SI0680967T1 - Erythromycin derivatives, their process of preparation and their use as medicaments - Google Patents

Erythromycin derivatives, their process of preparation and their use as medicaments

Info

Publication number
SI0680967T1
SI0680967T1 SI9530184T SI9530184T SI0680967T1 SI 0680967 T1 SI0680967 T1 SI 0680967T1 SI 9530184 T SI9530184 T SI 9530184T SI 9530184 T SI9530184 T SI 9530184T SI 0680967 T1 SI0680967 T1 SI 0680967T1
Authority
SI
Slovenia
Prior art keywords
medicaments
preparation
erythromycin derivatives
erythromycin
derivatives
Prior art date
Application number
SI9530184T
Other languages
English (en)
Slovenian (sl)
Inventor
Constantin Agouridas
Jean-Francois Chantot
Alexis Denis
D'ambrieres Solange Gouin
Martret Odile Le
Original Assignee
Hoechst Marion Roussel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel filed Critical Hoechst Marion Roussel
Publication of SI0680967T1 publication Critical patent/SI0680967T1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Indole Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
SI9530184T 1994-05-03 1995-05-02 Erythromycin derivatives, their process of preparation and their use as medicaments SI0680967T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9405368A FR2719587B1 (fr) 1994-05-03 1994-05-03 Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
EP95400987A EP0680967B1 (fr) 1994-05-03 1995-05-02 Dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments

Publications (1)

Publication Number Publication Date
SI0680967T1 true SI0680967T1 (en) 1999-02-28

Family

ID=9462785

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9530184T SI0680967T1 (en) 1994-05-03 1995-05-02 Erythromycin derivatives, their process of preparation and their use as medicaments

Country Status (43)

Country Link
US (2) US5635485A (xx)
EP (1) EP0680967B1 (xx)
JP (4) JP2992540B2 (xx)
KR (1) KR100312267B1 (xx)
CN (2) CN1052984C (xx)
AP (1) AP558A (xx)
AT (1) ATE172203T1 (xx)
AU (1) AU684027B2 (xx)
BG (1) BG63087B1 (xx)
BR (1) BR9507700A (xx)
CA (1) CA2189271C (xx)
CZ (1) CZ293455B6 (xx)
DE (2) DE10299001I2 (xx)
DK (1) DK0680967T3 (xx)
DZ (1) DZ1878A1 (xx)
EE (1) EE03263B1 (xx)
ES (1) ES2122472T3 (xx)
FI (1) FI111263B (xx)
FR (1) FR2719587B1 (xx)
GE (1) GEP19991538B (xx)
HK (1) HK1010732A1 (xx)
HU (2) HU227493B1 (xx)
IL (1) IL113245A (xx)
LU (1) LU90872I2 (xx)
LV (1) LV11739B (xx)
MA (1) MA23534A1 (xx)
MD (1) MD1233C2 (xx)
NL (1) NL300077I1 (xx)
NO (2) NO308853B1 (xx)
NZ (1) NZ285416A (xx)
OA (1) OA10319A (xx)
PL (1) PL182034B1 (xx)
RO (1) RO113350B1 (xx)
RU (1) RU2144036C1 (xx)
SI (1) SI0680967T1 (xx)
SK (1) SK281707B6 (xx)
TJ (1) TJ313B (xx)
TN (1) TNSN95049A1 (xx)
TW (1) TW341573B (xx)
UA (1) UA51618C2 (xx)
WO (1) WO1995029929A1 (xx)
YU (1) YU49235B (xx)
ZA (1) ZA953501B (xx)

Families Citing this family (85)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE275132T1 (de) * 1995-06-27 2004-09-15 Takeda Chemical Industries Ltd 4-acylamino(halogen)alkyl-chinolin derivate, deren herstellung und deren verwendung als melatonin-agonisten
FR2742757B1 (fr) * 1995-12-22 1998-01-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
UA51730C2 (uk) * 1996-09-04 2002-12-16 Ебботт Лабораторіз 6-o-заміщені кетоліди з антибактеріальною активністю, спосіб їх одержання (варіанти), фармацевтична композиція та спосіб регулювання бактеріальної інфекції у ссавців
DE69733369T2 (de) * 1996-09-04 2006-01-26 Abbott Laboratories, Abbott Park 6-o-Substituierte Ketoliden mit antibakteriellen Wirking
FR2757168B1 (fr) * 1996-12-12 1999-06-11 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2760017B1 (fr) * 1997-02-27 1999-04-30 Hoechst Marion Roussel Inc Nouveaux derives de l'erytromycine, leur procede de preparation et leur application comme medicaments
US5780605A (en) * 1997-09-08 1998-07-14 Abbott Laboratories 6,9-bridged erythromycin derivatives
FR2771008B1 (fr) * 1997-11-17 2000-04-28 Hoechst Marion Roussel Inc Utilisation des ketolides pour la preparation de compositions pharmaceutiques destinees a prevenir les complications thrombotiques arterielles liees a l'atherosclerose
JP4573925B2 (ja) * 1998-07-09 2010-11-04 アベンティス・ファーマ・ソシエテ・アノニム 新規のエリスロマイシン誘導体、その製造方法及びその薬剤としての使用
FR2781484B1 (fr) * 1998-07-21 2001-08-10 Hoechst Marion Roussel Inc Nouveaux derives de la 6-deoxy erythromycine, leur procede de preparation et leur application comme medicaments
EP1115732B1 (en) 1998-09-22 2005-06-29 Pfizer Products Inc. Carbamate and carbazate ketolide antibiotics
FR2785612A1 (fr) * 1998-11-10 2000-05-12 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2786188B1 (fr) * 1998-11-24 2002-10-31 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur applicaion comme medicaments
TW526202B (en) * 1998-11-27 2003-04-01 Shionogi & Amp Co Broad spectrum cephem having benzo[4,5-b]pyridium methyl group of antibiotic activity
WO2000034297A1 (en) 1998-12-10 2000-06-15 Pfizer Products Inc. Carbamate and carbazate ketolide antibiotics
EE200100394A (et) * 1999-01-27 2002-10-15 Pfizer Products Inc. Ketoliidsed antibiootikumid
FR2789392B1 (fr) * 1999-02-04 2001-10-05 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
US6054435A (en) * 1999-03-19 2000-04-25 Abbott Laboratories 6-O-substituted macrolides having antibacterial activity
WO2000062783A2 (en) * 1999-04-16 2000-10-26 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
US6939861B2 (en) * 1999-04-16 2005-09-06 Kosan Biosciences, Inc. Amido macrolides
US6590083B1 (en) 1999-04-16 2003-07-08 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
US6514944B2 (en) 1999-04-16 2003-02-04 Kosan Biosciences, Inc. Macrolide antiinfective agents
US6451768B1 (en) 1999-04-16 2002-09-17 Kosan Biosciences, Inc. Macrolide antiinfective agents
MXPA01010524A (es) 1999-04-16 2002-03-14 Kosan Biosciences Inc Agentes macrolidos anti-infecciosos.
OA11945A (en) * 1999-05-24 2006-04-13 Pfizer Prod Inc 13-Methyl erythromycin derivatives.
FR2797875B1 (fr) * 1999-08-26 2001-10-19 Hoechst Marion Roussel Inc Agglomerats spheriques de telithromycine, leur procede de preparation et leur application dans la preparation de formes pharmaceutiques
US6946446B2 (en) 2000-02-24 2005-09-20 Abbott Laboratories Anti-infective agents useful against multidrug-resistant strains of bacteria
BR0113472A (pt) 2000-08-22 2003-07-01 Basilea Pharmaceutica Ag Macrolìdeos com atividade antibacteriana
FR2821747B1 (fr) * 2001-03-09 2004-07-02 Ethypharm Lab Prod Ethiques Suspension de telithromycine a gout masque
JP4509553B2 (ja) * 2001-07-03 2010-07-21 ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド 抗菌活性を有するｃ１２修飾エリスロマイシンマクロライドおよびケトライド
US8063021B2 (en) * 2002-01-17 2011-11-22 Kosan Biosciences Incorporated Ketolide anti-infective compounds
US6995143B2 (en) 2002-02-28 2006-02-07 Basilea Pharmaceutica Ag Macrolides with antibacterial activity
DE60327341D1 (de) 2002-07-08 2009-06-04 Glaxosmithkline Zagreb Hybridmoleküle von makroliden mit steroidalen/nicht-steroidalen antientzündlich aktiven molekülen
CA2489402A1 (en) 2002-07-08 2004-01-15 Pliva-Istrazivacki Institut D.O.O. New compounds, compositions and methods for treatment of inflammatory diseases and conditions
US20040013737A1 (en) * 2002-07-19 2004-01-22 Philippe Becourt Taste masked oral composition of telithromycin
WO2004009059A1 (en) * 2002-07-19 2004-01-29 Aventis Pharma S.A. Taste masked oral composition of telithromycin
AR043050A1 (es) 2002-09-26 2005-07-13 Rib X Pharmaceuticals Inc Compuestos heterociclicos bifuncionales y metodos para preparar y usar los mismos
US6916934B2 (en) * 2003-02-11 2005-07-12 Aventis Pharma Deutschland Gmbh Process for preparing pyridine-substituted amino ketal derivatives
