|
US3126375A
(en)
|
|
1964-03-24 |
|
Chioacyl |
|
US2789118A
(en)
|
1956-03-30 |
1957-04-16 |
American Cyanamid Co |
16-alpha oxy-belta1, 4-pregnadienes
|
|
US2990401A
(en)
|
1958-06-18 |
1961-06-27 |
American Cyanamid Co |
11-substituted 16alpha, 17alpha-substituted methylenedioxy steroids
|
|
US3048581A
(en)
|
1960-04-25 |
1962-08-07 |
Olin Mathieson |
Acetals and ketals of 16, 17-dihydroxy steroids
|
|
US3749712A
(en)
|
1970-09-25 |
1973-07-31 |
Sigma Tau Ind Farmaceuti |
Triamcinolone acetonide esters and process for their preparation
|
|
SE378110B
(enExample)
|
1972-05-19 |
1975-08-18 |
Bofors Ab |
|
|
US3996359A
(en)
|
1972-05-19 |
1976-12-07 |
Ab Bofors |
Novel stereoisomeric component A of stereoisomeric mixtures of 2'-unsymmetrical 16,17-methylenedioxy steroid 21-acylates, compositions thereof, and method of treating therewith
|
|
SE378109B
(enExample)
|
1972-05-19 |
1975-08-18 |
Bofors Ab |
|
|
US4319039A
(en)
|
1979-06-15 |
1982-03-09 |
Merck & Co., Inc. |
Preparation of ammonium salt of hypocholesteremic fermentation product
|
|
US4294926A
(en)
|
1979-06-15 |
1981-10-13 |
Merck & Co., Inc. |
Hypocholesteremic fermentation products and process of preparation
|
|
US4231938A
(en)
|
1979-06-15 |
1980-11-04 |
Merck & Co., Inc. |
Hypocholesteremic fermentation products and process of preparation
|
|
US4444784A
(en)
|
1980-08-05 |
1984-04-24 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
|
MX7065E
(es)
|
1980-06-06 |
1987-04-10 |
Sankyo Co |
Un procedimiento microbiologico para preparar derivados de ml-236b
|
|
JPS5889191A
(ja)
|
1981-11-20 |
1983-05-27 |
Sankyo Co Ltd |
３−ヒドロキシ−ｍｌ−２３６ｂ誘導体の製造法
|
|
US5354772A
(en)
|
1982-11-22 |
1994-10-11 |
Sandoz Pharm. Corp. |
Indole analogs of mevalonolactone and derivatives thereof
|
|
US4911165A
(en)
|
1983-01-12 |
1990-03-27 |
Ethicon, Inc. |
Pliabilized polypropylene surgical filaments
|
|
US5215738A
(en)
|
1985-05-03 |
1993-06-01 |
Sri International |
Benzamide and nicotinamide radiosensitizers
|
|
US5041653A
(en)
|
1985-05-03 |
1991-08-20 |
Sri International |
Substituted benzamide radiosensitizers
|
|
US5032617A
(en)
|
1985-05-03 |
1991-07-16 |
Sri International |
Substituted benzamide radiosensitizers
|
|
US4681893A
(en)
|
1986-05-30 |
1987-07-21 |
Warner-Lambert Company |
Trans-6-[2-(3- or 4-carboxamido-substituted pyrrol-1-yl)alkyl]-4-hydroxypyran-2-one inhibitors of cholesterol synthesis
|
|
US4782084A
(en)
|
1987-06-29 |
1988-11-01 |
Merck & Co., Inc. |
HMG-COA reductase inhibitors
|
|
US4885314A
(en)
|
1987-06-29 |
1989-12-05 |
Merck & Co., Inc. |
Novel HMG-CoA reductase inhibitors
|
|
US4820850A
(en)
|
1987-07-10 |
1989-04-11 |
Merck & Co., Inc. |
Process for α-C-alkylation of the 8-acyl group on mevinolin and analogs thereof
|
|
US5030447A
(en)
|
1988-03-31 |
1991-07-09 |
E. R. Squibb & Sons, Inc. |
Pharmaceutical compositions having good stability
|
|
US5180589A
(en)
|
1988-03-31 |
1993-01-19 |
E. R. Squibb & Sons, Inc. |
Pravastatin pharmaceuatical compositions having good stability
|
|
US4916239A
(en)
|
1988-07-19 |
1990-04-10 |
Merck & Co., Inc. |
Process for the lactonization of mevinic acids and analogs thereof
|
|
EP0360390A1
(en)
|
1988-07-25 |
1990-03-28 |
Glaxo Group Limited |
Spirolactam derivatives
|
|
US5290946A
(en)
|
1988-10-13 |
1994-03-01 |
Sandoz Ltd. |
Processes for the synthesis of 3-(substituted indolyl-2-yl)propenaldehydes
|
|
US5118853A
(en)
|
1988-10-13 |
1992-06-02 |
Sandoz Ltd. |
Processes for the synthesis of 3-disubstituted aminoacroleins
|
|
WO1990005525A1
(en)
|
1988-11-23 |
1990-05-31 |
Pfizer Inc. |
Quinuclidine derivatives as substance p antagonists
|
|
US4929437A
(en)
|
1989-02-02 |
1990-05-29 |
Merck & Co., Inc. |
Coenzyme Q10 with HMG-CoA reductase inhibitors
|
|
US5164372A
(en)
|
1989-04-28 |
1992-11-17 |
Fujisawa Pharmaceutical Company, Ltd. |
Peptide compounds having substance p antagonism, processes for preparation thereof and pharmaceutical composition comprising the same
|
|
US5189164A
(en)
|
1989-05-22 |
1993-02-23 |
Sandoz Ltd. |
Processes for the synthesis of syn-(E)-3,5-dihydroxy-7-substituted hept-6-enoic and heptanoic acids and derivatives and intermediates thereof
|
|
FI94339C
(fi)
|
1989-07-21 |
1995-08-25 |
Warner Lambert Co |
Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi
|
|
PH27357A
(en)
|
1989-09-22 |
1993-06-21 |
Fujisawa Pharmaceutical Co |
Pyrazole derivatives and pharmaceutical compositions comprising the same
|
|
IE903957A1
(en)
|
1989-11-06 |
1991-05-08 |
Sanofi Sa |
Aromatic amine compounds, their method of preparation and¹pharmaceutical compositions in which they are present
|
|
FR2654726B1
(fr)
|
1989-11-23 |
1992-02-14 |
Rhone Poulenc Sante |
Nouveaux derives de l'isoindolone et leur preparation.
|
|
FR2654725B1
(fr)
|
1989-11-23 |
1992-02-14 |
Rhone Poulenc Sante |
Nouveaux derives de l'isoindolone, leur preparation et les compositions pharmaceutiques qui les contiennent.
|
|
GB8929070D0
(en)
|
1989-12-22 |
1990-02-28 |
Fujisawa Pharmaceutical Co |
Peptide compounds,processes for preparation thereof and pharmaceutical composition comprising the same
|
|
US5232929A
(en)
|
1990-11-28 |
1993-08-03 |
Pfizer Inc. |
3-aminopiperidine derivatives and related nitrogen containing heterocycles and pharmaceutical compositions and use
|
|
WO1991009844A1
(en)
|
1990-01-04 |
1991-07-11 |
Pfizer Inc. |
Substance p antagonists
|
|
EP0515681A4
(en)
|
1990-02-15 |
1993-12-29 |
Fujisawa Pharmaceutical Co., Ltd. |
Peptide compound
|
|
US5420245A
(en)
|
1990-04-18 |
1995-05-30 |
Board Of Regents, The University Of Texas |
Tetrapeptide-based inhibitors of farnesyl transferase
|
|
GB9011833D0
(en)
|
1990-05-25 |
1990-07-18 |
Collins Mary K L |
Inhibition of viral infection
|
|
EP0532527B1
(en)
|
1990-06-01 |
1994-11-09 |
Pfizer Inc. |
3-amino-2-aryl quinuclidines, process for their preparation and pharmaceutical compositions containing them
|
|
DK0540526T3
(da)
|
1990-07-23 |
1995-04-18 |
Pfizer |
Quinuclidinderivater
|
|
AU687754B2
(en)
|
1990-08-31 |
1998-03-05 |
Warner-Lambert Company |
Tachykinin antagonists
|
|
AU651145B2
(en)
|
1990-09-28 |
1994-07-14 |
Pfizer Inc. |
Fused ring analogs of nitrogen containing nonaromatic heterocycles
|
|
GB9023116D0
(en)
|
1990-10-24 |
1990-12-05 |
Fujisawa Pharmaceutical Co |
Peptide compounds,processes for preparation thereof and pharmaceutical composition comprising the same
|
|
DE69114117T2
(de)
|
1990-12-21 |
1996-03-21 |
Fujisawa Pharmaceutical Co |
Neue Verwendung von Peptidderivat.
|
|
EP0566589A1
(en)
|
1991-01-10 |
1993-10-27 |
Pfizer Inc. |
N-alkyl quinuclidinium salts as substance p antagonists
|
|
ATE154354T1
(de)
|
1991-02-11 |
1997-06-15 |
Merck Sharp & Dohme |
Azabicyclische verbindungen, diese enthaltende pharmazeutische zubereitungen und ihre therapeutische verwendung
|
|
EP0573522B1
(en)
|
1991-03-01 |
1994-12-14 |
Pfizer Inc. |
1-azabicyclo[3.2.2]nonan-3-amine derivatives
|
|
US5747469A
(en)
|
1991-03-06 |
1998-05-05 |
Board Of Regents, The University Of Texas System |
Methods and compositions comprising DNA damaging agents and p53
|
|
PL169993B1
(pl)
|
1991-03-26 |
1996-09-30 |
Pfizer |
Sposób wytwarzania podstawionych piperydyn PL PL PL PL
|
|
FR2677361A1
(fr)
|
1991-06-04 |
1992-12-11 |
Adir |
Nouveaux peptides et pseudopeptides, derives de tachykinines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
|
|
FR2676055B1
(fr)
|
1991-05-03 |
1993-09-03 |
Sanofi Elf |
Composes polycycliques amines et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
|
|
FR2676053B1
(fr)
|
1991-05-03 |
1993-08-27 |
Sanofi Elf |
Nouveaux composes dialkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
|
|
FR2676443B1
(fr)
|
1991-05-17 |
1993-08-06 |
Rhone Poulenc Rorer Sa |
Nouveaux derives de perhydroisoindole et leur preparation.
|
|
FR2676446B1
(fr)
|
1991-05-17 |
1993-08-06 |
Rhone Poulenc Rorer Sa |
Nouveaux derives du thiopyranopyrrole, leur preparation et les compositions pharmaceutiques qui les contiennent.
|
|
FR2676447B1
(fr)
|
1991-05-17 |
1993-08-06 |
Rhone Poulenc Rorer Sa |
Nouveaux derives du thiopyranopyrrole et leur preparation.
|
|
FR2676442B1
(fr)
|
1991-05-17 |
1993-08-06 |
Rhone Poulenc Rorer Sa |
Nouveau derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent.
|
|
WO1992020661A1
(en)
|
1991-05-22 |
1992-11-26 |
Merck & Co., Inc. |
N, n-diacylpiperazines
|
|
DK0585328T3
(da)
|
1991-05-22 |
2002-02-11 |
Pfizer |
Substituerede 3-aminoquinuclidiner
|
|
SK278788B6
(sk)
|
1991-05-31 |
1998-02-04 |
Pfizer Inc. |
Chinuklidínové deriváty, spôsob ich prípravy a pou
|
|
GB9113219D0
(en)
|
1991-06-19 |
1991-08-07 |
Fujisawa Pharmaceutical Co |
Peptide compound,processes for preparation thereof and pharmaceutical composition comprising the same
|
|
EP0589924B1
(en)
|
1991-06-20 |
1996-09-04 |
Pfizer Inc. |
Fluoroalkoxybenzylamino derivatives of nitrogen containing heterocycles
|
|
TW202432B
(enExample)
|
1991-06-21 |
1993-03-21 |
Pfizer |
|
|
US5288730A
(en)
|
1991-06-24 |
1994-02-22 |
Merck Sharp & Dohme Limited |
Azabicyclic compounds, pharmaceutical compositions containing them and their use in therapy
|
|
JPH06509332A
(ja)
|
1991-07-05 |
1994-10-20 |
メルク シヤープ エンド ドーム リミテツド |
芳香族化合物、それらを含む医薬組成物、及び治療におけるそれらの使用
|
|
EP0536817A1
(en)
|
1991-07-05 |
1993-04-14 |
MERCK SHARP & DOHME LTD. |
Azabicyclic compounds as tachykinin antagonists
|
|
EP0593559A1
(en)
|
1991-07-05 |
1994-04-27 |
MERCK SHARP & DOHME LTD. |
Aromatic compounds, pharmaceutical compositions containing them and their use in therapy
|
|
US5495047A
(en)
|
1991-07-10 |
1996-02-27 |
Merck, Sharp & Dohme (Ltd.) |
Fused tricyclic compounds, pharmaceutical compositions containing them and their use in therapy
|
|
ATE133658T1
(de)
|
1991-07-10 |
1996-02-15 |
Merck Sharp & Dohme |
Aromatische verbindungen diese enthaltende pharmazeutische zusammensetzungen und ihre therapeutische verwendung
|
|
MY110227A
(en)
|
1991-08-12 |
1998-03-31 |
Ciba Geigy Ag |
1-acylpiperindine compounds.
|
|
CA2112397A1
(en)
|
1991-08-20 |
1993-03-04 |
Raymond Baker |
Azacyclic compounds, processes for their preparation and pharmaceutical compositions containing them
|
|
ATE195867T1
(de)
|
1991-09-20 |
2000-09-15 |
Glaxo Group Ltd |
Neue medizinische indikation für tachykinin- antagonisten
|
|
US5527808A
(en)
|
1991-09-26 |
1996-06-18 |
Pfizer Inc. |
Fused tricyclic nitrogen containing heterocycles
|
|
US5652260A
(en)
|
1991-10-22 |
1997-07-29 |
Octamer, Inc. |
Adenosine diphosphoribose polymerase binding nitroso aromatic compound useful as retroviral inactivating agents, anti-retroviral agents and anti-tumor agents
|
|
JP2553020B2
(ja)
|
1991-11-07 |
1996-11-13 |
吉富製薬株式会社 |
キヌクリジン化合物およびその医薬用途
|
|
DK0613458T3
(da)
|
1991-11-12 |
1998-02-09 |
Pfizer |
Acykliske ethylendiaminderivater som substans P receptorantagonister
|
|
CA2083891A1
(en)
|
1991-12-03 |
1993-06-04 |
Angus Murray Macleod |
Heterocyclic compounds, compositions containing them and their use in therapy
|
|
HU9203780D0
(en)
|
1991-12-12 |
1993-03-29 |
Sandoz Ag |
Stabilized pharmaceutical products of hmg-coa reductase inhibitor and method for producing them
|
|
GB9200535D0
(en)
|
1992-01-10 |
1992-02-26 |
Fujisawa Pharmaceutical Co |
New compound
|
|
GB9201179D0
(en)
|
1992-01-21 |
1992-03-11 |
Glaxo Group Ltd |
Chemical compounds
|
|
US5328927A
(en)
|
1992-03-03 |
1994-07-12 |
Merck Sharpe & Dohme, Ltd. |
Hetercyclic compounds, processes for their preparation and pharmaceutical compositions containing them
|
|
JP2656702B2
(ja)
|
1992-03-23 |
1997-09-24 |
ファイザー製薬株式会社 |
ペプチド性キヌクリジン
|
|
FR2689888B1
(fr)
|
1992-04-10 |
1994-06-10 |
Rhone Poulenc Rorer Sa |
Nouveaux derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent.
|
|
EP0636130A1
(en)
|
1992-04-15 |
1995-02-01 |
Merck Sharp & Dohme Ltd. |
Azacyclic compounds
|
|
GB2266529A
(en)
|
1992-05-01 |
1993-11-03 |
Merck Sharp & Dohme |
Tetrahydroisoquinoline derivatives
|
|
PT641328E
(pt)
|
1992-05-18 |
2002-04-29 |
Pfizer |
Derivados aza-biciclicos em ponte como antagonistas da substancia p
|
|
GB9211193D0
(en)
|
1992-05-27 |
1992-07-08 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
US5719147A
(en)
|
1992-06-29 |
1998-02-17 |
Merck & Co., Inc. |
Morpholine and thiomorpholine tachykinin receptor antagonists
|
|
IL106142A
(en)
|
1992-06-29 |
1997-03-18 |
Merck & Co Inc |
Morpholine and thiomorpholine tachykinin receptor antagonists, their preparation and pharmaceutical compositions containing them
|
|
US5637699A
(en)
|
1992-06-29 |
1997-06-10 |
Merck & Co., Inc. |
Process for preparing morpholine tachykinin receptor antagonists
|
|
WO1994001402A1
(en)
|
1992-07-13 |
1994-01-20 |
Merck Sharp & Dohme Limited |
Heterocyclic amide derivatives as tachykinin derivatives
|
|
WO1994002595A1
(en)
|
1992-07-17 |
1994-02-03 |
Ribozyme Pharmaceuticals, Inc. |
Method and reagent for treatment of animal diseases
|
|
GB2268931A
(en)
|
1992-07-22 |
1994-01-26 |
Merck Sharp & Dohme |
Azabicyclic tachykinin-receptor antagonists
|
|
ATE173725T1
(de)
|
1992-07-28 |
1998-12-15 |
Merck Sharp & Dohme |
Azazyklische verbindungen
|
|
GB2269170A
(en)
|
1992-07-29 |
1994-02-02 |
Merck Sharp & Dohme |
Azatricyclic tachykinin antagonists
|
|
WO1994003429A1
(en)
|
1992-07-31 |
1994-02-17 |
Merck Sharp & Dohme Limited |
Substituted amines as tachykinin receptor antagonists
|
|
JPH07506379A
(ja)
|
1992-08-04 |
1995-07-13 |
ファイザー・インコーポレーテッド |
物質ｐ受容体アンタゴニストとしての３−ベンジルアミノ−２−フェニル−ピペリジン
|
|
GB9216911D0
(en)
|
1992-08-10 |
1992-09-23 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
JP2909214B2
(ja)
|
1992-08-19 |
1999-06-23 |
フアイザー・インコーポレイテツド |
置換ベンジルアミノ窒素含有非芳香族複素環化合物
|
|
US5387595A
(en)
|
1992-08-26 |
1995-02-07 |
Merck & Co., Inc. |
Alicyclic compounds as tachykinin receptor antagonists
|
|
NO179904C
(no)
|
1992-09-04 |
1997-01-08 |
Takeda Chemical Industries Ltd |
Kondenserte heterocykliske forbindelser og deres anvendelse
|
|
AU4973693A
(en)
|
1992-09-10 |
1994-03-29 |
Merck Sharp & Dohme Limited |
Alcohols and ethers with aromatic substituents as tachykinin-antagonists
|
|
GB9220286D0
(en)
|
1992-09-25 |
1992-11-11 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
JP2656699B2
(ja)
|
1992-10-21 |
1997-09-24 |
ファイザー製薬株式会社 |
置換ベンジルアミノキヌクリジン
|
|
GB9222262D0
(en)
|
1992-10-23 |
1992-12-09 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB9222486D0
(en)
|
1992-10-26 |
1992-12-09 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
JP2656700B2
(ja)
|
1992-10-28 |
1997-09-24 |
ファイザー製薬株式会社 |
置換キヌクリジン誘導体
|
|
ES2141174T3
(es)
|
1992-10-28 |
2000-03-16 |
Merck Sharp & Dohme |
4-arilmetiloximetil piperidinas como antagonistas de taquiquinina.
|
|
WO1994010167A1
(en)
|
1992-10-30 |
1994-05-11 |
Merck Sharp & Dohme Limited |
Tachykinin antagonists
|
|
US5886009A
(en)
|
1992-11-12 |
1999-03-23 |
Pfizer Inc. |
Quinuclidine derivative as a substance P antagonist
|
|
US5261188A
(en)
|
1992-11-23 |
1993-11-16 |
The Standard Products Company |
Belt weatherstrip with bulb
|
|
ATE194340T1
(de)
|
1992-12-10 |
2000-07-15 |
Pfizer |
Aminomethylen substituierte heterocyclische verbindungen und ihre verwendung alssubstanz p antagonisten
|
|
US5604260A
(en)
|
1992-12-11 |
1997-02-18 |
Merck Frosst Canada Inc. |
5-methanesulfonamido-1-indanones as an inhibitor of cyclooxygenase-2
|
|
US5661162A
(en)
|
1992-12-14 |
1997-08-26 |
Merck Sharp & Dohme Limited |
4-aminomethyl/thiomethyl/sulfonylmethyl-4-phenylpiperdines as tachykinin receptor antagonists
|
|
GB9226581D0
(en)
|
1992-12-21 |
1993-02-17 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
EP0604181A1
(en)
|
1992-12-21 |
1994-06-29 |
Eli Lilly And Company |
Antitumor compositions and method of treatment
|
|
GB9300051D0
(en)
|
1993-01-04 |
1993-03-03 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
EP0759432A1
(en)
|
1993-01-15 |
1997-02-26 |
G.D. Searle & Co. |
Use of medicaments containing 3,4-diaryl furans and analogs thereof for treating a skin-related condition
|
|
EP0610793A1
(en)
|
1993-02-08 |
1994-08-17 |
Takeda Chemical Industries, Ltd. |
Tetracyclic morpholine derivatives and their use or analgesics
|
|
JPH08506823A
(ja)
|
1993-02-18 |
1996-07-23 |
メルク シヤープ エンド ドーム リミテツド |
アザ環式化合物、該化合物を含む組成物及びタキキニン拮抗剤としての該化合物の使用
|
|
AU6140694A
(en)
|
1993-02-22 |
1994-09-14 |
Merck Sharp & Dohme Limited |
Aromatic compounds, compositions containing them and their use in therapy
|
|
WO1994019357A1
(en)
|
1993-02-23 |
1994-09-01 |
Merrell Dow Pharmaceuticals Inc. |
Farnesyl:protein transferase inhibitors as anticancer agents
|
|
US5298627A
(en)
|
1993-03-03 |
1994-03-29 |
Warner-Lambert Company |
Process for trans-6-[2-(substituted-pyrrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis
|
|
ATE166650T1
(de)
|
1993-03-04 |
1998-06-15 |
Pfizer |
Spiroazacyclischderivate als substanz p antagonisten
|
|
US5409944A
(en)
|
1993-03-12 |
1995-04-25 |
Merck Frosst Canada, Inc. |
Alkanesulfonamido-1-indanone derivatives as inhibitors of cyclooxygenase
|
|
CA2118985A1
(en)
|
1993-04-02 |
1994-10-03 |
Dinesh V. Patel |
Heterocyclic inhibitors of farnesyl protein transferase
|
|
US5496833A
(en)
|
1993-04-13 |
1996-03-05 |
Merck Sharp & Dohme Limited |
Piperidine tachykinin receptor antagonists
|
|
HU224496B1
(hu)
|
1993-05-06 |
2005-10-28 |
Merrel Dow Pharmaceuticals Inc. |
Pirrolidin-3-il-alkil-piperidin-származékok és e vegyületeket tartalmazó gyógyászati készítmények
|
|
EP0698015A1
(en)
|
1993-05-14 |
1996-02-28 |
Genentech, Inc. |
Preparation of n-cyanodithioimino-carbonates and 3-mercapto-5-amino-1h-1,2,4-triazole
|
|
US5602098A
(en)
|
1993-05-18 |
1997-02-11 |
University Of Pittsburgh |
Inhibition of farnesyltransferase
|
|
IL109646A0
(en)
|
1993-05-19 |
1994-08-26 |
Pfizer |
Heteroatom substituted alkyl benzylamino-quinuclidines
|
|
US5380738A
(en)
|
1993-05-21 |
1995-01-10 |
Monsanto Company |
2-substituted oxazoles further substituted by 4-fluorophenyl and 4-methylsulfonylphenyl as antiinflammatory agents
|
|
EP0702681A1
(en)
|
1993-06-07 |
1996-03-27 |
Merck & Co. Inc. |
Spiro-substituted azacycles as neurokinin antagonists
|
|
GB9602877D0
(en)
|
1996-02-13 |
1996-04-10 |
Merck Frosst Canada Inc |
3,4-Diaryl-2-hydroxy-2,5- dihydrofurans as prodrugs to cox-2 inhibitors
|
|
US5474995A
(en)
|
1993-06-24 |
1995-12-12 |
Merck Frosst Canada, Inc. |
Phenyl heterocycles as cox-2 inhibitors
|
|
US5436265A
(en)
|
1993-11-12 |
1995-07-25 |
Merck Frosst Canada, Inc. |
1-aroyl-3-indolyl alkanoic acids and derivatives thereof useful as anti-inflammatory agents
|
|
EP0634402A1
(en)
|
1993-07-14 |
1995-01-18 |
Takeda Chemical Industries, Ltd. |
Isochinolinone derivatives, their production and use
|
|
ES2121213T3
(es)
|
1993-07-15 |
1998-11-16 |
Pfizer |
Benciloxiquinuclidinas como antagonistas de la sustancia p.
|
|
GB9315808D0
(en)
|
1993-07-30 |
1993-09-15 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
TW365603B
(en)
|
1993-07-30 |
1999-08-01 |
Rhone Poulenc Rorer Sa |
Novel perhydroisoindole derivatives, their preparation and pharmaceutical compositions which contain them
|
|
GB9317987D0
(en)
|
1993-08-26 |
1993-10-13 |
Glaxo Group Ltd |
Chemical compounds
|
|
WO1995007908A1
(en)
|
1993-09-17 |
1995-03-23 |
Pfizer Inc. |
Heteroarylamino and heteroarylsulfonamido substituted 3-benzylaminomethyl piperidines and related compounds
|
|
DE69433744T2
(de)
|
1993-09-17 |
2004-10-14 |
Pfizer Inc. |
3-amino-5-carboxy-substituierte piperidine und 3-amino-4-carboxy-substituierte pyrrolidine als tachykinin-antagonisten
|
|
WO1995008542A1
(en)
|
1993-09-22 |
1995-03-30 |
Kyowa Hakko Kogyo Co., Ltd. |
Farnesyltransferase inhibitor
|
|
IS4208A
(is)
|
1993-09-22 |
1995-03-23 |
Glaxo Group Limited |
3-(tetrazólýl-benzyl)amínó-piperadidín afleiður
|
|
IL111235A
(en)
|
1993-10-15 |
2001-03-19 |
Schering Plough Corp |
Medicinal preparations for inhibiting protein G activity and for the treatment of malignant diseases, containing tricyclic compounds, some such new compounds and a process for the preparation of some of them
|
|
IL111257A0
(en)
|
1993-10-15 |
1994-12-29 |
Schering Corp |
Tricyclic sulfonamide compounds useful for inhibition of g-protein function and for treatment of proliferative diseases
|
|
US5719148A
(en)
|
1993-10-15 |
1998-02-17 |
Schering Corporation |
Tricyclic amide and urea compounds useful for inhibition of g-protein function and for treatment of proliferative diseases
|
|
AU699043B2
(en)
|
1993-10-15 |
1998-11-19 |
Schering Corporation |
Tricyclic carbamate compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
|
|
US5721236A
(en)
|
1993-10-15 |
1998-02-24 |
Schering Corporation |
Tricyclic carbamate compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
|
|
US5661152A
(en)
|
1993-10-15 |
1997-08-26 |
Schering Corporation |
Tricyclic sulfonamide compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
|
|
DK0725790T3
(da)
|
1993-10-25 |
2001-06-11 |
Parke Davis & Co |
Substituerede tetra- og pentapeptidinhibitorer af proteinfarnesyltransferase
|
|
WO1995011880A1
(en)
|
1993-10-27 |
1995-05-04 |
Merck Sharp & Dohme Limited |
Substituted amides as tachykinin antagonists
|
|
US5344991A
(en)
|
1993-10-29 |
1994-09-06 |
G.D. Searle & Co. |
1,2 diarylcyclopentenyl compounds for the treatment of inflammation
|
|
DE69417012T2
(de)
|
1993-11-04 |
1999-10-07 |
Abbott Laboratories, Abbott Park |
Cyclobutan-derivate als inhibitoren der squalen-synthetase und der protein-farnesyltransferase
|
|
US5783593A
(en)
|
1993-11-04 |
1998-07-21 |
Abbott Laboratories |
Inhibitors of squalene synthetase and protein farnesyltransferase
|
|
FI961819A7
(fi)
|
1993-11-05 |
1996-04-29 |
Warner Lambert Co |
Proteiini:farnesyylitransferaasin substituoidut di- ja tripeptidi-inhi biittorit
|
|
US6403577B1
(en)
|
1993-11-17 |
2002-06-11 |
Eli Lilly And Company |
Hexamethyleneiminyl tachykinin receptor antagonists
|
|
US5466823A
(en)
|
1993-11-30 |
1995-11-14 |
G.D. Searle & Co. |
Substituted pyrazolyl benzenesulfonamides
|
|
IT1271462B
(it)
|
1993-12-03 |
1997-05-28 |
Menarini Farma Ind |
Antagonisti delle tachichinine,procedimento per la loro preparazione e loro impiego in formulazioni farmaceutiche.
|
|
US5484799A
(en)
|
1993-12-09 |
1996-01-16 |
Abbott Laboratories |
Antifungal dorrigocin derivatives
|
|
IL111960A
(en)
|
1993-12-17 |
1999-12-22 |
Merck & Co Inc |
Morpholines and thiomorpholines their preparation and pharmaceutical compositions containing them
|
|
EP0736007A4
(en)
|
1993-12-21 |
1997-03-19 |
Lilly Co Eli |
NON-PEPTIDE ANTAGONISTS OF TACHYKININ RECEPTORS
|
|
WO1995018129A1
(en)
|
1993-12-29 |
1995-07-06 |
Pfizer Inc. |
Diazabicyclic neurokinin antagonists
|
|
SK283070B6
(sk)
|
1993-12-29 |
2003-02-04 |
Merck Sharp & Dohme Limited |
Substituované morfolínové deriváty, spôsob ich výroby, farmaceutický prostriedok s ich obsahom a ich použitie
|
|
WO1995019344A1
(en)
|
1994-01-13 |
1995-07-20 |
Merck Sharp & Dohme Limited |
Gem-disubstituted azacyclic tachykinin antagonists
|
|
EP0741704A1
(en)
|
1994-01-28 |
1996-11-13 |
MERCK SHARP & DOHME LTD. |
Aralkylamino substituted azacyclic therapeutic agents
|
|
US5393790A
(en)
|
1994-02-10 |
1995-02-28 |
G.D. Searle & Co. |
Substituted spiro compounds for the treatment of inflammation
|
|
GB9402688D0
(en)
|
1994-02-11 |
1994-04-06 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
US5610165A
(en)
|
1994-02-17 |
1997-03-11 |
Merck & Co., Inc. |
N-acylpiperidine tachykinin antagonists
|
|
IL112778A0
(en)
|
1994-03-04 |
1995-05-26 |
Merck & Co Inc |
Substituted heterocycles, their preparation and pharmaceutical compositions containing them
|
|
WO1995024612A1
(de)
|
1994-03-07 |
1995-09-14 |
International Business Machines Corporation |
Verfahren und vorrichtung zur schnellen interpolation von zwischenwerten aus periodischen phasenverschobenen signalen und zur erkennung von defekten in einem drehkörper
|
|
GB9404485D0
(en)
|
1994-03-09 |
1994-04-20 |
Cancer Res Campaign Tech |
Benzamide analogues
|
|
CN1151156A
(zh)
|
1994-03-15 |
1997-06-04 |
卫材株式会社 |
异戊二烯基转移酶抑制剂
|
|
FR2718136B1
(fr)
|
1994-03-29 |
1996-06-21 |
Sanofi Sa |
Composés aromatiques aminés, procédé pour leur obtention et compositions pharmaceutiques les contenant.
|
|
IL113196A0
(en)
|
1994-03-31 |
1995-06-29 |
Bristol Myers Squibb Co |
Imidazole derivatives and pharmaceutical compositions containing the same
|
|
US5523430A
(en)
|
1994-04-14 |
1996-06-04 |
Bristol-Myers Squibb Company |
Protein farnesyl transferase inhibitors
|
|
US5610145A
(en)
|
1994-04-15 |
1997-03-11 |
Warner-Lambert Company |
Tachykinin antagonists
|
|
IL113472A0
(en)
|
1994-04-29 |
1995-07-31 |
Lilly Co Eli |
Non-peptidyl tachykinin receptor antogonists
|
|
JPH10500944A
(ja)
|
1994-05-05 |
1998-01-27 |
メルク シヤープ エンド ドーム リミテツド |
モルホリン誘導体及びタキキニンのアンタゴニストとしてのそれらの使用
|
|
NZ285750A
(en)
|
1994-05-07 |
1998-08-26 |
Boehringer Ingelheim Int |
Neurokinin (tachykinin) antagonists
|
|
US5510510A
(en)
|
1994-05-10 |
1996-04-23 |
Bristol-Meyers Squibb Company |
Inhibitors of farnesyl protein transferase
|
|
US5563255A
(en)
|
1994-05-31 |
1996-10-08 |
Isis Pharmaceuticals, Inc. |
Antisense oligonucleotide modulation of raf gene expression
|
|
EE03445B1
(et)
|
1994-06-06 |
2001-06-15 |
Warner-Lambert Company |
Tahükiniini (NK1) retseptori antagonistid
|
|
EP0686629A3
(en)
|
1994-06-10 |
1999-02-10 |
Eli Lilly And Company |
Cyclohexyl tachykinine receptor antagonists
|
|
CZ361996A3
(en)
|
1994-06-10 |
1997-04-16 |
Rhone Poulenc Rorer Sa |
Inhibitors of farnesyl-transferase, process of their preparation and pharmaceutical compositions containing thereof
|
|
US5571792A
(en)
|
1994-06-30 |
1996-11-05 |
Warner-Lambert Company |
Histidine and homohistidine derivatives as inhibitors of protein farnesyltransferase
|
|
HUT77948A
(hu)
|
1994-07-12 |
1998-12-28 |
Eli Lilly And Co., |
Heterociklusos tachikinin-receptor antagonisták
|
|
CA2154116A1
(en)
|
1994-07-22 |
1996-01-23 |
Philip Arthur Hipskind |
1-aryl-2-acetamidopentanone derivatives for use as tachykinin receptor antagonists
|
|
GB9415996D0
(en)
|
1994-08-08 |
1994-09-28 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB9415997D0
(en)
|
1994-08-08 |
1994-09-28 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
TW432061B
(en)
|
1994-08-09 |
2001-05-01 |
Pfizer Res & Dev |
Lactams
|
|
WO1996005529A1
(en)
|
1994-08-09 |
1996-02-22 |
Micron Optics, Inc. |
Temperature compensated fiber fabry-perot filters
|
|
CA2155448A1
(en)
|
1994-08-11 |
1996-02-12 |
Katerina Leftheris |
Inhibitors of farnesyl protein transferase
|
|
ATE188464T1
(de)
|
1994-08-11 |
2000-01-15 |
Banyu Pharma Co Ltd |
Substituierte amidderivate
|
|
WO1996005306A2
(en)
|
1994-08-12 |
1996-02-22 |
Myriad Genetics, Inc. |
IN VIVO MUTATIONS AND POLYMORPHISMS IN THE 17q-LINKED BREAST AND OVARIAN CANCER SUSCEPTIBILITY GENE
|
|
AU691958B2
(en)
|
1994-08-12 |
1998-05-28 |
Myriad Genetics, Inc. |
17q-linked breast and ovarian cancer susceptibility gene
|
|
WO1996005169A1
(en)
|
1994-08-12 |
1996-02-22 |
Banyu Pharmaceutical Co., Ltd. |
N,n-disubstituted amic acid derivative
|
|
DK0777659T3
(da)
|
1994-08-15 |
2001-09-03 |
Merck Sharp & Dohme |
Morpholinderivater og deres anvendelse som terapeutiske midler
|
|
DE4429506B4
(de)
|
1994-08-19 |
2007-09-13 |
Degussa Gmbh |
Verfahren zur Extraktion natürlicher Carotinoid-Farbstoffe
|
|
DE4429653C2
(de)
|
1994-08-20 |
1997-04-03 |
Anton Dr More |
Konverter und Verfahren zum Frischen von Metallschmelzen insbesondere von Roheisen zu Stahl
|
|
KR100362620B1
(ko)
|
1994-08-25 |
2003-02-14 |
메렐 파마슈티칼스 인크. |
알레르기성질환치료에유용한치환된피페리딘,이를포함하는약제학적조성물및이의제조방법
|
|
ES2107118T3
(es)
|
1994-08-29 |
1997-11-16 |
Akzo Nobel Nv |
Procedimiento para la preparacion de diesteres cuaternarios.
|
|
GB9417956D0
(en)
|
1994-09-02 |
1994-10-26 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB9418545D0
(en)
|
1994-09-15 |
1994-11-02 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
US5457107A
(en)
|
1994-09-16 |
1995-10-10 |
Merck & Co., Inc. |
Polymorphic form of a tachykinin receptor antagonist
|
|
WO1996010562A1
(en)
|
1994-09-30 |
1996-04-11 |
Novartis Ag |
1-acyl-4-aliphatylaminopiperidine compounds
|
|
TW397825B
(en)
|
1994-10-14 |
2000-07-11 |
Novartis Ag |
Aroyl-piperidine derivatives
|
|
FR2725986B1
(fr)
|
1994-10-21 |
1996-11-29 |
Adir |
Nouveaux derives de piperidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
|
DE69534213T2
(de)
|
1994-10-25 |
2006-01-12 |
Astrazeneca Ab |
Therapeutisch wirksame Heterocyclen
|
|
GB9421709D0
(en)
|
1994-10-27 |
1994-12-14 |
Zeneca Ltd |
Therapeutic compounds
|
|
EP0714891A1
(en)
|
1994-11-22 |
1996-06-05 |
Eli Lilly And Company |
Heterocyclic tachykinin receptor antagonists
|
|
JP4319251B2
(ja)
|
1994-11-22 |
2009-08-26 |
エヌエックスピー ビー ヴィ |
半導体素子を有し導体トラックが形成されている基板が接着層により結合されている支持本体を有する半導体装置
|
|
FR2727411B1
(fr)
|
1994-11-30 |
1997-01-03 |
Rhone Poulenc Rorer Sa |
Nouveaux derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent
|
|
AU3971295A
(en)
|
1994-12-09 |
1996-06-26 |
Warner-Lambert Company |
Substituted tetra- and pentapeptide inhibitors of protein:farnesyl transferase
|
|
PE38997A1
(es)
|
1994-12-13 |
1997-10-02 |
Novartis Ag |
Antagonista de taquicinina
|
|
US5589483A
(en)
|
1994-12-21 |
1996-12-31 |
Geron Corporation |
Isoquinoline poly (ADP-ribose) polymerase inhibitors to treat skin diseases associated with cellular senescence
|
|
GB9426103D0
(en)
|
1994-12-23 |
1995-02-22 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
WO1996021701A2
(en)
|
1995-01-09 |
1996-07-18 |
Magla International Ltd. |
Wear resistant image printing on latex surfaces
|
|
AU4437896A
(en)
|
1995-01-12 |
1996-07-31 |
Glaxo Group Limited |
Piperidine derivatives having tachykinin antagonist activity
|
|
AU4915796A
(en)
|
1995-01-12 |
1996-07-31 |
University Of Pittsburgh |
Inhibitors of prenyl transferases
|
|
FR2729390A1
(fr)
|
1995-01-18 |
1996-07-19 |
Rhone Poulenc Rorer Sa |
Nouveaux inhibiteurs de farnesyl transferase, leur preparation et les compositions pharmaceutiques qui les contiennent
|
|
FR2729951B1
(fr)
|
1995-01-30 |
1997-04-18 |
Sanofi Sa |
Nouveaux composes heterocycliques, procede pour leur preparation et compositions pharmaceutiques en contenant
|
|
FR2730492B1
(fr)
|
1995-02-09 |
1997-03-14 |
Rhone Poulenc Rorer Sa |
Nouveaux inhibiteurs de farnesyl transferase, leur preparation et les compositions pharmaceutiques qui les contiennent
|
|
FR2730491B1
(fr)
|
1995-02-09 |
1997-03-14 |
Rhone Poulenc Rorer Sa |
Nouveaux inhibiteurs de farnesyl transferase, leur preparation et les compositions pharmaceutiques qui les contiennent
|
|
US5633272A
(en)
|
1995-02-13 |
1997-05-27 |
Talley; John J. |
Substituted isoxazoles for the treatment of inflammation
|
|
GB9505492D0
(en)
|
1995-03-18 |
1995-05-03 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB9505491D0
(en)
|
1995-03-18 |
1995-05-03 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
US5554641A
(en)
|
1995-03-20 |
1996-09-10 |
Horwell; David C. |
Nonpeptides as tachykinin antagonists
|
|
GB9505692D0
(en)
|
1995-03-21 |
1995-05-10 |
Glaxo Group Ltd |
Chemical compounds
|
|
NO309272B1
(no)
|
1995-03-24 |
2001-01-08 |
Takeda Chemical Industries Ltd |
Cykliske forbindelser, preparater inneholdende forbindelsene samt mellomprodukter for fremstilling av forbindelsene
|
|
US5684013A
(en)
|
1995-03-24 |
1997-11-04 |
Schering Corporation |
Tricyclic compounds useful for inhibition of g-protein function and for treatment of proliferative diseases
|
|
US5700806A
(en)
|
1995-03-24 |
1997-12-23 |
Schering Corporation |
Tricyclic amide and urea compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
|
|
IL117580A0
(en)
|
1995-03-29 |
1996-07-23 |
Merck & Co Inc |
Inhibitors of farnesyl-protein transferase and pharmaceutical compositions containing them
|
|
US5565568A
(en)
|
1995-04-06 |
1996-10-15 |
Eli Lilly And Company |
2-acylaminopropanamides as tachykinin receptor antagonists
|
|
AU5432696A
(en)
|
1995-04-07 |
1996-10-23 |
Pharmacopeia, Inc. |
Carbonyl-piperazinyl and piperidinil compounds which inhibit farnesyl protein transferase
|
|
US5712280A
(en)
|
1995-04-07 |
1998-01-27 |
Schering Corporation |
Tricyclic compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
|
|
US5891872A
(en)
|
1995-04-07 |
1999-04-06 |
Schering Corporation |
Tricyclic compounds
|
|
IL117798A
(en)
|
1995-04-07 |
2001-11-25 |
Schering Plough Corp |
Tricyclic compounds useful for inhibiting the function of protein - G and for the treatment of malignant diseases, and pharmaceutical preparations containing them
|
|
HUP9802036A3
(en)
|
1995-04-13 |
1999-06-28 |
Aventis Pharmaceuticals Inc Br |
Novel substituted piperazine derivatives having tachykinin receptor antagonists activity, process for producing them an pharmaceutical compositions containing them
|
|
US5831115A
(en)
|
1995-04-21 |
1998-11-03 |
Abbott Laboratories |
Inhibitors of squalene synthase and protein farnesyltransferase
|
|
IL118101A0
(en)
|
1995-05-03 |
1996-09-12 |
Abbott Lab |
Inhibitors of farnesyltransferase
|
|
AU706021B2
(en)
|
1995-05-25 |
1999-06-03 |
Fujisawa Pharmaceutical Co., Ltd. |
Piperazine derivatives
|
|
US5919780A
(en)
|
1995-06-16 |
1999-07-06 |
Warner Lambert Company |
Tricyclic inhibitors of protein farnesyltransferase
|
|
GB9513118D0
(en)
|
1995-06-28 |
1995-08-30 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB9513117D0
(en)
|
1995-06-28 |
1995-08-30 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB9513121D0
(en)
|
1995-06-28 |
1995-08-30 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
ATE199552T1
(de)
|
1995-07-07 |
2001-03-15 |
Pfizer |
Substituierte benzolaktamverbindungen als substanz-p-antagonisten
|
|
FR2736641B1
(fr)
|
1995-07-10 |
1997-08-22 |
Rhone Poulenc Rorer Sa |
Nouveaux inhibiteurs de farnesyl transferase, leur preparation et les compositions pharmaceutiques qui les contiennent
|
|
AT402617B
(de)
|
1995-07-11 |
1997-07-25 |
Datacon Schweitzer & Zeindl Gm |
Anlage zum automatisierten, hermetischen anlage zum automatisierten, hermetischen verschliessen von gehäusen verschliessen von gehäusen
|
|
FR2736638B1
(fr)
|
1995-07-12 |
1997-08-22 |
Rhone Poulenc Rorer Sa |
Nouveaux inhibiteurs de farnesyl transferase, leur preparation et les compositions pharmaceutiques qui les contiennent
|
|
CH690163A5
(fr)
|
1995-07-28 |
2000-05-31 |
Symphar Sa |
Dérivés gem-diphosphonates substitués utiles en tant qu'agents anti-cancers.
