ES2099004B1 - Nuevos antifungicos activos por via oral. - Google Patents

Nuevos antifungicos activos por via oral.

Info

Publication number
ES2099004B1
ES2099004B1 ES09300268A ES9300268A ES2099004B1 ES 2099004 B1 ES2099004 B1 ES 2099004B1 ES 09300268 A ES09300268 A ES 09300268A ES 9300268 A ES9300268 A ES 9300268A ES 2099004 B1 ES2099004 B1 ES 2099004B1
Authority
ES
Spain
Prior art keywords
oral route
new anti
fungi active
compounds
fungi
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES09300268A
Other languages
English (en)
Other versions
ES2099004A1 (es
Inventor
Javier Bartroli
Enric Turmo
Elena Carceller
Carmen Almansa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Noucor Health SA
Original Assignee
J Uriach y Cia SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by J Uriach y Cia SA filed Critical J Uriach y Cia SA
Priority to ES09300268A priority Critical patent/ES2099004B1/es
Priority to CA002113972A priority patent/CA2113972A1/en
Priority to KR1019940002474A priority patent/KR940019692A/ko
Priority to EP94102139A priority patent/EP0612734A1/en
Priority to JP6039178A priority patent/JPH06271551A/ja
Publication of ES2099004A1 publication Critical patent/ES2099004A1/es
Application granted granted Critical
Publication of ES2099004B1 publication Critical patent/ES2099004B1/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A01N43/647—Triazoles; Hydrogenated triazoles
    • A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pest Control & Pesticides (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

COMPUESTOS DE FORMULA I, EN FORMA DE RACEMICOS O EN FORMA DE SU ENANTIOMEROS BIOLOGICAMENTE ACTIVOS PUROS (R,R), Y SUS SALES Y SOLVATOS, EN DONDE R1 ES H O FORMA UN ANILLO DE OXAZOLIDINA CON R2; R2 ES H, C1-C4 ALQUILO O FORMA UN ANILLO DE OXAZOLIDINA JUNTO CON R1; Y P ES 0 O 1. DICHOS COMPUESTOS SON UTILES COMO ANTIFUNGICOS. LA PRESENTE INVENCION DESCRIBE TAMBIEN PROCEDIMIENTOS PARA SU OBTENCION Y COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN.
ES09300268A 1993-02-11 1993-02-11 Nuevos antifungicos activos por via oral. Expired - Lifetime ES2099004B1 (es)

Priority Applications (5)

Application Number Priority Date Filing Date Title
ES09300268A ES2099004B1 (es) 1993-02-11 1993-02-11 Nuevos antifungicos activos por via oral.
CA002113972A CA2113972A1 (en) 1993-02-11 1994-01-21 Orally active antifungal agents
KR1019940002474A KR940019692A (ko) 1993-02-11 1994-02-08 신규의 경구 활성 항진균제
EP94102139A EP0612734A1 (en) 1993-02-11 1994-02-11 Novel orally active antifungal agents
JP6039178A JPH06271551A (ja) 1993-02-11 1994-02-14 経口的に活性な新規抗真菌剤

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES09300268A ES2099004B1 (es) 1993-02-11 1993-02-11 Nuevos antifungicos activos por via oral.

Publications (2)

Publication Number Publication Date
ES2099004A1 ES2099004A1 (es) 1997-05-01
ES2099004B1 true ES2099004B1 (es) 1998-01-16

Family

ID=8280763

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09300268A Expired - Lifetime ES2099004B1 (es) 1993-02-11 1993-02-11 Nuevos antifungicos activos por via oral.

Country Status (5)

Country Link
EP (1) EP0612734A1 (es)
JP (1) JPH06271551A (es)
KR (1) KR940019692A (es)
CA (1) CA2113972A1 (es)
ES (1) ES2099004B1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6133485A (en) * 1998-04-15 2000-10-17 Synphar Laboratories, Inc. Asymmetric synthesis of 2-(2,4-difluorophenyl)-1-heterocycl-1-yl butan-2,3-diols

