JP2017502310A5 - - Google Patents
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- JP2017502310A5 JP2017502310A5 JP2016554540A JP2016554540A JP2017502310A5 JP 2017502310 A5 JP2017502310 A5 JP 2017502310A5 JP 2016554540 A JP2016554540 A JP 2016554540A JP 2016554540 A JP2016554540 A JP 2016554540A JP 2017502310 A5 JP2017502310 A5 JP 2017502310A5
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- 230000005284 excitation Effects 0.000 claims 33
- 230000008878 coupling Effects 0.000 claims 17
- 238000010168 coupling process Methods 0.000 claims 17
- 238000005859 coupling reaction Methods 0.000 claims 17
- 238000000034 method Methods 0.000 claims 12
- 239000003550 marker Substances 0.000 claims 9
- 230000005855 radiation Effects 0.000 claims 8
- 238000009826 distribution Methods 0.000 claims 7
- 230000001678 irradiating effect Effects 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 238000000151 deposition Methods 0.000 claims 1
- 238000002372 labelling Methods 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 238000012284 sample analysis method Methods 0.000 claims 1
- 230000003595 spectral effect Effects 0.000 claims 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361905282P | 2013-11-17 | 2013-11-17 | |
| US61/905,282 | 2013-11-17 | ||
| US201361917926P | 2013-12-18 | 2013-12-18 | |
| US61/917,926 | 2013-12-18 | ||
| US201461941916P | 2014-02-19 | 2014-02-19 | |
| US61/941,916 | 2014-02-19 | ||
| PCT/US2014/066013 WO2015074004A1 (en) | 2013-11-17 | 2014-11-17 | Integrated device with external light source for probing detecting and analyzing molecules |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017502310A JP2017502310A (ja) | 2017-01-19 |
| JP2017502310A5 true JP2017502310A5 (enExample) | 2017-12-28 |
| JP6573899B2 JP6573899B2 (ja) | 2019-09-11 |
Family
ID=52014380
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016554539A Expired - Fee Related JP6673843B2 (ja) | 2013-11-17 | 2014-11-17 | 分子をプローブし、検出し、分析するための光学システム及びアッセイ・チップ |
| JP2016554541A Pending JP2016537999A (ja) | 2013-11-17 | 2014-11-17 | 生物学的な試料及び化学的な試料の迅速な分析のためのアクティブ・ソース・ピクセル集積デバイス |
| JP2016554540A Active JP6573899B2 (ja) | 2013-11-17 | 2014-11-17 | 分子をプローブし、検出し、及び分析するための、外部光源を備えた集積デバイス |
| JP2020037466A Expired - Fee Related JP7015336B2 (ja) | 2013-11-17 | 2020-03-05 | 分子をプローブし、検出し、分析するための光学システム及びアッセイ・チップ |
| JP2021018615A Active JP7242727B2 (ja) | 2013-11-17 | 2021-02-08 | 生物学的な試料及び化学的な試料の迅速な分析のためのアクティブ・ソース・ピクセル集積デバイス |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016554539A Expired - Fee Related JP6673843B2 (ja) | 2013-11-17 | 2014-11-17 | 分子をプローブし、検出し、分析するための光学システム及びアッセイ・チップ |
| JP2016554541A Pending JP2016537999A (ja) | 2013-11-17 | 2014-11-17 | 生物学的な試料及び化学的な試料の迅速な分析のためのアクティブ・ソース・ピクセル集積デバイス |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020037466A Expired - Fee Related JP7015336B2 (ja) | 2013-11-17 | 2020-03-05 | 分子をプローブし、検出し、分析するための光学システム及びアッセイ・チップ |
| JP2021018615A Active JP7242727B2 (ja) | 2013-11-17 | 2021-02-08 | 生物学的な試料及び化学的な試料の迅速な分析のためのアクティブ・ソース・ピクセル集積デバイス |
Country Status (10)
| Country | Link |
|---|---|
| US (12) | US9983135B2 (enExample) |
| EP (6) | EP3068901B1 (enExample) |
| JP (5) | JP6673843B2 (enExample) |
| KR (4) | KR102240166B1 (enExample) |
| CN (5) | CN105980580B (enExample) |
| AU (4) | AU2014348302B2 (enExample) |
| BR (3) | BR112016011061B1 (enExample) |
| CA (3) | CA2930836A1 (enExample) |
| MX (4) | MX381541B (enExample) |
| WO (3) | WO2015074005A1 (enExample) |
Families Citing this family (197)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9593371B2 (en) | 2013-12-27 | 2017-03-14 | Intel Corporation | Integrated photonic electronic sensor arrays for nucleic acid sequencing |
| KR102240166B1 (ko) | 2013-11-17 | 2021-04-14 | 퀀텀-에스아이 인코포레이티드 | 분자들을 프로빙 검출 및 분석하기 위한 외부 광원을 구비한 통합 디바이스 |
| US11287484B2 (en) | 2014-02-03 | 2022-03-29 | Innovaura Corporation | Method and apparatus for triage of electronic items using magnetic field detection |
| WO2015117157A1 (en) * | 2014-02-03 | 2015-08-06 | Electromagnetic Landmarks Inc. | Magnetic sensor array and system |
| US11747407B2 (en) | 2014-02-03 | 2023-09-05 | Innovaura Corporation | System and method for characterizing defects in electronic items using magnetic field detection |
| EP3194934B1 (en) | 2014-08-08 | 2024-03-06 | Quantum-Si Incorporated | Integrated device for use with an external light source for probing, detecting, and analyzing molecules by luminescence lifetime measurements |
| US10174363B2 (en) | 2015-05-20 | 2019-01-08 | Quantum-Si Incorporated | Methods for nucleic acid sequencing |
| CN107112333B (zh) | 2014-08-08 | 2020-07-10 | 宽腾矽公司 | 基于入射光子到达时间的识别、成像、测序法及存储介质 |
| CA2957543A1 (en) | 2014-08-08 | 2016-02-11 | Quantum-Si Incorporated | Optical system and assay chip for probing, detecting and analyzing molecules |
| US9721751B2 (en) * | 2014-08-22 | 2017-08-01 | The Board Of Trustees Of The Leland Stanford Junior University | Electron microscopy specimen and method of fabrication |
| US10352899B2 (en) | 2014-10-06 | 2019-07-16 | ALVEO Technologies Inc. | System and method for detection of silver |
| US10196678B2 (en) | 2014-10-06 | 2019-02-05 | ALVEO Technologies Inc. | System and method for detection of nucleic acids |
| US9506908B2 (en) | 2014-10-06 | 2016-11-29 | Alveo Technologies, Inc. | System for detection of analytes |
| US10627358B2 (en) | 2014-10-06 | 2020-04-21 | Alveo Technologies, Inc. | Method for detection of analytes |
| US9921182B2 (en) | 2014-10-06 | 2018-03-20 | ALVEO Technologies Inc. | System and method for detection of mercury |
| US10184892B2 (en) * | 2014-10-29 | 2019-01-22 | Horiba Instruments Incorporated | Determination of water treatment parameters based on absorbance and fluorescence |
| TR201910871T4 (tr) | 2015-01-20 | 2019-08-21 | Hyris Ltd | Sıvı bir numunede floresans ölçümü için dedektör. |
| US10018608B2 (en) * | 2015-02-27 | 2018-07-10 | Vitaly Talyansky | System to authenticate and identify items |
| CN107615121B (zh) | 2015-03-16 | 2021-04-16 | 加利福尼亚太平洋生物科学股份有限公司 | 用于自由空间光耦合的集成装置及系统 |
| US10605730B2 (en) | 2015-05-20 | 2020-03-31 | Quantum-Si Incorporated | Optical sources for fluorescent lifetime analysis |
| US11466316B2 (en) | 2015-05-20 | 2022-10-11 | Quantum-Si Incorporated | Pulsed laser and bioanalytic system |
| US9874693B2 (en) | 2015-06-10 | 2018-01-23 | The Research Foundation For The State University Of New York | Method and structure for integrating photonics with CMOs |
| CA2989344C (en) | 2015-06-12 | 2023-09-26 | Pacific Biosciences Of California, Inc. | Integrated target waveguide devices and systems for optical coupling |
| TWI697674B (zh) * | 2015-07-27 | 2020-07-01 | 體學生物科技股份有限公司 | 感測模組及感測方法 |
| WO2017019768A1 (en) * | 2015-07-30 | 2017-02-02 | The Regents Of The University Of California | Optical cavity pcr |
| TW201723482A (zh) * | 2015-08-18 | 2017-07-01 | 新加坡科技研究局 | 光學結構及光學光偵測系統 |
| US9733188B2 (en) * | 2015-09-21 | 2017-08-15 | International Business Machines Corporation | Enhancing on-chip fluorescence detection |
| CA3002955A1 (en) | 2015-10-22 | 2017-04-27 | Jacob Schneiderman | Systems and methods for identifying and treating biological materials |
| KR101720434B1 (ko) * | 2015-11-10 | 2017-03-28 | 한국과학기술원 | 광 위상배열 안테나 |
| US10248838B2 (en) * | 2015-12-04 | 2019-04-02 | The Regents Of The University Of California | Method and device for single molecule imaging |
| WO2017151207A2 (en) * | 2015-12-14 | 2017-09-08 | Massachusetts Institute Of Technology | Apparatus and methods for spectroscopy and broadband light emission using two-dimensional plasmon fields |
| WO2017123658A1 (en) | 2016-01-12 | 2017-07-20 | Sxaymiq Technologies Llc | Light emitting diode display |
| KR102763291B1 (ko) | 2016-01-28 | 2025-02-04 | 로스웰 엠이 아이엔씨. | 대량 병렬 ｄｎａ 시퀀싱 장치 |
| US11624725B2 (en) | 2016-01-28 | 2023-04-11 | Roswell Blotechnologies, Inc. | Methods and apparatus for measuring analytes using polymerase in large scale molecular electronics sensor arrays |
| CA3053103A1 (en) | 2016-02-09 | 2017-08-17 | Roswell Biotechnologies, Inc. | Electronic label-free dna and genome sequencing |
| JP2019512090A (ja) | 2016-02-17 | 2019-05-09 | テッセラクト ヘルス インコーポレイテッドＴｅｓｓｅｒａｃｔ Ｈｅａｌｔｈ，Ｉｎｃ． | 寿命イメージングおよび検出用途のためのセンサおよびデバイス |
| US10597767B2 (en) | 2016-02-22 | 2020-03-24 | Roswell Biotechnologies, Inc. | Nanoparticle fabrication |
| CA3018582A1 (en) * | 2016-03-25 | 2017-09-28 | Bioceryx Inc. | Apparatuses and methods for assessing target sequence numbers |
| CN113916788B (zh) * | 2016-04-22 | 2024-12-10 | 伊鲁米那股份有限公司 | 在发光成像中使用的设备和组成物及使用其的方法 |
| US10451518B2 (en) * | 2016-05-10 | 2019-10-22 | Rd2, Llc | All fiber temperature and air density sensor |
| WO2017205868A1 (en) * | 2016-05-27 | 2017-11-30 | Singulex, Inc. | Camera-based single molecule reader |
| US11529213B2 (en) | 2016-05-30 | 2022-12-20 | David Akselrod | Backscatter device-based dental imaging apparatus |
| US11389277B2 (en) | 2016-07-18 | 2022-07-19 | David Akselrod | Material property monitoring using backscatter devices |
| EP4009330A1 (en) | 2016-06-01 | 2022-06-08 | Quantum-si Incorporated | Pulse caller and base caller |
| CN114674788A (zh) * | 2016-06-01 | 2022-06-28 | 宽腾矽公司 | 用于检测及分析分子的集成装置 |
| US10758153B2 (en) * | 2016-07-18 | 2020-09-01 | David Akselrod | Material property monitoring and detection using wireless devices |
| US9829456B1 (en) | 2016-07-26 | 2017-11-28 | Roswell Biotechnologies, Inc. | Method of making a multi-electrode structure usable in molecular sensing devices |
| EP3491380B1 (en) | 2016-08-01 | 2021-06-16 | Genprime, Inc. | System and method to interpret tests that change color to indicate the presence or non-presence of a compound |
| US10656088B2 (en) * | 2016-08-12 | 2020-05-19 | Silanna UV Technologies Pte Ltd | Ultraviolet biosensor |
| EP3285052A1 (en) | 2016-08-19 | 2018-02-21 | IMEC vzw | Photonic circuit with integrated light coupler |
| KR20220151011A (ko) | 2016-09-23 | 2022-11-11 | 알베오 테크놀로지스 인크. | 분석물을 검출하기 위한 방법 및 조성물 |
| TWI777989B (zh) | 2016-11-03 | 2022-09-21 | 大陸商深圳華大智造科技有限公司 | 用於生物或化學分析的生物感測器以及製造其的方法 |
| FR3058521B1 (fr) * | 2016-11-08 | 2021-01-08 | Univ Montpellier | Dispositif et procede de detection de presence de molecules determinees, biocapteur |
| JP6770197B2 (ja) * | 2016-12-15 | 2020-10-14 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | 適応ナノ細孔信号圧縮 |
| BR112019012069A2 (pt) | 2016-12-16 | 2019-11-12 | Quantum-Si Incorporated | conjunto de modelagem e direcionamento de feixe compacto |
| JP2018100959A (ja) * | 2016-12-16 | 2018-06-28 | シャープ株式会社 | 検出器、ならびに、検出器の校正方法、補正方法、検出装置 |
| CN110088993B (zh) * | 2016-12-16 | 2022-02-08 | 宽腾矽公司 | 紧密的锁模雷射模块 |
| TW201837184A (zh) | 2016-12-19 | 2018-10-16 | 美商寬騰矽公司 | 分子載入樣品孔以供分析 |
| US10845308B2 (en) | 2016-12-22 | 2020-11-24 | Quantum-Si Incorporated | Integrated photodetector with direct binning pixel |
| CA3052062A1 (en) | 2017-01-10 | 2018-07-19 | Roswell Biotechnologies, Inc. | Methods and systems for dna data storage |
| KR102601324B1 (ko) | 2017-01-19 | 2023-11-10 | 로스웰 바이오테크놀로지스 인코포레이티드 | 2차원 레이어 재료를 포함하는 솔리드 스테이트 시퀀싱 디바이스들 |
| US11419703B2 (en) | 2017-01-27 | 2022-08-23 | David Akselrod | Orthodontic braces and feet orthotics with backscatter based sensors |
| KR101847334B1 (ko) * | 2017-02-02 | 2018-04-10 | 한국기초과학지원연구원 | 형광 이미지 획득 장치 및 방법 |
| GB201701829D0 (en) * | 2017-02-03 | 2017-03-22 | Norwegian Univ Of Science And Tech (Ntnu) | Device |
| CA3052809A1 (en) * | 2017-02-08 | 2018-08-23 | Essenlix Corporation | Qmax assays and applications |
| CA3056765C (en) * | 2017-03-17 | 2024-04-02 | Apton Biosystems, Inc. | Sequencing and high resolution imaging |
| KR102657576B1 (ko) * | 2017-03-20 | 2024-04-12 | 엠쥐아이 테크 컴퍼니 엘티디. | 생물학적 또는 화학적 분석을 위한 바이오센서 및 그 제조 방법 |
| US10508296B2 (en) | 2017-04-25 | 2019-12-17 | Roswell Biotechnologies, Inc. | Enzymatic circuits for molecular sensors |
| CA3057151A1 (en) | 2017-04-25 | 2018-11-01 | Roswell Biotechnologies, Inc. | Enzymatic circuits for molecular sensors |
| JP7356909B2 (ja) | 2017-05-05 | 2023-10-05 | クアンタム－エスアイ インコーポレイテッド | 生物学的反応における表面反応性と防汚特性が改変された基板 |
| EP3622086A4 (en) | 2017-05-09 | 2021-04-21 | Roswell Biotechnologies, Inc | LINK PROBE CIRCUITS FOR MOLECULAR SENSORS |
| KR102387341B1 (ko) * | 2017-05-23 | 2022-04-15 | 하마마츠 포토닉스 가부시키가이샤 | 배향 특성 측정 방법, 배향 특성 측정 프로그램, 및 배향 특성 측정 장치 |
| EP3639013A4 (en) * | 2017-06-16 | 2021-06-30 | Duke University | Resonator networks for improved label detection, computation, analyte sensing, and tunable random number generation |
| CN109103090B (zh) * | 2017-06-21 | 2020-12-04 | 清华大学 | 纳米带的制备方法 |
| KR102083396B1 (ko) * | 2017-06-28 | 2020-03-02 | 주식회사 파나진 | 양자점을 분산광원으로 하는 표적 핵산 검출 방법 |
| CN107390172B (zh) * | 2017-07-17 | 2020-04-28 | 北京大学 | 一种无接触感知定位方法 |
| BR112020000826A2 (pt) | 2017-07-24 | 2020-07-21 | Quantum-Si Incorporated | instrumento bio-optoeletrônico maciçamente paralelo portátil |
| JP7212030B2 (ja) * | 2017-07-24 | 2023-01-24 | クアンタム－エスアイ インコーポレイテッド | 光拒絶フォトニック構造 |
| CN107402199B (zh) * | 2017-07-31 | 2019-09-10 | 京东方科技集团股份有限公司 | 基因测序芯片及其测序方法以及基因测序装置 |
| EP3669018A4 (en) | 2017-08-18 | 2021-05-26 | Nautilus Biotechnology, Inc. | Binding reagent selection methods |
| CN111373049A (zh) | 2017-08-30 | 2020-07-03 | 罗斯威尔生命技术公司 | 用于dna数据存储的进行性酶分子电子传感器 |
| US10784103B2 (en) | 2017-09-19 | 2020-09-22 | Mgi Tech Co., Ltd. | Water level sequencing flow cell fabrication |
| US11100404B2 (en) | 2017-10-10 | 2021-08-24 | Roswell Biotechnologies, Inc. | Methods, apparatus and systems for amplification-free DNA data storage |
| EP3501651B1 (en) * | 2017-12-22 | 2024-03-06 | IMEC vzw | Microfluidic routing |
| AU2019205383B8 (en) * | 2018-01-08 | 2023-09-28 | Quantum-Si Incorporated | System and methods for electrokinetic loading of sub-micron-scale reaction chambers |
| CA3065934A1 (en) * | 2018-01-08 | 2019-07-11 | Illumina, Inc. | High-throughput sequencing with semiconductor-based detection |
| CN108197052B (zh) * | 2018-01-17 | 2021-02-26 | 上海聚星仪器有限公司 | 一种新型测试测量仪器 |
| CA3088687A1 (en) | 2018-01-26 | 2019-08-01 | Quantum-Si Incorporated | Machine learning enabled pulse and base calling for sequencing devices |
| IT201800004146A1 (it) * | 2018-03-30 | 2019-09-30 | St Microelectronics Srl | Apparecchio di analisi di molecole tramite rilevamento di segnali fluorescenti e relativo metodo |
| US10965102B2 (en) * | 2018-04-12 | 2021-03-30 | Samsung Electronics Co., Ltd. | Structured light projector and electronic apparatus including the same |
| WO2019241733A1 (en) | 2018-06-15 | 2019-12-19 | Quantum-Si Incorporated | Data acquisition control for advanced analytic instruments having pulsed optical sources |
| EP3581919B1 (en) * | 2018-06-15 | 2022-03-23 | IMEC vzw | An imaging apparatus and a method for imaging an object |
| KR102546320B1 (ko) * | 2018-06-18 | 2023-06-22 | 삼성전자주식회사 | 구조광 프로젝터 및 이를 포함하는 전자 장치 |
| WO2019246328A1 (en) | 2018-06-22 | 2019-12-26 | Quantum-Si Incorporated | Integrated photodetector with charge storage bin of varied detection time |
| WO2020023496A1 (en) * | 2018-07-23 | 2020-01-30 | The University Of Chicago | Resonator-based ion-selective sensor |
| MX2021002414A (es) * | 2018-08-29 | 2021-04-28 | Quantum Si Inc | Sistema y metodos para la deteccion de vida util usando fotodetectores de conteo de fotones. |
| WO2020047272A1 (en) * | 2018-08-29 | 2020-03-05 | Quantum-Si Incorporated | Sample well fabrication techniques and structures for integrated sensor devices |
| JP6906489B2 (ja) | 2018-09-14 | 2021-07-21 | 株式会社東芝 | ケミカルセンサキット及び分析方法 |
| US11509116B2 (en) * | 2018-10-23 | 2022-11-22 | Analog Photonics LLC | Athermal angular output by combining a laser with a grating based antenna |
| CN111135878B (zh) | 2018-11-06 | 2021-10-15 | 京东方科技集团股份有限公司 | 微流体通道结构及制作方法、微流体检测装置及使用方法 |
| WO2020094233A1 (de) * | 2018-11-08 | 2020-05-14 | Diamontech Ag | Vorrichtung und verfahren zum analysieren eines stoffs |
| KR20250162948A (ko) | 2018-11-15 | 2025-11-19 | 퀀텀-에스아이 인코포레이티드 | 단백질 시퀀싱을 위한 방법 및 조성물 |
| CN113316638A (zh) | 2018-11-20 | 2021-08-27 | 诺迪勒思生物科技公司 | 亲和试剂的设计和选择 |
| JP2020085666A (ja) * | 2018-11-26 | 2020-06-04 | ソニーセミコンダクタソリューションズ株式会社 | 生体由来物質検出用チップ、生体由来物質検出装置及び生体由来物質検出システム |
| US12179204B2 (en) | 2018-12-03 | 2024-12-31 | Quantum-Si Incorporated | Sample well fabrication techniques and structures for integrated sensor |
| CA3124120A1 (en) | 2018-12-20 | 2020-06-25 | Alveo Technologies, Inc. | Handheld impedance-based diagnostic test system for detecting analytes |
| TW202041847A (zh) * | 2019-01-03 | 2020-11-16 | 美商寬騰矽公司 | 用於傳遞光至光子元件之陣列的光學波導及耦合器 |
| TWI687687B (zh) * | 2019-01-11 | 2020-03-11 | 國立中正大學 | 雙光柵感測器、檢測方法及其製備方法 |
| WO2020180426A1 (en) * | 2019-03-04 | 2020-09-10 | Immunolight, Llc. | Energy augmentation structures, energy emitters or energy collectors containing the same, and their use in methods and systems for treating cell proliferation disorders |
| KR20210132176A (ko) | 2019-03-05 | 2021-11-03 | 퀀텀-에스아이 인코포레이티드 | 통합 디바이스를 위한 광학 흡수 필터 |
| WO2020181362A1 (en) | 2019-03-08 | 2020-09-17 | Infinite Potential Laboratories Lp | Quantum control devices and methods |
| CN113597558B (zh) * | 2019-03-20 | 2024-12-10 | 启正生命科学有限公司 | 用于验证生物分析仪的标准材料组合物和使用其的标准条带 |
| WO2020210981A1 (en) | 2019-04-16 | 2020-10-22 | Boe Technology Group Co., Ltd. | Micro-channel device and manufacturing method thereof and micro-fluidic system |
| CA3135206A1 (en) | 2019-04-29 | 2020-11-05 | Pierre Indermuhle | Methods and systems for integrated on-chip single-molecule detection |
| CN110066723A (zh) * | 2019-05-05 | 2019-07-30 | 京东方科技集团股份有限公司 | 基因测序芯片、设备、制造方法 |
| MX2021015497A (es) | 2019-06-14 | 2022-04-18 | Quantum Si Inc | Acoplador de rejilla cortada con mayor sensibilidad de alineación del haz. |
| US11085878B2 (en) | 2019-06-18 | 2021-08-10 | Eagle Technology, Llc | Radiation detection system with surface plasmon resonance detection and related methods |
| CN110229747A (zh) * | 2019-06-18 | 2019-09-13 | 京东方科技集团股份有限公司 | 基因测序芯片、设备及制备方法 |
| US11009611B2 (en) | 2019-06-18 | 2021-05-18 | Eagle Technology, Llc | Radiation detection system with surface plasmon resonance detection and related methods |
| AU2020297509A1 (en) | 2019-06-19 | 2022-01-27 | Quantum-Si Incorporated | Optical nanostructure rejecter for an integrated device and related methods |
| US11793399B2 (en) | 2019-06-20 | 2023-10-24 | Cilag Gmbh International | Super resolution and color motion artifact correction in a pulsed hyperspectral imaging system |
| US11280737B2 (en) * | 2019-06-20 | 2022-03-22 | Cilag Gmbh International | Super resolution and color motion artifact correction in a pulsed fluorescence imaging system |
| WO2020262092A1 (ja) * | 2019-06-26 | 2020-12-30 | ソニー株式会社 | 光学測定装置及び光学測定システム |
| JP2022539633A (ja) * | 2019-07-08 | 2022-09-13 | イルミナ インコーポレイテッド | 光検出デバイス上の光結合構造による導波路統合 |
| MX2022001614A (es) | 2019-08-08 | 2022-05-26 | Quantum Si Inc | Eficiencia mejorada de recolección de emisiones en dispositivos ópticos integrados. |
| WO2021041874A1 (en) | 2019-08-29 | 2021-03-04 | Martin David C | Biofunctional thiophene monomers |
| WO2021045900A1 (en) | 2019-09-06 | 2021-03-11 | Roswell Biotechnologies, Inc. | Methods of fabricating nanoscale structures usable in molecular sensors and other devices |
| US10957731B1 (en) | 2019-10-04 | 2021-03-23 | Visera Technologies Company Limited | Sensor device and method for manufacturing the same |
| US11630062B2 (en) * | 2019-10-10 | 2023-04-18 | Visera Technologies Company Limited | Biosensor and method of forming the same |
| US11705472B2 (en) | 2019-10-10 | 2023-07-18 | Visera Technologies Company Limited | Biosensor and method of distinguishing a light |
| US11105745B2 (en) | 2019-10-10 | 2021-08-31 | Visera Technologies Company Limited | Biosensor |
| KR20220079943A (ko) | 2019-10-11 | 2022-06-14 | 퀀텀-에스아이 인코포레이티드 | 증기 상에서의 표면 개질 |
| US12011716B2 (en) | 2019-10-29 | 2024-06-18 | Quantum-Si Incorporated | Peristaltic pumping of fluids and associated methods, systems, and devices |
| TWI704342B (zh) * | 2019-11-28 | 2020-09-11 | 雷科股份有限公司 | Aoi(自動光學檢測)應用在雷射蝕薄銅線圈的方法及其設備 |
| KR102351249B1 (ko) * | 2020-01-03 | 2022-01-14 | 한국과학기술원 | 분자 다중 이미징 방법 및 장치 |
| US11703454B2 (en) | 2020-01-03 | 2023-07-18 | Korea Advanced Institute Of Science And Technology | Method and apparatus for multiplexed imaging of spectrally-similar fluorophores |
| US11784416B2 (en) * | 2020-01-06 | 2023-10-10 | Raytheon Company | Tunable radio frequency (RF) absorber and thermal heat spreader |
| EP4088351A1 (en) | 2020-01-14 | 2022-11-16 | Quantum-si Incorporated | Amplitude-modulated laser |
| TW202143465A (zh) | 2020-01-14 | 2021-11-16 | 美商寬騰矽公司 | 用於壽命特性分析之整合感應器 |
| KR20220140523A (ko) | 2020-01-14 | 2022-10-18 | 퀀텀-에스아이 인코포레이티드 | 수명 플러스 스펙트럼 특성화를 위한 센서 |
| WO2021150984A1 (en) * | 2020-01-24 | 2021-07-29 | Deepdivebio, Inc. | Optical array qpcr |
| CN111308530B (zh) * | 2020-02-17 | 2021-12-03 | 中国人民解放军战略支援部队信息工程大学 | 一种基于二维波达方向的短波多站和单星协同直接定位方法 |
| WO2021178438A1 (en) | 2020-03-02 | 2021-09-10 | Quantum-Si Incorporated | Integrated sensor for multi-dimensional signal analysis |
| US11573180B2 (en) | 2020-04-08 | 2023-02-07 | Quantum-Si Incorporated | Integrated sensor with reduced skew |
| CN111533083B (zh) * | 2020-05-08 | 2023-09-05 | 中北大学 | 一种基于石墨烯的微型分子光镊 |
| JP2023527764A (ja) | 2020-05-20 | 2023-06-30 | クアンタム－エスアイ インコーポレイテッド | タンパク質シーケンスのための方法及び組成物 |
| WO2021252800A1 (en) | 2020-06-11 | 2021-12-16 | Nautilus Biotechnology, Inc. | Methods and systems for computational decoding of biological, chemical, and physical entities |
| CN116472302A (zh) * | 2020-07-07 | 2023-07-21 | 特韦斯特生物科学公司 | 用于光引导聚合物合成的装置和方法 |
| WO2022020731A2 (en) * | 2020-07-23 | 2022-01-27 | Life Technologies Corporation | Compositions, systems and methods for biological analysis involving energy transfer dye conjugates and analytes comprising the same |
| US12472492B2 (en) | 2020-08-14 | 2025-11-18 | Alveo Technologies, Inc. | Systems and methods of sample depositing and testing |
| KR102628182B1 (ko) * | 2020-08-28 | 2024-01-24 | 한국과학기술원 | 상호정보량 최소화를 통한 다색 분리 방법 및 장치 |
| EP3961194B1 (en) | 2020-08-25 | 2023-11-08 | Korea Advanced Institute of Science and Technology | Method and apparatus for multiplexed imaging of biomolecules through iterative unmixing of fluorophore signals |
| KR102423723B1 (ko) * | 2020-08-27 | 2022-07-21 | 성균관대학교산학협력단 | 플라즈모닉 우물 기반 핵산 검출장치 및 롤투롤 공정을 이용한 이의 제조방법 |
| GB2599729A (en) * | 2020-10-12 | 2022-04-13 | Sumitomo Chemical Co | Method comprising light emitting marker |
| KR20230097103A (ko) * | 2020-10-27 | 2023-06-30 | 퀀텀-에스아이 인코포레이티드 | 광표백 정보를 이용한 단일 분자 검출 시스템 |
| TWI824273B (zh) * | 2020-12-03 | 2023-12-01 | 仁寶電腦工業股份有限公司 | 天線裝置和配置該天線裝置的方法 |
| JP2023554368A (ja) | 2020-12-15 | 2023-12-27 | クアンタム－エスアイ インコーポレイテッド | 単一分子速度論による分子バーコード分析 |
| CA3203535A1 (en) | 2021-01-21 | 2022-07-28 | Gregory KAPP | Systems and methods for biomolecule preparation |
| CN112837620B (zh) * | 2021-01-22 | 2023-07-04 | 武汉京东方光电科技有限公司 | 柔性显示屏及电子设备 |
| CN112864258B (zh) * | 2021-03-05 | 2025-01-10 | 南京扬字源科技有限公司 | 像素结构、红外图像传感器和电子设备 |
| IL305336B2 (en) | 2021-03-11 | 2025-09-01 | Nautilus Subsidiary Inc | Systems and methods for preserving biomolecules |
| US20230035224A1 (en) * | 2021-05-04 | 2023-02-02 | Pacific Biosciences Of California, Inc. | Arrays of integrated analytical devices with reduced-scale unit cell |
| DE102021111787A1 (de) * | 2021-05-06 | 2022-11-10 | Gesellschaft für angewandte Mikro- und Optoelektronik mit beschränkter Haftung - AMO GmbH | Verfahren zur Herstellung einer Lochblende, Lochblende sowie Verwendung einer Lochblende in einem optischen Aufbau |
| CN112986206B (zh) * | 2021-05-20 | 2021-07-30 | 北京百奥纳芯生物科技有限公司 | 一种检测基因芯片杂交结果的方法 |
| US11703445B2 (en) * | 2021-05-28 | 2023-07-18 | Visera Technologies Company Limited | Biosensor with grating array |
| WO2023038859A1 (en) | 2021-09-09 | 2023-03-16 | Nautilus Biotechnology, Inc. | Characterization and localization of protein modifications |
| AU2022352593A1 (en) | 2021-09-22 | 2024-02-15 | Nautilus Subsidiary, Inc. | Methods and systems for determining polypeptide interactions |
| EP4416491A1 (en) * | 2021-10-11 | 2024-08-21 | Quantum-Si Incorporated | Light coupling device |
| US20230149883A1 (en) | 2021-11-03 | 2023-05-18 | Nautilus Biotechnology, Inc. | Systems and methods for surface structuring |
| US20230152211A1 (en) * | 2021-11-11 | 2023-05-18 | California Institute Of Technology | System for Optically Analyzing a Test Sample and Method Therefor |
| WO2023114209A1 (en) * | 2021-12-14 | 2023-06-22 | Quantum-Si Incorporated | Methods for loading and data acquisition |
| EP4463694A1 (en) * | 2022-01-12 | 2024-11-20 | Quantum-Si Incorporated | Labeled binding reagents and methods of use thereof |
| US11924963B2 (en) | 2022-02-03 | 2024-03-05 | Raytheon Company | Printed-circuit isolation barrier for co-site interference mitigation |
| CN119053846A (zh) * | 2022-02-28 | 2024-11-29 | 生物辐射实验室股份有限公司 | 宽谱分析系统 |
| CA3245990A1 (en) | 2022-03-29 | 2023-10-05 | Nautilus Subsidiary Inc | INTEGRATED NETWORKS FOR SINGLE-ANALYTE PROCESSES |
| EP4500124A2 (en) * | 2022-03-29 | 2025-02-05 | Pattern Computer, Inc. | System and method for spectral-based disease detection |
| US20250376716A1 (en) | 2022-06-21 | 2025-12-11 | Nautilus Subsidiary, Inc. | Method for detecting analytes at sites of optically non-resolvable distances |
| US12353011B2 (en) * | 2022-06-27 | 2025-07-08 | Taiwan Semiconductor Manufacturing Co., Ltd. | Photonic package and method of manufacture |
| WO2024073599A1 (en) | 2022-09-29 | 2024-04-04 | Nautilus Subsidiary, Inc. | Preparation of array surfaces for single-analyte processes |
| EP4379355A1 (en) * | 2022-11-29 | 2024-06-05 | Gnothis Holding AG | High throughput analysis of single molecule events |
| WO2024124073A1 (en) | 2022-12-09 | 2024-06-13 | Nautilus Subsidiary, Inc. | A method comprising performing on a single-analyte array at least 50 cycles of a process |
| US12109019B2 (en) | 2022-12-15 | 2024-10-08 | Adaptyx Biosciences, Inc. | Systems and methods for analyte detection |
| WO2024130000A1 (en) | 2022-12-15 | 2024-06-20 | Nautilus Subsidiary, Inc. | Inhibition of photon phenomena on single molecule arrays |
| AU2024232531A1 (en) * | 2023-03-09 | 2025-09-18 | University Of Cincinnati | Optical aptamer biosensors for in-vivo sensing |
| WO2024206122A1 (en) | 2023-03-24 | 2024-10-03 | Nautilus Subsidiary, Inc. | Improved transfer of nanoparticles to array surfaces |
| WO2024213741A1 (en) | 2023-04-13 | 2024-10-17 | Lucas Meyer Cosmetics | Emulsifying agent based on lignin fraction and uses thereof |
| WO2024229244A2 (en) * | 2023-05-03 | 2024-11-07 | Mirvie, Inc. | Methods and systems for determining a pregnancy-related state of a subject |
| US20240394902A1 (en) | 2023-05-24 | 2024-11-28 | Nautilus Subsidiary, Inc. | Systems and methods for machine vision |
| US12373188B2 (en) | 2023-07-06 | 2025-07-29 | Bank Of America Corporation | Systems, methods, and apparatuses for improving computer energy consumption and computer processing by implementing a pluggable carbon emission gateway |
| ES2958785B2 (es) * | 2023-07-17 | 2024-07-24 | Univ Valencia Politecnica | Dispositivo de medida para el analisis de la respuesta optica de materiales biosensibles difractivos |
| US20250066841A1 (en) | 2023-08-24 | 2025-02-27 | Nautilus Subsidiary, Inc. | Compositions and methods for detecting binding interactions under equilibrium or non-equilibrium conditions |
| WO2025047492A1 (ja) * | 2023-08-30 | 2025-03-06 | 富士フイルム株式会社 | 測定装置 |
| WO2025094175A1 (en) * | 2023-10-29 | 2025-05-08 | B.G. Negev Technologies And Applications Ltd. | All optical single photon detector |
| WO2025128588A1 (en) | 2023-12-11 | 2025-06-19 | Nautilus Subsidiary, Inc. | Methods and compositions of particle-based arrays |
| US20250205706A1 (en) | 2023-12-20 | 2025-06-26 | Nautilus Subsidiary, Inc. | Fluidic devices for single-analyte assays |
| WO2025199236A1 (en) | 2024-03-22 | 2025-09-25 | Nautilus Subsidiary, Inc. | Plasmonic particle systems for single-analyte assays |
| WO2025212338A1 (en) | 2024-04-01 | 2025-10-09 | Nautilus Subsidiary, Inc. | Nanostructures for modulation of analyte conformation |
Family Cites Families (208)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5006716A (en) | 1989-02-22 | 1991-04-09 | Research Corporation Technologies, Inc. | Method and system for directional, enhanced fluorescence from molecular layers |
