BR0011597A - Método para separar compostos orgânicos análogos e resina de troca iÈnica - Google Patents

Método para separar compostos orgânicos análogos e resina de troca iÈnica

Info

Publication number
BR0011597A
BR0011597A BR0011597-5A BR0011597A BR0011597A BR 0011597 A BR0011597 A BR 0011597A BR 0011597 A BR0011597 A BR 0011597A BR 0011597 A BR0011597 A BR 0011597A
Authority
BR
Brazil
Prior art keywords
exchange resin
separating
ion exchange
organic compounds
molecular weight
Prior art date
Application number
BR0011597-5A
Other languages
English (en)
Other versions
BR0011597B1 (pt
Inventor
Yutaka Nishihara
Keiji Honda
Koji Mukai
Norihiro Hashimoto
Hiroshi Hatanaka
Michio Yamashita
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of BR0011597A publication Critical patent/BR0011597A/pt
Publication of BR0011597B1 publication Critical patent/BR0011597B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1814—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns recycling of the fraction to be distributed
    • B01D15/1821—Simulated moving beds
    • B01D15/185—Simulated moving beds characterized by the components to be separated
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/04—Processes using organic exchangers
    • B01J39/05—Processes using organic exchangers in the strongly acidic form
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/08—Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/16—Organic material
    • B01J39/18—Macromolecular compounds
    • B01J39/20—Macromolecular compounds obtained by reactions only involving unsaturated carbon-to-carbon bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/26—Cation exchangers for chromatographic processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2215/00—Separating processes involving the treatment of liquids with adsorbents
    • B01D2215/02—Separating processes involving the treatment of liquids with adsorbents with moving adsorbents
    • B01D2215/023—Simulated moving beds

Abstract

"MéTODO PARA SEPARAR COMPOSTOS ORGâNICOS ANáLOGOS E RESINA DE TROCA IÈNICA". Um método para separar um composto de alto peso molecular contendo lactona tendo um grupo alquila como cadeia lateral de um composto de alto peso molecular contendo lactona tendo um grupo alquenila como sua cadeia lateral, os compostos de alto peso molecular que contém lactona tendo uma estrutura química básica comum, com o uso de uma resina de troca catiónica forte contendo grupo ácido sulfónico pré-tratada com íons de prata.
BRPI0011597-5A 1999-05-25 2000-05-19 método para separar um composto de alto peso molecular contendo lactona. BR0011597B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP14510399 1999-05-25
PCT/JP2000/003251 WO2000071546A1 (en) 1999-05-25 2000-05-19 Method for separating analogous organic compounds

Publications (2)

Publication Number Publication Date
BR0011597A true BR0011597A (pt) 2002-03-05
BR0011597B1 BR0011597B1 (pt) 2011-03-22

Family

ID=15377455

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0011597-5A BR0011597B1 (pt) 1999-05-25 2000-05-19 método para separar um composto de alto peso molecular contendo lactona.

Country Status (27)

Country Link
US (1) US6492513B1 (pt)
EP (1) EP1183261B1 (pt)
JP (1) JP3750527B2 (pt)
KR (1) KR100443048B1 (pt)
CN (1) CN1154651C (pt)
AR (1) AR024068A1 (pt)
AT (1) ATE275150T1 (pt)
AU (1) AU775075C (pt)
BR (1) BR0011597B1 (pt)
CA (1) CA2374999C (pt)
CZ (1) CZ300783B6 (pt)
DE (1) DE60013434T2 (pt)
DK (1) DK1183261T3 (pt)
ES (1) ES2223514T3 (pt)
HK (1) HK1050528A1 (pt)
HU (1) HU228268B1 (pt)
IL (2) IL146285A0 (pt)
MX (1) MXPA01011566A (pt)
NO (1) NO321407B1 (pt)
NZ (1) NZ515462A (pt)
PL (1) PL199512B1 (pt)
PT (1) PT1183261E (pt)
RU (1) RU2234509C2 (pt)
TR (1) TR200103360T2 (pt)
TW (1) TW500725B (pt)
WO (1) WO2000071546A1 (pt)
ZA (1) ZA200109093B (pt)

Families Citing this family (28)

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JP4261365B2 (ja) 2002-02-13 2009-04-30 テバ ジョジセルジャール ザ−トケルエン ムケド レ−スベニュタ−ルシャシャ−グ 生物学的物質からのマクロライドの抽出方法
US7452692B2 (en) 2002-02-13 2008-11-18 Teva Gyógyszergyár Zártkörüen Müködö Részvénytársaság Method for extracting a macrolide from biomatter
AU2003286417A1 (en) * 2003-12-05 2005-06-24 Biocon Limited Process for the purification of macrolides
CA2562805C (en) * 2004-04-12 2014-03-11 Biocon Limited Process for the production of macrolides using a novel strain, streptomyces sp. bicc 7522
CN101031653A (zh) * 2004-09-10 2007-09-05 伊瓦克斯制药有限公司 大环内酯化合物的分离方法
BRPI0515695A (pt) * 2004-09-10 2008-03-04 Ivax Pharmaceuticals Sro processo para isolamento de tacrolimus cristalino
ITMI20042098A1 (it) * 2004-11-03 2005-02-03 Antibioticos Spa Processo per la purificazione di tacrolimus
JP2007519757A (ja) * 2004-12-01 2007-07-19 テバ ジョジセルジャール ザ−トケルエン ムケド レ−スベニュタ−ルシャシャ−グ ピメクロリマスの調製方法
US20060149057A1 (en) * 2004-12-22 2006-07-06 Vilmos Keri Method of purifying macrolides
JP2007527434A (ja) * 2005-01-05 2007-09-27 テバ ジョジセルジャール ザ−トケルエン ムケド レ−スベニュタ−ルシャシャ−グ 非晶質タクロリマス及びその調製
WO2007013017A1 (en) * 2005-07-29 2007-02-01 Ranbaxy Laboratories Limited A process for purification of macrolides
ITMI20051549A1 (it) * 2005-08-05 2007-02-06 Antibioticos Spa Purificazione del tacrolimus su supporti dimorigine vegetale
US7667061B2 (en) 2005-12-16 2010-02-23 Archer-Daniels-Midland Company Method of preparing a composition using argentation chromatography
CA2640161A1 (en) * 2006-03-15 2007-09-20 Teva Gyogyszergyar Zartkoeruen Muekoedoe Reszvenytarsasag Process for purifying tacrolimus
TW200815458A (en) * 2006-03-15 2008-04-01 Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag Process for purifying Tacrolimus
KR100859670B1 (ko) * 2006-09-13 2008-09-23 동국제약 주식회사 타크로리무스를 고수율 및 고순도로 정제하는 방법
KR20090094090A (ko) * 2006-12-28 2009-09-03 리머릭 바이오파르마 인코오포레이티드 치료를 위한 방법 및 조성물
US7947733B2 (en) 2007-07-31 2011-05-24 Limerick Biopharma Phosphorylated pyrone analogs and methods
KR101003042B1 (ko) 2008-03-17 2010-12-21 종근당바이오 주식회사 고순도 타크로리무스의 정제 방법
KR100910165B1 (ko) 2008-09-18 2009-07-30 (주) 제노텍 은 이온 용액 추출을 이용한 불포화 알킬기를 가진 락톤 화합물 정제방법
US20110318277A1 (en) 2010-06-25 2011-12-29 APT Pharmaceuticals, Inc. University of Maryland, Baltimore Tacrolimus compositions for aerosol administration
TWI428167B (zh) * 2011-12-29 2014-03-01 Univ Ishou 一種以模擬移動床分離不同分子量高分子之方法
US9133417B2 (en) 2012-03-23 2015-09-15 The Procter & Gamble Company Liquid cleaning and disinfecting compositions comprising an assymetrically branched amine oxide
US8470755B1 (en) 2012-03-23 2013-06-25 The Procter & Gamble Company Liquid cleaning and disinfecting compositions comprising a zinc inorganic salt
HUE032954T2 (hu) * 2012-07-06 2017-11-28 Godo Shusei Kk Eljárás gyûrûs makrolidvegyület elválasztására
CN106083892B (zh) * 2016-06-13 2019-02-19 杭州中美华东制药有限公司 他克莫司化合物及其制备方法
RU2694354C1 (ru) * 2018-09-25 2019-07-11 Закрытое акционерное общество "БиоХимМак СТ" Способ сорбционно-хроматографического выделения и очистки такролимуса
CN111909176B (zh) * 2020-08-14 2022-03-15 卓和药业集团股份有限公司 一种从他克莫司分离废液中回收子囊霉素、他克莫司8-丙基类似物的方法

Family Cites Families (6)

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JPS4988801A (pt) * 1972-12-29 1974-08-24
US4826603A (en) 1986-09-09 1989-05-02 United States Of America As Represented By The Secretary Of The Air Force Hydrocarbon group-type analyzer system
JPH06185397A (ja) * 1992-12-15 1994-07-05 Mazda Motor Corp 燃料噴射式エンジンの燃料噴射量制御装置
KR970002037B1 (ko) * 1994-12-09 1997-02-21 농촌진흥청 들깨유로부터 α-리놀렌산(ALA)을 분리, 정제하는 방법
US5616595A (en) * 1995-06-07 1997-04-01 Abbott Laboratories Process for recovering water insoluble compounds from a fermentation broth
KR100244164B1 (ko) * 1997-07-15 2000-03-02 김용옥 수용성 고분자-타크로리무스 접합체 화합물 및 그의 제조 방법

Also Published As

Publication number Publication date
KR20020032423A (ko) 2002-05-03
KR100443048B1 (ko) 2004-08-04
IL146285A (en) 2009-11-18
CZ300783B6 (cs) 2009-08-12
DE60013434T2 (de) 2005-01-20
CN1378548A (zh) 2002-11-06
JP2004505749A (ja) 2004-02-26
NO20015579L (no) 2002-01-17
IL146285A0 (en) 2002-07-25
TR200103360T2 (tr) 2002-10-21
CN1154651C (zh) 2004-06-23
AU4615400A (en) 2000-12-12
ZA200109093B (en) 2003-09-23
CA2374999C (en) 2009-03-10
NO20015579D0 (no) 2001-11-15
JP3750527B2 (ja) 2006-03-01
AU775075C (en) 2005-02-24
EP1183261B1 (en) 2004-09-01
HUP0201481A2 (en) 2002-08-28
RU2234509C2 (ru) 2004-08-20
AR024068A1 (es) 2002-09-04
DE60013434D1 (de) 2004-10-07
NZ515462A (en) 2004-05-28
MXPA01011566A (es) 2002-06-04
BR0011597B1 (pt) 2011-03-22
DK1183261T3 (da) 2005-01-17
PT1183261E (pt) 2004-11-30
NO321407B1 (no) 2006-05-08
HK1050528A1 (en) 2003-06-27
TW500725B (en) 2002-09-01
EP1183261A1 (en) 2002-03-06
ES2223514T3 (es) 2005-03-01
AU775075B2 (en) 2004-07-15
WO2000071546A1 (en) 2000-11-30
CZ20014209A3 (cs) 2002-04-17
HU228268B1 (en) 2013-02-28
US6492513B1 (en) 2002-12-10
ATE275150T1 (de) 2004-09-15
PL199512B1 (pl) 2008-09-30
CA2374999A1 (en) 2000-11-30
PL357015A1 (en) 2004-07-12

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP)

Free format text: TRANSFERIDO POR FUSAO DE: FUJISAWA PHARMACEUTICAL CO., LTD.

B25D Requested change of name of applicant approved

Owner name: ASTELLAS PHARMA INC. (JP)

Free format text: ALTERADO DE: YAMANOUCHI PHARMACEUTICAL CO., LTD.

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 22/03/2011, OBSERVADAS AS CONDICOES LEGAIS.

B21A Patent or certificate of addition expired [chapter 21.1 patent gazette]

Free format text: PATENTE EXTINTA EM 22.03.2021