JPH0784437B2 - 複素環レチノイド - Google Patents

複素環レチノイド

Info

Publication number
JPH0784437B2
JPH0784437B2 JP60207724A JP20772485A JPH0784437B2 JP H0784437 B2 JPH0784437 B2 JP H0784437B2 JP 60207724 A JP60207724 A JP 60207724A JP 20772485 A JP20772485 A JP 20772485A JP H0784437 B2 JPH0784437 B2 JP H0784437B2
Authority
JP
Japan
Prior art keywords
group
acid
formula
tetramethyl
tetrahydro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP60207724A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6185360A (ja
Inventor
ブラハム・シユルート
ジヤツク・ウスタツシユ
ジヤン‐ミシエル・ブルナルドン
Original Assignee
サントル・アンテルナシヨナル・ド・ルシエルシユ・デルマトロジツク・セ．イ．エール．デ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by サントル・アンテルナシヨナル・ド・ルシエルシユ・デルマトロジツク・セ．イ．エール．デ filed Critical サントル・アンテルナシヨナル・ド・ルシエルシユ・デルマトロジツク・セ．イ．エール．デ
Publication of JPS6185360A publication Critical patent/JPS6185360A/ja
Publication of JPH0784437B2 publication Critical patent/JPH0784437B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D263/57—Aryl or substituted aryl radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/18—Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
    • C07D277/66—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2 with aromatic rings or ring systems directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cosmetics (AREA)
  • Indole Compounds (AREA)
  • Furan Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP60207724A 1984-09-19 1985-09-18 複素環レチノイド Expired - Fee Related JPH0784437B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
LU85544A LU85544A1 (fr) 1984-09-19 1984-09-19 Derives heterocycliques aromatiques,leur procede de preparation et leur application dans les domaines therapeutique et cosmetique
LU85544 1984-09-19

Publications (2)

Publication Number Publication Date
JPS6185360A JPS6185360A (ja) 1986-04-30
JPH0784437B2 true JPH0784437B2 (ja) 1995-09-13

Family

ID=19730321

Family Applications (1)

Application Number Title Priority Date Filing Date
JP60207724A Expired - Fee Related JPH0784437B2 (ja) 1984-09-19 1985-09-18 複素環レチノイド

Country Status (21)

Country Link
US (3) US4740519A (en, 2012)
JP (1) JPH0784437B2 (en, 2012)
AR (1) AR243504A1 (en, 2012)
AT (2) AT395714B (en, 2012)
AU (2) AU578310B2 (en, 2012)
BE (2) BE903254A (en, 2012)
CA (2) CA1256804A (en, 2012)
CH (2) CH665841A5 (en, 2012)
DE (2) DE3546907C2 (en, 2012)
DK (1) DK169475B1 (en, 2012)
ES (1) ES8608487A1 (en, 2012)
FR (1) FR2570377B1 (en, 2012)
GB (3) GB2164648B (en, 2012)
GR (1) GR852270B (en, 2012)
IT (1) IT1209663B (en, 2012)
LU (1) LU85544A1 (en, 2012)
MX (1) MX166783B (en, 2012)
NL (1) NL192878C (en, 2012)
PT (1) PT81132B (en, 2012)
SE (2) SE461466B (en, 2012)
ZA (1) ZA857158B (en, 2012)

Families Citing this family (174)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4448006A (en) 1981-05-28 1984-05-15 Donn Incorporated Grid ceiling structure and method of converting
LU86258A1 (fr) * 1986-01-21 1987-09-03 Rech Dermatologiques C I R D S Composes benzamido aromatique,leur procede de preparation et leur utilisation en medecine humaine ou veterinaire et en cosmetique
FR2603280B1 (fr) * 1986-08-29 1988-10-28 Cird Nouveau compose marque au tritium, sa preparation et son application notamment dans la determination de l'affinite des retinoides pour leur recepteur cellulaire
NZ223237A (en) * 1987-01-22 1991-03-26 Shiseido Co Ltd Hair growth promoting agent and compositions
US5149705A (en) * 1987-03-13 1992-09-22 Allergan, Inc. Acetylenes disubstituted with a heteroaromatic group and a tetralin group and having retinoid like activity
US5602130A (en) * 1987-03-20 1997-02-11 Allergan Disubstituted acetylenes bearing heteroaromatic and heterobicyclic groups having retinoid like activity
US5264578A (en) * 1987-03-20 1993-11-23 Allergan, Inc. Disubstituted acetylenes bearing heterobicyclic groups and heteroaromatic or phenyl groups having retinoid like activity
US5234926A (en) * 1987-03-20 1993-08-10 Allergan, Inc. Disubstituted acetylenes bearing heteroaromatic and heterobicyclic groups having retinoid like activity
FR2614618B1 (fr) * 1987-04-30 1989-07-07 Cird Derives heterocycliques polycycliques, leur procede de preparation et leur utilisation en medecine humaine et veterinaire
LU87038A1 (fr) * 1987-11-04 1989-06-14 Oreal Esters aromatiques d'antibiotiques macrolidiques et lincosamidiques,leur procede de preparation et compositions pharmaceutiques et cosmetiques les contenant
KR0139216B1 (ko) * 1988-04-11 1998-05-01 제임스 엠. 캐내지 레티노이드 유사활성을 갖는 페놀 또는 벤조산의 테트랄린 에스테르
US5366986A (en) * 1988-04-15 1994-11-22 T Cell Sciences, Inc. Compounds which inhibit complement and/or suppress immune activity
US5173499A (en) * 1988-04-15 1992-12-22 T Cell Sciences, Inc. Compounds which inhibit complement and/or suppress immune activity
US5506247A (en) * 1988-04-15 1996-04-09 T Cell Sciences, Inc. Compounds that inhibit complement and/or suppress immune activity
DE3830054A1 (de) * 1988-09-03 1990-03-15 Boehringer Mannheim Gmbh Phenylamide - verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel
US5166170A (en) * 1989-07-03 1992-11-24 Hoechst-Roussel Pharmaceuticals Incorporated 2-(aminoaryl) indoles and indolines as topical antiinflammatory agents for the treatment of skin disorders
US5068252A (en) * 1989-07-26 1991-11-26 Allergan, Inc. Methods of using phenylethenyl compounds having retinoid-like activity
US4992468A (en) * 1989-07-26 1991-02-12 Allergan, Inc. Phenylethenyl compounds having retinoid-like activity
US5399561A (en) * 1989-09-19 1995-03-21 Allergan, Inc. Acetylenes disubstituted with a phenyl or heteroaryl group and a 2-oxochromanyl, 2-oxothiochromanyl or 2-oxo-1,2,3,4-tetrahydro-quinolinyl group having retinoid-like biological activity
US5272156A (en) * 1989-09-19 1993-12-21 Allergan, Inc. Acetylenes disubstituted with a heteroaromatic group and a 2-substituted 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity
US5248777A (en) * 1989-09-19 1993-09-28 Allergan, Inc. Process and intermediates for preparing compounds having a disubstituted acetylene moiety and retinoic acid-like biological activity
US5183827A (en) * 1989-09-19 1993-02-02 Allergan, Inc. Acetylenes disubstituted with a heteroaromatic group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity
US5162546A (en) * 1989-09-19 1992-11-10 Allergan, Inc. Acetylenes disubstituted with a phenyl group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity
US5053523A (en) * 1989-09-19 1991-10-01 Allergan, Inc. Ethynyl-chroman compounds
US5264456A (en) * 1989-12-29 1993-11-23 Allergan, Inc. Acetylenes disubstituted with a furyl group and a substituted phenyl group having retinoid like activity
US5175185A (en) * 1989-12-29 1992-12-29 Allergan, Inc. Acetylenes disubstituted with a heteroaromatic group and a substituted phenyl group having retinoid like activity
US5013744B1 (en) * 1989-12-29 1994-09-20 Allegran Inc Acetylenes disubstituted with a pyridinyl group and a substituted phenyl group having retinoid like activity
US5006550A (en) * 1989-12-29 1991-04-09 Allergan, Inc. Chroman esters of phenols and benzoic acids having retinoid-like activity
US5202471A (en) * 1990-02-06 1993-04-13 Allergan, Inc. Alkyl, alkoxy and thioalkoxy substituted diphenyl acetylenes having retinoid like activity
US5254692A (en) * 1990-04-06 1993-10-19 Bayer Aktiengesellschaft 2,6-dialkyl-4-(benzothiazol- or benzoxazol-7-yl)-1,4-dihydropyridines
US5273739A (en) * 1990-12-07 1993-12-28 Jim Baral Composition and treatment for darkening hair color
ES2094350T3 (es) * 1991-02-13 1997-01-16 Allergan Inc Cromano y tiocromanos con sustituyentes de feniletinilo en la posicion 7 que tienen actividad biologica de tipo retinoide.
