ZA201303544B - Compositions and methods for 3-hydroxypropionic acid production - Google Patents

Compositions and methods for 3-hydroxypropionic acid production

Info

Publication number
ZA201303544B
ZA201303544B ZA2013/03544A ZA201303544A ZA201303544B ZA 201303544 B ZA201303544 B ZA 201303544B ZA 2013/03544 A ZA2013/03544 A ZA 2013/03544A ZA 201303544 A ZA201303544 A ZA 201303544A ZA 201303544 B ZA201303544 B ZA 201303544B
Authority
ZA
South Africa
Prior art keywords
compositions
methods
acid production
hydroxypropionic acid
hydroxypropionic
Prior art date
Application number
ZA2013/03544A
Other languages
English (en)
Inventor
Holly Jessen
Jeanette Huryta
Alan Berry
Michael Catlett
Brian Rush
Beth Mastel
Debbie Yaver
Michelle Barnhardt
Original Assignee
Novozymes As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes As filed Critical Novozymes As
Publication of ZA201303544B publication Critical patent/ZA201303544B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • C12N1/18—Baker's yeast; Brewer's yeast
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/52—Propionic acid; Butyric acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01059—3-Hydroxypropionate dehydrogenase (1.1.1.59)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y206/00—Transferases transferring nitrogenous groups (2.6)
    • C12Y206/01—Transaminases (2.6.1)
    • C12Y206/01001—Aspartate transaminase (2.6.1.1), i.e. aspartate-aminotransferase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y206/00—Transferases transferring nitrogenous groups (2.6)
    • C12Y206/01—Transaminases (2.6.1)
    • C12Y206/01018—Beta-alanine-pyruvate transaminase (2.6.1.18)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y206/00—Transferases transferring nitrogenous groups (2.6)
    • C12Y206/01—Transaminases (2.6.1)
    • C12Y206/01019—4-Aminobutyrate—2-oxoglutarate transaminase (2.6.1.19)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y401/00—Carbon-carbon lyases (4.1)
    • C12Y401/01—Carboxy-lyases (4.1.1)
    • C12Y401/01031—Phosphoenolpyruvate carboxylase (4.1.1.31)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Botany (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ZA2013/03544A 2010-11-22 2013-05-15 Compositions and methods for 3-hydroxypropionic acid production ZA201303544B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41619910P 2010-11-22 2010-11-22
US201161535181P 2011-09-15 2011-09-15
PCT/US2011/061717 WO2012074818A2 (en) 2010-11-22 2011-11-21 Compositions and methods for 3-hydroxypropionic acid production

Publications (1)

Publication Number Publication Date
ZA201303544B true ZA201303544B (en) 2014-11-26

Family

ID=45099210

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2013/03544A ZA201303544B (en) 2010-11-22 2013-05-15 Compositions and methods for 3-hydroxypropionic acid production

Country Status (11)

Country Link
US (7) US9090918B2 (enExample)
EP (2) EP3287519B1 (enExample)
JP (1) JP6061862B2 (enExample)
KR (1) KR20130119945A (enExample)
CN (2) CN103502432A (enExample)
AU (1) AU2011336923B2 (enExample)
BR (1) BR112013012630B1 (enExample)
CA (1) CA2818499A1 (enExample)
MX (1) MX2013005654A (enExample)
WO (1) WO2012074818A2 (enExample)
ZA (1) ZA201303544B (enExample)

Families Citing this family (96)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2620770T3 (es) 2006-03-13 2017-06-29 Cargill, Incorporated Proceso de fermentación que emplea células de levadura que tienen una ruta alterada desde dihidroxiacetona fosfato hasta glicerol
WO2012019175A2 (en) * 2010-08-06 2012-02-09 Mascoma Corporation Production of malonyl-coa drived products via anaerobic pathways
CN103502432A (zh) 2010-11-22 2014-01-08 诺维信股份有限公司 用于生产3-羟基丙酸的组合物和方法
CA2885934C (en) * 2010-11-22 2018-05-01 Cargill, Incorporated Compositions and methods for increased ethanol titer from biomass
CN103813709A (zh) * 2011-06-28 2014-05-21 布鲁克黑文科学联合会 具有增加的油含量的经修饰植物
WO2013028912A2 (en) * 2011-08-24 2013-02-28 Novozymes, Inc. Methods for producing multiple recombinant polypeptides in a filamentous fungal host cell
EP2751261B1 (en) 2011-09-30 2018-08-29 Novozymes, Inc. Dehydrogenase variants and polynucleotides encoding same
AU2013230930B2 (en) * 2012-03-06 2018-10-11 Lygos, Inc. Recombinant host cells for the production of malonate
IN2014DN10168A (enExample) * 2012-05-30 2015-08-21 Lanzatech New Zealand Ltd
EP2882843A4 (en) 2012-08-10 2016-04-06 Opx Biotechnologies Inc MICRO-ORGANISMS AND METHOD FOR THE PRODUCTION OF FATTY ACIDS AND PRODUCTS DERIVED FROM FATTY ACIDS
WO2014057036A1 (en) 2012-10-11 2014-04-17 Technical University Of Denmark Genetically engineered yeast
EP2925873B1 (en) 2012-11-30 2017-07-12 Novozymes, Inc. 3-hydroxypropionic acid production by recombinant yeasts
ES2735024T3 (es) * 2013-03-14 2019-12-13 Du Pont Glicerol-3-fosfato deshidrogenasa para la producción de butanol
US20150057465A1 (en) 2013-03-15 2015-02-26 Opx Biotechnologies, Inc. Control of growth-induction-production phases
PL2970086T3 (pl) 2013-03-15 2019-04-30 Cargill Inc Odzyskiwanie kwasu 3-hydroksypropionowego
US20150044746A1 (en) * 2013-03-15 2015-02-12 Opx Biotechnologies, Inc. Method of enhanced bioproduction
EP3008178A1 (en) 2013-06-14 2016-04-20 Technical University of Denmark Microbial production of 3-hydroxypropionic acid
WO2014198841A1 (en) 2013-06-14 2014-12-18 Technical University Of Denmark 3hp tolerance
US11408013B2 (en) 2013-07-19 2022-08-09 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
US9556443B2 (en) 2013-07-19 2017-01-31 Samsung Electronics Co., Ltd. Yeast cell with inactivated NADH dehydrogenase and method of producing lactate using the yeast cell
CN106795483A (zh) 2013-07-19 2017-05-31 嘉吉公司 用于生产脂肪酸和脂肪酸衍生产物的微生物及方法
US9845484B2 (en) 2013-07-31 2017-12-19 Novozymes A/S 3-hydroxypropionic acid production by recombinant yeasts expressing an insect aspartate 1-decarboxylase
WO2015031504A1 (en) * 2013-08-27 2015-03-05 The Regents Of The University Of California RECOMBINANT PATHWAY AND ORGANISMS FOR MALONYL-CoA SYNTHESIS
BR112016005241B1 (pt) 2013-09-12 2020-12-08 Basf Se processo para desidratar continuamente ácido 3-hidroxipropiônico aquoso para ácido acrílico aquoso na fase líquida
WO2015036278A1 (de) 2013-09-12 2015-03-19 Basf Se Verfahren zur dehydratisierung von 3-hydroxypropionsäure zu acrylsäure
WO2015036273A1 (de) 2013-09-12 2015-03-19 Basf Se Verfahren zur herstellung von acrylsäure
JP6488666B2 (ja) * 2013-11-22 2019-03-27 Ａｇｃ株式会社 クローニングベクター、発現ベクターおよび形質転換体の製造方法
EP3072955B1 (en) 2013-11-22 2019-01-09 JMTC Enzyme Corporation Transformant and process for production thereof, and process for production of lactic acid
KR101555867B1 (ko) 2014-04-18 2015-10-01 부산대학교 산학협력단 3-하이드록시프로피온산을 분해하지 않는 슈도모나스 데니트리피칸스 결실 변이균주 및 이를 이용한 3-하이드록시프로피온산의 생산방법
EP3161142A4 (en) * 2014-06-26 2018-05-16 Lygos, Inc. Recombinant host cells for the production of malonate
WO2016026763A1 (en) 2014-08-18 2016-02-25 Basf Se Process for preparing acrylic acid using a heterogeneous alumina catalyst
JP6786477B2 (ja) * 2014-08-29 2020-11-18 エスケー イノベーション カンパニー リミテッドＳｋ Ｉｎｎｏｖａｔｉｏｎ Ｃｏ．，Ｌｔｄ． ３−ｈｐを生産することができる組換え酵母およびこれを利用した３−ｈｐの製造方法
EP2993228B1 (en) 2014-09-02 2019-10-09 Cargill, Incorporated Production of fatty acid esters
US10214754B2 (en) 2014-10-10 2019-02-26 Jmtc Enzyme Corporation Transformant and its production process, and method for producing lactic acid
US20180273915A1 (en) * 2014-12-19 2018-09-27 Novozymes A/S Recombinant Host Cells For The Production Of 3-Hydroxypropionic Acid
WO2016100910A1 (en) * 2014-12-19 2016-06-23 Novozymes A/S Recombinant host cells for the production of 3-hydroxypropionic acid
WO2016135020A1 (de) 2015-02-24 2016-09-01 Basf Se Verfahren zur kontinuierlichen dehydratisierung von 3-hydroxypropionsäure zu acrylsäure
EP3262161B1 (en) 2015-02-27 2021-06-30 Novozymes A/S Mutant host cells for the production of 3-hydroxypropionic acid
WO2016162175A1 (de) 2015-04-07 2016-10-13 Basf Se Verfahren zur dehydratisierung von 3-hydroxypropionsäure zu acrylsäure
WO2016200239A1 (ko) * 2015-06-11 2016-12-15 부산대학교 산학협력단 3-하이드록시프로피온산에 의해 발현이 유도되는 프로모터 시스템 및 이를 이용한 3-하이드록시프로피온산의 생물학적 생산방법
KR101877303B1 (ko) 2015-06-11 2018-07-11 (주)노루홀딩스 3-하이드록시프로피온산에 의해 발현이 유도되는 프로모터 시스템 및 이를 이용한 3-하이드록시프로피온산의 생물학적 생산방법
CN107849522A (zh) * 2015-07-21 2018-03-27 多伦多大学管理委员会 用于产生1,3‑丁二醇的方法和微生物
WO2017035270A1 (en) * 2015-08-24 2017-03-02 Novozymes A/S Beta-alanine aminotransferases for the production of 3-hydroxypropionic acid
CN109072172A (zh) * 2015-11-12 2018-12-21 利戈斯股份有限公司 用于厌氧产生L-天冬氨酸和β-丙氨酸的重组宿主细胞和方法
US20180258437A1 (en) * 2015-11-12 2018-09-13 Lygos, Inc. Recombinant host cells and methods for the production of l-aspartate and beta-alanine
DE102016114555A1 (de) 2016-08-05 2018-02-08 Thyssenkrupp Ag Prozess zur Herstellung von Acrylsäure aus einer wässrigen 3-Hydroxypropanol-Lösung
WO2018106792A1 (en) 2016-12-06 2018-06-14 Novozymes A/S Improved processes for production of ethanol from xylose-containing cellulosic substrates using engineered yeast strains
WO2018144701A2 (en) 2017-02-02 2018-08-09 Cargill Incorporated Genetically modified cells that produce c6-c10 fatty acid derivatives
WO2018220116A1 (en) 2017-05-31 2018-12-06 Novozymes A/S Xylose fermenting yeast strains and processes thereof for ethanol production
AU2018275794A1 (en) 2017-06-02 2019-12-05 Novozymes A/S Improved yeast for ethanol production
MY200321A (en) 2017-08-17 2023-12-20 Basf Se Process for continuously preparing n-butyl acrylate or isobutyl acrylate
AU2018322748B2 (en) 2017-08-29 2024-05-02 Novozymes A/S Baker's yeast expressing anti-staling/freshness amylases
MX2020007914A (es) 2018-01-29 2020-10-28 Novozymes As Microorganismos con uso de nitrogeno mejorado para produccion de etanol.
KR102419608B1 (ko) * 2018-02-08 2022-07-08 주식회사 엘지화학 고농도 3-하이드록시프로피온산 수용액의 제조 방법
WO2019231944A2 (en) 2018-05-31 2019-12-05 Novozymes A/S Processes for enhancing yeast growth and productivity
US20220119821A1 (en) * 2018-06-25 2022-04-21 Lygos, Inc. Recombinant host cells and methods for the production of aspartic acid and b-alanine
CN112601818A (zh) 2018-07-25 2021-04-02 诺维信公司 用于生产乙醇的表达酶的酵母
WO2020076697A1 (en) 2018-10-08 2020-04-16 Novozymes A/S Enzyme-expressing yeast for ethanol production
JP7370587B2 (ja) * 2018-10-30 2023-10-30 ＧｒｅｅｎＥａｒｔｈＩｎｓｔｉｔｕｔｅ株式会社 有機化合物の製造方法およびコリネ型細菌
WO2020128618A2 (en) * 2018-12-18 2020-06-25 Braskem S.A. Co-production pathway for 3-hp and acetyl-coa derivatives from malonate semialdehyde
CN109852605A (zh) * 2019-01-16 2019-06-07 徐州工程学院 一种诱变筛选高产3-羟基丙酸菌株的方法
MX2021015821A (es) 2019-07-26 2022-02-03 Novozymes As Microorganismos con transporte de nitrogeno mejorado para la produccion de etanol.
CN112390855B (zh) * 2019-07-31 2022-04-29 上海交通大学医学院附属仁济医院 Pretide-146a在制备缓解或治疗自身免疫性疾病的药物中的应用
EP4009807A1 (en) 2019-08-05 2022-06-15 Novozymes A/S Enzyme blends and processes for producing a high protein feed ingredient from a whole stillage byproduct
MX2021015818A (es) 2019-08-06 2022-02-03 Novozymes As Proteinas de fusion para mejorar la expresion de enzimas.
AU2020340444A1 (en) 2019-08-30 2022-04-14 Lygos, Inc. Recombinant host cells for the production of malonate
EP4031661A1 (en) 2019-09-16 2022-07-27 Novozymes A/S Polypeptides having beta-glucanase activity and polynucleotides encoding same
CA3158982A1 (en) 2019-12-10 2021-06-17 Monica TASSONE Microorganism for improved pentose fermentation
WO2021163030A2 (en) 2020-02-10 2021-08-19 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
EP4171773B1 (de) 2020-06-29 2024-07-10 Basf Se Vorrichtung zur durchführung von stoffaustauschprozessen
US20230265466A1 (en) * 2020-07-31 2023-08-24 Lg Chem, Ltd. Method for preparing 3-hydroxypropionic acid through two steps
CN111985041B (zh) * 2020-09-17 2021-03-30 青岛理工大学 一种加固边坡挡墙高度确定方法及加固边坡挡墙
US10894812B1 (en) 2020-09-30 2021-01-19 Alpine Roads, Inc. Recombinant milk proteins
KR20230076829A (ko) * 2020-09-30 2023-05-31 게노미엄, 아이엔씨. 바이오아크롤레인 및 바이오아크릴산을 생산하는 발효 공정
US10947552B1 (en) 2020-09-30 2021-03-16 Alpine Roads, Inc. Recombinant fusion proteins for producing milk proteins in plants
WO2022072718A1 (en) 2020-09-30 2022-04-07 Nobell Foods, Inc. Recombinant milk proteins and food compositions comprising the same
AU2021370998A1 (en) 2020-11-02 2023-05-25 Novozymes A/S Glucoamylase variants and polynucleotides encoding same
WO2022098162A1 (ko) * 2020-11-05 2022-05-12 주식회사 엘지화학 3-하이드록시프로피온산의 생산 방법
US20230348942A1 (en) * 2020-11-05 2023-11-02 Lg Chem, Ltd. Microorganisms having capability of producing 3-hydroxypropionic acid from glucose and uses thereof
AU2022218205A1 (en) 2021-02-08 2023-05-25 Lanzatech, Inc. Recombinant microorganisms and uses therefor
BR112023025624A2 (pt) 2021-06-07 2024-02-27 Novozymes As Célula de levedura recombinante, célula hospedeira recombinante, composição, cocultura, métodos de produção de um derivado de uma célula hospedeira recombinante e de produção de um produto de fermentação, e, uso de uma célula hospedeira recombinante
FR3125048B1 (fr) 2021-07-09 2024-04-19 Snf Sa Polymère biosourcé à biodégradabilité améliorée
FR3125040B1 (fr) 2021-07-09 2024-04-26 Snf Sa Procédé d’obtention de bio-monomère à partir de diméthylaminoethanol d’origine renouvelable
FR3125042B1 (fr) 2021-07-09 2024-04-12 Snf Sa Procédé d’obtention d’alkyl(méth)acrylamide substitué biosourcé
WO2023168233A1 (en) 2022-03-03 2023-09-07 Cargill, Incorporated Genetically modified yeast and fermentation processes for the production of 3-hydroxypropionate
WO2023168244A1 (en) 2022-03-03 2023-09-07 Cargill, Incorporated Genetically modified yeast and fermentation processes for the production of 3-hydroxypropionate
CN115595328B (zh) * 2022-03-07 2026-02-13 中国科学院微生物研究所 天冬氨酸脱羧酶在发酵生产维生素b5中的应用
CN116024184B (zh) * 2022-07-26 2024-03-15 南京科技职业学院 醛脱氢酶突变体及其在制备5-羟甲基-2-呋喃甲酸中的应用
CN120283060A (zh) 2022-12-19 2025-07-08 诺维信公司 用于使用纤维降解酶和工程化酵母生产发酵产物的工艺
CN116463274A (zh) * 2023-03-23 2023-07-21 浙江工业大学 一种高产d-泛酸的益生工程菌及其在产d-泛酸和制备益生菌添加剂中的应用
WO2024226289A1 (en) 2023-04-26 2024-10-31 Cargill, Incorporated Methods for producing propionic acid
AU2024303961A1 (en) 2023-06-13 2025-12-11 Novozymes A/S Processes for producing fermentation products using engineered yeast expressing a beta-xylosidase
CN117025696A (zh) * 2023-08-16 2023-11-10 台州学院 一种(2s,3r)-对甲砜基苯丝氨酸的制备方法
CN121794035A (zh) 2023-09-15 2026-04-03 嘉吉公司 升膜蒸发器原位清洁方法和系统
WO2025165198A1 (ko) * 2024-01-31 2025-08-07 주식회사 엘지화학 3-하이드록시프로피온산의 생산 방법
WO2025261823A1 (en) 2024-06-21 2025-12-26 Basf Se Process for manufacture of (meth)acrylates

Family Cites Families (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL39710A (en) 1972-06-19 1975-04-25 Imi Inst For Res & Dev Recovery of acids from aqueous solutions by solvent extraction
US4771001A (en) 1986-03-27 1988-09-13 Neurex Corp. Production of lactic acid by continuous fermentation using an inexpensive raw material and a simplified method of lactic acid purification
US5210296A (en) 1990-11-19 1993-05-11 E. I. Du Pont De Nemours And Company Recovery of lactate esters and lactic acid from fermentation broth
US5132456A (en) 1991-05-07 1992-07-21 The Regents Of The University Of California Sorption of carboxylic acid from carboxylic salt solutions at PHS close to or above the pKa of the acid, with regeneration with an aqueous solution of ammonia or low-molecular-weight alkylamine
US5420304A (en) 1992-03-19 1995-05-30 Biopak Technology, Ltd. Method to produce cyclic esters
AT398982B (de) 1993-02-18 1995-02-27 Vogelbusch Gmbh Verfahren zur abtrennung und reinigung von milchsäure
US5510526A (en) 1993-06-29 1996-04-23 Cargill, Incorporated Lactic acid production, separation and/or recovery process
IL109003A (en) 1994-03-16 1999-09-22 Yissum Res Dev Co Process and extractant composition for extracting water-soluble carboxylic and mineral acids
IT1294728B1 (it) 1997-09-12 1999-04-12 Biopolo S C A R L Ceppi di lievito per la riproduzione di acido lattico
AU760575C (en) 1998-04-13 2005-04-14 University Of Georgia Research Foundation, Inc., The Pyruvate carboxylase overexpression for enhanced production of oxaloacetate-derived biochemicals in microbial cells
EP1105514B1 (en) * 1998-08-04 2008-02-06 Metabolix, Inc. Polyhydroxyalkanoate production from polyols
EP1183385B1 (en) 1999-05-21 2006-07-19 Cargill Dow LLC Methods and materials for the synthesis of organic products
ATE338139T1 (de) 1999-08-30 2006-09-15 Wisconsin Alumni Res Found Herstellung von 3-hydroxypropionsäure in rekombinanten organismen
US6852517B1 (en) 1999-08-30 2005-02-08 Wisconsin Alumni Research Foundation Production of 3-hydroxypropionic acid in recombinant organisms
JP4098455B2 (ja) 2000-03-10 2008-06-11 株式会社日立製作所 マーク画像中の電子透かし情報の参照方法及び計算機
AU2002219818B2 (en) 2000-11-20 2007-08-16 Cargill, Incorporated 3-hydroxypropionic acid and other organic compounds
CN1955299A (zh) 2000-11-22 2007-05-02 内特尔沃克公司 合成有机产物的方法和材料
AU2002311989A1 (en) 2001-11-23 2003-06-23 Cargill Dow Polymers Llc Methods and materials for the production of organic products in cells of $i(candida) species
US7309597B2 (en) 2002-01-18 2007-12-18 Cargill, Incorporated Alanine 2,3-Aminomutase
CN1781897A (zh) 2002-03-25 2006-06-07 嘉吉有限公司 制造β－羟基羧酸烷氧基衍生物的方法
ATE367436T1 (de) 2002-05-30 2007-08-15 Natureworks Llc Verfahren und materialien zur produktion von d- milchsäure in hefe
CA2503967A1 (en) 2002-11-01 2004-05-21 Cargill, Incorporated Process for preparation of 1,3-propanediol
AU2004215369A1 (en) 2003-02-24 2004-09-10 Cargill Incorporated Process for preparing 3-hydroxycarboxylic acids
ATE437850T1 (de) 2003-06-26 2009-08-15 Novozymes As Verfahren zur trennung und rückgewinnung von 3- hydroxypropionsäure und acrylsäure
WO2005021470A2 (en) 2003-06-26 2005-03-10 Cargill, Incorporated Process for separating and recovering 3-hydroxypropionic acid and acrylic acid
US7326557B2 (en) 2003-11-14 2008-02-05 Rice University Increasing intracellular NADPH availability in E. coli
ATE543873T1 (de) 2003-12-04 2012-02-15 Novozymes As Herstellung von 3-hydroxypropionsäure mittels beta-alanine-pyruvat-aminotrransferase
EP1786831A4 (en) 2004-07-30 2008-01-23 Cargill Inc Alanine 2,3-aminomutases
US7987056B2 (en) 2004-09-20 2011-07-26 The Regents Of The University Of Colorado, A Body Corporate Mixed-library parallel gene mapping quantitative micro-array technique for genome-wide identification of trait conferring genes
AU2005299399A1 (en) 2004-10-25 2006-05-04 Codexis, Inc. Improved alanine 2,3-aminomutases and related polynucleotides
ES2401339T3 (es) 2005-08-10 2013-04-18 University Of Florida Research Foundation, Inc. Materiales y métodos para producción eficiente de ácido láctico
US7846688B2 (en) 2005-08-15 2010-12-07 The Regents Of The University Of Colorado Broad host range vectors for shotgun and expression library cloning in Gram negative bacteria
DE102005048818A1 (de) * 2005-10-10 2007-04-12 Degussa Ag Mikrobiologische Herstellung von 3-Hydroxypropionsäure
ES2620770T3 (es) 2006-03-13 2017-06-29 Cargill, Incorporated Proceso de fermentación que emplea células de levadura que tienen una ruta alterada desde dihidroxiacetona fosfato hasta glicerol
WO2007130745A1 (en) 2006-03-15 2007-11-15 Regents Of The University Of Colorado Enhanced alcohol tolerant microorganism and methods of use thereof
WO2008021765A2 (en) 2006-08-08 2008-02-21 Regents Of The University Of Colorado Compositions and methods for chemical reporter vectors
WO2008027742A1 (en) * 2006-08-30 2008-03-06 Cargill, Incorporated Beta-alanine/alpha-ketoglutarate aminotransferase for 3-hydroxypropionic acid production
US8938765B2 (en) 2006-12-22 2015-01-20 Time Warner Cable Enterprises Llc Methods, apparatus and user interface for providing content on demand
BRPI0806695A2 (pt) 2007-01-12 2014-06-03 Univ Colorado Composições e métodos para aumentar a tolerância à produção de produtos químicos produzidos por microorganismos
US8673601B2 (en) 2007-01-22 2014-03-18 Genomatica, Inc. Methods and organisms for growth-coupled production of 3-hydroxypropionic acid
US8048624B1 (en) 2007-12-04 2011-11-01 Opx Biotechnologies, Inc. Compositions and methods for 3-hydroxypropionate bio-production from biomass
EP2235173A2 (en) 2007-12-19 2010-10-06 Novozymes A/S Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
WO2009089457A1 (en) * 2008-01-11 2009-07-16 Novozymes A/S Methods for producing 3-hydroxypropionic acid and compounds thereof
US20110190513A1 (en) 2008-07-08 2011-08-04 Lynch Michael D Methods, compositions and systems for biosynthetic bio-production of 1,4-butanediol
CN102317436B (zh) * 2008-07-23 2014-06-25 Opx生物工艺学公司 用于增加微生物对3-羟基丙酸(3-hp)的耐受性以及增加3-羟基丙酸产量的方法、系统和组合物
US20100021978A1 (en) * 2008-07-23 2010-01-28 Genomatica, Inc. Methods and organisms for production of 3-hydroxypropionic acid
WO2010017230A2 (en) 2008-08-04 2010-02-11 The Regents Of The University Of Colorado Methods, systems and compositions related to microbial bio-production of butanol and/or isobutanol
WO2010031083A2 (en) * 2008-09-15 2010-03-18 Opx Biotechnologies, Inc. Methods, systems and compositions related to reduction of conversions of microbially produced 3-hydroxypropionic acid (3-hp) to aldehyde metabolites
WO2010059424A2 (en) 2008-11-18 2010-05-27 Novozymes, Inc. Methods and compositions for degrading cellulosic material
US20110144377A1 (en) 2009-06-16 2011-06-16 E. I. Du Pont Nemours And Company Process for the biological production of 3-hydroxypropionic acid with high yield
US8809027B1 (en) 2009-09-27 2014-08-19 Opx Biotechnologies, Inc. Genetically modified organisms for increased microbial production of 3-hydroxypropionic acid involving an oxaloacetate alpha-decarboxylase
JP2013505727A (ja) 2009-09-27 2013-02-21 オーピーエックス バイオテクノロジーズ， インコーポレイテッド ３−ヒドロキシプロピオン酸および他の生成物を生成するための方法
WO2011050037A1 (en) 2009-10-23 2011-04-28 Novozymes, Inc. Cellobiohydrolase variants and polynucleotides encoding same
WO2011059740A1 (en) 2009-10-29 2011-05-19 Novozymes, Inc. Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
US20110125118A1 (en) 2009-11-20 2011-05-26 Opx Biotechnologies, Inc. Production of an Organic Acid and/or Related Chemicals
KR20120136349A (ko) 2010-01-27 2012-12-18 더 리젠츠 오브 더 유니버시티 오브 콜로라도, 어 바디 코포레이트 고가의 화학적 생성물의 미생물 생산, 및 관련 조성물, 방법 및 시스템
CN102834521B (zh) 2010-03-30 2018-02-27 诺维信公司 用于增强来自发酵工艺副产物的方法
WO2012021401A1 (en) 2010-08-12 2012-02-16 Novozymes, Inc. Compositions comprising a polypeptide having cellulolytic enhancing activity and a bicyclic compound and uses thereof
CN103502432A (zh) * 2010-11-22 2014-01-08 诺维信股份有限公司 用于生产3-羟基丙酸的组合物和方法
US20140121118A1 (en) 2010-11-23 2014-05-01 Opx Biotechnologies, Inc. Methods, systems and compositions regarding multiplex construction protein amino-acid substitutions and identification of sequence-activity relationships, to provide gene replacement such as with tagged mutant genes, such as via efficient homologous recombination
EP2864282A4 (en) 2012-06-20 2016-01-20 Opx Biotechnologies Inc CLEANING OF 3-HYDROXYPROPIONIC ACID FROM RAW CELLBOUILLON AND DEHYDRATION TO ACRYLIC ACID
US20130345470A1 (en) 2012-06-20 2013-12-26 Opx Biotechnologies, Inc. Purification of 3-Hydroxypropionic Acid from Crude Cell Broth and Production of Acrylamide
PL2970086T3 (pl) 2013-03-15 2019-04-30 Cargill Inc Odzyskiwanie kwasu 3-hydroksypropionowego
EP2976141A4 (en) 2013-03-15 2016-10-05 Cargill Inc FLASHING FOR PRODUCTION CLEANING AND RECOVERY
WO2014145343A1 (en) 2013-03-15 2014-09-18 Opx Biotechnologies, Inc. Bioproduction of chemicals
US20150057465A1 (en) 2013-03-15 2015-02-26 Opx Biotechnologies, Inc. Control of growth-induction-production phases
US20150044746A1 (en) 2013-03-15 2015-02-12 Opx Biotechnologies, Inc. Method of enhanced bioproduction

Also Published As

Publication number Publication date
MX2013005654A (es) 2013-07-17
US11118187B2 (en) 2021-09-14
CN107828671A (zh) 2018-03-23
US10633664B2 (en) 2020-04-28
CN103502432A (zh) 2014-01-08
EP3287519A1 (en) 2018-02-28
US9090918B2 (en) 2015-07-28
US20220064654A1 (en) 2022-03-03
AU2011336923B2 (en) 2017-02-16
KR20130119945A (ko) 2013-11-01
CA2818499A1 (en) 2012-06-07
US10260072B2 (en) 2019-04-16
US12054721B2 (en) 2024-08-06
JP2013542747A (ja) 2013-11-28
JP6061862B2 (ja) 2017-01-18
US20190249181A1 (en) 2019-08-15
US20160177317A1 (en) 2016-06-23
WO2012074818A3 (en) 2012-09-27
US20200291408A1 (en) 2020-09-17
US9777280B2 (en) 2017-10-03
AU2011336923A1 (en) 2013-05-30
US20180044684A1 (en) 2018-02-15
EP2643450A2 (en) 2013-10-02
WO2012074818A2 (en) 2012-06-07
BR112013012630B1 (pt) 2021-09-08
BR112013012630A2 (pt) 2020-09-24
US20120135481A1 (en) 2012-05-31
US20140065681A1 (en) 2014-03-06
CN107828671B (zh) 2022-03-08
EP3287519B1 (en) 2020-03-18

Similar Documents

Publication Publication Date Title
ZA201308086B (en) Derivatives of 1-anino-2-cyclopropylboronic acid
EP2545178A4 (en) ACIDIFICATION BY FERMENTATION
ZA201308606B (en) Nutritional compositions having alpha-hica and eicosapentaenoic acid
SI2637710T1 (sl) Formulacije na osnovi hialuronske kisline
EP2527400A4 (en) polylactic acid
SG11201404601QA (en) Acetic acid production method
IL222548A0 (en) Novel hydroxamic acid derivative
IL227699A0 (en) Preparations containing peroxy alpha-ketocarboxylic acid and methods for their production and use
IL223153A0 (en) Compositions comprising acid and derivatives thereof and uses thereof
PL2534252T3 (pl) Sposób wytwarzania kwasu mlekowego
SG11201406131SA (en) Process for making ethylene and acetic acid
EP2646412A4 (en) SYNTHETIC ACID AND ASSOCIATED METHODS
ZA201205713B (en) Process for manufacturing succinic acid
SG10201604562PA (en) Biotechnological production of 3-hydroxyisobutyric acid
EP2578725A4 (en) COATED ELEMENT AND METHOD FOR PRODUCING THE SAME
ZA201400918B (en) Pyrrolidine-3-ylacetic acid derivative
EP2616430A4 (en) NOVEL PHENOXYISOBUTYRIC ACID COMPONENTS AND METHODS OF SYNTHESIS
EP2782902A4 (en) DERIVATIVES FROM PHENOXYISOBUTTERIC ACID
ZA201108148B (en) Triazine-aryl-bis-indoles and process for preparation thereof
GB201021522D0 (en) Novel compounds and methods for their production
HU1000328D0 (en) Nanostuctured indometachine compositions and process for their preparation
HU1000329D0 (en) Nanostuctured ibuprofene compositions and process for their preparation
GB201121663D0 (en) Process and compositions
HU1000693D0 (en) Sweetener composition and process for its production
PL390162A1 (pl) Sposób otrzymywania kwasu akrylowego