ATE335823T1 - Verfahren zur biologischen herstellung von 1,3- propandiol - Google Patents

Verfahren zur biologischen herstellung von 1,3- propandiol

Info

Publication number
ATE335823T1
ATE335823T1 AT00955772T AT00955772T ATE335823T1 AT E335823 T1 ATE335823 T1 AT E335823T1 AT 00955772 T AT00955772 T AT 00955772T AT 00955772 T AT00955772 T AT 00955772T AT E335823 T1 ATE335823 T1 AT E335823T1
Authority
AT
Austria
Prior art keywords
propanediol
dehydratase
coli
present
improved process
Prior art date
Application number
AT00955772T
Other languages
English (en)
Inventor
Mark Emptage
Sharon Haynie
Lisa Laffend
Jeff Pucci
Greg Whited
Original Assignee
Du Pont
Genencor Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont, Genencor Int filed Critical Du Pont
Application granted granted Critical
Publication of ATE335823T1 publication Critical patent/ATE335823T1/de

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
AT00955772T 1999-08-18 2000-08-18 Verfahren zur biologischen herstellung von 1,3- propandiol ATE335823T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14953499P 1999-08-18 1999-08-18

Publications (1)

Publication Number Publication Date
ATE335823T1 true ATE335823T1 (de) 2006-09-15

Family

ID=22530731

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00955772T ATE335823T1 (de) 1999-08-18 2000-08-18 Verfahren zur biologischen herstellung von 1,3- propandiol

Country Status (13)

Country Link
US (5) US6514733B1 (de)
EP (1) EP1204755B1 (de)
JP (1) JP4716634B2 (de)
KR (1) KR100785997B1 (de)
CN (2) CN1298852C (de)
AT (1) ATE335823T1 (de)
BR (2) BR0013315B1 (de)
CA (2) CA2380616C (de)
DE (1) DE60029971T2 (de)
DK (1) DK1204755T3 (de)
HK (2) HK1044963B (de)
PT (1) PT1204755E (de)
WO (1) WO2001012833A2 (de)

Families Citing this family (120)

* Cited by examiner, † Cited by third party
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CN106906248A (zh) * 2017-03-28 2017-06-30 清华大学 一种利用重组微生物发酵生产1,3‑丙二醇的方法
CN107119003B (zh) * 2017-04-28 2020-04-24 中国科学院青岛生物能源与过程研究所 一种利用葡聚糖合成3-羟基丙酸的重组菌及其构建方法和应用
KR101994772B1 (ko) * 2017-11-09 2019-07-01 지에스칼텍스 주식회사 포도당으로부터 1,3-프로판디올를 생산하는 신규한 크렙시엘라 뉴모니아 균주 및 이를 이용한 1,3 프로판디올의 생산방법
CN108085288B (zh) * 2017-12-22 2021-03-09 广东清大智兴生物技术有限公司 一种利用重组微生物发酵生产1,3-丙二醇的方法
KR102053330B1 (ko) 2018-04-23 2019-12-06 한국과학기술연구원 글리세롤을 포함하는 미생물 발효용 조성물 및 이를 이용한 부티르산의 생산방법
KR102201720B1 (ko) * 2018-05-24 2021-01-12 한화솔루션 주식회사 1,3-pdo 생성능을 가지고 3-hp 생성능이 저해된 재조합 코리네박테리움 및 이를 이용한 1,3-pdo의 제조방법
CN109321610B (zh) * 2018-11-01 2022-11-04 上海交通大学 微生物发酵法高效制备2-氨基-1,3-丙二醇
CN110205277A (zh) * 2019-05-14 2019-09-06 河北科技师范学院 肠炎沙门菌glpK基因缺失的应用
CN111334459B (zh) * 2020-03-12 2022-11-25 中国科学院上海高等研究院 一种提高1,3-丙二醇产量的克雷伯氏工程菌构建方法及应用
CN114107145B (zh) * 2021-11-04 2024-05-07 清华大学 一种重组微生物及其在生产1,3-丙二醇中的应用

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