JP2020500906A5 - - Google Patents

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JP2020500906A5
JP2020500906A5 JP2019530713A JP2019530713A JP2020500906A5 JP 2020500906 A5 JP2020500906 A5 JP 2020500906A5 JP 2019530713 A JP2019530713 A JP 2019530713A JP 2019530713 A JP2019530713 A JP 2019530713A JP 2020500906 A5 JP2020500906 A5 JP 2020500906A5
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compound
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formula
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JP6916285B2 (ja
JP2020500906A (ja
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Priority claimed from PCT/US2017/065425 external-priority patent/WO2018107100A1/en
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Priority to JP2021075890A priority Critical patent/JP7373522B2/ja
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Priority to JP2023132080A priority patent/JP2023154048A/ja
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JP2019530713A 2016-12-09 2017-12-08 嚢胞性線維症膜コンダクタンス制御因子の調節物質、医薬組成物、治療方法、及び調節物質の作製プロセス Active JP6916285B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2021075890A JP7373522B2 (ja) 2016-12-09 2021-04-28 嚢胞性線維症膜コンダクタンス制御因子の調節物質、医薬組成物、治療方法、及び調節物質の作製プロセス
JP2023132080A JP2023154048A (ja) 2016-12-09 2023-08-14 嚢胞性線維症膜コンダクタンス制御因子の調節物質、医薬組成物、治療方法、及び調節物質の作製プロセス

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662432537P 2016-12-09 2016-12-09
US62/432,537 2016-12-09
PCT/US2017/065425 WO2018107100A1 (en) 2016-12-09 2017-12-08 Modulator of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulator

Related Child Applications (1)

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JP2021075890A Division JP7373522B2 (ja) 2016-12-09 2021-04-28 嚢胞性線維症膜コンダクタンス制御因子の調節物質、医薬組成物、治療方法、及び調節物質の作製プロセス

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JP2020500906A JP2020500906A (ja) 2020-01-16
JP2020500906A5 true JP2020500906A5 (https=) 2021-01-07
JP6916285B2 JP6916285B2 (ja) 2021-08-11

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JP2019530713A Active JP6916285B2 (ja) 2016-12-09 2017-12-08 嚢胞性線維症膜コンダクタンス制御因子の調節物質、医薬組成物、治療方法、及び調節物質の作製プロセス
JP2021075890A Active JP7373522B2 (ja) 2016-12-09 2021-04-28 嚢胞性線維症膜コンダクタンス制御因子の調節物質、医薬組成物、治療方法、及び調節物質の作製プロセス
JP2023132080A Pending JP2023154048A (ja) 2016-12-09 2023-08-14 嚢胞性線維症膜コンダクタンス制御因子の調節物質、医薬組成物、治療方法、及び調節物質の作製プロセス

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JP2021075890A Active JP7373522B2 (ja) 2016-12-09 2021-04-28 嚢胞性線維症膜コンダクタンス制御因子の調節物質、医薬組成物、治療方法、及び調節物質の作製プロセス
JP2023132080A Pending JP2023154048A (ja) 2016-12-09 2023-08-14 嚢胞性線維症膜コンダクタンス制御因子の調節物質、医薬組成物、治療方法、及び調節物質の作製プロセス

Country Status (37)

Country Link
US (4) US10793547B2 (https=)
EP (2) EP3551622B1 (https=)
JP (3) JP6916285B2 (https=)
KR (1) KR102269492B1 (https=)
CN (2) CN110267948B (https=)
AR (1) AR110346A1 (https=)
AU (3) AU2017371200B2 (https=)
CA (1) CA3046086A1 (https=)
CL (1) CL2019001553A1 (https=)
CO (1) CO2019007129A2 (https=)
CY (1) CY1123736T1 (https=)
DK (1) DK3551622T3 (https=)
EA (2) EA039280B1 (https=)
EC (1) ECSP19048759A (https=)
ES (1) ES2837431T3 (https=)
GE (1) GEP20247634B (https=)
HR (1) HRP20201946T1 (https=)
HU (1) HUE052205T2 (https=)
IL (3) IL294237A (https=)
JO (1) JOP20190125B1 (https=)
LT (1) LT3551622T (https=)
MA (2) MA54847A (https=)
MD (1) MD3551622T2 (https=)
MX (2) MX388103B (https=)
NZ (1) NZ795112A (https=)
PE (2) PE20241131A1 (https=)
PT (1) PT3551622T (https=)
RS (1) RS61150B1 (https=)
SA (1) SA519401947B1 (https=)
SG (1) SG10201913606VA (https=)
SI (1) SI3551622T1 (https=)
SM (1) SMT202000617T1 (https=)
TW (1) TWI774712B (https=)
UA (1) UA128449C2 (https=)
UY (2) UY37513A (https=)
WO (1) WO2018107100A1 (https=)
ZA (2) ZA201904062B (https=)

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US12324802B2 (en) 2020-11-18 2025-06-10 Vertex Pharmaceuticals Incorporated Modulators of cystic fibrosis transmembrane conductance regulator
KR20230118123A (ko) 2020-12-10 2023-08-10 버텍스 파마슈티칼스 인코포레이티드 낭성 섬유증 치료 방법
CA3249865A1 (en) 2022-02-03 2023-08-10 Vertex Pharmaceuticals Incorporated PROCESSES FOR PREPARATION AND CRYSTALLINE FORMS OF (6A,12A)-17-AMINO-12-METHYL-6,15-BIS(TRIFLUOROMETHYL)-13,19-DIOXA-3,4,18-TRIAZATRICYCLO[12,3,1,12,5]NONADECA-1(18),2,4,14,16-PENTAEN-6-OL
JP2025506382A (ja) 2022-02-03 2025-03-11 バーテックス ファーマシューティカルズ インコーポレイテッド 嚢胞性線維症の治療方法
JP2025505643A (ja) 2022-02-08 2025-02-28 バーテックス ファーマシューティカルズ インコーポレイテッド 嚢胞性線維症膜コンダクタンス制御因子の調節因子
JP2025517323A (ja) 2022-05-16 2025-06-05 バーテックス ファーマシューティカルズ インコーポレイテッド Cftrモジュレーターとしての大環状化合物の固体形態及びその調製
WO2023224931A1 (en) 2022-05-16 2023-11-23 Vertex Pharmaceuticals Incorporated Methods of treatment for cystic fibrosis
IL317522A (en) * 2022-06-10 2025-02-01 Sionna Therapeutics Inc Compounds, preparations and methods of using them
US20260034064A1 (en) 2022-08-04 2026-02-05 Vertex Pharmaceuticals Incorporated Compositions for the treatment of cftr-mediated diseases
WO2024056798A1 (en) 2022-09-15 2024-03-21 Idorsia Pharmaceuticals Ltd Macrocyclic cftr modulators
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WO2021030552A1 (en) 2019-08-14 2021-02-18 Vertex Pharmaceuticals Incorporated Crystalline forms of cftr modulators
TWI867024B (zh) 2019-08-14 2024-12-21 美商維泰克斯製藥公司 囊腫纖維化跨膜傳導調節蛋白之調節劑
TWI899097B (zh) 2019-08-14 2025-10-01 美商維泰克斯製藥公司 製備cftr調節劑之方法
US20220313698A1 (en) 2019-08-14 2022-10-06 Vertex Pharmaceuticals Incorporated Modulators of cystic fibrosis transmembrane conductance regulator

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