SG11201407678YA - Somatostatin receptor agonist formulations - Google Patents
Somatostatin receptor agonist formulationsInfo
- Publication number
- SG11201407678YA SG11201407678YA SG11201407678YA SG11201407678YA SG11201407678YA SG 11201407678Y A SG11201407678Y A SG 11201407678YA SG 11201407678Y A SG11201407678Y A SG 11201407678YA SG 11201407678Y A SG11201407678Y A SG 11201407678YA SG 11201407678Y A SG11201407678Y A SG 11201407678YA
- Authority
- SG
- Singapore
- Prior art keywords
- international
- solvegatan
- camurus
- ideon
- lund
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/31—Somatostatins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1274—Non-vesicle bilayer structures, e.g. liquid crystals, tubules, cubic phases, cochleates; Sponge phases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
Abstract
(12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 28 November 2013 (28.11.2013) WIPOIPCT (10) International Publication Number WO 2013/174978 A1 (51) International Patent Classification: A61K9/00 (2006.01) A61K 47/10 (2006.01) A61K 9/127 (2006.01) A61K 47/14 (2006.01) A61K38/00 (2006.01) A61K 47/24 (2006.01) (21) International Application Number: (22) International Filing Date: (25) Filing Language: (26) Publication Language: PCT/EP2013/060739 24 May 2013 (24.05.2013) English (30) Priority Data: PCT/EP2012/059917 25 May 2012 (25.05.2012) 61/730,613 28 November 2012 (28.11.2012) English EP US (71) Applicant: CAMURUS AB [SE/SE]; Ideon, Gamma 1, Solvegatan 41, SE-223 70 Lund (SE). (72) Inventors: NISTOR, Catalin; Camurus AB, Ideon, Gamma 1, Solvegatan 41, SE-223 70 Lund (SE). JOHNS- SON, Markus; Camurus AB, Ideon, Gamma 1, Solvegatan 41, SE-223 70 Lund (SE). TIBERG, Fredrik; Camurus AB, Ideon, Gamma 1, Solvegatan 41, SE-223 70 Lund (SE). (74) Agent: DEHNS; St Bride's House, 10 Salisbury Square, London EC4Y 8JD (GB). (81) Designated States (unless otherwise indicated, for every kind of national protection available)'. AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available)'. ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) 00 l> o\ •t l> i-H cn i-H o CJ o & (54) Title: SOMATOSTATIN RECEPTOR AGONIST FORMULATIONS (57) Abstract: The present invention relates to compositions forming a low viscosity mixture of: a) 20-50 wt.% of at least one diacyl glycerol; b) 20-54 wt.% of at least one phosphatidyl choline (PC); c) 5-15wt.% of at least one biocompatible, organic mono-alcohol - ic solvent; d) 1 to 20 wt.% polar solvent e) 5 to 150 mg/ml of at least one peptide somatostatin receptor agonist comprising pasireotide; f) optionally at least one antioxidant; wherein the ratio of components a:b is in the range 40:60 to 54:46; wherein the pre-formulation forms, or is capable of forming, at least one liquid crystalline phase structure upon contact with excess aqueous flu id. The invention further relates to methods of treatment comprising administration of such compositions, and to pre-filled adminis - tration devices and kits containing the formulations.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/EP2012/059917 WO2012160213A1 (en) | 2011-05-25 | 2012-05-25 | Controlled release peptide formulations |
US201261730613P | 2012-11-28 | 2012-11-28 | |
PCT/EP2013/060739 WO2013174978A1 (en) | 2012-05-25 | 2013-05-24 | Somatostatin receptor agonist formulations |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201407678YA true SG11201407678YA (en) | 2014-12-30 |
Family
ID=49623188
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201407678YA SG11201407678YA (en) | 2012-05-25 | 2013-05-24 | Somatostatin receptor agonist formulations |
Country Status (23)
Country | Link |
---|---|
US (2) | US11672843B2 (en) |
JP (1) | JP6374380B2 (en) |
KR (1) | KR102139080B1 (en) |
CN (1) | CN104487050B (en) |
AU (1) | AU2013265210B2 (en) |
BR (1) | BR112014029425A2 (en) |
CA (1) | CA2874367C (en) |
CL (1) | CL2014003185A1 (en) |
CO (1) | CO7160067A2 (en) |
DK (1) | DK2861209T3 (en) |
EA (1) | EA035495B1 (en) |
ES (1) | ES2834318T3 (en) |
HK (1) | HK1207985A1 (en) |
IL (1) | IL235740A0 (en) |
IN (1) | IN2014DN09831A (en) |
MA (1) | MA37672A1 (en) |
MX (1) | MX350964B (en) |
NZ (1) | NZ702028A (en) |
PE (1) | PE20150195A1 (en) |
PH (1) | PH12014502614A1 (en) |
SG (1) | SG11201407678YA (en) |
TN (1) | TN2014000483A1 (en) |
WO (1) | WO2013174978A1 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2390331C2 (en) * | 2004-06-04 | 2010-05-27 | Камурус Аб | Liquid drug reservoirs |
US11433120B2 (en) * | 2011-05-25 | 2022-09-06 | Camurus Ab | Controlled release peptide formulations |
WO2018060213A1 (en) * | 2016-09-27 | 2018-04-05 | Camurus Ab | Formulations containing a somatostatin receptor agonist |
CN113018248B (en) * | 2019-12-23 | 2022-07-22 | 南京清普生物科技有限公司 | Sustained-release drug delivery system |
CN114240934B (en) * | 2022-02-21 | 2022-05-10 | 深圳大学 | Image data analysis method and system based on acromegaly |
Family Cites Families (58)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2209937B (en) | 1987-09-21 | 1991-07-03 | Depiopharm S A | Water insoluble polypeptides |
US4938763B1 (en) | 1988-10-03 | 1995-07-04 | Atrix Lab Inc | Biodegradable in-situ forming implants and method of producing the same |
US5340802A (en) | 1989-06-30 | 1994-08-23 | Abbott Laboratories | Peptide analog type-B CCK receptor ligands |
CA2535463A1 (en) | 1989-07-07 | 1991-01-08 | Novartis Ag | Octreotide-pamoate and its use in sustained release formulations of water soluble peptides |
PH30995A (en) | 1989-07-07 | 1997-12-23 | Novartis Inc | Sustained release formulations of water soluble peptides. |
MY107937A (en) | 1990-02-13 | 1996-06-29 | Takeda Chemical Industries Ltd | Prolonged release microcapsules. |
WO1993006921A1 (en) | 1991-10-04 | 1993-04-15 | Gs Biochem Ab | Particles, method of preparing said particles and uses thereof |
ATE182278T1 (en) | 1991-10-04 | 1999-08-15 | Gs Dev Ab | PARTICLES, METHOD FOR PRODUCING THE PARTICLES AND THEIR USE |
US6228383B1 (en) | 1994-03-03 | 2001-05-08 | Gs Development Ab | Use of fatty acid esters as bioadhesive substances |
CA2186750C (en) | 1994-03-30 | 2008-08-05 | Jens Hansen | Use of fatty acid esters as bioadhesive substances |
SE518578C2 (en) | 1994-06-15 | 2002-10-29 | Gs Dev Ab | Lipid-based composition |
FR2725369B1 (en) | 1994-10-07 | 1997-01-03 | Oreal | COSMETIC OR DERMATOLOGICAL COMPOSITION CONSISTING OF AN OIL IN WATER EMULSION BASED ON OIL CELLS PROVIDED WITH A LAMELLAR LIQUID CRYSTAL COATING |
AU702030B2 (en) | 1995-10-12 | 1999-02-11 | Gs Development Ab | A pharmaceutical composition for administration of an active substance to or through a skin or mucosal surface |