| US5198543A (en) | 1989-03-24 | 1993-03-30 | Consejo Superior Investigaciones Cientificas | PHI29 DNA polymerase |
| US5302509A (en) | 1989-08-14 | 1994-04-12 | Beckman Instruments, Inc. | Method for sequencing polynucleotides |
| WO1991006678A1 (en) | 1989-10-26 | 1991-05-16 | Sri International | Dna sequencing |
| JP3018687B2 (ja) * | 1991-12-12 | 2000-03-13 | 松下電器産業株式会社 | 走査型レーザー顕微鏡 |
| US5355215A (en) * | 1992-09-30 | 1994-10-11 | Environmental Research Institute Of Michigan | Method and apparatus for quantitative fluorescence measurements |
| IL108497A0 (en) | 1993-02-01 | 1994-05-30 | Seq Ltd | Methods and apparatus for dna sequencing |
| JP3169742B2 (ja) * | 1993-06-18 | 2001-05-28 | 松下電器産業株式会社 | 光分岐装置および光ディスク装置 |
| US5495462A (en) * | 1993-06-18 | 1996-02-27 | Matsushita Electric Industrial Co., Ltd. | Light beam splitting apparatus |
| JPH07182686A (ja) * | 1993-12-21 | 1995-07-21 | Matsushita Electric Ind Co Ltd | 光モード変換装置および光分岐装置 |
| US5471515A (en) | 1994-01-28 | 1995-11-28 | California Institute Of Technology | Active pixel sensor with intra-pixel charge transfer |
| US6570617B2 (en) | 1994-01-28 | 2003-05-27 | California Institute Of Technology | CMOS active pixel sensor type imaging system on a chip |
| WO1995033197A1 (en) | 1994-05-27 | 1995-12-07 | Ciba-Geigy Ag | Process for detecting evanescently excited luminescence |
| US5912155A (en) | 1994-09-30 | 1999-06-15 | Life Technologies, Inc. | Cloned DNA polymerases from Thermotoga neapolitana |
| US5814565A (en) | 1995-02-23 | 1998-09-29 | University Of Utah Research Foundation | Integrated optic waveguide immunosensor |
| US6261797B1 (en) | 1996-01-29 | 2001-07-17 | Stratagene | Primer-mediated polynucleotide synthesis and manipulation techniques |
| US5990506A (en) | 1996-03-20 | 1999-11-23 | California Institute Of Technology | Active pixel sensors with substantially planarized color filtering elements |
| EP0938656B1 (de) | 1996-11-18 | 2005-10-26 | Novartis AG | Messvorrichtung mit einem planaren optischen wellenleiter |
| EP1009802B1 (en) | 1997-02-12 | 2004-08-11 | Eugene Y. Chan | Methods for analyzimg polymers |
| EP0983364B1 (en) | 1997-03-12 | 2002-06-12 | PE Corporation (NY) | Dna polymerases having improved labeled nucleotide incorporation properties |
| US6327410B1 (en) | 1997-03-14 | 2001-12-04 | The Trustees Of Tufts College | Target analyte sensors utilizing Microspheres |
| US6825921B1 (en) | 1999-11-10 | 2004-11-30 | Molecular Devices Corporation | Multi-mode light detection system |
| EP0921196A1 (en) | 1997-12-02 | 1999-06-09 | Roche Diagnostics GmbH | Modified DNA-polymerase from carboxydothermus hydrogenoformans and its use for coupled reverse transcription and polymerase chain reaction |
| JPH11173987A (ja) | 1997-12-12 | 1999-07-02 | Hamamatsu Photonics Kk | マイクロタイタビューア |
| DE19810879A1 (de) | 1998-03-13 | 1999-09-16 | Roche Diagnostics Gmbh | Polymerasenchimären |
| WO1999049082A2 (en) | 1998-03-23 | 1999-09-30 | Invitrogen Corporation | Modified nucleotides and methods useful for nucleic acid sequencing |
| CA2330673C (en) | 1998-05-01 | 2009-05-26 | Arizona Board Of Regents | Method of determining the nucleotide sequence of oligonucleotides and dna molecules |
| US7875440B2 (en) | 1998-05-01 | 2011-01-25 | Arizona Board Of Regents | Method of determining the nucleotide sequence of oligonucleotides and DNA molecules |
| GB9810350D0 (en) | 1998-05-14 | 1998-07-15 | Ciba Geigy Ag | Organic compounds |
| JP2000004871A (ja) | 1998-06-29 | 2000-01-11 | Olympus Optical Co Ltd | 培養容器、及び培養容器内の試料を観察する顕微鏡 |
| US6787308B2 (en) | 1998-07-30 | 2004-09-07 | Solexa Ltd. | Arrayed biomolecules and their use in sequencing |
| US6716394B2 (en) | 1998-08-11 | 2004-04-06 | Caliper Technologies Corp. | DNA sequencing using multiple fluorescent labels being distinguishable by their decay times |
| US6210896B1 (en) | 1998-08-13 | 2001-04-03 | Us Genomics | Molecular motors |
| US6280939B1 (en) | 1998-09-01 | 2001-08-28 | Veeco Instruments, Inc. | Method and apparatus for DNA sequencing using a local sensitive force detector |
| ATE319857T1 (de) | 1998-12-14 | 2006-03-15 | Li Cor Inc | Kit und methode zur nukleinsäuresequenzierung einzelner moleküle durch polymerase synthese |
| US6134002A (en) * | 1999-01-14 | 2000-10-17 | Duke University | Apparatus and method for the rapid spectral resolution of confocal images |
| ES2310514T3 (es) | 1999-03-10 | 2009-01-16 | Asm Scientific, Inc. | Un metodo para la secuenciacion directa de acido nucleico. |
| GB9906929D0 (en) * | 1999-03-26 | 1999-05-19 | Univ Glasgow | Assay system |
| US7056661B2 (en) | 1999-05-19 | 2006-06-06 | Cornell Research Foundation, Inc. | Method for sequencing nucleic acid molecules |
| EP1681357A3 (en) | 1999-05-19 | 2006-07-26 | Cornell Research Foundation, Inc. | Method for sequencing nucleic acid molecules |
| US6137117A (en) | 1999-06-21 | 2000-10-24 | The United States Of America As Represented By The Secretary Of The Navy | Integrating multi-waveguide sensor |
| FR2797053B1 (fr) * | 1999-07-13 | 2001-08-31 | Commissariat Energie Atomique | Support d'analyse a transmission de lumiere de fluorescence |
| US6596483B1 (en) * | 1999-11-12 | 2003-07-22 | Motorola, Inc. | System and method for detecting molecules using an active pixel sensor |
| US6399335B1 (en) | 1999-11-16 | 2002-06-04 | Advanced Research And Technology Institute, Inc. | γ-phosphoester nucleoside triphosphates |
| DE50006533D1 (de) * | 1999-12-17 | 2004-06-24 | Zeptosens Ag Witterswil | Anordnung von probenbehältnissen und deren verwendung zur multianalytbestimmung |
| JP3978307B2 (ja) * | 2000-02-09 | 2007-09-19 | 株式会社日立製作所 | 紫外レーザ光発生装置並びに欠陥検査装置およびその方法 |
| US6704104B2 (en) * | 2000-03-16 | 2004-03-09 | Spectrumedix Llc | Multi-wavelength array reader for biological assay |
| JP2003532123A (ja) * | 2000-04-28 | 2003-10-28 | エッジライト バイオサイエンシズ インコーポレイテッド | マイクロアレーエバネッセント波蛍光検出装置 |
| US6917726B2 (en) * | 2001-09-27 | 2005-07-12 | Cornell Research Foundation, Inc. | Zero-mode clad waveguides for performing spectroscopy with confined effective observation volumes |
| US6936702B2 (en) | 2000-06-07 | 2005-08-30 | Li-Cor, Inc. | Charge-switch nucleotides |
| EP1287154A4 (en) | 2000-06-07 | 2010-12-15 | Pacific Biosciences California | NUCLEOTIDES WITH CHARGE SWITCHING |
| EP1311824A4 (en) | 2000-06-25 | 2010-12-08 | Affymetrix Inc | OPTICALLY ACTIVE SUBSTRATES |
| US7277166B2 (en) | 2000-08-02 | 2007-10-02 | Honeywell International Inc. | Cytometer analysis cartridge optical configuration |
| FR2813121A1 (fr) | 2000-08-21 | 2002-02-22 | Claude Weisbuch | Dispositif perfectionne de support d'elements chromophores |
| EP1320596A4 (en) | 2000-08-30 | 2005-01-12 | Univ Rochester | REVERSE TRANSCRIPTION REACTION METHOD USING REVERSE TRANSCRIPTASE CODED BY RETROTRANSPOSON NON-LTR |
| AU2001284681A1 (en) | 2000-09-11 | 2002-03-26 | The Government Of The United States Of America, As Represented By The Secretary Of The Navy | Fluidics system |
| AU2001210599A1 (en) | 2000-10-23 | 2002-05-06 | Diachip Limited | High precision and intellectual biochip arrayer having function of respotting |
