JP2018500006A - 改変t細胞における遺伝子発現の改変およびその使用 - Google Patents

改変t細胞における遺伝子発現の改変およびその使用 Download PDF

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JP2018500006A
JP2018500006A JP2017523296A JP2017523296A JP2018500006A JP 2018500006 A JP2018500006 A JP 2018500006A JP 2017523296 A JP2017523296 A JP 2017523296A JP 2017523296 A JP2017523296 A JP 2017523296A JP 2018500006 A JP2018500006 A JP 2018500006A
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cells
cell
tcr
modified
antigen
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JP2018500006A5 (enExample
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ヤンビン チャオ
ヤンビン チャオ
チアンタオ レン
チアンタオ レン
シャオジュン リュー
シャオジュン リュー
カール エイチ. ジューン
カール エイチ. ジューン
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ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア
ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア
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JP2017523296A 2014-10-31 2015-10-15 改変t細胞における遺伝子発現の改変およびその使用 Ceased JP2018500006A (ja)

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US201462073651P 2014-10-31 2014-10-31
US62/073,651 2014-10-31
PCT/US2015/055780 WO2016069282A1 (en) 2014-10-31 2015-10-15 Altering gene expression in modified t cells and uses thereof

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JP2017523279A Active JP6879910B2 (ja) 2014-10-31 2015-10-15 Cart細胞における遺伝子発現の改変およびその使用
JP2020208069A Active JP7792114B2 (ja) 2014-10-31 2020-12-16 Cart細胞における遺伝子発現の改変およびその使用
JP2023004286A Active JP7657474B2 (ja) 2014-10-31 2023-01-16 Cart細胞における遺伝子発現の改変およびその使用
JP2025043131A Pending JP2025089344A (ja) 2014-10-31 2025-03-18 Cart細胞における遺伝子発現の改変およびその使用

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JP2020208069A Active JP7792114B2 (ja) 2014-10-31 2020-12-16 Cart細胞における遺伝子発現の改変およびその使用
JP2023004286A Active JP7657474B2 (ja) 2014-10-31 2023-01-16 Cart細胞における遺伝子発現の改変およびその使用
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US (7) US20170335331A1 (enExample)
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AU (4) AU2015339743C1 (enExample)
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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018510657A (ja) * 2015-03-27 2018-04-19 プレジデント アンド フェローズ オブ ハーバード カレッジ 改変t細胞ならびにそれを作製および使用する方法
KR20210019993A (ko) * 2018-04-05 2021-02-23 주노 쎄러퓨티크스 인코퍼레이티드 Τ 세포 수용체 및 이를 발현하는 조작된 세포
JP2022512703A (ja) * 2018-10-16 2022-02-07 インテリア セラピューティクス,インコーポレイテッド 免疫療法のための組成物および方法
JP2022518463A (ja) * 2019-01-16 2022-03-15 ビーム セラピューティクス インク. 抗新生物活性および免疫抑制抵抗性の増強を有する改変された免疫細胞

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EP2734621B1 (en) 2011-07-22 2019-09-04 President and Fellows of Harvard College Evaluation and improvement of nuclease cleavage specificity
KR102073901B1 (ko) 2011-09-08 2020-02-05 예다 리서치 앤드 디벨럽먼트 캄파니 리미티드 항 제3자 중심 기억 t 세포, 이의 제조 방법, 및 이식 및 질환 치료에서의 이의 용도
US20150044192A1 (en) 2013-08-09 2015-02-12 President And Fellows Of Harvard College Methods for identifying a target site of a cas9 nuclease
US9359599B2 (en) 2013-08-22 2016-06-07 President And Fellows Of Harvard College Engineered transcription activator-like effector (TALE) domains and uses thereof
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