MX2014013446A - Enzimas de cetol-acido reductoisomerasa y metodos de uso. - Google Patents
Enzimas de cetol-acido reductoisomerasa y metodos de uso.Info
- Publication number
- MX2014013446A MX2014013446A MX2014013446A MX2014013446A MX2014013446A MX 2014013446 A MX2014013446 A MX 2014013446A MX 2014013446 A MX2014013446 A MX 2014013446A MX 2014013446 A MX2014013446 A MX 2014013446A MX 2014013446 A MX2014013446 A MX 2014013446A
- Authority
- MX
- Mexico
- Prior art keywords
- ketol
- methods
- acid reductoisomerase
- polypeptides
- reductoisomerase enzymes
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/16—Butanols
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/42—Hydroxy-carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/44—Polycarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01086—Ketol-acid reductoisomerase (1.1.1.86)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/645—Fungi ; Processes using fungi
- C12R2001/85—Saccharomyces
- C12R2001/865—Saccharomyces cerevisiae
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
En la presente descripción se proporcionan polipéptidos que tienen actividad cetol-ácido reductoisomerasa así como células hospederas microbianas que comprenden tales polipéptidos. Los polipéptidos proporcionados en la presente descripción pueden usarse en rutas biosintéticas que incluyen, pero no se limitan a, las rutas biosintéticas del isobutanol.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261645832P | 2012-05-11 | 2012-05-11 | |
US201361787480P | 2013-03-15 | 2013-03-15 | |
PCT/US2013/040627 WO2013176909A2 (en) | 2012-05-11 | 2013-05-10 | Ketol-acid reductoisomerase enzymes and methods of use |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2014013446A true MX2014013446A (es) | 2014-12-08 |
Family
ID=48877508
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014013446A MX2014013446A (es) | 2012-05-11 | 2013-05-10 | Enzimas de cetol-acido reductoisomerasa y metodos de uso. |
MX2018004620A MX370134B (es) | 2012-05-11 | 2013-05-10 | Enzimas de cetol-acido reductoisomerasa y metodo de uso. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2018004620A MX370134B (es) | 2012-05-11 | 2013-05-10 | Enzimas de cetol-acido reductoisomerasa y metodo de uso. |
Country Status (12)
Country | Link |
---|---|
US (2) | US9169467B2 (es) |
EP (1) | EP2847326A2 (es) |
JP (1) | JP6321631B2 (es) |
KR (1) | KR20150014953A (es) |
CN (1) | CN104619835B (es) |
AU (1) | AU2013266727A1 (es) |
BR (1) | BR112014028153A2 (es) |
CA (1) | CA2873109A1 (es) |
MX (2) | MX2014013446A (es) |
NZ (1) | NZ701099A (es) |
WO (1) | WO2013176909A2 (es) |
ZA (1) | ZA201407713B (es) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8945899B2 (en) | 2007-12-20 | 2015-02-03 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase using NADH |
US7910342B2 (en) | 2007-04-18 | 2011-03-22 | Butamax(Tm) Advanced Biofuels Llc | Fermentive production of isobutanol using highly active ketol-acid reductoisomerase enzymes |
US8188250B2 (en) | 2008-04-28 | 2012-05-29 | Butamax(Tm) Advanced Biofuels Llc | Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans |
EP2337856A1 (en) | 2008-09-29 | 2011-06-29 | Butamax Advanced Biofuels Llc | INCREASED HETEROLOGOUS Fe-S ENZYME ACTIIVTY IN YEAST |
CA2784903A1 (en) | 2009-12-29 | 2011-07-28 | Butamax(Tm) Advanced Biofuels Llc | Alcohol dehydrogenases (adh) useful for fermentive production of lower alkyl alcohols |
EP2536821B1 (en) | 2010-02-17 | 2018-06-13 | Butamax(TM) Advanced Biofuels LLC | Improving activity of fe-s cluster requiring proteins |
NZ722791A (en) | 2010-09-07 | 2018-12-21 | Butamax Tm Advanced Biofuels | Integration of a polynucleotide encoding a polypeptide that catalyzes pyruvate to acetolactate conversion |
JP6099623B2 (ja) | 2011-03-24 | 2017-03-22 | ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー | イソブタノール生成のための宿主細胞及び方法 |
EP2737073B1 (en) | 2011-07-28 | 2021-10-20 | Butamax Advanced Biofuels LLC | Keto-isovalerate decarboxylase enzymes and methods of use thereof |
CN104321436A (zh) | 2011-12-30 | 2015-01-28 | 布特马斯先进生物燃料有限责任公司 | 醇类的发酵生产 |
WO2013142338A1 (en) | 2012-03-23 | 2013-09-26 | Butamax(Tm) Advanced Biofuels Llc | Acetate supplemention of medium for butanologens |
KR20150014953A (ko) | 2012-05-11 | 2015-02-09 | 부타맥스 어드밴스드 바이오퓨얼스 엘엘씨 | 케톨-산 리덕토아이소머라아제 효소 및 사용 방법 |
EP2888350A1 (en) | 2012-08-22 | 2015-07-01 | Butamax Advanced Biofuels LLC | Production of fermentation products |
WO2014047421A1 (en) | 2012-09-21 | 2014-03-27 | Butamax(Tm) Advanced Biofuels Llc | Production of renewable hydrocarbon compositions |
WO2014052670A1 (en) | 2012-09-26 | 2014-04-03 | Butamax (Tm) Advanced Biofuels Llc | Polypeptides with ketol-acid reductoisomerase activity |
US9273330B2 (en) | 2012-10-03 | 2016-03-01 | Butamax Advanced Biofuels Llc | Butanol tolerance in microorganisms |
US9650624B2 (en) | 2012-12-28 | 2017-05-16 | Butamax Advanced Biofuels Llc | DHAD variants for butanol production |
CN105378057A (zh) | 2013-03-14 | 2016-03-02 | 纳幕尔杜邦公司 | 用于丁醇生产的甘油3-磷酸脱氢酶 |
US9771602B2 (en) | 2013-03-15 | 2017-09-26 | Butamax Advanced Biofuels Llc | Competitive growth and/or production advantage for butanologen microorganism |
WO2014151190A1 (en) | 2013-03-15 | 2014-09-25 | Butamax Advanced Biofuels Llc | Dhad variants and methods of screening |
WO2016025425A1 (en) | 2014-08-11 | 2016-02-18 | Butamax Advanced Biofuels Llc | Yeast preparations and methods of making the same |
BR112019009415A2 (pt) | 2016-11-09 | 2019-07-30 | Danisco Us Inc | levadura com a produção de álcool melhorada |
CN108728477B (zh) * | 2017-04-24 | 2022-02-22 | 华东理工大学 | 一种高效的转座突变系统及构建方法 |
KR101960501B1 (ko) * | 2017-09-15 | 2019-03-21 | 고려대학교 산학협력단 | Nadh 친화적인 신규 케톨산 리덕토아이소머라제 |
US11308274B2 (en) | 2019-05-17 | 2022-04-19 | International Business Machines Corporation | Word grouping using a plurality of models |
CN113278568B (zh) * | 2020-05-27 | 2022-10-21 | 安徽华恒生物科技股份有限公司 | 生产l-缬氨酸的重组大肠杆菌及其应用 |
Family Cites Families (75)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
US4865973A (en) | 1985-09-13 | 1989-09-12 | Queen's University At Kingston | Process for extractive fermentation |
FR2696190B1 (fr) | 1992-09-25 | 1994-12-09 | Agronomique Inst Nat Rech | Acide nucléique codant pour une alpha-acétolactate synthase et ses applications. |
CN101024843A (zh) | 1999-08-18 | 2007-08-29 | 纳幕尔杜邦公司 | 用于生产高效价1,3-丙二醇的生物学方法 |
AU2001249345A1 (en) | 2000-03-21 | 2001-10-03 | Elitra Pharmaceuticals, Inc. | Identification of essential genes in prokaryotes |
US6586229B1 (en) | 2000-06-01 | 2003-07-01 | North Carolina State University | Method for the production of ρ-Hydroxybenzoate in species of pseudomonas and agrobacterium |
IL159368A0 (en) | 2001-07-02 | 2004-06-01 | Kaneka Corp | Method of modifying enzyme and oxidoreductase variant |
EP1603406B1 (en) | 2003-03-10 | 2012-10-24 | POET Research, Inc. | Method for producing ethanol using raw starch |
SE526429C2 (sv) | 2003-10-24 | 2005-09-13 | Swedish Biofuels Ab | Metod för att framställa syreinnehållande föreningar utgående från biomassa |
JP5804666B2 (ja) | 2005-04-12 | 2015-11-04 | イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニーE.I.Du Pont De Nemours And Company | バイオマスの処理および利用における別の供給流れの集中 |
US9297028B2 (en) | 2005-09-29 | 2016-03-29 | Butamax Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
US9303225B2 (en) | 2005-10-26 | 2016-04-05 | Butamax Advanced Biofuels Llc | Method for the production of isobutanol by recombinant yeast |
JP5276986B2 (ja) | 2005-10-26 | 2013-08-28 | ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー | 四炭素アルコールの発酵性生産 |
US8273558B2 (en) * | 2005-10-26 | 2012-09-25 | Butamax(Tm) Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
US8945899B2 (en) * | 2007-12-20 | 2015-02-03 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase using NADH |
US8206970B2 (en) | 2006-05-02 | 2012-06-26 | Butamax(Tm) Advanced Biofuels Llc | Production of 2-butanol and 2-butanone employing aminobutanol phosphate phospholyase |
US8828704B2 (en) | 2006-05-02 | 2014-09-09 | Butamax Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
US7659104B2 (en) | 2006-05-05 | 2010-02-09 | E.I. Du Pont De Nemours And Company | Solvent tolerant microorganisms and methods of isolation |
US7541173B2 (en) | 2006-06-15 | 2009-06-02 | E.I. Du Pont De Nemours And Company | Solvent tolerant microorganisms and methods of isolation |
US8017364B2 (en) | 2006-12-12 | 2011-09-13 | Butamax(Tm) Advanced Biofuels Llc | Solvent tolerant microorganisms |
CN103540559A (zh) | 2007-02-09 | 2014-01-29 | 加利福尼亚大学董事会 | 利用重组微生物生产生物燃料 |
US7910342B2 (en) | 2007-04-18 | 2011-03-22 | Butamax(Tm) Advanced Biofuels Llc | Fermentive production of isobutanol using highly active ketol-acid reductoisomerase enzymes |
EP2060632A1 (en) | 2007-10-29 | 2009-05-20 | Technische Universität Berlin | Method of modifying a yeast cell for the production of ethanol |
EP2215243A2 (en) | 2007-10-31 | 2010-08-11 | GEVO, Inc. | Methods for the economical production of biofuel precursor that is also a biofuel from biomass |
US8043638B2 (en) | 2007-12-17 | 2011-10-25 | Suntory Holdings Limited | Mutant ILV5 gene and use thereof |
ES2553726T3 (es) | 2007-12-20 | 2015-12-11 | Butamax (Tm) Advanced Biofuels Llc | Cetol-ácido reductoisomerasa que utiliza NADH |
US8518678B2 (en) | 2007-12-21 | 2013-08-27 | Butamax(Tm) Advanced Biofuels Llc | Strain comprising increased expression of a CFA coding region for butanol production |
US8372612B2 (en) | 2007-12-21 | 2013-02-12 | Butamax(Tm) Advanced Biofuels Llc | Production of four carbon alcohols using improved strain |
ES2563040T3 (es) | 2007-12-23 | 2016-03-10 | Gevo, Inc. | Organismo de levadura que produce isobutanol a un alto rendimiento |
US8188250B2 (en) | 2008-04-28 | 2012-05-29 | Butamax(Tm) Advanced Biofuels Llc | Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans |
US8389252B2 (en) | 2008-05-12 | 2013-03-05 | Butamax(Tm) Advanced Biofuels Llc | Yeast strain for production of four carbon alcohols |
WO2009143455A2 (en) | 2008-05-22 | 2009-11-26 | Microbia, Inc. | Engineering resistance to aliphatic alcohols |
BRPI0909989A2 (pt) | 2008-06-05 | 2021-06-22 | Butamax Advanced Biofuels Llc | célula de levedura recombinante e método para a produção de um produto |
US20100081182A1 (en) | 2008-09-29 | 2010-04-01 | Butamax(Tm) Advanced Biofuels Llc | Enhanced iron-sulfur cluster formation for increased dihydroxy-acid dehydratase activity in lactic acid bacteria |
MX2011003238A (es) | 2008-09-29 | 2011-04-28 | Butamax Tm Advanced Biofuels | Identificacion y uso de dihidroxiacido deshidratasas [2fe-2s] bacterianas. |
US8455224B2 (en) | 2008-09-29 | 2013-06-04 | Butamax(Tm) Advanced Biofuels Llc | Enhanced pyruvate to 2,3-butanediol conversion in lactic acid bacteria |
EP2331683A1 (en) | 2008-09-29 | 2011-06-15 | Butamax Advanced Biofuels Llc | Enhanced dihydroxy-acid dehydratase activity in lactic acid bacteria |
EP2337856A1 (en) | 2008-09-29 | 2011-06-29 | Butamax Advanced Biofuels Llc | INCREASED HETEROLOGOUS Fe-S ENZYME ACTIIVTY IN YEAST |
CA2737112A1 (en) | 2008-10-27 | 2010-06-03 | Butamax Advanced Biofuels Llc | Carbon pathway optimized production hosts for the production of isobutanol |
US20100143997A1 (en) | 2008-10-31 | 2010-06-10 | Thomas Buelter | Engineered microorganisms capable of producing target compounds under anaerobic conditions |
US8465964B2 (en) | 2008-11-13 | 2013-06-18 | Butamax (TM) Advanced Biofules LLC | Increased production of isobutanol in yeast with reduced mitochondrial amino acid biosynthesis |
US8828694B2 (en) | 2008-11-13 | 2014-09-09 | Butamax Advanced Biofuels Llc | Production of isobutanol in yeast mitochondria |
US8652823B2 (en) | 2008-12-03 | 2014-02-18 | Butamax(Tm) Advanced Biofuels Llc | Strain for butanol production with increased membrane unsaturated trans fatty acids |
US8795992B2 (en) | 2008-12-29 | 2014-08-05 | Butamax Advanced Biofuels Llc | Yeast with increased butanol tolerance involving cell wall integrity pathway |
US8557562B2 (en) | 2008-12-29 | 2013-10-15 | Butamax(Tm) Advanced Biofuels Llc | Yeast with increased butanol tolerance involving filamentous growth response |
US8455225B2 (en) | 2008-12-29 | 2013-06-04 | Butamax Advanced Biofuels Llc | Yeast with increased butanol tolerance involving high osmolarity/glycerol response pathway |
US8614085B2 (en) | 2009-02-27 | 2013-12-24 | Butamax(Tm) Advanced Biofuels Llc | Yeast with increased butanol tolerance involving a multidrug efflux pump gene |
US20120058541A1 (en) | 2009-05-22 | 2012-03-08 | Butamax(Tm) Advanced Biofuels Llc | Engineering resistance to aliphatic alcohols |
EP2464736A4 (en) | 2009-08-12 | 2013-07-31 | Gevo Inc | PATIENT LOCALIZATION OF CYTOSOLIC ISOBUTANOL FOR THE MANUFACTURE OF ISOBUTANOL |
JP5805094B2 (ja) | 2009-09-29 | 2015-11-04 | ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー | 高有効性のケトール酸レダクトイソメラーゼ酵素を用いたイソブタノールの発酵生産 |
WO2011041426A1 (en) | 2009-09-29 | 2011-04-07 | Butamax(Tm) Advanced Biofuels Llc | Improved yeast production host cells |
AU2010300722A1 (en) | 2009-09-29 | 2012-04-12 | Butamax(Tm) Advanced Biofuels Llc | Improved flux to acetolactate-derived products in lactic acid bacteria |
US20110195505A1 (en) | 2009-10-08 | 2011-08-11 | Butamax(Tm) Advanced Biofuels Llc | Bacterial strains for butanol production |
BR112012012492A2 (pt) | 2009-11-24 | 2019-09-24 | Gevo Inc | métodos para aumentar atividade de diidróxi ácido desidratase para aperfeiçoar produção de combustíveis, produtos químicos e aminoácidos |
MX2012007712A (es) | 2009-12-29 | 2012-08-15 | Butamax Tm Advanced Biofuels | Expresion de hexosa cinasa en celulas huesped recombinantes. |
CA2784903A1 (en) | 2009-12-29 | 2011-07-28 | Butamax(Tm) Advanced Biofuels Llc | Alcohol dehydrogenases (adh) useful for fermentive production of lower alkyl alcohols |
RU2012138943A (ru) | 2010-02-12 | 2014-03-20 | Джево, Инк. | Дрожжевые микроорганизмы с пониженным накоплением побочных продуктов для улучшенного производства топлив, химикатов и аминокислот |
EP2536821B1 (en) | 2010-02-17 | 2018-06-13 | Butamax(TM) Advanced Biofuels LLC | Improving activity of fe-s cluster requiring proteins |
NZ603546A (en) * | 2010-06-17 | 2014-10-31 | Butamax Tm Advanced Biofuels | Yeast production culture for the production of butanol |
US8871488B2 (en) | 2010-06-18 | 2014-10-28 | Butamax Advanced Biofuels Llc | Recombinant host cells comprising phosphoketolases |
NZ722791A (en) * | 2010-09-07 | 2018-12-21 | Butamax Tm Advanced Biofuels | Integration of a polynucleotide encoding a polypeptide that catalyzes pyruvate to acetolactate conversion |
JP6099623B2 (ja) | 2011-03-24 | 2017-03-22 | ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー | イソブタノール生成のための宿主細胞及び方法 |
US20120258873A1 (en) | 2011-04-06 | 2012-10-11 | Butamax(Tm) Advanced Biofuels Llc | Reduction of 2,3-dihydroxy-2-methyl butyrate (dhmb) in butanol production |
WO2012173659A2 (en) | 2011-06-17 | 2012-12-20 | Butamax (Tm) Advanced Biofuels Llc | Lignocellulosic hydrolysates as feedstocks for isobutanol fermentation |
EP2737073B1 (en) | 2011-07-28 | 2021-10-20 | Butamax Advanced Biofuels LLC | Keto-isovalerate decarboxylase enzymes and methods of use thereof |
CN104321436A (zh) | 2011-12-30 | 2015-01-28 | 布特马斯先进生物燃料有限责任公司 | 醇类的发酵生产 |
CN104284980A (zh) | 2011-12-30 | 2015-01-14 | 布特马斯先进生物燃料有限责任公司 | 用于丁醇生产的基因开关 |
WO2013142338A1 (en) | 2012-03-23 | 2013-09-26 | Butamax(Tm) Advanced Biofuels Llc | Acetate supplemention of medium for butanologens |
KR20150014953A (ko) | 2012-05-11 | 2015-02-09 | 부타맥스 어드밴스드 바이오퓨얼스 엘엘씨 | 케톨-산 리덕토아이소머라아제 효소 및 사용 방법 |
WO2014052670A1 (en) | 2012-09-26 | 2014-04-03 | Butamax (Tm) Advanced Biofuels Llc | Polypeptides with ketol-acid reductoisomerase activity |
US9273330B2 (en) | 2012-10-03 | 2016-03-01 | Butamax Advanced Biofuels Llc | Butanol tolerance in microorganisms |
US9650624B2 (en) | 2012-12-28 | 2017-05-16 | Butamax Advanced Biofuels Llc | DHAD variants for butanol production |
US20140186911A1 (en) | 2012-12-28 | 2014-07-03 | Butamax Advanced Biofuels Llc | Recombinant host cells and methods for producing butanol |
CN105378057A (zh) | 2013-03-14 | 2016-03-02 | 纳幕尔杜邦公司 | 用于丁醇生产的甘油3-磷酸脱氢酶 |
WO2014151190A1 (en) | 2013-03-15 | 2014-09-25 | Butamax Advanced Biofuels Llc | Dhad variants and methods of screening |
-
2013
- 2013-05-10 KR KR1020147034485A patent/KR20150014953A/ko not_active Application Discontinuation
- 2013-05-10 JP JP2015511775A patent/JP6321631B2/ja active Active
- 2013-05-10 CA CA2873109A patent/CA2873109A1/en not_active Abandoned
- 2013-05-10 MX MX2014013446A patent/MX2014013446A/es unknown
- 2013-05-10 AU AU2013266727A patent/AU2013266727A1/en not_active Abandoned
- 2013-05-10 EP EP13742293.7A patent/EP2847326A2/en not_active Withdrawn
- 2013-05-10 WO PCT/US2013/040627 patent/WO2013176909A2/en active Application Filing
- 2013-05-10 NZ NZ701099A patent/NZ701099A/en unknown
- 2013-05-10 CN CN201380036539.6A patent/CN104619835B/zh active Active
- 2013-05-10 MX MX2018004620A patent/MX370134B/es unknown
- 2013-05-10 BR BR112014028153-0A patent/BR112014028153A2/pt not_active Application Discontinuation
- 2013-05-10 US US13/891,963 patent/US9169467B2/en active Active
-
2014
- 2014-10-23 ZA ZA2014/07713A patent/ZA201407713B/en unknown
-
2015
- 2015-09-14 US US14/853,108 patent/US9388392B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
CA2873109A1 (en) | 2013-11-28 |
US20160032255A1 (en) | 2016-02-04 |
MX370134B (es) | 2019-12-03 |
ZA201407713B (en) | 2016-05-25 |
JP6321631B2 (ja) | 2018-05-09 |
US20140051133A1 (en) | 2014-02-20 |
NZ701099A (en) | 2017-04-28 |
EP2847326A2 (en) | 2015-03-18 |
AU2013266727A1 (en) | 2014-11-06 |
KR20150014953A (ko) | 2015-02-09 |
US9169467B2 (en) | 2015-10-27 |
CN104619835B (zh) | 2018-06-19 |
CN104619835A (zh) | 2015-05-13 |
WO2013176909A2 (en) | 2013-11-28 |
US9388392B2 (en) | 2016-07-12 |
BR112014028153A2 (pt) | 2018-05-08 |
WO2013176909A3 (en) | 2014-02-13 |
JP2015517310A (ja) | 2015-06-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NZ701099A (en) | Ketol-acid reductoisomerase enzymes and methods of use | |
MX2019008428A (es) | Inhibidores de glucosilceramida sintasa. | |
TN2015000091A1 (en) | Glucosylceramide synthase inhibitors | |
EP2811011A4 (en) | CELL CULTURE KIT AND METHOD FOR USING THE CELL CULTURE KIT | |
WO2012104007A3 (de) | 7-azaindolderivate | |
CL2013000238A1 (es) | Uso de inhibores de la succinato deshidrogenasa y/o inhibidores del complejo iii para mejorar la relacion entre microorganismos dañinos y beneficiosos. | |
IN2014CN02100A (es) | ||
EP2723263A4 (en) | SYSTEMS, DEVICES, AND METHODS FOR INDUCING PROGRAMMED CELL DEATH OF ADIPOSE TISSUES | |
BR112014024675A8 (pt) | célula hospedeira recombinante, cultura celular | |
IN2014MN00989A (es) | ||
NZ606589A (en) | 5-chloro-4-hydroxy-1-methyl-2-oxo-n-phenyl-1,2-dihydroquinoline-3-carboxamide, salts and uses thereof | |
EP2714709A4 (en) | CELL-BASED AND GENE-BASED METHODS FOR ENHANCING CARDIAC FUNCTION | |
PL2751279T3 (pl) | Sposoby i kompozycje do wykrywania poziomu aktywności lizosomalnej egzocytozy i sposoby zastosowania | |
EP2880050A4 (en) | NOVEL ENZYMES, ENZYME COMPONENTS AND USES THEREOF | |
SG10201804952QA (en) | Glucosylceramide synthase inhibitors | |
EP2872167A4 (en) | TOPICAL FORMULATIONS CONTAINING DNA REPAIR ENZYMES AND METHODS OF USING THE SAME | |
EP2865394A4 (en) | MAGNETICALLY FUNCTIONALITY COMPOUNDS, IMPLANTS OR GELS DERIVED THEREFROM, AND USE THEREOF FOR DETERMINING THE ENZYMATIC ACTIVITY OF AN ENZYME | |
MX2014003318A (es) | Actividad de adnasa endogena para reducir el contenido de adn. | |
EP2878663A4 (en) | CELL CULTURE CONTAINER HAVING DOUBLE STRUCTURE, AND CIRCULATION CULTURE SYSTEM USING SAME | |
MX365464B (es) | Prodecimiento para preparar inhibidores de la glucosilceramida sintasa. | |
EP3049529A4 (en) | Engineered enzyme having acetoacetyl-coa hydrolase activity, microorganisms comprising same, and methods of using same | |
TN2013000368A1 (en) | Glucosylceramide synthase inhibitors | |
UA55887U (ru) | Способ диагностики риска прогрессии гиперплазии эндометрия в передрак и рак эндометрия | |
EP2841408A4 (en) | METHODS OF MAINTAINING AND IMPROVING CELL BIOLOGICAL FUNCTION AND ACTIVITY | |
SG2012070058A (en) | Cleavable cellulosic sponge development for 3 dimensional cell culture and spheroids retrieval |