PE20021006A1 - Derivados de 3-(4-amidopirrol-2-ilmetiliden)-2-indolinona como inhibidores de la proteinquinasa - Google Patents

Derivados de 3-(4-amidopirrol-2-ilmetiliden)-2-indolinona como inhibidores de la proteinquinasa

Info

Publication number
PE20021006A1
PE20021006A1 PE2002000134A PE2002000134A PE20021006A1 PE 20021006 A1 PE20021006 A1 PE 20021006A1 PE 2002000134 A PE2002000134 A PE 2002000134A PE 2002000134 A PE2002000134 A PE 2002000134A PE 20021006 A1 PE20021006 A1 PE 20021006A1
Authority
PE
Peru
Prior art keywords
alkyl
ilmetiliden
amidopyrrol
indolinone
inhibitors
Prior art date
Application number
PE2002000134A
Other languages
English (en)
Spanish (es)
Inventor
Huiping Guan
Li Sun
Congxin Liang
Peng Cho Tang
Chung Chen Wei
Tomas Vojkovsky
Qingwu Jin
Paul Matthew Herrinton
Michael A Mauragis
Original Assignee
Sugen Inc
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sugen Inc, Upjohn Co filed Critical Sugen Inc
Publication of PE20021006A1 publication Critical patent/PE20021006A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PE2002000134A 2001-02-15 2002-02-15 Derivados de 3-(4-amidopirrol-2-ilmetiliden)-2-indolinona como inhibidores de la proteinquinasa PE20021006A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26868301P 2001-02-15 2001-02-15
US31236101P 2001-08-15 2001-08-15

Publications (1)

Publication Number Publication Date
PE20021006A1 true PE20021006A1 (es) 2002-11-08

Family

ID=26953263

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2002000134A PE20021006A1 (es) 2001-02-15 2002-02-15 Derivados de 3-(4-amidopirrol-2-ilmetiliden)-2-indolinona como inhibidores de la proteinquinasa

Country Status (40)

Country Link
US (4) US6653308B2 (enExample)
EP (1) EP1370554B1 (enExample)
JP (1) JP3677501B2 (enExample)
KR (1) KR100884858B1 (enExample)
CN (1) CN100338059C (enExample)
AP (1) AP1718A (enExample)
AR (1) AR042586A1 (enExample)
AT (1) ATE307128T1 (enExample)
AU (1) AU2002247133B2 (enExample)
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BR (1) BR0207494A (enExample)
CA (1) CA2438314C (enExample)
CR (1) CR7056A (enExample)
CZ (1) CZ20032414A3 (enExample)
DE (1) DE60206736T2 (enExample)
DK (1) DK1370554T3 (enExample)
EA (1) EA007186B1 (enExample)
EE (1) EE200300385A (enExample)
ES (1) ES2251580T3 (enExample)
GE (1) GEP20053600B (enExample)
HR (1) HRP20030657B1 (enExample)
HU (1) HUP0303146A3 (enExample)
IL (2) IL157418A0 (enExample)
IS (1) IS2411B (enExample)
MA (1) MA26997A1 (enExample)
MX (1) MXPA03007367A (enExample)
MY (1) MY126235A (enExample)
NO (1) NO326604B1 (enExample)
NZ (1) NZ527572A (enExample)
OA (1) OA12834A (enExample)
PE (1) PE20021006A1 (enExample)
PL (1) PL364176A1 (enExample)
RS (1) RS51026B (enExample)
SI (1) SI1370554T1 (enExample)
SK (1) SK11332003A3 (enExample)
TN (1) TNSN03055A1 (enExample)
TW (1) TWI324155B (enExample)
UA (1) UA75635C2 (enExample)
WO (1) WO2002066463A1 (enExample)
ZA (2) ZA200306335B (enExample)

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