YU71703A - Derivati 3-(4-amidopirol-2-ilmetiliden)-2-indolinona kao inhibitori protein kinaze - Google Patents
Derivati 3-(4-amidopirol-2-ilmetiliden)-2-indolinona kao inhibitori protein kinazeInfo
- Publication number
- YU71703A YU71703A YU71703A YUP71703A YU71703A YU 71703 A YU71703 A YU 71703A YU 71703 A YU71703 A YU 71703A YU P71703 A YUP71703 A YU P71703A YU 71703 A YU71703 A YU 71703A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- protein kinase
- ylmethlidene
- amidopyrrol
- kinase inhibitors
- indolinone derivatives
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Ovaj pronalazak se odnosi na pirol supstituisana 2-indolinon jedinjenja i njihove farmaceutski prihvatljive soli koji moduliraju aktivnost protein kinaza na osnovu čega se očekuje da su korisni u prevenciji i lečenju ćelijskih poremećaja koji su povezani sa protein kinazom kao što je kancer.[The present invention relates to pyrrole substituted 2-indolinone compounds and their pharmaceutically acceptable salts which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related cellular disorders such as cancer.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US26868301P | 2001-02-15 | 2001-02-15 | |
US31236101P | 2001-08-15 | 2001-08-15 |
Publications (2)
Publication Number | Publication Date |
---|---|
YU71703A true YU71703A (sh) | 2006-05-25 |
RS51026B RS51026B (sr) | 2010-10-31 |
Family
ID=26953263
Country Status (41)
Country | Link |
---|---|
US (4) | US6653308B2 (sh) |
EP (1) | EP1370554B1 (sh) |
JP (1) | JP3677501B2 (sh) |
KR (1) | KR100884858B1 (sh) |
CN (1) | CN100338059C (sh) |
AP (1) | AP1718A (sh) |
AR (1) | AR042586A1 (sh) |
AT (1) | ATE307128T1 (sh) |
AU (1) | AU2002247133B2 (sh) |
BG (1) | BG108098A (sh) |
BR (1) | BR0207494A (sh) |
CA (1) | CA2438314C (sh) |
CR (1) | CR7056A (sh) |
CZ (1) | CZ20032414A3 (sh) |
DE (1) | DE60206736T2 (sh) |
DK (1) | DK1370554T3 (sh) |
EA (1) | EA007186B1 (sh) |
EE (1) | EE200300385A (sh) |
ES (1) | ES2251580T3 (sh) |
GE (1) | GEP20053600B (sh) |
HK (1) | HK1059621A1 (sh) |
HR (1) | HRP20030657B1 (sh) |
HU (1) | HUP0303146A3 (sh) |
IL (2) | IL157418A0 (sh) |
IS (1) | IS2411B (sh) |
MA (1) | MA26997A1 (sh) |
MX (1) | MXPA03007367A (sh) |
MY (1) | MY126235A (sh) |
NO (1) | NO326604B1 (sh) |
NZ (1) | NZ527572A (sh) |
OA (1) | OA12834A (sh) |
PE (1) | PE20021006A1 (sh) |
PL (1) | PL364176A1 (sh) |
RS (1) | RS51026B (sh) |
SI (1) | SI1370554T1 (sh) |
SK (1) | SK11332003A3 (sh) |
TN (1) | TNSN03055A1 (sh) |
TW (1) | TWI324155B (sh) |
UA (1) | UA75635C2 (sh) |
WO (1) | WO2002066463A1 (sh) |
ZA (2) | ZA200306335B (sh) |
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