NO924522L - Optisk aktive azolforbindelser, deres fremstilling og anvendelse - Google Patents

Optisk aktive azolforbindelser, deres fremstilling og anvendelse

Info

Publication number
NO924522L
NO924522L NO92924522A NO924522A NO924522L NO 924522 L NO924522 L NO 924522L NO 92924522 A NO92924522 A NO 92924522A NO 924522 A NO924522 A NO 924522A NO 924522 L NO924522 L NO 924522L
Authority
NO
Norway
Prior art keywords
group
nitrogen
heterocyclic group
substituted
atoms
Prior art date
Application number
NO92924522A
Other languages
English (en)
Other versions
NO924522D0 (no
Inventor
Katsumi Itoh
Kenji Okonogi
Norikazu Tamura
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of NO924522D0 publication Critical patent/NO924522D0/no
Publication of NO924522L publication Critical patent/NO924522L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Det er beskrevet en optisk aktiv azolforbindelse med formel (I): hvor R1 og R2 uavhengig av hverandre er et hydrogen- atom, et halogenatom, en halogenalkylgruppe, en halogenalkoksygruppe eller en eventuelt substituert, nitrogenholdlg, heterocyklisk gruppe; R3 er et hydrogenatom eller en acylgruppe; O er CH eller N: -NÅ} er en nitrogenholdig, aromatisk, femleddet heterocyklisk gruppe som har minst to nabostllte nltrogenatomer som ringoppbyggende atomer som kan være substituerte, eller en aromatisk, kondensert, hetero- cyklisk gruppe Inneholdende to eller flere nitrogen- atomer som ringoppbyggende atomer som kan være substituerte; og (R) viser at karbonatomet merket med j (R) har R-konfigurasjon; forutsatt at en av R1 og R2 er i en eventuelt substituert, nitrogenholdlg, heterocyklisk j gruppe når -NÅ) er en 1H-1,2,4-trlazol-l-yl-gruppe, eller et salt derav. Forbindelsen er nyttig som anti- soppmlddel. Det er videre angitt en fremgangsmåte for fremstilling av forbindelsene.
NO92924522A 1991-11-25 1992-11-24 Optisk aktive azolforbindelser, deres fremstilling og anvendelse NO924522L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP30906991 1991-11-25
JP1988892 1992-02-05
JP14551092 1992-06-05

Publications (2)

Publication Number Publication Date
NO924522D0 NO924522D0 (no) 1992-11-24
NO924522L true NO924522L (no) 1993-05-26

Family

ID=27282810

Family Applications (1)

Application Number Title Priority Date Filing Date
NO92924522A NO924522L (no) 1991-11-25 1992-11-24 Optisk aktive azolforbindelser, deres fremstilling og anvendelse

Country Status (10)

Country Link
US (2) US5371100A (no)
EP (1) EP0548553A1 (no)
CN (2) CN1072680A (no)
AU (1) AU653082B2 (no)
CA (1) CA2083679A1 (no)
FI (1) FI925323A (no)
HU (1) HUT62574A (no)
NO (1) NO924522L (no)
NZ (1) NZ245226A (no)
TW (1) TW212798B (no)

Families Citing this family (34)

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ES2099004B1 (es) * 1993-02-11 1998-01-16 Uriach & Cia Sa J Nuevos antifungicos activos por via oral.
ES2062941B1 (es) * 1993-03-15 1995-10-01 Uriach & Cia Sa J Nuevos derivados de azol activos por via oral.
HU212458B (en) * 1993-09-23 1996-06-28 Richter Gedeon Vegyeszet New silyloxypropane derivatives substituted with triazole or imidazole pharmaceutical compositions containing them and process for producing them
TW297813B (no) * 1993-09-24 1997-02-11 Takeda Pharm Industry Co Ltd
CA2134417A1 (en) * 1993-12-22 1995-06-23 Katsumi Itoh Optically active azole derivatives, their production and use
NZ270418A (en) * 1994-02-07 1997-09-22 Eisai Co Ltd Polycyclic triazole & imidazole derivatives, antifungal compositions
US5677464A (en) * 1994-05-31 1997-10-14 Takeda Chemical Industries, Ltd. Production of optically active triazole compounds and their intermediates
TW318841B (no) * 1995-02-17 1997-11-01 Takeda Pharm Industry Co Ltd
AU4675596A (en) * 1995-02-17 1996-09-04 Takeda Chemical Industries Ltd. Azole compounds, their production and use
JP2001507359A (ja) * 1997-01-03 2001-06-05 エラン コーポレーション ピーエルシー 徐放性シサプリドミニ錠剤製剤
US6432947B1 (en) * 1997-02-19 2002-08-13 Berlex Laboratories, Inc. N-heterocyclic derivatives as NOS inhibitors
WO1998043970A1 (en) 1997-03-31 1998-10-08 Takeda Chemical Industries, Ltd. Azole compounds, their production and their use
US6133485A (en) * 1998-04-15 2000-10-17 Synphar Laboratories, Inc. Asymmetric synthesis of 2-(2,4-difluorophenyl)-1-heterocycl-1-yl butan-2,3-diols
WO2000018401A1 (fr) 1998-09-29 2000-04-06 Takeda Chemical Industries, Ltd. Composition de medicament antimycotique
IN192526B (no) * 2001-09-25 2004-04-24 Ranbaxy Lab
US7028055B2 (en) * 2002-03-22 2006-04-11 Sun Microsystems, Inc. Method and apparatus for improving transaction specification by marking application states
KR100572996B1 (ko) * 2003-08-12 2006-04-25 한국화학연구원 불소화 비닐 에테르 측쇄기를 갖는 아졸계 살균제 화합물및 그의 제조방법
KR101048535B1 (ko) * 2005-03-30 2011-07-11 주식회사 대웅제약 항진균성 트리아졸 유도체
KR100998816B1 (ko) * 2005-10-31 2010-12-06 주식회사 대웅제약 신규한 항진균성 트리아졸 유도체
US8680270B2 (en) 2006-11-21 2014-03-25 Viamet Pharmaceuticals, Inc. Metallo-oxidoreductase inhibitors using metal binding moieties in combination with targeting moieties
KR20080062876A (ko) * 2006-12-29 2008-07-03 주식회사 대웅제약 신규한 항진균성 트리아졸 유도체
CA2799154A1 (en) 2010-05-12 2011-11-17 Abbvie Inc. Indazole inhibitors of kinase
KR101964195B1 (ko) 2011-06-23 2019-04-01 비아멧 파마슈티컬즈(엔씨), 인코포레이티드 금속효소 억제제 화합물
TWI646088B (zh) * 2012-03-16 2019-01-01 維愛美製藥公司 金屬酶抑制劑化合物
US8889730B2 (en) 2012-04-10 2014-11-18 Pfizer Inc. Indole and indazole compounds that activate AMPK
EP2746262A1 (en) * 2012-12-19 2014-06-25 Basf Se Substituted [1,2,4]triazole and imidazole compounds for combating phytopathogenic fungi
EP2961743B1 (en) 2013-03-01 2018-06-20 FDC Limited 1-substituted, 4-(substituted phenoxymethyl)-1,2,3-triazole compounds with antifungal properties and methods for preparation thereof
EP2968284B1 (en) 2013-03-14 2021-04-21 Osteoqc Inc. Alkyl-amine harmine derivatives for promoting bone growth
CA2905242C (en) 2013-03-15 2016-11-29 Pfizer Inc. Indole compounds that activate ampk
WO2017020944A1 (en) 2015-07-31 2017-02-09 Universite De Nantes Novel fused pyrimidinone and triazinone derivatives, their process of preparation and their therapeutic uses as antifungal and/or antiparasitic agents
CN106518922A (zh) * 2015-09-12 2017-03-22 陕西合成药业股份有限公司 一种三唑类化合物及其制备方法和用途
JP2022504011A (ja) 2018-08-14 2022-01-13 オステオーク インコーポレイティド ピロロ－ジピリジン化合物
WO2020037001A1 (en) 2018-08-14 2020-02-20 Osteoqc Inc. FLUORO β-CARBOLINE COMPOUNDS
CN111217795B (zh) * 2020-02-14 2023-07-18 华侨大学 一种抗菌药物及其制备方法

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Publication number Priority date Publication date Assignee Title
GB2078719B (en) * 1980-06-02 1984-04-26 Ici Ltd Heterocyclic compounds
EP0069442B1 (en) * 1981-06-06 1985-02-20 Pfizer Limited Antifungal agents, processes for their preparation, and pharmaceutical compositions containing them
DE3307218A1 (de) * 1983-03-02 1984-09-06 Bayer Ag, 5090 Leverkusen Substituierte diazolylalkyl-carbinole, verfahren zu ihrer herstellung und ihre verwendung als antimykotische mittel
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DK159205C (da) * 1983-03-16 1991-03-04 Pfizer Bis(triazol)alkanol-forbindelser, anvendelse af disse, farmaceutiske praeparater og landbrugsfungicider indeholdende disse og fremgangsmaade til behandling af planter eller froe, som har en svampeinfektion
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IE903395A1 (en) * 1989-09-26 1991-04-10 Takeda Chemical Industries Ltd Triazole compounds, their production and use

Also Published As

Publication number Publication date
FI925323A0 (fi) 1992-11-24
NO924522D0 (no) 1992-11-24
TW212798B (no) 1993-09-11
AU653082B2 (en) 1994-09-15
US5495024A (en) 1996-02-27
NZ245226A (en) 1994-10-26
AU2859292A (en) 1994-03-31
HU9203661D0 (en) 1993-03-01
CN1072680A (zh) 1993-06-02
FI925323A (fi) 1993-05-26
CA2083679A1 (en) 1993-05-26
CN1075143A (zh) 1993-08-11
EP0548553A1 (en) 1993-06-30
HUT62574A (en) 1993-05-28
US5371100A (en) 1994-12-06

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