JP2853864B2 - ヌクレオチド配列を検出する方法 - Google Patents
ヌクレオチド配列を検出する方法Info
- Publication number
- JP2853864B2 JP2853864B2 JP1059492A JP5949289A JP2853864B2 JP 2853864 B2 JP2853864 B2 JP 2853864B2 JP 1059492 A JP1059492 A JP 1059492A JP 5949289 A JP5949289 A JP 5949289A JP 2853864 B2 JP2853864 B2 JP 2853864B2
- Authority
- JP
- Japan
- Prior art keywords
- nucleotide
- diagnostic
- primer
- sequence
- complementary
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6858—Allele-specific amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Nonwoven Fabrics (AREA)
- Communication Cables (AREA)
- Suspension Of Electric Lines Or Cables (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB888805692A GB8805692D0 (en) | 1988-03-10 | 1988-03-10 | Method of detecting nucleotide sequences |
GB8805692 | 1988-03-10 | ||
GB888814170A GB8814170D0 (en) | 1988-06-15 | 1988-06-15 | Method of detecting nucleotide sequences |
GB8814170.0 | 1988-06-15 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPH0242999A JPH0242999A (ja) | 1990-02-13 |
JP2853864B2 true JP2853864B2 (ja) | 1999-02-03 |
Family
ID=26293607
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP1059492A Expired - Lifetime JP2853864B2 (ja) | 1988-03-10 | 1989-03-10 | ヌクレオチド配列を検出する方法 |
Country Status (26)
Country | Link |
---|---|
US (1) | US5595890A (de) |
EP (1) | EP0332435B2 (de) |
JP (1) | JP2853864B2 (de) |
KR (1) | KR970003151B1 (de) |
CN (1) | CN1034673C (de) |
AT (1) | ATE75262T1 (de) |
AU (1) | AU614584B2 (de) |
BG (1) | BG87585A (de) |
BR (1) | BR8901136A (de) |
CA (1) | CA1323592C (de) |
DE (1) | DE68901285D1 (de) |
DK (1) | DK175527B1 (de) |
ES (1) | ES2039294T5 (de) |
FI (1) | FI891126A (de) |
GR (2) | GR3004442T3 (de) |
HU (1) | HUT52565A (de) |
IE (1) | IE61148B1 (de) |
IL (1) | IL89545A (de) |
MY (1) | MY104957A (de) |
NO (1) | NO174825B (de) |
NZ (1) | NZ228266A (de) |
PL (1) | PL162338B1 (de) |
PT (1) | PT89980B (de) |
TN (1) | TNSN89026A1 (de) |
YU (1) | YU49789A (de) |
ZW (1) | ZW3388A1 (de) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010001969A1 (ja) | 2008-07-02 | 2010-01-07 | アークレイ株式会社 | 標的核酸配列の増幅方法、それを用いた変異の検出方法、および、それに用いる試薬 |
US7846696B2 (en) | 2008-07-10 | 2010-12-07 | Olympus Corporation | Method for estimating target nucleic acid ratio |
EP2383348A1 (de) | 2010-04-30 | 2011-11-02 | ARKRAY, Inc. | Verfahren zur Einstellung der Verstärkungseffizienz eines Target-Polynukleotids |
KR20120040705A (ko) | 2010-01-21 | 2012-04-27 | 아크레이 가부시키가이샤 | 표적 서열의 증폭 방법, 다형 검출 방법 및 그것에 사용하는 시약 |
US8530165B2 (en) | 2008-02-05 | 2013-09-10 | Olympus Corporation | Nucleic acid detection method for determining if one or more analyte nucleotides are present in a nucleic acid |
US9340833B2 (en) | 2010-04-30 | 2016-05-17 | Arkray, Inc. | Method for adjusting amplification efficiency of target polynucleotide |
Families Citing this family (254)
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DE4038804A1 (de) * | 1990-10-09 | 1992-04-16 | Boehringer Mannheim Gmbh | Verfahren zur genus- oder/und spezies-spezifischen detektion von bakterien in einer probenfluessigkeit |
EP0333465B1 (de) * | 1988-03-18 | 1994-07-13 | Baylor College Of Medicine | Mutationsnachweis durch kompetitiven Oligonukleotid-Priming |
FR2650840B1 (fr) * | 1989-08-11 | 1991-11-29 | Bertin & Cie | Procede rapide de detection et/ou d'identification d'une seule base sur une sequence d'acide nucleique, et ses applications |
GB8920097D0 (en) * | 1989-09-06 | 1989-10-18 | Ici Plc | Amplification processes |
JPH03123500A (ja) * | 1989-10-06 | 1991-05-27 | Canon Inc | 核酸の分別方法 |
GB9001181D0 (en) * | 1990-01-18 | 1990-03-21 | Imp Cancer Res Tech | Genetic assay |
US6013431A (en) | 1990-02-16 | 2000-01-11 | Molecular Tool, Inc. | Method for determining specific nucleotide variations by primer extension in the presence of mixture of labeled nucleotides and terminators |
IL97222A (en) * | 1990-02-16 | 1995-08-31 | Orion Yhtymae Oy | Method and Responder for Determining Special Changes to Nucleotide |
GB9006924D0 (en) * | 1990-03-28 | 1990-05-23 | Imperial College | Prognosis of hepatitis infection |
US5844108A (en) * | 1990-06-22 | 1998-12-01 | Roche Molecular Systems, Inc. | Primers targeted to NAT2 gene for detection of poor metabolizers of drugs |
DE69126064T2 (de) * | 1990-06-22 | 1997-08-28 | Hoffmann La Roche | Nachweis von schwachen Metabolisierungsreagentien von Drogen |
GB9019512D0 (en) * | 1990-09-06 | 1990-10-24 | Ici Plc | Assay method |
FR2668162B1 (fr) * | 1990-10-17 | 1993-01-22 | Eurobio Lab | Fragments d'adn, procede et coffret de diagnostic pour la detection des porteurs de la mutation delta-f-508 responsable de la mucoviscidose. |
IE66125B1 (en) * | 1991-01-31 | 1995-12-13 | Zeneca Ltd | Detection method for variant nucleotides |
US6004744A (en) | 1991-03-05 | 1999-12-21 | Molecular Tool, Inc. | Method for determining nucleotide identity through extension of immobilized primer |
US5853989A (en) * | 1991-08-27 | 1998-12-29 | Zeneca Limited | Method of characterisation of genomic DNA |
ATE175722T1 (de) * | 1991-08-27 | 1999-01-15 | Zeneca Ltd | Verfahren zur charakterisierung genomischer dna |
DE4129653A1 (de) * | 1991-09-06 | 1993-03-11 | Boehringer Mannheim Gmbh | Verfahren zum nachweis aehnlicher nukleinsaeuren |
IL103935A0 (en) * | 1991-12-04 | 1993-05-13 | Du Pont | Method for the identification of microorganisms by the utilization of directed and arbitrary dna amplification |
US5541060A (en) * | 1992-04-22 | 1996-07-30 | Arch Development Corporation | Detection of glucokinase-linked early-onset non-insulin-dependent diabetes mellitus |
US6207368B1 (en) | 1992-08-04 | 2001-03-27 | Beckman Coulter, Inc. | Methods and reagents for controlling chain extension and ligation chain reactions |
US6180338B1 (en) | 1992-08-04 | 2001-01-30 | Beckman Coulter, Inc. | Method, reagent and kit for the detection and amplification of nucleic acid sequences |
AU4848393A (en) * | 1992-09-25 | 1994-04-26 | Abbott Laboratories | Ligase chain reaction method for detecting small mutations |
US6335184B1 (en) | 1993-07-23 | 2002-01-01 | Bio-Rad Laboratories, Inc. | Linked linear amplification of nucleic acids |
EP0710296A4 (de) * | 1993-07-23 | 1999-05-26 | Bio Rad Laboratories | Lineare vervielfältigung von nukleinsäuren |
AU1911395A (en) * | 1994-02-04 | 1995-08-21 | Beckman Instruments, Inc. | Method, reagent and kit for the detection and amplification of nucleic acid sequences |
DE69521002T3 (de) | 1994-08-12 | 2010-02-25 | The University Of Utah Research Foundation, Salt Lake City | Mutationen des mit 17q verbundenen Ovarial- und Brustkrebs Empfindlichkeitsgens |
CA2196790C (en) | 1994-08-12 | 2000-10-10 | Mark H. Skolnick | 17q-linked breast and ovarian cancer susceptibility gene |
FR2737732B1 (fr) * | 1995-08-07 | 1997-10-10 | Ass Francaise Contre La Myopat | Test co-dominant de diagnostic genetique |
