DK1147121T3 - Ketolidantibiotika - Google Patents

Ketolidantibiotika

Info

Publication number
DK1147121T3
DK1147121T3 DK99959627T DK99959627T DK1147121T3 DK 1147121 T3 DK1147121 T3 DK 1147121T3 DK 99959627 T DK99959627 T DK 99959627T DK 99959627 T DK99959627 T DK 99959627T DK 1147121 T3 DK1147121 T3 DK 1147121T3
Authority
DK
Denmark
Prior art keywords
ketolide
Prior art date
Application number
DK99959627T
Other languages
English (en)
Inventor
Takushi Kaneko
William Thomas Mcmillen
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Application granted granted Critical
Publication of DK1147121T3 publication Critical patent/DK1147121T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/04Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Genetics & Genomics (AREA)
  • Pulmonology (AREA)
  • Biotechnology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Urology & Nephrology (AREA)
  • Otolaryngology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Dermatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Cephalosporin Compounds (AREA)
DK99959627T 1999-01-27 1999-12-28 Ketolidantibiotika DK1147121T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11734299P 1999-01-27 1999-01-27
PCT/IB1999/002051 WO2000044761A2 (en) 1999-01-27 1999-12-28 Ketolide antibiotics

Publications (1)

Publication Number Publication Date
DK1147121T3 true DK1147121T3 (da) 2004-04-13

Family

ID=22372371

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99959627T DK1147121T3 (da) 1999-01-27 1999-12-28 Ketolidantibiotika

Country Status (39)

Country Link
US (1) US6833444B2 (da)
EP (1) EP1147121B1 (da)
JP (1) JP3947360B2 (da)
KR (1) KR20020002380A (da)
CN (1) CN1342163A (da)
AP (1) AP2001002222A0 (da)
AT (1) ATE256694T1 (da)
AU (1) AU1675400A (da)
BG (1) BG105730A (da)
BR (1) BR9916969A (da)
CA (1) CA2359708C (da)
CO (1) CO5150229A1 (da)
CZ (1) CZ20012675A3 (da)
DE (1) DE69913738T2 (da)
DK (1) DK1147121T3 (da)
DZ (1) DZ3000A1 (da)
EA (1) EA200100623A1 (da)
EE (1) EE200100394A (da)
ES (1) ES2212655T3 (da)
HK (1) HK1042707A1 (da)
HN (1) HN2000000003A (da)
HR (1) HRP20010559A2 (da)
HU (1) HUP0105190A3 (da)
ID (1) ID30233A (da)
IL (1) IL144178A0 (da)
IS (1) IS5984A (da)
MA (1) MA26717A1 (da)
NO (1) NO20013680L (da)
OA (1) OA11753A (da)
PA (1) PA8489501A1 (da)
PE (1) PE20001422A1 (da)
PT (1) PT1147121E (da)
SI (1) SI1147121T1 (da)
SK (1) SK10172001A3 (da)
TN (1) TNSN00007A1 (da)
TR (1) TR200102128T2 (da)
UY (1) UY25990A1 (da)
WO (1) WO2000044761A2 (da)
ZA (1) ZA200105580B (da)

Families Citing this family (30)

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AP1060A (en) 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
EE200100394A (et) 1999-01-27 2002-10-15 Pfizer Products Inc. Ketoliidsed antibiootikumid
US6514944B2 (en) 1999-04-16 2003-02-04 Kosan Biosciences, Inc. Macrolide antiinfective agents
MXPA01010524A (es) 1999-04-16 2002-03-14 Kosan Biosciences Inc Agentes macrolidos anti-infecciosos.
US6451768B1 (en) 1999-04-16 2002-09-17 Kosan Biosciences, Inc. Macrolide antiinfective agents
US6939861B2 (en) 1999-04-16 2005-09-06 Kosan Biosciences, Inc. Amido macrolides
WO2000062783A2 (en) 1999-04-16 2000-10-26 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
US6590083B1 (en) 1999-04-16 2003-07-08 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
OA11945A (en) 1999-05-24 2006-04-13 Pfizer Prod Inc 13-Methyl erythromycin derivatives.
DE60104240T2 (de) 2000-06-30 2005-08-04 Pfizer Products Inc., Groton Makrolid-Antibiotika
US20020115621A1 (en) 2000-08-07 2002-08-22 Wei-Gu Su Macrolide antibiotics
PL365012A1 (en) * 2000-12-21 2004-12-27 Glaxo Group Limited Macrolide antibiotics
WO2003022289A1 (fr) * 2001-09-05 2003-03-20 Hokuriku Seiyaku Co., Ltd. Medicament contenant de l'erythromycine pour traiter ou prevenir la tuberculose
CA2801100A1 (en) 2003-03-10 2004-09-23 Optimer Pharmaceuticals, Inc. Macrolides and processes for their preparation
EP1794171A2 (en) * 2004-07-28 2007-06-13 Ranbaxy Laboratories, Ltd. Ketolide derivatives as antibacterial agents
ATE459633T1 (de) 2004-12-21 2010-03-15 Pfizer Prod Inc Makrolide
CN103193840A (zh) * 2006-05-01 2013-07-10 大正制药株式会社 大环内酯衍生物
EP2214484A4 (en) 2007-10-25 2013-01-02 Cempra Pharmaceuticals Inc PROCESS FOR PREPARING ANTIBACTERIAL MAKROLIDE AGENTS
SI2358379T1 (sl) 2008-10-24 2016-05-31 Cempra Pharmaceuticals, Inc. Postopki biološke obrambe z makrolidi, ki vsebujejo triazol
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
ES2608285T3 (es) 2009-09-10 2017-04-07 Cempra Pharmaceuticals, Inc. Procedimientos para el tratamiento de paludismo, tuberculosis y enfermedades por MAC
RU2650883C2 (ru) 2010-03-22 2018-04-18 Семпра Фармасьютикалз, Инк. Кристаллические формы макролида и их применение
EP2571506B1 (en) 2010-05-20 2017-05-10 Cempra Pharmaceuticals, Inc. Processes for preparing macrolides and ketolides and intermediates therefor
KR20130120458A (ko) 2010-09-10 2013-11-04 셈프라 파마슈티컬스, 인크. 질환을 치료하기 위한 수소결합 형성 플루오로 케토라이드
IN2014DN08939A (da) 2012-03-27 2015-05-22 Cempra Pharmaceuticals Inc
EP2968801B1 (en) 2013-03-14 2018-09-26 Cempra Pharmaceuticals, Inc. Methods for treating respiratory diseases and formulations therefor
CN105188712A (zh) 2013-03-15 2015-12-23 森普拉制药公司 用于制备大环内酯抗菌剂的收敛方法
US10390544B2 (en) 2013-03-28 2019-08-27 Fuji Oil Company Limited Mung bean protein gel composition and cheese-like food
CN106518939B (zh) * 2015-09-14 2019-12-31 江苏奥赛康药业有限公司 一种制备Solithromycin化合物的方法
CN110234323A (zh) * 2016-10-04 2019-09-13 Ti生物制药有限公司 具有抗菌活性的酮内酯

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YU43006B (en) 1981-03-06 1989-02-28 Pliva Pharm & Chem Works Process for preparing n-methyl-11-aza-10-deoxo-10-dihydro erythromycin and derivatives thereof
US4474768A (en) 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
US5141926A (en) 1990-04-18 1992-08-25 Abbott Laboratories Erythromycin derivatives
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FR2751656B1 (fr) 1996-07-24 1998-10-16 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
UA51730C2 (uk) 1996-09-04 2002-12-16 Ебботт Лабораторіз 6-o-заміщені кетоліди з антибактеріальною активністю, спосіб їх одержання (варіанти), фармацевтична композиція та спосіб регулювання бактеріальної інфекції у ссавців
FR2757168B1 (fr) 1996-12-12 1999-06-11 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2760017B1 (fr) 1997-02-27 1999-04-30 Hoechst Marion Roussel Inc Nouveaux derives de l'erytromycine, leur procede de preparation et leur application comme medicaments
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HN1998000159A (es) 1997-10-29 1999-02-09 Monsanto Co Derivados de 9- amino - 3 ceto eritromicina
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FR2771008B1 (fr) * 1997-11-17 2000-04-28 Hoechst Marion Roussel Inc Utilisation des ketolides pour la preparation de compositions pharmaceutiques destinees a prevenir les complications thrombotiques arterielles liees a l'atherosclerose
AP1060A (en) 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
FR2777282B1 (fr) 1998-04-08 2001-04-20 Hoechst Marion Roussel Inc Nouveaux derives de la 2-fluoro 3-de((2,6-dideoxy 3-c-methyl 3-0-methyl-alpha-l-ribohexopyranosyl) oxyl) 6-o-methyl 3-oxo erythromycine, leur procede de preparation et leur application a la synthese de principes actifs de medicaments
EP1115732B1 (en) 1998-09-22 2005-06-29 Pfizer Products Inc. Carbamate and carbazate ketolide antibiotics
US6100240A (en) 1998-10-09 2000-08-08 Pfizer Inc Macrolide derivatives
FR2785612A1 (fr) 1998-11-10 2000-05-12 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
AP2001002131A0 (en) 1998-11-03 2001-06-30 Pfizer Prod Inc Novel macrolide antibiotics.
FR2786188B1 (fr) 1998-11-24 2002-10-31 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur applicaion comme medicaments
WO2000034297A1 (en) 1998-12-10 2000-06-15 Pfizer Products Inc. Carbamate and carbazate ketolide antibiotics
EE200100394A (et) 1999-01-27 2002-10-15 Pfizer Products Inc. Ketoliidsed antibiootikumid
FR2789392B1 (fr) * 1999-02-04 2001-10-05 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
WO2000062783A2 (en) 1999-04-16 2000-10-26 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
MXPA01010524A (es) 1999-04-16 2002-03-14 Kosan Biosciences Inc Agentes macrolidos anti-infecciosos.
US6355620B1 (en) 1999-05-14 2002-03-12 Abbott Laboratories C-2 modified erythromycin derivatives
OA11945A (en) 1999-05-24 2006-04-13 Pfizer Prod Inc 13-Methyl erythromycin derivatives.
EP1114826A3 (en) 1999-12-29 2001-10-31 Pfizer Products Inc. Novel antibacterial and prokinetic macrolides
EP1122261A3 (en) 2000-01-31 2001-09-26 Pfizer Products Inc. 13 and 14-membered antibacterial macrolides
US20020061856A1 (en) 2000-04-24 2002-05-23 Yong-Jin Wu Novel tricyclic erythromycin derivatives
DE60104240T2 (de) 2000-06-30 2005-08-04 Pfizer Products Inc., Groton Makrolid-Antibiotika

Also Published As

Publication number Publication date
KR20020002380A (ko) 2002-01-09
EA200100623A1 (ru) 2002-02-28
EE200100394A (et) 2002-10-15
IL144178A0 (en) 2002-05-23
NO20013680D0 (no) 2001-07-26
AP2001002222A0 (en) 2001-09-30
CN1342163A (zh) 2002-03-27
SK10172001A3 (sk) 2002-06-04
HN2000000003A (es) 2001-02-02
DE69913738D1 (de) 2004-01-29
CA2359708A1 (en) 2000-08-03
WO2000044761A3 (en) 2001-01-04
EP1147121B1 (en) 2003-12-17
CO5150229A1 (es) 2002-04-29
WO2000044761A2 (en) 2000-08-03
PA8489501A1 (es) 2000-09-29
MA26717A1 (fr) 2004-12-20
ES2212655T3 (es) 2004-07-16
EP1147121A2 (en) 2001-10-24
HUP0105190A3 (en) 2003-03-28
CZ20012675A3 (cs) 2002-04-17
JP3947360B2 (ja) 2007-07-18
BG105730A (en) 2002-03-29
ID30233A (id) 2001-11-15
NO20013680L (no) 2001-09-19
DE69913738T2 (de) 2004-06-17
HRP20010559A2 (en) 2002-08-31
JP2002535414A (ja) 2002-10-22
HUP0105190A2 (hu) 2002-04-29
BR9916969A (pt) 2001-11-06
CA2359708C (en) 2005-10-25
US20020156027A1 (en) 2002-10-24
ATE256694T1 (de) 2004-01-15
TR200102128T2 (tr) 2001-12-21
TNSN00007A1 (fr) 2005-11-10
ZA200105580B (en) 2003-02-17
IS5984A (is) 2001-06-28
PT1147121E (pt) 2004-04-30
DZ3000A1 (fr) 2004-03-27
PE20001422A1 (es) 2000-12-18
AU1675400A (en) 2000-08-18
UY25990A1 (es) 2000-09-29
OA11753A (en) 2005-07-19
US6833444B2 (en) 2004-12-21
SI1147121T1 (en) 2004-04-30
HK1042707A1 (zh) 2002-08-23

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