SG10201503501TA - Microorganisms and methods for the biosynthesis of butadiene - Google Patents

Microorganisms and methods for the biosynthesis of butadiene

Info

Publication number
SG10201503501TA
SG10201503501TA SG10201503501TA SG10201503501TA SG10201503501TA SG 10201503501T A SG10201503501T A SG 10201503501TA SG 10201503501T A SG10201503501T A SG 10201503501TA SG 10201503501T A SG10201503501T A SG 10201503501TA SG 10201503501T A SG10201503501T A SG 10201503501TA
Authority
SG
Singapore
Prior art keywords
biosynthesis
microorganisms
butadiene
methods
Prior art date
Application number
SG10201503501TA
Inventor
Mark J Burk
Anthony P Burgard
Jun Sun
Robin E Osterhout
Priti Pharkya
Original Assignee
Genomatica Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genomatica Inc filed Critical Genomatica Inc
Publication of SG10201503501TA publication Critical patent/SG10201503501TA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/02Preparation of hydrocarbons or halogenated hydrocarbons acyclic
    • C12P5/026Unsaturated compounds, i.e. alkenes, alkynes or allenes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C11/00Aliphatic unsaturated hydrocarbons
    • C07C11/12Alkadienes
    • C07C11/16Alkadienes with four carbon atoms
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F136/00Homopolymers of compounds having one or more unsaturated aliphatic radicals, at least one having two or more carbon-to-carbon double bonds
    • C08F136/02Homopolymers of compounds having one or more unsaturated aliphatic radicals, at least one having two or more carbon-to-carbon double bonds the radical having only two carbon-to-carbon double bonds
    • C08F136/04Homopolymers of compounds having one or more unsaturated aliphatic radicals, at least one having two or more carbon-to-carbon double bonds the radical having only two carbon-to-carbon double bonds conjugated
    • C08F136/06Butadiene
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • C12N1/16Yeasts; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • C12N1/16Yeasts; Culture media therefor
    • C12N1/18Baker's yeast; Brewer's yeast
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Botany (AREA)
  • Polymers & Plastics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
SG10201503501TA 2010-05-05 2011-05-04 Microorganisms and methods for the biosynthesis of butadiene SG10201503501TA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33181210P 2010-05-05 2010-05-05

Publications (1)

Publication Number Publication Date
SG10201503501TA true SG10201503501TA (en) 2015-06-29

Family

ID=45064763

Family Applications (2)

Application Number Title Priority Date Filing Date
SG2012081519A SG185432A1 (en) 2010-05-05 2011-05-04 Microorganisms and methods for the biosynthesis of butadiene
SG10201503501TA SG10201503501TA (en) 2010-05-05 2011-05-04 Microorganisms and methods for the biosynthesis of butadiene

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG2012081519A SG185432A1 (en) 2010-05-05 2011-05-04 Microorganisms and methods for the biosynthesis of butadiene

Country Status (13)

Country Link
US (5) US8580543B2 (en)
EP (1) EP2566969B1 (en)
JP (3) JP5911847B2 (en)
KR (3) KR20180005263A (en)
CN (2) CN103080324B (en)
AU (2) AU2011248182A1 (en)
BR (1) BR112012028049A2 (en)
CA (1) CA2797409C (en)
CO (1) CO6630182A2 (en)
MX (1) MX336229B (en)
SG (2) SG185432A1 (en)
TW (2) TWI575072B (en)
WO (1) WO2011140171A2 (en)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8129154B2 (en) 2008-06-17 2012-03-06 Genomatica, Inc. Microorganisms and methods for the biosynthesis of fumarate, malate, and acrylate
AU2009327490A1 (en) 2008-12-16 2011-07-28 Genomatica, Inc. Microorganisms and methods for conversion of syngas and other carbon sources to useful products
WO2010144746A2 (en) * 2009-06-10 2010-12-16 Genomatica, Inc. Microorganisms and methods for carbon-efficient biosynthesis of mek and 2-butanol
CN109136161A (en) 2009-12-10 2019-01-04 基因组股份公司 Synthesis gas or other gaseous carbon sources and methanol are converted into the method and organism of 1,3 butylene glycol
US8445244B2 (en) 2010-02-23 2013-05-21 Genomatica, Inc. Methods for increasing product yields
CN103080324B (en) * 2010-05-05 2019-03-08 基因组股份公司 Microorganism and method for butadiene biosynthesis
BR112013001635A2 (en) * 2010-07-26 2016-05-24 Genomatica Inc microorganism and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene
MY162964A (en) * 2011-02-02 2017-07-31 Genomatica Inc Microorganisms and methods for the biosynthesis of butadiene
CN107254492A (en) 2011-06-17 2017-10-17 英威达技术有限责任公司 The method for producing 1,3 butadiene
US9422578B2 (en) 2011-06-17 2016-08-23 Invista North America S.A.R.L. Methods for biosynthesizing 1,3 butadiene
US9169486B2 (en) * 2011-06-22 2015-10-27 Genomatica, Inc. Microorganisms for producing butadiene and methods related thereto
CN103890185A (en) * 2011-08-19 2014-06-25 基因组股份公司 Microorganisms and methods for producing 2,4-pentadienoate, butadiene, propylene, 1,3-butanediol and related alcohols
US9169496B2 (en) 2011-10-19 2015-10-27 Scientist of Fortune, S.A. Method for the enzymatic production of butadiene
US8415136B1 (en) 2011-11-09 2013-04-09 Amyris, Inc. Production of acetyl-coenzyme a derived isoprenoids
BR112014012999A2 (en) * 2011-12-02 2017-06-13 Invista Tech Sarl butadiene biosynthesis method
WO2013090915A1 (en) 2011-12-16 2013-06-20 Braskem S.A. Modified microorganisms and methods of making butadiene using same
US9873895B2 (en) 2011-12-20 2018-01-23 Scientist Of Fortune S.A. Production of 1,3-dienes by enzymatic conversion of 3-hydroxyalk 4-enoates and/or 3-phosphonoxyalk-4-enoates
WO2013130426A1 (en) * 2012-03-02 2013-09-06 Codexis, Inc. Recombinant host cells and processes for producing 1,3-butadiene through a 5-hydroxypent-3-enoate intermediate
WO2013130481A1 (en) * 2012-03-02 2013-09-06 Codexis, Inc. Recombinant host cells and processes for producing 1,3-butadiene through a crotonol intermediate
US9803209B2 (en) 2012-05-18 2017-10-31 Novozymes A/S Bacterial mutants with improved transformation efficiency
EP2861745A2 (en) * 2012-06-15 2015-04-22 Invista Technologies S.à.r.l. Methods for biosynthesizing 1,3 butadiene
CN104520431A (en) * 2012-06-18 2015-04-15 布拉斯科南美公司 Modified microorganisms and methods of co-producing butadiene with 1-propanol and/or 1,2-propanediol
BR112015004488A2 (en) * 2012-08-28 2018-11-21 Braskem Sa method of co-producing a terpene and at least one co-product from a fermentable carbon source
US20150218567A1 (en) 2012-09-27 2015-08-06 Novozymes A/S Bacterial Mutants with Improved Transformation Efficiency
US20140134687A1 (en) * 2012-10-02 2014-05-15 Braskem S/A Ap 09 Modified microorganisms and methods of using same for producing butadiene and succinate
WO2014063156A2 (en) * 2012-10-19 2014-04-24 Braskem S/A Ap 09 Modified microorganisms and methods of using same for producing butadiene and one or more of 1,3-butanediol, 1,4-butanediol, and/or 1,3-propanediol
US9932611B2 (en) * 2012-10-22 2018-04-03 Genomatica, Inc. Microorganisms and methods for enhancing the availability of reducing equivalents in the presence of methanol, and for producing succinate related thereto
EP2920314A1 (en) * 2012-11-13 2015-09-23 Global Bioenergies Process for the enzymatic preparation of isoprene from isoprenol
US10066223B2 (en) 2012-11-21 2018-09-04 The Regents Of The University Of California Nucleic acids useful for integrating into and gene expression in hyperthermophilic acidophilic Archaea
CN104903455A (en) 2012-11-28 2015-09-09 英威达技术有限责任公司 Methods for biosynthesis of isobutene
JP6304924B2 (en) * 2012-11-29 2018-04-04 住友ゴム工業株式会社 Rubber composition for sidewall and pneumatic tire
WO2014089025A1 (en) * 2012-12-04 2014-06-12 Genomatica, Inc. Increased yields of biosynthesized products
WO2014106122A1 (en) * 2012-12-31 2014-07-03 Genomatica, Inc. Compositions and methods for bio-butadiene production screening
JP2014155455A (en) * 2013-02-15 2014-08-28 Sekisui Chem Co Ltd RECOMBINANT CELLS AND METHOD FOR PRODUCING CROTONYL-CoA OR CROTYL ALCOHOL
JP2014161252A (en) * 2013-02-22 2014-09-08 Sekisui Chem Co Ltd Recombinant cells
US20160040172A1 (en) 2013-03-15 2016-02-11 Genomatica, Inc. Microorganisms and methods for producing butadiene and related compounds by formate assimilation
CN105518130A (en) 2013-06-21 2016-04-20 丹尼斯科美国公司 Compositions and methods for clostridial transformation
US10294496B2 (en) 2013-07-19 2019-05-21 Invista North America S.A.R.L. Methods for biosynthesizing 1,3 butadiene
EP3030667A2 (en) 2013-08-05 2016-06-15 Invista Technologies S.a r.l. Methods for biosynthesis of isoprene
WO2015021059A1 (en) 2013-08-05 2015-02-12 INVISTA North America S.á r.l. Methods for biosynthesis of isobutene
PL3077501T3 (en) 2013-12-03 2022-01-31 Genomatica, Inc. Microorganisms and methods for improving product yields on methanol using acetyl-coa synthesis
CN106062178B (en) 2013-12-27 2021-07-27 基因组股份公司 Methods and organisms with increased carbon flux efficiency
WO2015147644A1 (en) * 2014-03-27 2015-10-01 Photanol B.V. Erythritol production in cyanobacteria
US20170152531A1 (en) * 2014-06-16 2017-06-01 North America S.A.R.L. Process for producing glutarate and glutaric acid methyl ester
WO2016007365A1 (en) 2014-07-11 2016-01-14 Genomatica, Inc. Microorganisms and methods for the production of butadiene using acetyl-coa
DK3194604T3 (en) 2014-09-18 2020-05-25 Genomatica Inc NON-NATURAL MICROBIAL ORGANISMS WITH IMPROVED ENERGY EFFICIENCY
CN104298866B (en) * 2014-09-30 2017-06-06 杭州电子科技大学 Reacting furnace dynamic modelling method in a kind of Claus sulphur recovery process
JP6432774B2 (en) * 2014-12-25 2018-12-05 江南化工株式会社 Cell activator
CN107404882A (en) 2015-02-27 2017-11-28 白狗实验室有限公司 For producing acetone, isopropanol, butyric acid, other biological product and its mixotrophism fermentation process of mixture
WO2016160812A1 (en) * 2015-03-31 2016-10-06 White Dog Labs, Inc. Method of producing bioproducts
CN107750276A (en) * 2015-04-09 2018-03-02 基因组股份公司 For improving the engineered microorganisms and method of crotons alcohol production
BR112017025554B1 (en) 2015-05-30 2024-03-12 Genomatica, Inc. COMPOSITION, AND, METHOD FOR PRODUCING A POLYMER, RESIN OR ARTICLE OF MANUFACTURING
WO2017064606A1 (en) * 2015-10-12 2017-04-20 Reliance Industries Limited Process for preparation of 1,3-butadiene
CN115322261A (en) 2015-10-30 2022-11-11 基因组股份公司 Methanol dehydrogenase fusion protein
GB201605354D0 (en) 2016-03-30 2016-05-11 Zuvasyntha Ltd Modified enzyme
US11498062B2 (en) 2016-09-30 2022-11-15 Regents Of The University Of Minnesota Phosphorus-containing solid catalysts and reactions catalyzed thereby, including synthesis of p-xylene
JP6317498B2 (en) * 2017-03-22 2018-04-25 住友ゴム工業株式会社 Rubber composition for tread for studless tire and studless tire
JP6317497B2 (en) * 2017-03-22 2018-04-25 住友ゴム工業株式会社 Tread rubber composition and pneumatic tire
US11634733B2 (en) 2017-06-30 2023-04-25 Inv Nylon Chemicals Americas, Llc Methods, materials, synthetic hosts and reagents for the biosynthesis of hydrocarbons and derivatives thereof
US11162115B2 (en) 2017-06-30 2021-11-02 Inv Nylon Chemicals Americas, Llc Methods, synthetic hosts and reagents for the biosynthesis of hydrocarbons
US11505809B2 (en) 2017-09-28 2022-11-22 Inv Nylon Chemicals Americas Llc Organisms and biosynthetic processes for hydrocarbon synthesis
US20210079334A1 (en) 2018-01-30 2021-03-18 Genomatica, Inc. Fermentation systems and methods with substantially uniform volumetric uptake rate of a reactive gaseous component
US11541105B2 (en) 2018-06-01 2023-01-03 The Research Foundation For The State University Of New York Compositions and methods for disrupting biofilm formation and maintenance
CA3103377A1 (en) 2018-06-26 2020-01-02 Genomatica, Inc. Engineered microorganisms with g3p---> 3pg enzyme and/or fructose-1,6-bisphosphatase including those having synthetic or enhanced methylotrophy
US20220258100A1 (en) * 2019-07-16 2022-08-18 San Diego State University (SDSU) Foundation, dba San Diego State University Research Foundation Products of manufacture and methods for methane capturing using biofiltration

Family Cites Families (158)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3513209A (en) 1968-08-19 1970-05-19 Du Pont Method of making 1,4-cyclohexadiene
US4076948A (en) 1968-10-10 1978-02-28 El Paso Products Company Process for treatment of adipic acid mother liquor
GB1230276A (en) 1968-12-09 1971-04-28
US3965182A (en) 1969-10-02 1976-06-22 Ethyl Corporation Preparation of aniline from phenol and ammonia
JPS4831084B1 (en) 1970-09-04 1973-09-26
GB1344557A (en) 1972-06-23 1974-01-23 Mitsubishi Petrochemical Co Process for preparing 1,4-butanediol
JPS5543759B2 (en) 1972-06-28 1980-11-07
DE2455617C3 (en) 1974-11-23 1982-03-18 Basf Ag, 6700 Ludwigshafen Process for the production of butanediol and / or tetrahydrofuran via the intermediate stage of γ-butyrolactone
DE2501499A1 (en) 1975-01-16 1976-07-22 Hoechst Ag PROCESS FOR THE PRODUCTION OF BUTANDIOL- (1.4)
US4190495A (en) 1976-09-27 1980-02-26 Research Corporation Modified microorganisms and method of preparing and using same
US4301077A (en) 1980-12-22 1981-11-17 Standard Oil Company Process for the manufacture of 1-4-butanediol and tetrahydrofuran
JPS60114197A (en) 1983-11-25 1985-06-20 Agency Of Ind Science & Technol Preparation of dicarboxylic acid by bacterium
US4871667A (en) 1984-11-26 1989-10-03 Agency Of Industrial Science & Technology Process for preparing muconic acid
US4652685A (en) 1985-11-15 1987-03-24 General Electric Company Hydrogenation of lactones to glycols
US5168055A (en) 1986-06-11 1992-12-01 Rathin Datta Fermentation and purification process for succinic acid
EP0249773B1 (en) 1986-06-11 1992-12-16 Michigan Biotechnology Institute A process for the production of succinic acid by anaerobic fermentation
US5143834A (en) 1986-06-11 1992-09-01 Glassner David A Process for the production and purification of succinic acid
US5182199A (en) 1987-05-27 1993-01-26 Hartley Brian S Thermophilic ethanol production in a two-stage closed system
JPH01195596A (en) 1988-01-30 1989-08-07 Casio Comput Co Ltd Price tag system
EP0633319B1 (en) 1988-04-27 1999-03-17 Daicel Chemical Industries, Ltd. Process for producing optically active 1,3-butanediol
EP0470172B1 (en) 1989-04-27 1995-06-28 BioControl Systems, Incorporated Precipitate test for microorganisms
US5192673A (en) 1990-04-30 1993-03-09 Michigan Biotechnology Institute Mutant strain of C. acetobutylicum and process for making butanol
US5079143A (en) 1990-05-02 1992-01-07 The Upjohn Company Method of indentifying compounds useful as antiparasitic drugs
EP0769557B1 (en) 1990-10-15 2000-11-15 Daicel Chemical Industries, Ltd. Process for producing optically active 1,3-butanediol
US5173429A (en) 1990-11-09 1992-12-22 The Board Of Trustees Of The University Of Arkansas Clostridiumm ljungdahlii, an anaerobic ethanol and acetate producing microorganism
IL100572A (en) 1991-01-03 1997-01-10 Lepetit Spa Amides of antibiotic ge 2270 factors their preparation and pharmaceutical compositions containing them
US5416020A (en) 1992-09-29 1995-05-16 Bio-Technical Resources Lactobacillus delbrueckii ssp. bulgaricus strain and fermentation process for producing L-(+)-lactic acid
US6136577A (en) 1992-10-30 2000-10-24 Bioengineering Resources, Inc. Biological production of ethanol from waste gases with Clostridium ljungdahlii
US5807722A (en) 1992-10-30 1998-09-15 Bioengineering Resources, Inc. Biological production of acetic acid from waste gases with Clostridium ljungdahlii
FR2702492B1 (en) 1993-03-12 1995-05-24 Rhone Poulenc Chimie Production process by fermentation of itaconic acid.
US5487987A (en) 1993-09-16 1996-01-30 Purdue Research Foundation Synthesis of adipic acid from biomass-derived carbon sources
US5521075A (en) 1994-12-19 1996-05-28 Michigan Biotechnology Institute Method for making succinic acid, anaerobiospirillum succiniciproducens variants for use in process and methods for obtaining variants
US5504004A (en) 1994-12-20 1996-04-02 Michigan Biotechnology Institute Process for making succinic acid, microorganisms for use in the process and methods of obtaining the microorganisms
US5700934A (en) 1995-03-01 1997-12-23 Dsm N.V. Process for the preparation of epsilon-caprolactam and epsilon-caprolactam precursors
US5478952A (en) 1995-03-03 1995-12-26 E. I. Du Pont De Nemours And Company Ru,Re/carbon catalyst for hydrogenation in aqueous solution
US5863782A (en) 1995-04-19 1999-01-26 Women's And Children's Hospital Synthetic mammalian sulphamidase and genetic sequences encoding same
US5686276A (en) 1995-05-12 1997-11-11 E. I. Du Pont De Nemours And Company Bioconversion of a fermentable carbon source to 1,3-propanediol by a single microorganism
US5849970A (en) * 1995-06-23 1998-12-15 The Regents Of The University Of Colorado Materials and methods for the bacterial production of isoprene
FR2736927B1 (en) 1995-07-18 1997-10-17 Rhone Poulenc Fibres & Polymer ENZYMES HAVING AMIDASE ACTIVITY, GENETIC TOOLS AND HOST MICROORGANISMS FOR OBTAINING SAME AND HYDROLYSIS PROCESS USING THE SAME
US5573931A (en) 1995-08-28 1996-11-12 Michigan Biotechnology Institute Method for making succinic acid, bacterial variants for use in the process, and methods for obtaining variants
US5770435A (en) 1995-11-02 1998-06-23 University Of Chicago Mutant E. coli strain with increased succinic acid production
US5869301A (en) 1995-11-02 1999-02-09 Lockhead Martin Energy Research Corporation Method for the production of dicarboxylic acids
EP0883683A1 (en) 1996-02-27 1998-12-16 Michigan State University Cloning and expression of the gene encoding thermoanaerobacter ethanolicus 39e secondary-alcohol dehydrogenase and enzyme biochemical characterization
US5958745A (en) 1996-03-13 1999-09-28 Monsanto Company Methods of optimizing substrate pools and biosynthesis of poly-β-hydroxybutyrate-co-poly-β-hydroxyvalerate in bacteria and plants
DE69638265D1 (en) 1996-07-01 2010-11-11 Emmaus Foundation Inc BIOLOGICAL PREPARATION OF ACETIC ACID FROM EXHAUST GASES
KR100459818B1 (en) 1996-09-02 2004-12-03 이. 아이. 두퐁 드 느무르 앤드 컴퍼니 Process for the preparation of epsilon-caprolactam
US6117658A (en) 1997-02-13 2000-09-12 James Madison University Methods of making polyhydroxyalkanoates comprising 4-hydroxybutyrate monomer units
KR100516986B1 (en) 1997-02-19 2005-09-26 코닌클리즈케 디에스엠 엔.브이. Process for the preparation of caprolactam in the absence of catalysts by contacting 6-aminocaproic acid derivatives with superheated steam
US6274790B1 (en) 1997-04-14 2001-08-14 The University Of British Columbia Nucleic acids encoding a plant enzyme involved in very long chain fatty acid synthesis
KR19990013007A (en) 1997-07-31 1999-02-25 박원훈 Transformed Escherichia Coli S373 (BTCC 8818 P) and Production Method of Succinic Acid Using the Same
JPH11103863A (en) 1997-10-08 1999-04-20 Nippon Shokubai Co Ltd Maleate isomerase gene
US6280986B1 (en) 1997-12-01 2001-08-28 The United States Of America As Represented By The Secretary Of Agriculture Stabilization of pet operon plasmids and ethanol production in bacterial strains lacking lactate dehydrogenase and pyruvate formate lyase activities
US20030087381A1 (en) 1998-04-13 2003-05-08 University Of Georgia Research Foundation, Inc. Metabolically engineered organisms for enhanced production of oxaloacetate-derived biochemicals
MY121380A (en) 1998-04-13 2006-01-28 Univ Georgia Pyruvate carboxylase overexpression for enhanced production of oxaloacetate-derived biochemicals in microbial cells
US6159738A (en) 1998-04-28 2000-12-12 University Of Chicago Method for construction of bacterial strains with increased succinic acid production
DE19820652A1 (en) 1998-05-08 1999-11-11 Basf Ag Cationic ruthenium complexes used as catalyst for metathesis reactions
US6432686B1 (en) 1998-05-12 2002-08-13 E. I. Du Pont De Nemours And Company Method for the production of 1,3-propanediol by recombinant organisms comprising genes for vitamin B12 transport
US6444784B1 (en) 1998-05-29 2002-09-03 Exxonmobil Research & Engineering Company Wax crystal modifiers (LAW657)
AU5101599A (en) 1998-07-15 2000-02-07 E.I. Du Pont De Nemours And Company Tetrahydrofolate metabolism enzymes
DE19856136C2 (en) 1998-12-04 2002-10-24 Pasteur Institut Method and device for the selection of accelerated proliferation of living cells in suspension
EP1147229A2 (en) 1999-02-02 2001-10-24 Bernhard O. Palsson Methods for identifying drug targets based on genomic sequence data
US6686310B1 (en) 1999-02-09 2004-02-03 E. I. Du Pont De Nemours And Company High surface area sol-gel route prepared hydrogenation catalysts
US6365376B1 (en) 1999-02-19 2002-04-02 E. I. Du Pont De Nemours And Company Genes and enzymes for the production of adipic acid intermediates
WO2000052183A1 (en) 1999-03-05 2000-09-08 Monsanto Technology Llc Multigene expression vectors for the biosynthesis of products via multienzyme biological pathways
CA2374482C (en) 1999-05-21 2012-09-18 Cargill Dow Llc Methods and materials for the synthesis of organic products
US6852517B1 (en) 1999-08-30 2005-02-08 Wisconsin Alumni Research Foundation Production of 3-hydroxypropionic acid in recombinant organisms
US6660857B2 (en) 2000-02-03 2003-12-09 Dsm N.V. Process for the preparation of ε-caprolactam
US6878861B2 (en) 2000-07-21 2005-04-12 Washington State University Research Foundation Acyl coenzyme A thioesterases
BR0112251B1 (en) 2000-07-25 2013-04-09 Continuous methods for ethanol production from anaerobic bacterial fermentation of a gaseous substrate.
MXPA03004324A (en) 2000-11-20 2004-01-26 Cargill Inc 3-hydroxypropionic acid and other organic compounds.
CN1955299A (en) 2000-11-22 2007-05-02 内特尔沃克公司 Methods and materials for the synthesis of organic products
CN1358841A (en) 2000-12-11 2002-07-17 云南省微生物研究所 Yunnan streptin
CA2433529A1 (en) 2000-12-28 2002-07-11 Toyota Jidosha Kabushiki Kaisha Process for producing prenyl alcohol
JP4776146B2 (en) 2001-01-10 2011-09-21 ザ・ペン・ステート・リサーチ・ファンデーション Method and system for modeling cellular metabolism
US7127379B2 (en) 2001-01-31 2006-10-24 The Regents Of The University Of California Method for the evolutionary design of biochemical reaction networks
EP1381860A4 (en) 2001-03-01 2008-10-15 Univ California Models and methods for determining systemic properties of regulated reaction networks
US6743610B2 (en) 2001-03-30 2004-06-01 The University Of Chicago Method to produce succinic acid from raw hydrolysates
JP4630486B2 (en) 2001-05-28 2011-02-09 ダイセル化学工業株式会社 Novel (R) -2,3-butanediol dehydrogenase, method for producing the same, and method for producing optically active alcohol using the same
CA2356540A1 (en) 2001-08-30 2003-02-28 Emory University Expressed dna sequences involved in mitochondrial functions
US7256016B2 (en) 2001-11-02 2007-08-14 Rice University Recycling system for manipulation of intracellular NADH availability
JP4532116B2 (en) 2002-01-18 2010-08-25 ノボザイムズ エー/エス Alanine 2,3-aminomutase
EP1473368A4 (en) 2002-02-06 2006-01-25 Showa Denko Kk Alpha-substituted-alpha, beta-unsaturated carbonyl compound reductase gene
US20030224363A1 (en) 2002-03-19 2003-12-04 Park Sung M. Compositions and methods for modeling bacillus subtilis metabolism
AU2003222128A1 (en) 2002-03-29 2003-10-13 Genomatica, Inc. Human metabolic models and methods
WO2003095651A1 (en) 2002-05-10 2003-11-20 Kyowa Hakko Kogyo Co., Ltd. Process for producing mevalonic acid
US7856317B2 (en) 2002-06-14 2010-12-21 Genomatica, Inc. Systems and methods for constructing genomic-based phenotypic models
US8027821B2 (en) 2002-07-10 2011-09-27 The Penn State Research Foundation Method for determining gene knockouts
US7826975B2 (en) 2002-07-10 2010-11-02 The Penn State Research Foundation Method for redesign of microbial production systems
US7413878B2 (en) 2002-07-15 2008-08-19 Kosan Biosciences, Inc. Recombinant host cells expressing atoAD and capable of making a polyketide using a starter unit
KR101148255B1 (en) 2002-10-04 2012-08-08 다니스코 유에스 인크. Process for the biological production of 1,3-propanediol with high yield
EP1552472A4 (en) 2002-10-15 2008-02-20 Univ California Methods and systems to identify operational reaction pathways
WO2004044210A2 (en) 2002-11-06 2004-05-27 University Of Florida Materials and methods for the efficient production of acetate and other products
CN1802341A (en) 2003-01-13 2006-07-12 卡吉尔公司 Method for making industrial chemicals
US7432091B2 (en) 2003-02-24 2008-10-07 Research Institute Of Innovative Technology For The Earth Highly efficient hydrogen production method using microorganism
RU2268300C2 (en) 2003-04-07 2006-01-20 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" METHOD FOR PREPARING L-AMINO ACIDS BY USING MICROORGANISMS POSSESSING ENHANCED EXPRESSION OF pckA GENE
ATE462002T1 (en) 2003-07-29 2010-04-15 Res Inst Innovative Tech Earth TRANSFORMANTS OF A CORYNEFORM BACTERIA AND THEIR USE IN PROCESS FOR THE PRODUCTION OF DICARBONIC ACID
US7927859B2 (en) 2003-08-22 2011-04-19 Rice University High molar succinate yield bacteria by increasing the intracellular NADH availability
CN1852978A (en) 2003-09-17 2006-10-25 三菱化学株式会社 Process for producing non-amino organic acid
US7244610B2 (en) 2003-11-14 2007-07-17 Rice University Aerobic succinate production in bacteria
FR2864967B1 (en) 2004-01-12 2006-05-19 Metabolic Explorer Sa ADVANCED MICROORGANISM FOR THE PRODUCTION OF 1,2-PROPANEDIOL
EP2194139A1 (en) 2004-01-19 2010-06-09 DSM IP Assets B.V. Biochemical synthesis of 6 amino caproic acid
US7608700B2 (en) 2004-03-08 2009-10-27 North Carolina State University Lactobacillus acidophilus nucleic acid sequences encoding stress-related proteins and uses therefor
DE102004031177A1 (en) 2004-06-29 2006-01-19 Henkel Kgaa New odoriferous gene products from Bacillus licheniformis and improved biotechnological production processes based on them
US7262046B2 (en) 2004-08-09 2007-08-28 Rice University Aerobic succinate production in bacteria
JP2008510485A (en) * 2004-08-26 2008-04-10 ザ ペン ステイト リサーチ ファウンデーション Redesign method of microbial production system
WO2006031424A2 (en) 2004-08-27 2006-03-23 Rice University Mutant e. coli strain with increased succinic acid production
ES2444785T3 (en) 2004-09-09 2014-02-26 Research Institute Of Innovative Technology For The Earth DNA fragment that has a promoter function
WO2006034156A2 (en) 2004-09-17 2006-03-30 Rice University High succinate producing bacteria
WO2006041209A1 (en) 2004-10-14 2006-04-20 Sumitomo Chemical Company, Limited Method for producing 2-hydroxy-4-(methylthio)butanoic acid
US7569380B2 (en) 2004-12-22 2009-08-04 Rice University Simultaneous anaerobic production of isoamyl acetate and succinic acid
DE102005002127A1 (en) * 2005-01-17 2006-07-20 Basf Ag Process for the preparation of butadiene from n-butane
JP2006204255A (en) 2005-01-31 2006-08-10 Canon Inc ACETYL-CoA ACYLTRANSFERASE GENE-BROKEN POLYHYDROXYALKANOATE-PRODUCING MICROORGANISM, AND METHOD FOR PRODUCING POLYHYDROXYALKANOATE THEREWITH
US20090068207A1 (en) 2005-04-15 2009-03-12 Vascular Biogenics Ltd. Compositions Containing Beta 2-Glycoprotein I-Derived Peptides for the Prevention and/or Treatment of Vascular Disease
KR100676160B1 (en) 2005-08-19 2007-02-01 한국과학기술원 Microorganisms transformed with gene encoding malic enzyme and method for preparing succinic acid using the same
KR100679638B1 (en) 2005-08-19 2007-02-06 한국과학기술원 Microorganisms transformed with gene encoding formate ddehydrogenase d or e and method for preparing succinic acid using the same
JP2009507493A (en) 2005-09-09 2009-02-26 ジェノマティカ・インコーポレイテッド Methods and organisms for growth-linked succinate production
US9297028B2 (en) 2005-09-29 2016-03-29 Butamax Advanced Biofuels Llc Fermentive production of four carbon alcohols
UA96928C2 (en) 2005-10-26 2011-12-26 Э.И. Дю Пон Де Немур Энд Компани Fermentive production of four carbon alcohols
GB2433260A (en) 2005-12-16 2007-06-20 Mologic Ltd A selectable decarboxylase marker
US8962298B2 (en) 2006-05-02 2015-02-24 Butamax Advanced Biofuels Llc Recombinant host cell comprising a diol dehydratase
DE102006025821A1 (en) 2006-06-02 2007-12-06 Degussa Gmbh An enzyme for the production of Mehylmalonatsemialdehyd or Malonatsemialdehyd
US8017364B2 (en) 2006-12-12 2011-09-13 Butamax(Tm) Advanced Biofuels Llc Solvent tolerant microorganisms
JP2010515465A (en) 2007-01-12 2010-05-13 ザ リージェンツ オブ ザ ユニバーシティー オブ コロラド,ア ボディー コーポレート Compositions and methods for enhancing resistance to the production of organic chemicals produced by microorganisms
EP2137315B1 (en) 2007-03-16 2014-09-03 Genomatica, Inc. Compositions and methods for the biosynthesis of 1,4-butanediol and its precursors
EP2147111A4 (en) 2007-04-18 2010-06-23 Gevo Inc Engineered microorganisms for producing isopropanol
US20080274522A1 (en) 2007-05-02 2008-11-06 Bramucci Michael G Method for the production of 2-butanone
WO2008144060A2 (en) 2007-05-17 2008-11-27 Tetravitae Bioscience, Inc. Methods and compositions for producing solvents
EP2017344A1 (en) 2007-07-20 2009-01-21 Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO Production of itaconic acid
EP2171075A2 (en) 2007-07-23 2010-04-07 DSM IP Assets B.V. Butanol production in a eukaryotic cell
US7947483B2 (en) 2007-08-10 2011-05-24 Genomatica, Inc. Methods and organisms for the growth-coupled production of 1,4-butanediol
CN101903530A (en) 2007-10-12 2010-12-01 加利福尼亚大学董事会 Microorganism engineered to produce isopropanol
SG162265A1 (en) * 2007-12-13 2010-07-29 Danisco Us Inc Compositions and methods for producing isoprene
WO2009085278A1 (en) 2007-12-21 2009-07-09 Ls9, Inc. Methods and compositions for producing olefins
WO2009094485A1 (en) 2008-01-22 2009-07-30 Genomatica, Inc. Methods and organisms for utilizing synthesis gas or other gaseous carbon sources and methanol
CN102015995B (en) * 2008-03-03 2014-10-22 焦耳无限科技公司 Engineered CO2 fixing microorganisms producing carbon-based products of interest
CN103555643B (en) 2008-03-27 2016-08-10 基因组股份公司 For producing the microorganism of adipic acid and other compounds
US8173410B2 (en) * 2008-04-23 2012-05-08 Danisco Us Inc. Isoprene synthase variants for improved microbial production of isoprene
AU2009242615A1 (en) 2008-05-01 2009-11-05 Genomatica, Inc. Microorganisms for the production of methacrylic acid
US8129154B2 (en) 2008-06-17 2012-03-06 Genomatica, Inc. Microorganisms and methods for the biosynthesis of fumarate, malate, and acrylate
RU2505605C2 (en) 2008-06-30 2014-01-27 Дзе Гудйеар Тайр Энд Раббер Компани Isoprene polymers from renewable sources
WO2010006076A2 (en) 2008-07-08 2010-01-14 Opx Biotechnologies Inc. Methods, compositions and systems for biosynthetic bio production of 1,4-butanediol
WO2010022763A1 (en) 2008-08-25 2010-03-04 Metabolic Explorer Method for the preparation of 2-hydroxy-isobutyrate
WO2010030711A2 (en) * 2008-09-10 2010-03-18 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol
BRPI0918453A2 (en) 2008-09-15 2019-12-17 Danisco Us Inc systems using cell culture for isoprene production
SG169640A1 (en) * 2008-09-15 2011-04-29 Danisco Us Inc Increased isoprene production using mevalonate kinase and isoprene synthase
US8357826B2 (en) 2008-10-16 2013-01-22 Karl Kharas Methods and apparatus for synthesis of alcohols from syngas
WO2010068953A2 (en) 2008-12-12 2010-06-17 Metabolix Inc. Green process and compositions for producing poly(5hv) and 5 carbon chemicals
AU2009327490A1 (en) 2008-12-16 2011-07-28 Genomatica, Inc. Microorganisms and methods for conversion of syngas and other carbon sources to useful products
EP3318626B1 (en) * 2009-04-30 2020-01-15 Genomatica, Inc. Organisms for the production of 1,3-butanediol
MY195387A (en) 2009-06-04 2023-01-18 Genomatica Inc Microorganisms for the Production of 1,4-Butanediol and Related Methods
EP2495305A1 (en) 2009-10-30 2012-09-05 Daicel Corporation Transgenic microorganism provided with the ability to produce 1,3-butanediol, and usage therefor
CN109136161A (en) 2009-12-10 2019-01-04 基因组股份公司 Synthesis gas or other gaseous carbon sources and methanol are converted into the method and organism of 1,3 butylene glycol
CN103080324B (en) * 2010-05-05 2019-03-08 基因组股份公司 Microorganism and method for butadiene biosynthesis
MY162964A (en) * 2011-02-02 2017-07-31 Genomatica Inc Microorganisms and methods for the biosynthesis of butadiene
US9169486B2 (en) * 2011-06-22 2015-10-27 Genomatica, Inc. Microorganisms for producing butadiene and methods related thereto
US9169496B2 (en) * 2011-10-19 2015-10-27 Scientist of Fortune, S.A. Method for the enzymatic production of butadiene
US20160040172A1 (en) * 2013-03-15 2016-02-11 Genomatica, Inc. Microorganisms and methods for producing butadiene and related compounds by formate assimilation
US20150050708A1 (en) * 2013-03-15 2015-02-19 Genomatica, Inc. Microorganisms and methods for producing butadiene and related compounds by formate assimilation

Also Published As

Publication number Publication date
WO2011140171A2 (en) 2011-11-10
TWI575072B (en) 2017-03-21
KR20180005263A (en) 2018-01-15
CA2797409C (en) 2019-12-24
KR20190006103A (en) 2019-01-16
EP2566969A4 (en) 2014-01-15
CN106047782A (en) 2016-10-26
TW201139683A (en) 2011-11-16
US20110300597A1 (en) 2011-12-08
EP2566969B1 (en) 2019-09-04
AU2011248182A1 (en) 2012-11-15
CN103080324B (en) 2019-03-08
KR101814648B1 (en) 2018-01-04
US20180155742A1 (en) 2018-06-07
MX2012012827A (en) 2013-01-24
KR20130062939A (en) 2013-06-13
US9732361B2 (en) 2017-08-15
CA2797409A1 (en) 2011-11-10
TW201720931A (en) 2017-06-16
US8580543B2 (en) 2013-11-12
JP2016154551A (en) 2016-09-01
AU2016201231A1 (en) 2016-03-17
EP2566969A2 (en) 2013-03-13
US20140155567A1 (en) 2014-06-05
WO2011140171A3 (en) 2012-04-26
JP5911847B2 (en) 2016-04-27
US10487343B2 (en) 2019-11-26
CO6630182A2 (en) 2013-03-01
US20200299736A1 (en) 2020-09-24
CN103080324A (en) 2013-05-01
MX336229B (en) 2016-01-08
US20220025411A1 (en) 2022-01-27
JP2018196387A (en) 2018-12-13
SG185432A1 (en) 2012-12-28
BR112012028049A2 (en) 2015-11-24
JP2013524853A (en) 2013-06-20

Similar Documents

Publication Publication Date Title
SG10201503501TA (en) Microorganisms and methods for the biosynthesis of butadiene
EP2670852A4 (en) Microorganisms and methods for the biosynthesis of butadiene
SG11201403276TA (en) Modified microorganisms and methods of making butadiene using same
EP3611254C0 (en) Microorganisms and methods for the biosynthesis of hexamethylenediamine
HK1200190A1 (en) Targeted enzyme compounds and uses thereof
EP2529011A4 (en) Microorganisms and methods for the biosynthesis of p-toluate and terephthalate
EP2742126A4 (en) Compositions and methods for the biosynthesis of vanillin or vanillin beta-d-glucoside
EP2592920A4 (en) Microorganism compositions and methods
GB201004179D0 (en) Enzyme inhibitors
EP2619715A4 (en) Methods and apparatuses for context determination
HK1178149A1 (en) Pyrazol-4-yl-heterocyclyl-carboxamide compounds and methods of use -4---
EP2401307A4 (en) Methods of preparing renewable butadiene and renewable isoprene
GB201004178D0 (en) Enzyme inhibitors
EP2663864B8 (en) Immunodiversity assessment method and its use
EP2569560A4 (en) Valve assembly and method of using same
EP2596343A4 (en) Biosensor apparatuses and methods thereof
EP2616598A4 (en) Faucet extending apparatus and method
GB201019086D0 (en) Bacterial methods
EP2566876A4 (en) Methods and compounds for inhibiting glycosyltransferases
WO2011153429A9 (en) Methods of treatment
EP2668731A4 (en) Methods and arrangements for transmit mode adaptation
EP2445131A4 (en) Pre-coding method and transmitter
EP2764121A4 (en) E1 enzyme mutants and uses thereof
EP2646564A4 (en) Processes for isolating microorganisms
EP2728001A4 (en) Enzyme function modification method and enzyme variant thereof