AU2007216323B2 - Thiophene and thiazole substituted trifluoroethanone derivatives as histone deacetylase (HDAC) inhibitors - Google Patents

Thiophene and thiazole substituted trifluoroethanone derivatives as histone deacetylase (HDAC) inhibitors Download PDF

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AU2007216323B2
AU2007216323B2 AU2007216323A AU2007216323A AU2007216323B2 AU 2007216323 B2 AU2007216323 B2 AU 2007216323B2 AU 2007216323 A AU2007216323 A AU 2007216323A AU 2007216323 A AU2007216323 A AU 2007216323A AU 2007216323 B2 AU2007216323 B2 AU 2007216323B2
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thienyl
compound
ring containing
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AU2007216323A1 (en
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Federica Ferrigno
Philip Jones
Ester Muraglia
Jesus Maria Ontoria Ontoria
Rita Scarpelli
Carsten Schultz-Fademrecht
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MSD Italia SRL
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    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
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    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
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AU2007216323A 2006-02-15 2007-02-14 Thiophene and thiazole substituted trifluoroethanone derivatives as histone deacetylase (HDAC) inhibitors Active AU2007216323B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0603041.5 2006-02-15
GBGB0603041.5A GB0603041D0 (en) 2006-02-15 2006-02-15 Therapeutic compounds
PCT/GB2007/050061 WO2007093827A1 (en) 2006-02-15 2007-02-14 Thiophene and thiazole substituted trifluoroethanone derivatives as histone deacetylase (hdac) inhibitors

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AU2007216323A1 AU2007216323A1 (en) 2007-08-23
AU2007216323B2 true AU2007216323B2 (en) 2012-05-03

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AU2007216323A Active AU2007216323B2 (en) 2006-02-15 2007-02-14 Thiophene and thiazole substituted trifluoroethanone derivatives as histone deacetylase (HDAC) inhibitors

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US (1) US7799825B2 (enExample)
EP (1) EP1987024B1 (enExample)
JP (2) JP5798285B2 (enExample)
AU (1) AU2007216323B2 (enExample)
CA (1) CA2641933C (enExample)
GB (1) GB0603041D0 (enExample)
WO (1) WO2007093827A1 (enExample)

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GB0603041D0 (en) * 2006-02-15 2006-03-29 Angeletti P Ist Richerche Bio Therapeutic compounds
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JP2013517279A (ja) * 2010-01-13 2013-05-16 テンペロ、ファーマシューティカルズ、インコーポレイテッド 化合物及び方法
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FI3328843T3 (fi) * 2015-07-27 2023-01-31 1,3,4-oksadiatsolisulfonamidijohdannaisyhdisteitä histonideasetylaasi-6:n inhibiittoreina ja samaa käsittävä farmaseuttinen koostumus
US10357493B2 (en) 2017-03-10 2019-07-23 Selenity Therapeutics (Bermuda), Ltd. Metalloenzyme inhibitor compounds
KR102316234B1 (ko) 2018-07-26 2021-10-22 주식회사 종근당 히스톤 탈아세틸화효소 6 억제제로서의 1,3,4-옥사다이아졸 유도체 화합물 및 이를 포함하는 약제학적 조성물
WO2020186101A1 (en) 2019-03-12 2020-09-17 The Broad Institute, Inc. Detection means, compositions and methods for modulating synovial sarcoma cells
CN113874369B (zh) 2019-05-31 2024-08-27 株式会社钟根堂 作为组蛋白脱乙酰酶6抑制剂的1,3,4-噁二唑高邻苯二甲酰亚胺衍生化合物及包含其的药物组合物
WO2023219456A1 (ko) * 2022-05-12 2023-11-16 숙명여자대학교 산학협력단 퀴놀린 계열 히스톤디아세틸화 효소 저해활성물질, 이의 제조방법 및 이를 유효성분으로 포함하는 약학적 조성물

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