CA2105379A1 (en) * 1991-03-26 1992-09-27 Roshantha A. S. Chandraratna Chromans and thiochromans with heteroarylethynyl substituents at the 7-position having retinoid-like biological activity
US5134159A (en) * 1991-03-26 1992-07-28 Allergan, Inc. 7-chromanyl esters of phenols and benzoic acids having retinoid-like activity
US5869067A (en) * 1991-05-15 1999-02-09 Centre International De Recherches Dermatologiques Galderma (Cird Galderma) Bi-aromatic compounds and pharmaceutical and cosmetic compositions
FR2677020B1 (fr) * 1991-05-31 1993-08-27 Cird Galderma Composes derives de benzimidazole, leur procede de preparation et leur utilisation dans les domaines therapeutique et cosmetique.
WO1993016067A1 (en) * 1992-02-11 1993-08-19 Allergan, Inc. Heteroaryl substituted phenylethenyl compounds having retinoid-like biological activity
US5326898A (en) * 1992-02-11 1994-07-05 Allergan, Inc. Substituted phenylethenyl compounds having retinoid-like biological activity
US5324840A (en) * 1992-06-11 1994-06-28 Allergan, Inc. Method of treatment with compounds having retinoid-like activity and reduced skin toxicity and lacking teratogenic effects
EP0595150B1 (de) * 1992-10-29 1996-07-31 Hoechst Aktiengesellschaft Verfahren zur Herstellung von aromatischen Brommethyl-Verbindungen
US5455265A (en) * 1993-02-11 1995-10-03 Allergan, Inc. Method of treatment with compounds having selective agonist-like activity on RXR retinoid receptors
US6172115B1 (en) 1993-02-11 2001-01-09 Allergan Sales, Inc. Method for preventing onset of restenosis after angioplasty employing an RXR-specific retinoid
US5399586A (en) * 1993-03-11 1995-03-21 Allergan, Inc. Treatment of mammals afflicted with tumors with compounds having RXR retinoid receptor agonist activity
US5344959A (en) * 1993-05-18 1994-09-06 Allergan, Inc. Tetrahydronaphthyl and cyclopropyl substituted 1,3-butadienes having retinoid-like activity
CA2117413C (en) * 1993-07-30 2006-11-21 Neil Geach Herbicidal isoxazole-4-yl-methanone derivatives
GB9317949D0 (en) * 1993-08-28 1993-10-13 Stevens Malcolm F G Benzothiazole compounds
US5874431A (en) * 1993-08-28 1999-02-23 Cancer Research Campaign Technology Limited Benzazole compounds
US5475022A (en) * 1993-10-18 1995-12-12 Allergan, Inc. Phenyl or heteroaryl and tetrahydronaphthyl substituted diene compounds having retinoid like biological activity
US5426118A (en) * 1993-12-30 1995-06-20 Allergan, Inc. [4-(1,2-epoxycyclohexanyl)but-3-en-1-ynyl]aromatic and heteroaromatic acids and derivatives having retinoid-like biological activity
US5451605A (en) * 1993-12-30 1995-09-19 Allergan, Inc. 1,2-epoxycyclohexanyl and bicyclic aromatic substituted ethyne compounds having retinoid-like biological activity
US5470999A (en) * 1993-12-30 1995-11-28 Allergan, Inc. Cyclohexene and bicyclic aromatic substituted ethyne compounds having retinoid-like biological activity
DE59509233D1 (de) * 1994-02-24 2001-06-13 Haarmann & Reimer Gmbh Kosmetische und dermatologische zubereitungen, enthaltend phenylen-1,4-bisbenzimidiazolesulfonsäuren
US5498755A (en) * 1994-08-23 1996-03-12 Chandraratna; Roshantha A. Disubstituted aryl and heteroaryl imines having retinoid-like biological activity
FR2728166A1 (fr) 1994-12-19 1996-06-21 Oreal Composition topique contenant un antagoniste de substance p
US5618931A (en) * 1994-12-29 1997-04-08 Allergan Acetylenes disubstituted with a 5 substituted dihydronaphthyl group and with an aryl or heteroaryl group having retinoid-like biological activity
US5489584A (en) * 1994-12-29 1996-02-06 Allergan, Inc. Acetylenes disubstituted with a 5-amino or substituted 5-amino substituted tetrahydronaphthyl group and with an aryl or heteroaryl group having retinoid-like biological activity
US5514825A (en) * 1994-12-29 1996-05-07 Allergan, Inc. Acetylenes disubstituted with a 5 substituted tetrahydronaphthyl group and with an aryl or heteroaryl group having retinoid-like biological activity
US5618943A (en) * 1994-12-29 1997-04-08 Allergan Acetylenes disubstituted with a 5 OXO substituted tetrahydronaphthyl group and with an aryl or heteroaryl group having retinoid-like biological activity
US5648514A (en) 1994-12-29 1997-07-15 Allergan Substituted acetylenes having retinoid-like biological activity
US5534641A (en) * 1994-12-29 1996-07-09 Allergan Acetylenes disubstituted with 2-tetrahydropyranoxyaryl and aryl or heteroaryl groups having retinoid-like biological activity
US5556996A (en) * 1994-12-29 1996-09-17 Allergan Oxiranyls disubstituted with a phenyl group and a substituted chromanyl or tetrahydroquinolinyl group having retinoid like activity
US5543534A (en) * 1994-12-29 1996-08-06 Allergan Acetylenes disubstituted with a 5 substituted tetrahydronaphthyl group and with an aryl or heteroaryl groups having retinoid-like biological activity