CA2801100A1 (en) 2003-03-10 2004-09-23 Optimer Pharmaceuticals, Inc. Macrolides and processes for their preparation
US7163924B2 (en) * 2003-04-25 2007-01-16 Chiron Corporation Ketolide derivatives
US20050101548A1 (en) * 2003-09-12 2005-05-12 Xiaodong Lin Antimicrobial derivatives
GB0402578D0 (en) * 2004-02-05 2004-03-10 Cambridge Theranostics Ltd Methods of treatment of atherosclerosis
JP5383037B2 (ja) 2004-02-27 2014-01-08 リブ−エックス ファーマシューティカルズ，インコーポレイテッド 大環状化合物およびそれらを製造し使用する方法
ES2294733T3 (es) * 2004-04-28 2008-04-01 Alembic Limited Proceso para la preparacion de telitromicina.
EP1794171A2 (en) * 2004-07-28 2007-06-13 Ranbaxy Laboratories, Ltd. Ketolide derivatives as antibacterial agents
EP1807439A2 (en) * 2004-10-25 2007-07-18 Ranbaxy Laboratories Limited Ketolide derivatives as antibacterial agents
ATE459633T1 (de) * 2004-12-21 2010-03-15 Pfizer Prod Inc Makrolide
CN101116154A (zh) * 2005-02-08 2008-01-30 株式会社村田制作所 表面安装型负特性热敏电阻
FR2882522B1 (fr) 2005-02-25 2007-04-13 Aventis Pharma Sa Composition pharmaceutique solide comprenant de la telithromycine
WO2006129257A2 (en) * 2005-05-30 2006-12-07 Ranbaxy Laboratories Limited Ketolide derivatives as antibacterial agents
WO2007039914A2 (en) * 2005-10-06 2007-04-12 Alembic Limited Novel polymorphs of telithromycin
WO2007049296A2 (en) * 2005-10-28 2007-05-03 Alembic Limited Amorphous form of telithromycin
WO2007059307A2 (en) * 2005-11-15 2007-05-24 Teva Pharmaceutical Industries Ltd. Crystalline and amorphous forms of telithromycin
EP1954294A2 (en) * 2005-11-23 2008-08-13 Ranbaxy Laboratories Limited Use of macrolide derivatives for treating acne
EP1957508A2 (en) * 2005-11-23 2008-08-20 Ranbaxy Laboratories Limited Ketolide derivatives as antibacterial agents
EP1960413A2 (en) * 2005-11-23 2008-08-27 Ranbaxy Laboratories Limited Macrolides derivatives as antibacterial agents
US7595300B2 (en) 2005-12-13 2009-09-29 Kosan Biosciences Incorporated 7-quinolyl ketolide antibacterial agents
GB0600238D0 (en) * 2006-01-06 2006-02-15 Sandoz Ag Organic compounds
JP5015016B2 (ja) * 2006-02-07 2012-08-29 大正製薬株式会社 １０ａ−アザライド化合物
KR20090042971A (ko) 2006-08-24 2009-05-04 욱크하르트 리서치 센터 항미생물 활성을 갖는 신규한 마크로라이드 및 케토라이드
WO2008023383A1 (en) * 2006-08-25 2008-02-28 Alembic Limited Novel process for the preparation of telithromycin
ES2306590B1 (es) * 2006-12-15 2009-08-07 Ercros Industrial,S .A. Formas cristalinas i y ii de telitromicina.
EP2177526A4 (en) 2007-08-06 2012-08-22 Taisho Pharmaceutical Co Ltd 10A-AZALIDE COMPOUND CROSS-LINKED IN POSITION 10A AND POSITION 12
US20090075917A1 (en) * 2007-09-19 2009-03-19 Protia, Llc Deuterium-enriched telithromycin
US7926879B2 (en) 2007-09-20 2011-04-19 Herman Miller, Inc. Load support structure
WO2009053259A1 (en) * 2007-10-25 2009-04-30 Sandoz Ag Process for the production of telithromycin
EP2214484A4 (en) * 2007-10-25 2013-01-02 Cempra Pharmaceuticals Inc PROCESS FOR PREPARING ANTIBACTERIAL MAKROLIDE AGENTS
US8299035B2 (en) * 2008-05-15 2012-10-30 Taisho Pharmaceutucal Co., Ltd. 10a-azalide compound having 4-membered ring structure
SI2358379T1 (sl) * 2008-10-24 2016-05-31 Cempra Pharmaceuticals, Inc. Postopki biološke obrambe z makrolidi, ki vsebujejo triazol
JP5607149B2 (ja) 2009-05-27 2014-10-15 ウォックハート リサーチ センター 抗菌活性を有するケトライド化合物
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
ES2608285T3 (es) 2009-09-10 2017-04-07 Cempra Pharmaceuticals, Inc. Procedimientos para el tratamiento de paludismo, tuberculosis y enfermedades por MAC
RU2650883C2 (ru) 2010-03-22 2018-04-18 Семпра Фармасьютикалз, Инк. Кристаллические формы макролида и их применение
EP2571506B1 (en) 2010-05-20 2017-05-10 Cempra Pharmaceuticals, Inc. Processes for preparing macrolides and ketolides and intermediates therefor
KR20130120458A (ko) * 2010-09-10 2013-11-04 셈프라 파마슈티컬스, 인크. 질환을 치료하기 위한 수소결합 형성 플루오로 케토라이드
AU2011340204B2 (en) 2010-12-09 2016-04-14 Wockhardt Limited Ketolide compounds
AR085286A1 (es) 2011-02-21 2013-09-18 Taisho Pharmaceutical Co Ltd Derivado de macrolido sustituido en la posicion c-4
US9206214B2 (en) 2011-03-01 2015-12-08 Wockhardt Ltd. Process for preparation of ketolide intermediates
ES2603227T3 (es) 2011-03-22 2017-02-24 Wockhardt Limited Proceso para la preparación de compuestos cetólidos
IN2014DN08939A (xx) 2012-03-27 2015-05-22 Cempra Pharmaceuticals Inc
EP2968801B1 (en) 2013-03-14 2018-09-26 Cempra Pharmaceuticals, Inc. Methods for treating respiratory diseases and formulations therefor
CN105188712A (zh) 2013-03-15 2015-12-23 森普拉制药公司 用于制备大环内酯抗菌剂的收敛方法
CN105524132B (zh) * 2014-09-30 2019-07-02 中国医学科学院药物研究所 含有喹啉取代基的红霉素a酮内酯类抗生素衍生物、其制备方法及应用
DE102015201783A1 (de) 2015-02-02 2016-08-04 Friedrich Baur Verfahren zur Herstellung eines Füllstoffs aus Textilfasern sowie Textil mit einem solchen Füllstoff
CN107129514B (zh) * 2016-03-02 2019-12-13 中国医学科学院药物研究所 红霉素a酮内酯类抗生素衍生物、其制备方法及应用

