MX2011012262A - 3-[4-(7h-pirrolo[2,3-d]pirimidin-4-il)-1h-pirazol-1-il] octano-o heptano-nitrilo como inhibidores de cinasas janus (jak). - Google Patents

3-[4-(7h-pirrolo[2,3-d]pirimidin-4-il)-1h-pirazol-1-il] octano-o heptano-nitrilo como inhibidores de cinasas janus (jak).

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Publication number
MX2011012262A
MX2011012262A MX2011012262A MX2011012262A MX2011012262A MX 2011012262 A MX2011012262 A MX 2011012262A MX 2011012262 A MX2011012262 A MX 2011012262A MX 2011012262 A MX2011012262 A MX 2011012262A MX 2011012262 A MX2011012262 A MX 2011012262A
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MX
Mexico
Prior art keywords
salt
compound
patient
pyrrolo
pyrazol
Prior art date
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MX2011012262A
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English (en)
Spanish (es)
Inventor
James D Rodgers
Yun-Long Li
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Incyte Corp
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Application filed by Incyte Corp filed Critical Incyte Corp
Publication of MX2011012262A publication Critical patent/MX2011012262A/es

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/525Isoalloxazines, e.g. riboflavins, vitamin B2
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    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

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MX2011012262A 2009-05-22 2010-05-21 3-[4-(7h-pirrolo[2,3-d]pirimidin-4-il)-1h-pirazol-1-il] octano-o heptano-nitrilo como inhibidores de cinasas janus (jak). MX2011012262A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18058209P 2009-05-22 2009-05-22
PCT/US2010/035728 WO2010135621A1 (en) 2009-05-22 2010-05-21 3-[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl]octane- or heptane-nitrile as jak inhibitors

Publications (1)

Publication Number Publication Date
MX2011012262A true MX2011012262A (es) 2012-01-25

Family

ID=42246359

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011012262A MX2011012262A (es) 2009-05-22 2010-05-21 3-[4-(7h-pirrolo[2,3-d]pirimidin-4-il)-1h-pirazol-1-il] octano-o heptano-nitrilo como inhibidores de cinasas janus (jak).

Country Status (36)

Country Link
US (3) US8604043B2 (OSRAM)
EP (2) EP3643312A1 (OSRAM)
JP (2) JP6172939B2 (OSRAM)
KR (1) KR20120030447A (OSRAM)
CN (2) CN106967070A (OSRAM)
AR (1) AR076920A1 (OSRAM)
AU (1) AU2010249443B2 (OSRAM)
BR (1) BRPI1012108B8 (OSRAM)
CA (1) CA2761954C (OSRAM)
CL (1) CL2011002955A1 (OSRAM)
CO (1) CO6470876A2 (OSRAM)
CR (1) CR20110621A (OSRAM)
CY (1) CY1122425T1 (OSRAM)
DK (1) DK2432472T3 (OSRAM)
EA (1) EA020494B1 (OSRAM)
EC (1) ECSP11011534A (OSRAM)
ES (1) ES2761300T3 (OSRAM)
HR (1) HRP20192203T1 (OSRAM)
HU (1) HUE046493T2 (OSRAM)
IL (1) IL216359A (OSRAM)
LT (1) LT2432472T (OSRAM)
ME (1) ME03556B (OSRAM)
MX (1) MX2011012262A (OSRAM)
MY (1) MY161416A (OSRAM)
NZ (1) NZ596374A (OSRAM)
PE (1) PE20120371A1 (OSRAM)
PL (1) PL2432472T3 (OSRAM)
PT (1) PT2432472T (OSRAM)
RS (1) RS59632B1 (OSRAM)
SG (2) SG176111A1 (OSRAM)
SI (1) SI2432472T1 (OSRAM)
SM (1) SMT201900698T1 (OSRAM)
TW (1) TWI484962B (OSRAM)
UA (1) UA106078C2 (OSRAM)
WO (1) WO2010135621A1 (OSRAM)
ZA (1) ZA201108541B (OSRAM)

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