KR100898094B1 - 카스파제의 억제제 - Google Patents

카스파제의 억제제 Download PDF

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Publication number
KR100898094B1
KR100898094B1 KR1020007010376A KR20007010376A KR100898094B1 KR 100898094 B1 KR100898094 B1 KR 100898094B1 KR 1020007010376 A KR1020007010376 A KR 1020007010376A KR 20007010376 A KR20007010376 A KR 20007010376A KR 100898094 B1 KR100898094 B1 KR 100898094B1
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KR
South Korea
Prior art keywords
alkyl
aryl
heteroaryl
optionally substituted
cycloalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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KR1020007010376A
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English (en)
Korean (ko)
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KR20010042038A (ko
Inventor
워너메이커마리온더블유.
베미스가이더블유.
샤리프슨폴에스.
라우퍼데이비드제이.
멀리칸마이클디.
무르코마크에이.
윌슨케이쓰피.
자넷카제임스더블유.
데이비스로버트제이.
그릴로뜨앤느-라우르
시잔
포스터코르넬리아제이.
Original Assignee
버텍스 파마슈티칼스 인코포레이티드
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Publication of KR20010042038A publication Critical patent/KR20010042038A/ko
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Publication of KR100898094B1 publication Critical patent/KR100898094B1/ko
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
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  • Health & Medical Sciences (AREA)
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  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Neurosurgery (AREA)
  • Communicable Diseases (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pain & Pain Management (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Crystallography & Structural Chemistry (AREA)
KR1020007010376A 1998-03-19 1999-03-19 카스파제의 억제제 Expired - Lifetime KR100898094B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7877098P 1998-03-19 1998-03-19
US60/078,770 1998-03-19

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KR1020087002806A Division KR100928878B1 (ko) 1998-03-19 1999-03-19 카스파제의 억제제

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KR20010042038A KR20010042038A (ko) 2001-05-25
KR100898094B1 true KR100898094B1 (ko) 2009-05-18

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KR1020007010376A Expired - Lifetime KR100898094B1 (ko) 1998-03-19 1999-03-19 카스파제의 억제제
KR1020087002806A Expired - Lifetime KR100928878B1 (ko) 1998-03-19 1999-03-19 카스파제의 억제제

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US (3) US6531474B1 (enExample)
EP (6) EP2261234A3 (enExample)
JP (3) JP4594520B2 (enExample)
KR (2) KR100898094B1 (enExample)
CN (1) CN1321129C (enExample)
AP (1) AP2000001919A0 (enExample)
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AT (1) ATE410439T1 (enExample)
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BR (2) BR9909660A (enExample)
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