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2833140A1 (de) * 1978-07-28 1980-02-07 Boehringer Sohn Ingelheim Neue n-substituierte heterocyclen
IE810250L (en) * 1980-02-11 1981-08-11 Berlex Lab N-(3-phenoxy-2-hydroxypropyl) benzimidazole -1-¹alkanamines.
US4434174A (en) * 1980-02-11 1984-02-28 Berlex Laboratories, Inc. Treating cardiovascular diseases with N-(3-phenoxy-2-hydroxypropyl)benzimidazole-1-alkanamines
US4568687A (en) * 1983-02-28 1986-02-04 American Cyanamid Company N-[2-4-(1H-Imidazol-1-yl)alkyl]-arylamides and pharmaceutical compositions
ZA84949B (en) * 1983-04-06 1984-09-26 American Cyanamid Co Substituted-n-(2-4-(1h-imidazol-1-yl)alkyl)substituted amides
US4489089A (en) * 1983-04-06 1984-12-18 American Cyanamid Company Substituted N-[ω-(1H-imidazol-1-yl)alkyl]-amides
AU573828B2 (en) * 1984-05-17 1988-06-23 E.R. Squibb & Sons, Inc. Tetrahydronaphthalenols
GB8425104D0 (en) * 1984-10-04 1984-11-07 Ici America Inc Amide derivatives
DE3540376A1 (de) * 1985-11-14 1987-05-21 Bayer Ag Verfahren zur inhibierung der wasserstoffinduzierten korrosion von metallischen werkstoffen
DE3750023T2 (de) * 1986-10-29 1994-09-29 Pfizer Verfahren zur Herstellung von 2-(1-Pentyl-3-guanidino)-4-(2-methyl-4-imidazolyl)Thiazol und dessen kristallinisches Dihydrochlorid-Trihydrat.
DE3930669A1 (de) * 1989-09-14 1991-03-28 Basf Ag Verfahren zur herstellung von uretdiongruppen aufweisenden polyisocyanaten
JP2899028B2 (ja) * 1989-12-01 1999-06-02 協和醗酵工業株式会社 ジベンゾオキセピン誘導体
IL114589A (en) * 1990-11-21 1999-12-22 Roussel Uclaf Intermediates for the preparation of the history of erythromycin
ATE157368T1 (de) * 1990-11-28 1997-09-15 Taisho Pharmaceutical Co Ltd 6-0-methylerythromycin a-derivat
FR2692579B1 (fr) * 1992-06-19 1995-06-02 Roussel Uclaf Nouveaux dérivés de la picromycine, leur procédé de préparation et leur application comme médicaments.
FR2697524B1 (fr) * 1992-11-05 1994-12-23 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
US5527780A (en) * 1992-11-05 1996-06-18 Roussel Uclaf Erythromycin derivatives
TW370529B (en) * 1992-12-17 1999-09-21 Pfizer Pyrazolopyrimidines
HRP930014A2 (en) * 1993-01-08 1994-08-31 Pliva Pharm & Chem Works 9-deoxo-9a-aza-11-deoxy-9a-homoeritromycin a 9a, 11-cyclic carbamates

Also Published As

Publication number Publication date
SK281707B6 (sk) 2001-07-10
IL113245A (en) 1999-11-30
MD1233C2 (ro) 2000-10-31
JP4750755B2 (ja) 2011-08-17
ATE172203T1 (de) 1998-10-15
RU2144036C1 (ru) 2000-01-10
TNSN95049A1 (fr) 1996-02-06
UA51618C2 (uk) 2002-12-16
JP4658902B2 (ja) 2011-03-23
BR9507700A (pt) 1997-08-19
US5635485A (en) 1997-06-03
DE69505296D1 (de) 1998-11-19
OA10319A (fr) 1997-10-07
TJ313B (en) 2001-08-06
JPH0853489A (ja) 1996-02-27
FI111263B (fi) 2003-06-30
DZ1878A1 (fr) 2002-02-17
AP558A (en) 1996-11-07
AU2449995A (en) 1995-11-29
DE10299001I1 (de) 2012-07-05
CN1088709C (zh) 2002-08-07
EP0680967B1 (fr) 1998-10-14
YU27095A (sh) 1998-05-15
AP9500744A0 (en) 1995-07-31
EE03263B1 (et) 2000-04-17
NO964654D0 (no) 1996-11-04
BG63087B1 (bg) 2001-03-30
US6100404A (en) 2000-08-08
CN1052984C (zh) 2000-05-31
MX9605208A (es) 1997-09-30
CA2189271A1 (fr) 1995-11-09
CZ321496A3 (en) 1997-08-13
DE10299001I2 (de) 2012-07-05
BG100951A (en) 1997-08-29
DK0680967T3 (da) 1999-06-23
NO308853B1 (no) 2000-11-06
DE69505296T2 (de) 1999-04-22
IL113245A0 (en) 1995-07-31
LV11739A (lv) 1997-04-20
MD1233B1 (en) 1999-05-31
MA23534A1 (fr) 1995-12-31
JP3998828B2 (ja) 2007-10-31
CN1151746A (zh) 1997-06-11
HU227493B1 (en) 2011-07-28
HU9603038D0 (en) 1997-01-28
LU90872I2 (fr) 2002-03-12
TW341573B (en) 1998-10-01
RO113350B1 (ro) 1998-06-30
WO1995029929A1 (fr) 1995-11-09
PL317071A1 (en) 1997-03-03
JP2007045847A (ja) 2007-02-22
CA2189271C (fr) 2005-12-27
NO2001027I1 (no) 2002-01-28
HUT75698A (en) 1997-05-28
CZ293455B6 (cs) 2004-05-12
NL300077I1 (nl) 2002-03-01
KR100312267B1 (ko) 2002-06-22
ZA953501B (en) 1996-05-02
SK140296A3 (en) 1998-04-08
NO964654L (no) 1996-11-04
FR2719587B1 (fr) 1996-07-12
FR2719587A1 (fr) 1995-11-10
AU684027B2 (en) 1997-11-27
LV11739B (en) 1997-08-20
ES2122472T3 (es) 1998-12-16
EP0680967A1 (fr) 1995-11-08
JP2992540B2 (ja) 1999-12-20
HU219599B (hu) 2001-05-28
JPH11152296A (ja) 1999-06-08
FI964395A (fi) 1996-10-31
HK1010732A1 (en) 1999-06-25
NZ285416A (en) 1997-07-27
CN1229082A (zh) 1999-09-22
PL182034B1 (pl) 2001-10-31
GEP19991538B (en) 1999-03-05
YU49235B (sh) 2004-12-31
JP2007269810A (ja) 2007-10-18
FI964395A0 (fi) 1996-10-31
HU9904687D0 (en) 2000-03-28

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