DK2931877T3 - Fremgangsmåder, som modulerer stamcellers immunregulerende virkning - Google Patents

Fremgangsmåder, som modulerer stamcellers immunregulerende virkning Download PDF

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DK2931877T3
DK2931877T3 DK13862510T DK13862510T DK2931877T3 DK 2931877 T3 DK2931877 T3 DK 2931877T3 DK 13862510 T DK13862510 T DK 13862510T DK 13862510 T DK13862510 T DK 13862510T DK 2931877 T3 DK2931877 T3 DK 2931877T3
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modulating
procedures
regulatory effect
immune regulatory
stam
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DK13862510T
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Yufang Shi
Guangwen Ren
Liying Zhang
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Univ Rutgers
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    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
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DK13862510T 2012-12-14 2013-12-14 Fremgangsmåder, som modulerer stamcellers immunregulerende virkning DK2931877T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261737616P 2012-12-14 2012-12-14
PCT/US2013/075208 WO2014093948A1 (en) 2012-12-14 2013-12-14 Methods modulating immunoregulatory effect of stem cells

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DK2931877T3 true DK2931877T3 (da) 2019-11-04

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DK13862510T DK2931877T3 (da) 2012-12-14 2013-12-14 Fremgangsmåder, som modulerer stamcellers immunregulerende virkning

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EP (2) EP3587562B1 (da)
JP (5) JP6377632B2 (da)
KR (2) KR102353601B1 (da)
CN (2) CN109576217A (da)
AU (2) AU2013358904B2 (da)
CA (1) CA2895148C (da)
DK (1) DK2931877T3 (da)
ES (1) ES2756336T3 (da)
HK (1) HK1217211A1 (da)
WO (1) WO2014093948A1 (da)

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CN105079792A (zh) * 2014-05-14 2015-11-25 中国科学院上海生命科学研究院 Il-17在提高间充质干细胞免疫抑制功能中的应用
CN105748514A (zh) * 2015-01-05 2016-07-13 洪士杰 用于治疗肝脏疾病的间叶干细胞
CN105838671A (zh) * 2015-01-16 2016-08-10 中国科学院上海生命科学研究院 I型干扰素及间充质干细胞在制备抗肿瘤药物中的新用途
EP3515462B1 (en) * 2016-09-19 2023-06-14 University of South Florida Method of targeting oncolytic viruses to tumors
KR101971323B1 (ko) * 2016-10-17 2019-04-23 사회복지법인 삼성생명공익재단 면역질환 치료를 위한 고효능 줄기세포 선별방법
WO2018081514A1 (en) * 2016-10-27 2018-05-03 The Trustees Of Columbia University In The City Of New York Immunosuppressive mesenchymal cells and methods for forming same
JP7275441B2 (ja) * 2016-12-12 2023-05-18 ベイジン、ヘルス、アンド、バイオテック、ステム、セル、テクノロジカル、コーポレーション、リミテッド 周産期組織由来間葉系幹細胞：その作製方法および使用
JP7237301B2 (ja) * 2016-12-16 2023-03-13 有限会社大阪空気機械サービス 組織治癒剤
CN107916253A (zh) * 2017-11-01 2018-04-17 上海隆耀生物科技有限公司 一种表达人源免疫刺激因子light的间充质干细胞的制备方法及制得的msc‑l细胞
EP3707515A1 (en) * 2017-11-06 2020-09-16 Kings College London Therapeutic substances, their preparation and diagnostic procedure
JP7306635B2 (ja) * 2017-11-09 2023-07-11 北海道公立大学法人 札幌医科大学 組織再生用医薬及びその製造方法
KR102096150B1 (ko) * 2018-01-05 2020-04-02 재단법인 아산사회복지재단 인터페론 감마로 전처리된 유도만능 줄기세포 유래 중간엽 줄기세포 및 이로부터 유래된 엑소좀을 포함하는 피부질환의 개선, 예방 또는 치료용 조성물
CN108546674B (zh) * 2018-04-28 2021-10-19 暨南大学 预刺激干细胞及其制备方法和应用
KR102074798B1 (ko) * 2018-06-15 2020-02-07 코아스템(주) 자가면역질환 치료에 대한 유효성 예측용 바이오마커, 진단키트 및 치료용 용도
AU2019355201A1 (en) * 2018-10-05 2021-05-20 Board Of Regents, The University Of Texas System Methods for the expansion of mesenchymal stromal cells
CN109706180A (zh) * 2019-01-11 2019-05-03 杭州荣泽生物科技有限公司 一种脐带间充质干细胞过表达ido增强免疫抑制的方法及应用
US20220202868A1 (en) * 2019-02-27 2022-06-30 Tigenix S.A.U. Improved stem cell populations for allogeneic therapy
WO2021007180A1 (en) * 2019-07-05 2021-01-14 Case Western Reserve University Priming media and methods for stem cell culture and therapy
CN112940100B (zh) * 2019-12-10 2022-06-07 湖南赛奥维生物技术有限公司 一种碱性成纤维细胞生长因子替代物及其组合物和应用
KR102268242B1 (ko) * 2020-01-06 2021-06-23 에스씨엠생명과학 주식회사 줄기세포의 기능강화용 조성물
WO2021162554A1 (en) * 2020-02-14 2021-08-19 Academisch Ziekenhuis Leiden H.O.D.N. Lumc Means and methods for determining mesenchymal stromal cell properties.
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CN111206018A (zh) * 2020-02-25 2020-05-29 无锡市人民医院 一种用于治疗急性肝衰竭的间充质干细胞的制备方法
CN112111449A (zh) * 2020-09-03 2020-12-22 高连如 一种免疫调节功能预授权型间充质干细胞、制备方法及注射液
CN113151164B (zh) * 2021-05-08 2023-08-18 中山大学 一种msc的培养基添加剂及其应用
KR20220162394A (ko) * 2021-06-01 2022-12-08 에스씨엠생명과학 주식회사 기능강화 줄기세포 및 조절 t 세포를 포함하는 아토피 피부염 예방 또는 치료용 병용투여 조성물
CN114621919B (zh) * 2022-05-17 2022-12-06 天九再生医学(天津)科技有限公司 一种增强间充质干细胞免疫调节能力的方法
KR20230172252A (ko) * 2022-06-15 2023-12-22 에스씨엠생명과학 주식회사 기능강화 줄기세포를 포함하는 관절염 예방 또는 치료용 조성물
CN115161276B (zh) * 2022-08-24 2023-09-15 深圳市北科生物科技有限公司 Il4、il21、il27至少两种细胞因子处理获得的间充质干细胞及其外泌体和应用
CN115354022A (zh) * 2022-08-24 2022-11-18 深圳市北科生物科技有限公司 Il4、il21、il27至少两种细胞因子处理获得的间充质干细胞及其外泌体和应用
KR102522295B1 (ko) * 2022-08-30 2023-04-18 주식회사 스마트셀랩 말초혈액유래 줄기세포의 분리 및 배양조건과 이를 활용한 전구세포로의 분화유도
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