JP2013542747A5 - - Google Patents

Download PDF

Info

Publication number
JP2013542747A5
JP2013542747A5 JP2013540104A JP2013540104A JP2013542747A5 JP 2013542747 A5 JP2013542747 A5 JP 2013542747A5 JP 2013540104 A JP2013540104 A JP 2013540104A JP 2013540104 A JP2013540104 A JP 2013540104A JP 2013542747 A5 JP2013542747 A5 JP 2013542747A5
Authority
JP
Japan
Prior art keywords
genetically modified
yeast cell
modified yeast
cell according
gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2013540104A
Other languages
English (en)
Japanese (ja)
Other versions
JP6061862B2 (ja
JP2013542747A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2011/061717 external-priority patent/WO2012074818A2/en
Publication of JP2013542747A publication Critical patent/JP2013542747A/ja
Publication of JP2013542747A5 publication Critical patent/JP2013542747A5/ja
Application granted granted Critical
Publication of JP6061862B2 publication Critical patent/JP6061862B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2013540104A 2010-11-22 2011-11-21 3‐ヒドロキシプロピオン酸生産用の組成物及び方法 Active JP6061862B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US41619910P 2010-11-22 2010-11-22
US61/416,199 2010-11-22
US201161535181P 2011-09-15 2011-09-15
US61/535,181 2011-09-15
PCT/US2011/061717 WO2012074818A2 (en) 2010-11-22 2011-11-21 Compositions and methods for 3-hydroxypropionic acid production

Publications (3)

Publication Number Publication Date
JP2013542747A JP2013542747A (ja) 2013-11-28
JP2013542747A5 true JP2013542747A5 (enExample) 2015-01-15
JP6061862B2 JP6061862B2 (ja) 2017-01-18

Family

ID=45099210

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013540104A Active JP6061862B2 (ja) 2010-11-22 2011-11-21 3‐ヒドロキシプロピオン酸生産用の組成物及び方法

Country Status (11)

Country Link
US (7) US9090918B2 (enExample)
EP (2) EP2643450A2 (enExample)
JP (1) JP6061862B2 (enExample)
KR (1) KR20130119945A (enExample)
CN (2) CN103502432A (enExample)
AU (1) AU2011336923B2 (enExample)
BR (1) BR112013012630B1 (enExample)
CA (1) CA2818499A1 (enExample)
MX (1) MX2013005654A (enExample)
WO (1) WO2012074818A2 (enExample)
ZA (1) ZA201303544B (enExample)

Families Citing this family (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2001992B1 (en) 2006-03-13 2016-07-20 Cargill Inc. Yeast cells having disrupted pathway from dihydroxyacetone phosphate to glycerol
CA2807561C (en) 2010-08-06 2022-04-12 Mascoma Corporation Production of malonyl-coa derived products via anaerobic pathways
CA2885934C (en) * 2010-11-22 2018-05-01 Cargill, Incorporated Compositions and methods for increased ethanol titer from biomass
MX2013005654A (es) 2010-11-22 2013-07-17 Novozymes Inc Composiciones y metodos para la produccion de acido 3-hidroxipropionico.
CA2840525A1 (en) * 2011-06-28 2013-01-03 Brookhaven Science Associates, Llc Modified plants with increased oil content
IN2014CN02136A (enExample) * 2011-08-24 2015-05-29 Novozymes Inc
EP2751261B1 (en) 2011-09-30 2018-08-29 Novozymes, Inc. Dehydrogenase variants and polynucleotides encoding same
CN118086086A (zh) * 2012-03-06 2024-05-28 利戈斯股份有限公司 用于产生丙二酸的重组宿主细胞
KR102098849B1 (ko) * 2012-05-30 2020-04-09 란자테크 뉴질랜드 리미티드 재조합 미생물 및 이의 용도
BR112015002940A2 (pt) 2012-08-10 2018-04-24 Opx Biotechnologies Inc microorganismos e métodos para a produção de ácidos graxos e produtos derivados de ácidos graxos.
JP2015531237A (ja) * 2012-10-11 2015-11-02 テクニカル・ユニヴァーシティ・オブ・デンマーク 遺伝子組換え酵母
JP2015536669A (ja) * 2012-11-30 2015-12-24 ノボザイムス,インコーポレイティド 組換え酵母による3−ヒドロキシプロピオン酸の生産
WO2014160050A1 (en) * 2013-03-14 2014-10-02 Butamax Advanced Biofuels Llc Glycerol 3- phosphate dehydrogenase for butanol production
JP2016518821A (ja) 2013-03-15 2016-06-30 カーギル・インコーポレイテッド 3−ヒドロキシプロピオン酸の回収
US9447438B2 (en) 2013-03-15 2016-09-20 Cargill, Incorporated Acetyl-coA carboxylases
US20150044746A1 (en) * 2013-03-15 2015-02-12 Opx Biotechnologies, Inc. Method of enhanced bioproduction
EP3008178A1 (en) 2013-06-14 2016-04-20 Technical University of Denmark Microbial production of 3-hydroxypropionic acid
EP3008179A1 (en) 2013-06-14 2016-04-20 Technical University of Denmark 3hp tolerance
WO2015010103A2 (en) 2013-07-19 2015-01-22 Opx Biotechnologies, Inc. Microorganisms and methods for the production of fatty acids and fatty acid derived products
US11408013B2 (en) 2013-07-19 2022-08-09 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
US9556443B2 (en) 2013-07-19 2017-01-31 Samsung Electronics Co., Ltd. Yeast cell with inactivated NADH dehydrogenase and method of producing lactate using the yeast cell
US9845484B2 (en) 2013-07-31 2017-12-19 Novozymes A/S 3-hydroxypropionic acid production by recombinant yeasts expressing an insect aspartate 1-decarboxylase
WO2015031504A1 (en) * 2013-08-27 2015-03-05 The Regents Of The University Of California RECOMBINANT PATHWAY AND ORGANISMS FOR MALONYL-CoA SYNTHESIS
WO2015036278A1 (de) 2013-09-12 2015-03-19 Basf Se Verfahren zur dehydratisierung von 3-hydroxypropionsäure zu acrylsäure
WO2015036273A1 (de) 2013-09-12 2015-03-19 Basf Se Verfahren zur herstellung von acrylsäure
US10252970B2 (en) 2013-09-12 2019-04-09 Basf Se Method of dehydrating 3-hydroxypropionic acid to form acrylic acid
JP6499587B2 (ja) 2013-11-22 2019-04-10 Jmtcエンザイム株式会社 形質転換体およびその製造方法、ならびに乳酸の製造方法
JP6488666B2 (ja) * 2013-11-22 2019-03-27 Agc株式会社 クローニングベクター、発現ベクターおよび形質転換体の製造方法
KR101555867B1 (ko) 2014-04-18 2015-10-01 부산대학교 산학협력단 3-하이드록시프로피온산을 분해하지 않는 슈도모나스 데니트리피칸스 결실 변이균주 및 이를 이용한 3-하이드록시프로피온산의 생산방법
WO2015200545A1 (en) * 2014-06-26 2015-12-30 Lygos, Inc. Recombinant host cells for the production of malonate
WO2016026763A1 (en) 2014-08-18 2016-02-25 Basf Se Process for preparing acrylic acid using a heterogeneous alumina catalyst
JP6786477B2 (ja) 2014-08-29 2020-11-18 エスケー イノベーション カンパニー リミテッドSk Innovation Co.,Ltd. 3−hpを生産することができる組換え酵母およびこれを利用した3−hpの製造方法
EP2993228B1 (en) 2014-09-02 2019-10-09 Cargill, Incorporated Production of fatty acid esters
US10214754B2 (en) 2014-10-10 2019-02-26 Jmtc Enzyme Corporation Transformant and its production process, and method for producing lactic acid
US20170362613A1 (en) * 2014-12-19 2017-12-21 Novozymes A/S Recombinant Host Cells For The Production Of 3-Hydroxypropionic Acid
US20180273915A1 (en) * 2014-12-19 2018-09-27 Novozymes A/S Recombinant Host Cells For The Production Of 3-Hydroxypropionic Acid
WO2016135020A1 (de) 2015-02-24 2016-09-01 Basf Se Verfahren zur kontinuierlichen dehydratisierung von 3-hydroxypropionsäure zu acrylsäure
WO2016138303A1 (en) 2015-02-27 2016-09-01 Novozymes A/S Mutant host cells for the production of 3-hydroxypropionic acid
WO2016162175A1 (de) 2015-04-07 2016-10-13 Basf Se Verfahren zur dehydratisierung von 3-hydroxypropionsäure zu acrylsäure
WO2016200239A1 (ko) * 2015-06-11 2016-12-15 부산대학교 산학협력단 3-하이드록시프로피온산에 의해 발현이 유도되는 프로모터 시스템 및 이를 이용한 3-하이드록시프로피온산의 생물학적 생산방법
EP3321364B1 (en) 2015-06-11 2022-12-28 Noroo IC Co., Ltd. Promoter system inducing expression by 3-hydroxypropionic acid and method for biological production of 3-hydroxypropionic acid using same
EP3325608B1 (en) * 2015-07-21 2021-11-24 The Governing Council of the University of Toronto Methods and microorganisms for the production of 1,3-butanediol
WO2017035270A1 (en) 2015-08-24 2017-03-02 Novozymes A/S Beta-alanine aminotransferases for the production of 3-hydroxypropionic acid
WO2017083683A1 (en) * 2015-11-12 2017-05-18 Lygos, Inc. Recombinant host cells and methods for the anaerobic production of l-aspartate and beta-alanine
US20180258437A1 (en) * 2015-11-12 2018-09-13 Lygos, Inc. Recombinant host cells and methods for the production of l-aspartate and beta-alanine
DE102016114555A1 (de) 2016-08-05 2018-02-08 Thyssenkrupp Ag Prozess zur Herstellung von Acrylsäure aus einer wässrigen 3-Hydroxypropanol-Lösung
US20190345522A1 (en) 2016-12-06 2019-11-14 Novozymes A/S Improved Processes For Production Of Ethanol From Xylose-Containing Cellulosic Substrates Using Engineered Yeast Strains
CN110494566A (zh) 2017-02-02 2019-11-22 嘉吉公司 产生c6-c10脂肪酸衍生物的经遗传修饰的细胞
US11091753B2 (en) 2017-05-31 2021-08-17 Novozymes A/S Xylose fermenting yeast strains and processes thereof for ethanol production
CA3064042A1 (en) 2017-06-02 2018-12-06 Novozymes A/S Improved yeast for ethanol production
CN110997619B (zh) 2017-08-17 2023-06-27 巴斯夫欧洲公司 连续制备丙烯酸正丁酯或丙烯酸异丁酯的方法
US11834484B2 (en) 2017-08-29 2023-12-05 Novozymes A/S Bakers's yeast expressing anti-staling/freshness amylases
AU2019213033A1 (en) 2018-01-29 2020-09-17 Microbiogen Pty. Ltd. Microorganisms with improved nitrogen utilization for ethanol production
KR102419608B1 (ko) * 2018-02-08 2022-07-08 주식회사 엘지화학 고농도 3-하이드록시프로피온산 수용액의 제조 방법
BR112020024347A2 (pt) 2018-05-31 2021-02-23 Novozymes A/S processos para aumentar o crescimento e a produtividade de levedura
CA3143683A1 (en) * 2018-06-25 2020-01-02 Lygos, Inc. Recombinant host cells and methods for the production of aspartic acid and s-alanine
BR112021001282A2 (pt) 2018-07-25 2021-04-27 Novozymes A/S levedura expressando enzimas para produção de etanol
CA3114783A1 (en) 2018-10-08 2020-04-16 Novozymes A/S Enzyme-expressing yeast for ethanol production
JP7370587B2 (ja) * 2018-10-30 2023-10-30 GreenEarthInstitute株式会社 有機化合物の製造方法およびコリネ型細菌
EP3877525A2 (en) 2018-12-18 2021-09-15 Braskem S.A. Co-production pathway for 3-hp and acetyl-coa derivatives from malonate semialdehyde
CN109852605A (zh) * 2019-01-16 2019-06-07 徐州工程学院 一种诱变筛选高产3-羟基丙酸菌株的方法
CA3143381A1 (en) 2019-07-26 2021-02-04 Novozymes A/S Microorganisms with improved nitrogen transport for ethanol production
CN112390855B (zh) * 2019-07-31 2022-04-29 上海交通大学医学院附属仁济医院 Pretide-146a在制备缓解或治疗自身免疫性疾病的药物中的应用
MX2022000831A (es) 2019-08-05 2022-02-10 Novozymes As Mezclas de enzimas y procesos para producir un ingrediente alimenticio de alto contenido proteico a partir de un subproducto de la vinaza entera.
BR112021026477A2 (pt) 2019-08-06 2022-02-08 Novozymes As Célula hospedeira recombinante, métodos de produção de um produto de fermentação a partir de um material contendo amido ou contendo celulose, de produção do polipeptídeo maduro, de produção de um derivado de uma célula hospedeira recombinante e de produção de etanol, construto de ácido nucleico ou vetor de expressão, composição, e, uso de uma célula hospedeira recombinante
MX2022002834A (es) 2019-09-16 2022-04-06 Novozymes As Polipeptidos con actividad beta-glucanasa y polinucleotidos que los codifican.
EP4073089A1 (en) 2019-12-10 2022-10-19 Novozymes A/S Microorganism for improved pentose fermentation
EP4103709A2 (en) 2020-02-10 2022-12-21 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
CA3188324A1 (en) 2020-06-29 2022-01-06 Basf Se Device for carrying out material exchange processes
EP4190907A4 (en) * 2020-07-31 2023-12-06 LG Chem, Ltd. PROCESS FOR PREPARING 3-HYDROXYPROPIONIC ACID IN TWO STEP
CN111985041B (zh) * 2020-09-17 2021-03-30 青岛理工大学 一种加固边坡挡墙高度确定方法及加固边坡挡墙
EP4222167A1 (en) 2020-09-30 2023-08-09 Nobell Foods, Inc. Recombinant milk proteins and food compositions comprising the same
KR20230076829A (ko) * 2020-09-30 2023-05-31 게노미엄, 아이엔씨. 바이오아크롤레인 및 바이오아크릴산을 생산하는 발효 공정
US10894812B1 (en) 2020-09-30 2021-01-19 Alpine Roads, Inc. Recombinant milk proteins
US10947552B1 (en) 2020-09-30 2021-03-16 Alpine Roads, Inc. Recombinant fusion proteins for producing milk proteins in plants
EP4237555A1 (en) 2020-11-02 2023-09-06 Novozymes A/S Glucoamylase variants and polynucleotides encoding same
WO2022098162A1 (ko) * 2020-11-05 2022-05-12 주식회사 엘지화학 3-하이드록시프로피온산의 생산 방법
CN116323929A (zh) * 2020-11-05 2023-06-23 株式会社Lg化学 具有从葡萄糖生产3-羟基丙酸能力的微生物及其用途
AU2022218205A1 (en) 2021-02-08 2023-05-25 Lanzatech, Inc. Recombinant microorganisms and uses therefor
AU2022288057A1 (en) 2021-06-07 2023-12-21 Novozymes A/S Engineered microorganism for improved ethanol fermentation
FR3125042B1 (fr) 2021-07-09 2024-04-12 Snf Sa Procédé d’obtention d’alkyl(méth)acrylamide substitué biosourcé
FR3125048B1 (fr) 2021-07-09 2024-04-19 Snf Sa Polymère biosourcé à biodégradabilité améliorée
FR3125040B1 (fr) 2021-07-09 2024-04-26 Snf Sa Procédé d’obtention de bio-monomère à partir de diméthylaminoethanol d’origine renouvelable
WO2023168244A1 (en) 2022-03-03 2023-09-07 Cargill, Incorporated Genetically modified yeast and fermentation processes for the production of 3-hydroxypropionate
WO2023168233A1 (en) 2022-03-03 2023-09-07 Cargill, Incorporated Genetically modified yeast and fermentation processes for the production of 3-hydroxypropionate
CN115595328A (zh) * 2022-03-07 2023-01-13 中国科学院微生物研究所(Cn) 天冬氨酸脱羧酶在发酵生产维生素b5中的应用
CN116024184B (zh) * 2022-07-26 2024-03-15 南京科技职业学院 醛脱氢酶突变体及其在制备5-羟甲基-2-呋喃甲酸中的应用
EP4638768A2 (en) 2022-12-19 2025-10-29 Novozymes A/S Processes for producing fermentation products using fiber-degrading enzymes with engineered yeast
WO2024226289A1 (en) 2023-04-26 2024-10-31 Cargill, Incorporated Methods for producing propionic acid
WO2024258820A2 (en) 2023-06-13 2024-12-19 Novozymes A/S Processes for producing fermentation products using engineered yeast expressing a beta-xylosidase
WO2025058922A1 (en) 2023-09-15 2025-03-20 Cargill, Incorporated Rising film evaporator clean-in-place method and system
WO2025165198A1 (ko) * 2024-01-31 2025-08-07 주식회사 엘지화학 3-하이드록시프로피온산의 생산 방법

Family Cites Families (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL39710A (en) 1972-06-19 1975-04-25 Imi Inst For Res & Dev Recovery of acids from aqueous solutions by solvent extraction
US4771001A (en) 1986-03-27 1988-09-13 Neurex Corp. Production of lactic acid by continuous fermentation using an inexpensive raw material and a simplified method of lactic acid purification
US5210296A (en) 1990-11-19 1993-05-11 E. I. Du Pont De Nemours And Company Recovery of lactate esters and lactic acid from fermentation broth
US5132456A (en) 1991-05-07 1992-07-21 The Regents Of The University Of California Sorption of carboxylic acid from carboxylic salt solutions at PHS close to or above the pKa of the acid, with regeneration with an aqueous solution of ammonia or low-molecular-weight alkylamine
US5420304A (en) 1992-03-19 1995-05-30 Biopak Technology, Ltd. Method to produce cyclic esters
AT398982B (de) 1993-02-18 1995-02-27 Vogelbusch Gmbh Verfahren zur abtrennung und reinigung von milchsäure
US5510526A (en) 1993-06-29 1996-04-23 Cargill, Incorporated Lactic acid production, separation and/or recovery process
IL109003A (en) 1994-03-16 1999-09-22 Yissum Res Dev Co Process and extractant composition for extracting water-soluble carboxylic and mineral acids
IT1294728B1 (it) 1997-09-12 1999-04-12 Biopolo S C A R L Ceppi di lievito per la riproduzione di acido lattico
WO1999053035A1 (en) 1998-04-13 1999-10-21 The University Of Georgia Research Foundation, Inc. Pyruvate carboxylase overexpression for enhanced production of oxaloacetate-derived biochemicals in microbial cells
DE69938105T2 (de) * 1998-08-04 2009-01-29 Metabolix, Inc., Cambridge Herstellung von polyhydroxyalkanoaten aus polyolen
CA2374482C (en) 1999-05-21 2012-09-18 Cargill Dow Llc Methods and materials for the synthesis of organic products
WO2001016346A1 (en) 1999-08-30 2001-03-08 Wisconsin Alumni Research Foundation Production of 3-hydroxypropionic acid in recombinant organisms
US6852517B1 (en) 1999-08-30 2005-02-08 Wisconsin Alumni Research Foundation Production of 3-hydroxypropionic acid in recombinant organisms
JP4098455B2 (ja) 2000-03-10 2008-06-11 株式会社日立製作所 マーク画像中の電子透かし情報の参照方法及び計算機
JP4490628B2 (ja) 2000-11-20 2010-06-30 カーギル インコーポレイテッド 3−ヒドロキシプロピオン酸および他の有機化合物
US7109010B2 (en) 2000-11-22 2006-09-19 Nature Works Llc Methods and materials for the synthesis of organic products
CA2474152A1 (en) 2001-11-23 2003-06-19 Cargill Dow Llc Methods and materials for the production of organic products in cells of candida species
DE60327804D1 (de) 2002-01-18 2009-07-09 Novozymes As Alanin-2,3-aminomutase
JP2005521718A (ja) 2002-03-25 2005-07-21 カーギル,インコーポレイティド β−ヒドロキシカルボン酸の誘導体の製造方法
WO2003102200A2 (en) 2002-05-30 2003-12-11 Cargill Dow Llc Fermentation process using specific oxygen uptake rates as a process control
US7126034B2 (en) 2002-11-01 2006-10-24 Cargill, Incorporated Process for preparation of 1,3-propanediol
CA2516913A1 (en) 2003-02-24 2004-09-10 Cargill, Incorporated Process for preparing 3-hydroxycarboxylic acids
BRPI0411925A (pt) 2003-06-26 2006-08-15 Cargill Inc processo para separação e recuperação de ácido 3-hidroxipropiÈnico e ácido acrìlico
CN100422131C (zh) 2003-06-26 2008-10-01 嘉吉有限公司 分离和回收3-羟基丙酸和丙烯酸的方法
US7326557B2 (en) 2003-11-14 2008-02-05 Rice University Increasing intracellular NADPH availability in E. coli
DK1706457T3 (da) 2003-12-04 2012-05-21 Novozymes As Fremstilling af 3-hydroxypropionsyre ved anvendelse af beta-alanin/pyruvataminotransferase
WO2006022664A2 (en) 2004-07-30 2006-03-02 Cargill Incorporated Alanine 2, 3 aminomutases
US7987056B2 (en) 2004-09-20 2011-07-26 The Regents Of The University Of Colorado, A Body Corporate Mixed-library parallel gene mapping quantitative micro-array technique for genome-wide identification of trait conferring genes
MX2007004980A (es) 2004-10-25 2007-06-14 Codexis Inc Alanina 2,3-aminomutasas mejoradas, y polinucleotidos relacionados.
DK1760156T3 (da) 2005-08-10 2013-03-18 Univ Florida Materialer og fremgangsmåder til effektiv mælkesyrefremstilling
US7846688B2 (en) 2005-08-15 2010-12-07 The Regents Of The University Of Colorado Broad host range vectors for shotgun and expression library cloning in Gram negative bacteria
DE102005048818A1 (de) 2005-10-10 2007-04-12 Degussa Ag Mikrobiologische Herstellung von 3-Hydroxypropionsäure
EP2001992B1 (en) 2006-03-13 2016-07-20 Cargill Inc. Yeast cells having disrupted pathway from dihydroxyacetone phosphate to glycerol
WO2007130745A1 (en) 2006-03-15 2007-11-15 Regents Of The University Of Colorado Enhanced alcohol tolerant microorganism and methods of use thereof
US20080103060A1 (en) 2006-08-08 2008-05-01 Regents Of The University Of Colorado Compositions and methods for chemical reporter vectors
BRPI0716212A2 (pt) * 2006-08-30 2013-10-15 Cargill Inc Beta-alanina/alfa-cetoglutarato aminotransferase para produção de ácido 3-hidroxipropiônico
US8938765B2 (en) 2006-12-22 2015-01-20 Time Warner Cable Enterprises Llc Methods, apparatus and user interface for providing content on demand
AU2008206403A1 (en) 2007-01-12 2008-07-24 The Regents Of The University Of Colorado, A Body Corporate Compositions and methods for enhancing tolerance for the production of organic chemicals produced by microorganisms
US8673601B2 (en) 2007-01-22 2014-03-18 Genomatica, Inc. Methods and organisms for growth-coupled production of 3-hydroxypropionic acid
US8048624B1 (en) 2007-12-04 2011-11-01 Opx Biotechnologies, Inc. Compositions and methods for 3-hydroxypropionate bio-production from biomass
BRPI0821230A2 (pt) 2007-12-19 2019-09-24 Novozymes As "constructo de ácido nucleico, cédula microbiana hospedeira recombinante, métodos para priduzir um polipeptídeo tendo atividade intensificadora celulolítica, para produzir um mutante de uma cédula precursora, para inibir a expressão de um polipeptídeo com atividade de intensificação celulolítica em uma célula, para produzir uma proteína, para degradar ou converter um material celulósico, e, para fermentar um material celulósico"
WO2009089457A1 (en) 2008-01-11 2009-07-16 Novozymes A/S Methods for producing 3-hydroxypropionic acid and compounds thereof
EP2313491A4 (en) 2008-07-08 2011-12-07 Opx Biotechnologies Inc METHODS, COMPOSITIONS AND SYSTEMS FOR BIOSYNTHETIC BIOPRODUCTION OF 1,4-BUTANEDIOL
US20100021978A1 (en) * 2008-07-23 2010-01-28 Genomatica, Inc. Methods and organisms for production of 3-hydroxypropionic acid
US20110244575A1 (en) * 2008-07-23 2011-10-06 Lipscomb Tanya E W Methods, systems and compositions for increased microorganism tolerance to and production of 3-hydroxypropionic acid (3-hp)
US20110281314A1 (en) 2008-08-04 2011-11-17 Lynch Michael D Methods, systems and compositions related to microbial bio-production of butanol and/or isobutanol
EP2326709A4 (en) * 2008-09-15 2013-01-23 Opx Biotechnologies Inc METHODS, SYSTEMS AND COMPOSITIONS RELATED TO REDUCED MICROBIAL PRODUCTION OF 3-HYDROXYPROPIONIC ACID (3-HP) IN ALDEHYDMETABOLITE
US8518684B2 (en) 2008-11-18 2013-08-27 Novozymes, Inc. Methods and compositions for degrading cellulosic material
US20110144377A1 (en) 2009-06-16 2011-06-16 E. I. Du Pont Nemours And Company Process for the biological production of 3-hydroxypropionic acid with high yield
WO2011038364A1 (en) 2009-09-27 2011-03-31 Opx Biotechnologies, Inc. Method for producing 3-hydroxypropionic acid and other products
US8809027B1 (en) 2009-09-27 2014-08-19 Opx Biotechnologies, Inc. Genetically modified organisms for increased microbial production of 3-hydroxypropionic acid involving an oxaloacetate alpha-decarboxylase
EP2491122A1 (en) 2009-10-23 2012-08-29 Novozymes Inc. Cellobiohydrolase variants and polynucleotides encoding same
BR112012006847A2 (pt) 2009-10-29 2015-09-08 Novozymes As polipeptídeo polinucleotídeo, célula hospedeira recombinante, métodos para produzir o polipeptídeo para produzir um mutante de uma célula parental, para inibir a expressão de um polipeptídeo, para produzir uma proteína, para degradar ou converter um material celulósico, para produzir um produto de fermentação, para produzir um produto de fermentação e pra fermentar um material celulósico, planta transgênica, parte da planta ou célula da planta, molécula de rna inibitória de filamento duplo, e, composição.
WO2011063363A2 (en) 2009-11-20 2011-05-26 Opx Biotechnologies, Inc. Production of an organic acid and/or related chemicals
CA2788045A1 (en) 2010-01-27 2011-08-04 Opx Biotechnologies, Inc. Microorganism production of high-valve chemical products, and related compositions, methods and systems
US20130052702A1 (en) 2010-03-30 2013-02-28 Novozymes North America, Inc. Methods for Enhancing By-Products From Fermentation Processes
MX2013001540A (es) 2010-08-12 2013-04-24 Novozymes Inc Composiciones que comprende un polipeptido que tiene actividad de incremento celulolititico y un compuesto de quinona, y uso de las mismas.
MX2013005654A (es) * 2010-11-22 2013-07-17 Novozymes Inc Composiciones y metodos para la produccion de acido 3-hidroxipropionico.
US20140121118A1 (en) 2010-11-23 2014-05-01 Opx Biotechnologies, Inc. Methods, systems and compositions regarding multiplex construction protein amino-acid substitutions and identification of sequence-activity relationships, to provide gene replacement such as with tagged mutant genes, such as via efficient homologous recombination
EP2864282A4 (en) 2012-06-20 2016-01-20 Opx Biotechnologies Inc CLEANING OF 3-HYDROXYPROPIONIC ACID FROM RAW CELLBOUILLON AND DEHYDRATION TO ACRYLIC ACID
US20130345470A1 (en) 2012-06-20 2013-12-26 Opx Biotechnologies, Inc. Purification of 3-Hydroxypropionic Acid from Crude Cell Broth and Production of Acrylamide
JP2016518821A (ja) 2013-03-15 2016-06-30 カーギル・インコーポレイテッド 3−ヒドロキシプロピオン酸の回収
US9447438B2 (en) 2013-03-15 2016-09-20 Cargill, Incorporated Acetyl-coA carboxylases
WO2014145343A1 (en) 2013-03-15 2014-09-18 Opx Biotechnologies, Inc. Bioproduction of chemicals
US20150044746A1 (en) 2013-03-15 2015-02-12 Opx Biotechnologies, Inc. Method of enhanced bioproduction
EP2976141A4 (en) 2013-03-15 2016-10-05 Cargill Inc FLASHING FOR PRODUCTION CLEANING AND RECOVERY

Similar Documents

Publication Publication Date Title
JP2013542747A5 (enExample)
JP5772594B2 (ja) 形質転換体およびその製造方法、ならびに乳酸の製造方法
CN102016024B (zh) 突变体酵母及使用其的物质生产方法
MY169074A (en) Yeast strains engineered to produce ethanol from acetic acid and glycerol
CN112725210B (zh) 抑制乳酸代谢和乙醇产生的重组耐酸酵母及使用其生产乳酸的方法
JP2013528398A5 (enExample)
BR112013010169B1 (pt) Microrganismo monascus ruber, seu uso na produção de ácido láctico e método para produzir uma composição a um rendimento elevado, que compreende um ácido láctico
EP3380626A1 (en) Genetically modified yeasts and fermentation processes using genetically modified yeasts
CN106086058A (zh) 一种减少蛹虫草出菇时间及提高出菇产量的方法
CN108603186B (zh) 共表达外源糖化酶的酵母菌株、获得所述酵母菌株的方法及其用于生产生物乙醇的用途
JP5813977B2 (ja) Kluyveromyces属の変異体酵母及びこれを用いたエタノールの製造方法
CN107937297B (zh) 一株多抑制物胁迫耐受性酿酒酵母及制备方法、应用
CN104450804A (zh) 一种削弱丙酮酸分解代谢强化丙酮酸积累的方法
CN107974453A (zh) 一种提高酿酒酵母细胞活力及多重抗逆性的方法和应用
CN104911118A (zh) 一种乳酸脱氢酶人源化酿酒酵母及其构建方法
CN103710274B (zh) 一种胞外丙酮酸产量提高的基因工程菌及其应用
CN103131718B (zh) 来源产甘油假丝酵母新型耐高渗功能基因CgHog1的克隆及其应用
CN102226154B (zh) 具有双重筛选标记的多形汉逊酵母菌及其应用
CN109266566A (zh) 一种调节光滑球拟酵母渗透压胁迫的方法
CN102120966A (zh) Ura3缺陷型毕赤酵母x-33菌株的构建及应用
CN107723302B (zh) 一种过表达产甘油假丝酵母CgGAD1提高渗透压耐受性的方法
CN108949664B (zh) 一种酸胁迫抗性提高的乳酸菌工程菌及其应用
CN104845948B (zh) 一种酶活性提高的丙酮酸羧化酶突变体p474n及其应用
CN105132388A (zh) 一种酶活性提高的丙酮酸羧化酶突变体r485p及其应用
CN103923847A (zh) 一种强化前体供应增强α-酮戊二酸合成的解脂亚洛酵母