US5599967A (en) * 1994-12-29 1997-02-04 Allergan Acetylenes disubstituted with a 5 substituted tetrahydronaphthyl group and with an aryl of heteroaryl group having retinoid-like biological activity
FR2729854A1 (fr) 1995-01-26 1996-08-02 Oreal Utilisation du sulfate de dehydroepi-androsterone dans une composition cosmetique ou dermatologique
FR2731706B1 (fr) * 1995-03-14 1997-04-11 Cird Galderma Composes heterocycliques aromatiques, compositions pharmaceutiques et cosmetiques les contenant et utilisations
US6025388A (en) * 1995-04-26 2000-02-15 Allergan Sales, Inc. Method for inhibiting gene expression promoted by AP1 protein with RARβ selective retinoids and method for treatment of diseases and conditions with such retinoids
US5616712A (en) * 1995-05-16 1997-04-01 Allergan Acetylenes disubstituted with a phenyl or heteroaryl group and a 2-thio-1,2,3,4-tetrahdroquinolinyl, 2-alkylthio-3,4-dihydroquinolinyl or 2-alkoxy-3,4-dihydroquinolinyl group having retinoid-like biological activity
US5917082A (en) * 1995-06-06 1999-06-29 Allergan Sales, Inc. 2,4-pentadienoic acid derivatives having retinoid-like biological activity
US5675033A (en) * 1995-06-06 1997-10-07 Allergan 2,4-pentadienoic acid derivatives having retinoid-like biological activity
DE19532311A1 (de) * 1995-09-01 1997-03-06 Basf Ag Benzoylderivate
US5952345A (en) * 1995-09-01 1999-09-14 Allergan Sales, Inc. Synthesis and use of retinoid compounds having negative hormone and/or antagonist activities
US5958954A (en) * 1995-09-01 1999-09-28 Allergan Sales, Inc. Synthesis and use of retinoid compounds having negative hormone and/or antagonist activities
US6008204A (en) 1995-09-01 1999-12-28 Allergan Sales, Inc. Synthesis and use of retinoid compounds having negative hormone and/or antagonist activities
US6218128B1 (en) 1997-09-12 2001-04-17 Allergan Sales, Inc. Methods of identifying compounds having nuclear receptor negative hormone and/or antagonist activities
US6942980B1 (en) 1995-09-01 2005-09-13 Allergan, Inc. Methods of identifying compounds having nuclear receptor negative hormone and/or antagonist activities
AU7598596A (en) * 1995-11-01 1997-05-22 Allergan, Inc. Sulfides, sulfoxides and sulfones disubstituted with a tetrahydronaphthalenyl, chromanyl, thiochromanyl or tetrahydroquinolinyl and substituted phenyl or heteroaryl group, having retinoid-like biological activity
US5675024A (en) * 1995-11-22 1997-10-07 Allergan Aryl or heteroaryl amides of tetrahydronaphthalene, chroman, thiochroman and 1,2,3,4,-tetrahydroquinoline carboxylic acids, having an electron withdrawing substituent in the aromatic or heteroaromatic moiety, having retinoid-like biological activity
US5663357A (en) 1995-11-22 1997-09-02 Allergan Substituted heteroarylamides having retinoid-like biological activity
US5688957A (en) * 1995-12-29 1997-11-18 Allergan (3"-thioxacyclohex-1"-enyl)!-but-3'-ene-1'-ynyl!aryl and (3"-thioxacyclohex-1"-enyl)!-but-3'-ene-1'-ynyl!heteroaryl carboxylic acids and esters having retinoid-like biological activity
US5965606A (en) 1995-12-29 1999-10-12 Allergan Sales, Inc. Methods of treatment with compounds having RAR.sub.α receptor specific or selective activity
US20030219832A1 (en) * 1996-03-11 2003-11-27 Klein Elliott S. Synthesis and use of retinoid compounds having negative hormone and/or antagonist activities
CN1211361C (zh) * 1996-03-18 2005-07-20 卫材株式会社 含有稠环的羧酸衍生物
US5747542A (en) * 1996-06-21 1998-05-05 Allergan Oxo-substituted tetrahydronaphthalene derivatives having retinold and/or retinoid antagonist-like biological activity
US5741896A (en) 1996-06-21 1998-04-21 Allergan O- or S- substituted tetrahydronaphthalene derivatives having retinoid and/or retinoid antagonist-like biological activity
US5763635A (en) * 1996-06-21 1998-06-09 Allergan Tetrahydronaphthalene derivatives substituted in the 8 position with alkyhidene groups having retinoid and/or retinoid antagonist-like biological activity
US5723666A (en) * 1996-06-21 1998-03-03 Allergan Oxime substituted tetrahydronaphthalene derivatives having retinoid and/or retinoid antagonist-like biological activity
US5773594A (en) * 1996-06-21 1998-06-30 Allergan Alkyl or aryl substituted dihydronaphthalene derivatives having retinoid and/or retinoid antagonist-like biological activity
US5808124A (en) * 1996-06-21 1998-09-15 Allergan O- or S-substituted dihydronaphthalene derivatives having retinoid and/or retinoid antagonist-like biological activity
US6555690B2 (en) 1996-06-21 2003-04-29 Allergan, Inc. Alkyl or aryl substituted dihydronaphthalene derivatives having retinoid and/or retinoid antagonist-like biological activity
FR2750426B1 (fr) * 1996-06-28 1998-08-07 Cird Galderma Nouveaux composes biaryles heterocycliques et leur utilisation en medecine humaine ou veterinaire ainsi qu'en cosmetique
US6127415A (en) * 1996-07-08 2000-10-03 Galderma Research & Development, S.N.C. Apoptosis inducing adamantyl derivatives and their usage as anti-cancer agents
US6630496B1 (en) 1996-08-26 2003-10-07 Genetics Institute Llc Inhibitors of phospholipase enzymes
US5739338A (en) * 1996-11-05 1998-04-14 Allergan N-aryl substituted tetrahydroquinolines having retinoid agonist, retinoid antagonist or retinoid inverse agonist type biological activity
US5728846A (en) * 1996-12-12 1998-03-17 Allergan Benzo 1,2-g!-chrom-3-ene and benzo 1,2-g!-thiochrom-3-ene derivatives
US5760276A (en) * 1997-03-06 1998-06-02 Allergan Aryl-and heteroarylcyclohexenyl substituted alkenes having retinoid agonist, antagonist or inverse agonist type biological activity
US6037488A (en) 1997-04-19 2000-03-14 Allergan Sales, Inc. Trisubstituted phenyl derivatives having retinoid agonist, antagonist or inverse agonist type biological activity
US5919970A (en) 1997-04-24 1999-07-06 Allergan Sales, Inc. Substituted diaryl or diheteroaryl methanes, ethers and amines having retinoid agonist, antagonist or inverse agonist type biological activity
US6828344B1 (en) 1998-02-25 2004-12-07 Genetics Institute, Llc Inhibitors of phospholipase enzymes
US6916841B2 (en) * 1998-02-25 2005-07-12 Genetics Institute, Llc Inhibitors of phospholipase enzymes
US6500853B1 (en) 1998-02-28 2002-12-31 Genetics Institute, Llc Inhibitors of phospholipase enzymes
IL139317A0 (en) * 1998-05-05 2001-11-25 Byk Gulden Lomberg Chem Fab Benzimdazole and benzoxazole derivatives and pharmaceutical compositions contining the same
PT1194425E (pt) 1999-06-23 2005-10-31 Aventis Pharma Gmbh Benzimidazoles substituidos
US6252090B1 (en) 2000-08-29 2001-06-26 Allergan Sales, Inc. Compounds having activity as inhibitors of cytochrome P450RAI
US6380256B1 (en) * 2000-08-29 2002-04-30 Allergan Sales, Inc. Compounds having activity as inhibitors of cytochrome P450RAI
US6369225B1 (en) 2000-08-29 2002-04-09 Allergan Sales, Inc. Compounds having activity as inhibitors of cytochrome P450RAI
US6313107B1 (en) 2000-08-29 2001-11-06 Allergan Sales, Inc. Methods of providing and using compounds having activity as inhibitors of cytochrome P450RAI
EP2335700A1 (en) * 2001-07-25 2011-06-22 Boehringer Ingelheim (Canada) Ltd. Hepatitis C virus polymerase inhibitors with a heterobicylic structure
JP4637481B2 (ja) * 2001-10-19 2011-02-23 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド Ｃｄｓ１／ｃｈｋ２阻害剤および癌治療における化学療法または放射線療法の補助剤としての２−フェニルベンズイミダゾールおよびイミダゾ−［４，５］−ピリジン
FR2833165B1 (fr) * 2001-12-10 2004-07-30 Oreal Utilisation de derives hydroxyles de benzofurane pour inhiber la glycation, composition les comprenant et procede de traitement.
US7098231B2 (en) 2003-01-22 2006-08-29 Boehringer Ingelheim International Gmbh Viral polymerase inhibitors
US7223785B2 (en) 2003-01-22 2007-05-29 Boehringer Ingelheim International Gmbh Viral polymerase inhibitors
ATE363905T1 (de) * 2003-04-17 2007-06-15 Janssen Pharmaceutica Nv 2-phenyl-benzimidazol und 2-phenyl-imidazo-4,5)- pyridin-derivate als checkpoint-kinase-cds1 (chk2)-hemmer zur behandlung von krebs
SG184700A1 (en) 2004-02-20 2012-10-30 Boehringer Ingelheim Int Viral polymerase inhibitors
US7250427B2 (en) * 2004-06-30 2007-07-31 Janssen Pharmaceutica, N.V. Aryl-substituted benzimidazole and imidazopyridine ethers
US8158136B2 (en) 2004-08-18 2012-04-17 L'oréal Emulsification system for use in cosmetics
CA2578529A1 (en) 2004-08-18 2006-02-23 Ace Aps Cosmetic and pharmaceutical compositions comprising ace inhibitors and/or angiotensin ii receptor antagonists
WO2006037922A1 (fr) * 2004-10-04 2006-04-13 L'oreal Composition cosmetique et/ou dermatologique pour peaux sensibles
KR20060087386A (ko) * 2005-01-28 2006-08-02 주식회사 대웅제약 신규 벤조이미다졸 유도체 및 이를 함유하는 약제학적조성물
FR2889057B1 (fr) * 2005-08-01 2008-07-18 Oreal Composition cosmetique et/ou dermatologique pour la prevention et/ou le traitement des peaux sensibles ou seches
EP1915378A4 (en) 2005-08-12 2009-07-22 Boehringer Ingelheim Int VIRUS POLYMERASE INHIBITORS
FR2889808B1 (fr) 2005-08-17 2011-07-22 Oreal Utilisation de l'acide 8-hexadecene-1,16-dicarboxylique comme agent de soin destine a favoriser la cohesion de la couche cornee
US7816348B2 (en) * 2006-02-03 2010-10-19 Boehringer Ingelheim International Gmbh Viral polymerase inhibitors
JP2011512164A (ja) 2007-02-20 2011-04-21 ガルデルマ・リサーチ・アンド・デヴェロップメント 皮膚内への治療物質の送達方法
FR2912651A1 (fr) 2007-02-21 2008-08-22 Oreal Emulsion e/h pour le soin de la peau.
FR2912917B1 (fr) 2007-02-26 2012-05-18 Oreal Milieu conditionne et ses utilisations
FR2918886B1 (fr) 2007-07-17 2010-01-08 Oreal Utilisation d'au moins un extrait bacterien cultive sur eau thermale pour le traitement des peaux, muqueuses et cuirs chevelus sensibles
FR2919501B1 (fr) * 2007-08-02 2010-12-31 Oreal Utilisation d'hesperidine ou de l'un de ses derives pour la prevention et/ou le traitement des peaux relachees
JP2010535156A (ja) * 2007-08-03 2010-11-18 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ウイルスポリメラーゼ阻害剤
