|
US20110229471A1
(en)
|
2008-11-26 |
2011-09-22 |
Cedars-Sinai Medical Center |
Methods of determining responsiveness to anti-tnf alpha therapy in inflammatory bowel disease
|
|
US9828582B2
(en)
|
2013-03-19 |
2017-11-28 |
Duke University |
Compositions and methods for the induction and tuning of gene expression
|
|
KR20230109779A
(ko)
|
2013-03-27 |
2023-07-20 |
세다르스-신나이 메디칼 센터 |
Tl1a 기능 및 관련된 신호전달 경로의 저해에 의한섬유증 및 염증의 완화 및 반전
|
|
EP3022295A4
(en)
|
2013-07-19 |
2017-03-01 |
Cedars-Sinai Medical Center |
Signature of tl1a (tnfsf15) signaling pathway
|
|
WO2016130600A2
(en)
|
2015-02-09 |
2016-08-18 |
Duke University |
Compositions and methods for epigenome editing
|
|
KR102787119B1
(ko)
|
2015-11-30 |
2025-03-27 |
듀크 유니버시티 |
유전자 편집에 의한 인간 디스트로핀 유전자의 교정을 위한 치료용 표적 및 사용 방법
|
|
EP3390669B1
(en)
*
|
2015-12-20 |
2024-07-31 |
The National Institute for Biotechnology in the Negev, Ltd. |
Biomarkers of chronic lymphocytic leukemia and use thereof
|
|
WO2017112921A1
(en)
*
|
2015-12-24 |
2017-06-29 |
The Arizona Board Of Regents On Behalf Of The University Of Arizona |
Systems and methods for characterizing sepsis
|
|
US11492386B2
(en)
*
|
2016-02-01 |
2022-11-08 |
Eli Lilly And Company |
Parathyroid hormone-anti-RANKL antibody fusion compounds
|
|
KR20240095481A
(ko)
|
2016-03-17 |
2024-06-25 |
세다르스-신나이 메디칼 센터 |
Rnaset2를 통한 염증성 장 질환의 진단 방법
|
|
JP2019513371A
(ja)
|
2016-04-01 |
2019-05-30 |
アビディティー バイオサイエンシーズ エルエルシー |
核酸ポリペプチド組成物とその使用
|
|
US20190127713A1
(en)
|
2016-04-13 |
2019-05-02 |
Duke University |
Crispr/cas9-based repressors for silencing gene targets in vivo and methods of use
|
|
EP3458466B1
(en)
|
2016-05-20 |
2024-08-07 |
Cedars-Sinai Medical Center |
Diagnosis of inflammatory bowel disease based on genes
|
|
GB201611738D0
(en)
|
2016-07-05 |
2016-08-17 |
Cambridge Entpr Ltd |
Biomarkers for inflammatory bowel disease
|
|
JP7490211B2
(ja)
|
2016-07-19 |
2024-05-27 |
デューク ユニバーシティ |
Ｃｐｆ１に基づくゲノム編集の治療適用
|
|
UY37376A
(es)
*
|
2016-08-26 |
2018-03-23 |
Amgen Inc |
Construcciones de arni para inhibir expresión de asgr1 y métodos para su uso
|
|
EP3327134A1
(en)
*
|
2016-11-28 |
2018-05-30 |
Carsten Korth |
Method and biomarkers for in vitro diagnosis of mental disorders
|
|
CN106834288B
(zh)
*
|
2016-12-16 |
2020-08-21 |
南京医科大学 |
一种长非编码rna及其在诊断/治疗胃癌中的应用
|
|
MX2019008199A
(es)
|
2017-01-06 |
2019-11-25 |
Avidity Biosciences Llc |
Composiciones de acido nucleico polipeptido y metodos de induccion de la omision de exon.
|
|
CN106929508B
(zh)
*
|
2017-02-17 |
2020-08-21 |
张灏 |
一种激活PTPRO基因表达的saRNA及其转运载体
|
|
US11306311B2
(en)
*
|
2017-06-08 |
2022-04-19 |
Chandrasekhar Kanduri |
Long non-coding RNA in cancer
|
|
GB201709866D0
(en)
*
|
2017-06-20 |
2017-08-02 |
Immunocore Ltd |
T cell receptors
|
|
US10392616B2
(en)
*
|
2017-06-30 |
2019-08-27 |
Arbor Biotechnologies, Inc. |
CRISPR RNA targeting enzymes and systems and uses thereof
|
|
GB201711809D0
(en)
|
2017-07-21 |
2017-09-06 |
Governors Of The Univ Of Alberta |
Antisense oligonucleotide
|
|
WO2019051312A1
(en)
*
|
2017-09-07 |
2019-03-14 |
University Of Massachusetts |
THERAPY AGAINST SELENIUM CANCER
|
|
US20200208152A1
(en)
|
2017-09-08 |
2020-07-02 |
Mina Therapeutics Limited |
Stabilized sarna compositions and methods of use
|
|
US20210130776A1
(en)
*
|
2017-09-29 |
2021-05-06 |
The Broad Institute, Inc. |
Methods and compositions for modulating suppression of lymphocyte activity
|
|
JP7277460B2
(ja)
|
2017-11-30 |
2023-05-19 |
マヨ ファウンデーション フォア メディカル エデュケーション アンド リサーチ |
乳癌の検出
|
|
KR102723989B1
(ko)
*
|
2017-12-01 |
2024-11-01 |
더 텍사스 에이 & 엠 유니버시티 시스템 |
엔젤만 증후군 안티센스 치료
|
|
CN107988223B
(zh)
*
|
2017-12-06 |
2021-08-13 |
张灏 |
一种激活PTPRO基因表达的saRNA及其在肿瘤干细胞治疗中的应用
|
|
AU2018378812B2
(en)
|
2017-12-06 |
2025-05-22 |
Avidity Biosciences, Inc. |
Compositions and methods of treating muscle atrophy and myotonic dystrophy
|
|
EP3720508A4
(en)
*
|
2017-12-08 |
2021-09-01 |
University of Connecticut |
COMPOSITIONS AND METHODS FOR TREATMENT OF GENOMIC FOOTPRINT DISORDERS
|
|
CN108130368B
(zh)
*
|
2017-12-21 |
2021-12-14 |
中国医学科学院北京协和医院 |
lncRNA在制备诊断或预示青少年特发性脊柱侧凸产品中的应用
|
|
CN108085389B
(zh)
*
|
2017-12-29 |
2020-06-09 |
青岛泱深生物医药有限公司 |
一种与乳腺癌相关的lncRNA及其应用
|
|
CN107937550B
(zh)
*
|
2018-01-08 |
2020-06-02 |
青岛泱深生物医药有限公司 |
一种与乳腺癌发生发展相关的生物标志物及其应用
|
|
EP3740580A4
(en)
|
2018-01-19 |
2021-10-20 |
Duke University |
GENOME ENGINEERING WITH CRISPR-CAS SYSTEMS IN EUKARYONTS
|
|
EP3735248A4
(en)
*
|
2018-02-09 |
2021-11-17 |
Empirico Inc. |
PROCESS FOR INHIBITED OR ELIMINATING EOSINOPHILIC DISEASES OF THE RESPIRATORY TRACT AND ASSOCIATED CONDITIONS
|
|
PH12020551219A1
(en)
|
2018-02-14 |
2021-04-19 |
Deep Genomics Incorporated |
Oligonucleotide therapy for wilson disease
|
|
MA51869A
(fr)
*
|
2018-02-16 |
2020-12-23 |
Bayer Healthcare Llc |
Compositions et méthodes pour l'édition génique par ciblage du fibrinogène-alpha
|
|
MX2020008581A
(es)
|
2018-02-21 |
2020-09-21 |
Bristol Myers Squibb Co |
Oligonucleotidos antisentido de la proteina cinasa del tipo ii delta dependiente del calcio/calmodulina (camk2d) y sus usos.
|
|
CN108192973B
(zh)
*
|
2018-03-02 |
2021-06-04 |
中南大学湘雅医院 |
长链非编码rna linc00559作为生物标志物在制备肺腺癌预后检测制剂中的应用
|
|
CN108192974B
(zh)
*
|
2018-03-02 |
2021-11-05 |
中南大学湘雅医院 |
长链非编码rna linc00842作为生物标志物在制备肺腺癌预后检测制剂中的应用
|
|
CN108192976B
(zh)
*
|
2018-03-02 |
2021-06-04 |
中南大学湘雅医院 |
长链非编码rna linc00336作为生物标志物在制备肺鳞癌预后检测制剂中的应用
|
|
CN108192975B
(zh)
*
|
2018-03-02 |
2021-06-04 |
中南大学湘雅医院 |
长链非编码rna linc00559作为生物标志物在制备肺鳞癌预后检测制剂中的应用
|
|
US20210332366A1
(en)
*
|
2018-04-10 |
2021-10-28 |
Ractigen Therapeutics |
Novel Small Activating RNA
|
|
EP3775211B1
(en)
*
|
2018-04-12 |
2023-04-05 |
MiNA Therapeutics Limited |
Sirt1-sarna compositions and methods of use
|
|
CN110468200B
(zh)
*
|
2018-05-10 |
2023-02-28 |
复旦大学附属肿瘤医院 |
一种用于癌症预后的多基因检测试剂盒
|
|
EP3801028A4
(en)
|
2018-05-30 |
2022-04-13 |
Direct Biologics LLC |
A growth factor and extracellular vesicle frozen or powdered additive comprising a mesenchymal stem cell (msc) preparation and methods of use
|
|
GB2589224A
(en)
*
|
2018-06-01 |
2021-05-26 |
Childrens Nat Medical Ct |
Compositions and methods for treating and preventing muscular disorders and dystrophies, steroid side effects, and inflammation
|
|
CN108424969B
(zh)
*
|
2018-06-06 |
2022-07-15 |
深圳市颐康生物科技有限公司 |
一种生物标志物、诊断或预估死亡风险的方法
|
|
EP3813844A1
(en)
*
|
2018-06-28 |
2021-05-05 |
United Kingdom Research and Innovation |
Treatment of cardiomyopathy through modulation of hypoxia-induced erna activity
|
|
JP7571005B2
(ja)
*
|
2018-08-04 |
2024-10-22 |
インペリアル・カレッジ・イノベーションズ・リミテッド |
川崎病を患う対象を特定する方法
|
|
CN109097464B
(zh)
*
|
2018-09-19 |
2021-12-14 |
中国医学科学院阜外医院深圳医院(深圳市孙逸仙心血管医院) |
Cfap43基因的snp位点的应用
|
|
CN109097465B
(zh)
*
|
2018-09-19 |
2021-06-08 |
蒲佐 |
Clip3基因的snp位点的应用
|
|
US12097239B2
(en)
|
2018-09-21 |
2024-09-24 |
President And Fellows Of Harvard College |
Methods and compositions for treating diabetes, and methods for enriching MRNA coding for secreted proteins
|
|
IL281470B2
(en)
|
2018-09-28 |
2025-08-01 |
Harvard College |
Cellular reprogramming to reverse aging and promote organ and tissue regeneration
|
|
US12274733B2
(en)
|
2018-09-28 |
2025-04-15 |
President And Fellows Of Harvard College |
Cellular reprogramming to reverse aging and promote organ and tissue regeneration
|
|
CN109182503B
(zh)
*
|
2018-09-28 |
2021-09-28 |
新乡医学院 |
动脉粥样硬化分子标志物及其应用
|
|
CN111020029B
(zh)
*
|
2018-10-10 |
2023-09-29 |
江苏普瑞悉恩生物科技有限公司 |
实时荧光定量pcr检测pd-l1基因表达量的方法、引物及试剂盒
|
|
US20210383924A1
(en)
*
|
2018-10-25 |
2021-12-09 |
Quadrant Biosciences Inc. |
Methods and machine learning for disease diagnosis
|
|
US20210395738A1
(en)
|
2018-11-08 |
2021-12-23 |
Greenlight Biosciences, Inc. |
Control of insect infestation
|
|
CN109207598A
(zh)
*
|
2018-11-09 |
2019-01-15 |
汕头大学医学院附属肿瘤医院 |
一种长链非编码rna在制备食管癌诊断试剂或治疗药物中的应用
|
|
CA3119749A1
(en)
*
|
2018-11-15 |
2020-05-22 |
Ampel Biosolutions, Llc |
Machine learning disease prediction and treatment prioritization
|
|
WO2020117706A1
(en)
|
2018-12-03 |
2020-06-11 |
Triplet Therapeutics, Inc. |
Methods for the treatment of trinucleotide repeat expansion disorders associated with mlh3 activity
|
|
CN109355391A
(zh)
*
|
2018-12-05 |
2019-02-19 |
山东省千佛山医院 |
Linc01876作为诊断肝癌的分子标志物的应用
|
|
CN110093348B
(zh)
*
|
2018-12-05 |
2022-11-29 |
西北工业大学 |
增强小鼠NPFFR2基因表达的shRNA
|
|
WO2020117840A2
(en)
*
|
2018-12-05 |
2020-06-11 |
Empirico Inc. |
Process to inhibit or eliminate eosinophilic diseases of the airway and related conditions
|
|
CN113227375A
(zh)
|
2018-12-20 |
2021-08-06 |
原住民股份有限公司 |
合成的微小rna模拟物
|
|
IL312067B2
(en)
|
2018-12-21 |
2025-08-01 |
Avidity Biosciences Inc |
Anti-transferrin receptor antibodies and uses thereof
|
|
PE20212248A1
(es)
*
|
2018-12-29 |
2021-11-24 |
Ractigen Therapeutics |
Molecula oligomerica de acido nucleico y uso de esta
|
|
CN109813912B
(zh)
*
|
2019-01-04 |
2021-12-28 |
深圳大学 |
一组血清差异蛋白组合在制备用于检测孤独症的试剂中的应用
|
|
CN109837336B
(zh)
*
|
2019-01-09 |
2022-07-19 |
中国人民解放军军事科学院军事医学研究院 |
辐射敏感基因标记物及在鉴别高let射线辐射中的应用
|
|
CN109652532A
(zh)
*
|
2019-01-11 |
2019-04-19 |
中国人民解放军总医院 |
一种检测心血管系统用药的标志物
|
|
WO2020150606A1
(en)
*
|
2019-01-18 |
2020-07-23 |
The General Hospital Corporation |
Methods and compositions for modulating immune dysregulation
|
|
KR102162847B1
(ko)
*
|
2019-01-23 |
2020-10-07 |
차의과학대학교 산학협력단 |
요로결석 진단을 위한 분석방법 및 키트
|
|
KR20210131322A
(ko)
*
|
2019-01-24 |
2021-11-02 |
락티젠 세러퓨틱스 |
피부 보호용 올리고머 핵산
|
|
JP2022529562A
(ja)
*
|
2019-01-30 |
2022-06-23 |
ラクティゲン セラピューティクス |
オリゴヌクレオチド分子及び腫瘍治療におけるその応用
|
|
US12569517B2
(en)
|
2019-02-07 |
2026-03-10 |
Direct Biologics, Llc |
Method for treating osteoarthritis with mesenchymal stem cell exosomes
|
|
WO2020172338A1
(en)
*
|
2019-02-19 |
2020-08-27 |
Whitehead Institute For Biomedical Research |
Methods and agents for modulating mitochondrial nad levels
|
|
JP7224690B2
(ja)
*
|
2019-03-07 |
2023-02-20 |
レチ マーク カンパニー リミテッド |
糖尿病網膜症の診断用複合マーカーおよびその用途
|
|
US12595479B2
(en)
*
|
2019-03-20 |
2026-04-07 |
President And Fellows Of Harvard College |
Antisense oligonucleotide-based progranulin augmentation therapy in neurodegenerative diseases
|
|
KR20200113556A
(ko)
*
|
2019-03-25 |
2020-10-07 |
황인후 |
St8sia1를 이용한 당뇨병의 예방 또는 치료용 조성물과 당뇨병 치료제 스크리닝 방법
|
|
EP3947735A4
(en)
*
|
2019-03-25 |
2022-12-28 |
The Board Of Trustees Of The Leland Stanford Junior University |
SIGNATURE FOR DIAGNOSIS OF BACTERIAL VS VIRAL INFECTIONS
|
|
CN109880828B
(zh)
*
|
2019-03-26 |
2021-02-05 |
河南师范大学 |
干扰Mroh7基因表达的siRNA及其应用、干扰方法与药物
|
|
EP3947700A4
(en)
|
2019-04-01 |
2023-01-04 |
Tenaya Therapeutics, Inc. |
Adeno-associated virus with engineered capsid
|
|
EP3956448A4
(en)
*
|
2019-04-18 |
2022-10-19 |
University of Massachusetts |
AIM2 INHIBITORS AND USES THEREOF
|
|
WO2020219820A1
(en)
|
2019-04-25 |
2020-10-29 |
Avidity Biosciences, Inc. |
Nucleic acid compositions and methods of multi-exon skipping
|
|
CN111849968A
(zh)
*
|
2019-04-30 |
2020-10-30 |
中美瑞康核酸技术(南通)研究院有限公司 |
寡核苷酸分子及其在急性间歇性卟啉症治疗中的应用
|
|
EP3965777A4
(en)
*
|
2019-05-06 |
2024-08-07 |
The Children's Hospital of Philadelphia |
MICRORNA SITE-BLOCKING OLIGONUCLEOTIDES FOR THE TREATMENT OF EPILEPTIC ENCEPHALOPATHY AND NEURODEVELOPMENTAL DISORDERS
|
|
WO2020227713A1
(en)
*
|
2019-05-09 |
2020-11-12 |
The Children's Hospital Of Philadelphia |
Compositions and methods for the treatment of leukodystrophy and whole animal and cellular models for the identifying efficacious agents for treatment of the same
|
|
CN110079601B
(zh)
*
|
2019-05-23 |
2022-04-19 |
青岛市中心医院 |
放射性相关疾病诊疗标志物及其应用
|
|
CN110106180B
(zh)
*
|
2019-05-29 |
2020-10-16 |
中国医科大学附属盛京医院 |
一种lncRNA分子及其在胶质瘤治疗/预后评估中的应用
|
|
GB201907882D0
(en)
|
2019-06-03 |
2019-07-17 |
Cyprus Foundation For Muscular Dystrophy Res |
Methods
|
|
CN110117659B
(zh)
*
|
2019-06-18 |
2022-10-11 |
上海奕谱生物科技有限公司 |
一种新型的肿瘤标记物stamp-ep10及其应用
|
|
US20230159920A1
(en)
*
|
2019-06-26 |
2023-05-25 |
Fred Hutchinson Cancer Research Center |
Methods and compositions comprising brd9 activating therapies for treating cancers and related disorders
|
|
US12213995B2
(en)
|
2019-07-18 |
2025-02-04 |
Direct Biologics, Llc |
Preparations comprising mesenchymal stem cells and cannabinoids and methods of their use
|
|
CN110577988B
(zh)
*
|
2019-07-19 |
2022-12-20 |
南方医科大学 |
胎儿生长受限的预测模型
|
|
CN110456060B
(zh)
*
|
2019-07-31 |
2022-09-09 |
四川大学华西医院 |
Efcab13自身抗体检测试剂在制备肺癌筛查试剂盒中的用途
|
|
EP4013870A1
(en)
*
|
2019-08-13 |
2022-06-22 |
Alnylam Pharmaceuticals, Inc. |
Small ribosomal protein subunit 25 (rps25) irna agent compositions and methods of use thereof
|
|
US20220281911A1
(en)
|
2019-08-19 |
2022-09-08 |
Mina Therapeutics Limited |
Oligonucleotide conjugate compositions and methods of use
|
|
CN110541027A
(zh)
*
|
2019-08-21 |
2019-12-06 |
昆明医科大学第一附属医院 |
lncRNA HIF1A-AS1抗深静脉血栓的应用
|
|
CN112444627B
(zh)
*
|
2019-09-05 |
2022-03-29 |
四川大学华西医院 |
一种高危胸痛筛查试剂盒
|
|
EP4055175A4
(en)
*
|
2019-11-04 |
2023-11-29 |
Decibel Therapeutics, Inc. |
Cochlear inner hair cell promoters and uses thereof
|
|
JP2023501352A
(ja)
*
|
2019-11-08 |
2023-01-18 |
アイオーニス ファーマシューティカルズ， インコーポレーテッド |
Ｓｐｄｅｆ発現を低減するための化合物及び方法
|
|
CN110876752B
(zh)
*
|
2019-11-18 |
2021-04-30 |
暨南大学 |
长链非编码rna nron功能基序在制备抑制骨吸收及防治骨质疏松药物中的应用
|
|
WO2021113805A1
(en)
*
|
2019-12-05 |
2021-06-10 |
The General Hospital Corporation |
Multi-biomarker prediction models for multiple infection episodes following blunt trauma
|
|
CN111197073A
(zh)
*
|
2019-12-19 |
2020-05-26 |
武汉艾米森生命科技有限公司 |
从粪便中提取dna样本的方法和结直肠癌相关基因的甲基化检测方法
|
|
CN112795579B
(zh)
*
|
2019-12-25 |
2022-03-18 |
四川省人民医院 |
克山病基因筛查试剂盒
|
|
CN113092774B
(zh)
*
|
2020-01-09 |
2022-08-19 |
中国科学院生物物理研究所 |
mtEF4蛋白作为毛发生长和脱发的生物标志物的用途
|
|
CN111118154B
(zh)
*
|
2020-01-16 |
2022-10-18 |
华南协同创新研究院 |
Linc01272在制备肿瘤检测试剂和/或治疗药物中的应用
|
|
CN113134010B
(zh)
*
|
2020-01-20 |
2023-09-01 |
上海市生物医药技术研究院 |
一种靶向雌激素受体α的微小RNA及其抗肿瘤用途
|
|
WO2021151059A1
(en)
*
|
2020-01-24 |
2021-07-29 |
Arizona Board Of Regents On Behalf Of The University Of Arizona |
Compounds and methods for treating or reducing pruritus
|
|
CN111214482B
(zh)
*
|
2020-02-21 |
2022-11-11 |
东莞市第八人民医院（东莞市儿童医院） |
一种靶向linc00467基因的siRNA在白血病耐药性中的应用
|
|
CN111254193A
(zh)
*
|
2020-02-27 |
2020-06-09 |
上海交通大学 |
Dna甲基化标志物pcyt1a在制备诊断pcos试剂盒中的应用
|
|
CN111440867B
(zh)
*
|
2020-03-06 |
2020-12-22 |
河北医科大学第二医院 |
生物标志物在肝癌诊断和治疗中的应用
|
|
CN111394351B
(zh)
*
|
2020-03-18 |
2023-11-07 |
济南爱新卓尔医学检验有限公司 |
一种抑制DICER1-AS1表达的siRNA及其应用
|
|
WO2021188390A1
(en)
|
2020-03-19 |
2021-09-23 |
Avidity Biosciences, Inc. |
Compositions and methods of treating facioscapulohumeral muscular dystrophy
|
|
SI4126066T1
(sl)
|
2020-03-27 |
2026-04-30 |
Avidity Biosciences, Inc. |
Sestavki in postopki zdravljenja mišične distrofije
|
|
KR20230023612A
(ko)
|
2020-04-02 |
2023-02-17 |
마이레큘, 인크. |
조작된 올리고뉴클레오티드를 사용한 표적화된 억제
|
|
CN111424091B
(zh)
*
|
2020-04-20 |
2022-02-08 |
中国医学科学院北京协和医院 |
一组鉴别诊断甲状腺滤泡性肿瘤良恶性的标志物及其应用
|
|
KR20230004709A
(ko)
|
2020-04-22 |
2023-01-06 |
다이렉트 바이오로직스 엘엘씨 |
감염성 질환과 연관된 염증성 병태를 치료하기 위한 방법 및 조성물
|
|
CN111458510B
(zh)
*
|
2020-04-30 |
2020-10-30 |
郑州大学第一附属医院 |
一组早期食管癌和高危人群筛查标志物及相关联检卡
|
|
WO2021231713A2
(en)
|
2020-05-14 |
2021-11-18 |
Ampel Biosolutions, Llc |
Methods and systems for machine learning analysis of single nucleotide polymorphisms in lupus
|
|
EP4153995A4
(en)
*
|
2020-05-19 |
2024-10-23 |
Falcon Bioscience, LLC |
DETECTION AND TREATMENT OF CONDITIONS CHARACTERIZED BY PERFUSION ENGAGEMENT
|
|
CN111562394B
(zh)
*
|
2020-06-02 |
2021-07-02 |
西安交通大学医学院第一附属医院 |
热休克因子2结合蛋白在肝脏缺血再灌注损伤、药物性肝损伤中的应用
|
|
KR20230022167A
(ko)
*
|
2020-06-10 |
2023-02-14 |
락티젠 세러퓨틱스 |
Mitf 유전자를 표적으로 하는 핵산 분자 및 이의 사용
|
|
EP4168549A4
(en)
*
|
2020-06-19 |
2024-10-09 |
Ionis Pharmaceuticals, Inc. |
COMPOUNDS AND METHODS FOR PMP22 MODULATION
|
|
CN111718956B
(zh)
*
|
2020-06-30 |
2022-11-04 |
山东农业大学 |
一种鸡源trim25基因重组荧光表达质粒的制备方法和应用
|
|
CN111593127A
(zh)
*
|
2020-06-30 |
2020-08-28 |
北京泱深生物信息技术有限公司 |
与喉鳞癌密切相关的非编码rna
|
|
CN111910000B
(zh)
*
|
2020-07-02 |
2022-07-01 |
中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） |
一种预测鼻咽癌预后的肿瘤微环境成分标志物组合及系统
|
|
CN111778562A
(zh)
*
|
2020-07-08 |
2020-10-16 |
复旦大学附属华山医院 |
一种用于获取颅颈动脉夹层致病基因突变相关信息的dna文库及应用
|
|
CN112063707B
(zh)
*
|
2020-07-09 |
2022-04-22 |
浙江大学 |
长链非编码rna loc102724238在诊断和治疗原发性翼状胬肉中的应用
|
|
CN113930423B
(zh)
*
|
2020-07-14 |
2024-05-10 |
北京大学 |
保护心肌细胞免受应激损伤的saRNA及其应用
|
|
WO2022015998A1
(en)
*
|
2020-07-15 |
2022-01-20 |
University Of Connecticut |
Gene panels and methods of use thereof for screening and diagnosis of congenital heart defects and diseases
|
|
CN111733249B
(zh)
*
|
2020-07-21 |
2020-12-11 |
北京泱深生物信息技术有限公司 |
喉癌发生发展相关分子标志物
|
|
WO2022022617A1
(en)
*
|
2020-07-31 |
2022-02-03 |
Ractigen Therapeutics |
Combinatory treatment of sma with sarna and mrna modulators
|
|
CN116390759A
(zh)
*
|
2020-08-03 |
2023-07-04 |
卡斯玛治疗公司 |
Tfeb激活和溶酶体生物发生的方法以及用于其的组合物
|
|
WO2022035984A1
(en)
*
|
2020-08-12 |
2022-02-17 |
Skyhawk Therapeutics, Inc. |
Antisense oligonucleotides for treatment of conditions and diseases related to trem2
|
|
CN112094896B
(zh)
*
|
2020-08-27 |
2024-02-09 |
上海市公共卫生临床中心 |
活动性结核病诊断标志物、试剂盒及其应用
|
|
CA3189065A1
(en)
|
2020-09-11 |
2022-03-17 |
Arrowhead Pharmaceuticals, Inc. |
Rnai agents for inhibiting expression of dux4, compositions thereof, and methods of use
|
|
US20230372542A1
(en)
*
|
2020-09-30 |
2023-11-23 |
The Regents Of The University Of California |
Composition and methods for modulating tcf4 gene expession and treating pitt hopkins syndrome
|
|
BR112023006305A2
(pt)
|
2020-10-09 |
2023-05-09 |
Tenaya Therapeutics Inc |
Métodos e composições de terapia gênica com placofilina-2
|
|
CN112143813B
(zh)
*
|
2020-10-28 |
2021-06-29 |
镇江市第一人民医院 |
Prr34-as1作为新型分子标志物及其定量检测方法和应用
|
|
CN112575076A
(zh)
*
|
2020-11-02 |
2021-03-30 |
深圳恒生医院 |
一种用于检测和评估早期自然流产的LncRNA标记物及应用其的产品
|
|
EP4244360A4
(en)
*
|
2020-11-16 |
2025-05-07 |
Beijing SoloBio Genetechnology Company Ltd. |
Recombinant adeno-associated viruses with enhanced liver tropism and uses thereof
|
|
CN112251513B
(zh)
*
|
2020-11-26 |
2023-02-17 |
中国人民解放军总医院第一医学中心 |
一种食管癌和/或胃癌分子标志物Lnc5q31.1、引物、试剂盒及应用
|
|
CN112553199A
(zh)
*
|
2020-11-30 |
2021-03-26 |
深圳市人民医院 |
一种snhg17-KO基因敲除小鼠模型的构建方法和应用
|
|
CN112553333B
(zh)
*
|
2020-12-08 |
2022-03-08 |
南方医科大学深圳医院 |
miR-1207及其靶基因在检测喉鳞癌中的应用
|
|
CN112661826B
(zh)
*
|
2020-12-25 |
2022-03-29 |
中山大学 |
小肽ERpeptide及其在急性髓系白血病中的应用
|
|
CN112641797B
(zh)
*
|
2020-12-30 |
2021-12-17 |
温州医科大学 |
抑制结直肠癌生长、转移的靶标与诊断标志物及其应用
|
|
EP4277999A4
(en)
*
|
2021-01-14 |
2024-12-18 |
Loma Linda University |
METHODS FOR EVALUATION OF EARLY STAGE ORAL SQUAMOUS CELL CARCINOMA
|
|
CN114958844A
(zh)
*
|
2021-01-27 |
2022-08-30 |
青岛市妇女儿童医院 |
一种基因调节剂在抑制口腔癌中的应用
|
|
CN112941076B
(zh)
*
|
2021-02-05 |
2023-07-07 |
中国药科大学 |
FXR靶向的saRNA及其应用
|
|
CN112961914B
(zh)
*
|
2021-02-07 |
2022-08-30 |
安徽省立医院(中国科学技术大学附属第一医院) |
miR-3074-5p作为类风湿关节炎标志物的应用及其试剂盒
|
|
CN112725471B
(zh)
*
|
2021-03-12 |
2022-09-16 |
中国大熊猫保护研究中心 |
野化培训大熊猫免疫适应的分子标记评估方法
|
|
TW202305133A
(zh)
*
|
2021-03-26 |
2023-02-01 |
英商米納治療有限公司 |
Tmem173 sarna組合物及其使用方法
|
|
WO2022212208A1
(en)
*
|
2021-03-29 |
2022-10-06 |
University Of Massachusetts |
Oligonucleotides for syngr-3 modulation
|
|
WO2022215066A1
(en)
*
|
2021-04-05 |
2022-10-13 |
Itayandbiond Ltd |
Small activating rna increasing shank expression and method of treating intellectual disabilities and associated comorbidities associated with shank haploinsufficiency
|
|
CA3214688A1
(en)
|
2021-04-08 |
2022-10-13 |
Andrzej KROLEWSKI |
Methods of diagnosing and predicting renal decline
|
|
WO2022214635A1
(en)
*
|
2021-04-08 |
2022-10-13 |
Stichting Vu |
Nucleic acid molecules for compensation of stxbp1 haploinsufficiency and their use in the treatment of stxbp1-related disorders
|
|
US20240218454A1
(en)
*
|
2021-04-22 |
2024-07-04 |
H. Lee Moffitt Cancer Center And Research Institute, Inc. |
Diagnostic to support clinical trial matching and exploratory biomarker analyses in cancer patients
|
|
WO2022226267A1
(en)
*
|
2021-04-23 |
2022-10-27 |
Alnylam Pharmaceuticals, Inc. |
iRNA COMPOSITIONS AND METHODS FOR SILENCING CHITINASE 3-LIKE PROTEIN 1/YKL-40 (CHI3L1/YKL-40) PROTEIN
|
|
CN112921098B
(zh)
*
|
2021-04-27 |
2023-05-05 |
深圳市人民医院 |
一种用于三阴性乳腺癌检测的标志物及其检测试剂和应用
|
|
CN113151471B
(zh)
*
|
2021-04-28 |
2022-08-12 |
复旦大学附属中山医院 |
用于检测肺腺癌kras突变的基因组合物、试剂盒和方法
|
|
WO2022245734A2
(en)
*
|
2021-05-17 |
2022-11-24 |
Corlieve Therapeutics |
Methods and compositions for treating epilepsy
|
|
CN113234834A
(zh)
*
|
2021-07-09 |
2021-08-10 |
北京泱深生物信息技术有限公司 |
一组用于胰腺癌预后的基因及其应用
|
|
CN113430273B
(zh)
*
|
2021-08-17 |
2022-05-27 |
广州齐凯生物科技有限公司 |
长链非编码rna linc01565在急性髓系白血病预后中的应用
|
|
CN113925975B
(zh)
*
|
2021-08-31 |
2024-05-28 |
杭州师范大学 |
p53及UTX信使RNA纳米粒的制备方法及该信使RNA的应用
|
|
CN118265544A
(zh)
|
2021-09-16 |
2024-06-28 |
艾维迪提生物科学公司 |
治疗面肩肱型肌营养不良的组合物和方法
|
|
CA3230433A1
(en)
*
|
2021-09-16 |
2023-03-23 |
Barbara MURPHY |
Methods for treating and diagnosing risk of renal allograft fibrosis and rejection
|
|
WO2023064604A1
(en)
*
|
2021-10-14 |
2023-04-20 |
New York Stem Cell Foundation, Inc. |
Modified cells and methods of use thereof
|
|
KR102711436B1
(ko)
*
|
2021-10-26 |
2024-09-26 |
사회복지법인 삼성생명공익재단 |
대장암의 치료 및 전이 억제용 조성물 및 이의 용도
|
|
EP4422752A1
(en)
*
|
2021-10-28 |
2024-09-04 |
Baylor College of Medicine |
Targeting neuronal sirpa for treatment and prevention of neurological disorders
|
|
WO2023081080A1
(en)
*
|
2021-11-05 |
2023-05-11 |
The Johns Hopkins University |
Use of biomarkers in diagnosing and treating lupus nephritis
|
|
CN114134147B
(zh)
*
|
2021-11-16 |
2023-11-14 |
山东大学 |
一种调控fzd9的非编码rna及其应用
|
|
CN114214322A
(zh)
*
|
2021-11-23 |
2022-03-22 |
中国辐射防护研究院 |
LincR-0003及其作为辐射损伤早期诊断的分子标志物的用途
|
|
WO2023111337A1
(en)
*
|
2021-12-17 |
2023-06-22 |
F. Hoffmann-La Roche Ag |
Antisense oligonucleotide
|
|
EP4453209A1
(en)
*
|
2021-12-20 |
2024-10-30 |
Freie Universität Berlin |
Methods and agents for increasing rbm3 expression
|
|
CN114196675A
(zh)
*
|
2021-12-24 |
2022-03-18 |
复旦大学附属肿瘤医院 |
靶向linc00624的反义寡核苷酸及其在乳腺癌治疗中的应用
|
|
CN114288315B
(zh)
*
|
2022-01-13 |
2022-08-16 |
暨南大学附属第一医院（广州华侨医院） |
一种包含ccp110抑制剂的药物组合物及其应用
|
|
CN115247176B
(zh)
*
|
2022-01-17 |
2023-06-20 |
郑州大学第一附属医院 |
一种长链非编码rna及其应用
|
|
CN114540500A
(zh)
*
|
2022-03-21 |
2022-05-27 |
深圳市陆为生物技术有限公司 |
评价乳腺癌患者整体生存的产品
|
|
KR20240165951A
(ko)
*
|
2022-03-23 |
2024-11-25 |
피와이씨 테라퓨틱스 리미티드 |
녹내장 치료 방법
|
|
CN114774445B
(zh)
*
|
2022-03-29 |
2024-01-02 |
中国人民解放军西部战区总医院 |
一种dynlt5基因在动脉粥样斑及组织修复中的应用
|
|
US20230313191A1
(en)
*
|
2022-03-29 |
2023-10-05 |
Direct Biologics Llc |
Rna comprising secretomes and methods of their use
|
|
WO2023191957A1
(en)
*
|
2022-03-30 |
2023-10-05 |
Mirimus, Inc. |
Compositions and methods of generating novel amirna
|
|
CN114574493A
(zh)
*
|
2022-04-02 |
2022-06-03 |
中国科学院遗传与发育生物学研究所 |
一种编辑绵羊SOCS2基因的sgRNA组合、扩增用引物和应用
|
|
US12071621B2
(en)
|
2022-04-05 |
2024-08-27 |
Avidity Biosciences, Inc. |
Anti-transferrin receptor antibody-PMO conjugates for inducing DMD exon 44 skipping
|
|
AU2023250231A1
(en)
*
|
2022-04-08 |
2024-10-31 |
Scineuro Therapeutics Inc. |
Oligonucleotide for reducing the expression of leucine-rich repeat kinase 2 (lrrk2) and its use for preventing and/or treating human diseases
|
|
WO2023201276A2
(en)
*
|
2022-04-12 |
2023-10-19 |
Orthobio Therapeutics, Inc. |
Lipid nanoparticles for gene editing systems
|
|
IT202200011546A1
(it)
*
|
2022-06-01 |
2022-09-01 |
Univ Degli Studi Di Trento |
Sequenze di RNA non codificanti in grado di aumentare l'espressione delle proteine CHD8 e CHD2
|
|
CN114959041B
(zh)
*
|
2022-06-19 |
2023-08-22 |
瓯江实验室 |
抑制结直肠癌增殖转移的新靶标与诊断标志物及其应用
|
|
CN119654412A
(zh)
*
|
2022-06-27 |
2025-03-18 |
中美瑞康核酸技术(南通)研究院有限公司 |
激活补体因子h表达的寡核苷酸调节剂
|
|
WO2024006994A2
(en)
*
|
2022-07-01 |
2024-01-04 |
The University Of Chicago |
Compositions and methods for the treatment of cancer by targeting the brca1 pseudogene 1 (brca1p1)
|
|
TW202403054A
(zh)
*
|
2022-07-04 |
2024-01-16 |
大陸商江蘇鵾遠生物科技股份有限公司 |
癌症特異性甲基化標誌物及其應用
|
|
CN115725587B
(zh)
*
|
2022-09-14 |
2023-07-18 |
中国人民解放军军事科学院军事医学研究院 |
一组特异性识别辐射敏感蛋白tp53i3的寡核苷酸适配体及试剂盒和检测方法
|
|
CN116103287B
(zh)
*
|
2022-09-19 |
2025-02-14 |
南通市肿瘤医院 |
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|
|
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(zh)
*
|
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|
|
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(en)
*
|
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|
|
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(en)
*
|
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|
|
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(en)
*
|
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|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(en)
*
|
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|
|
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(zh)
*
|
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|
|
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(ja)
*
|
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|
|
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(zh)
*
|
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|
|
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(en)
*
|
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|
|
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(en)
*
|
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|
|
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(en)
*
|
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|
|
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(zh)
*
|
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|
|
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(ja)
*
|
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|
|
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(ko)
*
|
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|
|
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(en)
*
|
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|
|
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(en)
*
|
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|
|
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(en)
*
|
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|
|
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(ko)
*
|
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|
|
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(en)
|
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|
|
WO2025171086A1
(en)
*
|
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|
|
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(en)
*
|
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|
|
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(en)
*
|
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|
|
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(en)
*
|
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|
|
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(en)
*
|
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|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(en)
*
|
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|
|
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(en)
*
|
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|
|
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(en)
*
|
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|
|
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(zh)
*
|
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|
|
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(en)
*
|
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|
|
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*
|
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|
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|
|
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*
|
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