MD1233C2 - Derivaţi de eritromicină, procedeu de preparare a lor şi compoziţie farmaceutică pe baza acestora - Google Patents

Derivaţi de eritromicină, procedeu de preparare a lor şi compoziţie farmaceutică pe baza acestora Download PDF

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Publication number
MD1233C2
MD1233C2 MD97-0010A MD970010A MD1233C2 MD 1233 C2 MD1233 C2 MD 1233C2 MD 970010 A MD970010 A MD 970010A MD 1233 C2 MD1233 C2 MD 1233C2
Authority
MD
Moldova
Prior art keywords
preparation
base
pharmaceutical composition
erythromycin derivatives
erythromycin
Prior art date
Application number
MD97-0010A
Other languages
English (en)
Russian (ru)
Other versions
MD1233B1 (ro
Inventor
Constantin Agouridas
Jean-Francois Chantot
Alexis Denis
Solange Gouin D'ambrieres
Odile Le Martret
Original Assignee
Roussel Uclaf, Societe Anonyme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf, Societe Anonyme filed Critical Roussel Uclaf, Societe Anonyme
Publication of MD1233B1 publication Critical patent/MD1233B1/ro
Publication of MD1233C2 publication Critical patent/MD1233C2/ro

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Indole Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)

Abstract

Invenţia se referă la derivaţi de eritromicină utilizaţi ca medicamente în lupta cu infecţiile, în particular la antibiotice.Sunt revendicaţi derivaţi de eritromicină cu formula (I),în care R reprezintă un radical -(CH2)nAr, n fiind 3, 4 sau 5,Ar reprezintă un radical heterociclic, eventual substituit,Z reprezintă un atom de hidrogen sau restul unui acid,precum şi un procedeu de preparare şi compoziţie farmaceutică pe baza acestora.
MD97-0010A 1994-05-03 1995-05-02 Derivaţi de eritromicină, procedeu de preparare a lor şi compoziţie farmaceutică pe baza acestora MD1233C2 (ro)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9405368A FR2719587B1 (fr) 1994-05-03 1994-05-03 Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
PCT/FR1995/000565 WO1995029929A1 (fr) 1994-05-03 1995-05-02 Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments

Publications (2)

Publication Number Publication Date
MD1233B1 MD1233B1 (ro) 1999-05-31
MD1233C2 true MD1233C2 (ro) 2000-10-31

Family

ID=9462785

Family Applications (1)

Application Number Title Priority Date Filing Date
MD97-0010A MD1233C2 (ro) 1994-05-03 1995-05-02 Derivaţi de eritromicină, procedeu de preparare a lor şi compoziţie farmaceutică pe baza acestora

Country Status (42)

Country Link
US (2) US5635485A (ro)
EP (1) EP0680967B1 (ro)
JP (4) JP2992540B2 (ro)
KR (1) KR100312267B1 (ro)
CN (2) CN1052984C (ro)
AP (1) AP558A (ro)
AT (1) ATE172203T1 (ro)
AU (1) AU684027B2 (ro)
BG (1) BG63087B1 (ro)
BR (1) BR9507700A (ro)
CA (1) CA2189271C (ro)
CZ (1) CZ293455B6 (ro)
DE (2) DE69505296T2 (ro)
DK (1) DK0680967T3 (ro)
DZ (1) DZ1878A1 (ro)
EE (1) EE03263B1 (ro)
ES (1) ES2122472T3 (ro)
FI (1) FI111263B (ro)
FR (1) FR2719587B1 (ro)
GE (1) GEP19991538B (ro)
HU (2) HU227493B1 (ro)
IL (1) IL113245A (ro)
LU (1) LU90872I2 (ro)
LV (1) LV11739B (ro)
MA (1) MA23534A1 (ro)
MD (1) MD1233C2 (ro)
NL (1) NL300077I1 (ro)
NO (2) NO308853B1 (ro)
NZ (1) NZ285416A (ro)
OA (1) OA10319A (ro)
PL (1) PL182034B1 (ro)
RO (1) RO113350B1 (ro)
RU (1) RU2144036C1 (ro)
SI (1) SI0680967T1 (ro)
SK (1) SK281707B6 (ro)
TJ (1) TJ313B (ro)
TN (1) TNSN95049A1 (ro)
TW (1) TW341573B (ro)
UA (1) UA51618C2 (ro)
WO (1) WO1995029929A1 (ro)
YU (1) YU49235B (ro)
ZA (1) ZA953501B (ro)

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BG63087B1 (bg) 2001-03-30
DZ1878A1 (fr) 2002-02-17
AP558A (en) 1996-11-07
JP2007269810A (ja) 2007-10-18
TNSN95049A1 (fr) 1996-02-06
DE69505296T2 (de) 1999-04-22
CZ321496A3 (en) 1997-08-13
MA23534A1 (fr) 1995-12-31
NO964654D0 (no) 1996-11-04
KR100312267B1 (ko) 2002-06-22
JPH11152296A (ja) 1999-06-08
AU684027B2 (en) 1997-11-27
LU90872I2 (fr) 2002-03-12
RO113350B1 (ro) 1998-06-30
HU219599B (hu) 2001-05-28
PL317071A1 (en) 1997-03-03
NZ285416A (en) 1997-07-27
ZA953501B (en) 1996-05-02
NO964654L (no) 1996-11-04
TJ313B (en) 2001-08-06
CZ293455B6 (cs) 2004-05-12
DE69505296D1 (de) 1998-11-19
ES2122472T3 (es) 1998-12-16
NO308853B1 (no) 2000-11-06
EP0680967A1 (fr) 1995-11-08
DK0680967T3 (da) 1999-06-23
ATE172203T1 (de) 1998-10-15
FR2719587B1 (fr) 1996-07-12
AP9500744A0 (en) 1995-07-31
HUT75698A (en) 1997-05-28
CN1151746A (zh) 1997-06-11
BR9507700A (pt) 1997-08-19
MD1233B1 (ro) 1999-05-31
US5635485A (en) 1997-06-03
IL113245A (en) 1999-11-30
JPH0853489A (ja) 1996-02-27
FI964395L (fi) 1996-10-31
SI0680967T1 (en) 1999-02-28
JP4750755B2 (ja) 2011-08-17
DE10299001I1 (de) 2012-07-05
HU9904687D0 (en) 2000-03-28
WO1995029929A1 (fr) 1995-11-09
YU27095A (sh) 1998-05-15
FI964395A0 (fi) 1996-10-31
GEP19991538B (en) 1999-03-05
DE10299001I2 (de) 2012-07-05
JP3998828B2 (ja) 2007-10-31
JP4658902B2 (ja) 2011-03-23
HU227493B1 (en) 2011-07-28
HU9603038D0 (en) 1997-01-28
US6100404A (en) 2000-08-08
SK281707B6 (sk) 2001-07-10
NO2001027I1 (no) 2002-01-28
PL182034B1 (pl) 2001-10-31
MX9605208A (es) 1997-09-30
CN1088709C (zh) 2002-08-07
NL300077I1 (nl) 2002-03-01
RU2144036C1 (ru) 2000-01-10
SK140296A3 (en) 1998-04-08
YU49235B (sh) 2004-12-31
OA10319A (fr) 1997-10-07
CA2189271A1 (fr) 1995-11-09
LV11739B (en) 1997-08-20
LV11739A (lv) 1997-04-20
EP0680967B1 (fr) 1998-10-14
CN1229082A (zh) 1999-09-22
UA51618C2 (uk) 2002-12-16
CN1052984C (zh) 2000-05-31
FI111263B (fi) 2003-06-30
CA2189271C (fr) 2005-12-27
IL113245A0 (en) 1995-07-31
TW341573B (en) 1998-10-01
AU2449995A (en) 1995-11-29
EE03263B1 (et) 2000-04-17
BG100951A (en) 1997-08-29
HK1010732A1 (en) 1999-06-25
JP2992540B2 (ja) 1999-12-20
JP2007045847A (ja) 2007-02-22
FR2719587A1 (fr) 1995-11-10

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