ATE329034T1 - Rekombinantes herstellungsverfahren für 1,3- propandiol - Google Patents

Rekombinantes herstellungsverfahren für 1,3- propandiol

Info

Publication number
ATE329034T1
ATE329034T1 AT97951433T AT97951433T ATE329034T1 AT E329034 T1 ATE329034 T1 AT E329034T1 AT 97951433 T AT97951433 T AT 97951433T AT 97951433 T AT97951433 T AT 97951433T AT E329034 T1 ATE329034 T1 AT E329034T1
Authority
AT
Austria
Prior art keywords
protein
seq
propanediol
gene encoding
production process
Prior art date
Application number
AT97951433T
Other languages
English (en)
Inventor
Nigel S Dunn-Coleman
Maria Diaz-Torres
Matthew W Chase
Donald Trimbur
Original Assignee
Genencor Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genencor Int filed Critical Genencor Int
Application granted granted Critical
Publication of ATE329034T1 publication Critical patent/ATE329034T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82Proteins from microorganisms
    • Y10S530/823Lower fungi, e.g. mold
    • Y10S530/824Yeasts

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT97951433T 1996-11-13 1997-11-13 Rekombinantes herstellungsverfahren für 1,3- propandiol ATE329034T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3060196P 1996-11-13 1996-11-13

Publications (1)

Publication Number Publication Date
ATE329034T1 true ATE329034T1 (de) 2006-06-15

Family

ID=21854996

Family Applications (2)

Application Number Title Priority Date Filing Date
AT97947395T ATE452979T1 (de) 1996-11-13 1997-11-10 Herstellungsverfahren von 1,3-propandiol durch rekombinante organismen
AT97951433T ATE329034T1 (de) 1996-11-13 1997-11-13 Rekombinantes herstellungsverfahren für 1,3- propandiol

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT97947395T ATE452979T1 (de) 1996-11-13 1997-11-10 Herstellungsverfahren von 1,3-propandiol durch rekombinante organismen

Country Status (18)

Country Link
US (3) US6013494A (de)
EP (2) EP0942989B1 (de)
JP (2) JP4327909B2 (de)
KR (1) KR100509310B1 (de)
CN (2) CN1236063C (de)
AT (2) ATE452979T1 (de)
AU (2) AU733534B2 (de)
BR (2) BR9712761B1 (de)
CA (2) CA2269088C (de)
DE (2) DE69739715D1 (de)
DK (1) DK0946732T3 (de)
ES (1) ES2336858T3 (de)
ID (1) ID21487A (de)
IL (2) IL129722A0 (de)
MY (1) MY131754A (de)
NZ (1) NZ335392A (de)
WO (2) WO1998021339A1 (de)
ZA (1) ZA9710194B (de)

Families Citing this family (168)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6428767B1 (en) * 1995-05-12 2002-08-06 E. I. Du Pont De Nemours And Company Method for identifying the source of carbon in 1,3-propanediol
US5686276A (en) 1995-05-12 1997-11-11 E. I. Du Pont De Nemours And Company Bioconversion of a fermentable carbon source to 1,3-propanediol by a single microorganism
WO1998021339A1 (en) * 1996-11-13 1998-05-22 E.I. Du Pont De Nemours And Company Method for the production of 1,3-propanediol by recombinant organisms
CN1174100C (zh) 1996-11-13 2004-11-03 纳幕尔杜邦公司 用重组生物体生产甘油的方法
WO1999028480A1 (en) 1997-12-02 1999-06-10 E.I. Du Pont De Nemours And Company Method for the production of glycerol by recombinant organisms
GB9806762D0 (en) * 1998-03-31 1998-05-27 Neutec Pharma Plc Treatment and diagnosis of staphylococcal infections
US6432686B1 (en) 1998-05-12 2002-08-13 E. I. Du Pont De Nemours And Company Method for the production of 1,3-propanediol by recombinant organisms comprising genes for vitamin B12 transport
US7074608B1 (en) 1998-05-12 2006-07-11 E. I. Du Pont De Nemours And Company Method for the production of 1,3-propanediol by recombinant organisms comprising genes for coenzyme B12 synthesis
WO2000008198A1 (en) 1998-08-04 2000-02-17 Metabolix, Inc. Polyhydroxyalkanoate production from polyols
US6468773B1 (en) * 1999-05-19 2002-10-22 Genencor International, Inc. Mutant 1,3-propandiol dehydrogenase
FR2796081B1 (fr) 1999-07-09 2003-09-26 Agronomique Inst Nat Rech Procede de preparation du 1,3-propanediol par un micro-organisme recombinant en l'absence de coenzyme b12 ou de l'un de ses precurseurs
EP1586647A1 (de) * 1999-08-18 2005-10-19 E.I. du Pont de Nemours and Company Verfahren zur biologischen Herstellung von 1,3-propanediol
CA2733616C (en) * 1999-08-18 2016-09-27 E.I. Du Pont De Nemours And Company Process for the biological production of 1,3-propanediol with high titer
ATE338139T1 (de) * 1999-08-30 2006-09-15 Wisconsin Alumni Res Found Herstellung von 3-hydroxypropionsäure in rekombinanten organismen
US6803218B1 (en) * 1999-09-24 2004-10-12 Genencor Intl., Inc. Enzymes which dehydrate glycerol
FR2800751B1 (fr) 1999-11-09 2003-08-29 Roquette Freres Procede de production de 1,3 propanediol par voie fermentaire
FR2801058B1 (fr) 1999-11-16 2002-01-18 Roquette Freres Procede de purification du 1,3-propanediol a partir d'un milieu de fermentation
EP1211234A3 (de) 2000-11-29 2003-11-26 Samsung Electronics Co., Ltd. Verfahren zur Herstellung von 1,3-Alkandiolen aus 3-Hydroxyestern
US6617478B2 (en) 2000-11-29 2003-09-09 Samsung Electronics Co., Ltd. Process for preparing a 1,3-alkandiol from 3-hydroxyester
US7309597B2 (en) * 2002-01-18 2007-12-18 Cargill, Incorporated Alanine 2,3-Aminomutase
EP1499709B1 (de) 2002-04-22 2012-01-04 E.I. Du Pont De Nemours And Company Promotor und plasmidsystem für die gentechnik
AU2003245878B2 (en) * 2002-05-08 2008-01-24 Basf Plant Science Gmbh Methods for increasing oil content in plants
DK1578943T3 (da) 2002-08-16 2012-01-09 Danisco Us Inc Nye variant-Hypocrea jecorina-CBH1-cellulaser
AU2003277276A1 (en) 2002-10-04 2004-05-04 Genencor International, Inc. Improved production of bacterial strains cross reference to related applications
MXPA05003382A (es) 2002-10-04 2005-06-22 Du Pont Proceso para la produccion biologica de 1,3-propanodiol con alto rendimiento.
US20040152159A1 (en) 2002-11-06 2004-08-05 Causey Thomas B. Materials and methods for the efficient production of acetate and other products
KR20050089970A (ko) 2002-12-16 2005-09-09 이 아이 듀폰 디 네모아 앤드 캄파니 반응 속도가 개선된 b12-의존성 데히드라타제
CA2517920C (en) * 2003-03-10 2012-12-18 Broin And Associates, Inc. Method for producing ethanol using raw starch
US20050233030A1 (en) 2004-03-10 2005-10-20 Broin And Associates, Inc. Methods and systems for producing ethanol using raw starch and fractionation
WO2004085611A2 (en) * 2003-03-21 2004-10-07 The Research Foundation Of State University Of New York Model for mutually exclusive domain folding molecular switch
CA2771875A1 (en) 2003-04-01 2005-01-06 Danisco Us Inc. Variant hypocrea jecorina cbh1
CA2522928C (en) * 2003-05-06 2013-09-24 E.I. Du Pont De Nemours And Company Purification of biologically-produced 1,3-propanediol
US7056439B2 (en) * 2003-05-06 2006-06-06 Tate & Lyle Ingredidents Americas, Inc. Process for producing 1, 3-propanediol
SI1685244T1 (sl) 2003-11-21 2012-06-29 Danisco Us Inc Ekspresija encimov, ki hidrolizirajo zrnat škrob, v Trichodermi in postopek za proizvajanje glukoze iz zrnatih škrobnih substratov
US20050239181A1 (en) * 2004-03-10 2005-10-27 Broin And Associates, Inc. Continuous process for producing ethanol using raw starch
WO2005093060A1 (ja) * 2004-03-26 2005-10-06 Nippon Shokubai Co., Ltd. 1,3−プロパンジオール及び/又は3−ヒドロキシプロピオン酸を製造する方法
CA2574280A1 (en) * 2004-07-30 2006-03-02 Cargill, Incorporated Alanine 2, 3 aminomutases
US8008056B2 (en) 2004-12-30 2011-08-30 Danisco Us Inc. Variant Hypocrea jecorina CBH2 cellulases
US7781191B2 (en) * 2005-04-12 2010-08-24 E. I. Du Pont De Nemours And Company Treatment of biomass to obtain a target chemical
US20070029252A1 (en) * 2005-04-12 2007-02-08 Dunson James B Jr System and process for biomass treatment
CN101160405B (zh) * 2005-04-12 2014-01-01 纳幕尔杜邦公司 处理生物质以获得目标化学物质
US20070037267A1 (en) * 2005-05-02 2007-02-15 Broin And Associates, Inc. Methods and systems for producing ethanol using raw starch and fractionation
US7524660B2 (en) 2005-05-05 2009-04-28 E.I. Du Pont De Nemours And Company Utilization of fructose in microbial production strains
CN1327001C (zh) * 2005-06-03 2007-07-18 清华大学 利用生物柴油副产物甘油生产1,3-丙二醇的方法
BRPI0611855A2 (pt) * 2005-06-16 2010-10-05 Wabash Technologies Inc conjunto de pedal com um mecanismo de histerese
CN100427605C (zh) * 2005-06-17 2008-10-22 清华大学 一种由粗淀粉原料生产1,3-丙二醇和2,3-丁二醇的方法
DE102005048818A1 (de) 2005-10-10 2007-04-12 Degussa Ag Mikrobiologische Herstellung von 3-Hydroxypropionsäure
US7919289B2 (en) * 2005-10-10 2011-04-05 Poet Research, Inc. Methods and systems for producing ethanol using raw starch and selecting plant material
US9303225B2 (en) 2005-10-26 2016-04-05 Butamax Advanced Biofuels Llc Method for the production of isobutanol by recombinant yeast
NZ593809A (en) 2005-10-26 2013-01-25 Butamax Tm Advanced Biofuels Fermentive production of four carbon alcohols
US8273558B2 (en) 2005-10-26 2012-09-25 Butamax(Tm) Advanced Biofuels Llc Fermentive production of four carbon alcohols
CN100392071C (zh) * 2005-12-05 2008-06-04 中国农业大学 产乳酸途径缺失的工程菌及其构建方法与应用
CN100463968C (zh) * 2006-01-27 2009-02-25 华侨大学 一种由生物催化转化甘油制备1,3-丙二醇和二羟基丙酮的方法
US20100074991A1 (en) * 2006-02-06 2010-03-25 Mutsaers Johanna Henrica Gerdi Novel oxidoreductases and uses thereof
US20070275139A1 (en) * 2006-02-10 2007-11-29 Melissa Joerger Food compositions comprising renewably-based, biodegradable1,3-propanediol
US20070241306A1 (en) 2006-02-10 2007-10-18 Ann Wehner Biodegradable compositions comprising renewably-based, biodegradable 1,3-propanediol
CN1935991B (zh) * 2006-06-21 2010-05-12 南宁中诺生物工程有限责任公司 产气荚膜梭菌甘油脱水酶基因及其1,3-丙二醇的生产方法
JP5130811B2 (ja) * 2006-07-19 2013-01-30 東レ株式会社 連続発酵による1,3−プロパンジオールの製造方法
DE102006039203B4 (de) 2006-08-22 2014-06-18 Evonik Degussa Gmbh Verfahren zur Herstellung von durch Kristallisation gereinigter Acrylsäure aus Hydroxypropionsäure sowie Vorrichtung dazu
MX2009004659A (es) * 2006-10-31 2009-05-22 Metabolic Explorer Sa Procedimiento para la produccion biologica de 1,3-propanodiol a partir de glicerina con un alto rendimiento.
WO2008052596A1 (en) * 2006-10-31 2008-05-08 Metabolic Explorer Process for the biological production of n-butanol with high yield
WO2008061187A1 (en) * 2006-11-15 2008-05-22 Dupont Tate & Lyle Bio Products Company, Llc Preservative compositions comprising renewably-based, biodegradable 1,3-propanediol
DE102007015583A1 (de) 2007-03-29 2008-10-02 Albert-Ludwigs-Universität Freiburg Ein Enzym zur Herstellung von Methylmalonyl-Coenzym A oder Ethylmalonyl-Coenzym A sowie dessen Verwendung
CN101130782B (zh) * 2007-07-23 2011-01-26 江南大学 以葡萄糖为底物产1,3-丙二醇重组酿酒酵母的构建方法
US20090053800A1 (en) * 2007-08-22 2009-02-26 Julie Friend Biomass Treatment Apparatus
US7807419B2 (en) * 2007-08-22 2010-10-05 E. I. Du Pont De Nemours And Company Process for concentrated biomass saccharification
US7819976B2 (en) * 2007-08-22 2010-10-26 E. I. Du Pont De Nemours And Company Biomass treatment method
US8445236B2 (en) * 2007-08-22 2013-05-21 Alliance For Sustainable Energy Llc Biomass pretreatment
DE102007041862A1 (de) 2007-09-03 2009-03-19 Evonik Degussa Gmbh Mikrobiologische Herstellung von Isoprenoiden
BRPI0816880A2 (pt) 2007-09-21 2015-09-08 Basf Plant Science Gmbh métodos para produzir uma planta com rendimento aumentado em comparação com uma planta do tipo selvagem correspondente, para produzir uma planta transgênica com rendimento aumentado em comparação com uma planta do tipo selvagem não transformada correspondente, para produzir uma composição agrícola, para identificar uma planta com um rendimento aumentado, e para aumentar o rendimento de uma população de plantas, molécula de ácido nucleico isolada, construção de ácido nucléico, vetor, processos para produzir um polipeptídeo, e para identificar um composto, polipeptídeo, anticorpo, núcleo de célula de planta, célula de planta, tecido de planta, material de propagação, pólen, progênie, material colhido ou planta, semente, parte de planta, planta transgênica, planta transgênica, núcleo de célula de planta transgênica, célula de planta transgênica, planta que compreende um ou mais de tais núcleos de célula de planta transgênica ou células de planta, progênie, semente ou pólen derivado de ou produzido por uma planta transgênica, composição, e, uso dos ácidos nucleicos.
CN101205541B (zh) * 2007-10-18 2010-12-08 北京化工大学 重组表达载体和用其转化的宿主细胞发酵甘油高产1,3-丙二醇的方法
US8048624B1 (en) 2007-12-04 2011-11-01 Opx Biotechnologies, Inc. Compositions and methods for 3-hydroxypropionate bio-production from biomass
DE102007060705A1 (de) 2007-12-17 2009-06-18 Evonik Degussa Gmbh ω-Aminocarbonsäuren oder ihre Lactame, herstellende, rekombinante Zellen
CN101918539A (zh) 2007-12-17 2010-12-15 阿姆斯特丹大学 包含发酵基因卡盒的自养生物进行光驱动的co2还原生成有机化合物以用作燃料或用作工业半成品
KR20110020243A (ko) 2008-06-06 2011-03-02 다니스코 유에스 인크. 비-셀룰로오스 물질에 대해 감소된 친화성을 갖는 셀룰라아제 변이체를 포함하는 조성물 및 방법
DE102008002715A1 (de) 2008-06-27 2009-12-31 Evonik Röhm Gmbh 2-Hydroxyisobuttersäure produzierende rekombinante Zelle
DE102008041299A1 (de) 2008-08-18 2010-02-25 Evonik Degussa Gmbh Neuartiges, universell einsetzbares addiction-System
WO2010031083A2 (en) * 2008-09-15 2010-03-18 Opx Biotechnologies, Inc. Methods, systems and compositions related to reduction of conversions of microbially produced 3-hydroxypropionic acid (3-hp) to aldehyde metabolites
EP2364358B1 (de) 2008-12-10 2013-03-06 Direvo Industrial Biotechnology GmbH Polypeptide mit cellobiohydrolase-ii-aktivität
US20100159521A1 (en) * 2008-12-19 2010-06-24 E. I. Du Pont De Nemours And Company Ozone treatment of biomass to enhance enzymatic saccharification
WO2010102060A2 (en) * 2009-03-03 2010-09-10 Poet Research, Inc. System for pre-treatment of biomass for the production of ethanol
US8450094B1 (en) 2009-03-03 2013-05-28 Poet Research, Inc. System for management of yeast to facilitate the production of ethanol
HUE025623T2 (en) 2009-03-03 2016-04-28 Poet Res Inc A method of fermenting biomass for ethanol production
US9068206B1 (en) 2009-03-03 2015-06-30 Poet Research, Inc. System for treatment of biomass to facilitate the production of ethanol
KR20120062643A (ko) 2009-06-03 2012-06-14 다니스코 유에스 인크. 향상된 발현, 활성 및/또는 안정성을 갖는 셀룰라아제 변이체, 및 이의 용도
BR112012006801A2 (pt) 2009-09-27 2018-04-10 Opx Biotechnologies Inc método para produção de ácido 3-hidroxipropiônico e outros produtos
US8809027B1 (en) 2009-09-27 2014-08-19 Opx Biotechnologies, Inc. Genetically modified organisms for increased microbial production of 3-hydroxypropionic acid involving an oxaloacetate alpha-decarboxylase
US8852903B2 (en) 2009-10-23 2014-10-07 E I Du Pont De Nemours And Company Co-metabolism of fructose and glucose in microbial production strains
DE102009046623A1 (de) 2009-11-11 2011-05-12 Evonik Röhm Gmbh Verwendung eines zu einem MeaB-Protein homologen Proteins zur Erhöhung der enzymatischen Aktivität einer 3-Hydroxycarbonsäure-CoA-Mutase
DE102010014680A1 (de) 2009-11-18 2011-08-18 Evonik Degussa GmbH, 45128 Zellen, Nukleinsäuren, Enzyme und deren Verwendung sowie Verfahren zur Herstellung von Sophorolipiden
WO2011063363A2 (en) * 2009-11-20 2011-05-26 Opx Biotechnologies, Inc. Production of an organic acid and/or related chemicals
US20110136190A1 (en) 2009-12-04 2011-06-09 E. I. Du Pont De Nemours And Company Recombinant bacteria for producing glycerol and glycerol-derived products from sucrose
US8034592B2 (en) * 2009-12-10 2011-10-11 The Curators Of The University Of Missouri Fossil fuel-free process of lignocellulosic pretreatment with biological hydrogen production
BR112012020299A8 (pt) 2010-02-11 2017-10-03 Metabolix Inc Processo para produção de gama-butirolactona
KR101144235B1 (ko) * 2010-02-25 2012-05-10 한국과학기술연구원 바이오에탄올 폐발효액을 이용한 부탄올의 제조방법
WO2011132511A1 (ja) * 2010-04-19 2011-10-27 サッポロビール株式会社 新規微生物並びにそれを用いた水素製造方法、1,3-プロパンジオール製造方法及びバイオディーゼル廃液の処理方法
US8721794B2 (en) 2010-04-28 2014-05-13 E I Du Pont De Nemours And Company Production of high solids syrup from lignocellulosic biomass hydrolysate fermentation broth
US8906235B2 (en) 2010-04-28 2014-12-09 E I Du Pont De Nemours And Company Process for liquid/solid separation of lignocellulosic biomass hydrolysate fermentation broth
KR101220499B1 (ko) * 2010-05-25 2013-01-10 한국생명공학연구원 글리세롤로부터 3-하이드록시프로피온산을 고수율로 제조하는 방법
NZ605093A (en) 2010-07-12 2014-05-30 Univ Gent Metabolically engineered organisms for the production of added value bio-products
DE102010032484A1 (de) 2010-07-28 2012-02-02 Evonik Goldschmidt Gmbh Zellen und Verfahren zur Herstellung von Rhamnolipiden
US20130224804A1 (en) * 2010-09-01 2013-08-29 Eric Knight Expression of steady state metabolic pathways
US8129170B1 (en) 2010-12-06 2012-03-06 E.I. Du Pont De Nemours And Company Recombinant bacteria having the ability to metabolize sucrose
BR112013025753A8 (pt) * 2011-04-05 2018-06-12 Lallemand Hungary Liquidity Man Llc Métodos para aprimoramento do rendimento de produto e produção em um micro-organismo através da adição de aceptores de elétrons alternativos
JP5941531B2 (ja) 2011-04-13 2016-06-29 イーエルシー マネージメント エルエルシー パーソナルケア組成物に適した温和なアニオン界面活性剤
WO2012142170A2 (en) 2011-04-13 2012-10-18 Elc Management Llc Conditioning agents for personal care compositions
FR2976949B1 (fr) * 2011-06-21 2015-08-28 Sanofi Sa Procede de preparation de levures genetiquement transformees capables de produire une molecule d'interet a haut titre
US8785697B2 (en) 2011-06-24 2014-07-22 Eastman Chemical Company Nickel modified catalyst for the production of hydroxy ether hydrocarbons by vapor phase hydrogenolysis of cyclic acetals and ketals
US8969598B2 (en) 2011-06-24 2015-03-03 Eastman Chemical Company Production of cyclic acetals or ketals using liquid-phase acid catalysts
US9000229B2 (en) 2011-06-24 2015-04-07 Eastman Chemical Company Production of hydroxy ether hydrocarbons by vapor phase hydrogenolysis of cyclic acetals and ketals
US9056313B2 (en) 2011-06-24 2015-06-16 Eastman Chemical Company Catalysts for the production of hydroxy ether hydrocarbons by vapor phase hydrogenolysis of cyclic acetals and ketals
US8829206B2 (en) 2011-06-24 2014-09-09 Eastman Chemical Company Production of cyclic acetals or ketals using solid acid catalysts
US8829207B2 (en) 2011-06-24 2014-09-09 Eastman Chemical Company Production of cyclic acetals by reactive distillation
US9388105B2 (en) 2011-06-24 2016-07-12 Eastman Chemical Company Production of hydroxy ether hydrocarbons by liquid phase hydrogenolysis of cyclic acetals or cyclic ketals
EP2540834A1 (de) 2011-06-29 2013-01-02 Metabolic Explorer Verfahren zur Herstellung von 1,3-Propandiol
JP2013013353A (ja) * 2011-07-01 2013-01-24 Daicel Corp 1,3−プロパンジオールの製造方法
JP2013070675A (ja) * 2011-09-28 2013-04-22 Daicel Corp アルキルジオールを産生する組換え菌の培養方法
DE102012201360A1 (de) 2012-01-31 2013-08-01 Evonik Industries Ag Zellen und Verfahren zur Herstellung von Rhamnolipiden
US9017961B2 (en) 2012-03-05 2015-04-28 E.I. Du Pont De Nemours And Company Recombinant bacteria comprising novel sucrose transporters
US8686114B2 (en) 2012-03-05 2014-04-01 E I Du Pont De Nemours And Company Variant sucrose transporter polypeptides
CN102634543A (zh) * 2012-05-04 2012-08-15 杭玉玲 微生物发酵生产1,3-丙二醇的方法
CN104350034B (zh) 2012-06-08 2018-07-31 Cj 第一制糖株式会社 可再生丙烯酸生产和自其制备的产物
MX2015001780A (es) 2012-08-10 2015-09-28 Opx Biotechnologies Inc Microorganismos y métodos para la producción de ácidos grasos y productos derivados de ácidos grasos.
KR101437040B1 (ko) * 2012-08-17 2014-09-02 삼성전자 주식회사 삼투압 보호제 첨가에 의한 1,3-프로판디올 생산방법 및 생산용 배지
IN2015DN01365A (de) * 2012-08-28 2015-07-03 Lanzatech New Zealand Ltd
EP2931887A1 (de) 2012-12-12 2015-10-21 Danisco US Inc. Varianten von cellobiohydrolasen
US20140178954A1 (en) 2012-12-20 2014-06-26 E I Du Pont De Nemours And Company Expression of xylose isomerase activity in yeast
WO2014127053A2 (en) 2013-02-13 2014-08-21 Metabolix, Inc. Process for ultra pure chemical production from biobased raw starting materials
US8669076B1 (en) 2013-03-11 2014-03-11 E I Du Pont De Nemours And Company Cow rumen xylose isomerases active in yeast cells
US9187743B2 (en) 2013-03-11 2015-11-17 E I Du Pont De Nemours And Company Bacterial xylose isomerases active in yeast cells
US20140273105A1 (en) 2013-03-12 2014-09-18 E I Du Pont De Nemours And Company Gradient pretreatment of lignocellulosic biomass
EP2970863B1 (de) * 2013-03-14 2019-04-24 E. I. du Pont de Nemours and Company Glycerol-3-phosphat-dehydrogenase zur butanolherstellung
US10584860B2 (en) * 2013-03-14 2020-03-10 Ideal Industries, Llc Linear light fixture with interchangeable light engine unit
US20140315258A1 (en) 2013-03-14 2014-10-23 Abengoa Bioenergy New Technologies, Llc Methods for converting cellulosic waste to bioproducts
CA2905602A1 (en) 2013-03-15 2014-09-18 Sarah M. Hoyt Flash evaporation for product purification and recovery
WO2014146026A1 (en) 2013-03-15 2014-09-18 Opx Biotechnologies, Inc. Bioproduction of chemicals
CN106795483A (zh) 2013-07-19 2017-05-31 嘉吉公司 用于生产脂肪酸和脂肪酸衍生产物的微生物及方法
US11408013B2 (en) 2013-07-19 2022-08-09 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
US10035749B2 (en) 2013-09-03 2018-07-31 Myriant Corporation Process for manufacturing acrylic acid, acrylonitrile and 1,4-butanediol from 1,3-propanediol
CN105531373A (zh) * 2013-09-06 2016-04-27 密苏里州立大学校董 盐碱条件下甘油向1,3-丙二醇的转化
US10227623B2 (en) 2013-11-24 2019-03-12 E I Du Pont De Nemours And Company High force and high stress destructuring of cellulosic biomass
KR101532736B1 (ko) 2014-02-24 2015-07-09 한국생명공학연구원 2,3-부탄디올 합성 유전자가 결실된 미생물 변이체를 이용한 1,3-프로판디올의 제조방법
FR3015186A1 (fr) * 2014-03-11 2015-06-26 Antoine Piccirilli Utilisation d'une composition renfermant du 1,3-propanediol comme e-liquide
EP2949214A1 (de) 2014-05-26 2015-12-02 Evonik Degussa GmbH Verfahren zur Herstellung von Rhamnolipiden
WO2016007350A1 (en) 2014-07-09 2016-01-14 Danisco Us Inc. Preconditioning of lignocellulosic biomass
EP2993228B1 (de) 2014-09-02 2019-10-09 Cargill, Incorporated Herstellung von fettsäureestern
EP3056561A1 (de) 2015-02-16 2016-08-17 Evonik Degussa GmbH Mikroorganismen mit reduzierter Enzymaktivität
WO2016131801A1 (en) 2015-02-19 2016-08-25 Evonik Degussa Gmbh Rhamnolipid synthesis
EP3288012B1 (de) * 2015-04-20 2022-04-27 Pi-Crystal Incorporation Verfahren zur herstellung einer aktivmatrixarrayvorrichtung und damit hergestellte aktivmatrixarrayvorrichtung
CN104774879B (zh) * 2015-04-29 2017-10-20 大连理工大学 一种混菌发酵甘油生产1,3‑丙二醇的方法
EP3330375A1 (de) 2015-07-29 2018-06-06 Abengoa Bioenergía Nuevas Tecnologías, S. A. Expression von rekombinanten beta-xylosidaseenzymen
US9968531B2 (en) 2015-08-05 2018-05-15 Dupont Tate & Lyle Bio Products Company, Llc Deodorants containing 1,3-propanediol
EP3192866A1 (de) 2016-01-15 2017-07-19 CIC nanoGUNE - Asociación Centro de Investigación Cooperativa en Nanociencias Endocellulasen und verwendungen davon
BR112018070645A2 (pt) 2016-04-08 2019-02-05 Du Pont células de levedura recombinante, métodos para produzir uma célula de levedura e método para produzir um composto alvo
US11685905B2 (en) 2016-10-24 2023-06-27 Evonik Operations Gmbh Rhamnolipid-producing cell having reduced glucose dehydrogenase activity
JP2019532088A (ja) 2016-10-24 2019-11-07 エボニック デグサ ゲーエムベーハーEvonik Degussa GmbH 代替グルコーストランスポーターを使用してラムノリピドを製造するための細胞および方法
WO2018144701A2 (en) 2017-02-02 2018-08-09 Cargill Incorporated Genetically modified cells that produce c6-c10 fatty acid derivatives
EP3502126A1 (de) 2017-12-19 2019-06-26 CIC nanoGUNE - Asociación Centro de Investigación Cooperativa en Nanociencias Anzestrale cellulasen und verwendungen davon
KR102103408B1 (ko) * 2018-01-16 2020-04-23 한국과학기술원 1,3-프로판디올 생성능을 가지는 변이미생물 및 이를 이용한 1,3-pdo의 제조방법
WO2019152755A1 (en) * 2018-02-01 2019-08-08 Invista North America S.A.R.L. Methods and materials for the biosynthesis of beta hydroxy acids and/or derivatives thereof and/or compounds related thereto
KR20200119282A (ko) 2018-02-09 2020-10-19 에보닉 오퍼레이션스 게엠베하 글루코리피드를 포함하는 혼합 조성물
CN111386345B (zh) * 2018-10-30 2023-05-16 绿色地球研究所株式会社 1,3-丙二醇的制造方法
CN109370969B (zh) * 2018-11-12 2020-09-04 江南大学 一种重组克雷伯氏杆菌在制备1,3-丙二醇中的应用
CN109337852B (zh) * 2018-11-12 2020-09-04 江南大学 一种重组克雷伯氏杆菌在生产1,3-丙二醇中的应用
CN109750011B (zh) * 2019-02-20 2022-05-10 中国科学院天津工业生物技术研究所 一种甘露糖6-磷酸磷酸酶及甘露糖生物制备方法
CN112625994B (zh) * 2021-01-05 2022-04-15 清华大学 一种重组需钠弧菌及其应用
CN114806981B (zh) * 2021-01-18 2023-05-23 中国科学院上海高等研究院 克雷伯氏菌工程菌在生产1,3-丙二醇中的应用
CN114107145B (zh) * 2021-11-04 2024-05-07 清华大学 一种重组微生物及其在生产1,3-丙二醇中的应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3634764A1 (de) 1986-10-11 1988-04-14 Mueller Haidmann Roland Dipl I Aus platten zusammengesetzte decke
DE3734764A1 (de) * 1987-10-14 1989-05-03 Huels Chemische Werke Ag Verfahren zur herstellung von propandiol-(1,3)
EP0373230B1 (de) * 1988-12-12 1993-02-17 Unilever N.V. Verfahren zur mikrobiologischen Herstellung von 1,3-Propandiol aus Glycerin
US5686276A (en) 1995-05-12 1997-11-11 E. I. Du Pont De Nemours And Company Bioconversion of a fermentable carbon source to 1,3-propanediol by a single microorganism
US5599689A (en) * 1995-05-12 1997-02-04 E. I. Du Pont De Nemours And Company Process for making 1,3-propanediol from carbohydrates using mixed microbial cultures
US5633362A (en) * 1995-05-12 1997-05-27 E. I. Du Pont De Nemours And Company Production of 1,3-propanediol from glycerol by recombinant bacteria expressing recombinant diol dehydratase
WO1998021339A1 (en) * 1996-11-13 1998-05-22 E.I. Du Pont De Nemours And Company Method for the production of 1,3-propanediol by recombinant organisms

Also Published As

Publication number Publication date
KR100509310B1 (ko) 2005-08-22
EP0946732A2 (de) 1999-10-06
JP2001503636A (ja) 2001-03-21
IL129722A (en) 2008-07-08
CN1198935C (zh) 2005-04-27
MY131754A (en) 2007-08-30
EP0946732B1 (de) 2006-06-07
ZA9710194B (en) 1999-05-12
JP2001504338A (ja) 2001-04-03
AU733534B2 (en) 2001-05-17
BR9712761B1 (pt) 2010-02-23
BR9714313B1 (pt) 2014-10-21
JP4327909B2 (ja) 2009-09-09
US6136576A (en) 2000-10-24
CN1236063C (zh) 2006-01-11
US20030022323A1 (en) 2003-01-30
EP0942989B1 (de) 2009-12-23
DE69736070D1 (de) 2006-07-20
NZ335392A (en) 2000-10-27
DE69739715D1 (de) 2010-02-04
US6013494A (en) 2000-01-11
AU5248498A (en) 1998-06-03
AU735080B2 (en) 2001-06-28
KR20000053213A (ko) 2000-08-25
WO1998021339A1 (en) 1998-05-22
CA2269088A1 (en) 1998-05-22
CA2269088C (en) 2009-07-28
CA2270906A1 (en) 1998-05-22
WO1998021341A3 (en) 1998-06-25
DE69736070T2 (de) 2006-12-21
ES2336858T3 (es) 2010-04-16
ATE452979T1 (de) 2010-01-15
IL129722A0 (en) 2000-02-29
BR9712761A (pt) 1999-10-26
EP0942989A1 (de) 1999-09-22
US6953684B2 (en) 2005-10-11
BR9714313A (pt) 2001-09-18
CN1244217A (zh) 2000-02-09
AU5507698A (en) 1998-06-03
DK0946732T3 (da) 2006-10-09
WO1998021341A2 (en) 1998-05-22
ID21487A (id) 1999-06-17
CN1239511A (zh) 1999-12-22

Similar Documents

Publication Publication Date Title
ATE329034T1 (de) Rekombinantes herstellungsverfahren für 1,3- propandiol
DE69702720T2 (de) Peniophora phytase
DE60029971D1 (de) Verfahren zur biologischen herstellung von 1,3-propandiol
AU6414196A (en) A modified enzyme with lipolytic activity
IT1141977B (it) Polipeptide prodotto microbiologicamente con la sequenza di aminoacidi dell'interferone umano,dna e plasmidi che codificano per questa sequenza,microorganismi che contengono queste informazioni genetiche e processo per la loro preparazione
Gatlin The information content of DNA. II
ATE239036T1 (de) Rekombinantes core-streptavidin
NZ512835A (en) Genes identified as required for proliferation in escherichia coli
EP1380648A3 (de) Rekombinante DNAse B aus Streptococcus pyogenes
KR920004570A (ko) 사람 mk 단백질을 암호하는 유전자, 이를 포함하는 발현 벡터 및 숙주 세포, mk단백질의 생산 방법 및 사용방법
ATE371741T1 (de) Systeme zur massenherstellung von proteinen oder peptiden durch mikroorganismen der gattung humicola
BR8108074A (pt) Sequencia de dna,plasmidio recombinante,ligadores de dna,cultura bacterial e processo para produzir taumatina
ATE334195T1 (de) Proteine mit zellulase-aktivitäten und prozess für ihre herstellung
DE50115438D1 (de) Für das dapC-Gen kodierende Nukleotidsequenzen und Verfahren zur Herstellung von L-Lysin
DE60330579D1 (de) Mikrobielle trypsinvarianten mit chymotrypsinaktivität und diese codierende nukleinsäuren
AU2430588A (en) Mutant acidic fibroblast growth factor
CO4480058A1 (es) Genes codificantes y procedimiento de expresion de una nueva enzima: ftalil amidasa
CA2384122A1 (en) Cyclic depsipeptide synthetase and gene thereof, and mass production system for cyclic depsipeptide
DE69729010D1 (de) Produktion des proteins ingap mit hoher expressionsrate
SE8502430D0 (sv) A cdna molecule coding for the expression of an interferon alfa type polypeptide, a bacterial or cellular host transformed with such molecule and a polypeptide showing interferon activity prepared by such host
TW200700554A (en) Saponin-decomposing enzyme, gene thereof and large-scale production system for producing soyasapogenol b
EP0828004A3 (de) Protein-disulfidisomerase-Gen eines methylotrophen Hefestammes
CA2192260A1 (en) Dna fragment encoding a protein involved in fatty aldehyde decarbonylase activity, recombinant molecules comprising said fragment and a method for obtaining transformed bacterial cells and plants
CA2407059A1 (en) Novel (r)-2-hydroxy-3-phenylpropionic acid (d-phenyllactic acid) dehydrogenase and gene encoding the same
ATE398681T1 (de) Nukleotidsequenzen die für das mene-gen kodieren

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties