PE120499A1 - Polimorfo antifungico cristalino - Google Patents
Polimorfo antifungico cristalinoInfo
- Publication number
- PE120499A1 PE120499A1 PE1998000942A PE00094298A PE120499A1 PE 120499 A1 PE120499 A1 PE 120499A1 PE 1998000942 A PE1998000942 A PE 1998000942A PE 00094298 A PE00094298 A PE 00094298A PE 120499 A1 PE120499 A1 PE 120499A1
- Authority
- PE
- Peru
- Prior art keywords
- crystalline polymorph
- antifungal
- fenil
- triazol
- hydroxylpropil
- Prior art date
Links
- 230000000843 anti-fungal effect Effects 0.000 title 1
- 229940121375 antifungal agent Drugs 0.000 title 1
- -1 2,4-DIFLUOROPHENYL Chemical class 0.000 abstract 1
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 abstract 1
- 206010017533 Fungal infection Diseases 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 208000031888 Mycoses Diseases 0.000 abstract 1
- 238000002441 X-ray diffraction Methods 0.000 abstract 1
- 238000002329 infrared spectrum Methods 0.000 abstract 1
- 230000000704 physical effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94618397A | 1997-10-07 | 1997-10-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE120499A1 true PE120499A1 (es) | 1999-12-04 |
Family
ID=25484068
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE1998000942A PE120499A1 (es) | 1997-10-07 | 1998-10-05 | Polimorfo antifungico cristalino |
Country Status (30)
| Country | Link |
|---|---|
| EP (1) | EP1021439B1 (enExample) |
| JP (4) | JP2001519346A (enExample) |
| KR (1) | KR100626109B1 (enExample) |
| CN (1) | CN1125067C (enExample) |
| AR (1) | AR015947A1 (enExample) |
| AT (1) | ATE263163T1 (enExample) |
| AU (1) | AU759982B2 (enExample) |
| BR (1) | BR9812866A (enExample) |
| CA (1) | CA2305803C (enExample) |
| CO (1) | CO4970829A1 (enExample) |
| CZ (1) | CZ299835B6 (enExample) |
| DE (1) | DE69822859T2 (enExample) |
| DK (1) | DK1021439T3 (enExample) |
| ES (1) | ES2217594T3 (enExample) |
| HU (1) | HU225233B1 (enExample) |
| ID (1) | ID29290A (enExample) |
| IL (1) | IL135331A (enExample) |
| IN (1) | IN1998CH02232A (enExample) |
| MX (1) | MX225999B (enExample) |
| MY (1) | MY130126A (enExample) |
| NO (1) | NO318827B1 (enExample) |
| NZ (1) | NZ503662A (enExample) |
| PE (1) | PE120499A1 (enExample) |
| PH (1) | PH11998002606B1 (enExample) |
| PL (1) | PL189317B1 (enExample) |
| PT (1) | PT1021439E (enExample) |
| SK (1) | SK285190B6 (enExample) |
| TW (1) | TW589310B (enExample) |
| WO (1) | WO1999018097A1 (enExample) |
| ZA (1) | ZA989063B (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2130540A1 (en) * | 2008-06-02 | 2009-12-09 | Sandoz AG | Pharmaceutical compositions containing a crystalline form of posaconazole |
| EP2141159A1 (en) | 2008-07-03 | 2010-01-06 | Sandoz AG | A Crystalline form of posaconazole |
| CA2767489A1 (en) | 2009-07-09 | 2011-01-13 | Sandoz Ag | A crystalline form of posaconazole |
| US9073904B2 (en) | 2010-05-19 | 2015-07-07 | Sandoz Ag | Preparation of posaconazole intermediates |
| RU2588570C2 (ru) | 2010-05-19 | 2016-07-10 | Сандоз Аг | Способ получения хиральных гидразидов |
