JP2018500006A - 改変t細胞における遺伝子発現の改変およびその使用 - Google Patents

改変t細胞における遺伝子発現の改変およびその使用 Download PDF

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JP2018500006A
JP2018500006A JP2017523296A JP2017523296A JP2018500006A JP 2018500006 A JP2018500006 A JP 2018500006A JP 2017523296 A JP2017523296 A JP 2017523296A JP 2017523296 A JP2017523296 A JP 2017523296A JP 2018500006 A JP2018500006 A JP 2018500006A
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cells
cell
tcr
modified
antigen
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JP2018500006A5 (enExample
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ヤンビン チャオ
ヤンビン チャオ
チアンタオ レン
チアンタオ レン
シャオジュン リュー
シャオジュン リュー
カール エイチ. ジューン
カール エイチ. ジューン
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ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア
ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア
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Application filed by ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア, ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア filed Critical ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア
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JP2017523296A 2014-10-31 2015-10-15 改変t細胞における遺伝子発現の改変およびその使用 Ceased JP2018500006A (ja)

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Application Number Priority Date Filing Date Title
US201462073651P 2014-10-31 2014-10-31
US62/073,651 2014-10-31
PCT/US2015/055780 WO2016069282A1 (en) 2014-10-31 2015-10-15 Altering gene expression in modified t cells and uses thereof

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JP2018500006A true JP2018500006A (ja) 2018-01-11
JP2018500006A5 JP2018500006A5 (enExample) 2018-11-22

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JP2017523296A Ceased JP2018500006A (ja) 2014-10-31 2015-10-15 改変t細胞における遺伝子発現の改変およびその使用
JP2017523279A Active JP6879910B2 (ja) 2014-10-31 2015-10-15 Cart細胞における遺伝子発現の改変およびその使用
JP2020208069A Active JP7792114B2 (ja) 2014-10-31 2020-12-16 Cart細胞における遺伝子発現の改変およびその使用
JP2023004286A Active JP7657474B2 (ja) 2014-10-31 2023-01-16 Cart細胞における遺伝子発現の改変およびその使用
JP2025043131A Pending JP2025089344A (ja) 2014-10-31 2025-03-18 Cart細胞における遺伝子発現の改変およびその使用

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JP2020208069A Active JP7792114B2 (ja) 2014-10-31 2020-12-16 Cart細胞における遺伝子発現の改変およびその使用
JP2023004286A Active JP7657474B2 (ja) 2014-10-31 2023-01-16 Cart細胞における遺伝子発現の改変およびその使用
JP2025043131A Pending JP2025089344A (ja) 2014-10-31 2025-03-18 Cart細胞における遺伝子発現の改変およびその使用

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US (8) US20170335331A1 (enExample)
EP (4) EP4219725A3 (enExample)
JP (5) JP2018500006A (enExample)
KR (5) KR102546296B1 (enExample)
CN (3) CN114836385B (enExample)
AU (4) AU2015339744B2 (enExample)
BR (1) BR112017008693A2 (enExample)
CA (2) CA2964953A1 (enExample)
EA (1) EA201790953A1 (enExample)
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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018510657A (ja) * 2015-03-27 2018-04-19 プレジデント アンド フェローズ オブ ハーバード カレッジ 改変t細胞ならびにそれを作製および使用する方法
KR20210019993A (ko) * 2018-04-05 2021-02-23 주노 쎄러퓨티크스 인코퍼레이티드 Τ 세포 수용체 및 이를 발현하는 조작된 세포
JP2022512703A (ja) * 2018-10-16 2022-02-07 インテリア セラピューティクス,インコーポレイテッド 免疫療法のための組成物および方法
JP2022518463A (ja) * 2019-01-16 2022-03-15 ビーム セラピューティクス インク. 抗新生物活性および免疫抑制抵抗性の増強を有する改変された免疫細胞
US12576151B2 (en) 2020-09-25 2026-03-17 Beam Therapeutics Inc. Fratricide resistant modified immune cells and methods of using the same
US12594301B2 (en) 2019-09-27 2026-04-07 Beam Therapeutics Inc. Compositions and methods for treatment of liquid cancers
US12600971B2 (en) 2019-02-13 2026-04-14 Beam Therapeutics Inc. Modified immune cells having adenosine deaminase base editors for modifying a nucleobase in a target sequence

Families Citing this family (208)

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US12600971B2 (en) 2019-02-13 2026-04-14 Beam Therapeutics Inc. Modified immune cells having adenosine deaminase base editors for modifying a nucleobase in a target sequence
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