US6458924B2 (en) | 1996-08-30 | 2002-10-01 | Novo Nordisk A/S | Derivatives of GLP-1 analogs |
EP0839525B1 (en) | 1996-10-31 | 2004-08-04 | Takeda Chemical Industries, Ltd. | Sustained-release preparation |
JP2001524958A (en) | 1997-04-17 | 2001-12-04 | ジーエス ディベロップメント アクティエボラーグ | A novel liquid crystal based bioadhesive drug delivery system |
US6638621B2 (en) | 2000-08-16 | 2003-10-28 | Lyotropic Therapeutics, Inc. | Coated particles, methods of making and using |
US20040018241A1 (en) | 1997-09-26 | 2004-01-29 | Noven Pharmaceuticals, Inc. | Bioadhesive compositions and methods for topical administration of active agents |
US6320017B1 (en) | 1997-12-23 | 2001-11-20 | Inex Pharmaceuticals Corp. | Polyamide oligomers |
BE1011899A6 (en) | 1998-04-30 | 2000-02-01 | Ucb Sa | PHARMACEUTICAL USE gelling. |
SI1140148T1 (en) | 1998-12-22 | 2006-04-30 | Lilly Co Eli | Shelf-stable solution formulation of glucagon-like peptide-1 |
US6011067A (en) | 1999-06-11 | 2000-01-04 | Thione International, Inc. | Antioxidant composition for the treatment of psoriasis and related diseases |
GB0018891D0 (en) * | 2000-08-01 | 2000-09-20 | Novartis Ag | Organic compounds |
US20020153508A1 (en) | 2000-06-29 | 2002-10-24 | Lynch Matthew Lawrence | Cubic liquid crystalline compositions and methods for their preparation |
US7008646B2 (en) | 2001-02-20 | 2006-03-07 | Patrick Thomas Spicer | Cubic liquid crystalline compositions and methods for their preparation |
US6936187B2 (en) | 2001-02-21 | 2005-08-30 | Matthew Lawrence Lynch | Functionalized cubic liquid crystalline phase materials and methods for their preparation and use |
US6656385B2 (en) | 2001-02-21 | 2003-12-02 | The Procter & Gamble Company | Functionalized cubic liquid crystalline phase materials and methods for their preparation and use |
CA2451432A1 (en) | 2001-06-23 | 2003-01-03 | Lyotropic Therapeutics, Inc. | Particles with improved solubilization capacity |
DK1412384T3 (en) | 2001-06-28 | 2008-04-28 | Novo Nordisk As | Stable formulation of modified GLP-1 |
AU2003201998C1 (en) | 2002-01-10 | 2012-10-25 | Imperial Innovations Limited | Modification of feeding behavior |
US7622118B2 (en) | 2002-07-15 | 2009-11-24 | Board Of Regents, The University Of Texas System | Cancer treatment methods using selected antibodies to aminophospholipids |
US7731947B2 (en) | 2003-11-17 | 2010-06-08 | Intarcia Therapeutics, Inc. | Composition and dosage form comprising an interferon particle formulation and suspending vehicle |
GB0305941D0 (en) | 2003-03-14 | 2003-04-23 | Camurus Ab | Composition |
GB0307777D0 (en) | 2003-04-04 | 2003-05-07 | Medical Res Council | Conjugate compounds |
ATE411101T1 (en) | 2003-08-04 | 2008-10-15 | Camurus Ab | METHOD FOR LOADING AMPHIPHIL PARTICLES WITH ACTIVE SUBSTANCES |
EP1663295A2 (en) | 2003-09-01 | 2006-06-07 | Novo Nordisk A/S | Stable formulations of peptides |
GB0322033D0 (en) | 2003-09-19 | 2003-10-22 | Camurus Ab | Composition |
DK1682091T3 (en) | 2003-11-07 | 2017-05-15 | Camurus Ab | COMPOSITIONS OF LIPIDS AND CATIONIC PEPTIDES |
WO2005063213A1 (en) | 2003-12-19 | 2005-07-14 | Biodelivery Sciences International, Inc. | Rigid liposomal cochleate and methods of use and manufacture |
GB0401513D0 (en) | 2004-01-23 | 2004-02-25 | Camurus Ab | Compositions |
DE602005025083D1 (en) | 2004-01-23 | 2011-01-13 | Camurus Ab | |
RU2390331C2 (en) | 2004-06-04 | 2010-05-27 | Камурус Аб | Liquid drug reservoirs |
CA2575906C (en) | 2004-08-04 | 2014-04-15 | Camurus Ab | Compositions forming non-lamellar dispersions |
ES2400034T3 (en) | 2005-01-14 | 2013-04-05 | Camurus Ab | Topical bioadhesive formulations |
CA2594710C (en) | 2005-01-14 | 2011-01-25 | Camurus Ab | Topical bioadhesive formulations |
DE602005026998D1 (en) | 2005-01-14 | 2011-04-28 | Camurus Ab | SOMATOSTATIN-ANALOG FORMULATIONS |
PL1843746T3 (en) * | 2005-01-14 | 2011-09-30 | Camurus Ab | Somatostatin analogue formulations |
KR101245022B1 (en) | 2005-01-21 | 2013-03-19 | 카무러스 에이비 | Pharmaceutical lipid compositions |
DK1888031T3 (en) | 2005-06-06 | 2013-02-18 | Camurus Ab | GLP-1 analog formulations |
CA2629300C (en) | 2005-11-17 | 2014-07-08 | Zogenix, Inc. | Delivery of viscous formulations by needle-free injection |
GB0602639D0 (en) * | 2006-02-09 | 2006-03-22 | Novartis Ag | Organic compounds |
AR066677A1 (en) * | 2007-05-24 | 2009-09-02 | Novartis Ag | FORMATION OF PASSIREOTIDE. PHARMACEUTICAL COMPOSITION FOR PROLONGED RELEASE. MICROPARTICLES. |
GB0711656D0 (en) * | 2007-06-15 | 2007-07-25 | Camurus Ab | Formulations |
GB0716385D0 (en) | 2007-08-22 | 2007-10-03 | Camurus Ab | Formulations |
PT2310042E (en) * | 2008-07-08 | 2013-03-11 | Novartis Ag | Use of pasireotide for the treatment of endogenous hyperinsulinemic hypoglycemia |
GB0815435D0 (en) | 2008-08-22 | 2008-10-01 | Camurus Ab | Formulations |
US11433120B2 (en) * | 2011-05-25 | 2022-09-06 | Camurus Ab | Controlled release peptide formulations |
CN104093399B (en) * | 2011-12-05 | 2018-03-13 | 卡穆鲁斯公司 | Robustness controlled release peptide formulations |
-
2013
- 2013-05-24 PE PE2014002215A patent/PE20150195A1/en not_active Application Discontinuation
- 2013-05-24 NZ NZ702028A patent/NZ702028A/en not_active IP Right Cessation
- 2013-05-24 CN CN201380034030.8A patent/CN104487050B/en active Active
- 2013-05-24 CA CA2874367A patent/CA2874367C/en active Active
- 2013-05-24 MX MX2014014379A patent/MX350964B/en active IP Right Grant
- 2013-05-24 JP JP2015513209A patent/JP6374380B2/en active Active
- 2013-05-24 MA MA37672A patent/MA37672A1/en unknown
- 2013-05-24 WO PCT/EP2013/060739 patent/WO2013174978A1/en active Application Filing
- 2013-05-24 US US14/401,559 patent/US11672843B2/en active Active
- 2013-05-24 AU AU2013265210A patent/AU2013265210B2/en active Active
- 2013-05-24 KR KR1020147036398A patent/KR102139080B1/en active IP Right Grant
- 2013-05-24 IN IN9831DEN2014 patent/IN2014DN09831A/en unknown
- 2013-05-24 DK DK13724299.6T patent/DK2861209T3/en active
- 2013-05-24 ES ES13724299T patent/ES2834318T3/en active Active
- 2013-05-24 BR BR112014029425A patent/BR112014029425A2/en not_active Application Discontinuation
- 2013-05-24 EA EA201491928A patent/EA035495B1/en not_active IP Right Cessation
- 2013-05-24 SG SG11201407678YA patent/SG11201407678YA/en unknown
-
2014
- 2014-11-17 IL IL235740A patent/IL235740A0/en unknown
- 2014-11-21 TN TN2014000483A patent/TN2014000483A1/en unknown
- 2014-11-24 PH PH12014502614A patent/PH12014502614A1/en unknown
- 2014-11-24 CL CL2014003185A patent/CL2014003185A1/en unknown
- 2014-12-18 CO CO14278535A patent/CO7160067A2/en unknown
-
2015
- 2015-09-08 HK HK15108712.3A patent/HK1207985A1/en unknown
-
2023
- 2023-04-26 US US18/307,124 patent/US20230372436A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
AU2013265210A1 (en) | 2014-12-04 |
NZ702028A (en) | 2016-07-29 |
TN2014000483A1 (en) | 2016-03-30 |
CA2874367C (en) | 2020-08-18 |
MX2014014379A (en) | 2015-02-05 |
CL2014003185A1 (en) | 2015-04-24 |
PE20150195A1 (en) | 2015-02-27 |
US11672843B2 (en) | 2023-06-13 |
EA035495B1 (en) | 2020-06-25 |
ES2834318T3 (en) | 2021-06-17 |
CN104487050B (en) | 2019-08-20 |
HK1207985A1 (en) | 2016-02-19 |
IN2014DN09831A (en) | 2015-08-07 |
AU2013265210B2 (en) | 2016-09-15 |
EA201491928A1 (en) | 2015-09-30 |
MX350964B (en) | 2017-09-27 |
WO2013174978A1 (en) | 2013-11-28 |
KR20150016977A (en) | 2015-02-13 |
CA2874367A1 (en) | 2013-11-28 |
BR112014029425A2 (en) | 2017-06-27 |
JP2015520762A (en) | 2015-07-23 |
KR102139080B1 (en) | 2020-07-29 |
US20150105332A1 (en) | 2015-04-16 |
CN104487050A (en) | 2015-04-01 |
DK2861209T3 (en) | 2020-12-21 |
MA37672A1 (en) | 2016-07-29 |
PH12014502614A1 (en) | 2015-01-21 |
JP6374380B2 (en) | 2018-08-15 |
CO7160067A2 (en) | 2015-01-15 |
US20230372436A1 (en) | 2023-11-23 |
IL235740A0 (en) | 2015-01-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
SG11201809857TA (en) | Anti-CTLA-4 Antibodies | |
SG11201903331QA (en) | Restimulation of cryopreserved tumor infiltrating lymphocytes | |
SG11201809132RA (en) | Novel compounds as autotaxin inhibitors and pharmaceutical compositions comprising the same | |
SG11201407228PA (en) | N-aryltriazole compounds as lpar antagonists | |
SG11201805570WA (en) | Systems and methods for long term transdermal administration | |
SG11201408769QA (en) | Methods of reducing the risk of a cardiovascular event in a subject on statin therapy | |
SG11201810628XA (en) | Nasal pharmaceutical compositions with a porous excipient | |
SG11201408095XA (en) | Fibroblast growth factor 21 proteins | |
SG11201407200TA (en) | Liquid formulation | |
SG11201901558VA (en) | Pth compounds with low peak-to-trough ratios | |
SG11201407747QA (en) | A method and apparatus for facilitating the management of health and security | |
SG11201407397WA (en) | Formulations and methods for vaginal delivery of antiprogestins | |
SG11201808566WA (en) | Polymorphic form of n-{6-(2-hydroxypropan-2-yl)-2-[2-(methylsulphonyl)ethyl]-2h-indazol-5-yl}-6-(trifluoromethyl)pyridine-2-carboxamide | |
SG11201811230RA (en) | Compositions and methods for reducing ocular neovascularization | |
SG11201907804QA (en) | Pharmaceutical composition comprising selexipag | |
SG11201407678YA (en) | Somatostatin receptor agonist formulations | |
SG11201906436VA (en) | Novel heterocyclic compound, its preparation method, and pharmaceutical composition comprising the same | |
SG11201900558RA (en) | Spiro-lactam nmda receptor modulators and uses thereof | |
SG11201806393QA (en) | Use of gabaa receptor modulators for treatment of itch | |
SG11201901438VA (en) | Solid forms of cenicriviroc mesylate and processes of making solid forms of cenicriviroc mesylate | |
SG11201808686VA (en) | Synthesis of indazoles | |
SG11201407229UA (en) | Substituted pyrazole compounds as lpar antagonists | |
SG11201805149XA (en) | Compositions comprising 15-hepe and methods of using the same | |
SG11201906767XA (en) | Estrogen receptor modulators | |
SG11201407536UA (en) | Topical pharmaceutical compositions comprising terbinafine and urea |