BR0014016A - Método para separar um composto de alto peso molecular contendo lactona - Google Patents
Método para separar um composto de alto peso molecular contendo lactonaInfo
- Publication number
- BR0014016A BR0014016A BR0014016-3A BR0014016A BR0014016A BR 0014016 A BR0014016 A BR 0014016A BR 0014016 A BR0014016 A BR 0014016A BR 0014016 A BR0014016 A BR 0014016A
- Authority
- BR
- Brazil
- Prior art keywords
- molecular weight
- high molecular
- weight compound
- separating
- mixture
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/18—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
"MéTODO PARA SEPARAR UM COMPOSTO DE ALTO PESO MOLECULAR CONTENDO LACTONA". Método para separar um composto de alto peso molecular contendo lactona, compreendendo submeter uma mistura de um composto de alto peso molecular contendo lactona tendo, como sua cadeia lateral, pelo menos um de um grupo alquenila inferior e de um grupo alcoxi inferior e seu(s) composto(s) análogo(s) a qualquer uma ou a ambas as etapas, em qualquer ordem, de uma etapa (A) para adsorver a mistura numa resina de adsorção não-iónica e eluir com um solvente aquoso contendo íons de prata, e uma etapa para adsorver a mistura numa alumina ativa básica e eluir com um solvente orgânico para separar cada um dos compostos.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP11/253813 | 1999-09-08 | ||
JP25381399 | 1999-09-08 | ||
PCT/JP2000/006023 WO2001018007A2 (en) | 1999-09-08 | 2000-09-05 | Method for separating lactone-containing high-molecular weight compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
BR0014016A true BR0014016A (pt) | 2002-05-21 |
BR0014016B1 BR0014016B1 (pt) | 2011-07-12 |
Family
ID=17256507
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0014016-3A BR0014016B1 (pt) | 1999-09-08 | 2000-09-05 | método para separar um composto de alto peso molecular contendo lactona. |
Country Status (24)
Country | Link |
---|---|
US (2) | US6576135B1 (pt) |
EP (1) | EP1210351B1 (pt) |
JP (1) | JP3925198B2 (pt) |
CN (1) | CN1195760C (pt) |
AR (1) | AR025598A1 (pt) |
AT (1) | ATE263773T1 (pt) |
AU (1) | AU779331B2 (pt) |
BR (1) | BR0014016B1 (pt) |
CA (1) | CA2384440C (pt) |
CZ (1) | CZ302625B6 (pt) |
DE (1) | DE60009723T2 (pt) |
DK (1) | DK1210351T3 (pt) |
ES (1) | ES2214307T3 (pt) |
HK (1) | HK1048991A1 (pt) |
HU (1) | HU230126B1 (pt) |
MX (1) | MXPA02002370A (pt) |
NO (1) | NO328422B1 (pt) |
NZ (1) | NZ517473A (pt) |
PL (1) | PL195650B1 (pt) |
PT (1) | PT1210351E (pt) |
RU (1) | RU2245338C2 (pt) |
TR (1) | TR200200593T2 (pt) |
TW (1) | TW553946B (pt) |
WO (1) | WO2001018007A2 (pt) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW553946B (en) * | 1999-09-08 | 2003-09-21 | Fujisawa Pharmaceutical Co | Method for separating lactone-containing high-molecular weight compounds |
US7452692B2 (en) | 2002-02-13 | 2008-11-18 | Teva Gyógyszergyár Zártkörüen Müködö Részvénytársaság | Method for extracting a macrolide from biomatter |
PL374059A1 (en) | 2002-02-13 | 2005-09-19 | Teva Gyogyszergyar Reszvenytarsasag | Method for extracting a macrolide from biomatter |
ES2297481T3 (es) * | 2003-07-24 | 2008-05-01 | Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag | Metodo para purificar macrolidos. |
EP1697383B1 (en) * | 2003-12-05 | 2014-04-23 | Biocon Limited | Process for the purification of tacrolimus |
EP1756290B1 (en) * | 2004-04-12 | 2016-05-04 | Biocon Limited | Streptomyces sp. bicc 7522 and its use for the production of macrolides |
MX2007002808A (es) * | 2004-09-10 | 2007-10-10 | Ivax Pharmaceuticals Sro | Proceso para el aislamiento de tacrolimus cristalino. |
ITMI20042098A1 (it) * | 2004-11-03 | 2005-02-03 | Antibioticos Spa | Processo per la purificazione di tacrolimus |
WO2006060617A1 (en) * | 2004-12-01 | 2006-06-08 | Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag | Ascomycin crystalline forms and preparation thereof |
WO2006069333A1 (en) * | 2004-12-22 | 2006-06-29 | Teva Gyógyszergyár Zàrtköruen Muködo Rèszvènytàrsasàg | Method of purifying macrolides |
JP2007527434A (ja) * | 2005-01-05 | 2007-09-27 | テバ ジョジセルジャール ザ−トケルエン ムケド レ−スベニュタ−ルシャシャ−グ | 非晶質タクロリマス及びその調製 |
WO2007013017A1 (en) * | 2005-07-29 | 2007-02-01 | Ranbaxy Laboratories Limited | A process for purification of macrolides |
ITMI20051549A1 (it) * | 2005-08-05 | 2007-02-06 | Antibioticos Spa | Purificazione del tacrolimus su supporti dimorigine vegetale |
EP1896488B1 (en) * | 2006-03-15 | 2010-05-19 | TEVA Gyógyszergyár Zártkörüen Müködö Részvénytársaság | Process for purifying tacrolimus |
US20080000834A1 (en) * | 2006-03-15 | 2008-01-03 | Ladislav Cvak | Process for purifying Tacrolimus |
JP5602626B2 (ja) * | 2007-06-29 | 2014-10-08 | アーティフィシャル マッスル,インク. | 感覚性フィードバック用途のための電気活性ポリマートランスデューサー |
KR101022067B1 (ko) | 2008-05-30 | 2011-03-17 | 이연제약주식회사 | 고순도 타크로리무스의 회수방법 |
KR100910165B1 (ko) | 2008-09-18 | 2009-07-30 | (주) 제노텍 | 은 이온 용액 추출을 이용한 불포화 알킬기를 가진 락톤 화합물 정제방법 |
WO2011163600A2 (en) | 2010-06-25 | 2011-12-29 | Apt Pharmaceuticals, Inc. | Tacrolimus compositions for aerosol administration |
ES2624229T3 (es) | 2012-07-06 | 2017-07-13 | Godo Shusei Co., Ltd. | Método para separar un compuesto macrólido ciclico |
RU2694354C1 (ru) * | 2018-09-25 | 2019-07-11 | Закрытое акционерное общество "БиоХимМак СТ" | Способ сорбционно-хроматографического выделения и очистки такролимуса |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8406218D0 (en) * | 1984-03-09 | 1984-04-11 | Glaxo Group Ltd | Process |
AU600187B2 (en) * | 1987-12-15 | 1990-08-02 | Unilever Plc | Process for concentrating lactones, as well as the use of the concentrate thus obtained for flavouring foodstuffs |
NO176766C (no) | 1989-02-07 | 1995-05-24 | Meiji Seika Kaisha | Fremgangsmåte for fremstilling av en forbindelse med anthelmintaktivitet |
JPH03191788A (ja) | 1989-12-19 | 1991-08-21 | Nippon Kayaku Co Ltd | 新規抗生物質nk155141およびその製造法 |
TW553946B (en) * | 1999-09-08 | 2003-09-21 | Fujisawa Pharmaceutical Co | Method for separating lactone-containing high-molecular weight compounds |
-
2000
- 2000-08-29 TW TW089117479A patent/TW553946B/zh not_active IP Right Cessation
- 2000-09-05 AU AU68713/00A patent/AU779331B2/en not_active Expired
- 2000-09-05 CZ CZ20020860A patent/CZ302625B6/cs not_active IP Right Cessation
- 2000-09-05 TR TR2002/00593T patent/TR200200593T2/xx unknown
- 2000-09-05 PL PL00353802A patent/PL195650B1/pl unknown
- 2000-09-05 AT AT00956935T patent/ATE263773T1/de active
- 2000-09-05 CN CNB008125864A patent/CN1195760C/zh not_active Expired - Lifetime
- 2000-09-05 DE DE60009723T patent/DE60009723T2/de not_active Expired - Lifetime
- 2000-09-05 ES ES00956935T patent/ES2214307T3/es not_active Expired - Lifetime
- 2000-09-05 EP EP00956935A patent/EP1210351B1/en not_active Expired - Lifetime
- 2000-09-05 DK DK00956935T patent/DK1210351T3/da active
- 2000-09-05 WO PCT/JP2000/006023 patent/WO2001018007A2/en active IP Right Grant
- 2000-09-05 JP JP2001522230A patent/JP3925198B2/ja not_active Expired - Lifetime
- 2000-09-05 NZ NZ517473A patent/NZ517473A/en not_active IP Right Cessation
- 2000-09-05 MX MXPA02002370A patent/MXPA02002370A/es active IP Right Grant
- 2000-09-05 BR BRPI0014016-3A patent/BR0014016B1/pt not_active IP Right Cessation
- 2000-09-05 PT PT00956935T patent/PT1210351E/pt unknown
- 2000-09-05 US US10/069,964 patent/US6576135B1/en not_active Expired - Lifetime
- 2000-09-05 HU HU0203196A patent/HU230126B1/hu unknown
- 2000-09-05 CA CA002384440A patent/CA2384440C/en not_active Expired - Lifetime
- 2000-09-05 RU RU2002108718/04A patent/RU2245338C2/ru active
- 2000-09-07 AR ARP000104697A patent/AR025598A1/es active IP Right Grant
-
2002
- 2002-03-01 NO NO20021024A patent/NO328422B1/no not_active IP Right Cessation
-
2003
- 2003-02-17 HK HK03101134A patent/HK1048991A1/xx unknown
- 2003-04-07 US US10/407,168 patent/US6881341B2/en not_active Expired - Lifetime
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25A | Requested transfer of rights approved |
Owner name: YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) Free format text: TRANSFERIDO POR FUSAO DE: FUJISAWA PHARMACEUTICAL CO., LTD. |
|
B25D | Requested change of name of applicant approved |
Owner name: ASTELLAS PHARMA INC. (JP) Free format text: ALTERADO DE: YAMANOUCHI PHARMACEUTICAL CO., LTD. |
|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 12/07/2011, OBSERVADAS AS CONDICOES LEGAIS. |
|
B21A | Patent or certificate of addition expired [chapter 21.1 patent gazette] |
Free format text: PATENTE EXTINTA EM 12.07.2021 |