| JP6013326B2 (ja) * | 2010-05-19 | 2016-10-25 | サンド・アクチエンゲゼルシヤフト | キラルトリアゾロンの調製のための方法 |
| CA2798010C (en) | 2010-05-19 | 2018-09-25 | Sandoz Ag | Purification of posaconazole and of posaconazole intermediates |
| CN108329303A (zh) | 2011-06-16 | 2018-07-27 | 桑多斯股份公司 | 制备手性化合物的方法 |
| WO2013042138A2 (en) | 2011-09-19 | 2013-03-28 | Msn Laboratories Limited | Process for the preparation of triazole antifungal drug, its intermediates and polymorphs thereof |
| US9670188B2 (en) | 2013-07-25 | 2017-06-06 | Sandoz Ag | Process for the preparation of crystalline form IV of posaconazole |
| ITMI20132117A1 (it) * | 2013-12-18 | 2015-06-19 | Djada Pharmaceutical Sa | Una forma cristallina di posaconazolo |
| ITMI20132114A1 (it) | 2013-12-18 | 2015-06-19 | Djada Pharmaceutical Sa | Una forma cristallina di posaconazolo |
| ITMI20132115A1 (it) * | 2013-12-18 | 2015-06-19 | Djada Pharmaceutical Sa | Una forma cristallina di posaconazolo |
| ITMI20132118A1 (it) * | 2013-12-18 | 2015-06-19 | Djada Pharmaceutical Sa | Una forma cristallina di posaconazolo |
| CN104387374A (zh) * | 2014-10-21 | 2015-03-04 | 江苏恒盛药业有限公司 | 泊沙康唑晶型i的制备工艺 |
| CN104370894A (zh) * | 2014-10-21 | 2015-02-25 | 江苏恒盛药业有限公司 | 无定型泊沙康唑的制备工艺 |
| HRP20201343T1 (hr) | 2014-10-21 | 2020-11-27 | Ariad Pharmaceuticals, Inc. | Kristalni oblici 5-kloro-n4-[-2-(dimetilfosforil)fenil]-n2-{2-metoksi-4-[4-(4-metilpiperazin-1-il)piperidin-1-il]pirimidin-2,4-diamina |
| EP3331501B1 (en) | 2015-08-08 | 2019-09-11 | Alfred E. Tiefenbacher (GmbH & Co. KG) | Gastro-resistant formulation containing posaconazole |
| EP3394045B1 (en) | 2015-12-24 | 2021-05-19 | Takeda Pharmaceutical Company Limited | Cocrystal, production method thereof, and medicament containing cocrystal |
| EP3925601B1 (en) | 2016-02-26 | 2024-07-17 | Alfred E. Tiefenbacher (GmbH & Co. KG) | Gastro-resistant formulation containing posaconazole and a polymeric precipitation inhibitor |
| CN105949278B (zh) * | 2016-03-30 | 2019-12-06 | 南京曼杰生物科技有限公司 | 一种取代的四氢呋喃水溶性衍生物及其应用 |
| WO2017032908A1 (en) | 2016-07-08 | 2017-03-02 | Synthon B.V. | Pharmaceutical composition comprising amorphous posaconazole |
| TR201620462A2 (tr) | 2016-12-31 | 2018-07-23 | Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi | POSAKONAZOL İÇEREN FARMASÖTİK BİLEŞİMLER ve ÜRETİM YÖNTEMİ |
| TR201722493A2 (tr) | 2017-12-28 | 2019-07-22 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Posakonazol i̇çeren kati farmasöti̇k kompozi̇syon |
| EP4196096A1 (en) | 2020-08-13 | 2023-06-21 | Alfred E. Tiefenbacher (GmbH & Co. KG) | Gastro-resistant high-strength formulation containing posaconazole |
| EP4091604B1 (en) | 2021-11-25 | 2024-04-03 | Alfred E. Tiefenbacher (GmbH & Co. KG) | Granules containing posaconazole |
| EP4181883B1 (en) | 2021-11-25 | 2025-11-19 | Alfred E. Tiefenbacher (GmbH & Co. KG) | Granules containing posaconazole |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL103558A0 (en) * | 1991-10-30 | 1993-03-15 | Schering Corp | Tri-substituted tetrahydrofuran antifungals |
