JPH0713023B2 - 長時間にわたって薬剤の放出を維持・調節するための薬剤組成物 - Google Patents

長時間にわたって薬剤の放出を維持・調節するための薬剤組成物

Info

Publication number
JPH0713023B2
JPH0713023B2 JP63238626A JP23862688A JPH0713023B2 JP H0713023 B2 JPH0713023 B2 JP H0713023B2 JP 63238626 A JP63238626 A JP 63238626A JP 23862688 A JP23862688 A JP 23862688A JP H0713023 B2 JPH0713023 B2 JP H0713023B2
Authority
JP
Japan
Prior art keywords
release
maintaining
long period
water
drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP63238626A
Other languages
English (en)
Japanese (ja)
Other versions
JPH01121222A (ja
Inventor
オルソリニ ピエロ
イブ モーベルネ ロラン
デーゲンギ ロマノ
Original Assignee
ドゥビオファルム ソシエテ アノニム
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ドゥビオファルム ソシエテ アノニム filed Critical ドゥビオファルム ソシエテ アノニム
Publication of JPH01121222A publication Critical patent/JPH01121222A/ja
Publication of JPH0713023B2 publication Critical patent/JPH0713023B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
JP63238626A 1987-09-21 1988-09-21 長時間にわたって薬剤の放出を維持・調節するための薬剤組成物 Expired - Lifetime JPH0713023B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8722134 1987-09-21
GB8722134A GB2209937B (en) 1987-09-21 1987-09-21 Water insoluble polypeptides

Publications (2)

Publication Number Publication Date
JPH01121222A JPH01121222A (ja) 1989-05-12
JPH0713023B2 true JPH0713023B2 (ja) 1995-02-15

Family

ID=10624108

Family Applications (1)

Application Number Title Priority Date Filing Date
JP63238626A Expired - Lifetime JPH0713023B2 (ja) 1987-09-21 1988-09-21 長時間にわたって薬剤の放出を維持・調節するための薬剤組成物

Country Status (23)

Country Link
US (2) US5192741A ( )
JP (1) JPH0713023B2 ( )
AT (1) AT397035B ( )
AU (1) AU611944B2 ( )
BE (1) BE1001685A5 ( )
CA (1) CA1326438C ( )
CH (1) CH675968A5 ( )
DE (2) DE3822459C2 ( )
DK (1) DK175311B1 ( )
ES (1) ES2009346A6 ( )
FI (1) FI96919C ( )
FR (1) FR2620621B1 ( )
GB (1) GB2209937B ( )
GR (1) GR1002244B ( )
IE (1) IE60608B1 ( )
IL (1) IL87790A ( )
IT (1) IT1225148B ( )
LU (1) LU87340A1 ( )
NL (1) NL193818C ( )
NO (2) NO178604C ( )
PT (1) PT88557B ( )
SE (1) SE503406C2 ( )
ZA (1) ZA886827B ( )

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US5192741A (en) 1993-03-09
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US5776885A (en) 1998-07-07
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IT1225148B (it) 1990-11-02
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LU87340A1 (fr) 1989-04-06
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PT88557B (pt) 1992-11-30
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