JP2020531471A5 - - Google Patents

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JP2020531471A5
JP2020531471A5 JP2020509088A JP2020509088A JP2020531471A5 JP 2020531471 A5 JP2020531471 A5 JP 2020531471A5 JP 2020509088 A JP2020509088 A JP 2020509088A JP 2020509088 A JP2020509088 A JP 2020509088A JP 2020531471 A5 JP2020531471 A5 JP 2020531471A5
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formula
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methyl
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JP2020531471A (ja
JP7220203B2 (ja
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Priority claimed from PCT/EP2018/072298 external-priority patent/WO2019034764A1/en
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JP2020509088A 2017-08-18 2018-08-17 ピロロベンゾジアゼピン複合体 Active JP7220203B2 (ja)

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US201762547303P 2017-08-18 2017-08-18
US62/547,303 2017-08-18
PCT/EP2018/072298 WO2019034764A1 (en) 2017-08-18 2018-08-17 CONJUGATES OF PYRROLOBENZODIAZEPINE

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JP2020531471A JP2020531471A (ja) 2020-11-05
JP2020531471A5 true JP2020531471A5 (enExample) 2021-09-24
JP7220203B2 JP7220203B2 (ja) 2023-02-09

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JP2020509088A Active JP7220203B2 (ja) 2017-08-18 2018-08-17 ピロロベンゾジアゼピン複合体

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US (1) US11649250B2 (enExample)
EP (1) EP3668874B1 (enExample)
JP (1) JP7220203B2 (enExample)
KR (2) KR102270107B1 (enExample)
CN (1) CN111065638B (enExample)
AU (1) AU2018316532B2 (enExample)
BR (1) BR112020003003A2 (enExample)
CL (1) CL2020000395A1 (enExample)
CO (1) CO2020001751A2 (enExample)
CY (1) CY1125053T1 (enExample)
DK (1) DK3668874T3 (enExample)
EA (1) EA039276B1 (enExample)
ES (1) ES2906965T3 (enExample)
HR (1) HRP20220311T1 (enExample)
IL (1) IL272625B2 (enExample)
LT (1) LT3668874T (enExample)
MX (1) MX384245B (enExample)
MY (1) MY194477A (enExample)
PL (1) PL3668874T3 (enExample)
PT (1) PT3668874T (enExample)
RS (1) RS62928B1 (enExample)
SG (1) SG11202000358YA (enExample)
SI (1) SI3668874T1 (enExample)
SM (1) SMT202200225T1 (enExample)
WO (1) WO2019034764A1 (enExample)
ZA (1) ZA202000397B (enExample)

Families Citing this family (12)

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JP7807375B2 (ja) * 2020-01-13 2026-01-27 シンアフィックス ビー．ブイ． 付加環化を介して両側官能化された抗体
CN115666656A (zh) * 2020-01-13 2023-01-31 西纳福克斯股份有限公司 通过环加成双侧功能化抗体
EP4090377A1 (en) * 2020-01-13 2022-11-23 Synaffix B.V. Conjugates of antibodies an immune cell engagers
JP2024506022A (ja) 2021-02-08 2024-02-08 シンアフィックス ビー．ブイ． 多機能性抗体
GB202105186D0 (en) 2021-04-12 2021-05-26 Medimmune Ltd Pyrrolobenzodiazepine conjugates
US20230201366A1 (en) 2021-11-19 2023-06-29 Adc Therapeutics Sa Anti-psma conjugates
US20230285580A1 (en) 2021-11-19 2023-09-14 Adc Therapeutics Sa Anti-il-13ralpha2 conjugates
US20250367307A1 (en) 2022-06-30 2025-12-04 Toray Industries, Inc. Pharmaceutical composition for cancer treatment and/or prevention
WO2024038065A1 (en) 2022-08-15 2024-02-22 Synaffix B.V. Anthracyclins and conjugates thereof
EP4389152A1 (en) 2022-12-23 2024-06-26 Synaffix B.V. Conjugates of pbd prodrugs
EP4450093A1 (en) 2023-04-17 2024-10-23 Synaffix B.V. Cleavable immune cell engagers
CN121219014A (zh) 2023-04-17 2025-12-26 西纳福克斯股份有限公司 可切割的免疫细胞接合器

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