| JP3695340B2 (ja) * | 2001-03-30 | 2005-09-14 | 株式会社日立製作所 | Ｄｎａ検査方法及びその装置並びに蛍光検出方法 |
| AU2002258997A1 (en) | 2001-04-24 | 2002-11-05 | Li-Cor, Inc. | Polymerases with charge-switch activity and methods of generating such polymerases |
| US7223541B2 (en) | 2001-08-29 | 2007-05-29 | Ge Healthcare Bio-Sciences Corp. | Terminal-phosphate-labeled nucleotides and methods of use |
| US7256019B2 (en) | 2001-08-29 | 2007-08-14 | Ge Healthcare Bio-Sciences Corp. | Terminal phosphate blocked nucleoside polyphosphates |
| US7727722B2 (en) | 2001-08-29 | 2010-06-01 | General Electric Company | Ligation amplification |
| DE60235376D1 (de) | 2001-08-29 | 2010-04-01 | Ge Healthcare Bio Sciences | Markierte nukleosidpolyphosphate |
| US7033762B2 (en) | 2001-08-29 | 2006-04-25 | Amersham Biosciences Corp | Single nucleotide amplification and detection by polymerase |
| US7052839B2 (en) | 2001-08-29 | 2006-05-30 | Amersham Biosciences Corp | Terminal-phosphate-labeled nucleotides and methods of use |
| US7244566B2 (en) | 2001-08-29 | 2007-07-17 | Ge Healthcare Bio-Sciences Corp. | Analyte detection |
| WO2003020488A1 (de) * | 2001-08-30 | 2003-03-13 | Zeptosens Ag | Verfahren zur herstellung von abformkörpern, insbesondere optischen strukturen, und deren verwendung |
| US20070020622A1 (en) | 2001-09-14 | 2007-01-25 | Invitrogen Corporation | DNA Polymerases and mutants thereof |
| US7057026B2 (en) | 2001-12-04 | 2006-06-06 | Solexa Limited | Labelled nucleotides |
| US7179654B2 (en) | 2002-03-18 | 2007-02-20 | Agilent Technologies, Inc. | Biochemical assay with programmable array detection |
| US6924887B2 (en) | 2002-03-27 | 2005-08-02 | Sarnoff Corporation | Method and apparatus for generating charge from a light pulse |
| US7595883B1 (en) | 2002-09-16 | 2009-09-29 | The Board Of Trustees Of The Leland Stanford Junior University | Biological analysis arrangement and approach therefor |
| WO2004072238A2 (en) | 2003-02-05 | 2004-08-26 | Amersham Biosciences Corp | Terminal-phosphate-labeled nucleotides with new linkers |
| US7745116B2 (en) | 2003-04-08 | 2010-06-29 | Pacific Biosciences Of California, Inc. | Composition and method for nucleic acid sequencing |
| US20040258563A1 (en) | 2003-06-23 | 2004-12-23 | Applera Corporation | Caps for sample wells and microcards for biological materials |
| CN1209619C (zh) | 2003-07-18 | 2005-07-06 | 华中科技大学 | 塑料生物芯片的键合和封装装置 |
| US20050118060A1 (en) * | 2003-08-04 | 2005-06-02 | Irm, Llc | Multi-well container positioning devices and related systems and methods |
| WO2005073407A1 (en) | 2003-10-07 | 2005-08-11 | Ut-Battelle, Llc | Advanced integrated circuit biochip |
| US20050079102A1 (en) | 2003-10-14 | 2005-04-14 | Staton Kenneth L. | Interrogation apparatus |
| US7169560B2 (en) | 2003-11-12 | 2007-01-30 | Helicos Biosciences Corporation | Short cycle methods for sequencing polynucleotides |
| US20070281288A1 (en) | 2004-01-27 | 2007-12-06 | Shimshon Belkin | Method and System for Detecting Analytes |
| DE602005020421D1 (de) | 2004-02-19 | 2010-05-20 | Helicos Biosciences Corp | Verfahren zur analyse von polynukleotidsequenzen |
| US7462452B2 (en) | 2004-04-30 | 2008-12-09 | Pacific Biosciences Of California, Inc. | Field-switch sequencing |
| EP1786932A4 (en) * | 2004-08-23 | 2010-10-27 | Us Genomics Inc | SYSTEMS AND METHOD FOR THE DETECTION AND ANALYSIS OF POLYMERS |
| US7170050B2 (en) | 2004-09-17 | 2007-01-30 | Pacific Biosciences Of California, Inc. | Apparatus and methods for optical analysis of molecules |
| EP1790202A4 (en) | 2004-09-17 | 2013-02-20 | Pacific Biosciences California | APPARATUS AND METHOD FOR ANALYZING MOLECULES |
| US8293430B2 (en) * | 2005-01-27 | 2012-10-23 | Applied Materials, Inc. | Method for etching a molybdenum layer suitable for photomask fabrication |
| US7345764B2 (en) | 2005-02-07 | 2008-03-18 | Vladimir Bulovic | Apparatus and method for a slim format spectrometer |
| US20060223067A1 (en) | 2005-03-31 | 2006-10-05 | Paolo Vatta | Mutant DNA polymerases and methods of use |
| US7738086B2 (en) | 2005-05-09 | 2010-06-15 | The Trustees Of Columbia University In The City Of New York | Active CMOS biosensor chip for fluorescent-based detection |
| CN100401041C (zh) * | 2005-06-09 | 2008-07-09 | 上海交通大学 | 光波导吸收式气体传感器及测量系统 |
| US7645866B2 (en) | 2005-06-28 | 2010-01-12 | Life Technologies Corporation | Methods of producing and sequencing modified polynucleotides |
| EP1919930B1 (en) | 2005-07-01 | 2016-09-14 | Dako Denmark A/S | New nucleic acid base pairs |
| US7426322B2 (en) | 2005-07-20 | 2008-09-16 | Searete Llc. | Plasmon photocatalysis |
| US20160355869A1 (en) * | 2005-08-02 | 2016-12-08 | University Of Utah Research Foundation | Biosensors including metallic nanocavities |
| JP2009503548A (ja) * | 2005-08-02 | 2009-01-29 | ユニバーシティ・オブ・ユタ・リサーチ・ファウンデイション | 金属ナノキャビティを含むバイオセンサー |
| US7453916B2 (en) * | 2005-09-08 | 2008-11-18 | Intel Corporation | High throughput optical micro-array reader capable of variable pitch and spot size array processing for genomics and proteomics |
| US7405281B2 (en) | 2005-09-29 | 2008-07-29 | Pacific Biosciences Of California, Inc. | Fluorescent nucleotide analogs and uses therefor |
| TWI296044B (en) * | 2005-11-03 | 2008-04-21 | Ind Tech Res Inst | Coupled waveguide-surface plasmon resonance biosensor |
| WO2007070542A2 (en) | 2005-12-12 | 2007-06-21 | The Government Of The United States Of America As Represented By The Secretary Of The Deptartment Ofhealth And Human Services | Nanoprobes for detection or modification of molecules |
| EP3056575B1 (en) | 2005-12-22 | 2017-10-11 | Pacific Biosciences Of California, Inc. | Polymerases for nucleotide analogue incorporation |
| AU2006331512B2 (en) | 2005-12-22 | 2012-02-23 | Pacific Biosciences Of California, Inc. | Active surface coupled polymerases |
| US7692783B2 (en) | 2006-02-13 | 2010-04-06 | Pacific Biosciences Of California | Methods and systems for simultaneous real-time monitoring of optical signals from multiple sources |
| US7995202B2 (en) | 2006-02-13 | 2011-08-09 | Pacific Biosciences Of California, Inc. | Methods and systems for simultaneous real-time monitoring of optical signals from multiple sources |
| US7715001B2 (en) | 2006-02-13 | 2010-05-11 | Pacific Biosciences Of California, Inc. | Methods and systems for simultaneous real-time monitoring of optical signals from multiple sources |
| US8975216B2 (en) | 2006-03-30 | 2015-03-10 | Pacific Biosciences Of California | Articles having localized molecules disposed thereon and methods of producing same |
| US20080050747A1 (en) | 2006-03-30 | 2008-02-28 | Pacific Biosciences Of California, Inc. | Articles having localized molecules disposed thereon and methods of producing and using same |
| US7750316B2 (en) * | 2006-05-10 | 2010-07-06 | Dublin City University | Polymer biochip for detecting fluorescence |
| EP2021113A2 (en) | 2006-05-11 | 2009-02-11 | Raindance Technologies, Inc. | Microfluidic devices |
| DE102006030541B4 (de) | 2006-06-23 | 2010-05-12 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Optische Anordnung |
| US8207509B2 (en) | 2006-09-01 | 2012-06-26 | Pacific Biosciences Of California, Inc. | Substrates, systems and methods for analyzing materials |
| EP3936857B1 (en) | 2006-09-01 | 2023-06-21 | Pacific Biosciences Of California, Inc. | Substrates, systems and methods for analyzing materials |
| CA2666517A1 (en) | 2006-10-23 | 2008-05-02 | Pacific Biosciences Of California, Inc. | Polymerase enzymes and reagents for enhanced nucleic acid sequencing |
| US9218944B2 (en) * | 2006-10-30 | 2015-12-22 | Applied Materials, Inc. | Mask etch plasma reactor having an array of optical sensors viewing the workpiece backside and a tunable element controlled in response to the optical sensors |
| FR2908888B1 (fr) | 2006-11-21 | 2012-08-03 | Centre Nat Rech Scient | Dispositif pour la detection exaltee de l'emission d'une particule cible |
| WO2008114148A2 (en) | 2007-03-22 | 2008-09-25 | Universite Louis Pasteur | Device for sorting and concentrating electromagnetic energy and apparatus comprising at least one such device |
| EP2134871B1 (en) | 2007-03-30 | 2012-03-07 | Pacific Biosciences of California, Inc. | Systems and methods for enhancing fluorescent signals |
| JP5222599B2 (ja) * | 2007-07-20 | 2013-06-26 | 株式会社日立ハイテクノロジーズ | 核酸分析デバイス及びそれを用いた核酸分析装置 |
| JP2009022247A (ja) * | 2007-07-23 | 2009-02-05 | Toshiba Corp | 培養容器及び培養組織回収方法 |
| US9410892B2 (en) * | 2007-08-30 | 2016-08-09 | Cornell University | Nanoscale optofluidic devices for molecular detection |
| EP2212679A1 (en) * | 2007-09-18 | 2010-08-04 | Applied Biosystems Inc. | Methods, systems and apparatus for light concentrating mechanisms |
| US7873085B2 (en) | 2007-10-23 | 2011-01-18 | Andrei Babushkin | Method and device for controlling optical output of laser diode |
| GB0723725D0 (en) | 2007-12-05 | 2008-01-16 | Ge Healthcare Uk Ltd | Apparatus and method for detecting dna damage |
| WO2009082706A1 (en) | 2007-12-21 | 2009-07-02 | The Trustees Of Columbia University In The City Of New York | Active cmos sensor array for electrochemical biomolecular detection |
| WO2009091847A2 (en) | 2008-01-14 | 2009-07-23 | Life Technologies Corporation | Compositions, methods and systems for single molecule sequencing |
| EP2252625B1 (en) | 2008-02-07 | 2017-12-20 | Pacific Biosciences of California, Inc. | Cis reactive oxygen quenchers integrated into linkers |
| US8652781B2 (en) | 2008-02-12 | 2014-02-18 | Pacific Biosciences Of California, Inc. | Cognate sampling kinetics |
| AU2009215193A1 (en) | 2008-02-12 | 2009-08-20 | Pacific Biosciences Of California, Inc. | Compositions and methods for use in analytical reactions |
| EP2263087B1 (en) | 2008-03-13 | 2017-08-09 | Pacific Biosciences of California, Inc. | Labeled reactants and their uses |
| US20090243584A1 (en) * | 2008-03-25 | 2009-10-01 | Guigen Zhang | Fabrication of microstructures integrated with nanopillars along with their applications as electrodes in sensors |
| US7973146B2 (en) | 2008-03-26 | 2011-07-05 | Pacific Biosciences Of California, Inc. | Engineered fluorescent dye labeled nucleotide analogs for DNA sequencing |
| MX2010010600A (es) | 2008-03-28 | 2011-03-30 | Pacific Biosciences California Inc | Composiciones y metodos para secuenciacion de acidos nucleicos. |
| US8143030B2 (en) | 2008-09-24 | 2012-03-27 | Pacific Biosciences Of California, Inc. | Intermittent detection during analytical reactions |
| US8236499B2 (en) | 2008-03-28 | 2012-08-07 | Pacific Biosciences Of California, Inc. | Methods and compositions for nucleic acid sample preparation |
| US8999676B2 (en) | 2008-03-31 | 2015-04-07 | Pacific Biosciences Of California, Inc. | Recombinant polymerases for improved single molecule sequencing |
| EP2881736B1 (en) | 2008-03-31 | 2017-06-07 | Pacific Biosciences of California, Inc. | Single polymerase molecule loading methods and compositions |
| US9127259B2 (en) | 2008-03-31 | 2015-09-08 | Pacific Biosciences Of California, Inc. | Enzymes resistant to photodamage |
| US8420366B2 (en) | 2008-03-31 | 2013-04-16 | Pacific Biosciences Of California, Inc. | Generation of modified polymerases for improved accuracy in single molecule sequencing |
| CA2720046C (en) | 2008-03-31 | 2018-07-24 | Pacific Biosciences Of California, Inc. | Generation of modified polymerases for improved accuracy in single molecule sequencing |
| US8133672B2 (en) | 2008-03-31 | 2012-03-13 | Pacific Biosciences Of California, Inc. | Two slow-step polymerase enzyme systems and methods |
| US10114213B2 (en) | 2008-04-04 | 2018-10-30 | Cvi Laser, Llc | Laser systems and optical devices for manipulating laser beams |
| JP5268444B2 (ja) * | 2008-06-23 | 2013-08-21 | 株式会社日立ハイテクノロジーズ | 単分子リアルタイムシーケンス装置，核酸分析装置及び単分子リアルタイムシーケンス方法 |
| EP2148187A1 (de) * | 2008-07-25 | 2010-01-27 | Roche Diagnostics GmbH | Anregungs- und Abbildungsoptik für die Fluoreszenzdetektion |
| US7999454B2 (en) * | 2008-08-14 | 2011-08-16 | Global Oled Technology Llc | OLED device with embedded chip driving |
| EP2326733A2 (en) | 2008-09-05 | 2011-06-01 | Pacific Biosciences of California, Inc. | Engineering polymerases and reaction conditions for modified incorporation properties |
| FR2936099A1 (fr) * | 2008-09-12 | 2010-03-19 | Thales Sa | Dispositif de detection d'images ameliore pour un imageur multispectral et imageur multispectral comportant ce dispositif |
| EP3629011B1 (en) | 2008-09-16 | 2023-11-01 | Pacific Biosciences Of California, Inc. | Integrated optical device |
| US8921046B2 (en) | 2008-09-19 | 2014-12-30 | Pacific Biosciences Of California, Inc. | Nucleic acid sequence analysis |
| US8481264B2 (en) | 2008-09-19 | 2013-07-09 | Pacific Biosciences Of California, Inc. | Immobilized nucleic acid complexes for sequence analysis |
| US9156010B2 (en) | 2008-09-23 | 2015-10-13 | Bio-Rad Laboratories, Inc. | Droplet-based assay system |
| US8383369B2 (en) | 2008-09-24 | 2013-02-26 | Pacific Biosciences Of California, Inc. | Intermittent detection during analytical reactions |
| CN102227659B (zh) | 2008-09-30 | 2014-12-24 | 加利福尼亚太平洋生物科学股份有限公司 | 超高多路分析系统和方法 |
| EP2182523B1 (en) | 2008-10-31 | 2013-01-09 | CSEM Centre Suisse d'Electronique et de Microtechnique SA -Recherche et Développement | Charge sampling device and method based on a MOS-transmission line |
| KR101045206B1 (ko) * | 2008-10-31 | 2011-06-30 | 삼성전자주식회사 | 여기광 흡수 도파로가 삽입된 집적된 바이오칩 및 그 제조방법 |
| KR101065077B1 (ko) * | 2008-11-05 | 2011-09-15 | 삼성전자주식회사 | 시료 검출용 기판, 이를 채용한 바이오칩, 시료 검출용 기판의 제조방법 및 바이오 물질 검출장치 |
| WO2010057185A1 (en) | 2008-11-17 | 2010-05-20 | Pacific Biosciences Of California, Inc. | Phospholink nucleotides for sequencing applications |
| US9222082B2 (en) | 2009-01-30 | 2015-12-29 | Oxford Nanopore Technologies Limited | Hybridization linkers |
| US8921280B2 (en) * | 2009-02-11 | 2014-12-30 | Samsung Electronics Co., Ltd. | Integrated bio-chip and method of fabricating the integrated bio-chip |
| WO2010111686A2 (en) | 2009-03-27 | 2010-09-30 | Life Technologies Corp | Labeled enzyme compositions, methods & systems |
| WO2010117420A2 (en) | 2009-03-30 | 2010-10-14 | Pacific Biosciences Of California, Inc. | Fret-labeled compounds and uses therefor |
| JP5707030B2 (ja) * | 2009-04-02 | 2015-04-22 | 株式会社日立ハイテクノロジーズ | 核酸分析デバイス、及び核酸分析装置 |
| US8501406B1 (en) | 2009-07-14 | 2013-08-06 | Pacific Biosciences Of California, Inc. | Selectively functionalized arrays |
| JP5462548B2 (ja) * | 2009-08-12 | 2014-04-02 | 株式会社日立ハイテクノロジーズ | 核酸分析素子及びそれを用いた核酸分析装置 |
| WO2011040971A2 (en) | 2009-09-30 | 2011-04-07 | Pacific Biosciences Of California, Inc. | Generation of modified polymerases for improved accuracy in single molecule sequencing |
| US8278728B2 (en) | 2009-10-17 | 2012-10-02 | Florida Institute Of Technology | Array of concentric CMOS photodiodes for detection and de-multiplexing of spatially modulated optical channels |
| WO2011068569A1 (en) | 2009-12-04 | 2011-06-09 | Biotium, Inc. | Heterocycle-substituted xanthene dyes |
| JP6017107B2 (ja) | 2009-12-28 | 2016-10-26 | ソニー株式会社 | イメージセンサ及びその製造方法、並びにセンサデバイス |
| WO2011090745A1 (en) | 2009-12-29 | 2011-07-28 | Life Technologies Corporation | Single molecule detection and sequencing using fluorescence lifetime imaging |
| CA2790393C (en) | 2010-02-19 | 2019-03-12 | Pacific Biosciences Of California, Inc. | Integrated analytical system and method |
| US8994946B2 (en) | 2010-02-19 | 2015-03-31 | Pacific Biosciences Of California, Inc. | Integrated analytical system and method |
| US9482615B2 (en) * | 2010-03-15 | 2016-11-01 | Industrial Technology Research Institute | Single-molecule detection system and methods |
| TWI466278B (zh) | 2010-04-06 | 2014-12-21 | 勝開科技股份有限公司 | 晶圓級影像感測器構裝結構及其製造方法 |
| US8865077B2 (en) | 2010-06-11 | 2014-10-21 | Industrial Technology Research Institute | Apparatus for single-molecule detection |
| US8865078B2 (en) * | 2010-06-11 | 2014-10-21 | Industrial Technology Research Institute | Apparatus for single-molecule detection |
| EP2439512A1 (en) * | 2010-10-01 | 2012-04-11 | Aqsens Oy | A device for holding a sample |
| EP2441520A1 (en) | 2010-10-12 | 2012-04-18 | Eppendorf AG | Real-time amplification and micro-array based detection of nucleic acid targets in a flow chip assay |
| EP2646154A2 (en) | 2010-11-30 | 2013-10-09 | Quantumdx Group Limited | The design, fabrication and use of a microfluidics multitemperature flexible reaction device |
| EP2647060A2 (en) | 2010-11-30 | 2013-10-09 | Tshwane University Of Technology | Cmos based micro-photonic systems |
| EP2689028B1 (en) | 2011-03-23 | 2017-08-30 | Pacific Biosciences Of California, Inc. | Isolation of polymerase-nucleic acid complexes and loading onto substrates |
| JP2013045857A (ja) | 2011-08-24 | 2013-03-04 | Sony Corp | イメージセンサ及びその製造方法並びに検査装置 |
| FR2982028B1 (fr) | 2011-10-26 | 2020-02-21 | Aryballe Technologies | Puce microstructuree comprenant des surfaces convexes pour analyse par resonance des plasmons de surface, dispositif d'analyse contenant ladite puce microstructuree et utilisation dudit dispositif |
| US8778849B2 (en) | 2011-10-28 | 2014-07-15 | Illumina, Inc. | Microarray fabrication system and method |
| US9606060B2 (en) | 2012-01-13 | 2017-03-28 | California Institute Of Technology | Filterless time-domain detection of one or more fluorophores |
| US8906660B2 (en) | 2012-02-01 | 2014-12-09 | Pacific Biosciences Of California, Inc. | Recombinant polymerases with increased phototolerance |
| EP3590948A1 (en) | 2012-02-15 | 2020-01-08 | Pacific Biosciences of California, Inc. | Polymerase enzyme substrates with protein shield |
| US9059250B2 (en) * | 2012-02-17 | 2015-06-16 | International Business Machines Corporation | Lateral-dimension-reducing metallic hard mask etch |
| EP2831283A4 (en) * | 2012-03-30 | 2015-11-04 | Pacific Biosciences California | METHODS AND COMPOSITION FOR SEQUENCING MODIFIED NUCLEIC ACIDS |
| JP6301311B2 (ja) * | 2012-04-10 | 2018-03-28 | ザ トラスティーズ オブ プリンストン ユニバーシティＴｈｅ Ｔｒｕｓｔｅｅｓ Ｏｆ Ｐｒｉｎｃｅｔｏｎ Ｕｎｉｖｅｒｓｉｔｙ | 超高感度センサ |
| WO2013171197A1 (en) | 2012-05-15 | 2013-11-21 | Ait Austrian Institute Of Technology Gmbh | Compact plasmon-enhanced fluorescence biosensor |
| US9372308B1 (en) * | 2012-06-17 | 2016-06-21 | Pacific Biosciences Of California, Inc. | Arrays of integrated analytical devices and methods for production |
| US8654427B1 (en) | 2012-08-31 | 2014-02-18 | Rosemount Aerospace Inc. | Ruggedized two-axis optical beam steering device |
| EP4123294A1 (en) | 2012-12-18 | 2023-01-25 | Pacific Biosciences Of California, Inc. | An optical analytical device |
| EP2959283B1 (en) * | 2013-02-22 | 2022-08-17 | Pacific Biosciences of California, Inc. | Integrated illumination of optical analytical devices |
| CA2906728C (en) | 2013-03-15 | 2022-07-12 | Nanobiosym, Inc. | Systems and methods for mobile device analysis of nucleic acids and proteins |
| US10933417B2 (en) | 2013-03-15 | 2021-03-02 | Nanobiosym, Inc. | Systems and methods for mobile device analysis of nucleic acids and proteins |
| US9654680B2 (en) * | 2013-10-17 | 2017-05-16 | Canon Kabushiki Kaisha | Image capturing apparatus and control method therefor |
| KR102240166B1 (ko) | 2013-11-17 | 2021-04-14 | 퀀텀-에스아이 인코포레이티드 | 분자들을 프로빙 검출 및 분석하기 위한 외부 광원을 구비한 통합 디바이스 |
| WO2015141873A1 (ko) | 2014-03-18 | 2015-09-24 | 서울대학교산학협력단 | 광영역 시료를 고속 정량 분석하는 라만 분석 방법 및 장치 |
| US9765395B2 (en) | 2014-04-28 | 2017-09-19 | Nanomedical Diagnostics, Inc. | System and method for DNA sequencing and blood chemistry analysis |
| CA2957543A1 (en) | 2014-08-08 | 2016-02-11 | Quantum-Si Incorporated | Optical system and assay chip for probing, detecting and analyzing molecules |
| CN107112333B (zh) | 2014-08-08 | 2020-07-10 | 宽腾矽公司 | 基于入射光子到达时间的识别、成像、测序法及存储介质 |
| EP3194934B1 (en) | 2014-08-08 | 2024-03-06 | Quantum-Si Incorporated | Integrated device for use with an external light source for probing, detecting, and analyzing molecules by luminescence lifetime measurements |
| US9666748B2 (en) | 2015-01-14 | 2017-05-30 | International Business Machines Corporation | Integrated on chip detector and zero waveguide module structure for use in DNA sequencing |
| CN107615121B (zh) | 2015-03-16 | 2021-04-16 | 加利福尼亚太平洋生物科学股份有限公司 | 用于自由空间光耦合的集成装置及系统 |
| US10246742B2 (en) | 2015-05-20 | 2019-04-02 | Quantum-Si Incorporated | Pulsed laser and bioanalytic system |
| US10605730B2 (en) | 2015-05-20 | 2020-03-31 | Quantum-Si Incorporated | Optical sources for fluorescent lifetime analysis |
| CN105039147B (zh) | 2015-06-03 | 2016-05-04 | 西安交通大学 | 一种高通量基因测序碱基荧光图像捕获系统装置及方法 |
| BR112020000826A2 (pt) | 2017-07-24 | 2020-07-21 | Quantum-Si Incorporated | instrumento bio-optoeletrônico maciçamente paralelo portátil |
-
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2020
- 2020-03-05 JP JP2020037466A patent/JP7015336B2/ja not_active Expired - Fee Related
- 2020-06-12 US US16/900,008 patent/US12123834B2/en active Active
- 2020-12-11 AU AU2020286308A patent/AU2020286308B2/en active Active
-
2021
- 2021-02-08 JP JP2021018615A patent/JP7242727B2/ja active Active
-
2022
- 2022-02-18 US US17/676,070 patent/US12163888B2/en active Active
- 2022-03-25 US US17/704,691 patent/US20220214279A1/en not_active Abandoned
- 2022-07-29 US US17/877,837 patent/US20220364996A1/en active Pending
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