JP2018500006A - 改変t細胞における遺伝子発現の改変およびその使用 - Google Patents
改変t細胞における遺伝子発現の改変およびその使用 Download PDFInfo
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- JP2018500006A JP2018500006A JP2017523296A JP2017523296A JP2018500006A JP 2018500006 A JP2018500006 A JP 2018500006A JP 2017523296 A JP2017523296 A JP 2017523296A JP 2017523296 A JP2017523296 A JP 2017523296A JP 2018500006 A JP2018500006 A JP 2018500006A
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- C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462073651P | 2014-10-31 | 2014-10-31 | |
| US62/073,651 | 2014-10-31 | ||
| PCT/US2015/055780 WO2016069282A1 (en) | 2014-10-31 | 2015-10-15 | Altering gene expression in modified t cells and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018500006A true JP2018500006A (ja) | 2018-01-11 |
| JP2018500006A5 JP2018500006A5 (enExample) | 2018-11-22 |
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Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017523296A Ceased JP2018500006A (ja) | 2014-10-31 | 2015-10-15 | 改変t細胞における遺伝子発現の改変およびその使用 |
| JP2017523279A Active JP6879910B2 (ja) | 2014-10-31 | 2015-10-15 | Cart細胞における遺伝子発現の改変およびその使用 |
| JP2020208069A Active JP7792114B2 (ja) | 2014-10-31 | 2020-12-16 | Cart細胞における遺伝子発現の改変およびその使用 |
| JP2023004286A Active JP7657474B2 (ja) | 2014-10-31 | 2023-01-16 | Cart細胞における遺伝子発現の改変およびその使用 |
| JP2025043131A Pending JP2025089344A (ja) | 2014-10-31 | 2025-03-18 | Cart細胞における遺伝子発現の改変およびその使用 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017523279A Active JP6879910B2 (ja) | 2014-10-31 | 2015-10-15 | Cart細胞における遺伝子発現の改変およびその使用 |
| JP2020208069A Active JP7792114B2 (ja) | 2014-10-31 | 2020-12-16 | Cart細胞における遺伝子発現の改変およびその使用 |
| JP2023004286A Active JP7657474B2 (ja) | 2014-10-31 | 2023-01-16 | Cart細胞における遺伝子発現の改変およびその使用 |
| JP2025043131A Pending JP2025089344A (ja) | 2014-10-31 | 2025-03-18 | Cart細胞における遺伝子発現の改変およびその使用 |
Country Status (13)
| Country | Link |
|---|---|
| US (7) | US20170335331A1 (enExample) |
| EP (4) | EP3215168B1 (enExample) |
| JP (5) | JP2018500006A (enExample) |
| KR (5) | KR102546296B1 (enExample) |
| CN (3) | CN107206024B (enExample) |
| AU (4) | AU2015339743C1 (enExample) |
| BR (1) | BR112017008693A2 (enExample) |
| CA (2) | CA2964948A1 (enExample) |
| EA (1) | EA201790953A1 (enExample) |
| ES (1) | ES2983094T3 (enExample) |
| MX (2) | MX2017005698A (enExample) |
| PL (1) | PL3215166T3 (enExample) |
| WO (2) | WO2016069282A1 (enExample) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2018510657A (ja) * | 2015-03-27 | 2018-04-19 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 改変t細胞ならびにそれを作製および使用する方法 |
| KR20210019993A (ko) * | 2018-04-05 | 2021-02-23 | 주노 쎄러퓨티크스 인코퍼레이티드 | Τ 세포 수용체 및 이를 발현하는 조작된 세포 |
| JP2022512703A (ja) * | 2018-10-16 | 2022-02-07 | インテリア セラピューティクス,インコーポレイテッド | 免疫療法のための組成物および方法 |
| JP2022518463A (ja) * | 2019-01-16 | 2022-03-15 | ビーム セラピューティクス インク. | 抗新生物活性および免疫抑制抵抗性の増強を有する改変された免疫細胞 |
Families Citing this family (205)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2734621B1 (en) | 2011-07-22 | 2019-09-04 | President and Fellows of Harvard College | Evaluation and improvement of nuclease cleavage specificity |
| KR102073901B1 (ko) | 2011-09-08 | 2020-02-05 | 예다 리서치 앤드 디벨럽먼트 캄파니 리미티드 | 항 제3자 중심 기억 t 세포, 이의 제조 방법, 및 이식 및 질환 치료에서의 이의 용도 |
| US20150044192A1 (en) | 2013-08-09 | 2015-02-12 | President And Fellows Of Harvard College | Methods for identifying a target site of a cas9 nuclease |
| US9359599B2 (en) | 2013-08-22 | 2016-06-07 | President And Fellows Of Harvard College | Engineered transcription activator-like effector (TALE) domains and uses thereof |
| US9526784B2 (en) | 2013-09-06 | 2016-12-27 | President And Fellows Of Harvard College | Delivery system for functional nucleases |
| US9388430B2 (en) | 2013-09-06 | 2016-07-12 | President And Fellows Of Harvard College | Cas9-recombinase fusion proteins and uses thereof |
| US9340799B2 (en) | 2013-09-06 | 2016-05-17 | President And Fellows Of Harvard College | MRNA-sensing switchable gRNAs |
| US11053481B2 (en) | 2013-12-12 | 2021-07-06 | President And Fellows Of Harvard College | Fusions of Cas9 domains and nucleic acid-editing domains |
| CN111471674A (zh) | 2014-03-05 | 2020-07-31 | 国立大学法人神户大学 | 特异性转变靶向dna序列的核酸碱基的基因组序列的修饰方法、及其使用的分子复合体 |
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| JP2018510657A (ja) * | 2015-03-27 | 2018-04-19 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 改変t細胞ならびにそれを作製および使用する方法 |
| KR20210019993A (ko) * | 2018-04-05 | 2021-02-23 | 주노 쎄러퓨티크스 인코퍼레이티드 | Τ 세포 수용체 및 이를 발현하는 조작된 세포 |
| JP2021520198A (ja) * | 2018-04-05 | 2021-08-19 | ジュノー セラピューティクス インコーポレイテッド | T細胞受容体およびそれを発現する操作された細胞 |
| JP7410868B2 (ja) | 2018-04-05 | 2024-01-10 | ジュノー セラピューティクス インコーポレイテッド | T細胞受容体およびそれを発現する操作された細胞 |
| KR102764123B1 (ko) | 2018-04-05 | 2025-02-05 | 주노 쎄러퓨티크스 인코퍼레이티드 | Τ 세포 수용체 및 이를 발현하는 조작된 세포 |
| JP2022512703A (ja) * | 2018-10-16 | 2022-02-07 | インテリア セラピューティクス,インコーポレイテッド | 免疫療法のための組成物および方法 |
| JP2022518463A (ja) * | 2019-01-16 | 2022-03-15 | ビーム セラピューティクス インク. | 抗新生物活性および免疫抑制抵抗性の増強を有する改変された免疫細胞 |
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