MX370134B - Enzimas de cetol-acido reductoisomerasa y metodo de uso. - Google Patents
Enzimas de cetol-acido reductoisomerasa y metodo de uso.Info
- Publication number
- MX370134B MX370134B MX2018004620A MX2018004620A MX370134B MX 370134 B MX370134 B MX 370134B MX 2018004620 A MX2018004620 A MX 2018004620A MX 2018004620 A MX2018004620 A MX 2018004620A MX 370134 B MX370134 B MX 370134B
- Authority
- MX
- Mexico
- Prior art keywords
- ketol
- methods
- acid reductoisomerase
- polypeptides
- reductoisomerase enzymes
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/16—Butanols
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/42—Hydroxy-carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/44—Polycarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01086—Ketol-acid reductoisomerase (1.1.1.86)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/645—Fungi ; Processes using fungi
- C12R2001/85—Saccharomyces
- C12R2001/865—Saccharomyces cerevisiae
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
La presente invención se refiere a polipéptidos que tienen actividad cetol-ácido reductoisomerasa así como células hospederas microbianas que comprenden tales polipéptidos. Los polipéptidos proporcionados en la presente descripción pueden usarse en rutas biosintéticas que incluyen, pero no se limitan a, las rutas biosintéticas del isobutanol.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261645832P | 2012-05-11 | 2012-05-11 | |
US201361787480P | 2013-03-15 | 2013-03-15 | |
PCT/US2013/040627 WO2013176909A2 (en) | 2012-05-11 | 2013-05-10 | Ketol-acid reductoisomerase enzymes and methods of use |
Publications (1)
Publication Number | Publication Date |
---|---|
MX370134B true MX370134B (es) | 2019-12-03 |
Family
ID=48877508
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014013446A MX2014013446A (es) | 2012-05-11 | 2013-05-10 | Enzimas de cetol-acido reductoisomerasa y metodos de uso. |
MX2018004620A MX370134B (es) | 2012-05-11 | 2013-05-10 | Enzimas de cetol-acido reductoisomerasa y metodo de uso. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014013446A MX2014013446A (es) | 2012-05-11 | 2013-05-10 | Enzimas de cetol-acido reductoisomerasa y metodos de uso. |
Country Status (12)
Country | Link |
---|---|
US (2) | US9169467B2 (es) |
EP (1) | EP2847326A2 (es) |
JP (1) | JP6321631B2 (es) |
KR (1) | KR20150014953A (es) |
CN (1) | CN104619835B (es) |
AU (1) | AU2013266727A1 (es) |
BR (1) | BR112014028153A2 (es) |
CA (1) | CA2873109A1 (es) |
MX (2) | MX2014013446A (es) |
NZ (1) | NZ701099A (es) |
WO (1) | WO2013176909A2 (es) |
ZA (1) | ZA201407713B (es) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8945899B2 (en) | 2007-12-20 | 2015-02-03 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase using NADH |
EP2134849B1 (en) | 2007-04-18 | 2013-07-10 | Butamax (TM) Advanced Biofuels LLC | Fermentive production of isobutanol using highly active ketol-acid reductoisomerase enzymes |
US8188250B2 (en) | 2008-04-28 | 2012-05-29 | Butamax(Tm) Advanced Biofuels Llc | Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans |
NZ591126A (en) | 2008-09-29 | 2012-08-31 | Butamax Tm Advanced Biofuels | INCREASED HETEROLOGOUS Fe-S ENZYME ACTIIVTY IN YEAST |
NZ600509A (en) | 2009-12-29 | 2014-08-29 | Butamax Tm Advanced Biofuels | Alcohol dehydrogenases (adh) useful for fermentive production of lower alkyl alcohols |
NZ601241A (en) | 2010-02-17 | 2014-08-29 | Butamax Tm Advanced Biofuels | Improving activity of fe-s cluster requiring proteins |
NZ707800A (en) | 2010-09-07 | 2016-09-30 | Butamax Tm Advanced Biofuels | Integration of a polynucleotide encoding a polypeptide that catalyzes pyruvate to acetolactate conversion |
