SG10201604562PA - Biotechnological production of 3-hydroxyisobutyric acid - Google Patents

Biotechnological production of 3-hydroxyisobutyric acid

Info

Publication number
SG10201604562PA
SG10201604562PA SG10201604562PA SG10201604562PA SG10201604562PA SG 10201604562P A SG10201604562P A SG 10201604562PA SG 10201604562P A SG10201604562P A SG 10201604562PA SG 10201604562P A SG10201604562P A SG 10201604562PA SG 10201604562P A SG10201604562P A SG 10201604562PA
Authority
SG
Singapore
Prior art keywords
hydroxyisobutyric acid
biotechnological production
biotechnological
production
hydroxyisobutyric
Prior art date
Application number
SG10201604562PA
Inventor
Thomas Haas
Steffen Schaffer
Markus Pötter
Mirja Wessel
Jan Christoph Pfeffer
Christian Gehring
Nicole Kirchner
Eva Maria Wittmann
Original Assignee
Evonik Degussa Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evonik Degussa Gmbh filed Critical Evonik Degussa Gmbh
Publication of SG10201604562PA publication Critical patent/SG10201604562PA/en

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42Hydroxy-carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/001Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1217Phosphotransferases with a carboxyl group as acceptor (2.7.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/13Transferases (2.) transferring sulfur containing groups (2.8)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93Ligases (6)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y103/00Oxidoreductases acting on the CH-CH group of donors (1.3)
    • C12Y103/99Oxidoreductases acting on the CH-CH group of donors (1.3) with other acceptors (1.3.99)
    • C12Y103/99002Butyryl-CoA dehydrogenase (1.3.99.2), i.e. short chain acyl-CoA dehydrogenase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y207/00Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/02Phosphotransferases with a carboxy group as acceptor (2.7.2)
    • C12Y207/02007Butyrate kinase (2.7.2.7)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y402/00Carbon-oxygen lyases (4.2)
    • C12Y402/01Hydro-lyases (4.2.1)
    • C12Y402/01017Enoyl-CoA hydratase (4.2.1.17), i.e. crotonase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y602/00Ligases forming carbon-sulfur bonds (6.2)
    • C12Y602/01Acid-Thiol Ligases (6.2.1)
    • C12Y602/01002Butyrate-CoA ligase (6.2.1.2)
SG10201604562PA 2011-12-05 2012-11-14 Biotechnological production of 3-hydroxyisobutyric acid SG10201604562PA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP11191923.9A EP2602329A1 (en) 2011-12-05 2011-12-05 Biotechnological production of 3-hydroxyisobutyric acid

Publications (1)

Publication Number Publication Date
SG10201604562PA true SG10201604562PA (en) 2016-07-28

Family

ID=47172641

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201604562PA SG10201604562PA (en) 2011-12-05 2012-11-14 Biotechnological production of 3-hydroxyisobutyric acid
SG11201402979PA SG11201402979PA (en) 2011-12-05 2012-11-14 Biotechnological production of 3-hydroxyisobutyric acid

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201402979PA SG11201402979PA (en) 2011-12-05 2012-11-14 Biotechnological production of 3-hydroxyisobutyric acid

Country Status (10)

Country Link
US (1) US20150218600A1 (en)
EP (2) EP2602329A1 (en)
KR (1) KR20140101890A (en)
CN (1) CN103958691A (en)
BR (1) BR112014013474A2 (en)
CA (1) CA2857986A1 (en)
PH (1) PH12014501161A1 (en)
RU (1) RU2014127326A (en)
SG (2) SG10201604562PA (en)
WO (1) WO2013083374A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2602328A1 (en) * 2011-12-05 2013-06-12 Evonik Industries AG Method of Oxidation of alkanes employing an AlkB alkane 1-monooxygenase
EP2607479A1 (en) 2011-12-22 2013-06-26 Evonik Industries AG Biotechnological production of alcohols and derivatives thereof
EP2631298A1 (en) 2012-02-22 2013-08-28 Evonik Industries AG Biotechnological method for producing butanol and butyric acid
EP2647696A1 (en) 2012-04-02 2013-10-09 Evonik Degussa GmbH Method for aerobic production of alanine or a compound arising using alanine
DE102012207921A1 (en) * 2012-05-11 2013-11-14 Evonik Industries Ag Multi-stage synthesis process with synthesis gas
EP2746400A1 (en) 2012-12-21 2014-06-25 Evonik Industries AG Preparation of amines and diamines from a carboxylic acid or dicarboxylic acid or a monoester thereof
EP2759598A1 (en) 2013-01-24 2014-07-30 Evonik Industries AG Process for preparing alpha, omega alkanediols
EP2944697A1 (en) 2014-05-13 2015-11-18 Evonik Degussa GmbH Method of producing nylon
EP2944696A1 (en) 2014-05-13 2015-11-18 Evonik Degussa GmbH Method of producing organic compounds
CA2937594A1 (en) 2015-02-26 2016-08-26 Evonik Degussa Gmbh Alkene production
WO2017102952A1 (en) 2015-12-17 2017-06-22 Evonik Degussa Gmbh A genetically modified acetogenic cell
CN109790106A (en) 2016-07-27 2019-05-21 赢创德固赛有限公司 N- acetylhomoserine

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002070645A2 (en) 2001-03-02 2002-09-12 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Functional surface display of polypeptides
DE102004005280B4 (en) * 2004-01-29 2007-02-22 Rotop Pharmaka Gmbh Process and pharmaceutical kit for the preparation of rhenium-188 labeled microspheres
DE102006025821A1 (en) 2006-06-02 2007-12-06 Degussa Gmbh An enzyme for the production of Mehylmalonatsemialdehyd or Malonatsemialdehyd
DE102007015583A1 (en) 2007-03-29 2008-10-02 Albert-Ludwigs-Universität Freiburg An enzyme for the production of methylmalonyl-coenzyme A or ethylmalonyl-coenzyme A and its use
CA2688292C (en) * 2007-06-01 2015-01-27 Evonik Roehm Gmbh A process for preparing methacrylic acid or methacrylic esters
DE102007060705A1 (en) 2007-12-17 2009-06-18 Evonik Degussa Gmbh ω-aminocarboxylic acids or their lactams, producing, recombinant cells
CN103562398A (en) * 2011-03-22 2014-02-05 Opx生物工艺学公司 Microbial production of chemical products and related compositions, methods and systems

Also Published As

Publication number Publication date
US20150218600A1 (en) 2015-08-06
RU2014127326A (en) 2016-02-10
SG11201402979PA (en) 2014-11-27
WO2013083374A1 (en) 2013-06-13
PH12014501161A1 (en) 2014-08-11
CN103958691A (en) 2014-07-30
EP2788494A1 (en) 2014-10-15
CA2857986A1 (en) 2013-06-13
KR20140101890A (en) 2014-08-20
BR112014013474A2 (en) 2019-09-24
EP2602329A1 (en) 2013-06-12

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