|
|
IL123147A
(en)
|
1995-08-02 |
2004-02-19 |
Univ Newcastle Ventures Ltd |
Benzamide imidazole - 4 carboxamide and their use
|
|
TW340842B
(en)
|
1995-08-24 |
1998-09-21 |
Pfizer |
Substituted benzylaminopiperidine compounds
|
|
US6020343A
(en)
|
1995-10-13 |
2000-02-01 |
Merck Frosst Canada, Inc. |
(Methylsulfonyl)phenyl-2-(5H)-furanones as COX-2 inhibitors
|
|
EP0858444A4
(en)
|
1995-10-18 |
1999-12-01 |
Merck & Co Inc |
Cyclopentyl tachykinin receptor antagonists
|
|
CA2235986C
(en)
|
1995-11-06 |
2006-09-12 |
University Of Pittsburgh |
Inhibitors of protein isoprenyl transferases
|
|
DE19541283A1
(de)
|
1995-11-06 |
1997-05-07 |
Boehringer Ingelheim Kg |
Neue Aminosäurederivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen
|
|
GB9523244D0
(en)
|
1995-11-14 |
1996-01-17 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
ES2206607T3
(es)
|
1995-11-17 |
2004-05-16 |
Gesellschaft Fur Biotechnologische Forschung Mbh (Gbf) |
Derivados de epotilones, preparacion y utilizacion.
|
|
EP0862435A4
(en)
|
1995-11-22 |
1999-02-03 |
Merck & Co Inc |
Inhibitors of farnesyl-protein transferase
|
|
US6060469A
(en)
|
1995-11-23 |
2000-05-09 |
Merck Sharp & Dohme Ltd. |
Spiro-piperidine derivatives and their use as tachykinin antagonists
|
|
GB9524157D0
(en)
|
1995-11-25 |
1996-01-24 |
Pfizer Ltd |
Therapeutic agents
|
|
RU2135494C1
(ru)
|
1995-12-01 |
1999-08-27 |
Санкио Компани Лимитед |
Гетероциклические соединения и композиция на их основе, проявляющая антагонистическое действие в отношении рецепторов тахикинина
|
|
EA000710B1
(ru)
|
1995-12-08 |
2000-02-28 |
Жансен Фармасетика Н.В. |
(имидазол-5-ил)метил-2-хинолиноновые производные, ингибирующие фарнезилпротеин-трансферазу
|
|
GB9525296D0
(en)
|
1995-12-11 |
1996-02-07 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
IL125062A
(en)
|
1995-12-22 |
2003-11-23 |
Schering Corp |
Tricyclic amides and pharmaceutical compositions containing them for inhibition of g-protein function and for treatment of proliferative diseases
|
|
US6008372A
(en)
|
1996-01-16 |
1999-12-28 |
Warner-Lambert Company |
Substituted dinaphthylmethyl and diheteroarylmethylacetyl histidine inhibitors of protein farnesyltransferase
|
|
US6673927B2
(en)
|
1996-02-16 |
2004-01-06 |
Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. |
Farnesyl transferase inhibitors
|
|
WO1997038665A2
(en)
|
1996-04-03 |
1997-10-23 |
Merck & Co., Inc. |
Inhibitors of farnesyl-protein transferase
|
|
SI22713B
(sl)
|
1996-04-12 |
2009-12-31 |
Searle & Co |
Substituirani benzensulfonamidni derivati kot predzdravila COX-2 inhibitorjev
|
|
IL126833A0
(en)
|
1996-05-22 |
1999-08-17 |
Warner Lambert Co |
Inhibitors of protein farnesyl transferase
|
|
CA2260216A1
(en)
|
1996-07-15 |
1998-01-22 |
Bristol-Myers Squibb Company |
Thiadioxobenzodiazepine inhibitors of farnesyl protein transferase
|
|
US5861419A
(en)
|
1996-07-18 |
1999-01-19 |
Merck Frosst Canad, Inc. |
Substituted pyridines as selective cyclooxygenase-2 inhibitors
|
|
EP1611885A1
(en)
|
1996-07-26 |
2006-01-04 |
Susan P. Perrine |
Use of an inducing agent for the treatment of blood, viral and cellular disorders
|
|
WO1999001124A1
(en)
|
1996-12-03 |
1999-01-14 |
Sloan-Kettering Institute For Cancer Research |
Synthesis of epothilones, intermediates thereto, analogues and uses thereof
|
|
CA2276150A1
(en)
|
1996-12-30 |
1998-07-09 |
Steven D. Young |
Inhibitors of farnesyl-protein transferase
|
|
JP2002511054A
(ja)
|
1996-12-30 |
2002-04-09 |
メルク エンド カンパニー インコーポレーテッド |
ファルネシル蛋白トランスフェラーゼ阻害薬
|
|
JP2002515488A
(ja)
|
1998-05-15 |
2002-05-28 |
ギルフォード ファーマシューティカルズ インコーポレイテッド |
カルボキサミド化合物、組成物、及びｐａｒｐ活性の抑制方法
|
|
EP1124805B1
(de)
|
1998-10-30 |
2003-05-21 |
Lonza AG |
Verfahren zur herstellung von 4-[(2',5'-diamino-6'-halogenpyrimidin-4'-yl)amino]-cyclopent-2-enylmethanolen
|
|
CN1331682A
(zh)
|
1998-11-03 |
2002-01-16 |
巴斯福股份公司 |
取代的2－苯基苯并咪唑类,其制备和用途
|
|
HRP20010451A2
(en)
|
1998-11-17 |
2003-04-30 |
Basf Ag |
2-phenylbenzimidazoles and 2-phenylindoles, and production and use thereof
|
|
IL143303A0
(en)
|
1998-11-27 |
2002-04-21 |
Basf Ag |
Substituted benzimidazoles and their use as parp inhibitors
|
|
JP2002536968A
(ja)
|
1999-01-29 |
2002-11-05 |
イムクローン システムズ インコーポレイティド |
Ｋｄｒに特異的な抗体およびその使用
|
|
GB9904387D0
(en)
|
1999-02-25 |
1999-04-21 |
Pharmacia & Upjohn Spa |
Antitumour synergistic composition
|
|
EP1187633A4
(en)
|
1999-04-08 |
2005-05-11 |
Arch Dev Corp |
USE OF ANTI-VEGF ANTIBODIES TO ENHANCE RADIATION IN ANTICANCER THERAPY
|
|
DE19918211A1
(de)
|
1999-04-22 |
2000-10-26 |
Basf Ag |
Cycloalkylsubstituierte Benzimidazole, deren Herstellung und Anwendung
|
|
DE19920936A1
(de)
|
1999-05-07 |
2000-11-09 |
Basf Ag |
Heterozyklisch substituierte Benzimidazole, deren Herstellung und Anwendung
|
|
AU7314200A
(en)
|
1999-09-17 |
2001-04-24 |
Yamanouchi Pharmaceutical Co., Ltd. |
Benzimidazole derivatives
|
|
DE60028227T2
(de)
|
1999-10-27 |
2007-03-29 |
Cytokinetics, Inc., South San Francisco |
Chinazolinone benutzende verfahren und zusammenstellungen
|
|
US6545004B1
(en)
|
1999-10-27 |
2003-04-08 |
Cytokinetics, Inc. |
Methods and compositions utilizing quinazolinones
|
|
ATE372337T1
(de)
|
2000-02-01 |
2007-09-15 |
Abbott Gmbh & Co Kg |
Heterozyklische verbindungen und deren anwendung als parp-inhibitoren
|
|
DE10022925A1
(de)
|
2000-05-11 |
2001-11-15 |
Basf Ag |