MX347976B (es) | 2011-03-24 | 2017-05-22 | Butamax(Tm) Advanced Biofuels Llc | Celulas huesped y metodos para producir isobutanol. |
CA2849877A1 (en) | 2011-07-28 | 2013-01-31 | Butamax Advanced Biofuels Llc | Keto-isovalerate decarboxylase enzymes and methods of use thereof |
EP2798072A2 (en) | 2011-12-30 | 2014-11-05 | Butamax Advanced Biofuels LLC | Fermentative production of alcohols |
MX2014011355A (es) | 2012-03-23 | 2014-12-05 | Butamax Advanced Biofuels Llc | Complementacion con acetato de medio para butanologenos. |
NZ701099A (en) | 2012-05-11 | 2017-04-28 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase enzymes and methods of use |
EP2888350A1 (en) | 2012-08-22 | 2015-07-01 | Butamax Advanced Biofuels LLC | Production of fermentation products |
WO2014047421A1 (en) | 2012-09-21 | 2014-03-27 | Butamax(Tm) Advanced Biofuels Llc | Production of renewable hydrocarbon compositions |
BR112015006691A2 (pt) | 2012-09-26 | 2017-12-12 | Butamax Advanced Biofuels Llc | métodos, célula hospedeira recombinante, composição, polipeptídeo, polinucleotídeos e vetor recombinante |
US9273330B2 (en) | 2012-10-03 | 2016-03-01 | Butamax Advanced Biofuels Llc | Butanol tolerance in microorganisms |
US9650624B2 (en) | 2012-12-28 | 2017-05-16 | Butamax Advanced Biofuels Llc | DHAD variants for butanol production |
CA2905912A1 (en) | 2013-03-14 | 2014-10-02 | E. I. Du Pont De Nemours And Company | Glycerol 3- phosphate dehydrogenase for butanol production |
WO2014151190A1 (en) | 2013-03-15 | 2014-09-25 | Butamax Advanced Biofuels Llc | Dhad variants and methods of screening |
US9771602B2 (en) | 2013-03-15 | 2017-09-26 | Butamax Advanced Biofuels Llc | Competitive growth and/or production advantage for butanologen microorganism |
EP3180440A4 (en) | 2014-08-11 | 2018-01-10 | Butamax Advanced Biofuels LLC | Yeast preparations and methods of making the same |
WO2018089333A1 (en) | 2016-11-09 | 2018-05-17 | Danisco Us Inc. | Yeast with improved alcohol production |
CN108728477B (zh) * | 2017-04-24 | 2022-02-22 | 华东理工大学 | 一种高效的转座突变系统及构建方法 |
KR101960501B1 (ko) * | 2017-09-15 | 2019-03-21 | 고려대학교 산학협력단 | Nadh 친화적인 신규 케톨산 리덕토아이소머라제 |
US11308274B2 (en) | 2019-05-17 | 2022-04-19 | International Business Machines Corporation | Word grouping using a plurality of models |
CN113278568B (zh) * | 2020-05-27 | 2022-10-21 | 安徽华恒生物科技股份有限公司 | 生产l-缬氨酸的重组大肠杆菌及其应用 |
Family Cites Families (75)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
US4865973A (en) | 1985-09-13 | 1989-09-12 | Queen's University At Kingston | Process for extractive fermentation |
FR2696190B1 (fr) | 1992-09-25 | 1994-12-09 | Agronomique Inst Nat Rech | Acide nucléique codant pour une alpha-acétolactate synthase et ses applications. |
BRPI0013315B8 (pt) | 1999-08-18 | 2018-02-27 | Du Pont | fragmento de ácido nucleico isolado, polipeptídeo, gene quimérico, microorganismo, microorganismo recombinante , e. coli recombinante, linhagem klp23 de e. coli recombinante, linhagem rj8 de e. coli recombinante, vetor pdt29, vetor pkp32 e processos de bioprodução de 1,3-propanodiol |
EP1268774A2 (en) | 2000-03-21 | 2003-01-02 | Elitra Pharmaceuticals, Inc. | Identification of essential genes in prokaryotes |
US6586229B1 (en) | 2000-06-01 | 2003-07-01 | North Carolina State University | Method for the production of ρ-Hydroxybenzoate in species of pseudomonas and agrobacterium |
US20040248250A1 (en) | 2001-07-02 | 2004-12-09 | Takahisa Nakai | Method for modifying enzyme and oxidoreductive variant |
BRPI0408215B1 (pt) | 2003-03-10 | 2015-11-03 | Broin And Associates Inc | processo para a produção de etanol usando amido bruto |
SE526429C2 (sv) | 2003-10-24 | 2005-09-13 | Swedish Biofuels Ab | Metod för att framställa syreinnehållande föreningar utgående från biomassa |
US7932063B2 (en) | 2005-04-12 | 2011-04-26 | E. I. Du Pont De Nemours And Company | Treatment of biomass to obtain fermentable sugars |
US9297028B2 (en) | 2005-09-29 | 2016-03-29 | Butamax Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
US9303225B2 (en) | 2005-10-26 | 2016-04-05 | Butamax Advanced Biofuels Llc | Method for the production of isobutanol by recombinant yeast |
US8129162B2 (en) * | 2007-12-20 | 2012-03-06 | Butamax(Tm) Advanced Biofuels Llc | Ketol-acid reductoisomerase using NADH |
US8945899B2 (en) | 2007-12-20 | 2015-02-03 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase using NADH |
NZ593809A (en) | 2005-10-26 | 2013-01-25 | Butamax Tm Advanced Biofuels | Fermentive production of four carbon alcohols |
US8273558B2 (en) * | 2005-10-26 | 2012-09-25 | Butamax(Tm) Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
US8956850B2 (en) | 2008-06-05 | 2015-02-17 | Butamax Advanced Biofuels Llc | Enhanced pyruvate to acetolactate conversion in yeast |
US8962298B2 (en) | 2006-05-02 | 2015-02-24 | Butamax Advanced Biofuels Llc | Recombinant host cell comprising a diol dehydratase |
US8828704B2 (en) | 2006-05-02 | 2014-09-09 | Butamax Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
US7659104B2 (en) | 2006-05-05 | 2010-02-09 | E.I. Du Pont De Nemours And Company | Solvent tolerant microorganisms and methods of isolation |
US7541173B2 (en) | 2006-06-15 | 2009-06-02 | E.I. Du Pont De Nemours And Company | Solvent tolerant microorganisms and methods of isolation |
US8017364B2 (en) | 2006-12-12 | 2011-09-13 | Butamax(Tm) Advanced Biofuels Llc | Solvent tolerant microorganisms |
EP2118266A4 (en) | 2007-02-09 | 2010-05-19 | Univ California | BIOFUEL PRODUCTION BY RECOMBINANT MICROORGANISMS |
EP2134849B1 (en) | 2007-04-18 | 2013-07-10 | Butamax (TM) Advanced Biofuels LLC | Fermentive production of isobutanol using highly active ketol-acid reductoisomerase enzymes |
EP2060632A1 (en) | 2007-10-29 | 2009-05-20 | Technische Universität Berlin | Method of modifying a yeast cell for the production of ethanol |
EP2215243A2 (en) | 2007-10-31 | 2010-08-11 | GEVO, Inc. | Methods for the economical production of biofuel precursor that is also a biofuel from biomass |
CN101679985B (zh) | 2007-12-17 | 2012-11-14 | 三得利控股株式会社 | 突变ilv5基因及其用途 |
US8518678B2 (en) | 2007-12-21 | 2013-08-27 | Butamax(Tm) Advanced Biofuels Llc | Strain comprising increased expression of a CFA coding region for butanol production |
US8372612B2 (en) | 2007-12-21 | 2013-02-12 | Butamax(Tm) Advanced Biofuels Llc | Production of four carbon alcohols using improved strain |
CN101952448A (zh) | 2007-12-23 | 2011-01-19 | 格沃股份有限公司 | 高产率产生异丁醇的酵母生物 |
US8188250B2 (en) | 2008-04-28 | 2012-05-29 | Butamax(Tm) Advanced Biofuels Llc | Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans |
US8389252B2 (en) | 2008-05-12 | 2013-03-05 | Butamax(Tm) Advanced Biofuels Llc | Yeast strain for production of four carbon alcohols |
US8906666B2 (en) | 2008-05-22 | 2014-12-09 | Butamax Advanced Biofuels Llc | Engineering resistance to aliphatic alcohols |
CA2736420A1 (en) | 2008-09-29 | 2010-04-01 | Butamaxtm Advanced Biofuels Llc | Enhanced dihydroxy-acid dehydratase activity in lactic acid bacteria |
NZ591126A (en) | 2008-09-29 | 2012-08-31 | Butamax Tm Advanced Biofuels | INCREASED HETEROLOGOUS Fe-S ENZYME ACTIIVTY IN YEAST |
WO2010037119A1 (en) | 2008-09-29 | 2010-04-01 | Butamax™ Advanced Biofuels LLC | Enhanced iron-sulfur cluster formation for increased dihydroxy-acid dehydratase activity in lactic acid bacteria |
AU2009296227A1 (en) | 2008-09-29 | 2010-04-01 | Butamax(Tm) Advanced Biofuels Llc | Enhanced pyruvate to 2,3-butanediol conversion in lactic acid bacteria |
US20100081154A1 (en) | 2008-09-29 | 2010-04-01 | Butamax(Tm) Advanced Biofuels Llc | IDENTIFICATION AND USE OF BACTERIAL [2Fe-2S] DIHYDROXY-ACID DEHYDRATASES |
AU2009320163B2 (en) | 2008-10-27 | 2014-10-02 | Butamax(Tm) Advanced Biofuels Llc | Carbon pathway optimized production hosts for the production of isobutanol |
BRPI0921734A2 (pt) | 2008-10-31 | 2019-01-08 | California Inst Of Techn | micro-organismos criados geneticamente capazes de produzir compostos-alvo sob condições anaeróbicas |
US8465964B2 (en) | 2008-11-13 | 2013-06-18 | Butamax (TM) Advanced Biofules LLC | Increased production of isobutanol in yeast with reduced mitochondrial amino acid biosynthesis |
US8828694B2 (en) | 2008-11-13 | 2014-09-09 | Butamax Advanced Biofuels Llc | Production of isobutanol in yeast mitochondria |
US8652823B2 (en) | 2008-12-03 | 2014-02-18 | Butamax(Tm) Advanced Biofuels Llc | Strain for butanol production with increased membrane unsaturated trans fatty acids |
US8557562B2 (en) | 2008-12-29 | 2013-10-15 | Butamax(Tm) Advanced Biofuels Llc | Yeast with increased butanol tolerance involving filamentous growth response |
US8455225B2 (en) | 2008-12-29 | 2013-06-04 | Butamax Advanced Biofuels Llc | Yeast with increased butanol tolerance involving high osmolarity/glycerol response pathway |
US8795992B2 (en) | 2008-12-29 | 2014-08-05 | Butamax Advanced Biofuels Llc | Yeast with increased butanol tolerance involving cell wall integrity pathway |
US8614085B2 (en) | 2009-02-27 | 2013-12-24 | Butamax(Tm) Advanced Biofuels Llc | Yeast with increased butanol tolerance involving a multidrug efflux pump gene |
US20120058541A1 (en) | 2009-05-22 | 2012-03-08 | Butamax(Tm) Advanced Biofuels Llc | Engineering resistance to aliphatic alcohols |
CA2770842A1 (en) | 2009-08-12 | 2011-02-17 | Gevo, Inc. | Cytosolic isobutanol pathway localization for the production of isobutanol |
CN102666866A (zh) | 2009-09-29 | 2012-09-12 | 布特马斯先进生物燃料有限责任公司 | 使用高效酮醇酸还原异构酶发酵生产异丁醇 |
JP2013505739A (ja) | 2009-09-29 | 2013-02-21 | ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー | 乳酸菌におけるアセト乳酸誘導生成物への改善されたフラックス |
WO2011041426A1 (en) | 2009-09-29 | 2011-04-07 | Butamax(Tm) Advanced Biofuels Llc | Improved yeast production host cells |
US20110195505A1 (en) | 2009-10-08 | 2011-08-11 | Butamax(Tm) Advanced Biofuels Llc | Bacterial strains for butanol production |
GB2487889B (en) | 2009-11-24 | 2012-12-19 | Gevo Inc | Methods of increasing dihydroxy acid dehydratase activity to improve production of fuels, chemicals, and amino acids |
NZ600509A (en) | 2009-12-29 | 2014-08-29 | Butamax Tm Advanced Biofuels | Alcohol dehydrogenases (adh) useful for fermentive production of lower alkyl alcohols |
KR20120099509A (ko) | 2009-12-29 | 2012-09-10 | 부타맥스 어드밴스드 바이오퓨얼스 엘엘씨 | 재조합 숙주 세포에서 육탄당 키나아제의 발현 |
JP2013519376A (ja) | 2010-02-12 | 2013-05-30 | ジーヴォ,インコーポレイテッド | 燃料、化学物質、およびアミノ酸の改善された産生のための、低減された副産物蓄積を有する酵母微生物 |
NZ601241A (en) | 2010-02-17 | 2014-08-29 | Butamax Tm Advanced Biofuels | Improving activity of fe-s cluster requiring proteins |
EP2582786A1 (en) | 2010-06-17 | 2013-04-24 | Butamax(TM) Advanced Biofuels LLC | Yeast production culture for the production of butanol |
US8871488B2 (en) | 2010-06-18 | 2014-10-28 | Butamax Advanced Biofuels Llc | Recombinant host cells comprising phosphoketolases |
NZ707800A (en) * | 2010-09-07 | 2016-09-30 | Butamax Tm Advanced Biofuels | Integration of a polynucleotide encoding a polypeptide that catalyzes pyruvate to acetolactate conversion |
MX347976B (es) | 2011-03-24 | 2017-05-22 | Butamax(Tm) Advanced Biofuels Llc | Celulas huesped y metodos para producir isobutanol. |
US20120258873A1 (en) | 2011-04-06 | 2012-10-11 | Butamax(Tm) Advanced Biofuels Llc | Reduction of 2,3-dihydroxy-2-methyl butyrate (dhmb) in butanol production |
WO2012173659A2 (en) | 2011-06-17 | 2012-12-20 | Butamax (Tm) Advanced Biofuels Llc | Lignocellulosic hydrolysates as feedstocks for isobutanol fermentation |
CA2849877A1 (en) | 2011-07-28 | 2013-01-31 | Butamax Advanced Biofuels Llc | Keto-isovalerate decarboxylase enzymes and methods of use thereof |
AU2012362144A1 (en) | 2011-12-30 | 2014-07-03 | Butamax (Tm) Advanced Biofuels Llc | Genetic switches for butanol production |
EP2798072A2 (en) | 2011-12-30 | 2014-11-05 | Butamax Advanced Biofuels LLC | Fermentative production of alcohols |
MX2014011355A (es) | 2012-03-23 | 2014-12-05 | Butamax Advanced Biofuels Llc | Complementacion con acetato de medio para butanologenos. |
NZ701099A (en) | 2012-05-11 | 2017-04-28 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase enzymes and methods of use |
BR112015006691A2 (pt) | 2012-09-26 | 2017-12-12 | Butamax Advanced Biofuels Llc | métodos, célula hospedeira recombinante, composição, polipeptídeo, polinucleotídeos e vetor recombinante |
US9273330B2 (en) | 2012-10-03 | 2016-03-01 | Butamax Advanced Biofuels Llc | Butanol tolerance in microorganisms |
US9650624B2 (en) | 2012-12-28 | 2017-05-16 | Butamax Advanced Biofuels Llc | DHAD variants for butanol production |
US20140186911A1 (en) | 2012-12-28 | 2014-07-03 | Butamax Advanced Biofuels Llc | Recombinant host cells and methods for producing butanol |
CA2905912A1 (en) | 2013-03-14 | 2014-10-02 | E. I. Du Pont De Nemours And Company | Glycerol 3- phosphate dehydrogenase for butanol production |
WO2014151190A1 (en) | 2013-03-15 | 2014-09-25 | Butamax Advanced Biofuels Llc | Dhad variants and methods of screening |
-
2013
- 2013-05-10 NZ NZ701099A patent/NZ701099A/en unknown
- 2013-05-10 CA CA2873109A patent/CA2873109A1/en not_active Abandoned
- 2013-05-10 BR BR112014028153-0A patent/BR112014028153A2/pt not_active Application Discontinuation
- 2013-05-10 KR KR1020147034485A patent/KR20150014953A/ko not_active Application Discontinuation
- 2013-05-10 MX MX2014013446A patent/MX2014013446A/es unknown
- 2013-05-10 WO PCT/US2013/040627 patent/WO2013176909A2/en active Application Filing
- 2013-05-10 JP JP2015511775A patent/JP6321631B2/ja active Active
- 2013-05-10 EP EP13742293.7A patent/EP2847326A2/en not_active Withdrawn
- 2013-05-10 MX MX2018004620A patent/MX370134B/es unknown
- 2013-05-10 CN CN201380036539.6A patent/CN104619835B/zh active Active
- 2013-05-10 AU AU2013266727A patent/AU2013266727A1/en not_active Abandoned
- 2013-05-10 US US13/891,963 patent/US9169467B2/en active Active
-
2014
- 2014-10-23 ZA ZA2014/07713A patent/ZA201407713B/en unknown
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2015
- 2015-09-14 US US14/853,108 patent/US9388392B2/en active Active
Also Published As
Publication number | Publication date |
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BR112014028153A2 (pt) | 2018-05-08 |
AU2013266727A1 (en) | 2014-11-06 |
JP6321631B2 (ja) | 2018-05-09 |
US9169467B2 (en) | 2015-10-27 |
EP2847326A2 (en) | 2015-03-18 |
US20160032255A1 (en) | 2016-02-04 |
JP2015517310A (ja) | 2015-06-22 |
MX2014013446A (es) | 2014-12-08 |
WO2013176909A3 (en) | 2014-02-13 |
CN104619835A (zh) | 2015-05-13 |
WO2013176909A2 (en) | 2013-11-28 |
CA2873109A1 (en) | 2013-11-28 |
NZ701099A (en) | 2017-04-28 |
US9388392B2 (en) | 2016-07-12 |
CN104619835B (zh) | 2018-06-19 |
US20140051133A1 (en) | 2014-02-20 |
KR20150014953A (ko) | 2015-02-09 |
ZA201407713B (en) | 2016-05-25 |
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