DE60030403D1 - Herstellung von 3-hydroxypropionsäure in rekombinanten organismen - Google Patents

Herstellung von 3-hydroxypropionsäure in rekombinanten organismen

Info

Publication number
DE60030403D1
DE60030403D1 DE60030403T DE60030403T DE60030403D1 DE 60030403 D1 DE60030403 D1 DE 60030403D1 DE 60030403 T DE60030403 T DE 60030403T DE 60030403 T DE60030403 T DE 60030403T DE 60030403 D1 DE60030403 D1 DE 60030403D1
Authority
DE
Germany
Prior art keywords
hydroxypropionic acid
preparation
recombinant organisms
production
bacterial host
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60030403T
Other languages
English (en)
Inventor
F Suthers
C Cameron
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wisconsin Alumni Research Foundation
Original Assignee
Wisconsin Alumni Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Research Foundation filed Critical Wisconsin Alumni Research Foundation
Application granted granted Critical
Publication of DE60030403D1 publication Critical patent/DE60030403D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/01—Hydro-lyases (4.2.1)
    • C12Y402/0103—Glycerol dehydratase (4.2.1.30)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE60030403T 1999-08-30 2000-08-30 Herstellung von 3-hydroxypropionsäure in rekombinanten organismen Expired - Fee Related DE60030403D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15144099P 1999-08-30 1999-08-30
PCT/US2000/023878 WO2001016346A1 (en) 1999-08-30 2000-08-30 Production of 3-hydroxypropionic acid in recombinant organisms

Publications (1)

Publication Number Publication Date
DE60030403D1 true DE60030403D1 (de) 2006-10-12

Family

ID=22538777

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60030403T Expired - Fee Related DE60030403D1 (de) 1999-08-30 2000-08-30 Herstellung von 3-hydroxypropionsäure in rekombinanten organismen

Country Status (6)

Country Link
EP (1) EP1124979B1 (de)
AT (1) ATE338139T1 (de)
AU (1) AU7093600A (de)
BR (1) BR0008355A (de)
DE (1) DE60030403D1 (de)
WO (1) WO2001016346A1 (de)

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EP2292749A3 (de) 2004-07-30 2011-12-21 Novozymes A/S Alanine 2, 3 Aminomutasen
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DE102005048818A1 (de) 2005-10-10 2007-04-12 Degussa Ag Mikrobiologische Herstellung von 3-Hydroxypropionsäure
US8030051B2 (en) 2005-10-14 2011-10-04 Codexis, Inc. Alanine 2,3-aminomutases and related polynucleotides
DE102006039203B4 (de) 2006-08-22 2014-06-18 Evonik Degussa Gmbh Verfahren zur Herstellung von durch Kristallisation gereinigter Acrylsäure aus Hydroxypropionsäure sowie Vorrichtung dazu
DE102007015583A1 (de) 2007-03-29 2008-10-02 Albert-Ludwigs-Universität Freiburg Ein Enzym zur Herstellung von Methylmalonyl-Coenzym A oder Ethylmalonyl-Coenzym A sowie dessen Verwendung
US8048624B1 (en) 2007-12-04 2011-11-01 Opx Biotechnologies, Inc. Compositions and methods for 3-hydroxypropionate bio-production from biomass
EP2245137B1 (de) 2008-01-22 2017-08-16 Genomatica, Inc. Verfahren und organismen zur nutzung von synthesegas oder anderen gasförmigen kohlenstoffquellen und methanol
CA3081506A1 (en) 2008-03-05 2009-09-11 Genomatica, Inc. Long chain alcohol-producing organisms
CA2722680A1 (en) 2008-05-01 2009-11-05 Genomatica, Inc. Microorganisms for the production of methacrylic acid
US20110166245A1 (en) 2008-07-30 2011-07-07 Mitsui Chemicals, Inc. Polyester polyol composition for polyurethane, composition for polyurethane foam, polyurethane resin, and polyurethane foam
AU2010242849A1 (en) 2009-04-30 2011-11-24 Genomatica, Inc. Organisms for the production of isopropanol, n-butanol, and isobutanol
EP2424975B1 (de) 2009-04-30 2016-07-06 Genomatica, Inc. Organismen zur herstellung von 1,3-butandiol
CN102428065B (zh) 2009-05-15 2014-02-26 株式会社日本触媒 制备(甲基)丙烯酸的方法
MY152961A (en) 2009-05-15 2014-12-15 Nippon Catalytic Chem Ind Process for producing (meth)acrylic acid
WO2010131603A1 (ja) 2009-05-15 2010-11-18 株式会社日本触媒 (メタ)アクリル酸の製造方法および晶析システム
EP3190174A1 (de) 2009-08-05 2017-07-12 Genomatica, Inc. Aus muconsäureproduzierenden mikroorganismen gewonnene halbsynthetische terephthalsäure
KR20140015136A (ko) 2009-09-27 2014-02-06 더 리젠츠 오브 더 유니버시티 오브 콜로라도, 어 바디 코포레이트 3-히드록시프로피온산 및 다른 생성물의 제조 방법
US8809027B1 (en) 2009-09-27 2014-08-19 Opx Biotechnologies, Inc. Genetically modified organisms for increased microbial production of 3-hydroxypropionic acid involving an oxaloacetate alpha-decarboxylase
WO2011050326A1 (en) 2009-10-23 2011-04-28 Genomatica, Inc. Microorganisms for the production of aniline
EP2495328B1 (de) * 2009-10-29 2016-03-30 Korea Research Institute of Bioscience and Biotechnology Neues verfahren zur herstellung von 3-hydroxypropionsäure aus glycerin
WO2011094131A1 (en) 2010-01-29 2011-08-04 Genomatica, Inc. Microorganisms and methods for the biosynthesis of p-toluate and terephthalate
US9023636B2 (en) 2010-04-30 2015-05-05 Genomatica, Inc. Microorganisms and methods for the biosynthesis of propylene
US8911978B2 (en) 2010-07-02 2014-12-16 Metabolic Explorer Method for the preparation of hydroxy acids
CA2806230A1 (en) 2010-07-26 2012-02-09 Genomatica, Inc. Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene
WO2012019175A2 (en) 2010-08-06 2012-02-09 Mascoma Corporation Production of malonyl-coa drived products via anaerobic pathways
KR20130119945A (ko) 2010-11-22 2013-11-01 노보자임스 인코포레이티드 3-히드록시프로피온산 생산을 위한 조성물 및 방법
EP2660235A4 (de) 2010-12-28 2016-01-20 Nippon Catalytic Chem Ind Verfahren zur herstellung von acrylsäure und/oder einem ester davon und polymer aus der acrylsäure und/oder dem ester davon
CA2849303C (en) 2011-09-30 2019-09-17 Novozymes, Inc. Dehydrogenase variants and polynucleotides encoding same
WO2013085321A1 (ko) * 2011-12-07 2013-06-13 삼성전자주식회사 3-하이드록시프로피온알데히드 및/또는 3-하이드록시프로피온산을 생산하는 재조합 미생물 및 이를 이용한 3-하이드록시프로피온알데히드 및/또는 3-하이드록시프로피온산의 생산방법
KR101494386B1 (ko) * 2011-12-07 2015-02-23 삼성전자주식회사 3-하이드록시프로피온알데히드 및/또는 3-하이드록시프로피온산을 생산하는 재조합 미생물 및 이를 이용한 3-하이드록시프로피온알데히드 및/또는 3-하이드록시프로피온산의 생산방법
US9522867B2 (en) 2012-06-27 2016-12-20 Nippon Shokubai Co., Ltd. (meth)acrylic acid production method, and, hydrophilic resin production method
AU2013299414A1 (en) 2012-08-10 2015-03-26 Opx Biotechnologies, Inc. Microorganisms and methods for the production of fatty acids and fatty acid derived products
WO2014085330A1 (en) 2012-11-30 2014-06-05 Novozymes, Inc. 3-hydroxypropionic acid production by recombinant yeasts
EP2943461B1 (de) 2013-01-08 2019-02-27 Shell International Research Maatschappij B.V. Herstellung von acrylsäure
US20150119601A1 (en) 2013-03-15 2015-04-30 Opx Biotechnologies, Inc. Monofunctional mcr + 3-hp dehydrogenase
CA2905602A1 (en) 2013-03-15 2014-09-18 Sarah M. Hoyt Flash evaporation for product purification and recovery
EP3008179A1 (de) 2013-06-14 2016-04-20 Technical University of Denmark 3hp-toleranz
JP6603658B2 (ja) 2013-07-19 2019-11-06 カーギル インコーポレイテッド 脂肪酸及び脂肪酸誘導体の製造のための微生物及び方法
US11408013B2 (en) 2013-07-19 2022-08-09 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
WO2015058116A1 (en) 2013-10-17 2015-04-23 Cargill, Incorporated Methods for producing alkyl hydroxyalkanoates
EP2993228B1 (de) 2014-09-02 2019-10-09 Cargill, Incorporated Herstellung von fettsäureestern
WO2016061356A1 (en) 2014-10-17 2016-04-21 Cargill, Incorporated Methods for producing an ester of an alpha, beta-unsaturated carboxylic acid
WO2016138303A1 (en) 2015-02-27 2016-09-01 Novozymes A/S Mutant host cells for the production of 3-hydroxypropionic acid
BR112019006051A2 (pt) 2016-09-27 2019-06-25 Shell Int Research processo para produção de álcool alílico
US11345938B2 (en) 2017-02-02 2022-05-31 Cargill, Incorporated Genetically modified cells that produce C6-C10 fatty acid derivatives
CA3086409A1 (en) * 2018-01-16 2019-07-25 Dicerna Pharmaceuticals, Inc. Compositions and methods for inhibiting aldh2 expression
CN115956123A (zh) * 2020-07-31 2023-04-11 株式会社Lg化学 两步制备3-羟基丙酸的方法

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IL129722A0 (en) * 1996-11-13 2000-02-29 Du Pont Method for the production of 1,3-propanediol by recombinant organisms
ATE385521T1 (de) * 1998-08-04 2008-02-15 Metabolix Inc Herstellung von polyhydroxyalkanoaten aus polyolen

Also Published As

Publication number Publication date
AU7093600A (en) 2001-03-26
ATE338139T1 (de) 2006-09-15
WO2001016346A1 (en) 2001-03-08
EP1124979B1 (de) 2006-08-30
EP1124979A1 (de) 2001-08-22
EP1124979A4 (de) 2002-08-28
BR0008355A (pt) 2002-07-16

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