JP7273421B2 - ナチュラルキラー細胞の活性化および拡大のための方法ならびにその使用 - Google Patents

ナチュラルキラー細胞の活性化および拡大のための方法ならびにその使用 Download PDF

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JP7273421B2
JP7273421B2 JP2020544194A JP2020544194A JP7273421B2 JP 7273421 B2 JP7273421 B2 JP 7273421B2 JP 2020544194 A JP2020544194 A JP 2020544194A JP 2020544194 A JP2020544194 A JP 2020544194A JP 7273421 B2 JP7273421 B2 JP 7273421B2
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カラバイ、ルシラ、ナシフ
シュポール、エリザベス、ジェイ．
レズヴァニ、ケイティ
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University of Texas System
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JP2020544194A 2018-02-21 2019-02-21 ナチュラルキラー細胞の活性化および拡大のための方法ならびにその使用 Active JP7273421B2 (ja)

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US201862633592P 2018-02-21 2018-02-21
US62/633,592 2018-02-21
PCT/US2019/019019 WO2019165121A1 (en) 2018-02-21 2019-02-21 Methods for activation and expansion of natural killer cells and uses therof

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JP2021513859A5 JP2021513859A5 (https=) 2022-03-01
JPWO2019165121A5 JPWO2019165121A5 (https=) 2022-03-01
JP7273421B2 true JP7273421B2 (ja) 2023-05-15

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US (2) US12473336B2 (https=)
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JP7273421B2 (ja) 2018-02-21 2023-05-15 ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム ナチュラルキラー細胞の活性化および拡大のための方法ならびにその使用
US12590148B2 (en) 2018-11-26 2026-03-31 Nkarta, Inc. Methods for the simultaneous expansion of multiple immune cell types, related compositions and uses of same in cancer immunotherapy
AU2020232691B2 (en) 2019-03-05 2023-06-29 Nkarta, Inc. CD19-directed chimeric antigen receptors and uses thereof in immunotherapy
US20210077527A1 (en) * 2019-09-13 2021-03-18 The Research Institute At Nationwide Children's Hospital Universal donor selection method to identify nk-cell-donors
WO2021051088A1 (en) * 2019-09-13 2021-03-18 Ohio State Innovation Foundation Nk cell immunotherapy compositions, methods of making and methods of using same
US12195759B2 (en) 2020-02-21 2025-01-14 FullHope Biomedical Co., Ltd. Modified natural killer cells, pharmaceutical composition, manufacturing method thereof, and method of using the same
AU2021262835A1 (en) * 2020-04-30 2022-11-24 Fibrobiologics, Inc. Immunotherapeutic methods and compositions for targeting cancer fibroblasts
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EP4163366A4 (en) * 2020-06-09 2024-08-21 Samsung Life Public Welfare Foundation GENETICALLY MODIFIED CELL LINE FOR ACTIVATION AND AMPLIFICATION OF NK CELLS AND USE THEREOF
KR20230084470A (ko) 2020-08-14 2023-06-13 카이트 파마 인코포레이티드 면역 세포 기능의 향상
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WO2022216992A1 (en) * 2021-04-08 2022-10-13 Board Of Regents, The University Of Texas System Methods for activation and expansion of natural killer cells and combinations with bispecific antibodies
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CN115369086B (zh) * 2022-02-22 2023-05-12 北京景达生物科技有限公司 一种nk细胞扩大培养的培养方案
WO2023163240A1 (ko) * 2022-02-22 2023-08-31 신동혁 자연살해세포 활성도 신속검사용 자극조성물 및 이를 이용한 자연살해세포 활성도 신속검사방법
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EP4558152A2 (en) * 2022-07-22 2025-05-28 Board of Regents, The University of Texas System Cd3-expressing natural killer cells with enhanced function for adoptive immunotherapy
CN116254230A (zh) * 2022-09-14 2023-06-13 卡瑞济(北京)生命科技有限公司 用于制备和扩增通用型人源化抗cd19 car-nk细胞的方法及其用途
KR102566680B1 (ko) * 2022-09-28 2023-08-14 (주)포에버엔케이 면역세포 및 자연살해세포 배양을 위한 신규한 이중배양 제조방법 및 이의 용도
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CN119286778A (zh) * 2024-12-09 2025-01-10 天津迈默睿生物技术有限公司 一种利用外周血单个核细胞制备记忆性自然杀伤细胞的方法及记忆性自然杀伤细胞的应用
CN120168514A (zh) * 2025-03-21 2025-06-20 英百瑞(杭州)生物医药有限公司 Nk细胞在治疗系统性红斑狼疮中的应用

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