| PL181193B1 (pl) * | 1993-12-21 | 2001-06-29 | Schering Corp | Nowe pochodne tetrahydrofuranowe o działaniu przeciwgrzybicznym, kompozycja farmaceutyczna do leczenia infekcji grzybiczych oraz sposób wytwarzania tych związków |
| KR100352147B1 (ko) * | 1994-01-24 | 2002-11-11 | 얀센 파마슈티카 엔.브이. | 수용성아졸항진균제 |
| US5625064A (en) * | 1995-04-19 | 1997-04-29 | Schering Corporation | Process for the preparation of triazolones |
| WO1996038443A1 (en) * | 1995-06-02 | 1996-12-05 | Schering Corporation | Tetrahydrofuran antifungals |
-
1998
- 1998-10-05 AR ARP980104957A patent/AR015947A1/es not_active Application Discontinuation
- 1998-10-05 HU HU0004899A patent/HU225233B1/hu unknown
- 1998-10-05 CN CN98811886A patent/CN1125067C/zh not_active Expired - Lifetime
- 1998-10-05 DE DE69822859T patent/DE69822859T2/de not_active Expired - Lifetime
- 1998-10-05 DK DK98951994T patent/DK1021439T3/da active
- 1998-10-05 ES ES98951994T patent/ES2217594T3/es not_active Expired - Lifetime
- 1998-10-05 BR BR9812866-3A patent/BR9812866A/pt not_active Application Discontinuation
- 1998-10-05 AT AT98951994T patent/ATE263163T1/de active
- 1998-10-05 ZA ZA989063A patent/ZA989063B/xx unknown
- 1998-10-05 PT PT98951994T patent/PT1021439E/pt unknown
- 1998-10-05 ID IDW20000632A patent/ID29290A/id unknown
- 1998-10-05 IL IL13533198A patent/IL135331A/xx not_active IP Right Cessation
- 1998-10-05 CZ CZ20001264A patent/CZ299835B6/cs not_active IP Right Cessation
- 1998-10-05 NZ NZ503662A patent/NZ503662A/xx not_active IP Right Cessation
- 1998-10-05 PL PL98339659A patent/PL189317B1/pl unknown
- 1998-10-05 KR KR20007003709A patent/KR100626109B1/ko not_active Expired - Lifetime
- 1998-10-05 SK SK512-2000A patent/SK285190B6/sk not_active IP Right Cessation
- 1998-10-05 EP EP98951994A patent/EP1021439B1/en not_active Expired - Lifetime
- 1998-10-05 AU AU97803/98A patent/AU759982B2/en not_active Expired
- 1998-10-05 CA CA002305803A patent/CA2305803C/en not_active Expired - Lifetime
- 1998-10-05 CO CO98057733A patent/CO4970829A1/es unknown
- 1998-10-05 JP JP2000514908A patent/JP2001519346A/ja not_active Withdrawn
- 1998-10-05 WO PCT/US1998/020476 patent/WO1999018097A1/en not_active Ceased
- 1998-10-05 PE PE1998000942A patent/PE120499A1/es not_active IP Right Cessation
- 1998-10-06 PH PH11998002606A patent/PH11998002606B1/en unknown
- 1998-10-06 TW TW087116562A patent/TW589310B/zh not_active IP Right Cessation
- 1998-10-06 MY MYPI98004576A patent/MY130126A/en unknown
- 1998-10-06 IN IN2232CH1998 patent/IN1998CH02232A/en unknown
-
2000
- 2000-04-06 MX MXPA00003404 patent/MX225999B/es active IP Right Grant
- 2000-04-06 NO NO20001779A patent/NO318827B1/no not_active IP Right Cessation
-
2008
- 2008-01-04 JP JP2008000110A patent/JP2008106075A/ja not_active Withdrawn
-
2012
- 2012-05-18 JP JP2012114725A patent/JP2012153730A/ja active Pending
- 2012-05-18 JP JP2012114724A patent/JP2012153729A/ja active Pending
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration | ||
| MK | Expiration of term |