|
US3361742A
(en)
|
1964-12-07 |
1968-01-02 |
Hoffmann La Roche |
5-oxo-1h-pyrrolo-[2, 1-c][1, 4]-benzodiazepin-2-crylamides
|
|
US3523941A
(en)
|
1967-03-06 |
1970-08-11 |
Hoffmann La Roche |
Benzodiazepine compounds and process for their preparation
|
|
US3524849A
(en)
|
1967-10-27 |
1970-08-18 |
Hoffmann La Roche |
Process for the preparation of pyrrolo-benzodiazepine acrylamides and intermediates useful therein
|
|
FR2027356A1
(en)
|
1968-12-30 |
1970-09-25 |
Fujisawa Pharmaceutical Co |
Benzodiazepinone antibiotics
|
|
IL33558A
(en)
|
1968-12-30 |
1973-10-25 |
Fujisawa Pharmaceutical Co |
Antibiotic pyrrolo-benzodiazepine compound,its derivatives and processes for their production
|
|
JPS4843755B1
(enExample)
|
1969-06-26 |
1973-12-20 |
|
|
|
JPS6053033B2
(ja)
|
1976-12-28 |
1985-11-22 |
財団法人微生物化学研究会 |
新制癌抗生物質マゼスラマイシン及びその製造方法
|
|
JPS585916B2
(ja)
|
1977-12-27 |
1983-02-02 |
株式会社ミドリ十字 |
新規ベンゾジアゼピン系化合物
|
|
JPS5615289A
(en)
|
1979-07-17 |
1981-02-14 |
Green Cross Corp:The |
Novel benzodiazepinnbased compound 3
|
|
JPS57131791A
(en)
|
1980-12-31 |
1982-08-14 |
Fujisawa Pharmaceut Co Ltd |
Benzodiazepine derivative and its preparation
|
|
CA1184175A
(en)
|
1981-02-27 |
1985-03-19 |
Walter Hunkeler |
Imidazodiazepines
|
|
CA1173441A
(en)
|
1981-02-27 |
1984-08-28 |
Hoffmann-La Roche Limited |
Imidazodiazepines
|
|
CA1185602A
(en)
|
1981-02-27 |
1985-04-16 |
Emilio Kyburz |
Imidazodiazepines
|
|
JPS58180487A
(ja)
|
1982-04-16 |
1983-10-21 |
Kyowa Hakko Kogyo Co Ltd |
抗生物質dc−81およびその製造法
|
|
US4427588A
(en)
|
1982-11-08 |
1984-01-24 |
Bristol-Myers Company |
Process for conversion of oxotomaymycin to tomaymycin
|
|
US4427587A
(en)
|
1982-11-10 |
1984-01-24 |
Bristol-Myers Company |
Total synthesis of antitumor antibiotics BBM-2040A and BBM-2040B
|
|
JPS59152329A
(ja)
|
1983-02-17 |
1984-08-31 |
Green Cross Corp:The |
局所障害抑制剤
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
FR2586683B1
(fr)
|
1985-08-29 |
1988-07-01 |
Centre Nat Rech Scient |
Nouveaux derives de neothramycine, leur procede de preparation et leur application en tant que medicaments
|
|
US5583024A
(en)
|
1985-12-02 |
1996-12-10 |
The Regents Of The University Of California |
Recombinant expression of Coleoptera luciferase
|
|
JP2660201B2
(ja)
|
1988-08-05 |
1997-10-08 |
塩野義製薬株式会社 |
新規ピロロ[1,4]ベンゾジアゼピン誘導体および老人性痴呆薬
|
|
WO1991002536A1
(en)
|
1989-08-23 |
1991-03-07 |
Scripps Clinic And Research Foundation |
Compositions and methods for detection and treatment of epstein-barr virus infection and immune disorders
|
|
JPH053790A
(ja)
|
1990-04-19 |
1993-01-14 |
Fujisawa Pharmaceut Co Ltd |
デヒドロペプチダーゼ−i
|
|
US5256643A
(en)
|
1990-05-29 |
1993-10-26 |
The Government Of The United States |
Human cripto protein
|
|
WO1992007574A1
(en)
|
1990-10-25 |
1992-05-14 |
Tanox Biosystems, Inc. |
Glycoproteins associated with membrane-bound immunoglobulins as antibody targets on b cells
|
|
US5440021A
(en)
|
1991-03-29 |
1995-08-08 |
Chuntharapai; Anan |
Antibodies to human IL-8 type B receptor
|
|
US5543503A
(en)
|
1991-03-29 |
1996-08-06 |
Genentech Inc. |
Antibodies to human IL-8 type A receptor
|
|
CA2105998C
(en)
|
1991-03-29 |
2003-05-13 |
James Lee |
Human pf4a receptors and their use
|
|
FR2676230B1
(fr)
|
1991-05-07 |
1993-08-27 |
Centre Nat Rech Scient |
Nouveaux derives de pyrrolo [1,4]-benzodiazepines, leur procede de preparation et medicaments les contenant.
|
|
JP3050424B2
(ja)
|
1991-07-12 |
2000-06-12 |
塩野義製薬株式会社 |
ヒトエンドセリンリセプター
|
|
US5264557A
(en)
|
1991-08-23 |
1993-11-23 |
The United States Of America As Represented By The Department Of Health And Human Services |
Polypeptide of a human cripto-related gene, CR-3
|
|
US5362852A
(en)
|
1991-09-27 |
1994-11-08 |
Pfizer Inc. |
Modified peptide derivatives conjugated at 2-hydroxyethylamine moieties
|
|
US6153408A
(en)
|
1991-11-15 |
2000-11-28 |
Institut Pasteur And Institut National De La Sante Et De La Recherche Medicale |
Altered major histocompatibility complex (MHC) determinant and methods of using the determinant
|
|
US6011146A
(en)
|
1991-11-15 |
2000-01-04 |
Institut Pasteur |
Altered major histocompatibility complex (MHC) determinant and methods of using the determinant
|
|
GB9205051D0
(en)
|
1992-03-09 |
1992-04-22 |
Cancer Res Campaign Tech |
Pyrrolobenzodiazepine derivatives,their preparation,and compositions containing them
|
|
FR2696176B1
(fr)
|
1992-09-28 |
1994-11-10 |
Synthelabo |
Dérivés de pipéridine, leur préparation et leur application en thérapeutique.
