ATE452979T1 - Herstellungsverfahren von 1,3-propandiol durch rekombinante organismen - Google Patents

Herstellungsverfahren von 1,3-propandiol durch rekombinante organismen

Info

Publication number
ATE452979T1
ATE452979T1 AT97947395T AT97947395T ATE452979T1 AT E452979 T1 ATE452979 T1 AT E452979T1 AT 97947395 T AT97947395 T AT 97947395T AT 97947395 T AT97947395 T AT 97947395T AT E452979 T1 ATE452979 T1 AT E452979T1
Authority
AT
Austria
Prior art keywords
protein
seq
propanediol
gene encoding
production process
Prior art date
Application number
AT97947395T
Other languages
English (en)
Inventor
Anthony Gatenby
Sharon Haynie
Vasantha Nagarajan
Ramesh Nair
Charles Nakamura
Mark Payne
Stephen Picataggio
Maria Diaz-Torres
Amy Hsu
Richard Lareau
Donald Trimbur
Gregory Whited
Original Assignee
Du Pont
Genencor Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont, Genencor Int filed Critical Du Pont
Application granted granted Critical
Publication of ATE452979T1 publication Critical patent/ATE452979T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82—Proteins from microorganisms
    • Y10S530/823—Lower fungi, e.g. mold
    • Y10S530/824—Yeasts

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
AT97947395T 1996-11-13 1997-11-10 Herstellungsverfahren von 1,3-propandiol durch rekombinante organismen ATE452979T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3060196P 1996-11-13 1996-11-13
PCT/US1997/020292 WO1998021339A1 (en) 1996-11-13 1997-11-10 Method for the production of 1,3-propanediol by recombinant organisms

Publications (1)

Publication Number Publication Date
ATE452979T1 true ATE452979T1 (de) 2010-01-15

Family

ID=21854996

Family Applications (2)

Application Number Title Priority Date Filing Date
AT97947395T ATE452979T1 (de) 1996-11-13 1997-11-10 Herstellungsverfahren von 1,3-propandiol durch rekombinante organismen
AT97951433T ATE329034T1 (de) 1996-11-13 1997-11-13 Rekombinantes herstellungsverfahren für 1,3- propandiol

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT97951433T ATE329034T1 (de) 1996-11-13 1997-11-13 Rekombinantes herstellungsverfahren für 1,3- propandiol

Country Status (18)

Country Link
US (3) US6013494A (de)
EP (2) EP0942989B1 (de)
JP (2) JP4327909B2 (de)
KR (1) KR100509310B1 (de)
CN (2) CN1236063C (de)
AT (2) ATE452979T1 (de)
AU (2) AU733534B2 (de)
BR (2) BR9712761B1 (de)
CA (2) CA2269088C (de)
DE (2) DE69739715D1 (de)
DK (1) DK0946732T3 (de)
ES (1) ES2336858T3 (de)
ID (1) ID21487A (de)
IL (2) IL129722A0 (de)
MY (1) MY131754A (de)
NZ (1) NZ335392A (de)
WO (2) WO1998021339A1 (de)
ZA (1) ZA9710194B (de)

Families Citing this family (171)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6428767B1 (en) 1995-05-12 2002-08-06 E. I. Du Pont De Nemours And Company Method for identifying the source of carbon in 1,3-propanediol
US5686276A (en) 1995-05-12 1997-11-11 E. I. Du Pont De Nemours And Company Bioconversion of a fermentable carbon source to 1,3-propanediol by a single microorganism
DE69739918D1 (de) * 1996-11-13 2010-08-05 Du Pont Herstellungsverfahren von glycerin durch rekombinante organismen
AU733534B2 (en) * 1996-11-13 2001-05-17 E.I. Du Pont De Nemours And Company Method for the production of 1,3-propanediol by recombinant microorganisms
AU1619199A (en) * 1997-12-02 1999-06-16 E.I. Du Pont De Nemours And Company Method for the production of glycerol by recombinant organisms
GB9806762D0 (en) * 1998-03-31 1998-05-27 Neutec Pharma Plc Treatment and diagnosis of staphylococcal infections
US7074608B1 (en) 1998-05-12 2006-07-11 E. I. Du Pont De Nemours And Company Method for the production of 1,3-propanediol by recombinant organisms comprising genes for coenzyme B12 synthesis
US6432686B1 (en) 1998-05-12 2002-08-13 E. I. Du Pont De Nemours And Company Method for the production of 1,3-propanediol by recombinant organisms comprising genes for vitamin B12 transport
EP1105514B1 (de) 1998-08-04 2008-02-06 Metabolix, Inc. Herstellung von polyhydroxyalkanoaten aus polyolen
US6468773B1 (en) * 1999-05-19 2002-10-22 Genencor International, Inc. Mutant 1,3-propandiol dehydrogenase
FR2796081B1 (fr) 1999-07-09 2003-09-26 Agronomique Inst Nat Rech Procede de preparation du 1,3-propanediol par un micro-organisme recombinant en l'absence de coenzyme b12 ou de l'un de ses precurseurs
US6514733B1 (en) 1999-08-18 2003-02-04 E. I. Du Pont De Nemours And Company Process for the biological production of 1,3-propanediol with high titer
EP1586647A1 (de) * 1999-08-18 2005-10-19 E.I. du Pont de Nemours and Company Verfahren zur biologischen Herstellung von 1,3-propanediol
DE60030403D1 (de) * 1999-08-30 2006-10-12 Wisconsin Alumni Res Found Herstellung von 3-hydroxypropionsäure in rekombinanten organismen
US6803218B1 (en) 1999-09-24 2004-10-12 Genencor Intl., Inc. Enzymes which dehydrate glycerol
FR2800751B1 (fr) 1999-11-09 2003-08-29 Roquette Freres Procede de production de 1,3 propanediol par voie fermentaire
FR2801058B1 (fr) 1999-11-16 2002-01-18 Roquette Freres Procede de purification du 1,3-propanediol a partir d'un milieu de fermentation
US6617478B2 (en) 2000-11-29 2003-09-09 Samsung Electronics Co., Ltd. Process for preparing a 1,3-alkandiol from 3-hydroxyester
EP1211234A3 (de) 2000-11-29 2003-11-26 Samsung Electronics Co., Ltd. Verfahren zur Herstellung von 1,3-Alkandiolen aus 3-Hydroxyestern
EP1575881B1 (de) * 2002-01-18 2009-05-27 Novozymes A/S Alanin-2,3-aminomutase
JP2005523020A (ja) 2002-04-22 2005-08-04 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー 遺伝子工学のためのプロモーターおよびプラスミドシステム
WO2003095655A2 (de) * 2002-05-08 2003-11-20 Basf Plant Science Gmbh Verfahren zum erhöhen des ölgehaltes in pflanzen
DK1578943T3 (da) 2002-08-16 2012-01-09 Danisco Us Inc Nye variant-Hypocrea jecorina-CBH1-cellulaser
JP4592418B2 (ja) 2002-10-04 2010-12-01 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー 高収率での１，３−プロパンジオールの生物生産のための方法
AU2003277276A1 (en) 2002-10-04 2004-05-04 Genencor International, Inc. Improved production of bacterial strains cross reference to related applications
WO2004044210A2 (en) 2002-11-06 2004-05-27 University Of Florida Materials and methods for the efficient production of acetate and other products
KR20050089970A (ko) 2002-12-16 2005-09-09 이 아이 듀폰 디 네모아 앤드 캄파니 반응 속도가 개선된 ｂ１２-의존성 데히드라타제
MXPA05009553A (es) * 2003-03-10 2006-03-17 Broin And Associates Inc Metodo para producir etanol utilizando almidon como materia prima.
US20050233030A1 (en) * 2004-03-10 2005-10-20 Broin And Associates, Inc. Methods and systems for producing ethanol using raw starch and fractionation
WO2004085611A2 (en) * 2003-03-21 2004-10-07 The Research Foundation Of State University Of New York Model for mutually exclusive domain folding molecular switch
CN102517360A (zh) 2003-04-01 2012-06-27 丹尼斯科美国公司 灰腐质霉cbh1.1变体
US7056439B2 (en) * 2003-05-06 2006-06-06 Tate & Lyle Ingredidents Americas, Inc. Process for producing 1, 3-propanediol
CA2522928C (en) * 2003-05-06 2013-09-24 E.I. Du Pont De Nemours And Company Purification of biologically-produced 1,3-propanediol
KR20070019961A (ko) 2003-11-21 2007-02-16 제넨코 인터내셔날 인코포레이티드 트리코데르마에서의 과립 전분 가수분해 효소의 발현 및과립 전분 기질로부터의 글루코스 생성 방법
US20050239181A1 (en) * 2004-03-10 2005-10-27 Broin And Associates, Inc. Continuous process for producing ethanol using raw starch
EP1731604A4 (de) * 2004-03-26 2007-04-04 Nippon Catalytic Chem Ind Verfahren zur herstellung von 1,3-propandiol und/oder 3-hydroxypropionsäure
US20090031453A1 (en) * 2004-07-30 2009-01-29 Holly Jean Jessen Alanine 2, 3 aminomutases
EP1838849B1 (de) 2004-12-30 2015-08-26 Danisco US Inc. Cbh2-cellulasevarianten aus hypocrea jecorina
US7781191B2 (en) * 2005-04-12 2010-08-24 E. I. Du Pont De Nemours And Company Treatment of biomass to obtain a target chemical
JP5804666B2 (ja) * 2005-04-12 2015-11-04 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニーＥ．Ｉ．Ｄｕ Ｐｏｎｔ Ｄｅ Ｎｅｍｏｕｒｓ Ａｎｄ Ｃｏｍｐａｎｙ バイオマスの処理および利用における別の供給流れの集中
US20070029252A1 (en) * 2005-04-12 2007-02-08 Dunson James B Jr System and process for biomass treatment
US20070037267A1 (en) * 2005-05-02 2007-02-15 Broin And Associates, Inc. Methods and systems for producing ethanol using raw starch and fractionation
US7524660B2 (en) 2005-05-05 2009-04-28 E.I. Du Pont De Nemours And Company Utilization of fructose in microbial production strains
CN1327001C (zh) * 2005-06-03 2007-07-18 清华大学 利用生物柴油副产物甘油生产1,3－丙二醇的方法
BRPI0611855A2 (pt) * 2005-06-16 2010-10-05 Wabash Technologies Inc conjunto de pedal com um mecanismo de histerese
CN100427605C (zh) * 2005-06-17 2008-10-22 清华大学 一种由粗淀粉原料生产1,3-丙二醇和2,3-丁二醇的方法
DE102005048818A1 (de) 2005-10-10 2007-04-12 Degussa Ag Mikrobiologische Herstellung von 3-Hydroxypropionsäure
US7919289B2 (en) 2005-10-10 2011-04-05 Poet Research, Inc. Methods and systems for producing ethanol using raw starch and selecting plant material
US8273558B2 (en) 2005-10-26 2012-09-25 Butamax(Tm) Advanced Biofuels Llc Fermentive production of four carbon alcohols
BRPI0619325B8 (pt) 2005-10-26 2020-11-17 Butamax Advanced Biofuels Llc célula hospedeira microbiana recombinante e método para produção de isobutanol
US9303225B2 (en) 2005-10-26 2016-04-05 Butamax Advanced Biofuels Llc Method for the production of isobutanol by recombinant yeast
CN100392071C (zh) * 2005-12-05 2008-06-04 中国农业大学 产乳酸途径缺失的工程菌及其构建方法与应用
CN100463968C (zh) * 2006-01-27 2009-02-25 华侨大学 一种由生物催化转化甘油制备1,3-丙二醇和二羟基丙酮的方法
EA015438B1 (ru) * 2006-02-06 2011-08-30 ДСМ АйПи АССЕТС Б.В. Новые оксидоредуктазы и их применение
ES2797782T3 (es) 2006-02-10 2020-12-03 Dupont Tate & Lyle Bio Products Company Llc Composición que comprende un extracto y 1,3-propanediol de origen biológico como disolvente no irritante
US20070275139A1 (en) * 2006-02-10 2007-11-29 Melissa Joerger Food compositions comprising renewably-based, biodegradable1,3-propanediol
CN1935991B (zh) * 2006-06-21 2010-05-12 南宁中诺生物工程有限责任公司 产气荚膜梭菌甘油脱水酶基因及其1,3-丙二醇的生产方法
JP5130811B2 (ja) * 2006-07-19 2013-01-30 東レ株式会社 連続発酵による１，３−プロパンジオールの製造方法
DE102006039203B4 (de) 2006-08-22 2014-06-18 Evonik Degussa Gmbh Verfahren zur Herstellung von durch Kristallisation gereinigter Acrylsäure aus Hydroxypropionsäure sowie Vorrichtung dazu
WO2008052596A1 (en) * 2006-10-31 2008-05-08 Metabolic Explorer Process for the biological production of n-butanol with high yield
CA2665448A1 (en) * 2006-10-31 2008-05-08 Metabolic Explorer Process for the biological production of 1,3-propanediol from glycerol with high yield
US20080176957A1 (en) * 2006-11-15 2008-07-24 Dupont Tate & Lyle Bio Products Company, Llc Preservative compositions comprising renewably-based, biodegradable 1,3-propanediol
DE102007015583A1 (de) 2007-03-29 2008-10-02 Albert-Ludwigs-Universität Freiburg Ein Enzym zur Herstellung von Methylmalonyl-Coenzym A oder Ethylmalonyl-Coenzym A sowie dessen Verwendung
CN101130782B (zh) * 2007-07-23 2011-01-26 江南大学 以葡萄糖为底物产1,3-丙二醇重组酿酒酵母的构建方法
US7807419B2 (en) * 2007-08-22 2010-10-05 E. I. Du Pont De Nemours And Company Process for concentrated biomass saccharification
US7819976B2 (en) * 2007-08-22 2010-10-26 E. I. Du Pont De Nemours And Company Biomass treatment method
US20090053800A1 (en) * 2007-08-22 2009-02-26 Julie Friend Biomass Treatment Apparatus
US8445236B2 (en) * 2007-08-22 2013-05-21 Alliance For Sustainable Energy Llc Biomass pretreatment
DE102007041862A1 (de) 2007-09-03 2009-03-19 Evonik Degussa Gmbh Mikrobiologische Herstellung von Isoprenoiden
CN101939435A (zh) 2007-09-21 2011-01-05 巴斯夫植物科学有限公司 具有增加的产量的植物
CN101205541B (zh) * 2007-10-18 2010-12-08 北京化工大学 重组表达载体和用其转化的宿主细胞发酵甘油高产1,3-丙二醇的方法
US8048624B1 (en) 2007-12-04 2011-11-01 Opx Biotechnologies, Inc. Compositions and methods for 3-hydroxypropionate bio-production from biomass
DE102007060705A1 (de) 2007-12-17 2009-06-18 Evonik Degussa Gmbh ω-Aminocarbonsäuren oder ihre Lactame, herstellende, rekombinante Zellen
EP3037541A1 (de) 2007-12-17 2016-06-29 Photanol B.V. Lichtgesteuerte co2-reduktion in organischen verbindungen, die als brennstoffe oder industrielle halbzeuge dienen, durch ein autotrophes element mit einer fermentativen genkassette
EP2628795A1 (de) 2008-06-06 2013-08-21 Danisco US Inc. Zusammensetzungen und Verfahren mit Cellulasevarianten mit verminderter Affinität gegenüber cellulosefreien Materialien
DE102008002715A1 (de) 2008-06-27 2009-12-31 Evonik Röhm Gmbh 2-Hydroxyisobuttersäure produzierende rekombinante Zelle
DE102008041299A1 (de) 2008-08-18 2010-02-25 Evonik Degussa Gmbh Neuartiges, universell einsetzbares addiction-System
EP2326709A4 (de) * 2008-09-15 2013-01-23 Opx Biotechnologies Inc Verfahren, systeme und zusammensetzungen in zusammenhang mit reduzierter umwandlung mikrobiell erzeugter 3-hydroxypropionsäure (3-hp) in aldehydmetabolite
US8409839B2 (en) 2008-12-10 2013-04-02 Direvo Industrial Biotechnology Gmbh Polypeptides having cellobiohydrolase II activity
WO2010080489A1 (en) * 2008-12-19 2010-07-15 E. I. Du Pont De Nemours And Company Ozone treatment of biomass to enhance enzymatic saccharification
EP2896700B1 (de) 2009-03-03 2017-08-02 POET Research, Inc. Fermentationssystem zur Herstellung von Ethanol aus Xylose
US9068206B1 (en) 2009-03-03 2015-06-30 Poet Research, Inc. System for treatment of biomass to facilitate the production of ethanol
US20100233771A1 (en) * 2009-03-03 2010-09-16 Mcdonald William F System for pre-treatment of biomass for the production of ethanol
US8450094B1 (en) 2009-03-03 2013-05-28 Poet Research, Inc. System for management of yeast to facilitate the production of ethanol
JP2012528598A (ja) 2009-06-03 2012-11-15 ダニスコ・ユーエス・インク 改善された発現、活性、及び安定性を有するセルラーゼ変異体、並びにこれらの使用方法
US8809027B1 (en) 2009-09-27 2014-08-19 Opx Biotechnologies, Inc. Genetically modified organisms for increased microbial production of 3-hydroxypropionic acid involving an oxaloacetate alpha-decarboxylase
AU2010298004B2 (en) 2009-09-27 2016-02-25 Opx Biotechnologies, Inc. Method for producing 3-hydroxypropionic acid and other products
US8852903B2 (en) 2009-10-23 2014-10-07 E I Du Pont De Nemours And Company Co-metabolism of fructose and glucose in microbial production strains
DE102009046623A1 (de) 2009-11-11 2011-05-12 Evonik Röhm Gmbh Verwendung eines zu einem MeaB-Protein homologen Proteins zur Erhöhung der enzymatischen Aktivität einer 3-Hydroxycarbonsäure-CoA-Mutase
DE102010014680A1 (de) 2009-11-18 2011-08-18 Evonik Degussa GmbH, 45128 Zellen, Nukleinsäuren, Enzyme und deren Verwendung sowie Verfahren zur Herstellung von Sophorolipiden
WO2011063363A2 (en) * 2009-11-20 2011-05-26 Opx Biotechnologies, Inc. Production of an organic acid and/or related chemicals
US20110136190A1 (en) * 2009-12-04 2011-06-09 E. I. Du Pont De Nemours And Company Recombinant bacteria for producing glycerol and glycerol-derived products from sucrose
US8034592B2 (en) * 2009-12-10 2011-10-11 The Curators Of The University Of Missouri Fossil fuel-free process of lignocellulosic pretreatment with biological hydrogen production
CA2788811A1 (en) 2010-02-11 2011-08-18 Metabolix, Inc. Process for gamma-butyrolactone production
KR101144235B1 (ko) * 2010-02-25 2012-05-10 한국과학기술연구원 바이오에탄올 폐발효액을 이용한 부탄올의 제조방법
WO2011132511A1 (ja) * 2010-04-19 2011-10-27 サッポロビール株式会社 新規微生物並びにそれを用いた水素製造方法、１，３－プロパンジオール製造方法及びバイオディーゼル廃液の処理方法
US8721794B2 (en) 2010-04-28 2014-05-13 E I Du Pont De Nemours And Company Production of high solids syrup from lignocellulosic biomass hydrolysate fermentation broth
US8906235B2 (en) 2010-04-28 2014-12-09 E I Du Pont De Nemours And Company Process for liquid/solid separation of lignocellulosic biomass hydrolysate fermentation broth
KR101220499B1 (ko) * 2010-05-25 2013-01-10 한국생명공학연구원 글리세롤로부터 3-하이드록시프로피온산을 고수율로 제조하는 방법
CA2804713C (en) 2010-07-12 2021-04-27 Universiteit Gent Metabolically engineered organisms for the production of added value bio-products
DE102010032484A1 (de) 2010-07-28 2012-02-02 Evonik Goldschmidt Gmbh Zellen und Verfahren zur Herstellung von Rhamnolipiden
WO2012031166A2 (en) * 2010-09-01 2012-03-08 Eric Knight Expression of steady state metabolic pathways
US8129170B1 (en) 2010-12-06 2012-03-06 E.I. Du Pont De Nemours And Company Recombinant bacteria having the ability to metabolize sucrose
BR122019017739B1 (pt) * 2011-04-05 2021-06-22 Lallemand Hungary Liquidity Management Llc Micro-organismo recombinante compreendendo uma deleção de enzimas nativas que atuam para produzir glicerol e/ou regular a síntese de glicerol e vias metabólicas sintéticas para converter uma fonte de carboidrato a etanol
CN104941507B (zh) 2011-04-13 2017-06-16 Elc管理公司 适用于个人护理组合物的温和型阴离子表面活性剂
CN103476914A (zh) 2011-04-13 2013-12-25 Elc管理公司 用于个人护理组合物的调节剂
FR2976949B1 (fr) * 2011-06-21 2015-08-28 Sanofi Sa Procede de preparation de levures genetiquement transformees capables de produire une molecule d'interet a haut titre
US8829206B2 (en) 2011-06-24 2014-09-09 Eastman Chemical Company Production of cyclic acetals or ketals using solid acid catalysts
US8969598B2 (en) 2011-06-24 2015-03-03 Eastman Chemical Company Production of cyclic acetals or ketals using liquid-phase acid catalysts
US9000229B2 (en) 2011-06-24 2015-04-07 Eastman Chemical Company Production of hydroxy ether hydrocarbons by vapor phase hydrogenolysis of cyclic acetals and ketals
US8829207B2 (en) 2011-06-24 2014-09-09 Eastman Chemical Company Production of cyclic acetals by reactive distillation
US9388105B2 (en) 2011-06-24 2016-07-12 Eastman Chemical Company Production of hydroxy ether hydrocarbons by liquid phase hydrogenolysis of cyclic acetals or cyclic ketals
US8785697B2 (en) 2011-06-24 2014-07-22 Eastman Chemical Company Nickel modified catalyst for the production of hydroxy ether hydrocarbons by vapor phase hydrogenolysis of cyclic acetals and ketals
US9056313B2 (en) 2011-06-24 2015-06-16 Eastman Chemical Company Catalysts for the production of hydroxy ether hydrocarbons by vapor phase hydrogenolysis of cyclic acetals and ketals
EP2540834A1 (de) 2011-06-29 2013-01-02 Metabolic Explorer Verfahren zur Herstellung von 1,3-Propandiol
JP2013013353A (ja) * 2011-07-01 2013-01-24 Daicel Corp １，３−プロパンジオールの製造方法
JP2013070675A (ja) * 2011-09-28 2013-04-22 Daicel Corp アルキルジオールを産生する組換え菌の培養方法
DE102012201360A1 (de) 2012-01-31 2013-08-01 Evonik Industries Ag Zellen und Verfahren zur Herstellung von Rhamnolipiden
US9017961B2 (en) 2012-03-05 2015-04-28 E.I. Du Pont De Nemours And Company Recombinant bacteria comprising novel sucrose transporters
US8686114B2 (en) 2012-03-05 2014-04-01 E I Du Pont De Nemours And Company Variant sucrose transporter polypeptides
CN102634543A (zh) * 2012-05-04 2012-08-15 杭玉玲 微生物发酵生产1,3-丙二醇的方法
WO2013185009A1 (en) 2012-06-08 2013-12-12 Metabolix, Inc. Renewable acrylic acid production and products made therefrom
KR20150040359A (ko) 2012-08-10 2015-04-14 오피엑스 바이오테크놀로지스, 인크. 지방산 및 지방산 유도된 산물의 생산을 위한 미생물 및 방법
KR101437040B1 (ko) * 2012-08-17 2014-09-02 삼성전자 주식회사 삼투압 보호제 첨가에 의한 1,3-프로판디올 생산방법 및 생산용 배지
KR102121888B1 (ko) * 2012-08-28 2020-06-12 란자테크 뉴질랜드 리미티드 재조합 미생물 및 이에 대한 용도
KR20150093190A (ko) 2012-12-12 2015-08-17 다니스코 유에스 인크. 셀로바이오하이드롤라제의 변이체
US20140178954A1 (en) 2012-12-20 2014-06-26 E I Du Pont De Nemours And Company Expression of xylose isomerase activity in yeast
WO2014127053A2 (en) 2013-02-13 2014-08-21 Metabolix, Inc. Process for ultra pure chemical production from biobased raw starting materials
US9187743B2 (en) 2013-03-11 2015-11-17 E I Du Pont De Nemours And Company Bacterial xylose isomerases active in yeast cells
US8669076B1 (en) 2013-03-11 2014-03-11 E I Du Pont De Nemours And Company Cow rumen xylose isomerases active in yeast cells
US20140273105A1 (en) 2013-03-12 2014-09-18 E I Du Pont De Nemours And Company Gradient pretreatment of lignocellulosic biomass
US20140315258A1 (en) 2013-03-14 2014-10-23 Abengoa Bioenergy New Technologies, Llc Methods for converting cellulosic waste to bioproducts
US10584860B2 (en) * 2013-03-14 2020-03-10 Ideal Industries, Llc Linear light fixture with interchangeable light engine unit
CA2905912A1 (en) * 2013-03-14 2014-10-02 E. I. Du Pont De Nemours And Company Glycerol 3- phosphate dehydrogenase for butanol production
US20150119601A1 (en) 2013-03-15 2015-04-30 Opx Biotechnologies, Inc. Monofunctional mcr + 3-hp dehydrogenase
CA2905602A1 (en) 2013-03-15 2014-09-18 Sarah M. Hoyt Flash evaporation for product purification and recovery
JP6603658B2 (ja) 2013-07-19 2019-11-06 カーギル インコーポレイテッド 脂肪酸及び脂肪酸誘導体の製造のための微生物及び方法
US11408013B2 (en) 2013-07-19 2022-08-09 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
CA2922120C (en) 2013-09-03 2022-09-06 Myriant Corporation A process for manufacturing acrylic acid, acrylonitrile and 1,4-butanediol from 1,3-propanediol
CN105531373A (zh) * 2013-09-06 2016-04-27 密苏里州立大学校董 盐碱条件下甘油向1,3-丙二醇的转化
US10227623B2 (en) 2013-11-24 2019-03-12 E I Du Pont De Nemours And Company High force and high stress destructuring of cellulosic biomass
KR101532736B1 (ko) 2014-02-24 2015-07-09 한국생명공학연구원 2,3-부탄디올 합성 유전자가 결실된 미생물 변이체를 이용한 1,3-프로판디올의 제조방법
FR3015186A1 (fr) * 2014-03-11 2015-06-26 Antoine Piccirilli Utilisation d'une composition renfermant du 1,3-propanediol comme e-liquide
EP2949214A1 (de) 2014-05-26 2015-12-02 Evonik Degussa GmbH Verfahren zur Herstellung von Rhamnolipiden
WO2016007350A1 (en) 2014-07-09 2016-01-14 Danisco Us Inc. Preconditioning of lignocellulosic biomass
EP2993228B1 (de) 2014-09-02 2019-10-09 Cargill, Incorporated Herstellung von fettsäureestern
EP3056561A1 (de) 2015-02-16 2016-08-17 Evonik Degussa GmbH Mikroorganismen mit reduzierter Enzymaktivität
WO2016131801A1 (en) 2015-02-19 2016-08-25 Evonik Degussa Gmbh Rhamnolipid synthesis
WO2016171285A1 (ja) * 2015-04-20 2016-10-27 パイクリスタル株式会社 アクティブマトリクスアレイ装置の製造方法とこれにより製造されたアクティブマトリクスアレイ装置
CN104774879B (zh) * 2015-04-29 2017-10-20 大连理工大学 一种混菌发酵甘油生产1,3‑丙二醇的方法
WO2017017292A1 (es) 2015-07-29 2017-02-02 Abengoa Bioenergía Nuevas Tecnologías, S. A. Expresión de enzimas beta-xilosidasas recombinantes
US9968531B2 (en) 2015-08-05 2018-05-15 Dupont Tate & Lyle Bio Products Company, Llc Deodorants containing 1,3-propanediol
EP3192866A1 (de) 2016-01-15 2017-07-19 CIC nanoGUNE - Asociación Centro de Investigación Cooperativa en Nanociencias Endocellulasen und verwendungen davon
CN109415716A (zh) 2016-04-08 2019-03-01 纳幕尔杜邦公司 用于酵母的阿拉伯糖异构酶
BR112019008320A2 (pt) 2016-10-24 2020-01-28 Evonik Degussa Gmbh células e método para produzir ramnolipídios com o uso de transportadores de glicose alternativos
BR112019008321A2 (pt) 2016-10-24 2020-01-28 Evonik Degussa Gmbh célula e método de produção de ramnolipídeo que tem atividade de glicose desidrogenase reduzida e seu uso
EP3577227A4 (de) 2017-02-02 2020-12-30 Cargill Inc. Genetisch veränderte zellen, die c6-c10-fettsäurederivate produzieren
EP3502126A1 (de) 2017-12-19 2019-06-26 CIC nanoGUNE - Asociación Centro de Investigación Cooperativa en Nanociencias Anzestrale cellulasen und verwendungen davon
KR102103408B1 (ko) * 2018-01-16 2020-04-23 한국과학기술원 1,3-프로판디올 생성능을 가지는 변이미생물 및 이를 이용한 1,3-pdo의 제조방법
US20190233853A1 (en) * 2018-02-01 2019-08-01 Invista North America S.A.R.L. Methods and materials for the biosynthesis of beta hydroxy acids and/or derivatives thereof and/or compounds related thereto
US11236372B2 (en) 2018-02-09 2022-02-01 Evonik Operations Gmbh Lipid production
JP6668577B1 (ja) * 2018-10-30 2020-03-18 ＧｒｅｅｎＥａｒｔｈＩｎｓｔｉｔｕｔｅ株式会社 １，３−プロパンジオールの製造方法
CN109370969B (zh) * 2018-11-12 2020-09-04 江南大学 一种重组克雷伯氏杆菌在制备1，3-丙二醇中的应用
CN109337852B (zh) * 2018-11-12 2020-09-04 江南大学 一种重组克雷伯氏杆菌在生产1,3-丙二醇中的应用
CN109750011B (zh) * 2019-02-20 2022-05-10 中国科学院天津工业生物技术研究所 一种甘露糖6-磷酸磷酸酶及甘露糖生物制备方法
KR20210128742A (ko) * 2020-04-17 2021-10-27 에스케이이노베이션 주식회사 글리세롤 생성이 억제된 재조합 내산성 효모 및 이를 이용한 젖산의 제조방법
CN116323929A (zh) * 2020-11-05 2023-06-23 株式会社Lg化学 具有从葡萄糖生产3-羟基丙酸能力的微生物及其用途
CN112625994B (zh) * 2021-01-05 2022-04-15 清华大学 一种重组需钠弧菌及其应用
CN114806981B (zh) * 2021-01-18 2023-05-23 中国科学院上海高等研究院 克雷伯氏菌工程菌在生产1,3-丙二醇中的应用
CN114107145B (zh) * 2021-11-04 2024-05-07 清华大学 一种重组微生物及其在生产1,3-丙二醇中的应用
WO2024231217A1 (en) 2023-05-11 2024-11-14 Evonik Operations Gmbh Glucolipid production

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3634764A1 (de) 1986-10-11 1988-04-14 Mueller Haidmann Roland Dipl I Aus platten zusammengesetzte decke
DE3734764A1 (de) * 1987-10-14 1989-05-03 Huels Chemische Werke Ag Verfahren zur herstellung von propandiol-(1,3)
EP0373230B1 (de) * 1988-12-12 1993-02-17 Unilever N.V. Verfahren zur mikrobiologischen Herstellung von 1,3-Propandiol aus Glycerin
US5686276A (en) * 1995-05-12 1997-11-11 E. I. Du Pont De Nemours And Company Bioconversion of a fermentable carbon source to 1,3-propanediol by a single microorganism
US5599689A (en) * 1995-05-12 1997-02-04 E. I. Du Pont De Nemours And Company Process for making 1,3-propanediol from carbohydrates using mixed microbial cultures
US5633362A (en) * 1995-05-12 1997-05-27 E. I. Du Pont De Nemours And Company Production of 1,3-propanediol from glycerol by recombinant bacteria expressing recombinant diol dehydratase
AU733534B2 (en) * 1996-11-13 2001-05-17 E.I. Du Pont De Nemours And Company Method for the production of 1,3-propanediol by recombinant microorganisms

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