JP2021155453A5 - - Google Patents
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- JP2021155453A5 JP2021155453A5 JP2021109852A JP2021109852A JP2021155453A5 JP 2021155453 A5 JP2021155453 A5 JP 2021155453A5 JP 2021109852 A JP2021109852 A JP 2021109852A JP 2021109852 A JP2021109852 A JP 2021109852A JP 2021155453 A5 JP2021155453 A5 JP 2021155453A5
- Authority
- JP
- Japan
- Prior art keywords
- formulation
- months
- exceed
- storing
- polysorbate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 238000009472 formulation Methods 0.000 claims 5
- 239000000203 mixture Substances 0.000 claims 5
- 238000000034 method Methods 0.000 claims 4
- 239000004475 Arginine Substances 0.000 claims 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims 1
- 239000000539 dimer Substances 0.000 claims 1
- 238000006471 dimerization reaction Methods 0.000 claims 1
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 claims 1
- 229940100601 interleukin-6 Drugs 0.000 claims 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 claims 1
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 claims 1
- 229920000053 polysorbate 80 Polymers 0.000 claims 1
- 229940068968 polysorbate 80 Drugs 0.000 claims 1
- 102000005962 receptors Human genes 0.000 claims 1
- 108020003175 receptors Proteins 0.000 claims 1
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023009289A JP7605869B2 (ja) | 2007-12-27 | 2023-01-25 | 高濃度抗体含有溶液製剤 |
| JP2024217173A JP7755720B2 (ja) | 2007-12-27 | 2024-12-12 | 高濃度抗体含有溶液製剤 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2007336310 | 2007-12-27 | ||
| JP2007336310 | 2007-12-27 | ||
| JP2019139465A JP2019206559A (ja) | 2007-12-27 | 2019-07-30 | 高濃度抗体含有溶液製剤 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019139465A Division JP2019206559A (ja) | 2007-12-27 | 2019-07-30 | 高濃度抗体含有溶液製剤 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023009289A Division JP7605869B2 (ja) | 2007-12-27 | 2023-01-25 | 高濃度抗体含有溶液製剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021155453A JP2021155453A (ja) | 2021-10-07 |
| JP2021155453A5 true JP2021155453A5 (enExample) | 2022-06-17 |
| JP7256234B2 JP7256234B2 (ja) | 2023-04-11 |
Family
ID=40824372
Family Applications (8)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009548102A Active JP4937358B2 (ja) | 2007-12-27 | 2008-12-26 | 高濃度抗体含有溶液製剤 |
| JP2011257255A Active JP5906067B2 (ja) | 2007-12-27 | 2011-11-25 | 高濃度抗体含有溶液製剤 |
| JP2015223070A Active JP6259436B2 (ja) | 2007-12-27 | 2015-11-13 | 高濃度抗体含有溶液製剤 |
| JP2017234971A Active JP6567024B2 (ja) | 2007-12-27 | 2017-12-07 | 高濃度抗体含有溶液製剤 |
| JP2019139465A Pending JP2019206559A (ja) | 2007-12-27 | 2019-07-30 | 高濃度抗体含有溶液製剤 |
| JP2021109852A Active JP7256234B2 (ja) | 2007-12-27 | 2021-07-01 | 高濃度抗体含有溶液製剤 |
| JP2023009289A Active JP7605869B2 (ja) | 2007-12-27 | 2023-01-25 | 高濃度抗体含有溶液製剤 |
| JP2024217173A Active JP7755720B2 (ja) | 2007-12-27 | 2024-12-12 | 高濃度抗体含有溶液製剤 |
Family Applications Before (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009548102A Active JP4937358B2 (ja) | 2007-12-27 | 2008-12-26 | 高濃度抗体含有溶液製剤 |
| JP2011257255A Active JP5906067B2 (ja) | 2007-12-27 | 2011-11-25 | 高濃度抗体含有溶液製剤 |
| JP2015223070A Active JP6259436B2 (ja) | 2007-12-27 | 2015-11-13 | 高濃度抗体含有溶液製剤 |
| JP2017234971A Active JP6567024B2 (ja) | 2007-12-27 | 2017-12-07 | 高濃度抗体含有溶液製剤 |
| JP2019139465A Pending JP2019206559A (ja) | 2007-12-27 | 2019-07-30 | 高濃度抗体含有溶液製剤 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023009289A Active JP7605869B2 (ja) | 2007-12-27 | 2023-01-25 | 高濃度抗体含有溶液製剤 |
| JP2024217173A Active JP7755720B2 (ja) | 2007-12-27 | 2024-12-12 | 高濃度抗体含有溶液製剤 |
Country Status (31)
| Country | Link |
|---|---|
| US (12) | US8568720B2 (enExample) |
| EP (1) | EP2238985B2 (enExample) |
| JP (8) | JP4937358B2 (enExample) |
| KR (1) | KR101083616B1 (enExample) |
| CN (2) | CN101883588B (enExample) |
| AR (3) | AR069969A1 (enExample) |
| AU (1) | AU2008344292B2 (enExample) |
| BR (1) | BRPI0818903B8 (enExample) |
| CA (1) | CA2708627C (enExample) |
| CL (1) | CL2008003910A1 (enExample) |
| CO (1) | CO6450630A2 (enExample) |
| CR (1) | CR11594A (enExample) |
| CY (1) | CY1113616T1 (enExample) |
| DK (1) | DK2238985T4 (enExample) |
| EC (1) | ECSP10010370A (enExample) |
| ES (1) | ES2389881T5 (enExample) |
| HR (1) | HRP20120903T4 (enExample) |
| IL (2) | IL206548A (enExample) |
| MA (1) | MA31934B1 (enExample) |
| MX (1) | MX2010004399A (enExample) |
| MY (1) | MY159450A (enExample) |
| NZ (1) | NZ586378A (enExample) |
| PE (1) | PE20091174A1 (enExample) |
| PL (1) | PL2238985T5 (enExample) |
| PT (1) | PT2238985E (enExample) |
| RU (2) | RU2497544C2 (enExample) |
| SG (1) | SG2013049325A (enExample) |
| SI (1) | SI2238985T2 (enExample) |
| TW (1) | TWI375566B (enExample) |
| UA (1) | UA104134C2 (enExample) |
| WO (1) | WO2009084659A1 (enExample) |
Families Citing this family (122)
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|---|---|---|---|---|
| JPH10324639A (ja) | 1997-03-21 | 1998-12-08 | Chugai Pharmaceut Co Ltd | Ｉｌ−６アンタゴニストを有効成分として含有する感作ｔ細胞関与疾患の予防・治療剤 |
| UA80091C2 (en) | 2001-04-02 | 2007-08-27 | Chugai Pharmaceutical Co Ltd | Remedies for infant chronic arthritis-relating diseases and still's disease which contain an interleukin-6 (il-6) antagonist |
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| GB2401040A (en) * | 2003-04-28 | 2004-11-03 | Chugai Pharmaceutical Co Ltd | Method for treating interleukin-6 related diseases |
| EP1728801A4 (en) | 2004-03-24 | 2009-10-21 | Chugai Pharmaceutical Co Ltd | SUBTYP OF A HUMANIZED ANTIBODY AGAINST THE INTERLEUKIN-6 RECEPTOR |
| JO3000B1 (ar) | 2004-10-20 | 2016-09-05 | Genentech Inc | مركبات أجسام مضادة . |
| EP3050963B1 (en) | 2005-03-31 | 2019-09-18 | Chugai Seiyaku Kabushiki Kaisha | Process for production of polypeptide by regulation of assembly |
| US9084777B2 (en) * | 2005-12-28 | 2015-07-21 | Chugai Seiyaku Kabushiki Kaisha | Stabilized antibody-containing formulations |
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| CN106519025B (zh) | 2007-09-26 | 2021-04-23 | 中外制药株式会社 | 利用cdr的氨基酸取代来改变抗体等电点的方法 |
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| DK2493922T3 (en) | 2009-10-26 | 2017-04-24 | Hoffmann La Roche | Process for preparing a glycosylated immunoglobulin |
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