|
|
IL107366A
(en)
|
1992-10-23 |
2003-03-12 |
Chugai Pharmaceutical Co Ltd |
Genes coding for megakaryocyte potentiator
|
|
US5644033A
(en)
|
1992-12-22 |
1997-07-01 |
Health Research, Inc. |
Monoclonal antibodies that define a unique antigen of human B cell antigen receptor complex and methods of using same for diagnosis and treatment
|
|
US5869445A
(en)
|
1993-03-17 |
1999-02-09 |
University Of Washington |
Methods for eliciting or enhancing reactivity to HER-2/neu protein
|
|
US5801005A
(en)
|
1993-03-17 |
1998-09-01 |
University Of Washington |
Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated
|
|
US6214345B1
(en)
|
1993-05-14 |
2001-04-10 |
Bristol-Myers Squibb Co. |
Lysosomal enzyme-cleavable antitumor drug conjugates
|
|
GB9316162D0
(en)
|
1993-08-04 |
1993-09-22 |
Zeneca Ltd |
Fungicides
|
|
US5773223A
(en)
|
1993-09-02 |
1998-06-30 |
Chiron Corporation |
Endothelin B1, (ETB1) receptor polypeptide and its encoding nucleic acid methods, and uses thereof
|
|
EP0647450A1
(en)
|
1993-09-09 |
1995-04-12 |
BEHRINGWERKE Aktiengesellschaft |
Improved prodrugs for enzyme mediated activation
|
|
US5750370A
(en)
|
1995-06-06 |
1998-05-12 |
Human Genome Sciences, Inc. |
Nucleic acid encoding human endothlein-bombesin receptor and method of producing the receptor
|
|
JPH08336393A
(ja)
|
1995-04-13 |
1996-12-24 |
Mitsubishi Chem Corp |
光学活性なγ−置換−β−ヒドロキシ酪酸エステルの製造法
|
|
US5707829A
(en)
|
1995-08-11 |
1998-01-13 |
Genetics Institute, Inc. |
DNA sequences and secreted proteins encoded thereby
|
|
US20020193567A1
(en)
|
1995-08-11 |
2002-12-19 |
Genetics Institute, Inc. |
Secreted proteins and polynucleotides encoding them
|
|
JP3646191B2
(ja)
|
1996-03-19 |
2005-05-11 |
大塚製薬株式会社 |
ヒト遺伝子
|
|
US6218519B1
(en)
|
1996-04-12 |
2001-04-17 |
Pro-Neuron, Inc. |
Compounds and methods for the selective treatment of cancer and bacterial infections
|
|
KR20000011101A
(ko)
|
1996-05-17 |
2000-02-25 |
둘락 노먼 씨. |
사람 b-세포 항원, 관련 시제
|
|
AU739028B2
(en)
|
1996-09-27 |
2001-10-04 |
Bristol-Myers Squibb Company |
Hydrolyzable prodrugs for delivery of anticancer drugs to metastatic cells
|
|
US6759509B1
(en)
|
1996-11-05 |
2004-07-06 |
Bristol-Myers Squibb Company |
Branched peptide linkers
|
|
US5945511A
(en)
|
1997-02-20 |
1999-08-31 |
Zymogenetics, Inc. |
Class II cytokine receptor
|
|
US20030185830A1
(en)
|
1997-02-25 |
2003-10-02 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of prostate cancer
|
|
US7033827B2
(en)
|
1997-02-25 |
2006-04-25 |
Corixa Corporation |
Prostate-specific polynucleotide compositions
|
|
EP2343085B1
(en)
|
1997-03-10 |
2014-12-10 |
The Regents of The University of California |
Antibody against prostate stem cell antigen (PSCA)
|
|
US6261791B1
(en)
|
1997-03-10 |
2001-07-17 |
The Regents Of The University Of California |
Method for diagnosing cancer using specific PSCA antibodies
|
|
US6541212B2
(en)
|
1997-03-10 |
2003-04-01 |
The Regents Of The University Of California |
Methods for detecting prostate stem cell antigen protein
|
|
US6555339B1
(en)
|
1997-04-14 |
2003-04-29 |
Arena Pharmaceuticals, Inc. |
Non-endogenous, constitutively activated human protein-coupled receptors
|
|
US6319688B1
(en)
|
1997-04-28 |
2001-11-20 |
Smithkline Beecham Corporation |
Polynucleotide encoding human sodium dependent phosphate transporter (IPT-1)
|
|
WO1998051824A1
(en)
|
1997-05-15 |
1998-11-19 |
Abbott Laboratories |
Reagents and methods useful for detecting disease of the urinary tract
|
|
US6890749B2
(en)
|
1997-05-15 |
2005-05-10 |
Abbott Laboratories |
Reagents and methods useful for detecting diseases of the prostate
|
|
US6602677B1
(en)
|
1997-09-19 |
2003-08-05 |
Promega Corporation |
Thermostable luciferases and methods of production
|
|
US20030060612A1
(en)
|
1997-10-28 |
2003-03-27 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
|
US20020034749A1
(en)
|
1997-11-18 |
2002-03-21 |
Billing-Medel Patricia A. |
Reagents and methods useful for detecting diseases of the breast
|
|
US6110695A
(en)
|
1997-12-02 |
2000-08-29 |
The Regents Of The University Of California |
Modulating the interaction of the chemokine, B Lymphocyte Hemoattractant, and its Receptor, BLR1
|
|
WO2004031238A2
(en)
|
2002-10-03 |
2004-04-15 |
Mcgill Univeristy |
Antibodies and cyclic peptides which bind cea (carcinoembryonic antigen) and their use as cancer therapeutics
|
|
JP4603157B2
(ja)
|
1998-03-13 |
2010-12-22 |
ザ バーナム インスティチュート |
種々の選択された器官または組織にホーミングする分子
|
|
ATE518956T1
(de)
|
1998-05-13 |
2011-08-15 |
Epimmune Inc |
Expressionsvektoren zur stimulierung einer immunantwort und verfahren zu deren verwendung
|
|
US20030064397A1
(en)
|
1998-05-22 |
2003-04-03 |
Incyte Genomics, Inc. |
Transmembrane protein differentially expressed in prostate and lung tumors
|
|
US20020187472A1
(en)
|
2001-03-09 |
2002-12-12 |
Preeti Lal |
Steap-related protein
|
|
HK1040052B
(zh)
|
1998-05-22 |
2006-09-15 |
第一制药株式会社 |
药物复合物
|
|
WO2002016429A2
(en)
|
2000-08-24 |
2002-02-28 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
|
US20020113770A1
(en)
|
1998-07-08 |
2002-08-22 |
Joseph M. Jacobson |
Methods for achieving improved color in microencapsulated electrophoretic devices
|
|
GB9818731D0
(en)
|
1998-08-27 |
1998-10-21 |
Univ Portsmouth |
Compounds
|
|
WO2000012130A1
(en)
|
1998-08-27 |
2000-03-09 |
Smithkline Beecham Corporation |
Rp105 agonists and antagonists
|
|
GB9818732D0
(en)
|
1998-08-27 |
1998-10-21 |
Univ Portsmouth |
Collection of compounds
|
|
ES2244210T3
(es)
|
1998-08-27 |
2005-12-01 |
Spirogen Limited |
Pirrolobenzodiazepinas.
|
|
GB9818730D0
(en)
|
1998-08-27 |
1998-10-21 |
Univ Portsmouth |
Collections of compounds
|
|
JP4689781B2
(ja)
|
1998-09-03 |
2011-05-25 |
独立行政法人科学技術振興機構 |
アミノ酸輸送蛋白及びその遺伝子
|
|
WO2000020579A1
(en)
|
1998-10-02 |
2000-04-13 |
Mcmaster University |
Spliced form of erbb-2/neu oncogene
|
|
US6962980B2
(en)
|
1999-09-24 |
2005-11-08 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
US6858710B2
(en)
|
1998-12-17 |
2005-02-22 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
US20020119158A1
(en)
|
1998-12-17 |
2002-08-29 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
US6468546B1
(en)
|
1998-12-17 |
2002-10-22 |
Corixa Corporation |
Compositions and methods for therapy and diagnosis of ovarian cancer
|
|
US20030091580A1
(en)
|
2001-06-18 |
2003-05-15 |
Mitcham Jennifer L. |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
JP2002536966A
(ja)
|
1998-12-30 |
2002-11-05 |
ベス・イスラエル・ディーコニス・メディカル・センター・インコーポレーテッド |
カルシウムチャネルファミリーの特徴付け
|
|
CA2361009C
(en)
|
1999-01-29 |
2012-10-23 |
Corixa Corporation |
Her-2/neu fusion proteins
|
|
GB9905124D0
(en)
|
1999-03-05 |
1999-04-28 |
Smithkline Beecham Biolog |
Novel compounds
|
|
US7465785B2
(en)
|
1999-03-08 |
2008-12-16 |
Genentech, Inc. |
Polypeptide encoded by a nucleic acid over-expressed in melanoma
|
|
AU3395900A
(en)
|
1999-03-12 |
2000-10-04 |
Human Genome Sciences, Inc. |
Human lung cancer associated gene sequences and polypeptides
|
|
US7304126B2
(en)
|
1999-05-11 |
2007-12-04 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US6268488B1
(en)
|
1999-05-25 |
2001-07-31 |
Barbas, Iii Carlos F. |
Prodrug activation using catalytic antibodies
|
|
AU4952600A
(en)
|
1999-06-03 |
2000-12-28 |
Takeda Chemical Industries Ltd. |
Screening method with the use of cd100
|
|
HU230586B1
(hu)
|
1999-06-25 |
2017-02-28 |
Genentech, Inc. |
Anti-ErbB antitest/maytansinoid konjugátumok alkalmazása rákos betegségek kezelésére szolgáló gyógyszer előállítására
|
|
US6302318B1
(en)
|
1999-06-29 |
2001-10-16 |
General Electric Company |
Method of providing wear-resistant coatings, and related articles
|
|
US20030119113A1
(en)
|
1999-07-20 |
2003-06-26 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US7297770B2
(en)
|
1999-08-10 |
2007-11-20 |
Genentech, Inc. |
PRO6496 polypeptides
|
|
US7294696B2
(en)
|
1999-08-17 |
2007-11-13 |
Genentech Inc. |
PRO7168 polypeptides
|
|
US6909006B1
(en)
|
1999-08-27 |
2005-06-21 |
Spirogen Limited |
Cyclopropylindole derivatives
|
|
EP1208202A2
(en)
|
1999-09-01 |
2002-05-29 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US20030206918A1
(en)
|
1999-09-10 |
2003-11-06 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
US20030129192A1
(en)
|
1999-09-10 |
2003-07-10 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
US20030232056A1
(en)
|
1999-09-10 |
2003-12-18 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
US6750054B2
(en)
|
2000-05-18 |
2004-06-15 |
Lexicon Genetics Incorporated |
Human semaphorin homologs and polynucleotides encoding the same
|
|
ES2309012T3
(es)
|
1999-10-29 |
2008-12-16 |
Genentech, Inc. |
Composiciones del anticuerpo anti-psca y a sus procedimientos contra celulas cancerigenas que expresen psca.
|
|
WO2001038490A2
(en)
|
1999-11-29 |
2001-05-31 |
The Trustees Of Columbia University In The City Of New York |
ISOLATION OF FIVE NOVEL GENES CODING FOR NEW Fc RECEPTORS-TYPE MELANOMA INVOLVED IN THE PATHOGENESIS OF LYMPHOMA/MELANOMA
|
|
AU1807401A
(en)
|
1999-11-30 |
2001-06-12 |
Corixa Corporation |
Compositions and methods for therapy and diagnosis of breast cancer
|
|
CA2393738A1
(en)
|
1999-12-10 |
2001-06-14 |
Epimmune Inc. |
Inducing cellular immune responses to her2/neu using peptide and nucleic acid compositions
|
|
DE60040240D1
(de)
|
1999-12-23 |
2008-10-23 |
Zymogenetics Inc |
Löslicher interleukin-20 rezeptor
|
|
NZ502058A
(en)
|
1999-12-23 |
2003-11-28 |
Ovita Ltd |
Isolated mutated nucleic acid molecule for regulation of ovulation rate
|
|
US6610286B2
(en)
|
1999-12-23 |
2003-08-26 |
Zymogenetics, Inc. |
Method for treating inflammation using soluble receptors to interleukin-20
|
|
EP2295079A3
(en)
|
1999-12-23 |
2011-03-23 |
ZymoGenetics, L.L.C. |
Method for treating inflammation
|
|
US20040001827A1
(en)
|
2002-06-28 |
2004-01-01 |
Dennis Mark S. |
Serum albumin binding peptides for tumor targeting
|
|
JP2003518075A
(ja)
|
1999-12-24 |
2003-06-03 |
ジェネンテック・インコーポレーテッド |
生理活性化合物の消失半減期延長のための方法及び組成物
|
|
US7294695B2
(en)
|
2000-01-20 |
2007-11-13 |
Genentech, Inc. |
PRO10268 polypeptides
|
|
AU2001234493A1
(en)
|
2000-01-21 |
2001-07-31 |
Corixa Corporation |
Compounds and methods for prevention and treatment of her-2/neu associated malignancies
|
|
US20030224379A1
(en)
|
2000-01-21 |
2003-12-04 |
Tang Y. Tom |
Novel nucleic acids and polypeptides
|
|
AU2001243142A1
(en)
|
2000-02-03 |
2001-08-14 |
Hyseq, Inc. |
Novel nucleic acids and polypeptides
|
|
US20030186372A1
(en)
|
2000-02-11 |
2003-10-02 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US20030219806A1
(en)
|
2000-02-22 |
2003-11-27 |
Millennium Pharmaceuticals, Inc. |
Novel 18607, 15603, 69318, 12303, 48000, 52920, 5433, 38554, 57301, 58324, 55063, 52991, 59914, 59921 and 33751 molecules and uses therefor
|
|
US20020142377A1
(en)
|
2000-02-22 |
2002-10-03 |
Glucksmann Maria Alexandra |
18607, a novel human calcium channel
|
|
US20040052793A1
(en)
|
2001-02-22 |
2004-03-18 |
Carter Paul J. |
Caspase activivated prodrugs therapy
|
|
US20040002068A1
(en)
|
2000-03-01 |
2004-01-01 |
Corixa Corporation |
Compositions and methods for the detection, diagnosis and therapy of hematological malignancies
|
|
US20040005561A1
(en)
|
2000-03-01 |
2004-01-08 |
Corixa Corporation |
Compositions and methods for the detection, diagnosis and therapy of hematological malignancies
|
|
CA2402293A1
(en)
|
2000-03-07 |
2001-09-13 |
Hyseq, Inc. |
Novel nucleic acids and polypeptides
|
|
AU2001249411B2
(en)
|
2000-03-24 |
2007-02-15 |
Fahri Saatcioglu |
Novel prostate-specific or testis-specific nucleic acid molecules, polypeptides,and diagnostic and therapeutic methods
|
|
WO2001072830A2
(de)
|
2000-03-31 |
2001-10-04 |
Ipf Pharmaceuticals Gmbh |
Diagnostik- und arzneimittel zur untersuchung des zelloberflächenproteoms von tumor- und entzündungszellen sowie zur behandlung von tumorerkrankungen und entzündlichen erkrankungen vorzugsweise mit hilfe einer spezifischen chemokinrezeptor-analyse und der chemokinrezeptor-ligand-interaktion
|
|
AU2001253140A1
(en)
|
2000-04-03 |
2001-10-15 |
The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services |
Tumor markers in ovarian cancer
|
|
JP2003532057A
(ja)
|
2000-04-07 |
2003-10-28 |
アリーナ・フアーマシユーチカルズ・インコーポレーテツド |
非内因性の、構成的に活性化される既知gタンパク質−共役受容体
|
|
WO2001090304A2
(en)
|
2000-05-19 |
2001-11-29 |
Human Genome Sciences, Inc. |
Nucleic acids, proteins, and antibodies
|
|
AU2001275437A1
(en)
|
2000-06-09 |
2001-12-17 |
Idec Pharmaceuticals Corporation |
Gene targets and ligands that bind thereto for treatment and diagnosis of ovarian carcinomas
|
|
JP2004523203A
(ja)
|
2000-06-16 |
2004-08-05 |
インサイト・ゲノミックス・インコーポレイテッド |
Gタンパク質結合受容体
|
|
JP2004528003A
(ja)
|
2000-06-30 |
2004-09-16 |
インサイト・ゲノミックス・インコーポレイテッド |
細胞外マトリクスおよび細胞接着分子
|
|
EP1294885A2
(en)
|
2000-06-30 |
2003-03-26 |
Amgen, Inc. |
B7-like molecules and uses thereof
|
|
WO2002002587A1
(en)
|
2000-06-30 |
2002-01-10 |
Human Genome Sciences, Inc. |
B7-like polynucleotides, polypeptides, and antibodies
|
|
AU2002214531A1
(en)
|
2000-07-03 |
2002-01-30 |
Curagen Corporation |
Proteins and nucleic acids encoding same
|
|
US20040044179A1
(en)
|
2000-07-25 |
2004-03-04 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US6891030B2
(en)
|
2000-07-27 |
2005-05-10 |
Mayo Foundation For Medical Education And Research |
T-cell immunoregulatory molecule
|
|
CA2417671A1
(en)
|
2000-07-28 |
2002-02-07 |
Ulrich Wissenbach |
Trp8, trp9 and trp10, novel markers for cancer
|
|
US7229623B1
(en)
|
2000-08-03 |
2007-06-12 |
Corixa Corporation |
Her-2/neu fusion proteins
|
|
WO2002013847A2
(en)
|
2000-08-14 |
2002-02-21 |
Corixa Corporation |
Methods for diagnosis and therapy of hematological and virus-associated malignancies
|
|
BR0113235A
(pt)
|
2000-08-14 |
2004-06-08 |
Corixa Corp |
Composições e métodos para a terapia e a diagnose de malignidades associadas com her-2/neu
|
|
GB0020953D0
(en)
|
2000-08-24 |
2000-10-11 |
Smithkline Beecham Biolog |
Vaccine
|
|
AU2001290548A1
(en)
|
2000-09-11 |
2002-03-26 |
Hyseq, Inc. |
Novel nucleic acids and polypeptides
|
|
US6613567B1
(en)
|
2000-09-15 |
2003-09-02 |
Isis Pharmaceuticals, Inc. |
Antisense inhibition of Her-2 expression
|
|
DE60121808T2
(de)
|
2000-09-15 |
2007-03-29 |
Zymogenetics, Inc., Seattle |
Verwendung eines polypeptids, welches die extrazelluläre domäne von il-20ra und il-20rb enthält, zur behandlung von entzündungen
|
|
US20030119121A1
(en)
|
2000-09-15 |
2003-06-26 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
UA83458C2
(uk)
|
2000-09-18 |
2008-07-25 |
Байоджен Айдек Ма Інк. |
Виділений поліпептид baff-r (рецептор фактора активації в-клітин сімейства tnf)
|
|
AU9272401A
(en)
|
2000-09-18 |
2002-03-26 |
Biogen Inc |
Cripto mutant and uses thereof
|
|
ATE310724T1
(de)
|
2000-09-19 |
2005-12-15 |
Taiho Pharmaceutical Co Ltd |
Zusammensetzungen und verfahren zur verwendung achirale analoge von cc1065 und den duocarmycinen
|
|
WO2002030268A2
(en)
|
2000-10-13 |
2002-04-18 |
Eos Biotechnology, Inc. |
Methods of diagnosis of prostate cancer, compositions and methods of screening for modulators of prostate cancer
|
|
ATE432986T1
(de)
|
2000-11-07 |
2009-06-15 |
Zymogenetics Inc |
Menschlicher rezeptor für tumor necrosis factor
|
|
US20020150573A1
(en)
|
2000-11-10 |
2002-10-17 |
The Rockefeller University |
Anti-Igalpha-Igbeta antibody for lymphoma therapy
|
|
US20040018194A1
(en)
|
2000-11-28 |
2004-01-29 |
Francisco Joseph A. |
Recombinant anti-CD30 antibodies and uses thereof
|
|
WO2002061087A2
(en)
|
2000-12-19 |
2002-08-08 |
Lifespan Biosciences, Inc. |
Antigenic peptides, such as for g protein-coupled receptors (gpcrs), antibodies thereto, and systems for identifying such antigenic peptides
|
|
US20020159986A1
(en)
|
2001-01-12 |
2002-10-31 |
John Langenfeld |
Bone morphogenetic protein-2 in the treatment and diagnosis of cancer
|
|
US20030119126A1
(en)
|
2001-01-16 |
2003-06-26 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US20030119125A1
(en)
|
2001-01-16 |
2003-06-26 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US7754208B2
(en)
|
2001-01-17 |
2010-07-13 |
Trubion Pharmaceuticals, Inc. |
Binding domain-immunoglobulin fusion proteins
|
|
EP1425302A2
(en)
|
2001-01-24 |
2004-06-09 |
Protein Design Labs |
Methods of diagnosis of breast cancer, compositions and methods of screening for modulators of breast cancer
|
|
US20030073144A1
(en)
|
2001-01-30 |
2003-04-17 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of pancreatic cancer
|
|
WO2002064775A1
(en)
|
2001-02-12 |
2002-08-22 |
Bionomics Limited |
Identification of genes involved in the tumourigenic process
|
|
US20030087250A1
(en)
|
2001-03-14 |
2003-05-08 |
Millennium Pharmaceuticals, Inc. |
Nucleic acid molecules and proteins for the identification, assessment, prevention, and therapy of ovarian cancer
|
|
EP1243276A1
(en)
|
2001-03-23 |
2002-09-25 |
Franciscus Marinus Hendrikus De Groot |
Elongated and multiple spacers containing activatible prodrugs
|
|
US20040236091A1
(en)
|
2001-03-28 |
2004-11-25 |
Chicz Roman M. |
Translational profiling
|
|
WO2003008537A2
(en)
|
2001-04-06 |
2003-01-30 |
Mannkind Corporation |
Epitope sequences
|
|
US6820011B2
(en)
|
2001-04-11 |
2004-11-16 |
The Regents Of The University Of Colorado |
Three-dimensional structure of complement receptor type 2 and uses thereof
|
|
CA2443617C
(en)
|
2001-04-17 |
2013-12-10 |
The Board Of Trustees Of The University Of Arkansas |
Repeat sequences of the ca125 gene and their use for diagnostic and therapeutic interventions
|
|
JP2005527180A
(ja)
|
2001-04-18 |
2005-09-15 |
プロテイン デザイン ラブス, インコーポレイテッド |
肺がんの診断方法、肺がんの修飾因子の組成及びスクリーニングの方法
|
|
AU2002334799B2
(en)
|
2001-04-26 |
2009-05-07 |
Biogen Ma Inc. |
Cripto-specific antibodies
|
|
GEP20074091B
(en)
|
2001-04-26 |
2007-04-25 |
Biogen Idec Inc |
Cripto blocking antibodies and uses thereof
|
|
US6884869B2
(en)
|
2001-04-30 |
2005-04-26 |
Seattle Genetics, Inc. |
Pentapeptide compounds and uses related thereto
|
|
EP1988097A1
(en)
|
2001-05-09 |
2008-11-05 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of prostate cancer
|
|
AU2002344326A1
(en)
|
2001-05-11 |
2002-11-25 |
Sloan-Kettering Institute For Cancer Research |
Nucleic acid sequence encoding ovarian antigen, ca125, and uses thereof
|
|
ATE542545T1
(de)
|
2001-05-24 |
2012-02-15 |
Zymogenetics Inc |
Taci-immunoglobulin-fusionsproteine
|
|
WO2003000842A2
(en)
|
2001-06-04 |
2003-01-03 |
Curagen Corporation |
Novel proteins and nucleic acids encoding same
|
|
WO2002098358A2
(en)
|
2001-06-04 |
2002-12-12 |
Eos Biotechnology, Inc. |
Methods of diagnosis and treatment of androgen-dependent prostate cancer, prostate cancer undergoing androgen-withdrawal, and androgen-independent prostate cancer
|
|
WO2002099140A1
(en)
|
2001-06-05 |
2002-12-12 |
Exelixis, Inc. |
GLRAs AS MODIFIERS OF THE p53 PATHWAY AND METHODS OF USE
|
|
AU2002310256A1
(en)
|
2001-06-05 |
2002-12-16 |
Exelixis Inc. |
Ppp2cs as modifiers of the p53 pathway and methods of use
|
|
US7235358B2
(en)
|
2001-06-08 |
2007-06-26 |
Expression Diagnostics, Inc. |
Methods and compositions for diagnosing and monitoring transplant rejection
|
|
US7125663B2
(en)
|
2001-06-13 |
2006-10-24 |
Millenium Pharmaceuticals, Inc. |
Genes, compositions, kits and methods for identification, assessment, prevention, and therapy of cervical cancer
|
|
JP2005508144A
(ja)
|
2001-06-18 |
2005-03-31 |
イオス バイオテクノロジー,インコーポレイティド |
卵巣癌の診断方法、卵巣癌のモジュレーターをスクリーニングする組成物及び方法
|
|
US7189507B2
(en)
|
2001-06-18 |
2007-03-13 |
Pdl Biopharma, Inc. |
Methods of diagnosis of ovarian cancer, compositions and methods of screening for modulators of ovarian cancer
|
|
AU2002322280A1
(en)
|
2001-06-21 |
2003-01-21 |
Millennium Pharmaceuticals, Inc. |
Compositions, kits, and methods for identification, assessment, prevention, and therapy of breast cancer
|
|
WO2003002717A2
(en)
|
2001-06-28 |
2003-01-09 |
Schering Corporation |
Biological activity of ak155
|
|
US20030120040A1
(en)
|
2001-06-29 |
2003-06-26 |
Genentech, Inc. |
Secreted and Transmembrane polypeptides and nucleic acids encoding the same
|
|
WO2003004529A2
(en)
|
2001-07-02 |
2003-01-16 |
Licentia Ltd. |
Ephrin-tie receptor materials and methods
|
|
US20040076955A1
(en)
|
2001-07-03 |
2004-04-22 |
Eos Biotechnology, Inc. |
Methods of diagnosis of bladder cancer, compositions and methods of screening for modulators of bladder cancer
|
|
WO2003003984A2
(en)
|
2001-07-05 |
2003-01-16 |
Curagen Corporation |
Novel proteins and nucleic acids encoding same
|
|
US7446185B2
(en)
|
2001-07-18 |
2008-11-04 |
The Regents Of The University Of California |
Her2/neu target antigen and use of same to stimulate an immune response
|
|
AU2002337657A1
(en)
|
2001-07-25 |
2003-02-17 |
Millennium Pharmaceuticals, Inc. |
Novel genes, compositions, kits, and methods for identification, assessment, prevention, and therapy of prostate cancer
|
|
EA200601861A1
(ru)
|
2001-08-03 |
2007-02-27 |
Дженентек, Инк. |
ПОЛИПЕПТИДЫ TACIs И BR3 И ИХ ПРИМЕНЕНИЕ
|
|
WO2003016475A2
(en)
|
2001-08-14 |
2003-02-27 |
The General Hospital Corporation |
Nucleic acid and amino acid sequences involved in pain
|
|
US20030092013A1
(en)
|
2001-08-16 |
2003-05-15 |
Vitivity, Inc. |
Diagnosis and treatment of vascular disease
|
|
WO2003018621A2
(en)
|
2001-08-23 |
2003-03-06 |
Oxford Biomedica (Uk) Limited |
Genes
|
|
US6902930B2
(en)
|
2001-08-29 |
2005-06-07 |
Vanderbilt University |
Human Mob-5 (IL-24) receptors and uses thereof
|
|
US20030124579A1
(en)
|
2001-09-05 |
2003-07-03 |
Eos Biotechnology, Inc. |
Methods of diagnosis of ovarian cancer, compositions and methods of screening for modulators of ovarian cancer
|
|
JP2005505271A
(ja)
|
2001-09-06 |
2005-02-24 |
アジェンシス, インコーポレイテッド |
癌の処置および検出において有用なsteap−1と名称が与えられる核酸および対応するタンパク質
|
|
WO2003025138A2
(en)
|
2001-09-17 |
2003-03-27 |
Protein Design Labs, Inc. |
Methods of diagnosis of cancer compositions and methods of screening for modulators of cancer
|
|
IL160933A0
(en)
|
2001-09-18 |
2004-08-31 |
Proteologics Inc |
Methods and compositions for treating ?cap associated diseases
|
|
ES2431929T3
(es)
|
2001-09-18 |
2013-11-28 |
Genentech, Inc. |
Composiciones y procedimientos para el diagnóstico y el tratamiento de tumores
|
|
CA2460621A1
(en)
|
2001-09-19 |
2003-03-27 |
Nuvelo, Inc. |
Novel nucleic acids and polypeptides
|
|
WO2003026577A2
(en)
|
2001-09-24 |
2003-04-03 |
Seattle Genetics, Inc. |
P-amidobenzylethers in drug delivery agents
|
|
US7091186B2
(en)
|
2001-09-24 |
2006-08-15 |
Seattle Genetics, Inc. |
p-Amidobenzylethers in drug delivery agents
|
|
US20030077644A1
(en)
|
2001-09-28 |
2003-04-24 |
Bing Yang |
Diagnosis and treatment of diseases caused by mutations in CD72
|
|
AU2002362436A1
(en)
|
2001-10-03 |
2003-04-14 |
Rigel Pharmaceuticals, Inc. |
Modulators of lymphocyte activation and migration
|
|
US20040249144A1
(en)
|
2001-10-03 |
2004-12-09 |
Zairen Sun |
Regulated breast cancer genes
|
|
CA2842429A1
(en)
|
2001-10-19 |
2003-05-01 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of inflammatory bowel disorders
|
|
US20050123925A1
(en)
|
2002-11-15 |
2005-06-09 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
|
CA2465268A1
(en)
|
2001-10-24 |
2003-05-01 |
National Jewish Medical And Research Center |
Three-dimensional structures of tall-1 and its cognate receptors and modified proteins and methods related thereto
|
|
US7405192B2
(en)
|
2001-10-31 |
2008-07-29 |
Alcon, Inc. |
Bone morphogenic proteins (BMP), BMP receptors and BMP binding proteins and their use in the diagnosis and treatment of glaucoma
|
|
US20030232350A1
(en)
|
2001-11-13 |
2003-12-18 |
Eos Biotechnology, Inc. |
Methods of diagnosis of cancer, compositions and methods of screening for modulators of cancer
|
|
WO2003042661A2
(en)
|
2001-11-13 |
2003-05-22 |
Protein Design Labs, Inc. |
Methods of diagnosis of cancer, compositions and methods of screening for modulators of cancer
|
|
EP1482972A4
(en)
|
2001-11-20 |
2005-11-23 |
Seattle Genetics Inc |
TREATMENT OF IMMUNOLOGICAL DISORDERS USING ANTI-CD30 ANTIBODIES
|
|
WO2003045422A1
(en)
|
2001-11-29 |
2003-06-05 |
Genset S.A. |
Agonists and antagonists of prolixin for the treatment of metabolic disorders
|
|
SI1461428T1
(sl)
|
2001-12-03 |
2012-07-31 |
Alexion Pharma Inc |
Postopek za proizvodnjo hibridnih protiteles
|
|
WO2003048202A2
(en)
|
2001-12-03 |
2003-06-12 |
Asahi Kasei Pharma Corporation |
Nf-kappab activating genes
|
|
EP1504099A4
(en)
|
2001-12-10 |
2006-05-10 |
Nuvelo Inc |
NEW NUCLEIC ACIDS AND POLYPEPTIDES
|
|
US20030134790A1
(en)
|
2002-01-11 |
2003-07-17 |
University Of Medicine And Dentistry Of New Jersey |
Bone Morphogenetic Protein-2 And Bone Morphogenetic Protein-4 In The Treatment And Diagnosis Of Cancer
|
|
US7452675B2
(en)
|
2002-01-25 |
2008-11-18 |
The Queen's Medical Center |
Methods of screening for TRPM4b modulators
|
|
DE60334364D1
(de)
|
2002-02-21 |
2010-11-11 |
Univ California |
Behandlungsverfahren unter verwendung von anti-cd22-antikörpern
|
|
US20040258678A1
(en)
|
2002-02-22 |
2004-12-23 |
Genentech, Inc. |
Compositions and methods for the treatment of immune related diseases
|
|
AU2003224638A1
(en)
|
2002-03-01 |
2003-09-16 |
Exelixis, Inc. |
PDPK1s AS MODIFIERS OF THE p53 PATHWAY AND METHODS OF USE
|
|
WO2003097803A2
(en)
|
2002-05-15 |
2003-11-27 |
Avalon Pharmaceuticals |
Cancer-linked gene as target for chemotherapy
|
|
US6660856B2
(en)
|
2002-03-08 |
2003-12-09 |
Kaohsiung Medical University |
Synthesis of pyrrolo[2,1-c][1,4]benzodiazepine analogues
|
|
EP2258712A3
(en)
|
2002-03-15 |
2011-05-04 |
Multicell Immunotherapeutics, Inc. |
Compositions and Methods to Initiate or Enhance Antibody and Major-histocompatibility Class I or Class II-restricted T Cell Responses by Using Immunomodulatory, Non-coding RNA Motifs
|
|
CA2486490A1
(en)
|
2002-03-19 |
2003-12-31 |
Curagen Corporation |
Therapeutic polypeptides, nucleic acids encoding same, and methods of use
|
|
EP1579186A4
(en)
|
2002-03-21 |
2008-10-08 |
Sunesis Pharmaceuticals Inc |
IDENTIFYING KINASE INHIBITORS
|
|
US7193069B2
(en)
|
2002-03-22 |
2007-03-20 |
Research Association For Biotechnology |
Full-length cDNA
|
|
JP2005521429A
(ja)
|
2002-03-25 |
2005-07-21 |
ユーエービー リサーチ ファウンデーション |
Fcレセプターホモログ、試薬およびこれらの使用
|
|
AU2003222103A1
(en)
|
2002-03-28 |
2003-10-13 |
Idec Pharmaceuticals Corporation |
Novel gene targets and ligands that bind thereto for treatment and diagnosis of colon carcinomas
|
|
US20030194704A1
(en)
|
2002-04-03 |
2003-10-16 |
Penn Sharron Gaynor |
Human genome-derived single exon nucleic acid probes useful for gene expression analysis two
|
|
AU2003223469A1
(en)
|
2002-04-05 |
2003-10-27 |
Agensys, Inc. |
Nucleic acid and corresponding protein entitled 98p4b6 useful in treatment and detection of cancer
|
|
US20040101874A1
(en)
|
2002-04-12 |
2004-05-27 |
Mitokor Inc. |
Targets for therapeutic intervention identified in the mitochondrial proteome
|
|
EP2011886A3
(en)
|
2002-04-16 |
2009-02-11 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
|
US20030224467A1
(en)
|
2002-04-17 |
2003-12-04 |
Osborne C. Kent |
AIB1 as a prognostic marker and predictor of resistance to endocrine therapy
|
|
AU2003228869A1
(en)
|
2002-05-03 |
2003-11-17 |
Incyte Corporation |
Transporters and ion channels
|
|
WO2003101388A2
(en)
|
2002-05-30 |
2003-12-11 |
Bristol-Myers Squibb Company |
Human solute carrier family 7 member 11 (hslc7a11)
|
|
WO2003101283A2
(en)
|
2002-06-04 |
2003-12-11 |
Incyte Corporation |
Diagnostics markers for lung cancer
|
|
CA2488284A1
(en)
|
2002-06-04 |
2003-12-11 |
Avalon Pharmaceuticals, Inc. |
Cancer-linked gene as target for chemotherapy
|
|
ATE500326T1
(de)
|
2002-06-06 |
2011-03-15 |
Oncotherapy Science Inc |
Gene und proteine mit bezug zu menschlichem kolonkrebs
|
|
AU2003242633A1
(en)
|
2002-06-06 |
2003-12-22 |
Molecular Engines Laboratories |
Dudulin genes, non-human animal model: uses in human hematological disease
|
|
US20060228705A1
(en)
|
2002-06-07 |
2006-10-12 |
Reinhard Ebner |
Cancer-linked gene as target for chemotherapy
|
|
WO2003105758A2
(en)
|
2002-06-12 |
2003-12-24 |
Avalon Pharmaceuticals, Inc. |
Cancer-linked gene as target for chemotherapy
|
|
US20040249130A1
(en)
|
2002-06-18 |
2004-12-09 |
Martin Stanton |
Aptamer-toxin molecules and methods for using same
|
|
US20040022727A1
(en)
|
2002-06-18 |
2004-02-05 |
Martin Stanton |
Aptamer-toxin molecules and methods for using same
|
|
WO2004000221A2
(en)
|
2002-06-20 |
2003-12-31 |
The Regents Of The University Of California |
Compositions and methods for modulating lymphocyte activity
|
|
WO2004001004A2
(en)
|
2002-06-21 |
2003-12-31 |
Johns Hopkins University School Of Medicine |
Membrane associated tumor endothelium markers
|
|
DE10229834A1
(de)
|
2002-07-03 |
2004-01-29 |
Zinser Textilmaschinen Gmbh |
Streckwerk für Spinnmaschinen mit nachgeordneter Verdichtungsvorrichtung
|
|
AU2003281515A1
(en)
|
2002-07-19 |
2004-02-09 |
Cellzome Ag |
Protein complexes of cellular networks underlying the development of cancer and other diseases
|
|
BR0313033A
(pt)
|
2002-07-25 |
2007-07-10 |
Genentech Inc |
anticorpos, anticorpos monoclonais, linhagens de células de hibridoma, anticorpos receptores de anti-taci isolados, anticorpos anti -taci, métodos de modulação da atividade biológica
|
|
DK1545613T3
(da)
|
2002-07-31 |
2011-11-14 |
Seattle Genetics Inc |
Auristatinkonjugater og deres anvendelse til behandling af cancer, en autoimmun sygdom eller en infektiøs sygdom
|
|
AU2003294210A1
(en)
|
2002-07-31 |
2004-05-04 |
Seattle Genetics, Inc |
Anti-cd20 antibody-drug conjugates for the treatment of cancer and immune disorders
|
|
WO2004015426A1
(en)
|
2002-08-06 |
2004-02-19 |
Bayer Healthcare Ag |
Diagnostics and therapeutics for diseases associated with human cxc chemokine receptor 5(cxcr5)
|
|
JP2004121218A
(ja)
|
2002-08-06 |
2004-04-22 |
Jenokkusu Soyaku Kenkyusho:Kk |
気管支喘息または慢性閉塞性肺疾患の検査方法
|
|
CA2495389A1
(en)
|
2002-08-19 |
2004-02-26 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
|
EP1572957A4
(en)
|
2002-08-27 |
2007-10-10 |
Bristol Myers Squibb Pharma Co |
IDENTIFICATION OF POLYNUCLEOTIDES FOR PREDICTING THE ACTIVITY OF COMPOUNDS INTERACTING WITH AND / OR MODULATING TYROSINE KINASE PROTEINS AND / OR TYROSINE KINASE PROTEIN PATHWAYS IN MAMMARY CELLS
|
|
WO2004020595A2
(en)
|
2002-08-29 |
2004-03-11 |
Five Prime Therapeutics, Inc. |
Novel human polypeptides encoded by polynucleotides
|
|
WO2004019993A1
(en)
|
2002-08-30 |
2004-03-11 |
Ramot At Tel Aviv University Ltd. |
Self-immolative dendrimers releasing many active moieties upon a single activating event
|
|
AU2002951346A0
(en)
|
2002-09-05 |
2002-09-26 |
Garvan Institute Of Medical Research |
Diagnosis of ovarian cancer
|
|
AU2003270311A1
(en)
|
2002-09-06 |
2004-03-29 |
Mannkind Corporation |
Epitope sequences
|
|
WO2004040000A2
(en)
|
2002-09-09 |
2004-05-13 |
Nura, Inc |
G protein coupled receptors and uses thereof
|
|
JP2004113151A
(ja)
|
2002-09-27 |
2004-04-15 |
Sankyo Co Ltd |
癌遺伝子及びその用途
|
|
WO2004032842A2
(en)
|
2002-10-04 |
2004-04-22 |
Van Andel Research Institute |
Molecular sub-classification of kidney tumors and the discovery of new diagnostic markers
|
|
US20040138269A1
(en)
|
2002-10-11 |
2004-07-15 |
Sugen, Inc. |
Substituted pyrroles as kinase inhibitors
|
|
EP1581169A4
(en)
|
2002-11-08 |
2008-09-17 |
Genentech Inc |
COMPOSITIONS AND METHODS FOR TREATING DISEASES RELATED TO NATURAL K CELLS
|
|
EP1578940A4
(en)
|
2002-11-13 |
2007-12-12 |
Genentech Inc |
METHOD AND COMPOSITIONS FOR DYSPLASED DIAGNOSIS
|
|
WO2004043493A1
(en)
|
2002-11-14 |
2004-05-27 |
Syntarga B.V. |
Prodrugs built as multiple self-elimination-release spacers
|
|
GB0226593D0
(en)
|
2002-11-14 |
2002-12-24 |
Consultants Ltd |
Compounds
|
|
ES2392511T3
(es)
|
2002-11-15 |
2012-12-11 |
Musc Foundation For Research Development |
Moduladores de complemento dianas sobre el receptor 2 de complemento
|
|
EP1578372A4
(en)
|
2002-11-15 |
2007-10-17 |
Univ Arkansas |
Ca125 gene and its use for diagnostic and therapeutic interventions
|
|
AU2003297300A1
(en)
|
2002-11-20 |
2004-06-15 |
Biogen Idec Inc. |
Novel gene targets and ligands that bind thereto for treatment and diagnosis of carcinomas
|
|
EP2410332A1
(en)
|
2002-11-21 |
2012-01-25 |
The University Of Utah |
Method for identifying purinergic modulators of the olfactory system
|
|
WO2004048938A2
(en)
|
2002-11-26 |
2004-06-10 |
Protein Design Labs, Inc. |
Methods of detecting soft tissue sarcoma, compositions and methods of screening for soft tissue sarcoma modulators
|
|
EP1581641A4
(en)
|
2002-12-06 |
2006-11-15 |
Diadexus Inc |
COMPOSITIONS, SPREADING VARIATIONS AND METHODS RELATED TO OVARAL SPECIFIC GENES AND PROTEINS
|
|
US20040157278A1
(en)
|
2002-12-13 |
2004-08-12 |
Bayer Corporation |
Detection methods using TIMP 1
|
|
AU2003299778A1
(en)
|
2002-12-20 |
2004-07-22 |
Protein Design Labs, Inc. |
Antibodies against gpr64 and uses thereof
|
|
AU2003299819A1
(en)
|
2002-12-23 |
2004-07-22 |
Human Genome Sciences, Inc. |
Neutrokine-alpha conjugate, neutrokine-alpha complex, and uses thereof
|
|
JP2007520995A
(ja)
|
2003-01-08 |
2007-08-02 |
ブリストル−マイヤーズ スクイブ カンパニー |
上皮増殖因子受容体モデュレーターに対する感受性を決定するためのバイオマーカーおよび方法
|
|
US20050181375A1
(en)
|
2003-01-10 |
2005-08-18 |
Natasha Aziz |
Novel methods of diagnosis of metastatic cancer, compositions and methods of screening for modulators of metastatic cancer
|
|
US20050227301A1
(en)
|
2003-01-10 |
2005-10-13 |
Polgen |
Cell cycle progression proteins
|
|
WO2004065577A2
(en)
|
2003-01-14 |
2004-08-05 |
Bristol-Myers Squibb Company |
Polynucleotides and polypeptides associated with the nf-kb pathway
|
|
EP1583821A4
(en)
|
2003-01-15 |
2007-07-18 |
Millennium Pharm Inc |
METHODS AND COMPOSITIONS FOR TREATING UROLOGICAL DISORDERS USING GENES 44390, 54181, 211, 5687, 884, 1405, 636, 4421, 5410, 30905, 2045, 16405, 18560, 2047, 33751, 52872, 14063, 20739, 32544, 43239, 44373, 51164, 53010, 16852, 1587, 2207, 22245, 2387, 52908, 69112, 14990, 18547, 115, 579
|
|
CA2516128A1
(en)
|
2003-02-14 |
2004-09-02 |
Sagres Discovery, Inc. |
Therapeutic targets in cancer
|
|
WO2006113909A2
(en)
|
2005-04-19 |
2006-10-26 |
Seattle Genetics, Inc. |
Humanized anti-cd70 binding agents and uses thereof
|
|
US20030224411A1
(en)
|
2003-03-13 |
2003-12-04 |
Stanton Lawrence W. |
Genes that are up- or down-regulated during differentiation of human embryonic stem cells
|
|
GB0321295D0
(en)
|
2003-09-11 |
2003-10-15 |
Spirogen Ltd |
Synthesis of protected pyrrolobenzodiazepines
|
|
CA2543318C
(en)
|
2003-10-22 |
2013-01-08 |
B. Rao Vishnuvajjala |
Pyrrolobenzodiazepine derivatives, compositions comprising the same and methods related thereto
|
|
GB0416511D0
(en)
|
2003-10-22 |
2004-08-25 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
US20050288491A1
(en)
|
2004-02-17 |
2005-12-29 |
Wilson David S |
Super-humanized antibodies against respiratory syncytial virus
|
|
EP1718667B1
(en)
|
2004-02-23 |
2013-01-09 |
Genentech, Inc. |
Heterocyclic self-immolative linkers and conjugates
|
|
GB0404578D0
(en)
|
2004-03-01 |
2004-04-07 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
GB0404574D0
(en)
|
2004-03-01 |
2004-04-07 |
Spirogen Ltd |
Amino acids
|
|
PT2270010E
(pt)
|
2004-03-01 |
2012-03-12 |
Spirogen Ltd |
Derivados de 11-hidroxi-5h-pirrolo[2,1-c][1,4]benzodiazepin- 5-ona como intermediários chave para a preparação de pirrolobenzodiazepinas substituídas em c2
|
|
DE102004010943A1
(de)
|
2004-03-03 |
2005-09-29 |
Degussa Ag |
Verfahren zur Herstellung von N-geschützten 4-Ketprolinderivaten
|
|
EP1723152B1
(en)
|
2004-03-09 |
2015-02-11 |
Spirogen Sàrl |
Pyrrolobenzodiazepines
|
|
FR2869231B1
(fr)
|
2004-04-27 |
2008-03-14 |
Sod Conseils Rech Applic |
Composition therapeutique contenant au moins un derive de la pyrrolobenzodiazepine et la fludarabine
|
|
AU2005244062B8
(en)
|
2004-05-11 |
2010-08-05 |
Cambridge Polymer Group, Inc. |
Methods for making oxidation resistant polymeric material
|
|
GB0410725D0
(en)
|
2004-05-13 |
2004-06-16 |
Spirogen Ltd |
Pyrrolobenzodiazepine therapeutic agents
|
|
BRPI0516284A
(pt)
|
2004-09-23 |
2008-09-02 |
Genentech Inc |
anticorpo construìdo com cisteìna, método de selecionar anticorpos, compostos conjugados de droga-anticorpo, composição farmacêutica, método para matar ou inibir a proliferação de células de tumor, métodos de inibir a proliferação celular e o crescimento de células de tumor, artigo manufaturado e método para produzir um composto
|
|
RU2364643C2
(ru)
|
2004-12-24 |
2009-08-20 |
Сова Денко К.К. |
Способ получения термоэлектрического полупроводникового сплава, модуль термоэлектрического преобразования и термоэлектрическое устройство генерации электроэнергии
|
|
JP2008528668A
(ja)
|
2005-02-03 |
2008-07-31 |
アンチトープ リミテッド |
ヒト抗体及びタンパク質
|
|
US7612062B2
(en)
|
2005-04-21 |
2009-11-03 |
Spirogen Limited |
Pyrrolobenzodiazepines
|
|
GB0508084D0
(en)
|
2005-04-21 |
2005-06-01 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
ATE427949T1
(de)
|
2005-10-05 |
2009-04-15 |
Spirogen Ltd |
4-a4-(5-oxo-2,3,5,11a-tetrahydro-5h-pyrrolo a2, 1-cua1,4ubenzodiazepin-8-yloxy)-butyrylaminou-1 - pyrrol-2-carbonsaurealkylesterderivate und verwandte verbindung zur behandlung einer proliferativen erkrankung
|
|
US20070154906A1
(en)
|
2005-10-05 |
2007-07-05 |
Spirogen Ltd. |
Methods to identify therapeutic candidates
|
|
AU2006302415B2
(en)
|
2005-10-07 |
2012-09-13 |
Exelixis, Inc. |
Azetidines as MEK inhibitors for the treatment of proliferative diseases
|
|
ATE527262T1
(de)
|
2006-01-25 |
2011-10-15 |
Sanofi Sa |
Neue tomaymycin derivate enhaltende zytotoxische mittel
|
|
USRE47123E1
(en)
|
2006-07-18 |
2018-11-13 |
Sanofi |
EPHA2 receptor antagonist antibodies
|
|
DK2059536T3
(da)
|
2006-08-14 |
2014-04-14 |
Xencor Inc |
Optimerede antistoffer, der er rettet mod cd19
|
|
US20080112961A1
(en)
|
2006-10-09 |
2008-05-15 |
Macrogenics, Inc. |
Identification and Engineering of Antibodies with Variant Fc Regions and Methods of Using Same
|
|
EP1914242A1
(en)
|
2006-10-19 |
2008-04-23 |
Sanofi-Aventis |
Novel anti-CD38 antibodies for the treatment of cancer
|
|
WO2008050140A2
(en)
|
2006-10-27 |
2008-05-02 |
Spirogen Limited |
Compounds for treatment of parasitic infection
|
|
US8455622B2
(en)
|
2006-12-01 |
2013-06-04 |
Seattle Genetics, Inc. |
Variant target binding agents and uses thereof
|
|
CN101687037B
(zh)
|
2007-05-08 |
2013-07-10 |
健泰科生物技术公司 |
半胱氨酸改造的抗muc16抗体和抗体药物偶联物
|
|
SI2019104T1
(sl)
|
2007-07-19 |
2013-12-31 |
Sanofi |
Citotoksična sredstva, ki obsegajo nove tomaimicinske derivate, in njihova terapevtska uporaba
|
|
ES2450755T3
(es)
|
2007-10-19 |
2014-03-25 |
Genentech, Inc. |
Anticuerpos anti-TENB2 modificados por ingeniería genética con cisteína, y conjugados de anticuerpo y fármaco
|
|
GB0722087D0
(en)
|
2007-11-09 |
2007-12-19 |
Spirogen Ltd |
Polyamides
|
|
GB0722088D0
(en)
|
2007-11-09 |
2007-12-19 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
ES2647927T3
(es)
|
2008-03-18 |
2017-12-27 |
Seattle Genetics, Inc. |
Conjugados enlazadores del fármaco auriestatina
|
|
KR101892411B1
(ko)
|
2008-04-30 |
2018-08-27 |
이뮤노젠 아이엔씨 |
가교제 및 그 용도
|
|
NZ589880A
(en)
|
2008-06-16 |
2012-10-26 |
Immunogen Inc |
Use of synergistic anti-cancer compositions comprising lenalidomide, at least one corticosteroid and at least one immunoconjugate
|
|
GB0813432D0
(en)
|
2008-07-22 |
2008-08-27 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
GB0819095D0
(en)
|
2008-10-17 |
2008-11-26 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
GB0819097D0
(en)
|
2008-10-17 |
2008-11-26 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
IL271761B
(en)
|
2009-02-05 |
2022-09-01 |
Immunogen Inc |
(12as)-8-methoxy-9-benzyloxy-11,12,12a,13-tetrahydro-6h-indolo[2,1-c][1,4]benzodiazepin-6-one, 4-benzyloxy-5-methoxy-2-nitrobenzoic acid and processes for preparing the same
|
|
CN102421800A
(zh)
|
2009-02-23 |
2012-04-18 |
格兰马克药品股份有限公司 |
结合cd19的人源化抗体及其用途
|
|
JP5382792B2
(ja)
|
2009-08-14 |
2014-01-08 |
独立行政法人理化学研究所 |
光2次非線形薄膜における1次及び2次光感受率異方性同時測定方法、当該方法を実行する装置及び当該方法をコンピュータに実行させるプログラム
|
|
FR2949469A1
(fr)
|
2009-08-25 |
2011-03-04 |
Sanofi Aventis |
Derives anticancereux, leur preparation et leur application en therapeutique
|
|
CN102612524A
(zh)
|
2009-09-01 |
2012-07-25 |
雅培制药有限公司 |
双重可变结构域免疫球蛋白及其用途
|
|
JP2013505944A
(ja)
|
2009-09-24 |
2013-02-21 |
シアトル ジェネティックス, インコーポレイテッド |
Dr5リガンド薬物結合体
|
|
ES2449379T3
(es)
|
2010-02-09 |
2014-03-19 |
Bristol-Myers Squibb Company |
Derivados de bencilpirrolidinona como moduladores de la actividad de receptores de quimiocinas
|
|
WO2011100398A1
(en)
|
2010-02-10 |
2011-08-18 |
Immunogen, Inc. |
Cd20 antibodies and uses thereof
|
|
RU2573994C2
(ru)
|
2010-02-10 |
2016-01-27 |
Иммьюноджен, Инк |
Антитела против cd20 и их применение
|
|
MX2012011900A
(es)
|
2010-04-15 |
2013-03-21 |
Seattle Genetics Inc |
Conjugados de pirrolobenzodiazepina diana.
|
|
WO2011130615A2
(en)
|
2010-04-15 |
2011-10-20 |
Dr. Reddy's Laboratories Ltd. |
Preparation of lacosamide
|
|
NZ602241A
(en)
|
2010-04-15 |
2015-03-27 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
|
EP2558475A1
(en)
*
|
2010-04-15 |
2013-02-20 |
Spirogen Sàrl |
Pyrrolobenzodiazepines used to treat proliferative diseases
|
|
GB201006340D0
(en)
|
2010-04-15 |
2010-06-02 |
Spirogen Ltd |
Synthesis method and intermediates
|
|
PT2560645T
(pt)
|
2010-04-21 |
2016-10-24 |
Syntarga Bv |
Conjugados de análogos de cc-1065 e ligantes bifuncionais
|
|
FR2963007B1
(fr)
|
2010-07-26 |
2013-04-05 |
Sanofi Aventis |
Derives anticancereux, leur preparation et leur application therapeutique
|
|
CN113896731A
(zh)
|
2011-02-15 |
2022-01-07 |
伊缪诺金公司 |
细胞毒性苯并二氮杂䓬衍生物
|
|
US9135118B2
(en)
|
2011-03-07 |
2015-09-15 |
Aptare, Inc. |
System to catalog and search point-in-time instances of a file system
|
|
KR101860174B1
(ko)
|
2011-09-20 |
2018-05-21 |
메디뮨 리미티드 |
표적 접합체 내의 내포를 위한 비대칭 이량체 pbd 화합물로서 피롤로벤조디아제핀
|
|
BR112014009070B1
(pt)
|
2011-10-14 |
2021-11-23 |
Medimmune Limited |
Método de síntese e intermediários úteis na preparação de pirrolobenzo-diazepinas
|
|
BR112014008888A2
(pt)
|
2011-10-14 |
2017-04-18 |
Seattle Genetics Inc |
pirrolobenzodiazepinas
|
|
PL2750713T3
(pl)
|
2011-10-14 |
2016-03-31 |
Medimmune Ltd |
Pirolobenzodiazepiny i ich koniugaty
|
|
CN103998449A
(zh)
|
2011-10-14 |
2014-08-20 |
斯皮罗根有限公司 |
吡咯并苯并二氮杂卓
|
|
CN103987384A
(zh)
|
2011-10-14 |
2014-08-13 |
西雅图基因公司 |
吡咯并苯并二氮杂卓和靶向结合物
|
|
CN103997893B
(zh)
|
2011-10-14 |
2019-04-12 |
西雅图基因公司 |
吡咯并苯并二氮杂卓和靶向结合物
|
|
JP2013194140A
(ja)
|
2012-03-19 |
2013-09-30 |
Fuji Xerox Co Ltd |
トナー用ポリエステル樹脂、静電荷像現像用トナー、静電荷像現像剤、トナーカートリッジ、プロセスカートリッジ、画像形成装置及び画像形成方法
|
|
CN104540827B
(zh)
|
2012-04-30 |
2018-03-23 |
Ucl商业有限公司 |
吡咯并苯并二氮杂卓
|
|
JP6157596B2
(ja)
|
2012-04-30 |
2017-07-05 |
メドイミューン・リミテッドMedImmune Limited |
ピロロベンゾジアゼピン
|
|
WO2013177481A1
(en)
|
2012-05-25 |
2013-11-28 |
Immunogen, Inc. |
Benzodiazepines and conjugates thereof
|
|
CA2873884A1
(en)
|
2012-07-09 |
2014-01-16 |
Genentech, Inc. |
Immunoconjugates comprising anti-cd79b antibodies
|
|
HK1209043A1
(en)
|
2012-07-09 |
2016-03-24 |
基因泰克公司 |
Immunoconjugates comprising anti-cd22 antibodies
|
|
CN104717979A
(zh)
|
2012-08-02 |
2015-06-17 |
基因泰克公司 |
抗etbr抗体和免疫偶联物
|
|
EP2887965A1
(en)
|
2012-08-22 |
2015-07-01 |
ImmunoGen, Inc. |
Cytotoxic benzodiazepine derivatives
|
|
JP2016502504A
(ja)
|
2012-10-12 |
2016-01-28 |
エイディーシー・セラピューティクス・エス・アー・エール・エルAdc Therapeutics Sarl |
ピロロベンゾジアゼピン−抗体結合体
|
|
US10736903B2
(en)
|
2012-10-12 |
2020-08-11 |
Medimmune Limited |
Pyrrolobenzodiazepine-anti-PSMA antibody conjugates
|
|
US9931415B2
(en)
|
2012-10-12 |
2018-04-03 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
|
WO2014057120A1
(en)
|
2012-10-12 |
2014-04-17 |
Adc Therapeutics Sàrl |
Pyrrolobenzodiazepine-antibody conjugates
|
|
JP6367204B2
(ja)
|
2012-10-12 |
2018-08-01 |
メドイミューン・リミテッドMedImmune Limited |
結合用のピロロベンゾジアゼピン誘導体の合成および中間体
|
|
HRP20181646T2
(hr)
*
|
2012-10-12 |
2019-08-09 |
Adc Therapeutics Sa |
Konjugati pirolobenzodiazepin - anti-psma protutijela
|
|
HRP20171916T1
(hr)
|
2012-10-12 |
2018-02-09 |
Adc Therapeutics Sa |
Konjugati protutijelo anti-cd22 - pirolobenzodiazepin
|
|
PT3470086T
(pt)
|
2012-10-12 |
2021-02-01 |
Medimmune Ltd |
Pirrolobenzodiazepinas e conjugados das mesmas
|
|
WO2014057118A1
(en)
|
2012-10-12 |
2014-04-17 |
Adc Therapeutics Sarl |
Pyrrolobenzodiazepine-anti-cd22 antibody conjugates
|
|
CA2885340C
(en)
|
2012-10-12 |
2016-11-08 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
|
SMT201900017T1
(it)
|
2012-10-12 |
2019-02-28 |
Medimmune Ltd |
Coniugati pirrolobenzodiazepina-anticorpo
|
|
US10131682B2
(en)
|
2012-11-24 |
2018-11-20 |
Hangzhou Dac Biotech Co., Ltd. |
Hydrophilic linkers and their uses for conjugation of drugs to a cell binding molecules
|
|
AU2013366490B9
(en)
|
2012-12-21 |
2018-02-01 |
Medimmune Limited |
Unsymmetrical pyrrolobenzodiazepines-dimers for use in the treatment of proliferative and autoimmune diseases
|
|
BR112015014669B1
(pt)
|
2012-12-21 |
2023-09-26 |
Medimmune Limited |
Compostos pirrolobenzodiazepinas, conjugados compreendendo os mesmos e uso destes para tratar uma doença proliferativa
|
|
KR20160037130A
(ko)
|
2013-02-22 |
2016-04-05 |
스템센트알엑스 인코포레이티드 |
신규한 항체 접합체 및 이의 용도
|
|
NZ712035A
(en)
|
2013-03-13 |
2019-06-28 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
|
CN105142674B
(zh)
|
2013-03-13 |
2018-11-13 |
麦迪穆有限责任公司 |
吡咯并苯并二氮杂卓和其结合物
|
|
EA027910B1
(ru)
|
2013-03-13 |
2017-09-29 |
Медимьюн Лимитед |
Пирролобензодиазепины и их конъюгаты
|
|
JP2016518382A
(ja)
|
2013-04-26 |
2016-06-23 |
ピエール、ファーブル、メディカマン |
Axl抗体薬物複合体および癌の治療のためのその使用
|
|
NL2011583C2
(en)
|
2013-10-10 |
2015-04-13 |
Wwinn B V |
Module, system and method for detecting acoustical failure of a sound source.
|
|
GB201317981D0
(en)
|
2013-10-11 |
2013-11-27 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
|
EP3054986B1
(en)
|
2013-10-11 |
2019-03-20 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
|
WO2015052533A1
(en)
|
2013-10-11 |
2015-04-16 |
Spirogen Sàrl |
Pyrrolobenzodiazepine-antibody conjugates
|
|
GB201318069D0
(en)
|
2013-10-11 |
2013-11-27 |
Maersk Olie & Gas |
Seismic data processing method and apparatus
|
|
GB201317982D0
(en)
|
2013-10-11 |
2013-11-27 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
|
EP3054983B1
(en)
|
2013-10-11 |
2019-03-20 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
|
EP3054985B1
(en)
|
2013-10-11 |
2018-12-26 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
|
AU2014333776B2
(en)
|
2013-10-11 |
2021-01-28 |
Cellectis |
Methods and kits for detecting nucleic acid sequences of interest using DNA-binding protein domain
|
|
DE102013220528B4
(de)
|
2013-10-11 |
2015-05-07 |
Continental Automotive Gmbh |
Einspritzventil und Verfahren zum Betreiben eines Einspritzventils
|
|
HK1222577A1
(zh)
|
2013-12-16 |
2017-07-07 |
Genentech Inc. |
擬肽化合物及其抗體藥物偶聯物
|
|
GB201406767D0
(en)
|
2014-04-15 |
2014-05-28 |
Cancer Rec Tech Ltd |
Humanized anti-Tn-MUC1 antibodies anf their conjugates
|
|
US10188746B2
(en)
|
2014-09-10 |
2019-01-29 |
Medimmune Limited |
Pyrrolobenzodiazepines and conjugates thereof
|
|
GB201416112D0
(en)
|
2014-09-12 |
2014-10-29 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
|
AU2015314744A1
(en)
|
2014-09-12 |
2017-03-02 |
Genentech, Inc. |
Anti-CLL-1 antibodies and immunoconjugates
|
|
CR20170099A
(es)
|
2014-09-17 |
2017-07-19 |
Genentech Inc |
Pirrolobenzodiazepinas y conjugados de anticuerpos-disulfuro de las mismas
|