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8332788D0 (en) * 1983-12-08 1984-01-18 Ici Plc Antifungal triazole compound
NO171272C (no) * 1988-03-04 1993-02-17 Sankyo Co Analogifremgangsmaate til fremstilling av terapeutisk aktive 1,2,4-triazolforbindelser
CA2031892C (en) * 1989-12-25 2000-08-01 Minoru Tokizawa Triazole derivatives
ES2024332A6 (es) * 1990-10-08 1992-02-16 Uriach & Cia Sa J Procedimiento para la obtencion de nuevas sulfonamidas.
EP0548553A1 (en) * 1991-11-25 1993-06-30 Takeda Chemical Industries, Ltd. Optically active azole compounds, their production and use

Also Published As

Publication number Publication date
CA2113972A1 (en) 1994-08-12
EP0612734A1 (en) 1994-08-31
KR940019692A (ko) 1994-09-14
ES2099004A1 (es) 1997-05-01
JPH06271551A (ja) 1994-09-27

Similar Documents

Publication Publication Date Title
ES2188957T3 (es) N-(4-(heteroarilmetil)fenil)-heteroarilaminas.
AR055878A1 (es) Derivados de ciclopropanocarboxamida
ECSP045229A (es) Piridinonas sustituidas como moduladores de la p38 map quinasa
UY26727A1 (es) Derivados de tropano útiles en terapia
AR009413A1 (es) Un compuesto, el cual es un derivado de distamicina benzoheterociclico, su utilizacion, un procedimiento para producirlo y una composicionfarmaceutica que lo comprende
HUP0402566A2 (hu) C-5 módosított indazolilamino-pirrolotriazinok, alkalmazásuk és az ezeket tartalmazó gyógyszerkészítmények
CO4920223A1 (es) Derivados de 1,3,8-triaza-espiro[4,5]decan-4-ona 8- sustituidos
ES8400415A1 (es) "un procedimiento para la preparacion de derivados de 2,4-diaminoquinazolina".
MX9207074A (es) Piperazinil- y piperidinil -ciclohexanoles y composicion farmaceutica que los comprende
PA8442101A1 (es) Pirazoles parasiticidas
HUP0100638A2 (hu) FP agonistákként alkalmazható aromás C16-C20-szubsztituált tetrahidroprosztaglandinok és ezeket tartalmazó gyógyszerkészítmények
MX9302948A (es) Imidazolinonas fungicidas y composicion fungicida que las contiene.
CO5550439A2 (es) Compuestos derivados de arilsulfonil-piperazina que tienen afinidad al receptor 5-ht6 y composiciones farmaceuticas que los contienen
AR007108A1 (es) Agentes antitumorales y antivirales alquilantes, procedimiento para su preparacion, utilizacion de los mismos para la fabricacion de un medicamento y composicion farmaceutica que contiene a dichos agentes.
FI851996L (fi) Nya substituerade bis-(4-aminofenyl) -sulfoner, deras framstaellning och deras anvaendning saosom laekemedel.
AR040140A1 (es) Derivados de esteres de camptotecina en la posicion 20
AR054414A1 (es) Compuestos espiro-hidantoina sustituidos con piridilo. composiciones farmaceuticas.
MX9307271A (es) Derivados de 2-alcoxi-2 imidazolin-5-onas, procedimiento para su preparacion y composicion fungicida que los contiene.
ES2099004B1 (es) Nuevos antifungicos activos por via oral.
MX9306394A (es) Derivados de benzofurano, proceso para su preparacion y composicion farmaceutica que los contiene
AR040139A1 (es) Camptotecinas con un anillo lactona modificado
AR035765A1 (es) Composiciones fungicidas de n-2-piridinilmetilbenzamida y del propil ester de acido (3-(dimetilamino)-propil) carbamico; procedimientos curativos o preventivos contra hongos fitopatogenos de cultivos, utilizando dichas composiciones y productos de aplicacion combinada, simultanea, separada o secuenc
DK266686A (da) 1-aryl-5-alkoximinoalkylaminopyrazoler, fremgangsmaader til fremstilling deraf og deres anvendelse som herbicider og vaekstregulatorer
AR009452A1 (es) Compuestos de dihalopropeno, los agentes insecticidas/acaricidas que los contienen y los intermediarios de sintesis de dichos compuestos.
MX9101948A (es) Composicion farmaceutica que contiene derivados de tiazoloisoindolinona