BR112018070645A2 - células de levedura recombinante, métodos para produzir uma célula de levedura e método para produzir um composto alvo - Google Patents

células de levedura recombinante, métodos para produzir uma célula de levedura e método para produzir um composto alvo

Info

Publication number
BR112018070645A2
BR112018070645A2 BR112018070645A BR112018070645A BR112018070645A2 BR 112018070645 A2 BR112018070645 A2 BR 112018070645A2 BR 112018070645 A BR112018070645 A BR 112018070645A BR 112018070645 A BR112018070645 A BR 112018070645A BR 112018070645 A2 BR112018070645 A2 BR 112018070645A2
Authority
BR
Brazil
Prior art keywords
producing
arabinose
methods
target compound
yeast cells
Prior art date
Application number
BR112018070645A
Other languages
English (en)
Inventor
Rice Barbara
Yang Jianjun
Qi Min
Chen Zhongqiang
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of BR112018070645A2 publication Critical patent/BR112018070645A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/16—Butanols
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y503/00—Intramolecular oxidoreductases (5.3)
    • C12Y503/01—Intramolecular oxidoreductases (5.3) interconverting aldoses and ketoses (5.3.1)
    • C12Y503/01004—L-Arabinose isomerase (5.3.1.4)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Abstract

é divulgado um grupo de arabinose isomerases que fornecem quantidades eficazes de atividade para a utilização de arabinose na produção de etanol, quando expressas em células de levedura que expressam as outras enzimas de uma via de utilização de arabinose. o grupo de arabinose isomerases representa um clado de uma árvore filogenética, possuindo um motivo distinto de sequência de aminoácidos conservada. outras arabinose isomerases úteis são também divulgadas.
BR112018070645A 2016-04-08 2017-04-05 células de levedura recombinante, métodos para produzir uma célula de levedura e método para produzir um composto alvo BR112018070645A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662319945P 2016-04-08 2016-04-08
PCT/US2017/026133 WO2017176875A1 (en) 2016-04-08 2017-04-05 Arabinose isomerases for yeast

Publications (1)

Publication Number Publication Date
BR112018070645A2 true BR112018070645A2 (pt) 2019-02-05

Family

ID=58610010

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112018070645A BR112018070645A2 (pt) 2016-04-08 2017-04-05 células de levedura recombinante, métodos para produzir uma célula de levedura e método para produzir um composto alvo

Country Status (4)

Country Link
US (1) US20190112590A1 (pt)
CN (1) CN109415716A (pt)
BR (1) BR112018070645A2 (pt)
WO (1) WO2017176875A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11834692B2 (en) * 2020-02-07 2023-12-05 Trustees Of Tufts College Galactose to tagatose isomerization at moderate temperatures with high conversion and productivity

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US5686276A (en) 1995-05-12 1997-11-11 E. I. Du Pont De Nemours And Company Bioconversion of a fermentable carbon source to 1,3-propanediol by a single microorganism
DE69739715D1 (de) 1996-11-13 2010-02-04 Du Pont Herstellungsverfahren von 1,3-propandiol durch rekombinante organismen
KR100550203B1 (ko) 1997-12-02 2006-02-08 이 아이 듀폰 디 네모아 앤드 캄파니 재조합 유기체에 의한 글리세롤의 생산방법
JP4716634B2 (ja) 1999-08-18 2011-07-06 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー 高力価を有する１，３−プロパンジオールの生物的生産法
JP4334352B2 (ja) 2002-01-23 2009-09-30 ロイヤル ネダルコ ベスローテン フェンノートシャップ ペントース糖の発酵
SE0202090D0 (sv) 2002-05-08 2002-07-04 Forskarpatent I Syd Ab A modifierd yeast consuming L-arabinose
CN102703336A (zh) 2003-05-02 2012-10-03 卡吉尔公司 基因修饰酵母物种和使用基因修饰酵母的发酵方法
SE0302421D0 (sv) 2003-09-11 2003-09-11 Forskarpatent I Syd Ab Construction of new xylose utilizing Saccharomyces cerevisiae strain
SE0400815D0 (sv) 2004-03-26 2004-03-26 Forskarpatent I Syd Ab Traits in recombinant xylose-growing saccharomyces cerevisiae strains using genome-wide transcription analysis
SE0401303D0 (sv) 2004-05-19 2004-05-19 Forskarpatent I Syd Ab Ethanol productivities of microbial strains in fermentation of dilute-acid hydrolyzates depend on their furan reduction capacities
WO2006096130A1 (en) 2005-03-11 2006-09-14 Forskarpatent I Syd Ab Arabinose- and xylose-fermenting saccharomyces cerevisiae strains
CN101160388B (zh) 2005-04-12 2013-05-01 纳幕尔杜邦公司 生物质处理的系统和工艺
EP1874942A4 (en) 2005-04-27 2011-12-14 Scandinavian Technology Group Ab FERMENTATION OF GLUCOSE AND XYLOSE IN CELLULOSIC BIOMASS USING GENETICALLY MODIFIED SACCHAROMYCES CEREVISIAE AND SIMULTANEOUS TREATMENT OF SACCHARIFICATION AND CO-FERMENTATION
US9297028B2 (en) 2005-09-29 2016-03-29 Butamax Advanced Biofuels Llc Fermentive production of four carbon alcohols
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WO2008144012A2 (en) * 2007-05-14 2008-11-27 The Regents Of The University Of California Xylose- and arabinose- metabolizing enzyme -encoding nucleotide sequences with refined translational kinetics and methods of making same
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US20120184007A1 (en) 2009-07-09 2012-07-19 Stephen Picataggio Engineered microorganisms with enhanced fermentation activity
CN102947440B (zh) 2009-12-30 2015-04-08 埃欧金能源公司 呈现增强的木质纤维素水解产物发酵的改良酵母菌株
WO2011131674A1 (en) * 2010-04-21 2011-10-27 Dsm Ip Assets B.V. Process for the production of cells which are capable of converting arabinose
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Also Published As

Publication number Publication date
CN109415716A (zh) 2019-03-01
WO2017176875A1 (en) 2017-10-12
US20190112590A1 (en) 2019-04-18

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Legal Events

Date Code Title Description
B350 Update of information on the portal [chapter 15.35 patent gazette]
B06W Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements