JP2018501035A - 複数回使用使い捨てセットを有する多流体送達システムおよびその特徴 - Google Patents
複数回使用使い捨てセットを有する多流体送達システムおよびその特徴 Download PDFInfo
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Abstract
Description
本出願は、2015年10月15日に出願された「シリンジおよびマニホールドのための取り付け構成」と題する米国仮出願第62/242,090号、2015年10月15日に出願された「複数回使用使い捨てシステムのための回転可能弁」と題された米国仮出願第62/242,101号、2015年1月9日に出願された「多流体送達システムおよびそのための単回使用使い捨てセットのコネクタ」と題する米国仮出願第62/101,752号の優先権を主張するものであり、これらのそれぞれの開示の全体は、この参照により本明細書に組み込まれる。
(1)多患者用使い捨てセットの装填/非装填の確認
(2)多患者用使い捨てセットのロック/アンロック
(3)流体インジェクタシステム100の充填/パージ
(4)患者および/または注入処置に関連する情報および/またはデータの入力、ならびに
(5)注入処置の開始/停止
などであるが、これらに限定されないいくらかの個別の制御特徴を流体インジェクタシステム100の関連するオペレータに提供することが望ましい。流体インジェクタシステム100に関連するユーザインターフェース124および/または任意の電子処理ユニットは、病院ネットワークシステムなどの運用および/またはデータ記憶システムに有線または無線で接続されてもよい。
24、44 ルアーロックコネクタ
30 ねじ山
32 外側シュラウド
34、46、58、149 流体路
36 遠位ノズル
42 エンクロージャ
52 サムホイール
54 タブ
56、166、194 開口
60、80 管状導管
62 カニューレポート
64 液滴通路
66 吸収パッド
68 切り離しタブ
70 位置合わせ構造
71 位置合わせ溝
72 対応するスロット
74 管状シュラウド
76 フランジ
78 リッジ
82 共成形シール面
84 位置合わせ面
100 多流体医療用インジェクタ/注入システム、流体インジェクタシステム
102 インジェクタハウジング
103 ピストン要素
104 側面
106 上端
108 下端
110 ベース
112 車輪
114 ハンドル
116 ドア
118 バルク流体コネクタ
120 バルク流体源
122 支持部材
124 ユーザインターフェース
126 制御ボタン
128 アクセスポート
129 カニューレ
130 MUDS
132 シリンジ、ポンプ
133 保持構造
134 MUDS流体通路、MUDS流体ライン
135 外部クリップ
136 弁、弁アセンブリ
137 螺旋状に巻かれていない部分
138 シリンジ本体
139 シリンジ内部
140 シリンジの遠位端
142 シリンジの近位端
144 シリンジプランジャ
145 先端部または円錐部、円錐部分、円錐遠位端、遠位円錐端
146 排出出口、出口ポート、排出ポート、導管
147 充填ポート
148 マニホールド
148a マニホールド導管
148b 主流路
151 溝
152 流体出口ライン
153 ガスケット
154 フレーム
155 弁収容空洞
156 廃棄物リザーバ
158 収容空間
160 下部プレート
162 上部プレート
164 後部側壁
168 下部ガイド
170 シリンジスロット
172 ラッチ
174 カップリング機構
176 回転可能なカップリング
178 ブレード
180 スロット
181 リップ
182 外側側壁
183 縁部
184 傾斜面
186 上面
188 弾性部材
190 SUDS
192 接続ポート
196 廃棄物入口ポート
198 目視窓
200 表示
202 流体入口ポート
204 SUDS廃棄物出口ポート
206 スペーサ
207 フィン
208 チューブ
210 チューブの近位端
212 チューブの遠位端
214 コネクタ
216 ロッキングタブ
217 受入スロット
218 押圧面
220 第2の環状スカート
222 流体入口ポートの遠位端
224 第1の環状スカート
226 流体入口ポートの近位端
228、258 凹部
230 くぼみ
232、260 リブ
234 環状シール
236 一方向弁
238 センサシステム
240 センサフィン
242 センサ
250 弁体
252 弁棒
254 弁頭
256 長手方向軸線
262 外周
264 側壁
266、276 下端
268、275 内部
270 第1の側面開口
272 インサート、弁アセンブリ
274 外周側壁
278 第2の側面開口
900 電子制御装置
902 コンピューティングシステム環境
904 処理ユニット
906 システムバス
908 システムメモリ
910 非リムーバブルメモリのインターフェース
912 ハードディスクドライブ
914 リムーバブルな不揮発性メモリのインターフェース
916 磁気ディスクドライブユニット
918 リムーバブルな不揮発性の磁気ディスク
920 光ディスクドライブユニット
921 ユニバーサルシリアルバス(USB)ポート
922 リムーバブルな不揮発性の光ディスク
928 ユーザ入力インターフェース
930 モニタ
932 プリンタ
934 スピーカ
936 出力インターフェース
938 ネットワーク環境
940 通信装置
942 通信インターフェース
944 リモートコンピュータ
1346 遠位円錐端
1370、1470、1570、1670、1770、1870、1970、2070、2170、2270、2370、2470 マニホールド導管
1372、1472、1572、1672、1772、1872、1972、2072、2172、2272、2372、2472 導管シリンジ取り付け端
1375 相補的なねじ山
1380 ねじ付きスイベルナット
1382 雌ねじ
1385 半径方向内側フランジ
1390 周方向溝
1446、1546、1646、1746、1846、1946、2046、2146、2246、2346、2446 シリンジ流体ポート
1476、1576 オーバーモールドされたポリマーシース
1649 シリンジ流体ポートの内面
1673、1685 ロッキングフランジ
1690 マニホールドロッキング溝
1695 シリンジロッキング溝
1790 側方スロット
1875、1975、2085 半径方向フランジ
1890 可撓性クリップ
1990 Cクリップ
1995 長手方向スロット
1999 Oリング
2073 半径方向受入フランジ
2080 遠位周囲スロット
2086 レーザ溶接部
2175 末端部分
2185 周囲受入スロット
2186 エネルギーディレクタ
2380 管状空間
2480 レーザタック溶接部
L 長手方向軸線
P1、P2 揺動点
Claims (50)
- 複数回使用使い捨てセット(MUDS)であって、
複数のシリンジであって、該シリンジのそれぞれが、近位端および長手方向軸線に沿って前記近位端から離間される遠位端ならびにシリンジ内部を前記近位端と前記遠位端との間で往復移動可能なプランジャを有する複数のシリンジと、
前記複数のシリンジのそれぞれの前記遠位端と流体連通するマニホールドと、
前記複数のシリンジのうちの少なくとも1つの前記遠位端と流体連通する少なくとも1つの弁であって、前記マニホールドを介して前記複数のシリンジのうちの少なくとも1つの前記シリンジ内部に充填するための充填位置と、前記マニホールドを介して前記複数のシリンジのうちの少なくとも1つの前記シリンジ内部から流体を送達するための送達位置との間で動作可能な少なくとも1つの弁と、
前記少なくとも1つの弁が前記送達位置にあるときに前記マニホールドと流体連通する少なくとも1つの接続ポートと
を備える複数回使用使い捨てセット(MUDS)。 - 前記少なくとも1つの接続ポートが、前記複数のシリンジのうちの少なくとも1つに接続されるフレームに設けられている、請求項1に記載の複数回使用使い捨てセット(MUDS)。
- 前記少なくとも1つの接続ポートが、送達ラインを介して前記マニホールドと流体連通する、請求項1または2に記載の複数回使用使い捨てセット(MUDS)。
- 廃棄物リザーバと流体接続される廃棄物ポートをさらに備える、請求項1から3のいずれか一項に記載の複数回使用使い捨てセット(MUDS)。
- 前記複数のシリンジのそれぞれが、バルク流体源に接続されるように構成されたスパイクを有する充填ラインを備え、流体ラインのそれぞれが、前記少なくとも1つの弁が前記充填位置にあるときに前記マニホールドを介して前記シリンジ内部に充填するように構成される、請求項1から4のいずれか一項に記載の複数回使用使い捨てセット(MUDS)。
- 前記少なくとも1つの弁が、スロットであって、前記スロットを前記充填位置と前記送達位置との間で回転させるブレードと係合するスロットを備える、請求項1から5のいずれか一項に記載の複数回使用使い捨てセット(MUDS)。
- 多流体インジェクタシステムであって、
複数の往復動作可能なピストン要素を取り囲むハウジングを備える電動インジェクタと、
複数回使用使い捨てセット(MUDS)の複数のシリンジを取り外し可能に収容するように構成された収容空間であって、前記収容空間が、下部プレートおよび後部側壁によって前記下部プレートから離間される上部プレートを備え、前記MUDSの前記複数のシリンジが、前記上部プレートと前記下部プレートとの間で軸方向に支持されるようになっている収容空間と、
前記収容空間に関連する少なくとも1つのガイドと
を備え、
前記少なくとも1つのガイドが、前記収容空間内に前記MUDSを案内するために前記後部側壁に向かって挿入方向に狭まっている多流体インジェクタシステム。 - 前記MUDSと少なくとも1つのバルク流体源とを接続するように構成された複数のバルク流体コネクタをさらに備える、請求項7に記載の多流体インジェクタシステム。
- 前記上部プレートが、前記MUDSの前記複数のシリンジのうちの少なくとも1つを受け入れるように構成された複数のスロットを画成し、前記複数のスロットのそれぞれが、前記少なくとも1つのシリンジの円錐遠位端を受け入れるための嵌込凹部を画成し、前記円錐遠位端が、前記MUDSが前記収容空間に収容されたときに前記嵌込凹部に係合するようになっている、請求項7または8に記載の多流体インジェクタシステム。
- 前記上部プレートが、前記収容空間内に/から前記MUDSを挿入する/取り出すように構成された第1の位置と、前記収容空間内に前記MUDSをロックするように構成された第2の位置との間で移動可能である、請求項7から9のいずれか一項に記載の多流体インジェクタシステム。
- 前記上部プレートが、前記第2の位置に前記上部プレートをロックするためのラッチを備える、請求項10に記載の多流体インジェクタシステム。
- 前記MUDSの少なくとも1つの弁に係合するように構成された少なくとも1つのカップリングをさらに備える、請求項7から11のいずれか一項に記載の多流体インジェクタシステム。
- 前記少なくとも1つのカップリングが、前記MUDSの前記少なくとも1つの弁に形成されるスロットに自己位置合わせされるように構成されたブレードを有する回転可能なカップリングである、請求項12に記載の多流体インジェクタシステム。
- 複数回使用使い捨てセット(MUDS)であって、
近位端および長手方向軸線に沿って前記近位端から離間される遠位端ならびにシリンジ内部を前記近位端と前記遠位端との間で往復移動可能なプランジャを有する少なくとも1つのシリンジと、
前記少なくとも1つのシリンジの前記遠位端と流体連通するマニホールドと、
前記シリンジ内部と流体連通する少なくとも1つの弁であって、前記シリンジ内部に流体を充填するための充填位置と、前記シリンジ内部から前記流体を送達するための送達位置との間で動作可能な少なくとも1つの弁と、
前記少なくとも1つの弁が前記送達位置にあるときに前記マニホールドおよび前記シリンジ内部と流体連通する少なくとも1つの接続ポートと
を備える複数回使用使い捨てセット(MUDS)。 - 前記少なくとも1つの弁が、弁頭を有し、前記弁頭に、スロットが凹部として形成される、請求項14に記載の複数回使用使い捨てセット(MUDS)。
- 前記スロットが、前記充填位置と前記送達位置との間で前記少なくとも1つの弁を回転させるためのカップリング機構が前記少なくとも1つの弁の前記スロットに係合しているときに前記カップリング機構の少なくとも一部分を受け入れる形状に形成される、請求項15に記載の複数回使用使い捨てセット(MUDS)。
- 前記スロットが、前記弁の遠位端から前記弁の近位端への方向に狭まっている、請求項14または15に記載の複数回使用使い捨てセット(MUDS)。
- 前記少なくとも1つの弁が、前記充填位置と前記送達位置との間内で回転可能である、請求項14から17のいずれか一項に記載の複数回使用使い捨てセット(MUDS)。
- 前記充填位置では、前記少なくとも1つの弁が、バルク流体源と流体連通する充填ポートを介して前記シリンジ内部に充填し、前記マニホールドと流体連通する排出出口を介して前記シリンジ内部から流体を送達するように動作可能である、請求項14から18のいずれか一項に記載の複数回使用使い捨てセット(MUDS)。
- 前記少なくとも1つの接続ポートが、前記複数のシリンジのうちの少なくとも1つに接続されるフレームに設けられている、請求項14から19のいずれか一項に記載の複数回使用使い捨てセット(MUDS)。
- 前記少なくとも1つの接続ポートが、送達ラインを介して前記マニホールドと流体連通する、請求項14から20のいずれか一項に記載の複数回使用使い捨てセット(MUDS)。
- 前記少なくとも1つの接続ポートが、廃棄物リザーバと流体連通する廃棄物ポートを有する、請求項14〜21のいずれか一項に記載の複数回使用使い捨てセット(MUDS)。
- バルク流体源に接続されるスパイクを有する充填ラインをさらに備え、前記流体ラインが、前記少なくとも1つの弁が前記充填位置にあるとき、前記マニホールドを介して前記シリンジ内部に流体を充填する、請求項14から22のいずれか一項に記載の複数回使用使い捨てセット(MUDS)。
- 多流体インジェクタシステムであって、
少なくとも1つの往復動作可能なピストン要素を取り囲むハウジングを備える電動インジェクタと、
前記電動インジェクタに接続可能な複数回使用使い捨てセット(MUDS)であって、
近位端および長手方向軸線に沿って前記近位端から離間される遠位端ならびに前記少なくとも1つのピストン要素によってシリンジ内部を前記近位端と前記遠位端との間で往復移動可能なプランジャを有する少なくともの1つシリンジ、
前記少なくとも1つのシリンジの前記遠位端と流体連通するマニホールド、
前記シリンジ内部と流体連通する少なくとも1つの弁であって、前記シリンジ内部に流体を充填するための充填位置と、前記シリンジ内部から前記流体を送達するための送達位置との間で動作可能な少なくとも1つの弁、ならびに
前記少なくとも1つの弁が前記送達位置にあるときに前記マニホールドおよび前記シリンジ内部と流体連通する少なくとも1つの接続ポート
を備える複数回使用使い捨てセット(MUDS)と、
前記充填位置と前記送達位置との間で前記少なくとも1つの弁を動作させるためのカップリング機構と
を備える多流体インジェクタシステム。 - 前記カップリング機構が、ブレードを備え、前記少なくとも1つの弁が、前記カップリング機構の前記ブレードを受け入れる形状に形成されるスロットを有する、請求項24に記載の多流体インジェクタシステム。
- 前記カップリング機構の前記ブレードが前記少なくとも1つの弁の前記スロット内に受け入れられているとき、前記カップリング機構の回転により、前記少なくとも1つの弁が回転される、請求項25に記載の多流体インジェクタシステム。
- 前記カップリング機構が、前記少なくとも1つの弁の前記スロット内に前記カップリング機構の前記ブレードを受け入れるために、前記少なくとも1つの弁に自己位置合わせされる、請求項25または26に記載の多流体インジェクタシステム。
- 前記カップリング機構の前記ブレードが回転されて前記少なくとも1つの弁の前記スロットに位置合わせされるときに前記少なくとも1つの弁との接触を維持するために、前記カップリング機構に、ばね荷重がかけられる、請求項25から27のいずれか一項に記載の多流体インジェクタシステム。
- 前記カップリング機構の前記ブレードが前記少なくとも1つの弁の前記スロットに位置合わせされたとき、前記ブレードが、伸縮性のある弾性部材の復元作用下で前記スロット内に押し込まれる、請求項25から28のいずれか一項に記載の多流体インジェクタシステム。
- 前記カップリング機構を動作させるための駆動機構をさらに備える、請求項24から29のいずれか一項に記載の多流体インジェクタシステム。
- 前記駆動機構が、前記カップリング機構を回転させる、請求項24から30のいずれか一項に記載の多流体インジェクタシステム。
- 前記ブレードが、前記少なくとも1つの弁の長手方向軸線に対して傾斜した少なくとも1つの傾斜面を有する、請求項25から31のいずれか一項に記載の多流体インジェクタシステム。
- 複数回使用使い捨てセット(MUDS)であって、
複数のシリンジであって、該シリンジのそれぞれが、近位端および長手方向軸線に沿って前記近位端から離間される遠位端ならびにシリンジ内部を前記近位端と前記遠位端との間で往復移動可能なプランジャを有する複数のシリンジと、
前記複数のシリンジのそれぞれの前記遠位端に接続されるマニホールドと、
前記マニホールドに関連する少なくとも1つの弁であって、前記マニホールドを介して前記複数のシリンジのうちの少なくとも1つの前記シリンジ内部に充填するための充填位置と、前記マニホールドを介して前記複数のシリンジのうちの少なくとも1つの前記シリンジ内部から流体を送達するための送達位置との間で動作可能な少なくとも1つの弁と、
前記少なくとも1つの弁が前記充填位置にあるときに内部および前記複数のシリンジのうちの少なくとも1つの前記シリンジ内部と流体連通する少なくとも1つの充填ラインと、
前記少なくとも1つの弁が前記送達位置にあるときに前記マニホールドおよび前記複数のシリンジのうちの少なくとも1つの前記シリンジ内部と流体連通する少なくとも1つの接続ポートと
を備え、
前記少なくとも1つの弁が、弁頭を有し、前記弁頭に、スロットが凹部として形成され、
前記スロットが、前記充填位置と前記送達位置との間で前記少なくとも1つの弁を回転させるためのカップリング機構が前記少なくとも1つの弁の前記スロットに係合しているときに前記カップリング機構の少なくとも一部分を受け入れる形状に形成される複数回使用使い捨てセット(MUDS)。 - シリンジ/マニホールド構成であって、
シリンジ流体ポートを有する円錐遠位端を有する少なくとも1つのシリンジと、
少なくとも1つのマニホールド導管を備えるマニホールドであって、前記マニホールド導管が、主流路および導管シリンジ取り付け端に流体接続され、前記導管シリンジ取り付け端が、前記少なくとも1つのシリンジの前記シリンジ流体ポートと流体連通するマニホールドと
を備え、
前記少なくとも1つのマニホールド導管の前記導管シリンジ取り付け端が、前記少なくとも1つのシリンジの前記シリンジ流体ポートと流体密接続されるシリンジ/マニホールド構成。 - 前記少なくとも1つのマニホールド導管が、MUDS流体ラインと流体連通するように構成された充填ポートと、前記主流路と流体連通する排出出口と、弁収容空洞とを備え、前記排出出口および前記充填ポートが、弁収容空洞内の弁アセンブリを介して前記少なくとも1つのシリンジの内部と流体連通する、請求項34に記載のシリンジ/マニホールド構成。
- 前記弁アセンブリが、前記シリンジ内部に流体を充填するための充填位置と、前記シリンジ内部から前記流体を送達するための送達位置との間で動作可能である、請求項35に記載のシリンジ/マニホールド構成。
- 前記少なくとも1つのマニホールド導管の前記導管シリンジ取り付け端が、スイベルナット取り付け機構によって前記シリンジ流体ポートと流体密接続される、請求項34から36のいずれか一項に記載のシリンジ/マニホールド構成。
- 前記少なくとも1つのマニホールド導管の前記導管シリンジ取り付け端が、前記シリンジ流体ポートの内面との溶媒結合によって前記流体密接続を形成するオーバーモールドされたポリマーシースを備える、請求項34から36のいずれか一項に記載のシリンジ/マニホールド構成。
- 前記シリンジ流体ポートが、前記少なくとも1つのマニホールド導管の前記導管シリンジ取り付け端の内面との溶媒結合によって前記流体密接続を形成するオーバーモールドされたポリマーシースを備える、請求項34から36のいずれか一項に記載のシリンジ/マニホールド構成。
- 前記シリンジ流体ポートの内面および前記導管シリンジ取り付け端の内面がそれぞれ、半径方向内側に延在するロッキングフランジを備え、前記弁アセンブリが、前記シリンジ流体ポートおよび前記導管シリンジ取り付け端それぞれの前記ロッキングフランジとのロッキング係合を形成するように構成されたシリンジロッキング溝およびマニホールドロッキング溝を備える、請求項34から36のいずれか一項に記載のシリンジ/マニホールド構成。
- 前記導管シリンジ取り付け端の外周面が、UV活性化接着剤によって前記シリンジ流体ポートの内周面に接着され、前記シリンジ充填ポートが、硬化プロセス中の前記UV活性化接着剤の膨張を可能にする複数の側方スロットを備える、請求項34から36のいずれか一項に記載のシリンジ/マニホールド構成。
- 前記シリンジ流体ポートの外周面が、UV活性化接着剤によって前記導管シリンジ取り付け端の内周面に接着され、前記導管シリンジ取り付け端が、硬化プロセス中の前記UV活性化接着剤の膨張を可能にする複数の側方スロットを備える、請求項34から36のいずれか一項に記載のシリンジ/マニホールド構成。
- 前記シリンジの前記円錐遠位端が、前記導管シリンジ取り付け端の外周上の半径方向フランジに係合するように構成された、遠位方向を向いた複数の可撓性クリップを備える、請求項34から36のいずれか一項に記載のシリンジ/マニホールド構成。
- 前記シリンジ流体ポートが、長手方向スロットを含み、前記導管シリンジ取り付け端が、半径方向フランジを備え、前記導管シリンジ取り付け端が、前記半径方向フランジが前記長手方向スロットに対して近位方向に隣接する位置まで前記シリンジ流体ポートに挿入され、前記導管シリンジ取り付け端と前記シリンジ流体ポートとの接続が、前記長手方向スロットに挿入されるCクリップによって維持される、請求項34から36のいずれか一項に記載のシリンジ/マニホールド構成。
- 前記シリンジ流体ポートおよび前記導管シリンジ取り付け端の一方が、半径方向フランジを備え、前記シリンジ流体ポートおよび前記導管シリンジ取り付け端の他方が、前記半径方向フランジを受け入れる相補的な半径方向受入フランジを備え、前記半径方向フランジおよび前記相補的な半径方向受入フランジが、レーザ溶接部によって互いに接続される、請求項34から36のいずれか一項に記載のシリンジ/マニホールド構成。
- 前記シリンジ流体ポートおよび前記導管シリンジ取り付け端の一方が、エネルギーディレクタを含む周囲受入スロットを備え、前記シリンジ流体ポートおよび前記導管シリンジ取り付け端の他方が、前記周囲受入スロット内に係合して受け入れられる末端部分を備え、前記末端部分と前記周囲受入スロットとが、超音波溶接によって互いに接続される、請求項34から36のいずれか一項に記載のシリンジ/マニホールド構成。
- 前記シリンジ流体ポートが、前記導管シリンジ取り付け端の雄ルアーコネクタと流体密接続を形成する雌ルアーコネクタを備え、前記シリンジ流体ポートが、UV活性化接着剤を受け入れるように構成された、前記シリンジ流体ポートと前記導管シリンジ取り付け端との間の遠位周囲スロットをさらに備える、請求項34から36のいずれか一項に記載のシリンジ/マニホールド構成。
- 前記シリンジ流体ポートと前記導管シリンジ取り付け端との係合により、前記シリンジ流体ポートの内面と前記導管シリンジ取り付け端の外面との間に管状空間が画成され、前記管状空間が、UV活性化接着剤を受け入れるように構成される、請求項34から36のいずれか一項に記載のシリンジ/マニホールド構成。
- 前記シリンジ流体ポートと前記導管シリンジ取り付け端との係合により、前記導管シリンジ取り付け端の内面と前記シリンジ流体ポートの外面との間に管状空間が画成され、前記管状空間が、UV活性化接着剤を受け入れるように構成される、請求項34から36のいずれか一項に記載のシリンジ/マニホールド構成。
- 前記シリンジ流体ポートが、前記導管シリンジ取り付け端の雄ルアーコネクタと流体密接続を形成する雌ルアーコネクタを備え、前記シリンジ流体ポートが、レーザタック溶接部によって前記導管シリンジ取り付け端に溶接される、請求項34から36のいずれか一項に記載のシリンジ/マニホールド構成。
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JP (3) | JP6749918B2 (ja) |
KR (3) | KR102528289B1 (ja) |
CN (2) | CN113069635B (ja) |
AU (3) | AU2016205275B2 (ja) |
CA (2) | CA3207200A1 (ja) |
HK (1) | HK1246634A1 (ja) |
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