JP2013535203A - 芳香族、2,4−ペンタジエノエートおよび1,3−ブタジエンを生合成するための微生物および方法 - Google Patents

芳香族、2,4−ペンタジエノエートおよび1,3−ブタジエンを生合成するための微生物および方法 Download PDF

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JP2013535203A
JP2013535203A JP2013521907A JP2013521907A JP2013535203A JP 2013535203 A JP2013535203 A JP 2013535203A JP 2013521907 A JP2013521907 A JP 2013521907A JP 2013521907 A JP2013521907 A JP 2013521907A JP 2013535203 A JP2013535203 A JP 2013535203A
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coa
reductase
dehydratase
naturally occurring
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オスターハウト,ロビン,イー.
バーガード,アンソニー,ピー.
ファーキャ,プリティ
バーク,マーク,ジェイ.
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Genomatica Inc
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JP2013521907A 2010-07-26 2011-07-26 芳香族、2,4−ペンタジエノエートおよび1,3−ブタジエンを生合成するための微生物および方法 Pending JP2013535203A (ja)

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Application Number Priority Date Filing Date Title
US36779210P 2010-07-26 2010-07-26
US61/367,792 2010-07-26
US36822310P 2010-07-27 2010-07-27
US61/368,223 2010-07-27
US38140710P 2010-09-09 2010-09-09
US61/381,407 2010-09-09
PCT/US2011/045364 WO2012018624A2 (en) 2010-07-26 2011-07-26 Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene

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JP2013535203A5 JP2013535203A5 (enExample) 2014-09-11

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JP2016235414A Pending JP2017060518A (ja) 2010-07-26 2016-12-02 芳香族、2,4−ペンタジエノエートおよび1,3−ブタジエンを生合成するための微生物および方法

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KR (1) KR20130043170A (enExample)
CN (1) CN103025877A (enExample)
AU (1) AU2011286199A1 (enExample)
BR (1) BR112013001635A2 (enExample)
CA (1) CA2806230A1 (enExample)
CO (1) CO6680664A2 (enExample)
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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015042711A (ja) * 2013-08-26 2015-03-05 住友ゴム工業株式会社 乗用車タイヤ用キャップトレッドゴム組成物、乗用車タイヤ用キャップトレッドゴム、及び乗用車用空気入りタイヤ
JP2017088708A (ja) * 2015-11-06 2017-05-25 住友ベークライト株式会社 ポリアミド樹脂およびポリアミド樹脂の製造方法
WO2018030526A1 (ja) * 2016-08-12 2018-02-15 旭硝子株式会社 形質転換体および3-ヒドロキシプロピオン酸の製造方法
WO2019107516A1 (ja) 2017-11-30 2019-06-06 東レ株式会社 3-ヒドロキシアジピン酸、α-ヒドロムコン酸および/またはアジピン酸を生産するための遺伝子改変微生物および当該化学品の製造方法
WO2020230719A1 (ja) 2019-05-10 2020-11-19 東レ株式会社 3-ヒドロキシアジピン酸、α-ヒドロムコン酸および/またはアジピン酸を生産するための遺伝子改変微生物および当該化学品の製造方法
JPWO2020230718A1 (enExample) * 2019-05-10 2020-11-19
JP2021177785A (ja) * 2013-12-05 2021-11-18 ジェノマティカ, インコーポレイテッド 脂肪アミンの微生物生産方法
WO2022102635A1 (ja) 2020-11-11 2022-05-19 東レ株式会社 3-ヒドロキシアジピン酸および/またはα-ヒドロムコン酸を生産するための遺伝子改変微生物および当該化学品の製造方法

Families Citing this family (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009155382A1 (en) 2008-06-17 2009-12-23 Genomatica, Inc. Microorganisms and methods for the biosynthesis of fumarate, malate, and acrylate
CA2746952A1 (en) 2008-12-16 2010-06-24 Genomatica, Inc. Microorganisms and methods for conversion of syngas and other carbon sources to useful products
WO2010144746A2 (en) * 2009-06-10 2010-12-16 Genomatica, Inc. Microorganisms and methods for carbon-efficient biosynthesis of mek and 2-butanol
CN102753698A (zh) 2009-12-10 2012-10-24 基因组股份公司 合成气或其他气态碳源和甲醇转化为1,3-丁二醇的方法和有机体
CN102834508A (zh) * 2010-01-29 2012-12-19 基因组股份公司 用于生物合成对甲苯甲酸和对苯二甲酸的微生物和方法
US8637286B2 (en) * 2010-02-23 2014-01-28 Genomatica, Inc. Methods for increasing product yields
US9422578B2 (en) 2011-06-17 2016-08-23 Invista North America S.A.R.L. Methods for biosynthesizing 1,3 butadiene
WO2012174439A2 (en) 2011-06-17 2012-12-20 Invista Technologies S.A R.L. Methods of producing four carbon molecules
WO2013082542A2 (en) * 2011-12-02 2013-06-06 Invista North America S.A.R.L. Methods for biosynthesizing 1,3butadiene
US20130034884A1 (en) * 2011-06-22 2013-02-07 Genomatica, Inc. Microorganisms for producing 1,4-butanediol and methods related thereto
EP2791342B1 (en) 2011-12-16 2020-04-29 Braskem S.A. Modified microorganisms and methods of making butadiene using same
JP6231011B2 (ja) * 2011-12-20 2017-11-15 サイエンティスト・オブ・フォーチュン・ソシエテ・アノニム 3−ヒドロキシアルク−4−エノエートおよび/または3−ホスホノキシアルク−4−エノエートの酵素変換による1,3−ジエンの産生
US20150017698A1 (en) * 2012-03-02 2015-01-15 Codexis, Inc. a corporation Recombinant host cells and processes for producing 1,3-butadiene through a 5-hydroxypent-3-enoate intermediate
EP2861745A2 (en) * 2012-06-15 2015-04-22 Invista Technologies S.à.r.l. Methods for biosynthesizing 1,3 butadiene
US20150152440A1 (en) * 2012-06-18 2015-06-04 Braskem S.A. Modified microorganisms and methods of co-producing butadiene with 1-propanol and/or 1,2-propanediol
US20150211024A1 (en) * 2012-08-28 2015-07-30 Braskem S.A. Methods for production of a terpene and a co-product
US8703455B2 (en) * 2012-08-29 2014-04-22 Scientist of Fourtune, S.A. Production of volatile dienes by enzymatic dehydration of light alkenols
JP5536840B2 (ja) * 2012-09-07 2014-07-02 住友ゴム工業株式会社 タイヤ用ゴム組成物、タイヤ部材、及び空気入りタイヤ
US20140134687A1 (en) * 2012-10-02 2014-05-15 Braskem S/A Ap 09 Modified microorganisms and methods of using same for producing butadiene and succinate
WO2014066892A1 (en) * 2012-10-26 2014-05-01 Coelho Pedro S De novo metabolic pathways for isoprene biosynthesis
EP2925871A1 (en) 2012-11-28 2015-10-07 Invista Technologies S.A R.L. Methods for biosynthesis of isobutene
WO2014106122A1 (en) * 2012-12-31 2014-07-03 Genomatica, Inc. Compositions and methods for bio-butadiene production screening
US9034629B2 (en) 2013-01-25 2015-05-19 Joule Unlimited Technologies, Inc. Recombinant synthesis of medium chain-length alkanes
MX2015009532A (es) * 2013-01-25 2016-05-09 Joule Unltd Technologies Inc Sintesis recombinante de alcanos.
WO2014152434A2 (en) 2013-03-15 2014-09-25 Genomatica, Inc. Microorganisms and methods for producing butadiene and related compounds by formate assimilation
CA2908572A1 (en) 2013-05-17 2014-11-20 Global Bioenergies Alkenol dehydratase variants
US10294496B2 (en) 2013-07-19 2019-05-21 Invista North America S.A.R.L. Methods for biosynthesizing 1,3 butadiene
US10273518B2 (en) 2013-07-29 2019-04-30 Invista North America S.A.R.L. Methods for biosynthesizing 3-oxopent-4-enoyl-CoA
WO2015021045A2 (en) 2013-08-05 2015-02-12 INVISTA North America S.á r.l. Methods for biosynthesis of isoprene
BR112016002626A2 (pt) 2013-08-05 2017-09-12 Invista Tech Sarl método para sintetizar isobuteno e hospedeiro recombinante
WO2015041776A1 (en) * 2013-09-18 2015-03-26 Arizona Board Of Regents On Behalf Of Arizona State University Enzymes and microorganisms for the production of 1,3-butadiene and other dienes other dienes
PL3077501T3 (pl) 2013-12-03 2022-01-31 Genomatica, Inc. Mikroorganizmy i sposoby poprawy wydajności produktu na metanolu z użyciem syntezy acetylo-coa
ES2800606T3 (es) 2013-12-27 2021-01-04 Genomatica Inc Métodos y organismos con mayores eficiencias del flujo de carbono
US9938543B2 (en) 2014-06-16 2018-04-10 Invista North America S.A.R.L. Methods, reagents and cells for biosynthesizing glutarate methyl ester
US10669561B2 (en) 2014-07-03 2020-06-02 Genomatica, Inc. Microorganisms for producing 4C-5C compounds with unsaturation and methods related thereto
US10487342B2 (en) * 2014-07-11 2019-11-26 Genomatica, Inc. Microorganisms and methods for the production of butadiene using acetyl-CoA
US20170298363A1 (en) 2014-09-18 2017-10-19 Genomatica, Inc Non-natural microbial organisms with improved energetic efficiency
BR112017010010A2 (pt) * 2014-11-14 2018-02-06 Invista Tech Sarl método para produzir 3-oxo-5-hidroxipentanoil-coa, método para biossintetizar 1,3-butanodiol, hospedeiro recombinante, produto bioderivado, produto biobaseado ou produto derivado de fermentação, retícula bioquímica de ocorrência não natural, construto de ácido nucleico ou vetor de expressão e composição
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BR112017025554B1 (pt) 2015-05-30 2024-03-12 Genomatica, Inc. Composição, e, método para produzir um polímero, resina ou artigo de fabricação
WO2016199966A1 (ko) * 2015-06-12 2016-12-15 씨제이제일제당 주식회사 젖산 생산이 향상된 미생물 및 이를 이용하여 젖산을 생산하는 방법
EP3368548B1 (en) 2015-10-30 2023-08-23 Genomatica, Inc. Methanol dehydrogenase fusion proteins
EP3377639A2 (en) 2015-11-17 2018-09-26 Global Bioenergies Methods for producing isobutene from 3-methylcrotonic acid
CN105678109A (zh) * 2016-01-11 2016-06-15 天津师范大学 一种基于邻接蛋白的蛋白功能注释方法
US10510434B2 (en) 2016-02-15 2019-12-17 Samsung Electronics Co., Ltd. Device and method of selecting pathway of target compound
CN106222122A (zh) * 2016-07-20 2016-12-14 江南大学 大肠杆菌工程菌及其催化马来酸合成富马酸的方法
EP3330380A1 (en) * 2016-12-05 2018-06-06 Evonik Degussa GmbH Process for producing l-methionine from methional
CN108624628B (zh) * 2017-03-22 2022-09-13 中国科学院天津工业生物技术研究所 催化甲酸合成甲醛car酶的制备及其应用
