ES2176758T3 - Procedimiento para la preparacion de 4-ciona-1,2,3-triazxoles. - Google Patents

Procedimiento para la preparacion de 4-ciona-1,2,3-triazxoles.

Info

Publication number
ES2176758T3
ES2176758T3 ES97932803T ES97932803T ES2176758T3 ES 2176758 T3 ES2176758 T3 ES 2176758T3 ES 97932803 T ES97932803 T ES 97932803T ES 97932803 T ES97932803 T ES 97932803T ES 2176758 T3 ES2176758 T3 ES 2176758T3
Authority
ES
Spain
Prior art keywords
radical
preparation
formula
triazxoles
ciona
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97932803T
Other languages
English (en)
Inventor
Robert Portmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Application granted granted Critical
Publication of ES2176758T3 publication Critical patent/ES2176758T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Silver Salt Photography Or Processing Solution Therefor (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

LA INVENCION SE REFIERE A UN PROCESO PARA LA PREPARACION DE UN COMPUESTO REPRESENTADO POR LA FORMULA (I) EN DONDE, R SUB,1 ES UN RADICAL HETEROAROMATICO O AROMATICO, RADICAL HETEROAROMATICO -ALIFATICO O AROMATICO - ALIFATICO, UN RADICAL CICLOALIFATICO, UN RADICAL CICLOALIFATICO - ALIFATICO O UN RADICAL ALIFATICO. DICHO PROCESO COMPRENDE: HACER REACCIONAR UN COMPUESTO REPRESENTADO POR LA FORMULA (IA) R 1 - N 3 EN DO NDE, R 1 SE DEFINE COMO SE INDICO ANTES, CON EL COMPUESTO REPRESENTADO POR LA FORMULA (IB) EN UN SISTEMA DE DOS FASES. EL COMPUESTO 4 - CIANO -1 - (2,6 - DIFLUOROBENCIL) - 1H - 1,2,3 TRIAZOL ES NUEVO.
ES97932803T 1996-07-11 1997-07-10 Procedimiento para la preparacion de 4-ciona-1,2,3-triazxoles. Expired - Lifetime ES2176758T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH174796 1996-07-11

Publications (1)

Publication Number Publication Date
ES2176758T3 true ES2176758T3 (es) 2002-12-01

Family

ID=4217633

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97932803T Expired - Lifetime ES2176758T3 (es) 1996-07-11 1997-07-10 Procedimiento para la preparacion de 4-ciona-1,2,3-triazxoles.

Country Status (24)

Country Link
US (2) US6156907A (es)
EP (1) EP0918758B1 (es)
JP (1) JP3537147B2 (es)
KR (1) KR100481137B1 (es)
CN (1) CN1083436C (es)
AT (1) ATE216990T1 (es)
AU (1) AU719148B2 (es)
BR (1) BR9710252B1 (es)
CA (1) CA2260065C (es)
CZ (1) CZ294775B6 (es)
DE (1) DE69712342T2 (es)
DK (1) DK0918758T3 (es)
ES (1) ES2176758T3 (es)
HU (1) HU226425B1 (es)
IL (1) IL127665A (es)
NO (1) NO326347B1 (es)
NZ (1) NZ333505A (es)
PL (1) PL189232B1 (es)
PT (1) PT918758E (es)
RU (1) RU2177942C2 (es)
SI (1) SI0918758T1 (es)
SK (1) SK283990B6 (es)
TR (1) TR199900017T2 (es)
WO (1) WO1998002423A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW403740B (en) * 1997-06-10 2000-09-01 Novartis Ag Novel crystal modifications of the compound 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide
CN100335467C (zh) * 2004-06-04 2007-09-05 中国科学院上海有机化学研究所 一锅法区域选择性合成5－碘代－1，4－二取代－1，2，3－三氮唑化合物
JP2012505191A (ja) 2008-10-13 2012-03-01 シプラ・リミテッド ルフィナマイドの製造方法
EP2378879A4 (en) * 2008-12-16 2012-06-06 Merck Sharp & Dohme TRIAZONE DERIVATIVES FOR THE TREATMENT OF MORBUS ALZHEIMER
CN101768124B (zh) * 2008-12-30 2012-01-04 北京本草天源药物研究院 一种药物晶体及其制备方法和用途
JP6108112B2 (ja) * 2010-08-25 2017-04-05 ラオ ダヴルリ，ラマモハン 改良されたルフィナミド調製プロセス
WO2012032540A1 (en) 2010-09-06 2012-03-15 Indoco Remedies Limited Process for preparation of fluorinated triazole compound
CN102219752B (zh) * 2011-04-21 2013-04-10 华润赛科药业有限责任公司 一种1-(2,6-二氟苄基)-1h-1,2,3-三唑-4-甲酰胺的晶型d
WO2014072992A1 (en) 2012-11-12 2014-05-15 Aarti Industries Limited A process for preparing triazole compounds
RU2591206C1 (ru) * 2015-04-14 2016-07-20 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Российский химико-технологический университет имени Д.И. Менделеева (РХТУ им. Д.И. Менделеева)" Замещенные 1-(1-трет-бутил-1н-имидазол-4-ил)-1н-1,2,3-триазолы, способ их получения и фунгицидная композиция на их основе

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS596305B2 (ja) * 1980-03-11 1984-02-10 工業技術院長 １，２，３−トリアゾ−ル誘導体の製造方法
US4789680A (en) * 1982-12-23 1988-12-06 Ciba-Geigy Corporation Aralkyltriazole compounds
FI93544C (fi) * 1985-04-18 1995-04-25 Ciba Geigy Ag Menetelmä fluorattujen, antikonvulsiivisesti vaikuttavien 1-bentsyyli-1H-1,2,3-triatsoliyhdisteiden valmistamiseksi

Also Published As

Publication number Publication date
EP0918758B1 (en) 2002-05-02
BR9710252A (pt) 1999-08-10
HU226425B1 (en) 2008-12-29
PL330914A1 (en) 1999-06-07
US6277999B1 (en) 2001-08-21
NZ333505A (en) 2000-06-23
SI0918758T1 (en) 2002-10-31
ATE216990T1 (de) 2002-05-15
AU719148B2 (en) 2000-05-04
CN1225087A (zh) 1999-08-04
US6156907A (en) 2000-12-05
AU3622097A (en) 1998-02-09
EP0918758A1 (en) 1999-06-02
NO326347B1 (no) 2008-11-17
RU2177942C2 (ru) 2002-01-10
DE69712342T2 (de) 2002-11-14
PT918758E (pt) 2002-09-30
DE69712342D1 (de) 2002-06-06
IL127665A0 (en) 1999-10-28
CZ4299A3 (cs) 1999-04-14
DK0918758T3 (da) 2002-08-19
CZ294775B6 (cs) 2005-03-16
CA2260065A1 (en) 1998-01-22
TR199900017T2 (xx) 1999-04-21
NO990056L (no) 1999-01-07
WO1998002423A1 (en) 1998-01-22
SK283990B6 (sk) 2004-07-07
PL189232B1 (pl) 2005-07-29
KR20000023595A (ko) 2000-04-25
NO990056D0 (no) 1999-01-07
BR9710252B1 (pt) 2010-06-29
HUP9902842A2 (hu) 2000-02-28
CA2260065C (en) 2006-10-17
CN1083436C (zh) 2002-04-24
JP2000507602A (ja) 2000-06-20
IL127665A (en) 2004-03-28
SK2699A3 (en) 1999-06-11
HUP9902842A3 (en) 2000-04-28
KR100481137B1 (ko) 2005-04-08
JP3537147B2 (ja) 2004-06-14

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