Substituierte Indole als PARP-Inhibitoren
|
|
EP1351671A1
(en)
|
2001-01-19 |
2003-10-15 |
Cytokinetics, Inc. |
Triphenylmethane kinesin inhibitors
|
|
EP1360180A1
(en)
|
2001-01-19 |
2003-11-12 |
Cytokinetics, Inc. |
Phenothiazine kinesin inhibitors
|
|
JPWO2002068407A1
(ja)
|
2001-02-28 |
2004-06-24 |
山之内製薬株式会社 |
ベンゾイミダゾール化合物
|
|
AU2002252614B2
(en)
|
2001-04-10 |
2006-09-14 |
Merck Sharp & Dohme Corp. |
Inhibitors of Akt activity
|
|
WO2002083140A1
(en)
|
2001-04-10 |
2002-10-24 |
Merck & Co., Inc. |
Inhibitors of akt activity
|
|
AU2002251266A1
(en)
|
2001-04-10 |
2002-10-28 |
Merck Sharp And Dohme Limited |
Inhibitors of akt activity
|
|
WO2002083139A1
(en)
|
2001-04-10 |
2002-10-24 |
Merck & Co., Inc. |
Inhibitors of akt activity
|
|
WO2003007959A1
(en)
|
2001-07-16 |
2003-01-30 |
Fujisawa Pharmaceutical Co., Ltd. |
Quinoxaline derivatives which have parp inhibitory action
|
|
WO2003013526A1
(en)
|
2001-08-08 |
2003-02-20 |
Merck & Co. Inc. |
Anticoagulant compounds
|
|
WO2003039460A2
(en)
|
2001-11-07 |
2003-05-15 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
|
DE60222302T2
(de)
|
2001-12-06 |
2008-05-29 |
Merck & Co., Inc. |
Inhibitoren von mitotischem kinesin
|
|
WO2003049527A2
(en)
|
2001-12-06 |
2003-06-19 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
|
US7244723B2
(en)
|
2001-12-06 |
2007-07-17 |
Merck & Co., Inc. |
Substituted furopyrimidinones as a mitotic kinesin inhibitors
|
|
EP1481077B1
(en)
|
2001-12-06 |
2009-11-04 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
|
EP1551812B1
(en)
|
2001-12-06 |
2009-03-04 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
|
ATE357460T1
(de)
|
2002-01-18 |
2007-04-15 |
Pf Medicament |
Antikörper gegen igf-ir und ihre verwendungen
|
|
JPWO2003062234A1
(ja)
|
2002-01-23 |
2005-05-19 |
山之内製薬株式会社 |
キノキサリン化合物
|
|
AU2003249597B2
(en)
|
2002-03-08 |
2007-06-28 |
Merck Sharp & Dohme Corp. |
Mitotic kinesin inhibitors
|
|
CA2481229C
(en)
|
2002-04-08 |
2010-09-21 |
Merck & Co., Inc. |
Substituted pyrazine inhibitors of akt
|
|
WO2003086394A1
(en)
|
2002-04-08 |
2003-10-23 |
Merck & Co., Inc. |
Inhibitors of akt activity
|
|
AU2003226271B2
(en)
|
2002-04-08 |
2007-10-18 |
Merck Sharp & Dohme Corp. |
Fused quinoxaline derivatives as inhibitors of Akt activity
|
|
JP4451136B2
(ja)
|
2002-04-08 |
2010-04-14 |
メルク エンド カムパニー インコーポレーテッド |
Ａｋｔ活性阻害薬
|
|
CA2485343A1
(en)
|
2002-05-23 |
2004-05-13 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
|
EP1509507A4
(en)
|
2002-05-23 |
2006-09-13 |
Merck & Co Inc |
INHIBITORS OF MITOTIC KINESINE
|
|
US20040034078A1
(en)
|
2002-06-14 |
2004-02-19 |
Agouron Pharmaceuticals, Inc. |
Benzimidazole inhibitors of poly(ADP-ribosyl) polymerase
|
|
PL374190A1
(en)
|
2002-06-14 |
2005-10-03 |
Merck & Co, Inc. |
Mitotic kinesin inhibitors
|
|
EP1515949B1
(en)
|
2002-06-14 |
2007-03-14 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
|
WO2004014861A1
(ja)
|
2002-08-09 |
2004-02-19 |
Kyorin Pharmaceutical Co., Ltd. |
4-置換キノリン-8-カルボン酸アミド誘導体とその薬理上許容される付加塩
|
|
CA2500848A1
(en)
|
2002-10-18 |
2004-05-06 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
|
CA2509212A1
(en)
|
2002-12-20 |
2004-07-15 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
|
WO2004058700A2
(en)
|
2002-12-20 |
2004-07-15 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
|
EP1585726A1
(en)
*
|
2003-01-06 |
2005-10-19 |
Eli Lilly And Company |
Fused heterocyclic derivatives as ppar modulators
|
|
WO2004087050A2
(en)
|
2003-03-28 |
2004-10-14 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
|
HU0301154D0
(en)
|
2003-04-28 |
2003-07-28 |
Hideg Kalman Dr |
Pharmaceutical composition
|
|
JP2007520471A
(ja)
|
2003-12-22 |
2007-07-26 |
イーライ リリー アンド カンパニー |
Ｐｐａｒ受容体調節物質としての二環式誘導体
|
|
MXPA06009701A
(es)
|
2004-02-26 |
2007-03-26 |
Inotek Pharmaceuticals Corp |
Derivados de isoquinolina y metodos de uso de los mismos.
|
|
EA012837B1
(ru)
*
|
2004-06-30 |
2009-12-30 |
Янссен Фармацевтика Н.В. |
Производные хиназолинона в качестве ингибиторов parp
|
|
WO2006021801A1
(en)
|
2004-08-26 |
2006-03-02 |
Kudos Pharmaceuticals Limited |
4-heteroarylmethyl substituted phthalazinone derivatives
|
|
KR100876520B1
(ko)
|
2004-09-22 |
2008-12-31 |
화이자 인코포레이티드 |
폴리(ａｄｐ-리보오스) 폴리머라제 억제제의 제조 방법
|
|
WO2006110683A1
(en)
|
2005-04-11 |
2006-10-19 |
Abbott Laboratories |
2-substituted-1h-benzimidazole-4-carboxamides are parp inhibitors
|
|
TWI375673B
(en)
|
2005-04-11 |
2012-11-01 |
Abbott Lab |
1h-benzimidazole-4-carboxamides substituted with a quaternary carbon at the 2-position are potent parp inhibitors
|
|
CN101316834A
(zh)
*
|
2005-09-29 |
2008-12-03 |
艾博特公司 |
在2位取代有苯基的1h-苯并咪唑-4-甲酰胺是强效parp抑制剂
|
|
US7462724B2
(en)
|
2005-11-15 |
2008-12-09 |
Abbott Laboratories |
Substituted 1H-benzimidazole-4-carboxamides are potent PARP inhibitors
|
|
AU2007232297B2
(en)
*
|
2006-04-03 |
2012-09-20 |
Msd Italia S.R.L. |
Amide substituted indazole and benzotriazole derivatives as poly(ADP-ribose)polymerase (PARP) inhibitors
|
|
CN101511821B
(zh)
|
2006-05-02 |
2013-07-17 |
Abbvie公司 |
取代的1h-苯并咪唑-4-羧酰胺类化合物是有效的parp抑制剂
|
|
US20090062268A1
(en)
*
|
2007-08-27 |
2009-03-05 |
Lead Therapeutics, Inc. |
Novel inhibitors of poly(adp-ribose)polymerase (parp)
|
|
EP2247600A4
(en)
*
|
2008-02-06 |
2011-09-14 |
Biomarin Pharm Inc |
INHIBITORS BASED ON BENZOXAZOLE-CARBOXAMIDE COMPOUNDS OF POLY (ADP-RIBOSE) POLYMERASE (PARP) ACTIVITY
|