JP5798285B2 - ヒストン脱アセチル化酵素（ｈｄａｃ）阻害剤としてのチオフェン及びチアゾール置換トリフルオロエタノン誘導体 - Google Patents

ヒストン脱アセチル化酵素（ｈｄａｃ）阻害剤としてのチオフェン及びチアゾール置換トリフルオロエタノン誘導体 Download PDF

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JP5798285B2
JP5798285B2 JP2008554858A JP2008554858A JP5798285B2 JP 5798285 B2 JP5798285 B2 JP 5798285B2 JP 2008554858 A JP2008554858 A JP 2008554858A JP 2008554858 A JP2008554858 A JP 2008554858A JP 5798285 B2 JP5798285 B2 JP 5798285B2
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alkyl
thienyl
compound
phenyl
inhibitors
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JP2009526830A5 (enExample
JP2009526830A (ja
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フェリーニョ，フェデリカ
ジョーンズ，フィリップ
ムラグリア，エステル
オントリア・オントリア，ヘスス・マリア
スカルペッリ，リタ
ファデムレヒト，カルステン シュルツ
ファデムレヒト，カルステン シュルツ
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エンメエッセディ・イタリア・エッセ・エッレ・エッレ
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    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
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JP2008554858A 2006-02-15 2007-02-14 ヒストン脱アセチル化酵素（ｈｄａｃ）阻害剤としてのチオフェン及びチアゾール置換トリフルオロエタノン誘導体 Active JP5798285B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0603041.5A GB0603041D0 (en) 2006-02-15 2006-02-15 Therapeutic compounds
GB0603041.5 2006-02-15
PCT/GB2007/050061 WO2007093827A1 (en) 2006-02-15 2007-02-14 Thiophene and thiazole substituted trifluoroethanone derivatives as histone deacetylase (hdac) inhibitors

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JP2014262112A Division JP6200411B2 (ja) 2006-02-15 2014-12-25 ヒストン脱アセチル化酵素（ｈｄａｃ）阻害剤としてのチオフェン及びチアゾール置換トリフルオロエタノン誘導体

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JP2009526830A JP2009526830A (ja) 2009-07-23
JP2009526830A5 JP2009526830A5 (enExample) 2010-03-18
JP5798285B2 true JP5798285B2 (ja) 2015-10-21

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JP2008554858A Active JP5798285B2 (ja) 2006-02-15 2007-02-14 ヒストン脱アセチル化酵素（ｈｄａｃ）阻害剤としてのチオフェン及びチアゾール置換トリフルオロエタノン誘導体
JP2014262112A Active JP6200411B2 (ja) 2006-02-15 2014-12-25 ヒストン脱アセチル化酵素（ｈｄａｃ）阻害剤としてのチオフェン及びチアゾール置換トリフルオロエタノン誘導体

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US (1) US7799825B2 (enExample)
EP (1) EP1987024B1 (enExample)
JP (2) JP5798285B2 (enExample)
AU (1) AU2007216323B2 (enExample)
CA (1) CA2641933C (enExample)
GB (1) GB0603041D0 (enExample)
WO (1) WO2007093827A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015110584A (ja) * 2006-02-15 2015-06-18 エンメエッセディ・イタリア・エッセ・エッレ・エッレ ヒストン脱アセチル化酵素（ｈｄａｃ）阻害剤としてのチオフェン及びチアゾール置換トリフルオロエタノン誘導体

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AU2005249492B2 (en) 2004-05-27 2011-09-22 The Regents Of The University Of Colorado Methods for prediction of clinical outcome to epidermal growth factor receptor inhibitors by cancer patients
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CA2672776A1 (en) * 2006-12-20 2008-06-26 Novartis Ag 2-substituted 5-membered heterocycles as scd inhibitors
KR101669432B1 (ko) * 2007-08-27 2016-10-26 다트 뉴로사이언스 (케이만) 엘티디. 치료적 이속사졸 화합물
AR072297A1 (es) 2008-06-27 2010-08-18 Novartis Ag Derivados de indol-2-il-piridin-3-ilo, composicion farmaceutica que los comprende y su uso en medicamentos para el tratamiento de enfermedades mediadas por la sintasa aldosterona.
EA201170349A1 (ru) * 2008-08-18 2011-08-30 Йейл Юниверсити Модуляторы mif
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