KR20160137599A - C-met 길항제로의 암 치료 및 이것과 hgf 발현과의 상관관계 - Google Patents

C-met 길항제로의 암 치료 및 이것과 hgf 발현과의 상관관계 Download PDF

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KR20160137599A
KR20160137599A KR1020167029550A KR20167029550A KR20160137599A KR 20160137599 A KR20160137599 A KR 20160137599A KR 1020167029550 A KR1020167029550 A KR 1020167029550A KR 20167029550 A KR20167029550 A KR 20167029550A KR 20160137599 A KR20160137599 A KR 20160137599A
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hgf
patient
antibody
biomarker
cancer
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Korean (ko)
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하트무트 코에펜
시이 판
산드라 로스트
웨이 유
데이비드 샤메스
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제넨테크, 인크.
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
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    • G06—COMPUTING OR CALCULATING; COUNTING
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    • A61K2039/507—Comprising a combination of two or more separate antibodies
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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    • C07—ORGANIC CHEMISTRY
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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    • C12Q2531/00—Reactions of nucleic acids characterised by
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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KR1020167029550A 2014-03-24 2015-03-24 C-met 길항제로의 암 치료 및 이것과 hgf 발현과의 상관관계 Withdrawn KR20160137599A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201461969706P 2014-03-24 2014-03-24
US61/969,706 2014-03-24
US201461985316P 2014-04-28 2014-04-28
US61/985,316 2014-04-28
PCT/US2015/022282 WO2015148531A1 (en) 2014-03-24 2015-03-24 Cancer treatment with c-met antagonists and correlation of the latter with hgf expression

Publications (1)

Publication Number Publication Date
KR20160137599A true KR20160137599A (ko) 2016-11-30

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KR1020167029550A Withdrawn KR20160137599A (ko) 2014-03-24 2015-03-24 C-met 길항제로의 암 치료 및 이것과 hgf 발현과의 상관관계

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US (1) US10240207B2 (enExample)
EP (1) EP3122900A1 (enExample)
JP (1) JP2017516458A (enExample)
KR (1) KR20160137599A (enExample)
CN (1) CN107002119A (enExample)
BR (1) BR112016021383A2 (enExample)
CA (1) CA2943329A1 (enExample)
MA (1) MA39776A (enExample)
MX (1) MX2016012285A (enExample)
RU (1) RU2016141385A (enExample)
WO (1) WO2015148531A1 (enExample)

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CN105734159B (zh) * 2016-04-29 2019-04-05 北京泱深生物信息技术有限公司 食管鳞癌的分子标记物
JP6730525B2 (ja) 2016-11-21 2020-07-29 ナノストリング テクノロジーズ，インコーポレイティド 化学組成物とそれを利用する方法
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CN111032692A (zh) * 2017-08-08 2020-04-17 豪夫迈·罗氏有限公司 一种dlbcl患者亚组的奥滨尤妥珠单抗治疗
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