JP2013528398A5 - - Google Patents
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- Publication number
- JP2013528398A5 JP2013528398A5 JP2013515512A JP2013515512A JP2013528398A5 JP 2013528398 A5 JP2013528398 A5 JP 2013528398A5 JP 2013515512 A JP2013515512 A JP 2013515512A JP 2013515512 A JP2013515512 A JP 2013515512A JP 2013528398 A5 JP2013528398 A5 JP 2013528398A5
- Authority
- JP
- Japan
- Prior art keywords
- butanol
- culture
- production
- yeast
- gram
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 claims 54
- 238000004519 manufacturing process Methods 0.000 claims 29
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims 17
- ZXEKIIBDNHEJCQ-UHFFFAOYSA-N isobutanol Chemical compound CC(C)CO ZXEKIIBDNHEJCQ-UHFFFAOYSA-N 0.000 claims 10
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 9
- 239000008103 glucose Substances 0.000 claims 9
- 230000037361 pathway Effects 0.000 claims 9
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 8
- 229910052799 carbon Inorganic materials 0.000 claims 8
- 239000000758 substrate Substances 0.000 claims 8
- 241000235013 Yarrowia Species 0.000 claims 4
- 230000001580 bacterial effect Effects 0.000 claims 4
- 238000000855 fermentation Methods 0.000 claims 4
- 230000004151 fermentation Effects 0.000 claims 4
- BTANRVKWQNVYAZ-UHFFFAOYSA-N butan-2-ol Chemical compound CCC(C)O BTANRVKWQNVYAZ-UHFFFAOYSA-N 0.000 claims 3
- 239000002028 Biomass Substances 0.000 claims 2
- 241000222120 Candida <Saccharomycetales> Species 0.000 claims 2
- 241000235648 Pichia Species 0.000 claims 2
- 241000235070 Saccharomyces Species 0.000 claims 2
- 241000235346 Schizosaccharomyces Species 0.000 claims 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 2
- 238000000622 liquid--liquid extraction Methods 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 229910052760 oxygen Inorganic materials 0.000 claims 2
- 239000001301 oxygen Substances 0.000 claims 2
- 238000000638 solvent extraction Methods 0.000 claims 2
- 230000006696 biosynthetic metabolic pathway Effects 0.000 claims 1
- 238000012262 fermentative production Methods 0.000 claims 1
- 238000002703 mutagenesis Methods 0.000 claims 1
- 231100000350 mutagenesis Toxicity 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35573310P | 2010-06-17 | 2010-06-17 | |
| US61/355,733 | 2010-06-17 | ||
| PCT/US2011/040697 WO2011159894A1 (en) | 2010-06-17 | 2011-06-16 | Yeast production culture for the production of butanol |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013528398A JP2013528398A (ja) | 2013-07-11 |
| JP2013528398A5 true JP2013528398A5 (enExample) | 2014-07-03 |
Family
ID=44627329
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013515512A Abandoned JP2013528398A (ja) | 2010-06-17 | 2011-06-16 | ブタノール産生用の酵母生産培養物 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20120149080A1 (enExample) |
| EP (1) | EP2582786A1 (enExample) |
| JP (1) | JP2013528398A (enExample) |
| KR (1) | KR20130027551A (enExample) |
| CN (1) | CN103201376A (enExample) |
| AU (1) | AU2011268326B2 (enExample) |
| BR (1) | BR112012031847A2 (enExample) |
| CA (1) | CA2801576A1 (enExample) |
| MX (1) | MX2012014550A (enExample) |
| NZ (1) | NZ603546A (enExample) |
| WO (1) | WO2011159894A1 (enExample) |
| ZA (1) | ZA201208575B (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8945899B2 (en) | 2007-12-20 | 2015-02-03 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase using NADH |
| KR101573775B1 (ko) | 2007-04-18 | 2015-12-04 | 부타맥스 어드밴스드 바이오퓨얼스 엘엘씨 | 고도 활성 케톨-산 리덕토아이소머라아제 효소를 이용한 아이소부탄올의 발효 생산 |
| US8188250B2 (en) * | 2008-04-28 | 2012-05-29 | Butamax(Tm) Advanced Biofuels Llc | Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans |
| KR20110063576A (ko) | 2008-09-29 | 2011-06-10 | 부타맥스 어드밴스드 바이오퓨얼스 엘엘씨 | 효모에서 증가된 이종성 Fe-S 효소 활성 |
| CN102762722B (zh) | 2009-12-29 | 2015-05-20 | 布特马斯先进生物燃料有限责任公司 | 用于发酵生产低级烷基醇的醇脱氢酶(adh) |
| US9297016B2 (en) | 2010-02-17 | 2016-03-29 | Butamax Advanced Biofuels Llc | Activity of Fe—S cluster requiring proteins |
| EP3269806B1 (en) | 2010-09-07 | 2020-05-27 | Butamax (TM) Advanced Biofuels LLC | Integration of a polynucleotide encoding a polypeptide that catalyzes pyruvate to acetolactate conversion |
| CA2830215C (en) | 2011-03-14 | 2018-07-10 | Easel Biotechnologies, Llc | Microbial synthesis of aldehydes and corresponding alcohols |
| CA2831130C (en) | 2011-03-24 | 2021-10-26 | Butamax (Tm) Advanced Biofuels Llc | Host cells and methods for production of isobutanol |
| JP6093764B2 (ja) | 2011-07-28 | 2017-03-08 | ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー | ケトイソ吉草酸デカルボキシラーゼ酵素およびその使用方法 |
| KR20170096226A (ko) | 2011-11-03 | 2017-08-23 | 이젤 바이오테크날러지스, 엘엘씨 | 미생물에 의한 n-부티르알데하이드의 생성 |
| WO2013086222A2 (en) | 2011-12-09 | 2013-06-13 | Butamax(Tm) Advanced Biofuels Llc | Process to remove product alcohols from fermentation broth |
| AU2012362144A1 (en) | 2011-12-30 | 2014-07-03 | Butamax (Tm) Advanced Biofuels Llc | Genetic switches for butanol production |
| CA2861613A1 (en) | 2011-12-30 | 2013-07-04 | Butamax Advanced Biofuels Llc | Fermentative production of alcohols |
| CN104284981A (zh) | 2012-03-23 | 2015-01-14 | 布特马斯先进生物燃料有限责任公司 | 在针对产丁醇生物的培养基中补充乙酸盐 |
| WO2013176909A2 (en) | 2012-05-11 | 2013-11-28 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase enzymes and methods of use |
| BR112015003701A2 (pt) | 2012-08-22 | 2017-12-12 | Butamax Advanced Biofuels Llc | células hospedeiras recombinantes, método para aprimoramento, processo para a produção de um álcool, polinucleotídeo isolado, cassete de expressão e composição |
| US9840724B2 (en) | 2012-09-21 | 2017-12-12 | Butamax Advanced Biofuels Llc | Production of renewable hydrocarbon compositions |
| US9512408B2 (en) | 2012-09-26 | 2016-12-06 | Butamax Advanced Biofuels Llc | Polypeptides with ketol-acid reductoisomerase activity |
| US9273330B2 (en) | 2012-10-03 | 2016-03-01 | Butamax Advanced Biofuels Llc | Butanol tolerance in microorganisms |
| WO2014106107A2 (en) | 2012-12-28 | 2014-07-03 | Butamax (Tm) Advanced Biofuels Llc | Dhad variants for butanol production |
| WO2014160050A1 (en) | 2013-03-14 | 2014-10-02 | Butamax Advanced Biofuels Llc | Glycerol 3- phosphate dehydrogenase for butanol production |
| US9034631B2 (en) * | 2013-03-14 | 2015-05-19 | Poet Research, Inc. | Systems and methods for yeast propagation |
| WO2014151190A1 (en) | 2013-03-15 | 2014-09-25 | Butamax Advanced Biofuels Llc | Dhad variants and methods of screening |
| US9771602B2 (en) | 2013-03-15 | 2017-09-26 | Butamax Advanced Biofuels Llc | Competitive growth and/or production advantage for butanologen microorganism |
| WO2015002913A1 (en) * | 2013-07-03 | 2015-01-08 | Butamax Advanced Biofuels Llc | Partial adaptation for butanol production |
| CA2957920A1 (en) | 2014-08-11 | 2016-02-18 | Butamax Advanced Biofuels Llc | Yeast preparations and methods of making the same |
| US20180016543A1 (en) * | 2015-02-10 | 2018-01-18 | Erbslöh Geisenheim AG | Method of producing yeast mutants and the use thereof |
| CA3021033A1 (en) | 2016-05-05 | 2017-11-09 | Newpek S.A. De C.V. | Enzymatic methods for butanol production |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4284724A (en) | 1977-08-25 | 1981-08-18 | Hideki Fukuda | Method of highly concentrated cultivation of yeasts |
| US4414329A (en) | 1980-01-15 | 1983-11-08 | Phillips Petroleum Company | Biochemical conversions by yeast fermentation at high cell densities |
| US4765992A (en) | 1984-06-01 | 1988-08-23 | Universite De Bordeaux Ii | Stimulation of alcoholic fermentation by adsorption of toxic substances with cell walls |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US9297028B2 (en) | 2005-09-29 | 2016-03-29 | Butamax Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
| NZ566406A (en) | 2005-10-26 | 2012-04-27 | Butamax Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
| US8945899B2 (en) | 2007-12-20 | 2015-02-03 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase using NADH |
| US8828704B2 (en) | 2006-05-02 | 2014-09-09 | Butamax Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
| US8206970B2 (en) | 2006-05-02 | 2012-06-26 | Butamax(Tm) Advanced Biofuels Llc | Production of 2-butanol and 2-butanone employing aminobutanol phosphate phospholyase |
| KR101573775B1 (ko) | 2007-04-18 | 2015-12-04 | 부타맥스 어드밴스드 바이오퓨얼스 엘엘씨 | 고도 활성 케톨-산 리덕토아이소머라아제 효소를 이용한 아이소부탄올의 발효 생산 |
| US20090139134A1 (en) | 2007-10-04 | 2009-06-04 | Bio Architecture Lab, Inc. | Biofuel production |
| CA2703191A1 (en) * | 2007-10-26 | 2009-04-30 | Arbor Fuel Inc. | Methods for the production of n-butanol |
| EP2677028B1 (en) | 2007-12-20 | 2016-03-09 | Butamax (TM) Advanced Biofuels LLC | Ketol-acid reductoisomerase using NADH |
| JP2011514140A (ja) | 2007-12-27 | 2011-05-06 | ジーヴォ,インコーポレイテッド | 低濃度水溶液からの高級アルコールの回収 |
| US8188250B2 (en) | 2008-04-28 | 2012-05-29 | Butamax(Tm) Advanced Biofuels Llc | Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans |
| NZ588988A (en) * | 2008-06-04 | 2012-08-31 | Butamax Tm Advanced Biofuels | A method for producing butanol using two-phase extractive fermentation |
| BRPI0909989A2 (pt) | 2008-06-05 | 2021-06-22 | Butamax Advanced Biofuels Llc | célula de levedura recombinante e método para a produção de um produto |
| MX2011003238A (es) | 2008-09-29 | 2011-04-28 | Butamax Tm Advanced Biofuels | Identificacion y uso de dihidroxiacido deshidratasas [2fe-2s] bacterianas. |
| BRPI0914521A2 (pt) | 2008-10-27 | 2016-07-26 | Butamax Advanced Biofuels Llc | célula hospedeira microbiana recombinante, método de aumento da produção de isobutanol e método de produção de isobutanol |
| KR20120104509A (ko) | 2009-06-26 | 2012-09-21 | 게보 인코포레이티드 | 묽은 수용액으로부터 고급 알코올들의 회수 |
| WO2011041426A1 (en) | 2009-09-29 | 2011-04-07 | Butamax(Tm) Advanced Biofuels Llc | Improved yeast production host cells |
| US20110244536A1 (en) | 2009-09-29 | 2011-10-06 | Butamax(Tm) Advanced Biofuels Llc | Fermentive production of isobutanol using highly effective ketol-acid reductoisomerase enzymes |
-
2011
- 2011-06-16 BR BR112012031847A patent/BR112012031847A2/pt not_active Application Discontinuation
- 2011-06-16 WO PCT/US2011/040697 patent/WO2011159894A1/en not_active Ceased
- 2011-06-16 JP JP2013515512A patent/JP2013528398A/ja not_active Abandoned
- 2011-06-16 CN CN2011800298462A patent/CN103201376A/zh active Pending
- 2011-06-16 US US13/162,165 patent/US20120149080A1/en not_active Abandoned
- 2011-06-16 AU AU2011268326A patent/AU2011268326B2/en not_active Ceased
- 2011-06-16 CA CA2801576A patent/CA2801576A1/en not_active Abandoned
- 2011-06-16 KR KR1020137001143A patent/KR20130027551A/ko not_active Withdrawn
- 2011-06-16 NZ NZ603546A patent/NZ603546A/en not_active IP Right Cessation
- 2011-06-16 EP EP11727097.5A patent/EP2582786A1/en not_active Withdrawn
- 2011-06-16 MX MX2012014550A patent/MX2012014550A/es not_active Application Discontinuation
-
2012
- 2012-11-14 ZA ZA2012/08575A patent/ZA201208575B/en unknown
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