EP0785216B2 (de) | 1995-12-18 | 2006-06-07 | The University of Utah Research Foundation | Chromosom 13 verbundene Brustkrebsempfindlichkeitsgen BRCA2 |
US5837492A (en) | 1995-12-18 | 1998-11-17 | Myriad Genetics, Inc. | Chromosome 13-linked breast cancer susceptibility gene |
DE69637895D1 (de) | 1995-12-22 | 2009-05-20 | Univ Utah Res Found | Ein gen des "langen qt syndroms" (long qt syndrom), welches kvlqt1 kodiert und seine wechselwirkung mit mink |
NO960163D0 (no) * | 1996-01-15 | 1996-01-15 | Thomas Berg | Mutasjonsdeteksjon av bovin |
US5612473A (en) * | 1996-01-16 | 1997-03-18 | Gull Laboratories | Methods, kits and solutions for preparing sample material for nucleic acid amplification |
AU2320597A (en) | 1996-03-19 | 1997-10-10 | Molecular Tool, Inc. | Method for determining the nucleotide sequence of a polynucleotide |
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US6361940B1 (en) | 1996-09-24 | 2002-03-26 | Qiagen Genomics, Inc. | Compositions and methods for enhancing hybridization and priming specificity |
IL119342A0 (en) * | 1996-10-02 | 1997-01-10 | Yeda Research And Development C | Methods for priming and DNA sequencing |
US5888778A (en) * | 1997-06-16 | 1999-03-30 | Exact Laboratories, Inc. | High-throughput screening method for identification of genetic mutations or disease-causing microorganisms using segmented primers |
US6566101B1 (en) | 1997-06-16 | 2003-05-20 | Anthony P. Shuber | Primer extension methods for detecting nucleic acids |
GB9721240D0 (en) * | 1997-10-08 | 1997-12-03 | Zeneca Ltd | Assay |
US6794133B1 (en) | 1997-12-11 | 2004-09-21 | The General Hospital Corporation | Broad range PCR amplification techniques |
WO1999044045A1 (en) * | 1998-02-27 | 1999-09-02 | Massachusetts Institute Of Technology | Single molecule detection with surface-enhanced raman scattering and applications in dna or rna sequencing |
GB9812768D0 (en) | 1998-06-13 | 1998-08-12 | Zeneca Ltd | Methods |
US6207379B1 (en) | 1998-09-11 | 2001-03-27 | One Lambda | Method for amplification of DNA |
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- 1989-03-09 TN TNTNSN89026A patent/TNSN89026A1/fr unknown
- 1989-03-09 MY MYPI89000284A patent/MY104957A/en unknown
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US8530165B2 (en) | 2008-02-05 | 2013-09-10 | Olympus Corporation | Nucleic acid detection method for determining if one or more analyte nucleotides are present in a nucleic acid |
WO2010001969A1 (ja) | 2008-07-02 | 2010-01-07 | アークレイ株式会社 | 標的核酸配列の増幅方法、それを用いた変異の検出方法、および、それに用いる試薬 |
US9115391B2 (en) | 2008-07-02 | 2015-08-25 | Arkray, Inc. | Method of detecting a polymorphism at a polymorphism site |
US7846696B2 (en) | 2008-07-10 | 2010-12-07 | Olympus Corporation | Method for estimating target nucleic acid ratio |
KR20120040705A (ko) | 2010-01-21 | 2012-04-27 | 아크레이 가부시키가이샤 | 표적 서열의 증폭 방법, 다형 검출 방법 및 그것에 사용하는 시약 |
US9284603B2 (en) | 2010-01-21 | 2016-03-15 | Arkray, Inc. | Target sequence amplification method, polymorphism detection method, and reagents for use in the methods |
EP2383348A1 (de) | 2010-04-30 | 2011-11-02 | ARKRAY, Inc. | Verfahren zur Einstellung der Verstärkungseffizienz eines Target-Polynukleotids |
JP2011244816A (ja) * | 2010-04-30 | 2011-12-08 | Arkray Inc | 標的ポリヌクレオチドの増幅効率の調節方法 |
US9340833B2 (en) | 2010-04-30 | 2016-05-17 | Arkray, Inc. | Method for adjusting amplification efficiency of target polynucleotide |
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