariat A L'energie Atomique Process for the production and extraction of antioxidants from a micro-organism culture
US5928696A (en) * 1994-08-16 1999-07-27 Dr. Frische Gmbh Process for extracting native products which are not water-soluble from native substance mixtures by centrifugal force

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2605328C2 (ru) * 2011-02-16 2016-12-20 Соликс Алгредиентс, Инк. Композиция, набор и способ извлечения целевых соединений из биомассы
RU2744913C2 (ru) * 2016-12-27 2021-03-17 Эвоник Оперейшенс ГмбХ Способ выделения липидов из липидсодержащей биомассы
RU2776914C1 (ru) * 2018-11-09 2022-07-28 Эвоник Оперейшенс ГмбХ Способ получения биомассы, которая может легко расщепляться и которая характеризуется повышенным содержанием полиненасыщенных жирных кислот
RU2779882C1 (ru) * 2018-11-09 2022-09-14 Эвоник Оперейшенс ГмбХ Способ получения биомассы с повышенным содержанием полиненасыщенных жирных кислот

Also Published As

Publication number Publication date
EP2302065A1 (en) 2011-03-30
US7662598B2 (en) 2010-02-16
JP2015133969A (ja) 2015-07-27
ATE485385T1 (de) 2010-11-15
CA2397655C (en) 2012-06-05
KR20140079870A (ko) 2014-06-27
US20140212936A1 (en) 2014-07-31
NO20023449D0 (no) 2002-07-18
KR101429236B1 (ko) 2014-08-12
HUP0300556A3 (en) 2010-03-29
MX350779B (es) 2017-09-18
PL356587A1 (en) 2004-06-28
AU2012200890B2 (en) 2014-07-31
CA2772540A1 (en) 2001-07-26
IL150772A (en) 2010-06-16
JP2013099365A (ja) 2013-05-23
KR20130032395A (ko) 2013-04-01
KR20030013367A (ko) 2003-02-14
AU2012200890A1 (en) 2012-03-08
EP2295594A1 (en) 2011-03-16
NO20023449L (no) 2002-09-17
PT1252324E (pt) 2010-12-16
CN101463371A (zh) 2009-06-24
MX232239B (es) 2005-11-18
KR20150020609A (ko) 2015-02-26
JP5756137B2 (ja) 2015-07-29
IL201756A (en) 2011-06-30
IL150772A0 (en) 2003-02-12
KR100995575B1 (ko) 2010-11-19
ES2735987T3 (es) 2019-12-23
JP5722536B2 (ja) 2015-05-20
AU2005202980C1 (en) 2009-04-02
US20040229325A1 (en) 2004-11-18
KR20120070588A (ko) 2012-06-29
KR20100051131A (ko) 2010-05-14
ES2675517T3 (es) 2018-07-11
IL206961A (en) 2011-11-30
AU2014203384B2 (en) 2016-03-03
AU2018200956A1 (en) 2018-03-01
HUP0300556A2 (hu) 2003-06-28
BR0107699B1 (pt) 2014-05-27
EP2295595A1 (en) 2011-03-16
EP1252324A1 (en) 2002-10-30
MX275361B (en) 2010-04-21
US20080044876A1 (en) 2008-02-21
AU2014203384A1 (en) 2014-07-10
JP4020642B2 (ja) 2007-12-12
US20080044875A1 (en) 2008-02-21
EP2295594B1 (en) 2018-04-04
CN100460513C (zh) 2009-02-11
KR20110000592A (ko) 2011-01-03
JP2005278650A (ja) 2005-10-13
EP1252324B1 (en) 2010-10-20
AU2005202980B2 (en) 2008-07-10
JP2003520046A (ja) 2003-07-02
IL206960A0 (en) 2010-12-30
ES2352001T3 (es) 2011-02-14
KR101591834B1 (ko) 2016-02-18
AU2005202980A1 (en) 2005-08-04
US20170298288A1 (en) 2017-10-19
NZ520287A (en) 2004-01-30
AU2016203318A1 (en) 2016-06-09
US7351558B2 (en) 2008-04-01
US6750048B2 (en) 2004-06-15
RU2002119551A (ru) 2004-02-20
US20020001833A1 (en) 2002-01-03
KR20080007279A (ko) 2008-01-17
JP2010051328A (ja) 2010-03-11
CZ303446B6 (cs) 2012-09-19
US10329515B2 (en) 2019-06-25
KR101429238B1 (ko) 2014-08-12
US7781193B2 (en) 2010-08-24
DK1252324T3 (da) 2010-12-20
ZA200205790B (en) 2003-07-28
MX297659B (en) 2012-03-29
AU2963601A (en) 2001-07-31
US20190256797A1 (en) 2019-08-22
CA2397655A1 (en) 2001-07-26
KR101180462B1 (ko) 2012-09-06
MXPA02007092A (es) 2003-02-24
AU780619B2 (en) 2005-04-07
JP4537887B2 (ja) 2010-09-08
US20080038800A1 (en) 2008-02-14
US9738851B2 (en) 2017-08-22
WO2001053512A1 (en) 2001-07-26
DE60143287D1 (de) 2010-12-02
EP2295595B1 (en) 2019-05-01
BR0107699A (pt) 2003-01-14
CN1416469A (zh) 2003-05-07
EP1252324A4 (en) 2005-02-09
HK1050716A1 (en) 2003-07-04
AU2019226124A1 (en) 2019-09-26
NO20110858L (no) 2002-09-17

Similar Documents

Publication Publication Date Title
RU2336307C2 (ru) Способ получения липидов (варианты) и липиды, полученные этим способом
AU2008229885B2 (en) Solventless extraction process
HK1151319A (en) Solventless extraction process
HK1154906A (en) Solventless extraction process
HK1050716B (en) Solventless extraction process
HK1154907A (en) Solventless extraction process
HK1151319B (en) Solventless extraction process
HK1154906B (en) Solventless extraction process

Legal Events

Date Code Title Description
PC41 Official registration of the transfer of exclusive right

Effective date: 20130717