WO2003022289A1 - Medicament contenant de l'erythromycine pour traiter ou prevenir la tuberculose - Google Patents

Medicament contenant de l'erythromycine pour traiter ou prevenir la tuberculose Download PDF

Info

Publication number
WO2003022289A1
WO2003022289A1 PCT/JP2002/008922 JP0208922W WO03022289A1 WO 2003022289 A1 WO2003022289 A1 WO 2003022289A1 JP 0208922 W JP0208922 W JP 0208922W WO 03022289 A1 WO03022289 A1 WO 03022289A1
Authority
WO
WIPO (PCT)
Prior art keywords
alkyl
tuberculosis
prevention
group represented
treatment
Prior art date
Application number
PCT/JP2002/008922
Other languages
English (en)
Japanese (ja)
Inventor
Toshihiko Yoshida
Yoshie Takahashi
Original Assignee
Hokuriku Seiyaku Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hokuriku Seiyaku Co., Ltd. filed Critical Hokuriku Seiyaku Co., Ltd.
Publication of WO2003022289A1 publication Critical patent/WO2003022289A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

L'invention concerne un médicament pour traiter et/ou prévenir la tuberculose, qui contient comme principe actif un dérivé d'érythromycine représenté par la formule générale (I), dans laquelle R représente hydrogène, méthyle ou éthyle ; R1 représente alkyle en C¿5-12?, cycloalkyle, (cycloalkyl)alkyle, aralkyle ou un groupe représenté par la formule (CH2)n-X-R5 ; R?2¿ représente hydrogène ou carbamoyle ; R3 représente acyle ou un groupe représenté par la formule C(=O)-Y-R6 ; R4 représente hydrogène ou alkyle ; R5 représente alkyle, alcoxyalkyle, alkylthioalkyle, alkylaminoalkyle, aryle ou aralkyle ; R6 représente alkyle, aryle ou aralkyle ; n représente un nombre entier compris entre 1 et 6 ; X représente oxygène, soufre ou un groupe représenté par NZ ; Y représente oxygène ou un groupe représenté par NH ; et Z représente hydrogène ou alkyle.
PCT/JP2002/008922 2001-09-05 2002-09-03 Medicament contenant de l'erythromycine pour traiter ou prevenir la tuberculose WO2003022289A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001268213 2001-09-05
JP2001-268213 2001-09-05

Publications (1)

Publication Number Publication Date
WO2003022289A1 true WO2003022289A1 (fr) 2003-03-20

Family

ID=19094233

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2002/008922 WO2003022289A1 (fr) 2001-09-05 2002-09-03 Medicament contenant de l'erythromycine pour traiter ou prevenir la tuberculose

Country Status (4)

Country Link
AR (1) AR036587A1 (fr)
PE (1) PE20030438A1 (fr)
UY (1) UY27429A1 (fr)
WO (1) WO2003022289A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005007143A2 (fr) * 2003-07-14 2005-01-27 The Board Of Trustees Of The University Of Illinois Procede pour traiter la tuberculose

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996024378A2 (fr) * 1995-02-10 1996-08-15 Worcester Foundation For Biomedical Research, Inc. Apport de composes exogenes
EP0895999A1 (fr) * 1997-08-06 1999-02-10 Pfizer Products Inc. Macrolides antibiotiques substitués C"-4
WO2000044761A2 (fr) * 1999-01-27 2000-08-03 Pfizer Products Inc. Antibiotiques cetolides
WO2000061593A1 (fr) * 1999-04-08 2000-10-19 Hokuriku Seiyaku Co., Ltd. Derives d'erythromycine
EP1122261A2 (fr) * 2000-01-31 2001-08-08 Pfizer Products Inc. Macrolides antibactériennes à 13 ou 14 chainons

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996024378A2 (fr) * 1995-02-10 1996-08-15 Worcester Foundation For Biomedical Research, Inc. Apport de composes exogenes
EP0895999A1 (fr) * 1997-08-06 1999-02-10 Pfizer Products Inc. Macrolides antibiotiques substitués C"-4
WO2000044761A2 (fr) * 1999-01-27 2000-08-03 Pfizer Products Inc. Antibiotiques cetolides
WO2000061593A1 (fr) * 1999-04-08 2000-10-19 Hokuriku Seiyaku Co., Ltd. Derives d'erythromycine
EP1122261A2 (fr) * 2000-01-31 2001-08-08 Pfizer Products Inc. Macrolides antibactériennes à 13 ou 14 chainons

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005007143A2 (fr) * 2003-07-14 2005-01-27 The Board Of Trustees Of The University Of Illinois Procede pour traiter la tuberculose
WO2005007143A3 (fr) * 2003-07-14 2005-06-30 Univ Illinois Procede pour traiter la tuberculose

Also Published As

Publication number Publication date
UY27429A1 (es) 2003-10-31
PE20030438A1 (es) 2003-07-03
AR036587A1 (es) 2004-09-22

Similar Documents

Publication Publication Date Title
NO950297L (no) Prolinamidderivater
EP0741970A4 (fr) Composition bactericide
CA2336412A1 (fr) Medicament pour le traitement du diabete
AU623733B2 (en) Benzofused-n-containing heterocyle derivatives
DK0644199T3 (da) Cykliske antimikrobielle peptider og fremstilling deraf
DK0759919T3 (da) Azolidindioner som antihyperglykæmiske midler
MX9702670A (es) Derivado de azol.
AU5910996A (en) Pyrrole derivatives and medicinal composition
BR0309558A (pt) Derivados de quinazolina e medicamentos
WO1993014767A3 (fr) Preparation pharmaceutique a base de rhamnolipides utilisee pour traiter les maladies dermatologiques, par exemple, les infections du virus du papillome
MXPA02006051A (es) Compuestos de amonio cuaternario ciclico.
EP1389612A4 (fr) Derives de phthalamide, insecticides a utilisation agricole et horticole, et procede d'application de ces derives
MX9206093A (es) Derivado de oxazolidona
AU689808B2 (en) Dithiocarbonimide derivative, fungicidal/insecticidal/ acaricidal agent containing said derivative as active ingredient, intermediate for use in production of said derivative and process for producing said derivative from said intermediate
WO2003022289A1 (fr) Medicament contenant de l'erythromycine pour traiter ou prevenir la tuberculose
EP1134216A4 (fr) Agents de souches et agents antichlamydia pharmacoresistants
WO2001062709A3 (fr) Utilisation de derives de 2-phenylene diamine pour le traitement d'infections
TW200502204A (en) Oligo acid derivatives
RU94033470A (ru) Циклогексановые производные, фармкомпозиция на их основе и способ лечения
TW200505338A (en) Pyrazole compound
TW200640887A (en) PPAR-activating compound
TH87424A (th) ไซโคลเฮกซิลซัลโฟนชนิดใหม่
CA2348319A1 (fr) Derives de cyclohexenol et medicament les contenant

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BY BZ CA CH CN CO CR CU CZ DE DM DZ EC EE ES FI GB GD GE GH HR HU ID IL IN IS KE KG KR KZ LC LR LS LT LU LV MA MD MG MK MN MX MZ NO NZ OM PH PL PT RO RU SE SG SI SK SL TJ TM TN TR TT TZ UG US UZ VC VN YU ZA ZM

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): GH GM KE LS MW MZ SD SL SZ UG ZM ZW AM AZ BY KG KZ RU TJ TM AT BE BG CH CY CZ DK EE ES FI FR GB GR IE IT LU MC PT SE SK TR BF BJ CF CG CI GA GN GQ GW ML MR NE SN TD TG

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
121 Ep: the epo has been informed by wipo that ep was designated in this application
122 Ep: pct application non-entry in european phase