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CA3059650C (en) 2017-05-10 2023-12-19 Global Bioenergies Improved methods for producing isobutene from 3-methylcrotonic acid
US11162115B2 (en) 2017-06-30 2021-11-02 Inv Nylon Chemicals Americas, Llc Methods, synthetic hosts and reagents for the biosynthesis of hydrocarbons
US11634733B2 (en) 2017-06-30 2023-04-25 Inv Nylon Chemicals Americas, Llc Methods, materials, synthetic hosts and reagents for the biosynthesis of hydrocarbons and derivatives thereof
US11708590B2 (en) 2017-07-18 2023-07-25 Arizona Board Of Regents On Behalf Of Arizona State University Synthetic metabolic funneling for biochemical production
US11505809B2 (en) 2017-09-28 2022-11-22 Inv Nylon Chemicals Americas Llc Organisms and biosynthetic processes for hydrocarbon synthesis
CN108103038B (zh) * 2017-12-15 2021-03-02 江南大学 一种合成l-苯甘氨酸的单细胞工厂及其构建与应用
US20210079334A1 (en) 2018-01-30 2021-03-18 Genomatica, Inc. Fermentation systems and methods with substantially uniform volumetric uptake rate of a reactive gaseous component
CN108753802B (zh) * 2018-05-22 2021-07-16 昆明理工大学 一个苹果酸脱氢酶基因cimdh1及其重组表达载体
US11541105B2 (en) 2018-06-01 2023-01-03 The Research Foundation For The State University Of New York Compositions and methods for disrupting biofilm formation and maintenance
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JP6668577B1 (ja) * 2018-10-30 2020-03-18 GreenEarthInstitute株式会社 1,3−プロパンジオールの製造方法
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WO2021092162A1 (en) * 2019-11-05 2021-05-14 Aditya Kunjapur Biosynthesis of para-nitro-l-phenylalanine
CN112522171A (zh) * 2020-12-18 2021-03-19 浙江中山化工集团股份有限公司 一种工程菌、含鸟氨酸溶液的处理方法及试剂盒
EP4269593A4 (en) * 2020-12-28 2025-08-13 Riken PROCESS FOR PRODUCING AN UNSATURATED CHAIN CARBOXYLIC ACID COMPOUND USING PHENYLALANINE AMMONIA LYASE
CN113913321B (zh) * 2021-07-28 2023-06-09 暨南大学 一株苯甲酸钠降解菌株及其应用
CN115851563B (zh) * 2022-10-13 2023-10-20 深圳中科翎碳生物科技有限公司 固定二氧化碳电合成3-羟基丁酸的工程菌及构建方法
CN116240231A (zh) * 2022-12-19 2023-06-09 中国科学院电工研究所 一种纳米酶级联反应系统及其制备方法和应用
CN116426584A (zh) * 2023-06-14 2023-07-14 山东福瑞达生物科技有限公司 一种提高四氢嘧啶发酵产量的方法
CN117430125B (zh) * 2023-10-23 2025-03-21 常州大学 一种锰掺杂含有介孔结构的酸性Beta沸石分子筛的制备方法及其应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101329232A (zh) * 2008-07-28 2008-12-24 中国烟草总公司郑州烟草研究院 基于热裂解-气相色谱质谱联用技术的烟用香原料筛选方法
WO2009111513A1 (en) * 2008-03-03 2009-09-11 Joule Biotechnologies, Inc. Engineered co2 fixing microorganisms producing carbon-based products of interest

Family Cites Families (175)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4076948A (en) 1968-10-10 1978-02-28 El Paso Products Company Process for treatment of adipic acid mother liquor
US3513209A (en) 1968-08-19 1970-05-19 Du Pont Method of making 1,4-cyclohexadiene
GB1230276A (enExample) 1968-12-09 1971-04-28
US3965182A (en) 1969-10-02 1976-06-22 Ethyl Corporation Preparation of aniline from phenol and ammonia
JPS4831084B1 (enExample) 1970-09-04 1973-09-26
GB1344557A (en) 1972-06-23 1974-01-23 Mitsubishi Petrochemical Co Process for preparing 1,4-butanediol
JPS5543759B2 (enExample) 1972-06-28 1980-11-07
JPS506776A (enExample) 1973-05-28 1975-01-23
DE2455617C3 (de) 1974-11-23 1982-03-18 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von Butandiol und/oder Tetrahydrofuran über die Zwischenstufe des γ-Butyrolactons
DE2501499A1 (de) 1975-01-16 1976-07-22 Hoechst Ag Verfahren zur herstellung von butandiol-(1.4)
US4190495A (en) 1976-09-27 1980-02-26 Research Corporation Modified microorganisms and method of preparing and using same
US4301077A (en) 1980-12-22 1981-11-17 Standard Oil Company Process for the manufacture of 1-4-butanediol and tetrahydrofuran
IT1190783B (it) 1981-04-29 1988-02-24 Davy Mckee Oil & Chem Processo per l'idrogenolisi di esteri di acidi carbossilici
JPS60114197A (ja) 1983-11-25 1985-06-20 Agency Of Ind Science & Technol 微生物によるジカルボン酸の製造法
US4871667A (en) 1984-11-26 1989-10-03 Agency Of Industrial Science & Technology Process for preparing muconic acid
US4652685A (en) 1985-11-15 1987-03-24 General Electric Company Hydrogenation of lactones to glycols
US5168055A (en) 1986-06-11 1992-12-01 Rathin Datta Fermentation and purification process for succinic acid
US5143834A (en) 1986-06-11 1992-09-01 Glassner David A Process for the production and purification of succinic acid
ES2036188T3 (es) 1986-06-11 1993-05-16 Michigan Biotechnology Institute Un procedimiento para la produccion de acido succinico por fermentacion anaerobia.
US4698452A (en) 1986-10-02 1987-10-06 Institut Nationale De La Recherche Scientifique Ethylene light olefins from ethanol
KR890003714B1 (ko) 1987-03-26 1989-09-30 주식회사 미원 유전자 조작 미생물에 의한 l-페닐알라닌 제조방법
US5182199A (en) 1987-05-27 1993-01-26 Hartley Brian S Thermophilic ethanol production in a two-stage closed system
US4873392A (en) 1988-04-25 1989-10-10 Concordia University Catalytic conversion of aqueous ethanol to ethylene
US5219757A (en) 1988-04-27 1993-06-15 Daicel Chemical Industries, Ltd. Production of optically active 1,3-butanediol by asymmetric assimilation or reduction of 4-hydroxy-2-butanone
CA2062753C (en) 1989-04-27 2005-04-26 N. Robert Ward, Jr. Precipitate test for microorganisms
GB9014724D0 (en) * 1990-07-03 1990-08-22 Shell Int Research Process for the preparation of alpha,beta-olefinically unsaturated compounds
JPH05506983A (ja) 1990-03-09 1993-10-14 バスフ ケイ アンド エフ コーポレイション 天然長鎖アルコールの製造方法
US5192673A (en) 1990-04-30 1993-03-09 Michigan Biotechnology Institute Mutant strain of C. acetobutylicum and process for making butanol
US5079143A (en) 1990-05-02 1992-01-07 The Upjohn Company Method of indentifying compounds useful as antiparasitic drugs
DE69132472T2 (de) 1990-10-15 2001-03-15 Daicel Chemical Industries, Ltd. Verfahren zur Herstellung von optisch aktivem 1,3-Butandiol
US5173429A (en) 1990-11-09 1992-12-22 The Board Of Trustees Of The University Of Arkansas Clostridiumm ljungdahlii, an anaerobic ethanol and acetate producing microorganism
IL100572A (en) 1991-01-03 1997-01-10 Lepetit Spa Amides of antibiotic ge 2270 factors their preparation and pharmaceutical compositions containing them
US5416020A (en) 1992-09-29 1995-05-16 Bio-Technical Resources Lactobacillus delbrueckii ssp. bulgaricus strain and fermentation process for producing L-(+)-lactic acid
US6136577A (en) 1992-10-30 2000-10-24 Bioengineering Resources, Inc. Biological production of ethanol from waste gases with Clostridium ljungdahlii
US5807722A (en) 1992-10-30 1998-09-15 Bioengineering Resources, Inc. Biological production of acetic acid from waste gases with Clostridium ljungdahlii
FR2702492B1 (fr) 1993-03-12 1995-05-24 Rhone Poulenc Chimie Procédé de production par fermentation d'acide itaconique.
US5487987A (en) 1993-09-16 1996-01-30 Purdue Research Foundation Synthesis of adipic acid from biomass-derived carbon sources
US5521075A (en) 1994-12-19 1996-05-28 Michigan Biotechnology Institute Method for making succinic acid, anaerobiospirillum succiniciproducens variants for use in process and methods for obtaining variants
US5504004A (en) 1994-12-20 1996-04-02 Michigan Biotechnology Institute Process for making succinic acid, microorganisms for use in the process and methods of obtaining the microorganisms
US5700934A (en) 1995-03-01 1997-12-23 Dsm N.V. Process for the preparation of epsilon-caprolactam and epsilon-caprolactam precursors
US5478952A (en) 1995-03-03 1995-12-26 E. I. Du Pont De Nemours And Company Ru,Re/carbon catalyst for hydrogenation in aqueous solution
US5863782A (en) 1995-04-19 1999-01-26 Women's And Children's Hospital Synthetic mammalian sulphamidase and genetic sequences encoding same
US5686276A (en) 1995-05-12 1997-11-11 E. I. Du Pont De Nemours And Company Bioconversion of a fermentable carbon source to 1,3-propanediol by a single microorganism
FR2736927B1 (fr) 1995-07-18 1997-10-17 Rhone Poulenc Fibres & Polymer Enzymes a activite amidase, outils genetiques et microorganismes hotes permettant leur obtention et procede d'hydrolyse mettant en oeuvre lesdites enzymes
US5573931A (en) 1995-08-28 1996-11-12 Michigan Biotechnology Institute Method for making succinic acid, bacterial variants for use in the process, and methods for obtaining variants
US5770435A (en) 1995-11-02 1998-06-23 University Of Chicago Mutant E. coli strain with increased succinic acid production
US5869301A (en) 1995-11-02 1999-02-09 Lockhead Martin Energy Research Corporation Method for the production of dicarboxylic acids
EP0776973A1 (en) 1995-12-08 1997-06-04 Centrum Voor Plantenveredelings- En Reproduktieonderzoek Fatty aldehyde decarbonylase for transforming bacterial cells and plants
US5908924A (en) 1996-02-27 1999-06-01 Michigan State University Cloning and expression of the gene encoding thermoanaerobacter ethanolicus 39E secondary-alcohol dehydrogenase and enzyme biochemical characterization
US5958745A (en) 1996-03-13 1999-09-28 Monsanto Company Methods of optimizing substrate pools and biosynthesis of poly-β-hydroxybutyrate-co-poly-β-hydroxyvalerate in bacteria and plants
KR100387301B1 (ko) 1996-07-01 2003-06-12 바이오 엔지니어링 리소스 인코포레이티드 폐가스로부터의 생성물의 생물학적 제조방법
KR100459818B1 (ko) 1996-09-02 2004-12-03 이. 아이. 두퐁 드 느무르 앤드 컴퍼니 ε-카프로락탐의 제조방법
EP0977865A1 (en) 1997-02-13 2000-02-09 James Madison University Methods of making polyhydroxyalkanoates comprising 4-hydroxybutyrate monomer units
KR100516986B1 (ko) 1997-02-19 2005-09-26 코닌클리즈케 디에스엠 엔.브이. 6-아미노카프론산 유도체를 과열 수증기와 접촉시킴으로써 촉매 없이 카프로락탐을 제조하는 방법
US6274790B1 (en) 1997-04-14 2001-08-14 The University Of British Columbia Nucleic acids encoding a plant enzyme involved in very long chain fatty acid synthesis
KR19990013007A (ko) 1997-07-31 1999-02-25 박원훈 형질전환된 대장균 ss373(kctc 8818p)과 이를 이용한숙신산의 생산방법
JPH11103863A (ja) 1997-10-08 1999-04-20 Nippon Shokubai Co Ltd マレイン酸異性化酵素遺伝子
US6280986B1 (en) 1997-12-01 2001-08-28 The United States Of America As Represented By The Secretary Of Agriculture Stabilization of pet operon plasmids and ethanol production in bacterial strains lacking lactate dehydrogenase and pyruvate formate lyase activities
MY121380A (en) 1998-04-13 2006-01-28 Univ Georgia Pyruvate carboxylase overexpression for enhanced production of oxaloacetate-derived biochemicals in microbial cells
US20030087381A1 (en) 1998-04-13 2003-05-08 University Of Georgia Research Foundation, Inc. Metabolically engineered organisms for enhanced production of oxaloacetate-derived biochemicals
US6159738A (en) 1998-04-28 2000-12-12 University Of Chicago Method for construction of bacterial strains with increased succinic acid production
DE19820652A1 (de) 1998-05-08 1999-11-11 Basf Ag Kationische Rutheniumkomplexe, Verfahren zu ihrer Herstellung und ihre Verwendung
US6432686B1 (en) 1998-05-12 2002-08-13 E. I. Du Pont De Nemours And Company Method for the production of 1,3-propanediol by recombinant organisms comprising genes for vitamin B12 transport
US6444784B1 (en) 1998-05-29 2002-09-03 Exxonmobil Research & Engineering Company Wax crystal modifiers (LAW657)
US6187569B1 (en) 1998-07-02 2001-02-13 E. I. Du Pont De Nemours And Company Microbial production of terephthalic acid and isophthalic acid
EP1097222A1 (en) 1998-07-15 2001-05-09 E.I. Du Pont De Nemours And Company Tetrahydrofolate metabolism enzymes
DE19856136C2 (de) 1998-12-04 2002-10-24 Pasteur Institut Verfahren und Vorrichtung zur Selektion beschleunigter Proliferation lebender Zellen in Suspension
AU3482200A (en) 1999-02-02 2000-08-25 Bernhard Palsson Methods for identifying drug targets based on genomic sequence data
US6686310B1 (en) 1999-02-09 2004-02-03 E. I. Du Pont De Nemours And Company High surface area sol-gel route prepared hydrogenation catalysts
US6365376B1 (en) 1999-02-19 2002-04-02 E. I. Du Pont De Nemours And Company Genes and enzymes for the production of adipic acid intermediates
AU3516100A (en) 1999-03-05 2000-09-21 Monsanto Technology Llc Multigene expression vectors for the biosynthesis of products via multienzyme biological pathways
DE60029440T2 (de) 1999-05-21 2007-02-08 Cargill Dow LLC, Minnetonka Methoden und materialien zur synthese von organischen produkten
AU7093600A (en) 1999-08-30 2001-03-26 Wisconsin Alumni Research Foundation Production of 3-hydroxypropionic acid in recombinant organisms
US6852517B1 (en) 1999-08-30 2005-02-08 Wisconsin Alumni Research Foundation Production of 3-hydroxypropionic acid in recombinant organisms
US6660857B2 (en) 2000-02-03 2003-12-09 Dsm N.V. Process for the preparation of ε-caprolactam
US6878861B2 (en) 2000-07-21 2005-04-12 Washington State University Research Foundation Acyl coenzyme A thioesterases
ATE332390T1 (de) 2000-07-25 2006-07-15 Emmaus Foundation Inc Verfahren zur produktionssteigerung von die fermentativen erzeugnung von ethanol
US7186541B2 (en) 2000-11-20 2007-03-06 Cargill, Incorporated 3-hydroxypropionic acid and other organic compounds
CA2430270A1 (en) 2000-11-22 2002-05-30 Cargill Dow Polymers, Llc Methods and materials for the synthesis of organic products
CN1358841A (zh) 2000-12-11 2002-07-17 云南省微生物研究所 云南链霉菌
EP1354955A4 (en) 2000-12-28 2005-01-05 Toyota Motor Co Ltd PROCESS FOR PREPARING PRENYL ALCOHOL
JP4776146B2 (ja) 2001-01-10 2011-09-21 ザ・ペン・ステート・リサーチ・ファンデーション 細胞代謝をモデル化する方法及びシステム
US7127379B2 (en) 2001-01-31 2006-10-24 The Regents Of The University Of California Method for the evolutionary design of biochemical reaction networks
CA2439260C (en) 2001-03-01 2012-10-23 The Regents Of The University Of California Models and methods for determining systemic properties of regulated reaction networks
US6743610B2 (en) 2001-03-30 2004-06-01 The University Of Chicago Method to produce succinic acid from raw hydrolysates
BR0209491A (pt) 2001-05-07 2004-10-13 Cargil Inc Processo para preparar ácidos carboxìlicos e derivados destes
JP4630486B2 (ja) 2001-05-28 2011-02-09 ダイセル化学工業株式会社 新規な(r)−2,3−ブタンジオール脱水素酵素、その製造方法、及びこれを利用した光学活性アルコールの製造方法
WO2003010322A1 (en) 2001-07-20 2003-02-06 Youming Zhang Improved rect or recet cloning and subcloning method
CA2356540A1 (en) 2001-08-30 2003-02-28 Emory University Expressed dna sequences involved in mitochondrial functions
MXPA04004194A (es) 2001-11-02 2005-03-31 Rice University Sistema de recirculacion para la manipulacion de disponibilidad de nadh intracelular.
EP1575881B1 (en) 2002-01-18 2009-05-27 Novozymes A/S Alanine 2,3- aminomutase
US20070117191A1 (en) 2002-02-06 2007-05-24 Harumi Kamachi Reductase gene for alpha-substituted-alpha, beta-unsaturated carbonyl compound
US20030224363A1 (en) 2002-03-19 2003-12-04 Park Sung M. Compositions and methods for modeling bacillus subtilis metabolism
CA2480216A1 (en) 2002-03-29 2003-10-09 Genomatica, Inc. Human metabolic models and methods
JPWO2003095651A1 (ja) 2002-05-10 2005-09-15 協和醗酵工業株式会社 メバロン酸の製造方法
US7856317B2 (en) 2002-06-14 2010-12-21 Genomatica, Inc. Systems and methods for constructing genomic-based phenotypic models
EP1513946B1 (en) 2002-06-14 2007-05-16 DSM IP Assets B.V. Polypeptides having alpha-h-alpha amino acid amide racemase activity and nucleic acids encoding the same
US7826975B2 (en) 2002-07-10 2010-11-02 The Penn State Research Foundation Method for redesign of microbial production systems
JP4418793B2 (ja) 2002-07-10 2010-02-24 ザ ペン ステート リサーチ ファウンデーション 遺伝子ノックアウト戦略を決定する方法
AU2003253949A1 (en) 2002-07-15 2004-02-02 Kosan Biosciences, Inc. Metabolic pathways for starter units in polyketide biosynthesis
US7371558B2 (en) 2002-10-04 2008-05-13 E.I. Du Pont De Nemours And Company Process for the biological production of 1,3-propanediol with high yield
CA2500761C (en) 2002-10-15 2012-11-20 Bernhard O. Palsson Methods and systems to identify operational reaction pathways
WO2004044210A2 (en) 2002-11-06 2004-05-27 University Of Florida Materials and methods for the efficient production of acetate and other products
WO2004056963A2 (en) 2002-12-16 2004-07-08 E.I. Du Pont De Nemours And Company B12 dependent dehydratases with improved reaction kinetics
CA2512815A1 (en) 2003-01-13 2004-07-29 Cargill, Incorporated Method for making industrial chemicals
WO2004074495A1 (ja) 2003-02-24 2004-09-02 Research Institute Of Innovative Technology For The Earth 微生物による高効率水素製造方法
RU2268300C2 (ru) 2003-04-07 2006-01-20 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИЙ, ОБЛАДАЮЩИХ ПОВЫШЕННОЙ ЭКСПРЕССИЕЙ ГЕНА pckA
JP4451393B2 (ja) 2003-07-29 2010-04-14 財団法人地球環境産業技術研究機構 コリネ型細菌形質転換体及びそれを用いるジカルボン酸の製造方法
US7927859B2 (en) 2003-08-22 2011-04-19 Rice University High molar succinate yield bacteria by increasing the intracellular NADH availability
JP4619291B2 (ja) 2003-09-17 2011-01-26 三菱化学株式会社 非アミノ有機酸の製造方法
EP1664286A1 (en) 2003-09-18 2006-06-07 Ciba SC Holding AG Alcohol dehydrogenases with increased solvent and temperature stability
FR2862068B1 (fr) 2003-11-06 2007-10-12 Metabolic Explorer Sa Souches de microorganismes optimisees pour des voies de biosyntheses consommatrices de nadph
US7244610B2 (en) 2003-11-14 2007-07-17 Rice University Aerobic succinate production in bacteria
FR2864967B1 (fr) 2004-01-12 2006-05-19 Metabolic Explorer Sa Microorganisme evolue pour la production de 1,2-propanediol
AU2005205188B2 (en) 2004-01-19 2010-11-11 Genomatica, Inc. Biochemical synthesis of 6-amino caproic acid
US7608700B2 (en) 2004-03-08 2009-10-27 North Carolina State University Lactobacillus acidophilus nucleic acid sequences encoding stress-related proteins and uses therefor
DE102004031177A1 (de) 2004-06-29 2006-01-19 Henkel Kgaa Neue Geruchsstoffe bildende Genprodukte von Bacillus licheniformis und darauf aufbauende verbesserte biotechnologische Produktionsverfahren
US7262046B2 (en) 2004-08-09 2007-08-28 Rice University Aerobic succinate production in bacteria
JP4771437B2 (ja) 2004-08-27 2011-09-14 ライス ユニバーシティー 増加したコハク酸産生を有する変異E.coli株
US8604180B2 (en) 2004-09-09 2013-12-10 Research Institute Of Innovative Technology For The Earth DNA fragment having promoter function
CN101023178A (zh) 2004-09-17 2007-08-22 莱斯大学 高琥珀酸产出细菌
US7569380B2 (en) 2004-12-22 2009-08-04 Rice University Simultaneous anaerobic production of isoamyl acetate and succinic acid
JP2006204255A (ja) 2005-01-31 2006-08-10 Canon Inc アセチル−CoAアシルトランスフェラーゼ遺伝子破壊ポリヒドロキシアルカノエート生産菌、またこれを利用したポリヒドロキシアルカノエート生産方法
WO2006109312A2 (en) 2005-04-15 2006-10-19 Vascular Biogenics Ltd. Compositions containing beta 2-glycoprotein i-derived peptides for the prevention and/or treatment of vascular disease
US8187842B2 (en) 2005-06-20 2012-05-29 Archer Daniels Midland Company Altered glyoxylate shunt for improved production of aspartate-derived amino acids and chemicals
KR100676160B1 (ko) 2005-08-19 2007-02-01 한국과학기술원 말릭효소를 코딩하는 유전자로 형질전환된 재조합 미생물 및 이를 이용한 숙신산의 제조방법
KR100679638B1 (ko) 2005-08-19 2007-02-06 한국과학기술원 포메이트 디하이드로게나제 d 또는 e를 코딩하는 유전자로 형질전환된 미생물 및 이를 이용한 숙신산의 제조방법
AU2006287257A1 (en) 2005-09-09 2007-03-15 Genomatica, Inc. Methods and organisms for the growth-coupled production of succinate
US9297028B2 (en) 2005-09-29 2016-03-29 Butamax Advanced Biofuels Llc Fermentive production of four carbon alcohols
EP3301182B1 (en) 2005-10-26 2020-03-18 Butamax (TM) Advanced Biofuels LLC Fermentative production of four carbon alcohols
GB2433260A (en) * 2005-12-16 2007-06-20 Mologic Ltd A selectable decarboxylase marker
NZ572363A (en) 2006-05-01 2012-12-21 Univ Florida Ethanol production in non-recombinant bacterium comprising a mutation that affects nadh production
US8828704B2 (en) 2006-05-02 2014-09-09 Butamax Advanced Biofuels Llc Fermentive production of four carbon alcohols
US8962298B2 (en) 2006-05-02 2015-02-24 Butamax Advanced Biofuels Llc Recombinant host cell comprising a diol dehydratase
DE102006025821A1 (de) 2006-06-02 2007-12-06 Degussa Gmbh Ein Enzym zur Herstellung von Mehylmalonatsemialdehyd oder Malonatsemialdehyd
RU2311231C1 (ru) 2006-08-15 2007-11-27 ООО "Объединенный центр исследований и разработок" Катализатор для получения эфиров акриловой кислоты по реакции метатезиса диалкилмалеатов (варианты) и каталитическая композиция на его основе
EP2064321B1 (en) 2006-08-30 2016-03-09 Cargill, Incorporated Beta-alanine/alpha-ketoglutarate aminotransferase for 3-hydroxypropionic acid production
US8017364B2 (en) 2006-12-12 2011-09-13 Butamax(Tm) Advanced Biofuels Llc Solvent tolerant microorganisms
EP2121949B1 (en) 2006-12-21 2013-05-08 GEVO, Inc. Butanol production by metabolically engineered yeast
CA2675026A1 (en) 2007-01-12 2008-07-24 The Regents Of The University Of Colorado, A Body Corporate Compositions and methods for enhancing tolerance for the production of organic chemicals produced by microorganisms
TWI568847B (zh) 2007-03-16 2017-02-01 奇諾麥提卡公司 用於1,4-丁二醇及其前驅物之生物合成的組合物及方法
EP2147111A4 (en) 2007-04-18 2010-06-23 Gevo Inc MANIPULATED MICROORGANISMS FOR THE MANUFACTURE OF ISOPROPANOL
US8426174B2 (en) 2007-05-02 2013-04-23 Butamax(Tm) Advanced Biofuels Llc Method for the production of 2-butanol
US20080274522A1 (en) 2007-05-02 2008-11-06 Bramucci Michael G Method for the production of 2-butanone
EP2152852A2 (en) 2007-05-17 2010-02-17 Tetravitae Bioscience, Inc. Methods and compositions for producing solvents
CN104212844A (zh) 2007-06-01 2014-12-17 索拉兹米公司 在微生物中生产油
BRPI0812515A2 (pt) 2007-06-15 2014-12-30 Evonik Degussa Gmbh Micro-organismo com sistema de vitamina b12 desregulado
EP2017344A1 (en) 2007-07-20 2009-01-21 Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO Production of itaconic acid
US20100205857A1 (en) 2007-07-23 2010-08-19 Einte-Karst Dijk Butanol production in a eukaryotic cell
CN101362799A (zh) * 2007-08-10 2009-02-11 中国科学院上海生命科学研究院 调控植物株高的基因及其应用
US7947483B2 (en) 2007-08-10 2011-05-24 Genomatica, Inc. Methods and organisms for the growth-coupled production of 1,4-butanediol
KR101042242B1 (ko) 2007-09-07 2011-06-17 한국과학기술원 1,4-부탄디올 생성능을 가지는 변이체 및 이를 이용한1,4-부탄디올의 제조방법
CN101903530A (zh) 2007-10-12 2010-12-01 加利福尼亚大学董事会 被改造以产生异丙醇的微生物
US8183028B2 (en) 2007-12-21 2012-05-22 Ls9, Inc. Methods and compositions for producing olefins
CN107090424A (zh) 2008-01-22 2017-08-25 基因组股份公司 利用合成气或其它气态碳源和甲醇的方法和有机体
WO2009103026A1 (en) 2008-02-15 2009-08-20 Gevo, Inc. Engineered microorganisms for producing isopropanol
CN102026960B (zh) 2008-03-11 2014-07-16 帝斯曼知识产权资产管理有限公司 从5-甲酰缬草酸制备6-氨基己酸
CN109468348B (zh) 2008-03-11 2023-05-16 基因组股份公司 己二酸酯或硫代酯合成
PL2265709T3 (pl) 2008-03-27 2018-05-30 Genomatica, Inc. Mikroorganizmy do produkcji kwasu adypinowego i innych związków
WO2009131040A1 (ja) 2008-04-25 2009-10-29 財団法人地球環境産業技術研究機構 イソプロパノール生産能を有するコリネ型細菌の形質転換体
WO2009155382A1 (en) 2008-06-17 2009-12-23 Genomatica, Inc. Microorganisms and methods for the biosynthesis of fumarate, malate, and acrylate
PT2304040T (pt) 2008-07-04 2017-11-21 Scientist Of Fortune Sa Produção de alcenos por descarboxilação enzimática de ácidos 3-hidroxi-alcanoicos
WO2010022763A1 (en) 2008-08-25 2010-03-04 Metabolic Explorer Method for the preparation of 2-hydroxy-isobutyrate
US8357826B2 (en) 2008-10-16 2013-01-22 Karl Kharas Methods and apparatus for synthesis of alcohols from syngas
US8445248B2 (en) 2008-11-17 2013-05-21 Board Of Regents Of The Nevada System Of Higher Education On Behalf Of The University Of Nevada, Reno Hydrocarbon-forming oxidative decarbonylase enzyme, hydrocarbons produced thereby, and method of use
CN102317437B (zh) 2008-12-12 2013-08-21 麦特波力克斯公司 用于制备聚(5-羟基戊酸)和5碳化合物的绿色工艺和组合物
CA2746952A1 (en) 2008-12-16 2010-06-24 Genomatica, Inc. Microorganisms and methods for conversion of syngas and other carbon sources to useful products
BRPI1010581A2 (pt) 2009-06-04 2016-11-08 Genomatica Inc micro-organismos para a produção de 1,4-butanodiol e métodos relacionados
EP2467490A1 (en) 2009-08-21 2012-06-27 Mascoma Corporation Production of propanols, alcohols, and polyols in consolidated bioprocessing organisms
US20120276606A1 (en) 2009-10-30 2012-11-01 Daicel Corporation Recombinant microorganisms with 1,3-butanediol-producing function and uses thereof
CN102753698A (zh) 2009-12-10 2012-10-24 基因组股份公司 合成气或其他气态碳源和甲醇转化为1,3-丁二醇的方法和有机体
EP2336341A1 (en) 2009-12-21 2011-06-22 Philippe Marliere Method for producing an alkene comprising the step of converting an alcohol by an enzymatic dehydration step
KR20190006103A (ko) * 2010-05-05 2019-01-16 게노마티카 인코포레이티드 부타디엔을 생합성하기 위한 미생물 및 방법
US9169486B2 (en) * 2011-06-22 2015-10-27 Genomatica, Inc. Microorganisms for producing butadiene and methods related thereto
CN103890185A (zh) * 2011-08-19 2014-06-25 基因组股份公司 用于生产2,4-戊二烯酸、丁二烯、丙烯、1,3-丁二醇和相关醇的微生物和方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009111513A1 (en) * 2008-03-03 2009-09-11 Joule Biotechnologies, Inc. Engineered co2 fixing microorganisms producing carbon-based products of interest
CN101329232A (zh) * 2008-07-28 2008-12-24 中国烟草总公司郑州烟草研究院 基于热裂解-气相色谱质谱联用技术的烟用香原料筛选方法

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
JPN6015036535; Environ Sci Technol, 1989, vol.23, p.610-614 *
JPN6015036537; 1,3-BUTADIENE, Scorecard Goodguide, 2001 [検索日:2015年9月1日] *
JPN6016029396; Anal. Chem. 2003, vol.75, p.4441-4451 *

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015042711A (ja) * 2013-08-26 2015-03-05 住友ゴム工業株式会社 乗用車タイヤ用キャップトレッドゴム組成物、乗用車タイヤ用キャップトレッドゴム、及び乗用車用空気入りタイヤ
JP2021177785A (ja) * 2013-12-05 2021-11-18 ジェノマティカ, インコーポレイテッド 脂肪アミンの微生物生産方法
US11814660B2 (en) 2013-12-05 2023-11-14 Genomatica, Inc. Recombinant microorganisms for the production of fatty amines
JP2017088708A (ja) * 2015-11-06 2017-05-25 住友ベークライト株式会社 ポリアミド樹脂およびポリアミド樹脂の製造方法
WO2018030526A1 (ja) * 2016-08-12 2018-02-15 旭硝子株式会社 形質転換体および3-ヒドロキシプロピオン酸の製造方法
WO2019107516A1 (ja) 2017-11-30 2019-06-06 東レ株式会社 3-ヒドロキシアジピン酸、α-ヒドロムコン酸および/またはアジピン酸を生産するための遺伝子改変微生物および当該化学品の製造方法
WO2020230719A1 (ja) 2019-05-10 2020-11-19 東レ株式会社 3-ヒドロキシアジピン酸、α-ヒドロムコン酸および/またはアジピン酸を生産するための遺伝子改変微生物および当該化学品の製造方法
JPWO2020230718A1 (enExample) * 2019-05-10 2020-11-19
WO2020230718A1 (ja) 2019-05-10 2020-11-19 東レ株式会社 3-ヒドロキシアジピン酸、α-ヒドロムコン酸および/またはアジピン酸を生産するための遺伝子改変微生物および当該化学品の製造方法
JP7530554B2 (ja) 2019-05-10 2024-08-08 東レ株式会社 3-ヒドロキシアジピン酸、α-ヒドロムコン酸および/またはアジピン酸を生産するための遺伝子改変微生物および当該化学品の製造方法
WO2022102635A1 (ja) 2020-11-11 2022-05-19 東レ株式会社 3-ヒドロキシアジピン酸および/またはα-ヒドロムコン酸を生産するための遺伝子改変微生物および当該化学品の製造方法

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