NZ716420A - Fused heterocyclic compounds as sodium channel modulators - Google Patents
Fused heterocyclic compounds as sodium channel modulatorsInfo
- Publication number
- NZ716420A NZ716420A NZ716420A NZ71642012A NZ716420A NZ 716420 A NZ716420 A NZ 716420A NZ 716420 A NZ716420 A NZ 716420A NZ 71642012 A NZ71642012 A NZ 71642012A NZ 716420 A NZ716420 A NZ 716420A
- Authority
- NZ
- New Zealand
- Prior art keywords
- sodium channel
- compounds
- heterocyclic compounds
- fused heterocyclic
- channel modulators
- Prior art date
Links
- 108010052164 Sodium Channels Proteins 0.000 title abstract 2
- 102000018674 Sodium Channels Human genes 0.000 title abstract 2
- 150000002391 heterocyclic compounds Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- QJYIRGGTCVQALQ-UHFFFAOYSA-N 2-[(4-cyclopropylpyrimidin-2-yl)methyl]-7-[4-(trifluoromethoxy)phenyl]phthalazin-1-one Chemical compound C1=CC(OC(F)(F)F)=CC=C1C1=CC=C(C=NN(CC=2N=C(C=CN=2)C2CC2)C2=O)C2=C1 QJYIRGGTCVQALQ-UHFFFAOYSA-N 0.000 abstract 1
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
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- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/10—Spiro-condensed systems
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- C07D253/04—1,2,3-Triazines
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
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- Other In-Based Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
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2013
- 2013-10-24 IL IL229045A patent/IL229045A0/en unknown
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2015
- 2015-07-24 US US14/808,296 patent/US9403782B2/en active Active
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2016
- 2016-04-21 AU AU2016202535A patent/AU2016202535B2/en not_active Ceased
- 2016-06-21 US US15/188,701 patent/US9682998B2/en active Active
- 2016-12-19 HK HK16114404.3A patent/HK1238627A1/zh unknown
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2018
- 2018-07-19 HK HK18109345.3A patent/HK1249902A1/en unknown
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