ATE338139T1 - Herstellung von 3-hydroxypropionsäure in rekombinanten organismen - Google Patents

Herstellung von 3-hydroxypropionsäure in rekombinanten organismen

Info

Publication number
ATE338139T1
ATE338139T1 AT00959652T AT00959652T ATE338139T1 AT E338139 T1 ATE338139 T1 AT E338139T1 AT 00959652 T AT00959652 T AT 00959652T AT 00959652 T AT00959652 T AT 00959652T AT E338139 T1 ATE338139 T1 AT E338139T1
Authority
AT
Austria
Prior art keywords
production
hydroxypropionic acid
recombinant organisms
bacterial host
glycerol
Prior art date
Application number
AT00959652T
Other languages
English (en)
Inventor
Patrick F Suthers
Douglas C Cameron
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Application granted granted Critical
Publication of ATE338139T1 publication Critical patent/ATE338139T1/de

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0008Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42Hydroxy-carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y402/00Carbon-oxygen lyases (4.2)
    • C12Y402/01Hydro-lyases (4.2.1)
    • C12Y402/0103Glycerol dehydratase (4.2.1.30)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT00959652T 1999-08-30 2000-08-30 Herstellung von 3-hydroxypropionsäure in rekombinanten organismen ATE338139T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15144099P 1999-08-30 1999-08-30

Publications (1)

Publication Number Publication Date
ATE338139T1 true ATE338139T1 (de) 2006-09-15

Family

ID=22538777

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00959652T ATE338139T1 (de) 1999-08-30 2000-08-30 Herstellung von 3-hydroxypropionsäure in rekombinanten organismen

Country Status (6)

Country Link
EP (1) EP1124979B1 (de)
AT (1) ATE338139T1 (de)
AU (1) AU7093600A (de)
BR (1) BR0008355A (de)
DE (1) DE60030403D1 (de)
WO (1) WO2001016346A1 (de)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA03004324A (es) 2000-11-20 2004-01-26 Cargill Inc Acido 3-hidroxipropionico y otros compuestos organicos.
MXPA04006894A (es) 2002-01-18 2004-10-15 Cargill Inc Alanina 2,3 - aminomutasa.
AU2003207708A1 (en) * 2002-02-20 2003-09-09 Sirna Therapeutics, Inc. Rna interference mediated inhibition of map kinase genes
ATE413456T1 (de) * 2002-03-13 2008-11-15 Evonik Degussa Gmbh Verfahren zur herstellung von l-aminosäuren unter verwendung von stämmen der familie enterobacteriaceae
DE10210960A1 (de) * 2002-03-13 2003-09-25 Degussa Verfahren zur fermentativen Hestellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae
WO2003082795A2 (en) * 2002-03-25 2003-10-09 Cargill, Incorporated METHODS OF MANUFACTURING DERIVATIVES OF β-HYDROXYCARBOXYLIC ACIDS
DK1706457T3 (da) 2003-12-04 2012-05-21 Novozymes As Fremstilling af 3-hydroxypropionsyre ved anvendelse af beta-alanin/pyruvataminotransferase
EP2292749A3 (de) 2004-07-30 2011-12-21 Novozymes A/S Alanine 2, 3 Aminomutasen
WO2006047589A2 (en) 2004-10-25 2006-05-04 Codexis, Inc. Improved alanine 2,3-aminomutases and related polynucleotides
TWI529181B (zh) * 2005-02-28 2016-04-11 贏創德固賽有限責任公司 以可更新原料為基之吸水聚合物結構及其生產的方法
JP2007082476A (ja) * 2005-09-22 2007-04-05 Nippon Shokubai Co Ltd グリセリンから3−ヒドロキシプロピオン酸を製造する方法
DE102005048818A1 (de) 2005-10-10 2007-04-12 Degussa Ag Mikrobiologische Herstellung von 3-Hydroxypropionsäure
US8030051B2 (en) 2005-10-14 2011-10-04 Codexis, Inc. Alanine 2,3-aminomutases and related polynucleotides
DE102006039203B4 (de) 2006-08-22 2014-06-18 Evonik Degussa Gmbh Verfahren zur Herstellung von durch Kristallisation gereinigter Acrylsäure aus Hydroxypropionsäure sowie Vorrichtung dazu
DE102007015583A1 (de) 2007-03-29 2008-10-02 Albert-Ludwigs-Universität Freiburg Ein Enzym zur Herstellung von Methylmalonyl-Coenzym A oder Ethylmalonyl-Coenzym A sowie dessen Verwendung
US8048624B1 (en) 2007-12-04 2011-11-01 Opx Biotechnologies, Inc. Compositions and methods for 3-hydroxypropionate bio-production from biomass
US8691553B2 (en) 2008-01-22 2014-04-08 Genomatica, Inc. Methods and organisms for utilizing synthesis gas or other gaseous carbon sources and methanol
JP5755884B2 (ja) 2008-03-05 2015-07-29 ジェノマティカ, インコーポレイテッド 第一級アルコールを産生する生物
US8241877B2 (en) 2008-05-01 2012-08-14 Genomatica, Inc. Microorganisms for the production of methacrylic acid
MY155117A (en) 2008-07-30 2015-09-15 Mitsui Chemicals Inc Polyester polyol, composition for polyurethane, composition for polyurethane foam, polyurethane resin, and polyurethane foam
CN106119113A (zh) 2009-04-30 2016-11-16 基因组股份公司 用于生产 1,3‑丁二醇的生物
BRPI1013505A2 (pt) 2009-04-30 2018-02-14 Genomatica Inc organismos para a produção de isopropanol, n-butanol, e isobutanol
WO2010131603A1 (ja) 2009-05-15 2010-11-18 株式会社日本触媒 (メタ)アクリル酸の製造方法および晶析システム
US8637701B2 (en) 2009-05-15 2014-01-28 Nippon Shokubai Co., Ltd. Method for producing (meth) acrylic acid
EP2431351B1 (de) 2009-05-15 2017-09-20 Nippon Shokubai Co., Ltd. Herstellungsverfahren für (meth)acrylsäure
EP2462221B1 (de) 2009-08-05 2017-02-22 Genomatica, Inc. Aus muconsäureproduzierenden mikroorganismen gewonnene halbsynthetische terephthalsäure
BR112012006801A2 (pt) 2009-09-27 2018-04-10 Opx Biotechnologies Inc método para produção de ácido 3-hidroxipropiônico e outros produtos
US8809027B1 (en) 2009-09-27 2014-08-19 Opx Biotechnologies, Inc. Genetically modified organisms for increased microbial production of 3-hydroxypropionic acid involving an oxaloacetate alpha-decarboxylase
US20110097767A1 (en) 2009-10-23 2011-04-28 Priti Pharkya Microorganisms for the production of aniline
WO2011052819A1 (ko) * 2009-10-29 2011-05-05 한국생명공학연구원 글리세롤로부터 3-하이드록시프로피온산을 생산하는 새로운 방법
MX2012008738A (es) 2010-01-29 2012-08-31 Genomatica Inc Microorganismos y metodos para la biosintesis de p-toluato y tereftalato.
US9023636B2 (en) 2010-04-30 2015-05-05 Genomatica, Inc. Microorganisms and methods for the biosynthesis of propylene
EP2588598B1 (de) 2010-07-02 2016-03-09 Metabolic Explorer Verfahren zur herstellung von hydroxysäuren
EP3312284A3 (de) 2010-07-26 2018-05-30 Genomatica, Inc. Mikroorganismen und verfahren zur biosynthese von aromaten, 2,4-pentadienoat und 1,3-butadien
CA2807561C (en) 2010-08-06 2022-04-12 Mascoma Corporation Production of malonyl-coa derived products via anaerobic pathways
JP6061862B2 (ja) 2010-11-22 2017-01-18 カーギル,インコーポレイティド 3‐ヒドロキシプロピオン酸生産用の組成物及び方法
WO2012091114A1 (ja) 2010-12-28 2012-07-05 株式会社日本触媒 アクリル酸および/またはそのエステルおよびその重合体の製法
BR112014007647A2 (pt) 2011-09-30 2017-04-18 Novozymes As “variante de 3-hpdh, polipeptídeo tendo atividade de 3-hpdh, polinucleotídeo isolado, célula hospedeira microbiana transgênica, e, método para produzir 3-hp
KR101494386B1 (ko) * 2011-12-07 2015-02-23 삼성전자주식회사 3-하이드록시프로피온알데히드 및/또는 3-하이드록시프로피온산을 생산하는 재조합 미생물 및 이를 이용한 3-하이드록시프로피온알데히드 및/또는 3-하이드록시프로피온산의 생산방법
WO2013085321A1 (ko) * 2011-12-07 2013-06-13 삼성전자주식회사 3-하이드록시프로피온알데히드 및/또는 3-하이드록시프로피온산을 생산하는 재조합 미생물 및 이를 이용한 3-하이드록시프로피온알데히드 및/또는 3-하이드록시프로피온산의 생산방법
EP2868648B1 (de) 2012-06-27 2019-02-20 Nippon Shokubai Co., Ltd. (meth)acrylsäure-herstellungsverfahren und harzherstellungsverfahren für ein hydrophiles harz
SG11201501013PA (en) 2012-08-10 2015-04-29 Opx Biotechnologies Inc Microorganisms and methods for the production of fatty acids and fatty acid derived products
JP2015536669A (ja) 2012-11-30 2015-12-24 ノボザイムス,インコーポレイティド 組換え酵母による3−ヒドロキシプロピオン酸の生産
US9334220B2 (en) 2013-01-08 2016-05-10 Shell Oil Company Production of acrylic acid
US20150119601A1 (en) 2013-03-15 2015-04-30 Opx Biotechnologies, Inc. Monofunctional mcr + 3-hp dehydrogenase
EP2976141A4 (de) 2013-03-15 2016-10-05 Cargill Inc Blitzverdampfung für produktionsreinigung und rückgewinnung
US10077455B2 (en) 2013-06-14 2018-09-18 Technical University Of Denmark 3HP tolerance
BR112016001026A2 (pt) 2013-07-19 2017-10-24 Cargill Inc organismo geneticamente modificado
US11408013B2 (en) 2013-07-19 2022-08-09 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
US9944586B2 (en) 2013-10-17 2018-04-17 Cargill, Incorporated Methods for producing alkyl hydroxyalkanoates
EP2993228B1 (de) 2014-09-02 2019-10-09 Cargill, Incorporated Herstellung von fettsäureestern
US10239819B2 (en) 2014-10-17 2019-03-26 Cargill, Incorporated Methods for producing an ester of an alpha, beta-unsaturated carboxylic acid
US10358664B2 (en) 2015-02-27 2019-07-23 Novozymes A/S Mutant host cells for the production of 3-hydroxypropionic acid
US20200262778A1 (en) 2016-09-27 2020-08-20 Shell Oil Company Process for production of allyl alcohol
CN110494566A (zh) 2017-02-02 2019-11-22 嘉吉公司 产生c6-c10脂肪酸衍生物的经遗传修饰的细胞
MX2020007582A (es) 2018-01-16 2020-09-03 Dicerna Pharmaceuticals Inc Composiciones y metodos para inhibir la expresion de aldehido deshidrogenasa mitocondrial 2 (aldh2).
JP2023531938A (ja) * 2020-07-31 2023-07-26 エルジー・ケム・リミテッド 3-ヒドロキシプロピオン酸の2段階製造方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69739715D1 (de) * 1996-11-13 2010-02-04 Du Pont Herstellungsverfahren von 1,3-propandiol durch rekombinante organismen
EP1975236B1 (de) * 1998-08-04 2015-05-06 Metabolix, Inc. Herstellung von Polyhydroxyalkanoat aus Polyolen

Also Published As

Publication number Publication date
EP1124979A4 (de) 2002-08-28
EP1124979A1 (de) 2001-08-22
AU7093600A (en) 2001-03-26
BR0008355A (pt) 2002-07-16
DE60030403D1 (de) 2006-10-12
WO2001016346A1 (en) 2001-03-08
EP1124979B1 (de) 2006-08-30

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