MXPA04002836A - Derivados de alquilaminopiridazinona sustituidos, procedimiento para la preparacion de los mismos y composiciones farmaceuticas que los contienen. - Google Patents
Derivados de alquilaminopiridazinona sustituidos, procedimiento para la preparacion de los mismos y composiciones farmaceuticas que los contienen.Info
- Publication number
- MXPA04002836A MXPA04002836A MXPA04002836A MXPA04002836A MXPA04002836A MX PA04002836 A MXPA04002836 A MX PA04002836A MX PA04002836 A MXPA04002836 A MX PA04002836A MX PA04002836 A MXPA04002836 A MX PA04002836A MX PA04002836 A MXPA04002836 A MX PA04002836A
- Authority
- MX
- Mexico
- Prior art keywords
- general formula
- pyridazin
- hydrogen
- dioxin
- piperazin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/22—Nitrogen and oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU0103912A HU227237B1 (en) | 2001-09-27 | 2001-09-27 | Substituted alkylpyridazinone derivatives, process for their preparation, pharmaceutical compositions containing them |
| PCT/HU2002/000096 WO2003027097A1 (en) | 2001-09-27 | 2002-09-26 | Substituted alkylaminopyridazinone derivatives, process for the preparation thereof and pharmaceutical composition containing the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA04002836A true MXPA04002836A (es) | 2004-07-05 |
Family
ID=89979721
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA04002836A MXPA04002836A (es) | 2001-09-27 | 2002-09-26 | Derivados de alquilaminopiridazinona sustituidos, procedimiento para la preparacion de los mismos y composiciones farmaceuticas que los contienen. |
| MXPA04002838A MXPA04002838A (es) | 2001-09-27 | 2002-09-26 | Derivados de alquilaminopiridazinona sustituidos, procedimiento para la preparacion de los mismos y composiciones farmaceuticas que los contienen. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA04002838A MXPA04002838A (es) | 2001-09-27 | 2002-09-26 | Derivados de alquilaminopiridazinona sustituidos, procedimiento para la preparacion de los mismos y composiciones farmaceuticas que los contienen. |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US20050043314A1 (enExample) |
| EP (2) | EP1430034B1 (enExample) |
| JP (2) | JP4472337B2 (enExample) |
| KR (2) | KR100911069B1 (enExample) |
| CN (3) | CN1325489C (enExample) |
| AT (2) | ATE288910T1 (enExample) |
| AU (2) | AU2002330656B9 (enExample) |
| BR (2) | BR0212932A (enExample) |
| CA (2) | CA2461467A1 (enExample) |
| CZ (2) | CZ2004528A3 (enExample) |
| DE (2) | DE60202969T2 (enExample) |
| DK (2) | DK1430034T3 (enExample) |
| EA (2) | EA006942B1 (enExample) |
| ES (2) | ES2237696T3 (enExample) |
| HU (1) | HU227237B1 (enExample) |
| MA (2) | MA27137A1 (enExample) |
| MX (2) | MXPA04002836A (enExample) |
| NO (2) | NO326370B1 (enExample) |
| NZ (2) | NZ532104A (enExample) |
| PL (2) | PL369256A1 (enExample) |
| PT (2) | PT1430047E (enExample) |
| SI (2) | SI1430034T1 (enExample) |
| SK (2) | SK1892004A3 (enExample) |
| WO (2) | WO2003027078A1 (enExample) |
| ZA (2) | ZA200402545B (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7504395B2 (en) * | 2001-07-20 | 2009-03-17 | Psychogenics, Inc. | Treatment for attention-deficit hyperactivity disorder |
| HU227592B1 (en) * | 2002-11-13 | 2011-09-28 | Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag | Use of substituted alkyl-piridazinone derivatives for the treatment of memory decline and learning malfunctions |
| JP5147866B2 (ja) * | 2007-03-15 | 2013-02-20 | メルク・シャープ・アンド・ドーム・コーポレーション | グルカン合成酵素阻害剤として有用であるピリダジノン誘導体 |
| BR112020022006A2 (pt) * | 2018-04-30 | 2021-01-26 | Ribon Therapeutics Inc. | piridazinonas como inibidores de parp7 |
| CN109053693B (zh) | 2018-09-20 | 2021-02-05 | 顺毅股份有限公司 | 哒嗪胺类化合物的制备及其应用 |
| WO2020223229A1 (en) | 2019-04-29 | 2020-11-05 | Ribon Therapeutics, Inc. | Solid forms of a parp7 inhibitor |
| TWI902715B (zh) | 2019-10-30 | 2025-11-01 | 美商律幫治療股份有限公司 | 作為ｐａｒｐ７抑制劑的嗒酮 |
| WO2022188889A1 (zh) * | 2021-03-12 | 2022-09-15 | 杭州英创医药科技有限公司 | 作为parp7抑制剂的化合物 |
| CN115490671B (zh) * | 2022-10-21 | 2024-05-14 | 水木未来(北京)科技有限公司 | Parp7抑制剂及其制备方法 |
| CN118388414A (zh) * | 2023-01-17 | 2024-07-26 | 中国药科大学 | 哒嗪酮类化合物及其制备方法、药物组合物和应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH557820A (de) * | 1970-11-12 | 1975-01-15 | Sandoz Ag | Verfahren zur herstellung von neuen 2-(2-hydroxyalkyl)4,5-dihydro-pyridazin (2h)-3-onen. |
| IE62890B1 (en) * | 1988-12-06 | 1995-03-08 | Hafslund Nycomed Pharma | New piperazinylalkyl-3(2h)-pyridazinones process for the preparation thereof and the use thereof as agents lowering blood pressure |
| PL164079B1 (pl) | 1990-06-15 | 1994-06-30 | Akad Medyczna | posób wytwarzania nowych 2-amlnoalkilopochodnych 5-aminometyleno-6-/p-chlorofenylo /-4,5-dihydro-2H- plrydazyn -3-onu |
| HU209388B (en) * | 1990-12-27 | 1994-05-30 | Richter Gedeon Vegyeszet | Process for producing new 3/2h/-pyridazinones and pharmaceutical compositions comprising same |
| HU214320B (hu) | 1991-12-20 | 1998-03-02 | EGIS Gyógyszergyár Rt. | Eljárás új 3(2H)-piridazinon-származékok és ezeket tartalmazó gyógyszerkészítmények előállítására |
| HU224067B1 (hu) | 1995-05-29 | 2005-05-30 | Gyógyszerkutató Intézet Kft. | 3(2H)-Piridazinon-származékok és e vegyületeket tartalmazó gyógyszerkészítmények |
| JP2004500314A (ja) | 1998-06-05 | 2004-01-08 | エギシュ ヂョヂセルヂャール エルテー | ３（２ｈ）−ピリダジノン−４−置換アミノ−５−クロロ−誘導体の製法 |
-
2001
- 2001-09-27 HU HU0103912A patent/HU227237B1/hu not_active IP Right Cessation
-
2002
- 2002-09-26 EP EP02767729A patent/EP1430034B1/en not_active Expired - Lifetime
- 2002-09-26 WO PCT/HU2002/000097 patent/WO2003027078A1/en not_active Ceased
- 2002-09-26 US US10/490,959 patent/US20050043314A1/en not_active Abandoned
- 2002-09-26 BR BR0212932-9A patent/BR0212932A/pt not_active IP Right Cessation
- 2002-09-26 EA EA200400470A patent/EA006942B1/ru not_active IP Right Cessation
- 2002-09-26 DE DE60202969T patent/DE60202969T2/de not_active Expired - Lifetime
- 2002-09-26 EA EA200400469A patent/EA006392B1/ru not_active IP Right Cessation
- 2002-09-26 JP JP2003530685A patent/JP4472337B2/ja not_active Expired - Lifetime
- 2002-09-26 DE DE60202970T patent/DE60202970T2/de not_active Expired - Lifetime
- 2002-09-26 NZ NZ532104A patent/NZ532104A/en unknown
- 2002-09-26 AU AU2002330656A patent/AU2002330656B9/en not_active Ceased
- 2002-09-26 EP EP02762620A patent/EP1430047B1/en not_active Expired - Lifetime
- 2002-09-26 SK SK1892004A patent/SK1892004A3/sk unknown
- 2002-09-26 PL PL02369256A patent/PL369256A1/xx unknown
- 2002-09-26 CA CA002461467A patent/CA2461467A1/en not_active Abandoned
- 2002-09-26 CN CNB028204425A patent/CN1325489C/zh not_active Expired - Fee Related
- 2002-09-26 BR BR0212839-0A patent/BR0212839A/pt not_active IP Right Cessation
- 2002-09-26 US US10/491,151 patent/US6930110B2/en not_active Expired - Fee Related
- 2002-09-26 WO PCT/HU2002/000096 patent/WO2003027097A1/en not_active Ceased
- 2002-09-26 CN CNB028189752A patent/CN100368404C/zh not_active Expired - Fee Related
- 2002-09-26 PT PT02762620T patent/PT1430047E/pt unknown
- 2002-09-26 MX MXPA04002836A patent/MXPA04002836A/es active IP Right Grant
- 2002-09-26 SI SI200230107T patent/SI1430034T1/xx unknown
- 2002-09-26 JP JP2003530669A patent/JP2005508914A/ja active Pending
- 2002-09-26 MX MXPA04002838A patent/MXPA04002838A/es active IP Right Grant
- 2002-09-26 CZ CZ2004528A patent/CZ2004528A3/cs unknown
- 2002-09-26 PT PT02767729T patent/PT1430034E/pt unknown
- 2002-09-26 DK DK02767729T patent/DK1430034T3/da active
- 2002-09-26 AU AU2002328166A patent/AU2002328166B2/en not_active Ceased
- 2002-09-26 ES ES02767729T patent/ES2237696T3/es not_active Expired - Lifetime
- 2002-09-26 AT AT02762620T patent/ATE288910T1/de not_active IP Right Cessation
- 2002-09-26 CN CN200710104934XA patent/CN101099740B/zh not_active Expired - Fee Related
- 2002-09-26 CZ CZ2004532A patent/CZ2004532A3/cs unknown
- 2002-09-26 SK SK1902004A patent/SK1902004A3/sk unknown
- 2002-09-26 CA CA002461510A patent/CA2461510C/en not_active Expired - Fee Related
- 2002-09-26 NZ NZ532103A patent/NZ532103A/en unknown
- 2002-09-26 PL PL02369107A patent/PL369107A1/xx not_active IP Right Cessation
- 2002-09-26 ES ES02762620T patent/ES2237690T3/es not_active Expired - Lifetime
- 2002-09-26 DK DK02762620T patent/DK1430047T3/da active
- 2002-09-26 SI SI200230109T patent/SI1430047T1/xx unknown
- 2002-09-26 AT AT02767729T patent/ATE288899T1/de not_active IP Right Cessation
- 2002-09-26 KR KR1020047004607A patent/KR100911069B1/ko not_active Expired - Fee Related
- 2002-09-26 KR KR1020047004606A patent/KR100890667B1/ko not_active Expired - Fee Related
-
2004
- 2004-03-24 MA MA27588A patent/MA27137A1/fr unknown
- 2004-03-24 MA MA27589A patent/MA27068A1/fr unknown
- 2004-03-31 ZA ZA200402545A patent/ZA200402545B/en unknown
- 2004-03-31 ZA ZA200402544A patent/ZA200402544B/en unknown
- 2004-04-16 NO NO20041551A patent/NO326370B1/no not_active IP Right Cessation
- 2004-04-26 NO NO20041704A patent/NO325080B1/no not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU2002328166B2 (en) | Substituted alkylaminopyridazinone derivatives, process for the preparation thereof and pharmaceutical composition containing the same | |
| AU2002328166A1 (en) | Substituted alkylaminopyridazinone derivatives, process for the preparation thereof and pharmaceutical composition containing the same | |
| AU2002330656A1 (en) | Substituted alkylaminopyridazinone derivatives, process for the preparation thereof and pharmaceutical composition containing the same | |
| MXPA05005137A (es) | Alquil-piridazinonas sustituidas para el tratamiento de trastornos de la memoria y del aprendizaje. | |
| EA007202B1 (ru) | Новые производные пиперидинилалкиламинопиридазинона, способ их получения и содержащие их фармацевтические композиции | |
| HK1069817B (en) | Substituted alkylaminopyridazinone derivatives, process for the preparation thereof and pharmaceutical composition containing the same | |
| HK1069816B (en) | Substituted alkylaminopyridazinone derivatives, process for the preparation thereof and pharmaceutical composition containing the same | |
| HU227294B1 (en) | Substituted alkylpyridazone derivatives, process for their preparation and pharmaceutical compositions containing them | |
| HK1115728B (en) | Substituted alkylaminopyridazinone derivatives, process for the preparation thereof and pharmaceutical composition containing the same |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |