TN2013000368A1 - Glucosylceramide synthase inhibitors - Google Patents

Glucosylceramide synthase inhibitors

Info

Publication number
TN2013000368A1
TN2013000368A1 TNP2013000368A TN2013000368A TN2013000368A1 TN 2013000368 A1 TN2013000368 A1 TN 2013000368A1 TN P2013000368 A TNP2013000368 A TN P2013000368A TN 2013000368 A TN2013000368 A TN 2013000368A TN 2013000368 A1 TN2013000368 A1 TN 2013000368A1
Authority
TN
Tunisia
Prior art keywords
glucosylceramide synthase
synthase inhibitors
treatment
inhibitors
glucosylceramide
Prior art date
Application number
TNP2013000368A
Other languages
French (fr)
Inventor
Elyse Bourque
Cassandra Celatka
Bradford Hirth
Markus Metz
Zhong Zhao
Renato Skerlj
Yibin Xiang
Katherine Jancisics
John Marshall
Seng Cheng
Ronald Scheule
Mario Cabrera-Salazar
Andrew Good
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2012/029417 external-priority patent/WO2012129084A2/en
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of TN2013000368A1 publication Critical patent/TN2013000368A1/en

Links

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention relates to inhibitors of glucosylceramide synthase (GCS) useful for the treatment metabolic diseases, such as lysosomal storage diseases, either alone or in combination with enzyme replacement therapy, and for the treatment of cancer.
TNP2013000368A 2012-01-25 2013-09-17 Glucosylceramide synthase inhibitors TN2013000368A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261590711P 2012-01-25 2012-01-25
PCT/US2012/029417 WO2012129084A2 (en) 2011-03-18 2012-03-16 Glucosylceramide synthase inhibitors

Publications (1)

Publication Number Publication Date
TN2013000368A1 true TN2013000368A1 (en) 2015-01-20

Family

ID=54337514

Family Applications (1)

Application Number Title Priority Date Filing Date
TNP2013000368A TN2013000368A1 (en) 2012-01-25 2013-09-17 Glucosylceramide synthase inhibitors

Country Status (1)

Country Link
TN (1) TN2013000368A1 (en)

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