JP2010535155A (ja) * 2007-08-03 2010-11-18 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ウイルスポリメラーゼ阻害剤
FR2920304B1 (fr) 2007-09-04 2010-06-25 Oreal Utilisation cosmetique de lysat bifidobacterium species pour le traitement de la secheresse.
CA2697735C (en) * 2007-09-04 2014-02-18 L'oreal Use of a combination of hesperidin and of a microorganism for influencing the barrier function of the skin
FR2920305B1 (fr) 2007-09-04 2010-07-30 Oreal Utilisation d'un lysat de bifidobacterium species pour le traitement de peaux sensibles.
EA201000948A1 (ru) 2007-12-19 2011-02-28 Бёрингер Ингельхайм Интернациональ Гмбх Ингибиторы вирусной полимеразы
FR2928542B1 (fr) 2008-03-13 2011-12-09 Oreal Procede de maquillage des levres
FR2940907B1 (fr) 2009-01-15 2011-03-04 Oreal Composition cosmetique ou dermatologique, comprenant un retinoide, un compose non phosphate a base d'adenosine et un polymere semi-cristallin
FR2942719B1 (fr) 2009-03-04 2011-08-19 Oreal Utilisation de microorganismes probiotiques pour limiter les irritations cutanees
WO2011010075A1 (fr) 2009-07-24 2011-01-27 L'oreal Utilisation d'un derive d'acide jasmonique en tant qu'agent apaisant
FR2953716B1 (fr) 2009-12-16 2015-03-27 Oreal Kit de formulation d'un produit cosmetique
FR2968952A1 (fr) 2010-12-17 2012-06-22 Oreal Ester d'acide amine n-acyle a titre d'agent apaisant
FR2981272A1 (fr) 2011-10-14 2013-04-19 Inneov Lab Utilisation d'une composition orale comprenant un melange d'au moins un polyphenol, de zinc, et de vitamine c.
ES2908095T3 (es) 2012-04-11 2022-04-27 Oreal Lámina cosmética autosoportada
FR2996135A1 (fr) 2012-09-28 2014-04-04 Inneov Lab Composition orale pour renforcer la tolerance cutanee suite a une administration topique d'un compose retinoide.
EP2789369B1 (en) 2013-04-14 2018-06-06 Symrise AG A composition for lightening skin and hair
EP2842607B1 (en) 2013-09-02 2018-05-30 Symrise AG A skin and/or hair whitening mixture
EP3721944A1 (en) 2013-09-22 2020-10-14 Cutech S.R.L. Extracts of halimione portulacoides and their application
EP2853254B1 (en) 2013-09-26 2017-11-08 Symrise AG A composition for lightening skin and/or hair
EP2859883B1 (en) 2013-10-13 2019-05-15 Symrise AG Active mixtures comprising acylated oligopeptides and troxerutin
EP3062766A1 (en) 2013-10-29 2016-09-07 L'Oreal, S.A. Use of mono ornithine ketoglutarate (mokg)
US20170114019A1 (en) 2014-06-04 2017-04-27 Haro Pharmaceutical Inc. 18-20 member bi-polycyclic compounds
EP2979682B1 (en) 2014-07-30 2018-09-05 Symrise AG A fragrance composition
EP3023090B1 (en) 2014-11-21 2019-08-07 Symrise AG Compositions
EP3045161A1 (en) 2015-01-18 2016-07-20 Symrise AG Active compositions comprising 1,2-hexanediol and 1,2-octanediol
ES2933563T3 (es) 2015-04-16 2023-02-10 Symrise Ag Uso de una composición de liposoma
US10391071B2 (en) 2015-04-28 2019-08-27 Cutech Srl Compositions comprising valerian extracts
EP3097905B1 (en) 2015-05-28 2020-11-04 Symrise AG Cosmetic compositions
EP3108941B1 (en) 2015-06-23 2018-05-09 Symrise AG Compositions comprising polyalkylene glycol derivatives
WO2017041834A1 (en) 2015-09-08 2017-03-16 Symrise Ag Fragrance mixtures
CN108366932B (zh) 2015-10-28 2022-03-15 西姆莱斯股份公司 用于抑制或遮蔽鱼腥味的方法
CN108699019B (zh) * 2015-11-11 2022-05-10 华纳巴布科克绿色化学学院有限公司 用于治疗中枢神经系统和其他疾病的苯并呋喃衍生物
CN108472220B (zh) 2015-11-15 2022-06-17 西姆莱斯股份公司 减少皮肤刺痛感受
WO2017097434A1 (en) 2015-12-06 2017-06-15 Symrise Ag A fragrance composition
JP2019510062A (ja) 2016-03-30 2019-04-11 シムライズ アーゲー 活性成分混合物
EP4603149A2 (en) 2016-08-20 2025-08-20 Symrise AG A preservative mixture
CN110149795B (zh) 2016-12-02 2023-10-03 西姆莱斯股份公司 化妆品混合物
FR3061002B1 (fr) 2016-12-23 2019-05-24 L'oreal Composition comprenant de l’acide hydroxyethylpiperazine ethane sulfonique et au moins un alkylpolyglucoside
IT201700090929A1 (it) 2017-08-07 2019-02-07 Cutech S R L Usi cosmetici e medici di estratti del fungo Coprinus comatus per la regolazione dell’unità pilo sebacea.
DE202017007679U1 (de) 2017-08-09 2024-03-15 Symrise Ag 1,2-Alkandiole
US20210085579A1 (en) 2017-08-09 2021-03-25 Symrise Ag 1,2-alkanediols and a process for their production
US12016944B2 (en) 2018-03-08 2024-06-25 Symrise Ag Mixtures comprising a protein extract for the treatment of human skin and/or hair
MX2021003248A (es) 2018-09-20 2021-05-12 Symrise Ag Composiciones que comprenden 1,2-pentanodiol.
AU2019434303B2 (en) 2019-03-12 2024-11-14 Symrise Ag An antimicrobial mixture
EP4438065A3 (en) 2020-12-09 2025-01-01 Symrise AG A mixture comprising 1,2-alkanediols
FR3126311B1 (fr) 2021-08-27 2024-12-20 Oreal Procede cosmetique non therapeutique pour reduire les rides sur une surface de la peau, kit pour la mise en œuvre du procede, et procede d’utilisation d’un kit
WO2023286879A2 (en) 2021-07-16 2023-01-19 L'oreal A non-therapeutic cosmetic method for reducing wrinkles on a skin surface, a kit for implementing the method, and a method of using a kit

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE676103C (de) * 1933-03-31 1939-05-25 I G Farbenindustrie Akt Ges Strahlungsschutzmittel
GB846737A (en) * 1956-04-19 1960-08-31 Merck & Co Inc 3-substituted 4-hydroxybenzoic acids and their preparation
CH483276A (de) * 1959-09-23 1969-12-31 Ciba Geigy Verwendung von 2-Phenyl-benzazolen als Schutzmittel vor ultravioletter Strahlung ausserhalb der Textilindustrie
GB1067575A (en) * 1963-06-28 1967-05-03 Jacques Logeais Soc D Expl Des Therapeutic compositions containing phloroglucinol derivatives, new derivatives of phloroglucinol and process for preparing the same
IL23847A (en) * 1964-08-07 1969-02-27 Merck & Co Inc Benzimidazoles useful as antifungals
FR1494097A (fr) * 1965-04-06 1967-09-08 Ciba Geigy Dérivés du 2-phénylbenzoxazol servant d'agents d'absorption des rayons ultraviolets pour des produits cosmétiques
DE1642090A1 (de) * 1966-05-20 1971-05-19 Merck Patent Gmbh UV-Lichtschutzmittel fuer kosmetische Zwecke
CH495756A (de) * 1968-06-11 1970-09-15 Ciba Geigy Verwendung von neuen, Alkylsulfonsäuregruppen enthaltenden 2-Phenylbenzoxazol-Derivaten als Ultraviolett-Absorber für kosmetische Zwecke
US3551443A (en) * 1968-10-30 1970-12-29 Ciba Ltd 2-phenylbenzoxazole derivatives
CH523909A (de) * 1969-01-09 1972-06-15 Ciba Geigy Ag Verfahren zur Herstellung heterocyclischer, Aethylendoppelbindungen enthaltender Verbindungen und deren Verwendung als optische Aufhellmittel ausserhalb der Textilindustrie
CH516339A (de) * 1969-03-03 1971-12-15 Ciba Geigy Ag Verwendung von Azolverbindungen als Antioxydantien
DE2419728A1 (de) * 1974-04-24 1975-11-20 Hoechst Ag Kosmetisches lichtschutzmittel
LU71012A1 (en, 2012) * 1974-09-26 1976-08-19
DE2619547A1 (de) * 1976-05-04 1977-11-24 Dynamit Nobel Ag Verfahren zur herstellung von 2-aryl- benzoxazolen und 2-aryl-benzthiazolen
GB1584296A (en) * 1976-12-07 1981-02-11 Kanebo Ltd 2-substituted benzimidazole compounds
US4192880A (en) * 1977-04-07 1980-03-11 Kanebo, Ltd. 2-Substituted benzimidazole compounds
DE3003540A1 (de) * 1980-01-31 1981-08-06 Bayer Ag, 5090 Leverkusen Benzoxazolylstilbene, verfahren zu deren herstellung und deren verwendung als optische aufheller
DD150059A1 (de) * 1980-04-07 1981-08-12 Horst Hartmann Verfahren zur herstellung von hydroxyarylazolen
DE3224512A1 (de) * 1982-07-01 1984-01-05 Dr. Karl Thomae Gmbh, 7950 Biberach Neue imidazolderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel
US4456618A (en) * 1982-10-15 1984-06-26 Sri International Naphthenic and heterocyclic retinoic acid analogues
DE3346575A1 (de) * 1983-12-23 1985-07-04 Dr. Karl Thomae Gmbh, 7950 Biberach Neue benzimidazole, ihre herstellung und diese verbindungen enthaltende arzneimittel
CA1281325C (en) * 1984-06-20 1991-03-12 Patrice C. Belanger Benzofuran derivatives
DE3522230A1 (de) * 1985-06-21 1987-01-02 Thomae Gmbh Dr K Neue 2-arylimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
DE3528032A1 (de) * 1985-08-05 1987-02-05 Hoechst Ag Verfahren zur herstellung 2-substituierter benzthiazole

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
HETEROCTCLES=1977 *
INDIAN J.CHEM=1980 *

Also Published As

Publication number Publication date
IT1209663B (it) 1989-08-30
DE3546907C2 (de) 1998-06-10
AU578310B2 (en) 1988-10-20
NL8502557A (nl) 1986-04-16
GB8722903D0 (en) 1987-11-04
CH665841A5 (fr) 1988-06-15
CH675241A5 (en, 2012) 1990-09-14
GB2197320A (en) 1988-05-18
GB2164648A (en) 1986-03-26
PT81132B (pt) 1988-04-21
SE502470C2 (sv) 1995-10-23
SE8504291L (sv) 1986-03-20
GB2164648B (en) 1989-06-01
DE3533308A1 (de) 1986-03-27
JPS6185360A (ja) 1986-04-30
AT401514B (de) 1996-09-25
SE8504291D0 (sv) 1985-09-16
AR243504A1 (es) 1993-08-31
ZA857158B (en) 1986-05-28
GR852270B (en, 2012) 1986-01-21
SE461466B (sv) 1990-02-19
FR2570377A1 (fr) 1986-03-21
NL192878C (nl) 1998-04-02
DK423285D0 (da) 1985-09-18
AU593838B2 (en) 1990-02-22
ES547750A0 (es) 1986-07-16
MX166783B (es) 1993-02-04
GB2197320B (en) 1989-06-01
ATA271885A (de) 1992-07-15
AT395714B (de) 1993-02-25
PT81132A (en) 1985-10-01
IT8522180A0 (it) 1985-09-18
AU4755985A (en) 1986-03-27
ATA42192A (de) 1996-02-15
US4740519A (en) 1988-04-26
DK423285A (da) 1986-03-20
CA1256804A (fr) 1989-07-04
BE904421A (fr) 1986-06-30
US4920140A (en) 1990-04-24
DK169475B1 (da) 1994-11-07
US5059621A (en) 1991-10-22
DE3533308C2 (de) 1996-09-26
BE903254A (fr) 1986-03-18
LU85544A1 (fr) 1986-04-03
SE8800949D0 (sv) 1988-03-16
AU6299586A (en) 1987-01-08
GB8727803D0 (en) 1987-12-31
NL192878B (nl) 1997-12-01
FR2570377B1 (fr) 1987-11-13
ES8608487A1 (es) 1986-07-16
GB8523203D0 (en) 1985-10-23
CA1256862A (fr) 1989-07-04
SE8800949L (sv) 1988-03-16

Similar Documents

Publication Publication Date Title
JPH0784437B2 (ja) 複素環レチノイド
JP2614606B2 (ja) 多環式芳香族誘導体、その製造方法並びに医薬および化粧領域における適用
JP2548176B2 (ja) ベンゾピラニルおよびベンゾチオピラニルベンゼン化合物、その製法並びに化粧品とひと・動物薬
DK172070B1 (da) Benzonaphthalen-derivater, fremgangsmåde til deres fremstilling og deres anvendelse samt framaceutiske og kosmetiske præparater deraf
NL193855C (nl) Naftaleenderivaten alsmede farmaceutische en cosmetische preparaten, die deze derivaten bevatten.
JP2618225B2 (ja) 新規ベンゾノルボルネン誘導体、その製法およびそれを含む医薬または化粧組成物
DE69524428T2 (de) Dihydrobenzofuran und verwandte verbindungen als entzündungshemmende mittel
JP2579339B2 (ja) 多環複素環誘導体、その製法および人・動物医薬
DK172328B1 (da) Bicycliske aromatiske forbindelser, fremgangsmåde til deres fremstilling og kosmetiske og farmaceutiske præparater deraf
JP3009622B2 (ja) 複素環式芳香族化合物とそれらを含有する製薬用および化粧品用の組成物およびその使用
DE3711546C2 (de) Aromatische Verbindungen, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische und kosmetische Zubereitungen
JP3566210B2 (ja) ジアリールセレン化物化合物、並びにヒト又は動物の医薬及び化粧品における使用
KR19990067642A (ko) 항염증제로서 유용한 황 함유의 디- tert-부틸페놀 화합물
JP2664660B2 (ja) 新規な芳香族ジベンゾフラン誘導体類およびそれらを含有する製薬用および化粧品用組成物
JP2791695B2 (ja) 新規ベンゾフラン化合物、その製造法、それを含有する組成物及び該組成物の使用方法
US5428052A (en) Aromatic heterocyclic derivatives and their therapeutic and cosmetic use
US4621091A (en) 3-hydroxybenzo[b]thiophene-2-sulfide derivatives compositions, and method of use therefor
US5260295A (en) Aromatic heterocyclic derivatives and their therapeutic and cosmetic use
JPS61194040A (ja) 不飽和脂環式誘導体、その治療および化粧用途

Legal Events

Date Code Title Description
R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees