PE120499A1 - Polimorfo antifungico cristalino - Google Patents
Polimorfo antifungico cristalinoInfo
- Publication number
- PE120499A1 PE120499A1 PE1998000942A PE00094298A PE120499A1 PE 120499 A1 PE120499 A1 PE 120499A1 PE 1998000942 A PE1998000942 A PE 1998000942A PE 00094298 A PE00094298 A PE 00094298A PE 120499 A1 PE120499 A1 PE 120499A1
- Authority
- PE
- Peru
- Prior art keywords
- crystalline polymorph
- antifungal
- fenil
- triazol
- hydroxylpropil
- Prior art date
Links
- 230000000843 anti-fungal effect Effects 0.000 title 1
- 229940121375 antifungal agent Drugs 0.000 title 1
- -1 2,4-DIFLUOROPHENYL Chemical class 0.000 abstract 1
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 abstract 1
- 206010017533 Fungal infection Diseases 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 208000031888 Mycoses Diseases 0.000 abstract 1
- 238000002441 X-ray diffraction Methods 0.000 abstract 1
- 238000002329 infrared spectrum Methods 0.000 abstract 1
- 230000000704 physical effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94618397A | 1997-10-07 | 1997-10-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE120499A1 true PE120499A1 (es) | 1999-12-04 |
Family
ID=25484068
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE1998000942A PE120499A1 (es) | 1997-10-07 | 1998-10-05 | Polimorfo antifungico cristalino |
Country Status (30)
| Country | Link |
|---|---|
| EP (1) | EP1021439B1 (enExample) |
| JP (4) | JP2001519346A (enExample) |
| KR (1) | KR100626109B1 (enExample) |
| CN (1) | CN1125067C (enExample) |
| AR (1) | AR015947A1 (enExample) |
| AT (1) | ATE263163T1 (enExample) |
| AU (1) | AU759982B2 (enExample) |
| BR (1) | BR9812866A (enExample) |
| CA (1) | CA2305803C (enExample) |
| CO (1) | CO4970829A1 (enExample) |
| CZ (1) | CZ299835B6 (enExample) |
| DE (1) | DE69822859T2 (enExample) |
| DK (1) | DK1021439T3 (enExample) |
| ES (1) | ES2217594T3 (enExample) |
| HU (1) | HU225233B1 (enExample) |
| ID (1) | ID29290A (enExample) |
| IL (1) | IL135331A (enExample) |
| IN (1) | IN1998CH02232A (enExample) |
| MX (1) | MX225999B (enExample) |
| MY (1) | MY130126A (enExample) |
| NO (1) | NO318827B1 (enExample) |
| NZ (1) | NZ503662A (enExample) |
| PE (1) | PE120499A1 (enExample) |
| PH (1) | PH11998002606B1 (enExample) |
| PL (1) | PL189317B1 (enExample) |
| PT (1) | PT1021439E (enExample) |
| SK (1) | SK285190B6 (enExample) |
| TW (1) | TW589310B (enExample) |
| WO (1) | WO1999018097A1 (enExample) |
| ZA (1) | ZA989063B (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2130540A1 (en) * | 2008-06-02 | 2009-12-09 | Sandoz AG | Pharmaceutical compositions containing a crystalline form of posaconazole |
| EP2141159A1 (en) * | 2008-07-03 | 2010-01-06 | Sandoz AG | A Crystalline form of posaconazole |
| CA2767489A1 (en) | 2009-07-09 | 2011-01-13 | Sandoz Ag | A crystalline form of posaconazole |
| EP2571847B1 (en) | 2010-05-19 | 2016-09-21 | Sandoz AG | Process for the preparation of chiral hydrazides |
| US9073904B2 (en) | 2010-05-19 | 2015-07-07 | Sandoz Ag | Preparation of posaconazole intermediates |
| CN102892763B (zh) | 2010-05-19 | 2016-03-09 | 桑多斯股份公司 | 泊沙康唑及泊沙康唑中间体的纯化 |
| AU2011254654B2 (en) * | 2010-05-19 | 2016-01-07 | Sandoz Ag | Process for the preparation of chiral triazolones |
| CN103635465A (zh) | 2011-06-16 | 2014-03-12 | 桑多斯股份公司 | 制备手性化合物的方法 |
| EP2758385B1 (en) * | 2011-09-19 | 2018-03-28 | MSN Laboratories Limited | Process for the preparation of triazole antifungal drug, its intermediates and polymorphs thereof |
| WO2015011224A1 (en) | 2013-07-25 | 2015-01-29 | Sandoz Ag | Improved process for the preparation of crystalline form iv of posaconazole |
| ITMI20132114A1 (it) * | 2013-12-18 | 2015-06-19 | Djada Pharmaceutical Sa | Una forma cristallina di posaconazolo |
| ITMI20132117A1 (it) * | 2013-12-18 | 2015-06-19 | Djada Pharmaceutical Sa | Una forma cristallina di posaconazolo |
| ITMI20132115A1 (it) * | 2013-12-18 | 2015-06-19 | Djada Pharmaceutical Sa | Una forma cristallina di posaconazolo |
| ITMI20132118A1 (it) * | 2013-12-18 | 2015-06-19 | Djada Pharmaceutical Sa | Una forma cristallina di posaconazolo |
| CN104387374A (zh) * | 2014-10-21 | 2015-03-04 | 江苏恒盛药业有限公司 | 泊沙康唑晶型i的制备工艺 |
| CN104370894A (zh) * | 2014-10-21 | 2015-02-25 | 江苏恒盛药业有限公司 | 无定型泊沙康唑的制备工艺 |
| PT3209647T (pt) | 2014-10-21 | 2020-09-10 | Ariad Pharma Inc | Formas cristalinas de 5-cloro-n4-[2-(dimetilfosforil)fenil]-n2-{2-metoxi-4-[4-(4-metilpiperazin-1-il)piperidin-1-il]pirimidino-2,4-diamina |
| US11058682B2 (en) | 2015-08-08 | 2021-07-13 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Gastro-resistant formulation containing posaconazole |
| WO2017111179A1 (en) | 2015-12-24 | 2017-06-29 | Takeda Pharmaceutical Company Limited | Cocrystal, production method thereof, and medicament containing cocrystal |
| EP3925601B1 (en) | 2016-02-26 | 2024-07-17 | Alfred E. Tiefenbacher (GmbH & Co. KG) | Gastro-resistant formulation containing posaconazole and a polymeric precipitation inhibitor |
| CN105949278B (zh) * | 2016-03-30 | 2019-12-06 | 南京曼杰生物科技有限公司 | 一种取代的四氢呋喃水溶性衍生物及其应用 |
| WO2017032908A1 (en) | 2016-07-08 | 2017-03-02 | Synthon B.V. | Pharmaceutical composition comprising amorphous posaconazole |
| TR201620462A2 (tr) | 2016-12-31 | 2018-07-23 | Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi | POSAKONAZOL İÇEREN FARMASÖTİK BİLEŞİMLER ve ÜRETİM YÖNTEMİ |
| TR201722493A2 (tr) | 2017-12-28 | 2019-07-22 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Posakonazol i̇çeren kati farmasöti̇k kompozi̇syon |
| EP4196096A1 (en) | 2020-08-13 | 2023-06-21 | Alfred E. Tiefenbacher (GmbH & Co. KG) | Gastro-resistant high-strength formulation containing posaconazole |
| EP4091604B1 (en) | 2021-11-25 | 2024-04-03 | Alfred E. Tiefenbacher (GmbH & Co. KG) | Granules containing posaconazole |
| WO2023012378A1 (en) | 2021-11-25 | 2023-02-09 | Alfred E. Tiefenbacher (Gmbh Und Co. Kg) | Granules containing posaconazole |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL103558A0 (en) * | 1991-10-30 | 1993-03-15 | Schering Corp | Tri-substituted tetrahydrofuran antifungals |
| DK0736030T3 (da) * | 1993-12-21 | 2001-10-29 | Schering Corp | Fungicide tetrahydrofuraner |
| SG48386A1 (en) * | 1994-01-24 | 1998-04-17 | Janssen Pharmaceutica Nv | Watersoluble azole antifungals |
| US5625064A (en) * | 1995-04-19 | 1997-04-29 | Schering Corporation | Process for the preparation of triazolones |
| ES2199291T3 (es) * | 1995-06-02 | 2004-02-16 | Schering Corporation | Antifungicos de tetrahidrofurano. |
-
1998
- 1998-10-05 JP JP2000514908A patent/JP2001519346A/ja not_active Withdrawn
- 1998-10-05 CZ CZ20001264A patent/CZ299835B6/cs not_active IP Right Cessation
- 1998-10-05 PT PT98951994T patent/PT1021439E/pt unknown
- 1998-10-05 CO CO98057733A patent/CO4970829A1/es unknown
- 1998-10-05 IL IL13533198A patent/IL135331A/xx not_active IP Right Cessation
- 1998-10-05 ID IDW20000632A patent/ID29290A/id unknown
- 1998-10-05 ES ES98951994T patent/ES2217594T3/es not_active Expired - Lifetime
- 1998-10-05 HU HU0004899A patent/HU225233B1/hu unknown
- 1998-10-05 WO PCT/US1998/020476 patent/WO1999018097A1/en not_active Ceased
- 1998-10-05 PE PE1998000942A patent/PE120499A1/es not_active IP Right Cessation
- 1998-10-05 AT AT98951994T patent/ATE263163T1/de active
- 1998-10-05 SK SK512-2000A patent/SK285190B6/sk not_active IP Right Cessation
- 1998-10-05 KR KR20007003709A patent/KR100626109B1/ko not_active Expired - Lifetime
- 1998-10-05 EP EP98951994A patent/EP1021439B1/en not_active Expired - Lifetime
- 1998-10-05 CA CA002305803A patent/CA2305803C/en not_active Expired - Lifetime
- 1998-10-05 NZ NZ503662A patent/NZ503662A/xx not_active IP Right Cessation
- 1998-10-05 PL PL98339659A patent/PL189317B1/pl unknown
- 1998-10-05 ZA ZA989063A patent/ZA989063B/xx unknown
- 1998-10-05 DK DK98951994T patent/DK1021439T3/da active
- 1998-10-05 BR BR9812866-3A patent/BR9812866A/pt not_active Application Discontinuation
- 1998-10-05 AU AU97803/98A patent/AU759982B2/en not_active Expired
- 1998-10-05 CN CN98811886A patent/CN1125067C/zh not_active Expired - Lifetime
- 1998-10-05 AR ARP980104957A patent/AR015947A1/es not_active Application Discontinuation
- 1998-10-05 DE DE69822859T patent/DE69822859T2/de not_active Expired - Lifetime
- 1998-10-06 IN IN2232CH1998 patent/IN1998CH02232A/en unknown
- 1998-10-06 TW TW087116562A patent/TW589310B/zh not_active IP Right Cessation
- 1998-10-06 MY MYPI98004576A patent/MY130126A/en unknown
- 1998-10-06 PH PH11998002606A patent/PH11998002606B1/en unknown
-
2000
- 2000-04-06 NO NO20001779A patent/NO318827B1/no not_active IP Right Cessation
- 2000-04-06 MX MXPA00003404 patent/MX225999B/es active IP Right Grant
-
2008
- 2008-01-04 JP JP2008000110A patent/JP2008106075A/ja not_active Withdrawn
-
2012
- 2012-05-18 JP JP2012114724A patent/JP2012153729A/ja active Pending
- 2012-05-18 JP JP2012114725A patent/JP2012153730A/ja active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CO4970829A1 (es) | Polimorfo antifungico cristalino | |
| BR9910621A (pt) | Novos compostos de imidazol 2-alquil substituìdos | |
| NO924522L (no) | Optisk aktive azolforbindelser, deres fremstilling og anvendelse | |
| TR200000333T2 (tr) | Y alıcı antagonistleri olarak 4-aminopirol (3,2-d) pirimidinler. | |
| BR0010020A (pt) | Material não tramado com alto relevo e método de fabricação do mesmo | |
| PE20091618A1 (es) | 1,2,4-triazoles trisustituidos | |
| PT939627E (pt) | Pentafluorobenzenossulfonamidas e analogos | |
| BR0313763A (pt) | Imidazóis 2,4,5-trissubstituìdos e seu uso como agentes antimicrobianos | |
| UY26253A1 (es) | Derivados del triazol y del imidazol | |
| DE69105061D1 (de) | Verfahren zur fungiziden Blattbehandlung mit einem Triazol und fungizide Zusammensetzung zur Durchführung dieses Verfahrens. | |
| DE2967005D1 (en) | 2-alkoxycarbonylamino benzimidazoles having a halogen-containing substituent, their preparation and their use as parasiticides | |
| ES2150445T3 (es) | Medicamento anti-isquemico. | |
| BR0108990A (pt) | Processo para preparação de derivados de pirimidona com atividade antifungos | |
| BG105840A (en) | Heterocyclic benzenesulphonamide compounds as bradykinine antagonists | |
| DK0559867T3 (da) | Anvendelse af phosphoniumforbindelser ved fremstilling af læder | |
| CY1111510T1 (el) | Ενδιαμεσα παραγωγα αλογονοφaiνυλiου και η χρηση αυτων σε μια μεθοδο για την παρασκευη παραγωγων αζολης | |
| CO4840511A1 (es) | Composicion antifungica que contiene (2r-cis)-4-[4-[4-[4- [[-5-(2,4-difluorofenil)tetrahidro-5-(1h-1,2,4-triazol-1- ilmetil)furan-3-il]metoxi]fenil]-1-piperazinil]fenil]2-4- dihidro-2-[(s)-1-etil-2(s)-hidroxipropil-3h-1,2,4- triazol-3-ona | |
| WO2003086271A3 (en) | Azole derivatives as antifungal agents | |
| ES2176758T3 (es) | Procedimiento para la preparacion de 4-ciona-1,2,3-triazxoles. | |
| BRPI9909471B8 (pt) | processo para a produção de 5,6-dicloro-2-(isopropilamino)-1-beta-l-ribofuranosil-1h-benzimidazol na forma vi cristalina anidra | |
| ES8503680A1 (es) | Un procedimiento para la preparacion de un compuesto dotado de propiedades fungicidas | |
| ECSP982686A (es) | Poliformo antifungico cristalino | |
| BR0002514A (pt) | Derivados de 4-arilpiperidina para o tratamento de prurido | |
| ATE38516T1 (de) | 4(5)-substituierte imidazole. | |
| YU3701A (sh) | Supstituisani fenilamidini sa antitrombskim dejstvom |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration | ||
| MK | Expiration of term |